• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\CG11425

General Information
Symbol	Dmel\CG11425	Species	D. melanogaster
Name		Annotation symbol	CG11425
Feature type	protein_coding_gene	FlyBase ID	FBgn0037167
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	79E4-79E4	Sequence location	3L:22,467,895..22,468,892 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG11425 (FBgn0037167). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: phosphatidate phosphatase activity. It is reported to be involved in the biological process: dephosphorylation. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Phosphatidic acid phosphatase type 2/haloperoxidase; Phosphatidic acid phosphatase/chloroperoxidase, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of no expression detected. Peak expression observed during early larval stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult hindgut. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval central nervous system, larval hindgut, larval/adult fat body, virgin spermatheca, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1633796_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG11425. Gene sequence location is 3L:22467895..22468892.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 79E4-79E4   Limits computationally determined from genome sequence between P{lacW}l(3)j1B10j1B10 and P{lacW}l(3)j2C4j2C4
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG11425 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.45
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG11425-RA FBtr0078507  NM_141138   998   305
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG11425-PA   FBpp0078159   34.3   305   8.09     NP_649395   AAF51832
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Phosphatidic acid phosphatase type 2/haloperoxidase (IPR000326) Phosphatidic acid phosphatase/chloroperoxidase, N-terminal (IPR016118)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAF51832   BT031192   EC054658   ES695738
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VNT8
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult hindgut. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval central nervous system, larval hindgut, larval/adult fat body, virgin spermatheca, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    151.9 Larval Midgut    5.7 Larval Hindgut    328.5 Larval Malpighian Tubules    9.4 Larval Fat Body    185.6 Larval Salivary Gland    8.9 Larval Trachea    0.525 Larval Carcass    13.1 Adult Head    163.3 Adult Eye    72.3 Adult Brain    68.1 Adult Thoracic-Abdominal Ganglion    74.9 Adult Crop    98.6 Adult Midgut    6.3 Adult Hindgut    721.3 Adult Malpighian Tubules    7.4 Adult Fat Body    145.9 Adult Salivary Gland    11.1 Adult Heart    13.95 Adult VirginFemale Spermatheca    138.9 Adult InseminatedFemale Spermatheca    53 Adult Ovary    2.9 Adult Testis    3.7 Adult Male Accessory Gland    5.1 Adult Carcass    104.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    151.9 Larval Midgut    5.7 Larval Hindgut    328.5 Larval Malpighian Tubules    9.4 Larval Fat Body    185.6 Larval Salivary Gland    8.9 Larval Trachea    0.525 Larval Carcass    13.1 Adult Head    163.3 Adult Eye    72.3 Adult Brain    68.1 Adult Thoracic-Abdominal Ganglion    74.9 Adult Crop    98.6 Adult Midgut    6.3 Adult Hindgut  (721.3) Adult Malpighian Tubules    7.4 Adult Fat Body    145.9 Adult Salivary Gland    11.1 Adult Heart    13.95 Adult VirginFemale Spermatheca    138.9 Adult InseminatedFemale Spermatheca    53 Adult Ovary    2.9 Adult Testis    3.7 Adult Male Accessory Gland    5.1 Adult Carcass    104.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    151.9 Larval Midgut    5.7 Larval Hindgut    328.5 Larval Malpighian Tubules    9.4 Larval Fat Body    185.6 Larval Salivary Gland    8.9 Larval Trachea    0.525 Larval Carcass    13.1 Adult Head    163.3 Adult Eye    72.3 Adult Brain    68.1 Adult Thoracic-Abdominal Ganglion    74.9 Adult Crop    98.6 Adult Midgut    6.3 Adult Hindgut    721.3 Adult Malpighian Tubules    7.4 Adult Fat Body    145.9 Adult Salivary Gland    11.1 Adult Heart    13.95 Adult VirginFemale Spermatheca    138.9 Adult InseminatedFemale Spermatheca    53 Adult Ovary    2.9 Adult Testis    3.7 Adult Male Accessory Gland    5.1 Adult Carcass    104.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    151.9 Larval Midgut    5.7 Larval Hindgut    328.5 Larval Malpighian Tubules    9.4 Larval Fat Body    185.6 Larval Salivary Gland    8.9 Larval Trachea    0.525 Larval Carcass    13.1 Adult Head    163.3 Adult Eye    72.3 Adult Brain    68.1 Adult Thoracic-Abdominal Ganglion    74.9 Adult Crop    98.6 Adult Midgut    6.3 Adult Hindgut    721.3 Adult Malpighian Tubules    7.4 Adult Fat Body    145.9 Adult Salivary Gland    11.1 Adult Heart    13.95 Adult VirginFemale Spermatheca    138.9 Adult InseminatedFemale Spermatheca    53 Adult Ovary    2.9 Adult Testis    3.7 Adult Male Accessory Gland    5.1 Adult Carcass    104.5 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    151.9 Larval Midgut    5.7 Larval Hindgut    328.5 Larval Malpighian Tubules    9.4 Larval Fat Body    185.6 Larval Salivary Gland    8.9 Larval Trachea    0.525 Larval Carcass    13.1 Adult Head    163.3 Adult Eye    72.3 Adult Brain    68.1 Adult Thoracic-Abdominal Ganglion    74.9 Adult Crop    98.6 Adult Midgut    6.3 Adult Hindgut    721.3 Adult Malpighian Tubules    7.4 Adult Fat Body    145.9 Adult Salivary Gland    11.1 Adult Heart    13.95 Adult VirginFemale Spermatheca    138.9 Adult InseminatedFemale Spermatheca    53 Adult Ovary    2.9 Adult Testis    3.7 Adult Male Accessory Gland    5.1 Adult Carcass    104.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    151.9 Larval Midgut    5.7 Larval Hindgut    328.5 Larval Malpighian Tubules    9.4 Larval Fat Body    185.6 Larval Salivary Gland    8.9 Larval Trachea    0.525 Larval Carcass    13.1 Adult Head    163.3 Adult Eye    72.3 Adult Brain    68.1 Adult Thoracic-Abdominal Ganglion    74.9 Adult Crop    98.6 Adult Midgut    6.3 Adult Hindgut  721.3 Adult Malpighian Tubules    7.4 Adult Fat Body    145.9 Adult Salivary Gland    11.1 Adult Heart    13.95 Adult VirginFemale Spermatheca    138.9 Adult InseminatedFemale Spermatheca    53 Adult Ovary    2.9 Adult Testis    3.7 Adult Male Accessory Gland    5.1 Adult Carcass    104.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    151.9 Larval Midgut    5.7 Larval Hindgut    328.5 Larval Malpighian Tubules    9.4 Larval Fat Body    185.6 Larval Salivary Gland    8.9 Larval Trachea    0.525 Larval Carcass    13.1 Adult Head    163.3 Adult Eye    72.3 Adult Brain    68.1 Adult Thoracic-Abdominal Ganglion    74.9 Adult Crop    98.6 Adult Midgut    6.3 Adult Hindgut    721.3 Adult Malpighian Tubules    7.4 Adult Fat Body    145.9 Adult Salivary Gland    11.1 Adult Heart    13.95 Adult VirginFemale Spermatheca    138.9 Adult InseminatedFemale Spermatheca    53 Adult Ovary    2.9 Adult Testis    3.7 Adult Male Accessory Gland    5.1 Adult Carcass    104.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    151.9 Larval Midgut    5.7 Larval Hindgut    328.5 Larval Malpighian Tubules    9.4 Larval Fat Body    185.6 Larval Salivary Gland    8.9 Larval Trachea    0.525 Larval Carcass    13.1 Adult Head    163.3 Adult Eye    72.3 Adult Brain    68.1 Adult Thoracic-Abdominal Ganglion    74.9 Adult Crop    98.6 Adult Midgut    6.3 Adult Hindgut    721.3 Adult Malpighian Tubules    7.4 Adult Fat Body    145.9 Adult Salivary Gland    11.1 Adult Heart    13.95 Adult VirginFemale Spermatheca    138.9 Adult InseminatedFemale Spermatheca    53 Adult Ovary    2.9 Adult Testis    3.7 Adult Male Accessory Gland    5.1 Adult Carcass    104.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    163.3   NA  Eye    72.3   NA  Brain    68.1   151.9  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    74.9   NA  Crop    98.6   5.7  Midgut    6.3   328.5  Hindgut    721.3   9.4  Malpighian Tubules    7.4   185.6  Fat Body    145.9   8.9  Salivary Gland    no informative data   NA  Heart    13.95   0.525  Trachea    NA   NA  VirginFemale Spermatheca    138.9   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    2.9   NA  Testis    3.7   NA  Male Accessory Gland    5.1   no informative data  Carcass    104.5 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    11 central nervous system, pupae P8    7 head, virgin 1-day female    27 head, virgin 4-day female    4 head, virgin 20-day female    15 head, mated 1-day female    10 head, mated 4-day female    18 head, mated 20-day female    18 head, mated 1-day male    3 head, mated 4-day male    4 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    2 fat body, white prepupae    1 fat body, pupae P8    4 carcass, larvae L3 wandering    3 carcass, 1-day adult    11 carcass, 4-day adult    10 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    11 central nervous system, pupae P8    7 head, virgin 1-day female  (27) head, virgin 4-day female    4 head, virgin 20-day female    15 head, mated 1-day female    10 head, mated 4-day female    18 head, mated 20-day female    18 head, mated 1-day male    3 head, mated 4-day male    4 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    2 fat body, white prepupae    1 fat body, pupae P8    4 carcass, larvae L3 wandering    3 carcass, 1-day adult    11 carcass, 4-day adult    10 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    11 central nervous system, pupae P8    7 head, virgin 1-day female    27 head, virgin 4-day female    4 head, virgin 20-day female    15 head, mated 1-day female    10 head, mated 4-day female    18 head, mated 20-day female    18 head, mated 1-day male    3 head, mated 4-day male    4 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    2 fat body, white prepupae    1 fat body, pupae P8    4 carcass, larvae L3 wandering    3 carcass, 1-day adult    11 carcass, 4-day adult    10 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    11 central nervous system, pupae P8    7 head, virgin 1-day female    27 head, virgin 4-day female    4 head, virgin 20-day female    15 head, mated 1-day female    10 head, mated 4-day female    18 head, mated 20-day female    18 head, mated 1-day male    3 head, mated 4-day male    4 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    2 fat body, white prepupae    1 fat body, pupae P8    4 carcass, larvae L3 wandering    3 carcass, 1-day adult    11 carcass, 4-day adult    10 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    11 central nervous system, pupae P8    7 head, virgin 1-day female    27 head, virgin 4-day female    4 head, virgin 20-day female    15 head, mated 1-day female    10 head, mated 4-day female    18 head, mated 20-day female    18 head, mated 1-day male    3 head, mated 4-day male    4 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    2 fat body, white prepupae    1 fat body, pupae P8    4 carcass, larvae L3 wandering    3 carcass, 1-day adult    11 carcass, 4-day adult    10 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    11 central nervous system, pupae P8    7 head, virgin 1-day female  27 head, virgin 4-day female    4 head, virgin 20-day female    15 head, mated 1-day female    10 head, mated 4-day female    18 head, mated 20-day female    18 head, mated 1-day male    3 head, mated 4-day male    4 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    2 fat body, white prepupae    1 fat body, pupae P8    4 carcass, larvae L3 wandering    3 carcass, 1-day adult    11 carcass, 4-day adult    10 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    11 central nervous system, pupae P8    7 head, virgin 1-day female    27 head, virgin 4-day female    4 head, virgin 20-day female    15 head, mated 1-day female    10 head, mated 4-day female    18 head, mated 20-day female    18 head, mated 1-day male    3 head, mated 4-day male    4 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    2 fat body, white prepupae    1 fat body, pupae P8    4 carcass, larvae L3 wandering    3 carcass, 1-day adult    11 carcass, 4-day adult    10 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    11 central nervous system, pupae P8    7 head, virgin 1-day female    27 head, virgin 4-day female    4 head, virgin 20-day female    15 head, mated 1-day female    10 head, mated 4-day female    18 head, mated 20-day female    18 head, mated 1-day male    3 head, mated 4-day male    4 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    2 fat body, white prepupae    1 fat body, pupae P8    4 carcass, larvae L3 wandering    3 carcass, 1-day adult    11 carcass, 4-day adult    10 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of no expression detected. Peak expression observed during early larval stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    1 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    67 larva L2    43 larva L3 12hr old    63 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    16 white prepupae new    5 white prepupae 12hr    8 white prepupae 24hr    13 pupae 2d postWPP    12 pupae 3d postWPP    3 pupae 4d postWPP    11 adult male 01day    6 adult male 05day    5 adult male 30day    8 adult female 01day    7 adult female 05day    6 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    1 embryo 20-22hr    6 embryo 22-24hr    7 larva L1  (67) larva L2  (43) larva L3 12hr old  (63) larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    16 white prepupae new    5 white prepupae 12hr    8 white prepupae 24hr    13 pupae 2d postWPP    12 pupae 3d postWPP    3 pupae 4d postWPP    11 adult male 01day    6 adult male 05day    5 adult male 30day    8 adult female 01day    7 adult female 05day    6 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    1 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    67 larva L2    43 larva L3 12hr old    63 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    16 white prepupae new    5 white prepupae 12hr    8 white prepupae 24hr    13 pupae 2d postWPP    12 pupae 3d postWPP    3 pupae 4d postWPP    11 adult male 01day    6 adult male 05day    5 adult male 30day    8 adult female 01day    7 adult female 05day    6 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    1 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    67 larva L2    43 larva L3 12hr old    63 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    16 white prepupae new    5 white prepupae 12hr    8 white prepupae 24hr    13 pupae 2d postWPP    12 pupae 3d postWPP    3 pupae 4d postWPP    11 adult male 01day    6 adult male 05day    5 adult male 30day    8 adult female 01day    7 adult female 05day    6 adult female 30day    21 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    1 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    67 larva L2    43 larva L3 12hr old    63 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    16 white prepupae new    5 white prepupae 12hr    8 white prepupae 24hr    13 pupae 2d postWPP    12 pupae 3d postWPP    3 pupae 4d postWPP    11 adult male 01day    6 adult male 05day    5 adult male 30day    8 adult female 01day    7 adult female 05day    6 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    1 embryo 20-22hr    6 embryo 22-24hr    7 larva L1  (67) larva L2  (43) larva L3 12hr old  (63) larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    16 white prepupae new    5 white prepupae 12hr    8 white prepupae 24hr    13 pupae 2d postWPP    12 pupae 3d postWPP    3 pupae 4d postWPP    11 adult male 01day    6 adult male 05day    5 adult male 30day    8 adult female 01day    7 adult female 05day    6 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    1 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    67 larva L2    43 larva L3 12hr old    63 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    16 white prepupae new    5 white prepupae 12hr    8 white prepupae 24hr    13 pupae 2d postWPP    12 pupae 3d postWPP    3 pupae 4d postWPP    11 adult male 01day    6 adult male 05day    5 adult male 30day    8 adult female 01day    7 adult female 05day    6 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    1 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    67 larva L2    43 larva L3 12hr old    63 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    16 white prepupae new    5 white prepupae 12hr    8 white prepupae 24hr    13 pupae 2d postWPP    12 pupae 3d postWPP    3 pupae 4d postWPP    11 adult male 01day    6 adult male 05day    5 adult male 30day    8 adult female 01day    7 adult female 05day    6 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    10 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    11 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    2 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    1 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    10 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    11 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    2 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    1 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    10 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    11 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    2 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    1 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    10 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    11 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    2 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    1 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    10 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    11 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    2 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    1 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    10 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    11 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    2 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    1 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    10 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    11 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    2 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    1 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    10 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    11 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    2 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    1 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_04 mE1_20_mRNA_expression_cluster_17
External Data & Images
Linkouts	BDGP expression data • GH04282 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037167 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11425-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG11425GD2782 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG11425 Class Mutagen Stocks Known lesion CG11425MB10743 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG11425 Class Mutagen Stocks Known lesion CG11425GD2782 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG11425KK110682 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD2782} NA P{KK110682} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap binary system Mi{ET1}CG11425MB10743 No
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
phosphatidate phosphatase activity inferred from sequence or structural similarity with mouse Ppap2a (FlyBase, 1992-) non-traceable author statement (Morrison et al., 2000)
Biological Process
CV term Evidence References
dephosphorylation non-traceable author statement (Morrison et al., 2000)
Cellular Component
CV term Evidence References
membrane inferred from electronic annotation with InterPro:IPR000326 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG11425 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0037167 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40472
Orthologs
OrthoDB Orthologs (55) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6DJKGW Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search EOG6KPS6Z Arthropod inclusive ortholog search EOG6WWQ1H Metazoa inclusive ortholog search EOG6TBH5Q
Orthologs in Drosophila Species (EOG6DJKGW)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG11425     Drosophila simulans   Dsim\GD15032 Y   Drosophila sechellia   Dsec\GM22449 Y   Drosophila erecta   Dere\GG16259 Y   Drosophila yakuba   Dyak\GE23020     Drosophila yakuba   Dyak\GE19507 Y   Drosophila ananassae   Dana\GF10981 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA10998 Y   Drosophila persimilis   Dper\GL23176 Y   Drosophila willistoni   Dwil\GK16762 Y   Drosophila virilis   Dvir\GJ11639 Y   Drosophila mojavensis   Dmoj\GI11384 Y   Drosophila grimshawi   Dgri\GH16696 Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (EOG6KPS6Z)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB49207 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013741 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH23602 Y Atta cephalotes Leafcutter ant  Acep\ACEP14034 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO21272 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL18423 Y Linepithema humile Argentine ant  Lhum\LH16928 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB19000 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI005610 Y Bombyx mori Silkmoth  Bmor\BGIBMGA003966 Y Pediculus humanus Human body louse  Phum\PHUM389600 Y Tribolium castaneum Red flour beetle  Tcas\TC015891 Y Tribolium castaneum Red flour beetle  Tcas\GLEAN_15830 Y
Orthologs in non-Insect Arthropods (EOG6WWQ1H)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_319296 Y Daphnia pulex Water flea  Dpux\JGI_V11_197078 Y Daphnia pulex Water flea  Dpux\JGI_V11_319297 Y Daphnia pulex Water flea  Dpux\JGI_V11_319295 Y Ixodes scapularis Deer tick  Isca\ISCW015634 Y
Orthologs in non-Arthropod Metazoa (EOG6TBH5Q)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\F13E6.5 Y Caenorhabditis elegans Nematode  Cele\F53C3.13 Y Caenorhabditis elegans Nematode  Cele\T28D9.3 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_011127gn Y Danio rerio Zebrafish  Drer\ENSDARG00000053381 Y Danio rerio Zebrafish  Drer\ENSDARG00000002231 Y Danio rerio Zebrafish  Drer\ppap2b Y Danio rerio Zebrafish  Drer\zgc:158309 Y Danio rerio Zebrafish  Drer\CH211-206A19.2 Y Danio rerio Zebrafish  Drer\ENSDARG00000079790 Y Xenopus tropicalis Western clawed frog  Xtro\ppap2a Y Xenopus tropicalis Western clawed frog  Xtro\ppap2b Y Xenopus tropicalis Western clawed frog  Xtro\ppap2c Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000017268 Y Gallus gallus Domestic chicken  Ggal\PPAP2B Y Gallus gallus Domestic chicken  Ggal\PPAP2A Y Mus musculus House mouse  Mmus\ENSMUSG00000021759 Y Mus musculus House mouse  Mmus\Ppap2b Y Rattus norvegicus Norway rat  Rnor\Ppap2b Y Rattus norvegicus Norway rat  Rnor\Ppap2c Y Rattus norvegicus Norway rat  Rnor\Ppap2a Y Homo sapiens Human  Hsap\PPAP2C Y Homo sapiens Human  Hsap\PPAP2B Y Homo sapiens Human  Hsap\PPAP2A Y
Human Orthologs (3)
Gene OMIM HGNC Hsap\PPAP2C     Hsap\PPAP2B     Hsap\PPAP2A
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD15032 Drosophila sechellia Dsec\GM22449 Drosophila erecta Dere\GG16259 Drosophila yakuba Dyak\GE19507 Drosophila ananassae Dana\GF10981 Drosophila pseudoobscura pseudoobscura Dpse\GA10998 Drosophila persimilis Dper\GL23176 Drosophila willistoni Dwil\GK16762 Drosophila virilis Dvir\GJ11639 Drosophila mojavensis Dmoj\GI11384 Drosophila grimshawi Dgri\GH16696
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	27846 w1118; Mi{ET1}CG11425MB10743
VDRC	v103037 P{KK110682}VIE-260B v8458 w1118; P{GD2782}v8458/TM3
Genomic Clones ( 2 )
	BACR02K11 BACR22C11 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 2 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH04282
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	EC054658
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0037167 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40472
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_141138 RefSeq (Proteins) • NP_649395 DDBJ / EMBL / GenBank • AAF51832 Entrez Gene - A searchable database of RefSeq genes. • 40472 UniProtKB/TrEMBL • Q9VNT8
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Phosphatidic acid phosphatase type 2/haloperoxidase (IPR000326) Phosphatidic acid phosphatase/chloroperoxidase, N-terminal (IPR016118) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GH04282
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0037167 DRSC - Results from RNAi screens. • FBgn0037167 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037167 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11425-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0037167 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40472 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40472 modMine - Data generated by the modENCODE project. • FBgn0037167
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	CG11425 (Dionne et al., 2006, Garcia-Murillas et al., 2006, Rynes et al., 2012, Garcia-Murillas et al., 2006, Bao and Friedrich, 2009, Keleman et al., 2009.8.5, Dalton et al., 2010) LPP-like (Garcia-Murillas et al., 2006) WUN-like (Morrison et al., 2000)
Name Synonym
Secondary FlyBase IDs
References ( 22 )
Generate a list of	All references relating to this gene ( 22 )
List References by type	Research paper  ( 7 ) Supplementary material  ( 6 ) Personal communication to FlyBase  ( 5 ) FlyBase analysis  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 1 )
	Rynes et al., 2012, Mol. Cell. Biol. 32(19): 3949--3962 Activating transcription factor 3 regulates immune and metabolic homeostasis. [FBrf0219385] Show all research papers ...