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Gene Dmel\CG12581

General Information
Symbol	Dmel\CG12581	Species	D. melanogaster
Name		Annotation symbol	CG12581
Feature type	protein_coding_gene	FlyBase ID	FBgn0037213
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	81F5-81F6	Sequence location	3R:380..10,200 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG12581 (FBgn0037213). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has 2 annotated transcripts and 2 annotated polypeptides. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult crop, larval trachea. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult hindgut, larval fat body, adult salivary gland, adult spermathecae, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1633280_s_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG12581. Gene sequence location is 3R:380..10200.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN31551 HFA12207 HFA12206
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 81F5-81F6   Limits computationally determined from genome sequence between P{PZ}l(3)0273302733 and P{EP}EP974
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG12581 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	EST data suggest additional 3' exon(s)
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG12581-RA FBtr0078962  NM_141178   3162   665 CG12581-RB FBtr0078961  NM_164313   3094   665
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG12581-PA   FBpp0078602   70.8   665   10.25     NP_649435   AAF52174 CG12581-PB   FBpp0078601   70.8   665   10.25     NP_730781   AAN13329
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA140909   AA141238   AA695505   AA697774   AA697780   AA804076   AA941257   AE014297 AAF52174   AE014297 AAN13329   AI257275   AW941182   AW942727   AY059451 AAL13357   AY070849 AAL48471   BG637665   BI168800   BI171397   BI173298   BI173300   BI216142   BI227752   BI228396   BI237988   BI243762   BI357424   BI485495   BI575146   BI586370   BT056255   CK657559   CK661177   CK662380   CO189415   CO272273   CO276164   CO278417   CO281188   CO288805   CO289336   CO291654   CO294498   CO312417   CO312658   CO313334   CO318274   CO319106   CO319107   CO328792   EC058858   EC061753   EC064841   EC068612   EC080717   EC081676   EC083674   EC090095   EC090837   EC197872   EC200798   EC201012   EC202456   EC207164   EC216805   EC219035   EC225634   EC231997   EC235836   EC241987   EC244480   EC250101   EC250334   EC250335   GH738799   GH738806   GH739183   GH741953   GH743192   GH743695   GH744118   GH744689   GH745434   GH745794   GH763114   GH767366   GH767481   GH767863   GH768694   GH768703   GO254559
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8T953 Q95TE1 Q9VMY3
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0037213    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0037213 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0037213 expression level Developmental Stage   Expression Level embryo 00-02hr    332 embryo 02-04hr    4713 embryo 04-06hr    8742 embryo 06-08hr    7311 embryo 08-10hr    6284 embryo 10-12hr    8064 embryo 12-14hr    5741 embryo 14-16hr    6461 embryo 16-18hr    4436 embryo 18-20hr    4167 embryo 20-22hr    2318 embryo 22-24hr    2292 larva L1    2827 larva L2    3406 larva L3 12hr old    2142 larva L3 puffstage 1-2    1357 larva L3 puffstage 3-6    2142 larva L3 puffstage 7-9    2518 white prepupae new    2738 white prepupae 12hr    3454 white prepupae 24hr    4105 pupae 2d postWPP    3761 pupae 3d postWPP    3196 pupae 4d postWPP    4709 adult male 01day    1989 adult male 05day    1750 adult male 30day    1731 adult female 01day    1972 adult female 05day    907 adult female 30day    865 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (332) embryo 02-04hr  (4713) embryo 04-06hr  (8742) embryo 06-08hr  (7311) embryo 08-10hr  (6284) embryo 10-12hr  (8064) embryo 12-14hr  (5741) embryo 14-16hr  (6461) embryo 16-18hr  (4436) embryo 18-20hr  (4167) embryo 20-22hr  (2318) embryo 22-24hr  (2292) larva L1  (2827) larva L2  (3406) larva L3 12hr old  (2142) larva L3 puffstage 1-2  (1357) larva L3 puffstage 3-6  (2142) larva L3 puffstage 7-9  (2518) white prepupae new  (2738) white prepupae 12hr  (3454) white prepupae 24hr  (4105) pupae 2d postWPP  (3761) pupae 3d postWPP  (3196) pupae 4d postWPP  (4709) adult male 01day  (1989) adult male 05day  (1750) adult male 30day  (1731) adult female 01day  (1972) adult female 05day  (907) adult female 30day  (865) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    332 embryo 02-04hr  (4713) embryo 04-06hr  (8742) embryo 06-08hr  (7311) embryo 08-10hr  (6284) embryo 10-12hr  (8064) embryo 12-14hr  (5741) embryo 14-16hr  (6461) embryo 16-18hr  (4436) embryo 18-20hr  (4167) embryo 20-22hr  (2318) embryo 22-24hr  (2292) larva L1  (2827) larva L2  (3406) larva L3 12hr old  (2142) larva L3 puffstage 1-2    1357 larva L3 puffstage 3-6  (2142) larva L3 puffstage 7-9  (2518) white prepupae new  (2738) white prepupae 12hr  (3454) white prepupae 24hr  (4105) pupae 2d postWPP  (3761) pupae 3d postWPP  (3196) pupae 4d postWPP  (4709) adult male 01day  (1989) adult male 05day  (1750) adult male 30day  (1731) adult female 01day  (1972) adult female 05day    907 adult female 30day    865 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    332 embryo 02-04hr    4713 embryo 04-06hr    8742 embryo 06-08hr    7311 embryo 08-10hr    6284 embryo 10-12hr    8064 embryo 12-14hr    5741 embryo 14-16hr    6461 embryo 16-18hr    4436 embryo 18-20hr    4167 embryo 20-22hr    2318 embryo 22-24hr    2292 larva L1    2827 larva L2    3406 larva L3 12hr old    2142 larva L3 puffstage 1-2    1357 larva L3 puffstage 3-6    2142 larva L3 puffstage 7-9    2518 white prepupae new    2738 white prepupae 12hr    3454 white prepupae 24hr    4105 pupae 2d postWPP    3761 pupae 3d postWPP    3196 pupae 4d postWPP    4709 adult male 01day    1989 adult male 05day    1750 adult male 30day    1731 adult female 01day    1972 adult female 05day    907 adult female 30day    865 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    332 embryo 02-04hr    4713 embryo 04-06hr    8742 embryo 06-08hr    7311 embryo 08-10hr    6284 embryo 10-12hr    8064 embryo 12-14hr    5741 embryo 14-16hr    6461 embryo 16-18hr    4436 embryo 18-20hr    4167 embryo 20-22hr    2318 embryo 22-24hr    2292 larva L1    2827 larva L2    3406 larva L3 12hr old    2142 larva L3 puffstage 1-2    1357 larva L3 puffstage 3-6    2142 larva L3 puffstage 7-9    2518 white prepupae new    2738 white prepupae 12hr    3454 white prepupae 24hr    4105 pupae 2d postWPP    3761 pupae 3d postWPP    3196 pupae 4d postWPP    4709 adult male 01day    1989 adult male 05day    1750 adult male 30day    1731 adult female 01day    1972 adult female 05day    907 adult female 30day    865 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0037213 expression level Developmental Stage   Expression Level embryo 00-02hr    332 embryo 02-04hr    4713 embryo 04-06hr    8742 embryo 06-08hr    7311 embryo 08-10hr    6284 embryo 10-12hr    8064 embryo 12-14hr    5741 embryo 14-16hr    6461 embryo 16-18hr    4436 embryo 18-20hr    4167 embryo 20-22hr    2318 embryo 22-24hr    2292 larva L1    2827 larva L2    3406 larva L3 12hr old    2142 larva L3 puffstage 1-2    1357 larva L3 puffstage 3-6    2142 larva L3 puffstage 7-9    2518 white prepupae new    2738 white prepupae 12hr    3454 white prepupae 24hr    4105 pupae 2d postWPP    3761 pupae 3d postWPP    3196 pupae 4d postWPP    4709 adult male 01day    1989 adult male 05day    1750 adult male 30day    1731 adult female 01day    1972 adult female 05day    907 adult female 30day    865 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (332) embryo 02-04hr  (4713) embryo 04-06hr  (8742) embryo 06-08hr  (7311) embryo 08-10hr  (6284) embryo 10-12hr  (8064) embryo 12-14hr  (5741) embryo 14-16hr  (6461) embryo 16-18hr  (4436) embryo 18-20hr  (4167) embryo 20-22hr  (2318) embryo 22-24hr  (2292) larva L1  (2827) larva L2  (3406) larva L3 12hr old  (2142) larva L3 puffstage 1-2  (1357) larva L3 puffstage 3-6  (2142) larva L3 puffstage 7-9  (2518) white prepupae new  (2738) white prepupae 12hr  (3454) white prepupae 24hr  (4105) pupae 2d postWPP  (3761) pupae 3d postWPP  (3196) pupae 4d postWPP  (4709) adult male 01day  (1989) adult male 05day  (1750) adult male 30day  (1731) adult female 01day  (1972) adult female 05day  (907) adult female 30day  (865) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    332 embryo 02-04hr  (4713) embryo 04-06hr  (8742) embryo 06-08hr  (7311) embryo 08-10hr  (6284) embryo 10-12hr  (8064) embryo 12-14hr  (5741) embryo 14-16hr  (6461) embryo 16-18hr  (4436) embryo 18-20hr  (4167) embryo 20-22hr  2318 embryo 22-24hr  2292 larva L1  (2827) larva L2  (3406) larva L3 12hr old  2142 larva L3 puffstage 1-2    1357 larva L3 puffstage 3-6  2142 larva L3 puffstage 7-9  (2518) white prepupae new  (2738) white prepupae 12hr  (3454) white prepupae 24hr  (4105) pupae 2d postWPP  (3761) pupae 3d postWPP  (3196) pupae 4d postWPP  (4709) adult male 01day  1989 adult male 05day  1750 adult male 30day  1731 adult female 01day  1972 adult female 05day    907 adult female 30day    865 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    332 embryo 02-04hr    4713 embryo 04-06hr    8742 embryo 06-08hr    7311 embryo 08-10hr    6284 embryo 10-12hr    8064 embryo 12-14hr    5741 embryo 14-16hr    6461 embryo 16-18hr    4436 embryo 18-20hr    4167 embryo 20-22hr    2318 embryo 22-24hr    2292 larva L1    2827 larva L2    3406 larva L3 12hr old    2142 larva L3 puffstage 1-2    1357 larva L3 puffstage 3-6    2142 larva L3 puffstage 7-9    2518 white prepupae new    2738 white prepupae 12hr    3454 white prepupae 24hr    4105 pupae 2d postWPP    3761 pupae 3d postWPP    3196 pupae 4d postWPP    4709 adult male 01day    1989 adult male 05day    1750 adult male 30day    1731 adult female 01day    1972 adult female 05day    907 adult female 30day    865 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    332 embryo 02-04hr    4713 embryo 04-06hr    8742 embryo 06-08hr    7311 embryo 08-10hr    6284 embryo 10-12hr    8064 embryo 12-14hr    5741 embryo 14-16hr    6461 embryo 16-18hr    4436 embryo 18-20hr    4167 embryo 20-22hr    2318 embryo 22-24hr    2292 larva L1    2827 larva L2    3406 larva L3 12hr old    2142 larva L3 puffstage 1-2    1357 larva L3 puffstage 3-6    2142 larva L3 puffstage 7-9    2518 white prepupae new    2738 white prepupae 12hr    3454 white prepupae 24hr    4105 pupae 2d postWPP    3761 pupae 3d postWPP    3196 pupae 4d postWPP    4709 adult male 01day    1989 adult male 05day    1750 adult male 30day    1731 adult female 01day    1972 adult female 05day    907 adult female 30day    865 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0037213    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0037213 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult crop, larval trachea. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult hindgut, larval fat body, adult salivary gland, adult spermathecae, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0037213 expression level Tissue   Expression Level Larval Central Nervous System    81.35 Larval Midgut    29 Larval Hindgut    316.7 Larval Malpighian Tubules    50.9 Larval Fat Body    169.5 Larval Salivary Gland    81.7 Larval Trachea    522.5 Larval Carcass    227.05 Adult Head    222 Adult Eye    169 Adult Brain    13.9 Adult Thoracic-Abdominal Ganglion    9.5 Adult Crop    900.8 Adult Midgut no informative data Adult Hindgut    417.7 Adult Malpighian Tubules no informative data Adult Fat Body    49.7 Adult Salivary Gland    135 Adult Heart    28.1 Adult VirginFemale Spermatheca    189.2 Adult InseminatedFemale Spermatheca    218.4 Adult Ovary    37.6 Adult Testis    8.3 Adult Male Accessory Gland    420.4 Adult Carcass    260.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    81.35 Larval Midgut    29 Larval Hindgut    316.7 Larval Malpighian Tubules    50.9 Larval Fat Body    169.5 Larval Salivary Gland    81.7 Larval Trachea  522.5 Larval Carcass    227.05 Adult Head    222 Adult Eye    169 Adult Brain    13.9 Adult Thoracic-Abdominal Ganglion    9.5 Adult Crop  (900.8) Adult Midgut no informative data Adult Hindgut    417.7 Adult Malpighian Tubules no informative data Adult Fat Body    49.7 Adult Salivary Gland    135 Adult Heart    28.1 Adult VirginFemale Spermatheca    189.2 Adult InseminatedFemale Spermatheca    218.4 Adult Ovary    37.6 Adult Testis    8.3 Adult Male Accessory Gland    420.4 Adult Carcass    260.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    81.35 Larval Midgut    29 Larval Hindgut    316.7 Larval Malpighian Tubules    50.9 Larval Fat Body    169.5 Larval Salivary Gland    81.7 Larval Trachea    522.5 Larval Carcass    227.05 Adult Head    222 Adult Eye    169 Adult Brain    13.9 Adult Thoracic-Abdominal Ganglion    9.5 Adult Crop    900.8 Adult Midgut no informative data Adult Hindgut    417.7 Adult Malpighian Tubules no informative data Adult Fat Body    49.7 Adult Salivary Gland    135 Adult Heart    28.1 Adult VirginFemale Spermatheca    189.2 Adult InseminatedFemale Spermatheca    218.4 Adult Ovary    37.6 Adult Testis    8.3 Adult Male Accessory Gland    420.4 Adult Carcass    260.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    81.35 Larval Midgut    29 Larval Hindgut    316.7 Larval Malpighian Tubules    50.9 Larval Fat Body    169.5 Larval Salivary Gland    81.7 Larval Trachea    522.5 Larval Carcass    227.05 Adult Head    222 Adult Eye    169 Adult Brain    13.9 Adult Thoracic-Abdominal Ganglion    9.5 Adult Crop    900.8 Adult Midgut no informative data Adult Hindgut    417.7 Adult Malpighian Tubules no informative data Adult Fat Body    49.7 Adult Salivary Gland    135 Adult Heart    28.1 Adult VirginFemale Spermatheca    189.2 Adult InseminatedFemale Spermatheca    218.4 Adult Ovary    37.6 Adult Testis    8.3 Adult Male Accessory Gland    420.4 Adult Carcass    260.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0037213 expression level Tissue   Expression Level Larval Central Nervous System    81.35 Larval Midgut    29 Larval Hindgut    316.7 Larval Malpighian Tubules    50.9 Larval Fat Body    169.5 Larval Salivary Gland    81.7 Larval Trachea    522.5 Larval Carcass    227.05 Adult Head    222 Adult Eye    169 Adult Brain    13.9 Adult Thoracic-Abdominal Ganglion    9.5 Adult Crop    900.8 Adult Midgut no informative data Adult Hindgut    417.7 Adult Malpighian Tubules no informative data Adult Fat Body    49.7 Adult Salivary Gland    135 Adult Heart    28.1 Adult VirginFemale Spermatheca    189.2 Adult InseminatedFemale Spermatheca    218.4 Adult Ovary    37.6 Adult Testis    8.3 Adult Male Accessory Gland    420.4 Adult Carcass    260.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    81.35 Larval Midgut    29 Larval Hindgut    316.7 Larval Malpighian Tubules    50.9 Larval Fat Body    169.5 Larval Salivary Gland    81.7 Larval Trachea  522.5 Larval Carcass    227.05 Adult Head    222 Adult Eye    169 Adult Brain    13.9 Adult Thoracic-Abdominal Ganglion    9.5 Adult Crop  (900.8) Adult Midgut no informative data Adult Hindgut    417.7 Adult Malpighian Tubules no informative data Adult Fat Body    49.7 Adult Salivary Gland    135 Adult Heart    28.1 Adult VirginFemale Spermatheca    189.2 Adult InseminatedFemale Spermatheca    218.4 Adult Ovary    37.6 Adult Testis    8.3 Adult Male Accessory Gland    420.4 Adult Carcass    260.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    81.35 Larval Midgut    29 Larval Hindgut    316.7 Larval Malpighian Tubules    50.9 Larval Fat Body    169.5 Larval Salivary Gland    81.7 Larval Trachea    522.5 Larval Carcass    227.05 Adult Head    222 Adult Eye    169 Adult Brain    13.9 Adult Thoracic-Abdominal Ganglion    9.5 Adult Crop    900.8 Adult Midgut no informative data Adult Hindgut    417.7 Adult Malpighian Tubules no informative data Adult Fat Body    49.7 Adult Salivary Gland    135 Adult Heart    28.1 Adult VirginFemale Spermatheca    189.2 Adult InseminatedFemale Spermatheca    218.4 Adult Ovary    37.6 Adult Testis    8.3 Adult Male Accessory Gland    420.4 Adult Carcass    260.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    81.35 Larval Midgut    29 Larval Hindgut    316.7 Larval Malpighian Tubules    50.9 Larval Fat Body    169.5 Larval Salivary Gland    81.7 Larval Trachea    522.5 Larval Carcass    227.05 Adult Head    222 Adult Eye    169 Adult Brain    13.9 Adult Thoracic-Abdominal Ganglion    9.5 Adult Crop    900.8 Adult Midgut no informative data Adult Hindgut    417.7 Adult Malpighian Tubules no informative data Adult Fat Body    49.7 Adult Salivary Gland    135 Adult Heart    28.1 Adult VirginFemale Spermatheca    189.2 Adult InseminatedFemale Spermatheca    218.4 Adult Ovary    37.6 Adult Testis    8.3 Adult Male Accessory Gland    420.4 Adult Carcass    260.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut no informative data Adult Hindgut     Adult Malpighian Tubules no informative data Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    222   NA  Eye    169   NA  Brain    13.9   81.35  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    9.5   NA  Crop    900.8   29  Midgut    no informative data   316.7  Hindgut    417.7   50.9  Malpighian Tubules    no informative data   169.5  Fat Body    49.7   81.7  Salivary Gland    135   NA  Heart    28.1   522.5  Trachea    NA   NA  VirginFemale Spermatheca    189.2   NA  InseminatedFemale Spermatheca    218.4   NA  Ovary    37.6   NA  Testis    8.3   NA  Male Accessory Gland    420.4   227.05  Carcass    260.7 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_11
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037213 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12581-RB FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG12581 Stages(s) 4-6 Stages(s) 9-10 Stages(s) 11-12
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele semi-lethal | pupal stage, with Scer\GAL4pnr-MD237 CG12581GD10251 viable, with Scer\GAL4pnr-MD237 CG12581GD7766 Other Phenotypes Allele body color defective, with Scer\GAL4pnr-MD237 CG12581GD7766 visible, with Scer\GAL4pnr-MD237 CG12581GD7766 CG12581GD10251 Phenotype manifest in Allele chaeta | supernumerary, with Scer\GAL4pnr-MD237 CG12581GD7766 mesothoracic tergum, with Scer\GAL4pnr-MD237 CG12581GD7766 trichogen cell, with Scer\GAL4pnr-MD237 CG12581GD10251
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG12581 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG12581 Class Mutagen Stocks Known lesion CG12581GD7766 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG12581GD10251 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG12581KK111551 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7766} NA P{GD10251} NA P{KK111551} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG12581 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 65746 DroID - A comprehensive database of gene and protein interactions. • FBgn0037213 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40522
Orthologs
Genome-wide drosophilid orthologs	Dana\GF17687 Dere\GG12154 Dgri\GH21328 Dmoj\GI10497 Dper\GL12301 Dpse\GA11701 Dsec\GM10732 Dvir\GJ23178 Dwil\GK12067 Dyak\GE25393
Curated drosophilid orthologs	Dpse\GA11701
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL000336-PA Aedes aegypti (mosquito) AGAP002200-PA Anopheles gambiae (mosquito) XP_396643.1 Apis mellifera (honey bee) XP_001946893.1 Acyrthosiphon pisum (pea aphid) CN18091 Caenorhabditis brenneri (small nematode) CBP12161 Caenorhabditis briggsae (nematode) CE31583 Caenorhabditis elegans (worm) JA10239 Caenorhabditis japonica (nematode) CPIJ011846 Culex pipens (mosquito) RP47685 Caenorhabditis remanei (nematode) 223172 Capitella spl (polychaete worm) 318494 Daphnia pulex (daphnia) 193651 Hypsipyla robusta (cedar shoot borer) ISCW007942-PA Ixodes scapularis (deer tick) 236174 Lottia gigantea (owl limpet) PHUM007781-PA Pediculus humanus (human body louse) PP20436 Pristionchus pacificus (nematode) XP_001810169.1 Tribolium castaneum (red flour beetle) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV50207 LH16427 ISCW007942 FBgn0242470 FBgn0214078 FBgn0210280 FBgn0165678 JGI_V11_318494 FBgn0071751 FBgn0149908 FBgn0133261 FBgn0128790 FBgn0104446 FBgn0094705 CPIJ011844 CPIJ011845 ACYPI005401 GB17667 AGAP002200 AAEL000336 PB19537 PHUM231560 GLEAN_14886
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
VDRC	v31979 w1118; P{GD7766}v31979 v31981 w1118; P{GD7766}v31981 v21331 w1118; P{GD10251}v21331
Genomic Clones ( 1 )
	BACR15O02 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 81 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GM02933
Other clones	FI04032
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	HL03143 LP05587 LP20388 LP22545 LP23959 RE09682 RE13159 RE16090 RE16092 RE23072 RE24974 RE25935 RE34328 RE41475 RE43909 RE68830 RH26312 RH28421
Other clones	8200 17795 21166 38893 65524 70217 75105 101946 104381 106760 166644 174971 174973 181489 283411 283439 CK01.19C.F6 CK01.54C.G1 CK01.64A.G8 CK01.84C.F8 CK01.88A.D5 CK01.90A.C5 CK01.94A.F6 CK01.145D.C2 CK00553 CK01436 EK044225 EK069415 EK070811 EK106517 EK119841 EK130024 EK156143 EK197914 EK207060 EK228716 EK229609 EK232148 EK271223 EK276247 EK276251 EK291424 GM12753 HL03135 RP01059 RP01108 RP01140 RP001004945 RP001004950 RP001011303 RP001016238 RP001024406 RP001026925 RP001030330 RP001030539 RP001033015 RP001039606 RP001047528 RP001047837 RP001050736 RP001051319
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0037213 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40522
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_141178 NM_164313 RefSeq (Proteins) • NP_649435 NP_730781 DDBJ / EMBL / GenBank • AA695505 AA804076 AA941257 AAF52174 AAL13357 AAL48471 AAN13329 AW941182 AW942727 AY059451 AY070849 Entrez Gene - A searchable database of RefSeq genes. • 40522 UniProtKB/TrEMBL • Q8T953 Q9VMY3 Q95TE1
Other Crossreferences
Linkouts
	BioGRID - A database of protein and genetic interactions • 65746 DroID - A comprehensive database of gene and protein interactions. • FBgn0037213 DRSC - Results from RNAi screens. • FBgn0037213 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037213 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12581-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0037213 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40522 InParanoid A subset of ortholog calls from InParanoid. • AAEL000336-PA Aedes aegypti (mosquito) AGAP002200-PA Anopheles gambiae (mosquito) XP_396643.1 Apis mellifera (honey bee) XP_001946893.1 Acyrthosiphon pisum (pea aphid) CN18091 Caenorhabditis brenneri (small nematode) CBP12161 Caenorhabditis briggsae (nematode) CE31583 Caenorhabditis elegans (worm) JA10239 Caenorhabditis japonica (nematode) CPIJ011846 Culex pipens (mosquito) RP47685 Caenorhabditis remanei (nematode) 223172 Capitella spl (polychaete worm) 318494 Daphnia pulex (daphnia) 193651 Hypsipyla robusta (cedar shoot borer) ISCW007942-PA Ixodes scapularis (deer tick) 236174 Lottia gigantea (owl limpet) PHUM007781-PA Pediculus humanus (human body louse) PP20436 Pristionchus pacificus (nematode) XP_001810169.1 Tribolium castaneum (red flour beetle) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40522 modMine - Data generated by the modENCODE project. • FBgn0037213 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV50207 LH16427 ISCW007942 FBgn0242470 FBgn0214078 FBgn0210280 FBgn0165678 JGI_V11_318494 FBgn0071751 FBgn0149908 FBgn0133261 FBgn0128790 FBgn0104446 FBgn0094705 CPIJ011844 CPIJ011845 ACYPI005401 GB17667 AGAP002200 AAEL000336 PB19537 PHUM231560 GLEAN_14886
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG12581 (Bochdanovits and de Jong, 2004, Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 11 )
Research paper	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Bochdanovits and de Jong, 2004, Proc. r. Soc. Biol. Sci. 271(Suppl. 3): S75--S78 Antagonistic pleiotropy for life-history traits at the gene expression level. [FBrf0175102]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452] Kiger et al., 2003, J. Biol. 2(4): Additional data file 1: The gene identity and primer sequences for dsRNAs used in the RNAi screens. [FBrf0174231]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
DNA/RNA sequence record	Stapleton, 2001.10.8, GenBank/EMBL/DDBJ: AY059451 Drosophila melanogaster LD25304 full length cDNA. [FBrf0140511]