Amino acid transporter - downregulation within the fat body causes a global growth defect involving TSC/TOR signaling in the fat body and a remote inhibition of organismal growth
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.45
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Comment: maternally deposited
Comment: rapidly degraded
Comment: Thorax and abdomen assayed together.
Comment: Thorax and abdomen assayed together.
slif transcript is detected in most larval tissues but high expression is observed in the gut and the fat body.
slif protein is localized primarily to the cell surface, with peak levels just before the plasma membrane, in fat body cells.
GBrowse - Visual display of RNA-Seq signals
View Dmel\slif in GBrowse 23-47
3-44.0
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Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: slif CG11128
Identification: in a screen for growth modifiers.
Disruption of slif function in the fat body results in a developmental growth defect similar to that seen under amino acid deprivation.