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Gene Dmel\slif

General Information
Symbol	Dmel\slif	Species	D. melanogaster
Name	slimfast	Annotation symbol	CG11128
Feature type	protein_coding_gene	FlyBase ID	FBgn0037203
Gene Model Status	Current	Stock availability	13 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	80B2-80B2	Sequence location	3L:22,874,146..22,886,929 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene slimfast is referred to in FlyBase by the symbol Dmel\slif (CG11128, FBgn0037203). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: cationic amino acid transmembrane transporter activity. There is experimental evidence that it is involved in the biological process: lipid metabolic process; growth; amino acid transport. 14 alleles are reported. The phenotypes of these alleles are annotated with: larva; embryonic/larval fat body; wing; embryonic/larval neuroblast. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Amino acid permease domain; Amino acid/polyamine transporter I; Cationic amino acid transporter. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 00-06 and 18-24 hour embryonic stages, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, larval/adult Malpighian tubules, adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult hindgut, larval salivary gland, larval trachea, adult testis, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1630957_s_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of slif. Gene sequence location is 3L:22874146..22886929.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01	Sequence features HFA11635 BKN45458 BKN21694
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 80B2-80B2   Limits computationally determined from genome sequence between P{lacW}l(3)j1B10j1B10 and P{lacW}l(3)j2C4j2C4
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\slif for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) slif-RA FBtr0078555  NM_168977   2751   604 slif-RB FBtr0078557  NM_168978   2531   604 slif-RC FBtr0078556  NM_141171   2658   604
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein slif-PA   FBpp0078206   66.0   604   6.16     NP_730764   AAF51881 slif-PB   FBpp0078208   66.0   604   6.16     NP_730765   AAF51880 slif-PC   FBpp0078207   66.0   604   6.16     NP_649428   AAF51882
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Cationic amino acid transporter (IPR015606) Amino acid/polyamine transporter I (IPR002293) Amino acid permease domain (IPR004841)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA941656   AE014296 AAF51880   AE014296 AAF51881   AE014296 AAF51882   AI238254   AI295993   AI297645   AI297710   AI456010   AI457030   AW943378   AY094824 AAM11177   BH740790   BI239245   BI352631   BI356290   BI357982   BI372818   BI373298   BI564086   BI584240   BI591235   BI615757   BI618291   CK135423   CL632140   CO183304   CO188870   CO288237   CO289826   CO304994   CO317190   CO345401   CZ480920   CZ483003   CZ484106   CZ484107   CZ486422   CZ487905   CZ487906   CZ488881   EC057869   EC058647   EC058848   EC214570   EC225558   EC244809   EC252716   EV593049   EV598618   GH746337   GH761418   GH763201   GH763883   GH768245   GH778280   GH780667   GH799007   GH800054   GH802990   GH806073   GH808948   GH812894   GH818873   GH824661   GH825659   GH829558   GH834595   GH848295   GH851714   GH862652   GH868430   GH885457   GH893293   GH895460   GH900368   GH905612   GH913255   GH936565   GO254457
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VNP7
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference larval stage   organism | ubiquitous   (Colombani et al., 2003)
Additional Descriptive Data
	slif transcript is detected in most larval tissues but high expression is observed in the gut and the fat body. (Colombani et al., 2003)
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0037203    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0037203 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 00-06 and 18-24 hour embryonic stages, during early pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0037203 expression level Developmental Stage   Expression Level embryo 00-02hr    7096 embryo 02-04hr    282 embryo 04-06hr    123 embryo 06-08hr    77 embryo 08-10hr    99 embryo 10-12hr    78 embryo 12-14hr    125 embryo 14-16hr    635 embryo 16-18hr    3372 embryo 18-20hr    5122 embryo 20-22hr    3504 embryo 22-24hr    3862 larva L1    1602 larva L2    1244 larva L3 12hr old    1036 larva L3 puffstage 1-2    1717 larva L3 puffstage 3-6    1332 larva L3 puffstage 7-9    2888 white prepupae new    6480 white prepupae 12hr    995 white prepupae 24hr    121 pupae 2d postWPP    351 pupae 3d postWPP    951 pupae 4d postWPP    1942 adult male 01day    1023 adult male 05day    968 adult male 30day    836 adult female 01day    3900 adult female 05day    5966 adult female 30day    5649 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (7096) embryo 02-04hr  (282) embryo 04-06hr  (123) embryo 06-08hr    77 embryo 08-10hr    99 embryo 10-12hr    78 embryo 12-14hr  (125) embryo 14-16hr  (635) embryo 16-18hr  (3372) embryo 18-20hr  (5122) embryo 20-22hr  (3504) embryo 22-24hr  (3862) larva L1  (1602) larva L2  (1244) larva L3 12hr old  (1036) larva L3 puffstage 1-2  (1717) larva L3 puffstage 3-6  (1332) larva L3 puffstage 7-9  (2888) white prepupae new  (6480) white prepupae 12hr  (995) white prepupae 24hr  (121) pupae 2d postWPP  (351) pupae 3d postWPP  (951) pupae 4d postWPP  (1942) adult male 01day  (1023) adult male 05day  (968) adult male 30day  (836) adult female 01day  (3900) adult female 05day  (5966) adult female 30day  (5649) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (7096) embryo 02-04hr    282 embryo 04-06hr    123 embryo 06-08hr    77 embryo 08-10hr    99 embryo 10-12hr    78 embryo 12-14hr    125 embryo 14-16hr    635 embryo 16-18hr  (3372) embryo 18-20hr  (5122) embryo 20-22hr  (3504) embryo 22-24hr  (3862) larva L1  (1602) larva L2    1244 larva L3 12hr old    1036 larva L3 puffstage 1-2  (1717) larva L3 puffstage 3-6    1332 larva L3 puffstage 7-9  (2888) white prepupae new  (6480) white prepupae 12hr    995 white prepupae 24hr    121 pupae 2d postWPP    351 pupae 3d postWPP    951 pupae 4d postWPP  (1942) adult male 01day    1023 adult male 05day    968 adult male 30day    836 adult female 01day  (3900) adult female 05day  (5966) adult female 30day  (5649) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    7096 embryo 02-04hr    282 embryo 04-06hr    123 embryo 06-08hr    77 embryo 08-10hr    99 embryo 10-12hr    78 embryo 12-14hr    125 embryo 14-16hr    635 embryo 16-18hr    3372 embryo 18-20hr    5122 embryo 20-22hr    3504 embryo 22-24hr    3862 larva L1    1602 larva L2    1244 larva L3 12hr old    1036 larva L3 puffstage 1-2    1717 larva L3 puffstage 3-6    1332 larva L3 puffstage 7-9    2888 white prepupae new    6480 white prepupae 12hr    995 white prepupae 24hr    121 pupae 2d postWPP    351 pupae 3d postWPP    951 pupae 4d postWPP    1942 adult male 01day    1023 adult male 05day    968 adult male 30day    836 adult female 01day    3900 adult female 05day    5966 adult female 30day    5649 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    7096 embryo 02-04hr    282 embryo 04-06hr    123 embryo 06-08hr    77 embryo 08-10hr    99 embryo 10-12hr    78 embryo 12-14hr    125 embryo 14-16hr    635 embryo 16-18hr    3372 embryo 18-20hr    5122 embryo 20-22hr    3504 embryo 22-24hr    3862 larva L1    1602 larva L2    1244 larva L3 12hr old    1036 larva L3 puffstage 1-2    1717 larva L3 puffstage 3-6    1332 larva L3 puffstage 7-9    2888 white prepupae new    6480 white prepupae 12hr    995 white prepupae 24hr    121 pupae 2d postWPP    351 pupae 3d postWPP    951 pupae 4d postWPP    1942 adult male 01day    1023 adult male 05day    968 adult male 30day    836 adult female 01day    3900 adult female 05day    5966 adult female 30day    5649 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0037203 expression level Developmental Stage   Expression Level embryo 00-02hr    7096 embryo 02-04hr    282 embryo 04-06hr    123 embryo 06-08hr    77 embryo 08-10hr    99 embryo 10-12hr    78 embryo 12-14hr    125 embryo 14-16hr    635 embryo 16-18hr    3372 embryo 18-20hr    5122 embryo 20-22hr    3504 embryo 22-24hr    3862 larva L1    1602 larva L2    1244 larva L3 12hr old    1036 larva L3 puffstage 1-2    1717 larva L3 puffstage 3-6    1332 larva L3 puffstage 7-9    2888 white prepupae new    6480 white prepupae 12hr    995 white prepupae 24hr    121 pupae 2d postWPP    351 pupae 3d postWPP    951 pupae 4d postWPP    1942 adult male 01day    1023 adult male 05day    968 adult male 30day    836 adult female 01day    3900 adult female 05day    5966 adult female 30day    5649 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (7096) embryo 02-04hr  (282) embryo 04-06hr  123 embryo 06-08hr    77 embryo 08-10hr    99 embryo 10-12hr    78 embryo 12-14hr  125 embryo 14-16hr  (635) embryo 16-18hr  (3372) embryo 18-20hr  (5122) embryo 20-22hr  (3504) embryo 22-24hr  (3862) larva L1  (1602) larva L2  (1244) larva L3 12hr old  (1036) larva L3 puffstage 1-2  (1717) larva L3 puffstage 3-6  (1332) larva L3 puffstage 7-9  (2888) white prepupae new  (6480) white prepupae 12hr  (995) white prepupae 24hr  121 pupae 2d postWPP  (351) pupae 3d postWPP  (951) pupae 4d postWPP  (1942) adult male 01day  (1023) adult male 05day  (968) adult male 30day  (836) adult female 01day  (3900) adult female 05day  (5966) adult female 30day  (5649) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (7096) embryo 02-04hr    282 embryo 04-06hr    123 embryo 06-08hr    77 embryo 08-10hr    99 embryo 10-12hr    78 embryo 12-14hr    125 embryo 14-16hr    635 embryo 16-18hr  (3372) embryo 18-20hr  (5122) embryo 20-22hr  (3504) embryo 22-24hr  (3862) larva L1  1602 larva L2    1244 larva L3 12hr old    1036 larva L3 puffstage 1-2  1717 larva L3 puffstage 3-6    1332 larva L3 puffstage 7-9  (2888) white prepupae new  (6480) white prepupae 12hr    995 white prepupae 24hr    121 pupae 2d postWPP    351 pupae 3d postWPP    951 pupae 4d postWPP  1942 adult male 01day    1023 adult male 05day    968 adult male 30day    836 adult female 01day  (3900) adult female 05day  (5966) adult female 30day  (5649) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    7096 embryo 02-04hr    282 embryo 04-06hr    123 embryo 06-08hr    77 embryo 08-10hr    99 embryo 10-12hr    78 embryo 12-14hr    125 embryo 14-16hr    635 embryo 16-18hr    3372 embryo 18-20hr    5122 embryo 20-22hr    3504 embryo 22-24hr    3862 larva L1    1602 larva L2    1244 larva L3 12hr old    1036 larva L3 puffstage 1-2    1717 larva L3 puffstage 3-6    1332 larva L3 puffstage 7-9    2888 white prepupae new    6480 white prepupae 12hr    995 white prepupae 24hr    121 pupae 2d postWPP    351 pupae 3d postWPP    951 pupae 4d postWPP    1942 adult male 01day    1023 adult male 05day    968 adult male 30day    836 adult female 01day    3900 adult female 05day    5966 adult female 30day    5649 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    7096 embryo 02-04hr    282 embryo 04-06hr    123 embryo 06-08hr    77 embryo 08-10hr    99 embryo 10-12hr    78 embryo 12-14hr    125 embryo 14-16hr    635 embryo 16-18hr    3372 embryo 18-20hr    5122 embryo 20-22hr    3504 embryo 22-24hr    3862 larva L1    1602 larva L2    1244 larva L3 12hr old    1036 larva L3 puffstage 1-2    1717 larva L3 puffstage 3-6    1332 larva L3 puffstage 7-9    2888 white prepupae new    6480 white prepupae 12hr    995 white prepupae 24hr    121 pupae 2d postWPP    351 pupae 3d postWPP    951 pupae 4d postWPP    1942 adult male 01day    1023 adult male 05day    968 adult male 30day    836 adult female 01day    3900 adult female 05day    5966 adult female 30day    5649 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0037203    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0037203 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, larval/adult Malpighian tubules, adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult hindgut, larval salivary gland, larval trachea, adult testis, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0037203 expression level Tissue   Expression Level Larval Central Nervous System    2.075 Larval Midgut    764.4 Larval Hindgut    416.8 Larval Malpighian Tubules    2369.9 Larval Fat Body    2.8 Larval Salivary Gland    242.9 Larval Trachea    148.475 Larval Carcass    353.225 Adult Head    69.9 Adult Eye    45.575 Adult Brain    13.9 Adult Thoracic-Abdominal Ganglion    69.2 Adult Crop    69.2 Adult Midgut    1228.5 Adult Hindgut    491.9 Adult Malpighian Tubules    844.7 Adult Fat Body    16.7 Adult Salivary Gland    54.9 Adult Heart    6.775 Adult VirginFemale Spermatheca    50.5 Adult InseminatedFemale Spermatheca    82.6 Adult Ovary    813.2 Adult Testis    113 Adult Male Accessory Gland    43.1 Adult Carcass    81.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    2.075 Larval Midgut  (764.4) Larval Hindgut    416.8 Larval Malpighian Tubules  (2369.9) Larval Fat Body    2.8 Larval Salivary Gland    242.9 Larval Trachea    148.475 Larval Carcass    353.225 Adult Head    69.9 Adult Eye    45.575 Adult Brain    13.9 Adult Thoracic-Abdominal Ganglion    69.2 Adult Crop    69.2 Adult Midgut  (1228.5) Adult Hindgut    491.9 Adult Malpighian Tubules  (844.7) Adult Fat Body    16.7 Adult Salivary Gland    54.9 Adult Heart    6.775 Adult VirginFemale Spermatheca    50.5 Adult InseminatedFemale Spermatheca    82.6 Adult Ovary  (813.2) Adult Testis    113 Adult Male Accessory Gland    43.1 Adult Carcass    81.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    2.075 Larval Midgut    764.4 Larval Hindgut    416.8 Larval Malpighian Tubules  (2369.9) Larval Fat Body    2.8 Larval Salivary Gland    242.9 Larval Trachea    148.475 Larval Carcass    353.225 Adult Head    69.9 Adult Eye    45.575 Adult Brain    13.9 Adult Thoracic-Abdominal Ganglion    69.2 Adult Crop    69.2 Adult Midgut  (1228.5) Adult Hindgut    491.9 Adult Malpighian Tubules    844.7 Adult Fat Body    16.7 Adult Salivary Gland    54.9 Adult Heart    6.775 Adult VirginFemale Spermatheca    50.5 Adult InseminatedFemale Spermatheca    82.6 Adult Ovary    813.2 Adult Testis    113 Adult Male Accessory Gland    43.1 Adult Carcass    81.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2.075 Larval Midgut    764.4 Larval Hindgut    416.8 Larval Malpighian Tubules    2369.9 Larval Fat Body    2.8 Larval Salivary Gland    242.9 Larval Trachea    148.475 Larval Carcass    353.225 Adult Head    69.9 Adult Eye    45.575 Adult Brain    13.9 Adult Thoracic-Abdominal Ganglion    69.2 Adult Crop    69.2 Adult Midgut    1228.5 Adult Hindgut    491.9 Adult Malpighian Tubules    844.7 Adult Fat Body    16.7 Adult Salivary Gland    54.9 Adult Heart    6.775 Adult VirginFemale Spermatheca    50.5 Adult InseminatedFemale Spermatheca    82.6 Adult Ovary    813.2 Adult Testis    113 Adult Male Accessory Gland    43.1 Adult Carcass    81.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0037203 expression level Tissue   Expression Level Larval Central Nervous System    2.075 Larval Midgut    764.4 Larval Hindgut    416.8 Larval Malpighian Tubules    2369.9 Larval Fat Body    2.8 Larval Salivary Gland    242.9 Larval Trachea    148.475 Larval Carcass    353.225 Adult Head    69.9 Adult Eye    45.575 Adult Brain    13.9 Adult Thoracic-Abdominal Ganglion    69.2 Adult Crop    69.2 Adult Midgut    1228.5 Adult Hindgut    491.9 Adult Malpighian Tubules    844.7 Adult Fat Body    16.7 Adult Salivary Gland    54.9 Adult Heart    6.775 Adult VirginFemale Spermatheca    50.5 Adult InseminatedFemale Spermatheca    82.6 Adult Ovary    813.2 Adult Testis    113 Adult Male Accessory Gland    43.1 Adult Carcass    81.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    2.075 Larval Midgut  764.4 Larval Hindgut    416.8 Larval Malpighian Tubules  (2369.9) Larval Fat Body    2.8 Larval Salivary Gland    242.9 Larval Trachea    148.475 Larval Carcass    353.225 Adult Head    69.9 Adult Eye    45.575 Adult Brain    13.9 Adult Thoracic-Abdominal Ganglion    69.2 Adult Crop    69.2 Adult Midgut  (1228.5) Adult Hindgut    491.9 Adult Malpighian Tubules  (844.7) Adult Fat Body    16.7 Adult Salivary Gland    54.9 Adult Heart    6.775 Adult VirginFemale Spermatheca    50.5 Adult InseminatedFemale Spermatheca    82.6 Adult Ovary  813.2 Adult Testis    113 Adult Male Accessory Gland    43.1 Adult Carcass    81.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    2.075 Larval Midgut    764.4 Larval Hindgut    416.8 Larval Malpighian Tubules  (2369.9) Larval Fat Body    2.8 Larval Salivary Gland    242.9 Larval Trachea    148.475 Larval Carcass    353.225 Adult Head    69.9 Adult Eye    45.575 Adult Brain    13.9 Adult Thoracic-Abdominal Ganglion    69.2 Adult Crop    69.2 Adult Midgut  1228.5 Adult Hindgut    491.9 Adult Malpighian Tubules    844.7 Adult Fat Body    16.7 Adult Salivary Gland    54.9 Adult Heart    6.775 Adult VirginFemale Spermatheca    50.5 Adult InseminatedFemale Spermatheca    82.6 Adult Ovary    813.2 Adult Testis    113 Adult Male Accessory Gland    43.1 Adult Carcass    81.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2.075 Larval Midgut    764.4 Larval Hindgut    416.8 Larval Malpighian Tubules    2369.9 Larval Fat Body    2.8 Larval Salivary Gland    242.9 Larval Trachea    148.475 Larval Carcass    353.225 Adult Head    69.9 Adult Eye    45.575 Adult Brain    13.9 Adult Thoracic-Abdominal Ganglion    69.2 Adult Crop    69.2 Adult Midgut    1228.5 Adult Hindgut    491.9 Adult Malpighian Tubules    844.7 Adult Fat Body    16.7 Adult Salivary Gland    54.9 Adult Heart    6.775 Adult VirginFemale Spermatheca    50.5 Adult InseminatedFemale Spermatheca    82.6 Adult Ovary    813.2 Adult Testis    113 Adult Male Accessory Gland    43.1 Adult Carcass    81.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    69.9   NA  Eye    45.575   NA  Brain    13.9   2.075  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    69.2   NA  Crop    69.2   764.4  Midgut    1228.5   416.8  Hindgut    491.9   2369.9  Malpighian Tubules    844.7   2.8  Fat Body    16.7   242.9  Salivary Gland    54.9   NA  Heart    6.775   148.475  Trachea    NA   NA  VirginFemale Spermatheca    50.5   NA  InseminatedFemale Spermatheca    82.6   NA  Ovary    813.2   NA  Testis    113   NA  Male Accessory Gland    43.1   353.225  Carcass    81.5 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_10
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037203 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11128-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for slif Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | larval stage | partially, with Scer\GAL4Bx-MS1096 slifUY681 lethal | partially slif1 viable slifEY03570 viable, with Scer\GAL4pnr-MD237 slifGD12619 Sterility Allele fertile slifEY03570 Other Phenotypes Allele decreased cell number slif1 decreased cell number, with Scer\GAL4Bx-MS1096 slifUY681 decreased cell number (with Df(3L)Δ1AK), with Scer\GAL4Bx-MS1096 slifUY681 decreased cell size slif1 decreased cell size, with Scer\GAL4Bx-MS1096 slifUY681 decreased cell size, with Scer\GAL4nub-AC-62 slifScer\UAS.cCa decreased cell size, with Scer\GAL4ppl.PP slifUY681 decreased cell size (with Df(3L)Δ1AK), with Scer\GAL4Bx-MS1096 slifUY681 developmental rate defective, with Scer\GAL4ppl.PP slifUY681 increased cell number, with Scer\GAL4nub-AC-62 slifScer\UAS.cCa visible slif1 Phenotype manifest in Allele embryonic/larval fat body slif1 embryonic/larval fat body, with Scer\GAL4Bx-MS1096 slifUY681 embryonic/larval fat body, with Scer\GAL4ppl.PP slifUY681 embryonic/larval neuroblast, with Scer\GAL4Cg.PA slifUY681 larva, with Scer\GAL4ppl.PP slifUY681 lipid droplet & larval fat body, with Scer\GAL4ppl.PP slifUY681 lipid droplet & larval oenocyte, with Scer\GAL4Lsp2.PH slifUY681 lipid droplet & larval oenocyte, with Scer\GAL4ppl.PP slifUY681 wing, with Scer\GAL4Bx-MS1096 slifUY681 wing, with Scer\GAL4nub-AC-62 slifScer\UAS.cCa wing (with Df(3L)Δ1AK), with Scer\GAL4Bx-MS1096 slifUY681 wing | posterior compartment, with Scer\GAL4en-e16E slifUY681
Classical Alleles ( 11 )
For All Classical Alleles Show
Allele of slif Class Mutagen Stocks Known lesion slife03156 piggyBac transposase 1 -- slifEY03570 P-element activity 1 -- sliff00541 piggyBac transposase 1 -- sliff01640 piggyBac transposase 1 -- sliff03828 piggyBac transposase 1 -- sliff06219 piggyBac transposase 1 -- slifKG02761 P-element activity 1 -- slifMI01305 1 -- slif1 hypomorphic allele - genetic evidence P-element activity 0 Yes sliff05272 piggyBac transposase 0 -- slifUY681 P-element activity 0 Yes
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of slif Class Mutagen Stocks Known lesion slifGD12619 in vitro construct - RNAi in vitro construct - regulatory fusion 5 Yes slifKK101643 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes slifScer\UAS.cCa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6139 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD12619} NA P{KK101643} NA P{UAS-slif.C} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}slifEY03570 NA P{Mae-UAS.6.11}slifUY681 NA miscellaneous insertions Mi{MIC}slifMI01305 NA P{SUPor-P}slifKG02761 NA PBac{RB}slife03156 NA PBac{WH}sliff00541 NA PBac{WH}sliff01640 NA PBac{WH}sliff03828 NA PBac{WH}sliff05272 NA PBac{WH}sliff06219 NA
Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function
CV term Evidence References
cationic amino acid transmembrane transporter activity inferred from direct assay (Colombani et al., 2003)
Biological Process
CV term Evidence References
amino acid transport inferred from direct assay (Colombani et al., 2003) growth inferred from mutant phenotype (Colombani et al., 2003) lipid metabolic process inferred from mutant phenotype (Gutierrez et al., 2007)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
cationic amino acid transmembrane transporter activity inferred from sequence or structural similarity with EMBL:AB000113 (FlyBase, 1992-)
Biological Process
CV term Evidence References
amino acid transmembrane transport inferred from electronic annotation with InterPro:IPR002293 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
membrane inferred from electronic annotation with InterPro:IPR002293, InterPro:IPR004841 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions slif allele Gene References unspecified S6k (Colombani et al., 2003)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 65738 DroID - A comprehensive database of gene and protein interactions. • FBgn0037203 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40510
Orthologs
Genome-wide drosophilid orthologs	Dana\GF11006 Dere\GG16286 Dgri\GH16777 Dmoj\GI13437 Dper\GL24975 Dpse\GA10777 Dsec\GM22479 Dsim\GD15059 Dvir\GJ11799 Dwil\GK12893 Dyak\GE22647
Curated drosophilid orthologs	Dpse\GA10777
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL012131-PA Aedes aegypti (mosquito) XP_393144.2 Apis mellifera (honey bee) XP_001943215.1 Acyrthosiphon pisum (pea aphid) At1g58030.1 Arabidopsis thaliana (wall cress) At5g36940.1 Arabidopsis thaliana (wall cress) BGIBMGA014265-PA Bombyx mori (silk worm) ENSBTAP00000009736 Bos taurus (bovine) ENSBTAP00000013304 Bos taurus (bovine) ENSCAFP00000009958 Canis familiaris (dog) ENSCINP00000016860 Ciona intestinalis (sea squirt) CPIJ004244 Culex pipens (mosquito) ENSCPOP00000004502 Cavia porcellus (guinea pig) ENSCSAVP00000018882 Ciona savignyi (sedentary tunicate) 119893 Capitella spl (polychaete worm) DEHA2C07194g Debaryomyces Hansenii (yeast) DEHA2D10164g Debaryomyces Hansenii (yeast) DEHA2G06930g Debaryomyces Hansenii (yeast) 21886 Daphnia pulex (daphnia) ENSDARP00000027285 Danio rerio (zebra fish) ENSDARP00000053920 Danio rerio (zebra fish) ENSECAP00000014803 Equus caballus (horse) ENSECAP00000018304 Equus caballus (horse) ENSGACP00000024588 Gymnopilus aculeatus (mushroom) ENSGACP00000027024 Gymnopilus aculeatus (mushroom) ENSGALP00000022132 Gallus gallus (chicken) ENSGALP00000027546 Gallus gallus (chicken) ENSP00000298085 Homo sapiens (human) ENSP00000381162 Homo sapiens (human) 207718 Lottia gigantea (owl limpet) ENSMODP00000023784 Monodelphis domestica (gray opossum) ENSMMUP00000004365 Macaca mulatta (rhesus monkey) ENSMUSP00000098914 Mus musculus (house mouse) ENSMUSP00000112848 Mus musculus (house mouse) XP_001599622.1 Nasonia vitripennis (wasp) ENSORLP00000002300 Oryzias latipes (japanese killifish) PHUM002483-PA Pediculus humanus (human body louse) 195090 Physcomitrella patens (moss) ENSPPYP00000020601 Pongo pygmaeus (orangutan) ENSPPYP00000022884 Pongo pygmaeus (orangutan) 73775 Phytophthora ramorum (sudden oak death pathogen) 74514 Phytophthora ramorum (sudden oak death pathogen) ENSPTRP00000037822 Pan troglodytes (chimpanzee) ENSPTRP00000058257 Pan troglodytes (chimpanzee) ENSRNOP00000005580 Rattus norvegicus (norway rat) Smp_123010 Schistosoma mansoni (trematode parasite) ENSTNIP00000006839 Tetraodon nigroviridis (green spotted pufferfish) ENSTNIP00000021393 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000024975 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000001508 Xenopus tropicalis (frog) ENSXETP00000012149 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16188 PB16136 NV14736 NV13071 LH22022 LH12669 LH11005 FBgn0239861 FBgn0239460 FBgn0239337 FBgn0222575 FBgn0222404 FBgn0214902 FBgn0201071 FBgn0199053 FBgn0199054 FBgn0186731 FBgn0186217 FBgn0184098 FBgn0180379 FBgn0179161 FBgn0177349 JGI_V11_46947 JGI_V11_21886 JGI_V11_236331 FBgn0080209 FBgn0078953 FBgn0070833 FBgn0162562 FBgn0162380 FBgn0160332 FBgn0136193 FBgn0135862 FBgn0036764 FBgn0036493 FBgn0124248 FBgn0122008 FBgn0108520 FBgn0108127 FBgn0108013 FBgn0102222 FBgn0100688 FBgn0088046 CPIJ004245 CPIJ004246 CPIJ004244 BGIBMGA014266 BGIBMGA014265 BGIBMGA014238 ACYPI008904 ACYPI008323 ACYPI005472 ACYPI005156 ACYPI005118 ACYPI003923 ACYPI003523 ACYPI003240 ACYPI002633 ACYPI001640 ACYPI000584 ACYPI000537 GB15921 GB14909 AGAP010563 AGAP010561 AAEL012131 AAEL012128 AAEL010988 AAEL009362 PHUM169840 PHUM258130 GLEAN_01941
Stocks & Reagents
Stocks Listed in FlyBase ( 13 )
Bloomington	34177 y1 w*; Mi{MIC}slifMI01305 19906 y1 w67c23; P{EPgy2}slifEY03570
Harvard	- PBac{RB}slife03156 - PBac{WH}sliff00541 - PBac{WH}sliff01640 - PBac{WH}sliff03828 - PBac{WH}sliff06219
VDRC	v26786 w1118 P{GD12619}v26786 v45587 w1118; P{GD12619}v45587 v45588 w1118; P{GD12619}v45588 v45589 w1118; P{GD12619}v45589 v45590 w1118; P{GD12619}v45590
	More stocks available...
Genomic Clones ( 1 )
	BACR48E05 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 64 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD37241
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH14268 GM20137 LD26994 LD35820 LP09774 LP11987 LP12075 RE35681 RE42394 RE44627 RE60001 RE60556 RH04970 RH23267 RH35774 RH48906
Other clones	34537 105913 124347 214445.44 CK01.52A.F2 CK01.86A.A6 CK01.92B.F8 Dmel_neb_003475_0632_3618 Dmel_neb_009902_0854_1000 EC25422 EK042253 EK068035 EK072156 EK246859 EK267307 EP21962 RH45501 RP01101 RP01406 RP001003147 RP001014263 RP001024407 RP001032774 RP003016135 RP003028072 RP003028096 RP003062302 RP003099441 RP003128782 RP003164275 RP003211162 RP003213773 RP003252356 RP003275699 RP003289822 RP003299216 RP003303057 RP003346640 RP003451120 RP003497933 RP003551448 RP003606243 RP003612560 RP003632142 RP003643242 RP003644894 RP003662944
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0037203 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40510
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: slif CG11128 (Leopold, 2003.3.18)
Source for database merge of
Additional comments
Other Comments
	The localisation and levels of slif are sensitive to Tor activity, with high levels of Tor signaling resulting in accumulation of slif near the cell surface, and decreased Tor signaling leading to slif down-regulation. (Hennig et al., 2006) Identification: in a screen for growth modifiers. (Colombani et al., 2003) Disruption of slif function in the fat body results in a developmental growth defect similar to that seen under amino acid deprivation. (Colombani et al., 2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_141171 NM_168977 NM_168978 RefSeq (Proteins) • NP_649428 NP_730764 NP_730765 DDBJ / EMBL / GenBank • AAF51880 AAF51881 AAF51882 AAM11177 AI457030 AW943378 AY094824 BH740790 BI615757 CL632140 CZ480920 CZ483003 CZ484106 CZ484107 CZ486422 CZ487905 CZ487906 CZ488881 Entrez Gene - A searchable database of RefSeq genes. • 40510 UniProtKB/TrEMBL • Q9VNP7
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Cationic amino acid transporter (IPR015606) Amino acid/polyamine transporter I (IPR002293) Amino acid permease domain (IPR004841)
Linkouts
	BioGRID - A database of protein and genetic interactions • 65738 DroID - A comprehensive database of gene and protein interactions. • FBgn0037203 DRSC - Results from RNAi screens. • FBgn0037203 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037203 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11128-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0037203 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40510 InParanoid A subset of ortholog calls from InParanoid. • AAEL012131-PA Aedes aegypti (mosquito) XP_393144.2 Apis mellifera (honey bee) XP_001943215.1 Acyrthosiphon pisum (pea aphid) At1g58030.1 Arabidopsis thaliana (wall cress) At5g36940.1 Arabidopsis thaliana (wall cress) BGIBMGA014265-PA Bombyx mori (silk worm) ENSBTAP00000009736 Bos taurus (bovine) ENSBTAP00000013304 Bos taurus (bovine) ENSCAFP00000009958 Canis familiaris (dog) ENSCINP00000016860 Ciona intestinalis (sea squirt) CPIJ004244 Culex pipens (mosquito) ENSCPOP00000004502 Cavia porcellus (guinea pig) ENSCSAVP00000018882 Ciona savignyi (sedentary tunicate) 119893 Capitella spl (polychaete worm) DEHA2C07194g Debaryomyces Hansenii (yeast) DEHA2D10164g Debaryomyces Hansenii (yeast) DEHA2G06930g Debaryomyces Hansenii (yeast) 21886 Daphnia pulex (daphnia) ENSDARP00000027285 Danio rerio (zebra fish) ENSDARP00000053920 Danio rerio (zebra fish) ENSECAP00000014803 Equus caballus (horse) ENSECAP00000018304 Equus caballus (horse) ENSGACP00000024588 Gymnopilus aculeatus (mushroom) ENSGACP00000027024 Gymnopilus aculeatus (mushroom) ENSGALP00000022132 Gallus gallus (chicken) ENSGALP00000027546 Gallus gallus (chicken) ENSP00000298085 Homo sapiens (human) ENSP00000381162 Homo sapiens (human) 207718 Lottia gigantea (owl limpet) ENSMODP00000023784 Monodelphis domestica (gray opossum) ENSMMUP00000004365 Macaca mulatta (rhesus monkey) ENSMUSP00000098914 Mus musculus (house mouse) ENSMUSP00000112848 Mus musculus (house mouse) XP_001599622.1 Nasonia vitripennis (wasp) ENSORLP00000002300 Oryzias latipes (japanese killifish) PHUM002483-PA Pediculus humanus (human body louse) 195090 Physcomitrella patens (moss) ENSPPYP00000020601 Pongo pygmaeus (orangutan) ENSPPYP00000022884 Pongo pygmaeus (orangutan) 73775 Phytophthora ramorum (sudden oak death pathogen) 74514 Phytophthora ramorum (sudden oak death pathogen) ENSPTRP00000037822 Pan troglodytes (chimpanzee) ENSPTRP00000058257 Pan troglodytes (chimpanzee) ENSRNOP00000005580 Rattus norvegicus (norway rat) Smp_123010 Schistosoma mansoni (trematode parasite) ENSTNIP00000006839 Tetraodon nigroviridis (green spotted pufferfish) ENSTNIP00000021393 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000024975 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000001508 Xenopus tropicalis (frog) ENSXETP00000012149 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40510 modMine - Data generated by the modENCODE project. • FBgn0037203 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16188 PB16136 NV14736 NV13071 LH22022 LH12669 LH11005 FBgn0239861 FBgn0239460 FBgn0239337 FBgn0222575 FBgn0222404 FBgn0214902 FBgn0201071 FBgn0199053 FBgn0199054 FBgn0186731 FBgn0186217 FBgn0184098 FBgn0180379 FBgn0179161 FBgn0177349 JGI_V11_46947 JGI_V11_21886 JGI_V11_236331 FBgn0080209 FBgn0078953 FBgn0070833 FBgn0162562 FBgn0162380 FBgn0160332 FBgn0136193 FBgn0135862 FBgn0036764 FBgn0036493 FBgn0124248 FBgn0122008 FBgn0108520 FBgn0108127 FBgn0108013 FBgn0102222 FBgn0100688 FBgn0088046 CPIJ004245 CPIJ004246 CPIJ004244 BGIBMGA014266 BGIBMGA014265 BGIBMGA014238 ACYPI008904 ACYPI008323 ACYPI005472 ACYPI005156 ACYPI005118 ACYPI003923 ACYPI003523 ACYPI003240 ACYPI002633 ACYPI001640 ACYPI000584 ACYPI000537 GB15921 GB14909 AGAP010563 AGAP010561 AAEL012131 AAEL012128 AAEL010988 AAEL009362 PHUM169840 PHUM258130 GLEAN_01941
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	CG11128 (Raisin et al., 2003, Corradini et al., 2003, Giot et al., 2003, Romero-Calderon et al., 2007, Keleman et al., 2009.8.5) slif (Bourouis et al., 2007, Goberdhan et al., 2005, Colombani et al., 2003, Gutierrez et al., 2007, Lawniczak and Begun, 2004, Arancio et al., 2010, Romero-Calderon et al., 2007, Hennig et al., 2006, Colombani et al., 2003, Hall et al., 2007, Sousa-Nunes et al., 2011, Resnik-Docampo and de Celis, 2011) Slif (Nuzhdin et al., 2009, Arquier et al., 2008, Cronin et al., 2009)
Name Synonym	slimfast (Colombani et al., 2003, Gutierrez et al., 2007, Hall et al., 2007) Slimfast (Hennig et al., 2006)
Secondary FlyBase IDs
References ( 42 )
Generate a list of	All references relating to this gene ( 42 )
List References by type	Research paper  ( 17 ) Supplementary material  ( 4 ) Review  ( 2 ) Personal communication to FlyBase  ( 6 ) Abstract  ( 6 ) FlyBase analysis  ( 1 ) Computer file  ( 3 ) Automatic genome annotation  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 4 )
	Cheng et al., 2011, Cell 146(3): 435--447 Anaplastic Lymphoma Kinase Spares Organ Growth during Nutrient Restriction in Drosophila. [FBrf0214599] Resnik-Docampo and de Celis, 2011, PLoS ONE 6(1): e14528 MAP4K3 Is a Component of the TORC1 Signalling Complex that Modulates Cell Growth and Viability in Drosophila melanogaster. [FBrf0212911] Sousa-Nunes et al., 2011, Nature 471(7339): 508--512 Fat cells reactivate quiescent neuroblasts via TOR and glial insulin relays in Drosophila. [FBrf0214426] Arancio et al., 2010, Genetics 185(1): 129--140 The nucleosome remodeling factor ISWI functionally interacts with an evolutionarily conserved network of cellular factors. [FBrf0213976] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...