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Gene Dmel\eIF3-S10

General Information
Symbol	Dmel\eIF3-S10	Species	D. melanogaster
Name	eIF3-S10	Annotation symbol	CG9805
Feature type	protein_coding_gene	FlyBase ID	FBgn0037249
Gene Model Status	Current	Stock availability	7 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	82B1-82B1	Sequence location	3R:255,639..259,652 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene eIF3-S10 is referred to in FlyBase by the symbol Dmel\eIF3-S10 (CG9805, FBgn0037249). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: translation initiation factor activity. There is experimental evidence that it is involved in the biological process: mitotic spindle elongation; mitotic spindle organization. 9 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Proteasome component (PCI) domain; Winged helix-turn-helix transcription repressor DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult eye, larval central nervous system, larval hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult central nervous system, adult crop, larval/adult midgut, adult hindgut, larval fat body, adult testis, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1631404_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of eIF3-S10. Gene sequence location is 3R:255639..259652.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10	References Knowles-Barley, 2011.8.24, BrainTrap expression curation.
FB2012_01	References Lowery et al., 2010, Genetics 185(4): 1311--1325 Sequence features HFA12339 BKN22188
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 82B1-82B1   Limits computationally determined from genome sequence between P{PZ}l(3)0273302733 and P{EP}EP974
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\eIF3-S10 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) eIF3-S10-RA FBtr0078944  NM_141213   3808   1140
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein eIF3-S10-PA   FBpp0078584   133.9   1140   9.47     NP_649470   AAF52126
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Proteasome component (PCI) domain (IPR000717) Winged helix-turn-helix transcription repressor DNA-binding (IPR011991)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA141050   AA201140   AA201223   AA201661   AA201672   AA201833   AA201932   AA202007   AA202031   AA202117   AA202962   AA246988   AA263892   AA264411   AA390270   AA390780   AA390783   AA390983   AA391143   AA391301   AA391391   AA391700   AA438734   AA439211   AA439491   AA439499   AA440179   AA441211   AA441239   AA538573   AA538867   AA539034   AA539248   AA540649   AA694837   AA694989   AA694990   AA696030   AA697660   AA697992   AA698592   AA735535   AA735622   AA802973   AA803482   AA817107   AA817517   AA817597   AA820245   AA820436   AA820474   AA820591   AA940583   AA940873   AA941051   AA941056   AA941075   AA941088   AA941204   AA941444   AA942123   AA942317   AA942437   AA942568   AA949004   AA949221   AA949510   AA949711   AA949787   AA949969   AA950069   AA950160   AA951161   AA951460   AA951576   AA951661   AA951898   AA952193   AA978441   AA978520   AA978639   AA978788   AA978823   AA979193   AA979391   AA990646   AE014297 AAF52126   AI061895   AI061939   AI107063   AI107824   AI108322   AI108425   AI109210   AI134479   AI258274   AI259780   AI260119   AI261088   AI295490   AI297234   AI388285   AI389785   AI389806   AI390051   AI402447   AI402551   AI405342   AI455688   AI455734   AI455875   AI455889   AI455907   AI455919   AI456019   AI456165   AI456295   AI456337   AI456357   AI456472   AI456483   AI456833   AI456930   AI457047   AI457051   AI511792   AI512152   AI512586   AI512590   AI512686   AI512734   AI512772   AI512908   AI512968   AI513660   AI514409   AI514439   AI514489   AI514530   AI514544   AI514582   AI514683   AI515372   AI515479   AI515846   AI515938   AI516247   AI516289   AI516605   AI516749   AI518174   AI518393   AI518430   AI518917   AI519695   AI520066   AI520318   AI520329   AI520335   AI520356   AI531196   AI531213   AI531618   AI531653   AI532836   AI533221   AI533380   AI533635   AI533678   AI533890   AI533955   AI534280   AI534319   AI534506   AI534642   AI541579   AI542150   AI542326   AI542545   AI542556   AI542561   AI542565   AI542634   AI543023   AI543171   AI543177   AI543331   AI543812   AI543880   AI544024   AI544044   AI544164   AI546362   AI546419   AI546439   AI546622   AX094137   AY071601 AAL49223   BF497999   BF502186   BG634612   BG635901   BG638540   BG639073   BG640563   BG640901   BG640933   BI161799   BI162167   BI163298   BI163858   BI165666   BI166231   BI167476   BI167722   BI170144   BI171189   BI172491   BI172613   BI173265   BI212530   BI212773   BI213002   BI215043   BI228919   BI230365   BI230717   BI230779   BI231065   BI231687   BI232755   BI235537   BI236064   BI238919   BI239330   BI240032   BI351773   BI352287   BI352605   BI353418   BI353824   BI354004   BI354548   BI355104   BI356189   BI356561   BI358261   BI358594   BI361670   BI362153   BI362637   BI364140   BI364209   BI364280   BI365730   BI365793   BI365863   BI367657   BI370892   BI371127   BI481909   BI482503   BI483938   BI484438   BI484649   BI485526   BI485751   BI485797   BI486207   BI577716   BI577876   BI578952   BI579432   BI634744   BI635698   BI636102   BI637562   BI637634   BI637904   BI638176   BI638697   BI639282   BI639513   BI640488   BI641866   BT001505 AAN71260   BT023783   CK657644   CK659356   CK660373   CK662199   CK662326   CO155195   CO155712   CO155734   CO177870   CO188910   CO262548   CO270768   CO277329   CO288370   CO288595   CO295239   CO300112   CO303492   CO308878   CO312149   CO314869   CO330407   CO330458   CO338450   CZ480840   EC057513   EC065668   EC069339   EC072452   EC076053   EC076666   EC080001   EC080567   EC081843   EC085602   EC088590   EC197371   EC204297   EC204810   EC214287   EC217355   EC217666   EC227905   EC230602   EC235500   EC238271   EC242062   EC242699   EC243661   EC246207   EC247527   EC265711   EC266549   EC267137   EL872055   ES693779   EV578344   EV579261   EV589034
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VN25
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0037249    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0037249 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, during early pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0037249 expression level Developmental Stage   Expression Level embryo 00-02hr    17169 embryo 02-04hr    26558 embryo 04-06hr    26136 embryo 06-08hr    21570 embryo 08-10hr    21269 embryo 10-12hr    16090 embryo 12-14hr    11156 embryo 14-16hr    14980 embryo 16-18hr    11615 embryo 18-20hr    9943 embryo 20-22hr    17170 embryo 22-24hr    13435 larva L1    12775 larva L2    11384 larva L3 12hr old    9399 larva L3 puffstage 1-2    6871 larva L3 puffstage 3-6    8939 larva L3 puffstage 7-9    8738 white prepupae new    8858 white prepupae 12hr    8120 white prepupae 24hr    10165 pupae 2d postWPP    6516 pupae 3d postWPP    4682 pupae 4d postWPP    5849 adult male 01day    5682 adult male 05day    6420 adult male 30day    5634 adult female 01day    12820 adult female 05day    15012 adult female 30day    14218 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (17169) embryo 02-04hr  (26558) embryo 04-06hr  (26136) embryo 06-08hr  (21570) embryo 08-10hr  (21269) embryo 10-12hr  (16090) embryo 12-14hr  (11156) embryo 14-16hr  (14980) embryo 16-18hr  (11615) embryo 18-20hr  (9943) embryo 20-22hr  (17170) embryo 22-24hr  (13435) larva L1  (12775) larva L2  (11384) larva L3 12hr old  (9399) larva L3 puffstage 1-2  (6871) larva L3 puffstage 3-6  (8939) larva L3 puffstage 7-9  (8738) white prepupae new  (8858) white prepupae 12hr  (8120) white prepupae 24hr  (10165) pupae 2d postWPP  (6516) pupae 3d postWPP  (4682) pupae 4d postWPP  (5849) adult male 01day  (5682) adult male 05day  (6420) adult male 30day  (5634) adult female 01day  (12820) adult female 05day  (15012) adult female 30day  (14218) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (17169) embryo 02-04hr  (26558) embryo 04-06hr  (26136) embryo 06-08hr  (21570) embryo 08-10hr  (21269) embryo 10-12hr  (16090) embryo 12-14hr  (11156) embryo 14-16hr  (14980) embryo 16-18hr  (11615) embryo 18-20hr  (9943) embryo 20-22hr  (17170) embryo 22-24hr  (13435) larva L1  (12775) larva L2  (11384) larva L3 12hr old  (9399) larva L3 puffstage 1-2  (6871) larva L3 puffstage 3-6  (8939) larva L3 puffstage 7-9  (8738) white prepupae new  (8858) white prepupae 12hr  (8120) white prepupae 24hr  (10165) pupae 2d postWPP  (6516) pupae 3d postWPP  (4682) pupae 4d postWPP  (5849) adult male 01day  (5682) adult male 05day  (6420) adult male 30day  (5634) adult female 01day  (12820) adult female 05day  (15012) adult female 30day  (14218) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (17169) embryo 02-04hr  (26558) embryo 04-06hr  (26136) embryo 06-08hr  (21570) embryo 08-10hr  (21269) embryo 10-12hr  (16090) embryo 12-14hr  (11156) embryo 14-16hr  (14980) embryo 16-18hr  (11615) embryo 18-20hr    9943 embryo 20-22hr  (17170) embryo 22-24hr  (13435) larva L1  (12775) larva L2  (11384) larva L3 12hr old    9399 larva L3 puffstage 1-2    6871 larva L3 puffstage 3-6    8939 larva L3 puffstage 7-9    8738 white prepupae new    8858 white prepupae 12hr    8120 white prepupae 24hr  10165 pupae 2d postWPP    6516 pupae 3d postWPP    4682 pupae 4d postWPP    5849 adult male 01day    5682 adult male 05day    6420 adult male 30day    5634 adult female 01day  (12820) adult female 05day  (15012) adult female 30day  (14218) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    17169 embryo 02-04hr    26558 embryo 04-06hr    26136 embryo 06-08hr    21570 embryo 08-10hr    21269 embryo 10-12hr    16090 embryo 12-14hr    11156 embryo 14-16hr    14980 embryo 16-18hr    11615 embryo 18-20hr    9943 embryo 20-22hr    17170 embryo 22-24hr    13435 larva L1    12775 larva L2    11384 larva L3 12hr old    9399 larva L3 puffstage 1-2    6871 larva L3 puffstage 3-6    8939 larva L3 puffstage 7-9    8738 white prepupae new    8858 white prepupae 12hr    8120 white prepupae 24hr    10165 pupae 2d postWPP    6516 pupae 3d postWPP    4682 pupae 4d postWPP    5849 adult male 01day    5682 adult male 05day    6420 adult male 30day    5634 adult female 01day    12820 adult female 05day    15012 adult female 30day    14218 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0037249 expression level Developmental Stage   Expression Level embryo 00-02hr    17169 embryo 02-04hr    26558 embryo 04-06hr    26136 embryo 06-08hr    21570 embryo 08-10hr    21269 embryo 10-12hr    16090 embryo 12-14hr    11156 embryo 14-16hr    14980 embryo 16-18hr    11615 embryo 18-20hr    9943 embryo 20-22hr    17170 embryo 22-24hr    13435 larva L1    12775 larva L2    11384 larva L3 12hr old    9399 larva L3 puffstage 1-2    6871 larva L3 puffstage 3-6    8939 larva L3 puffstage 7-9    8738 white prepupae new    8858 white prepupae 12hr    8120 white prepupae 24hr    10165 pupae 2d postWPP    6516 pupae 3d postWPP    4682 pupae 4d postWPP    5849 adult male 01day    5682 adult male 05day    6420 adult male 30day    5634 adult female 01day    12820 adult female 05day    15012 adult female 30day    14218 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (17169) embryo 02-04hr  (26558) embryo 04-06hr  (26136) embryo 06-08hr  (21570) embryo 08-10hr  (21269) embryo 10-12hr  (16090) embryo 12-14hr  (11156) embryo 14-16hr  (14980) embryo 16-18hr  (11615) embryo 18-20hr  (9943) embryo 20-22hr  (17170) embryo 22-24hr  (13435) larva L1  (12775) larva L2  (11384) larva L3 12hr old  (9399) larva L3 puffstage 1-2  (6871) larva L3 puffstage 3-6  (8939) larva L3 puffstage 7-9  (8738) white prepupae new  (8858) white prepupae 12hr  (8120) white prepupae 24hr  (10165) pupae 2d postWPP  (6516) pupae 3d postWPP  (4682) pupae 4d postWPP  (5849) adult male 01day  (5682) adult male 05day  (6420) adult male 30day  (5634) adult female 01day  (12820) adult female 05day  (15012) adult female 30day  (14218) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (17169) embryo 02-04hr  (26558) embryo 04-06hr  (26136) embryo 06-08hr  (21570) embryo 08-10hr  (21269) embryo 10-12hr  (16090) embryo 12-14hr  (11156) embryo 14-16hr  (14980) embryo 16-18hr  (11615) embryo 18-20hr  (9943) embryo 20-22hr  (17170) embryo 22-24hr  (13435) larva L1  (12775) larva L2  (11384) larva L3 12hr old  (9399) larva L3 puffstage 1-2  (6871) larva L3 puffstage 3-6  (8939) larva L3 puffstage 7-9  (8738) white prepupae new  (8858) white prepupae 12hr  (8120) white prepupae 24hr  (10165) pupae 2d postWPP  (6516) pupae 3d postWPP  (4682) pupae 4d postWPP  (5849) adult male 01day  (5682) adult male 05day  (6420) adult male 30day  (5634) adult female 01day  (12820) adult female 05day  (15012) adult female 30day  (14218) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  17169 embryo 02-04hr  (26558) embryo 04-06hr  (26136) embryo 06-08hr  (21570) embryo 08-10hr  (21269) embryo 10-12hr  16090 embryo 12-14hr  11156 embryo 14-16hr  14980 embryo 16-18hr  11615 embryo 18-20hr    9943 embryo 20-22hr  17170 embryo 22-24hr  13435 larva L1  12775 larva L2  11384 larva L3 12hr old    9399 larva L3 puffstage 1-2    6871 larva L3 puffstage 3-6    8939 larva L3 puffstage 7-9    8738 white prepupae new    8858 white prepupae 12hr    8120 white prepupae 24hr  10165 pupae 2d postWPP    6516 pupae 3d postWPP    4682 pupae 4d postWPP    5849 adult male 01day    5682 adult male 05day    6420 adult male 30day    5634 adult female 01day  12820 adult female 05day  15012 adult female 30day  14218 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    17169 embryo 02-04hr    26558 embryo 04-06hr    26136 embryo 06-08hr    21570 embryo 08-10hr    21269 embryo 10-12hr    16090 embryo 12-14hr    11156 embryo 14-16hr    14980 embryo 16-18hr    11615 embryo 18-20hr    9943 embryo 20-22hr    17170 embryo 22-24hr    13435 larva L1    12775 larva L2    11384 larva L3 12hr old    9399 larva L3 puffstage 1-2    6871 larva L3 puffstage 3-6    8939 larva L3 puffstage 7-9    8738 white prepupae new    8858 white prepupae 12hr    8120 white prepupae 24hr    10165 pupae 2d postWPP    6516 pupae 3d postWPP    4682 pupae 4d postWPP    5849 adult male 01day    5682 adult male 05day    6420 adult male 30day    5634 adult female 01day    12820 adult female 05day    15012 adult female 30day    14218 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0037249    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0037249 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult eye, larval central nervous system, larval hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult central nervous system, adult crop, larval/adult midgut, adult hindgut, larval fat body, adult testis, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0037249 expression level Tissue   Expression Level Larval Central Nervous System    683.65 Larval Midgut    271.7 Larval Hindgut    717.5 Larval Malpighian Tubules    729.2 Larval Fat Body    444.1 Larval Salivary Gland    1492.6 Larval Trachea    875.55 Larval Carcass    654.65 Adult Head    360 Adult Eye    749.675 Adult Brain    397 Adult Thoracic-Abdominal Ganglion    476.2 Adult Crop    392.7 Adult Midgut    288.8 Adult Hindgut    401.6 Adult Malpighian Tubules    736.7 Adult Fat Body    617.3 Adult Salivary Gland    852.6 Adult Heart    553.375 Adult VirginFemale Spermatheca    1407 Adult InseminatedFemale Spermatheca    1331.1 Adult Ovary    620.5 Adult Testis    310.2 Adult Male Accessory Gland    1209.3 Adult Carcass    487.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (683.65) Larval Midgut    271.7 Larval Hindgut  (717.5) Larval Malpighian Tubules  (729.2) Larval Fat Body    444.1 Larval Salivary Gland  (1492.6) Larval Trachea  (875.55) Larval Carcass  (654.65) Adult Head    360 Adult Eye  (749.675) Adult Brain    397 Adult Thoracic-Abdominal Ganglion    476.2 Adult Crop    392.7 Adult Midgut    288.8 Adult Hindgut    401.6 Adult Malpighian Tubules  (736.7) Adult Fat Body  (617.3) Adult Salivary Gland  (852.6) Adult Heart  (553.375) Adult VirginFemale Spermatheca  (1407) Adult InseminatedFemale Spermatheca  (1331.1) Adult Ovary  (620.5) Adult Testis    310.2 Adult Male Accessory Gland  (1209.3) Adult Carcass    487.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    683.65 Larval Midgut    271.7 Larval Hindgut    717.5 Larval Malpighian Tubules    729.2 Larval Fat Body    444.1 Larval Salivary Gland  (1492.6) Larval Trachea    875.55 Larval Carcass    654.65 Adult Head    360 Adult Eye    749.675 Adult Brain    397 Adult Thoracic-Abdominal Ganglion    476.2 Adult Crop    392.7 Adult Midgut    288.8 Adult Hindgut    401.6 Adult Malpighian Tubules    736.7 Adult Fat Body    617.3 Adult Salivary Gland    852.6 Adult Heart    553.375 Adult VirginFemale Spermatheca  (1407) Adult InseminatedFemale Spermatheca  (1331.1) Adult Ovary    620.5 Adult Testis    310.2 Adult Male Accessory Gland  (1209.3) Adult Carcass    487.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    683.65 Larval Midgut    271.7 Larval Hindgut    717.5 Larval Malpighian Tubules    729.2 Larval Fat Body    444.1 Larval Salivary Gland    1492.6 Larval Trachea    875.55 Larval Carcass    654.65 Adult Head    360 Adult Eye    749.675 Adult Brain    397 Adult Thoracic-Abdominal Ganglion    476.2 Adult Crop    392.7 Adult Midgut    288.8 Adult Hindgut    401.6 Adult Malpighian Tubules    736.7 Adult Fat Body    617.3 Adult Salivary Gland    852.6 Adult Heart    553.375 Adult VirginFemale Spermatheca    1407 Adult InseminatedFemale Spermatheca    1331.1 Adult Ovary    620.5 Adult Testis    310.2 Adult Male Accessory Gland    1209.3 Adult Carcass    487.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0037249 expression level Tissue   Expression Level Larval Central Nervous System    683.65 Larval Midgut    271.7 Larval Hindgut    717.5 Larval Malpighian Tubules    729.2 Larval Fat Body    444.1 Larval Salivary Gland    1492.6 Larval Trachea    875.55 Larval Carcass    654.65 Adult Head    360 Adult Eye    749.675 Adult Brain    397 Adult Thoracic-Abdominal Ganglion    476.2 Adult Crop    392.7 Adult Midgut    288.8 Adult Hindgut    401.6 Adult Malpighian Tubules    736.7 Adult Fat Body    617.3 Adult Salivary Gland    852.6 Adult Heart    553.375 Adult VirginFemale Spermatheca    1407 Adult InseminatedFemale Spermatheca    1331.1 Adult Ovary    620.5 Adult Testis    310.2 Adult Male Accessory Gland    1209.3 Adult Carcass    487.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  683.65 Larval Midgut    271.7 Larval Hindgut  717.5 Larval Malpighian Tubules  729.2 Larval Fat Body    444.1 Larval Salivary Gland  (1492.6) Larval Trachea  (875.55) Larval Carcass  654.65 Adult Head    360 Adult Eye  749.675 Adult Brain    397 Adult Thoracic-Abdominal Ganglion    476.2 Adult Crop    392.7 Adult Midgut    288.8 Adult Hindgut    401.6 Adult Malpighian Tubules  736.7 Adult Fat Body  617.3 Adult Salivary Gland  (852.6) Adult Heart  553.375 Adult VirginFemale Spermatheca  (1407) Adult InseminatedFemale Spermatheca  (1331.1) Adult Ovary  620.5 Adult Testis    310.2 Adult Male Accessory Gland  (1209.3) Adult Carcass    487.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    683.65 Larval Midgut    271.7 Larval Hindgut    717.5 Larval Malpighian Tubules    729.2 Larval Fat Body    444.1 Larval Salivary Gland  1492.6 Larval Trachea    875.55 Larval Carcass    654.65 Adult Head    360 Adult Eye    749.675 Adult Brain    397 Adult Thoracic-Abdominal Ganglion    476.2 Adult Crop    392.7 Adult Midgut    288.8 Adult Hindgut    401.6 Adult Malpighian Tubules    736.7 Adult Fat Body    617.3 Adult Salivary Gland    852.6 Adult Heart    553.375 Adult VirginFemale Spermatheca  1407 Adult InseminatedFemale Spermatheca  1331.1 Adult Ovary    620.5 Adult Testis    310.2 Adult Male Accessory Gland  1209.3 Adult Carcass    487.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    683.65 Larval Midgut    271.7 Larval Hindgut    717.5 Larval Malpighian Tubules    729.2 Larval Fat Body    444.1 Larval Salivary Gland    1492.6 Larval Trachea    875.55 Larval Carcass    654.65 Adult Head    360 Adult Eye    749.675 Adult Brain    397 Adult Thoracic-Abdominal Ganglion    476.2 Adult Crop    392.7 Adult Midgut    288.8 Adult Hindgut    401.6 Adult Malpighian Tubules    736.7 Adult Fat Body    617.3 Adult Salivary Gland    852.6 Adult Heart    553.375 Adult VirginFemale Spermatheca    1407 Adult InseminatedFemale Spermatheca    1331.1 Adult Ovary    620.5 Adult Testis    310.2 Adult Male Accessory Gland    1209.3 Adult Carcass    487.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    360   NA  Eye    749.675   NA  Brain    397   683.65  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    476.2   NA  Crop    392.7   271.7  Midgut    288.8   717.5  Hindgut    401.6   729.2  Malpighian Tubules    736.7   444.1  Fat Body    617.3   1492.6  Salivary Gland    852.6   NA  Heart    553.375   875.55  Trachea    NA   NA  VirginFemale Spermatheca    1407   NA  InseminatedFemale Spermatheca    1331.1   NA  Ovary    620.5   NA  Testis    310.2   NA  Male Accessory Gland    1209.3   654.65  Carcass    487.4 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_08
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037249 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9805-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal eIF3-S10CB05493 lethal, with Scer\GAL4pnr-MD237 eIF3-S10GD12569 Phenotype manifest in Allele
Classical Alleles ( 5 )
For All Classical Alleles Show
Allele of eIF3-S10 Class Mutagen Stocks Known lesion eIF3-S10e03075 piggyBac transposase 1 -- eIF3-S10EY04238 P-element activity 1 -- eIF3-S10UM-8038-3 1 -- eIF3-S10CB05493 P-element activity 0 Yes eIF3-S10CPTI000076 piggyBac transposase 0 Yes
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of eIF3-S10 Class Mutagen Stocks Known lesion eIF3-S10GD12569 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes eIF3-S10HMS01342 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes eIF3-S10JF01699 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes eIF3-S10JF02719 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)BSC246 (Gresens and Cook, 2006.12.5)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD12569} NA P{TRiP.HMS01342} NA P{TRiP.JF01699} NA P{TRiP.JF02719} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{PTT-GB}eIF3-S10CB05493 NA P{RS3}eIF3-S10UM-8038-3 NA PBac{602.P.SVS-1}eIF3-S10CPTI000076 NA PBac{RB}eIF3-S10e03075 NA insertion of mobile activating element P{EPgy2}eIF3-S10EY04238 NA
Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
mitotic spindle elongation inferred from mutant phenotype (Goshima et al., 2007) mitotic spindle organization inferred from mutant phenotype (Goshima et al., 2007)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
translation initiation factor activity inferred from sequence or structural similarity (Lasko, 2000) inferred from sequence or structural similarity with EMBL:AL031739 (FlyBase, 1992-)
Biological Process
CV term Evidence References
translational initiation inferred from sequence or structural similarity (Lasko, 2000) inferred from sequence or structural similarity with EMBL:AL031739 (FlyBase, 1992-)
Cellular Component
CV term Evidence References
cytosol inferred from sequence or structural similarity (Lasko, 2000) eukaryotic translation initiation factor 3 complex inferred from sequence or structural similarity (Lasko, 2000) inferred from sequence or structural similarity with EMBL:AL031739 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions eIF3-S10 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 65782 DroID - A comprehensive database of gene and protein interactions. • FBgn0037249 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40563
Orthologs
Genome-wide drosophilid orthologs	Dana\GF16808 Dere\GG11565 Dgri\GH11742 Dmoj\GI22072 Dper\GL22350 Dpse\GA22048 Dsec\GM10701 Dsim\GD19678 Dvir\GJ10729 Dwil\GK13753 Dyak\GE25350
Curated drosophilid orthologs	Dpse\GA22048
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AGAP002340-PA Anopheles gambiae (mosquito) XP_397439.3 Apis mellifera (honey bee) XP_001946510.1 Acyrthosiphon pisum (pea aphid) At4g11420.1 Arabidopsis thaliana (wall cress) 15842 Batrachochytrium dendrobatidis (chytrid fungus) 75590 Branchiostoma floridae (lancelet) XP_001897252.1 Brugia malayi (roundworm nematode) BGIBMGA013025-PA Bombyx mori (silk worm) ENSBTAP00000003280 Bos taurus (bovine) CAL0001323 Candida albicans (a form of yeast) CN29165 Caenorhabditis brenneri (small nematode) CBP13719 Caenorhabditis briggsae (nematode) CE00543 Caenorhabditis elegans (worm) ENSCAFP00000017766 Canis familiaris (dog) CAGL0M01804g Candida glabrata (haploid yeast) ENSCINP00000009993 Ciona intestinalis (sea squirt) JA14010 Caenorhabditis japonica (nematode) CMH060C Cyanidioschyzon merolae (red alga) cn05334 Cryptococcus neoformans (yeast-like fungus) cgd5_390 Cryptosporidium parvum (protozoan parasite) CPIJ002784 Culex pipens (mosquito) ENSCPOP00000013690 Cavia porcellus (guinea pig) 187852 Chlamidomonas reinhardtii (green alga) RP32101 Caenorhabditis remanei (nematode) ENSCSAVP00000003589 Ciona savignyi (sedentary tunicate) 162196 Capitella spl (polychaete worm) DDB0233930 Dictyostelium discoideum (amoeba) DEHA2G10098g Debaryomyces Hansenii (yeast) 226467 Daphnia pulex (daphnia) ENSDARP00000058036 Danio rerio (zebra fish) ENSECAP00000019554 Equus caballus (horse) ENSGACP00000004184 Gymnopilus aculeatus (mushroom) ENSGALP00000015176 Gallus gallus (chicken) 63527 Hypsipyla robusta (cedar shoot borer) ENSP00000358140 Homo sapiens (human) ISCW020306-PA Ixodes scapularis (deer tick) KLLA0C14498g Kluyveromyces lactis (yeast) 142293 Lottia gigantea (owl limpet) 33388 Monocosta brevicollis (choanoflagellate) ENSMODP00000011639 Monodelphis domestica (gray opossum) ENSMUSP00000025955 Mus musculus (house mouse) 190699 Nematostella vectensis (starlet anemone) XP_001605611.1 Nasonia vitripennis (wasp) ENSOANP00000011713 Ornithorynchus anatinus (platypus) ENSORLP00000017833 Oryzias latipes (japanese killifish) LOC_Os01g03070.1 Oryza sativa (asian rice) 511 Ostreococcus tauri (green alga) PFL0625c Plasmodium falciparum (protozoal parasite) PHUM004374-PA Pediculus humanus (human body louse) PP01420 Pristionchus pacificus (nematode) 211874 Physcomitrella patens (moss) ENSPPYP00000003148 Pongo pygmaeus (orangutan) 74224 Phytophthora ramorum (sudden oak death pathogen) 139836 Phytophthora sojae (root rot pathogen) 744583 Populus trichocarpa (black cottonwood) ENSPTRP00000005269 Pan troglodytes (chimpanzee) PVX_123340 Plasmodium vivax (protozoal parasite) ENSRNOP00000013559 Rattus norvegicus (norway rat) 4751383 Sorghum bicolor (sorghum) YBR079C Saccharomyces cerevisiae (budding yeast) Smp_001170 Schistosoma mansoni (trematode parasite) SPBC17D11.05 Schizosaccharomyces pombe (fission yeast) XP_001196993.1 Strongylocentrotus purpuratus (purple sea urchin) 50583 Trichoplax adhaerens (metazoa) TA19545 Theileria annulata (apicomplexan parasite) XP_973312.1 Tribolium castaneum (red flour beetle) ENSTNIP00000006423 Tetraodon nigroviridis (green spotted pufferfish) TP01_0235 Theileria parva (parasitic protozoan) 262091 Thalassiosira pseudonana (marine diatom) ENSTRUP00000045687 Takifugu rubripes (pufferfish Takifugu) 138.m00130 Tetrahymena thermophila (ciliate protozoa) 93664.m00033 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000022578 Xenopus tropicalis (frog) YALI0F18942g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB14137 NV13962 LH22144 ISCW020306 FBgn0242428 FBgn0215761 FBgn0198006 FBgn0191169 FBgn0165647 JGI_V11_226467 FBgn0082032 FBgn0159942 FBgn0144801 FBgn0119222 FBgn0103862 FBgn0093829 CPIJ002784 BGIBMGA013025 ACYPI006266 GB12475 EIF3A_ANOGA AAEL007078 PHUM457140 GLEAN_12303
Stocks & Reagents
Stocks Listed in FlyBase ( 7 )
Bloomington	27565 y1 v1; P{TRiP.JF02719}attP2 31186 y1 v1; P{TRiP.JF01699}attP2 34353 y1 sc* v1; P{TRiP.HMS01342}attP2 15728 y1 w67c23; P{EPgy2}eIF3-S10EY04238/TM3, Sb1 Ser1
Harvard	- PBac{RB}eIF3-S10e03075
Kyoto	124298 w1118; P{RS3}eIF3-S10UM-8038-3
VDRC	v28140 w1118; P{GD12569}v28140/TM3
Genomic Clones ( 1 )
	BACR15E02 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 340 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD13709 LD35838 RE65203
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT12348 AT17838 AT30875 GH07137 GH08334 GH11953 GH21046 GH21513 GH21793 GM01640 GM01908 GM01909 GM04935 GM06677 GM13276 GM16070 GM18655 GM20014 GM23548 GM25276 GM25921 GM27239 GM29508 LD02237 LD03375 LD03635 LD03822 LD04081 LD04774 LD07187 LD08072 LD08821 LD09803 LD11646 LD15936 LD16105 LD18735 LD18923 LD20409 LD23759 LD24221 LD24402 LD25029 LD25045 LD25207 LD26170 LD26870 LD27733 LD28335 LD28552 LD28779 LD29279 LD29693 LD29803 LD30032 LD30090 LD30759 LD31483 LD32172 LD32309 LD33489 LD33938 LD34956 LD35029 LD35331 LD35395 LD35602 LD35617 LD35652 LD36028 LD36188 LD36279 LD36328 LD36504 LD36975 LD37102 LD37267 LD37614 LD37887 LD37935 LD38102 LD38668 LD39373 LD40008 LD40456 LD40466 LD40490 LD40906 LD41066 LD41086 LD41171 LD41649 LD42108 LD42529 LD42785 LD43079 LD43316 LD43889 LD44503 LD44507 LD45150 LD45544 LD45994 LD46041 LD47172 LD47329 LD47613 LD47922 LD48014 LP01424 LP03810 LP11493 LP17067 LP22442 LP24110 RE07875 RH38968 SD02134 SD02157 SD02722 SD02754 SD02859 SD04466 SD04971 SD05165 SD05531 SD05578 SD05866 SD06316 SD07056 SD07111 SD07386 SD07570 SD08270 SD08614 SD08896 SD08924 SD08936 SD08944 SD09061 SD09319 SD09589 SD09810 SD09833 SD10054 SD11655 SD12072 SD12119 SD13419 SD17125 SD17670 SD19601 SD19687 SD20052 SD20401 SD21053 SD21832 SD22105 SD23369 SD25516
Other clones	5026 31244 57252 59344 70936 79205 99072 107701 118851 121371 121631 156506 166264 190277 192554 524526 525525 571419 CK01.7C.A8 CK01.9B.F11 CK01.22C.E11 CK01.30A.H6 CK01.40A.C4 CK01.52B.F4 CK01.86C.D8 CK01.87B.B12 CK01.101C.C10 CK01.105D.C7 CK01.130C.D11 CK01119 Dmel_dig_017189_0631_2187 Dmel_dig_020070_0678_3281 Dmel_neb_014428_0361_0662 EK042354 EK054544 EK068348 EK068940 EK085732 EK100212 EK123842 EK177421 EK209012 EK227948 EK238124 EK241754 EK259554 EK295204 EK295324 EN05542 EN06616 EN06641 EN16830 GH05681 GH06355 GH07255 GH19124 GH21073 GH21668 GH25313 HL02946 HL03587 HL04991 IP04045 LD01111 LD03744 LD03889 LD04151 LD04808 LD06083 LD08890 LD08940 LD09225 LD10010 LD10275 LD13076 LD14075 LD14085 LD14786 LD18135 LD18503 LD21472 LD21633 LD22213 LD23176 LD23179 LD23572 LD24060 LD25002 LD25007 LD25583 LD26451 LD26660 LD28034 LD30586 LD31928 LD32187 LD32792 LD32947 LD32993 LD34447 LD35638 LD36515 LD37271 LD40443 LD40946 LD41012 LD41529 LD42045 LD44629 LD44719 LD44794 LD45011 LD45873 LD46065 LD47987 LP03269 LP05164 LP09147 LP18904 LP22234 RC0-DL0001-140700-114-A03 RE01196 RE01557 RE02658 RE03376 RE05604 RE06273 RE08172 RE10162 RE11510 RE12893 RE14743 RE15003 RE15146 RE15217 RE16051 RE17635 RE17952 RE18020 RE18301 RE21234 RE23304 RE26579 RE28878 RE31392 RE32056 RE35284 RE35794 RE36675 RE42276 RE42738 RE44977 RE45418 RE45987 RE46641 RE47239 RE49201 RE49273 RE49355 RE51101 RE51173 RE51255 RE53543 RE57665 RE57952 RE64531 RE66908 RE67541 RE67784 RE68872 RE69091 RE69142 RE69603 RE71438 RE71635 RE72906 RE73460
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0037249 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40563
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: eIF3-S10 CG9805 (Lasko, 2000)
Source for database merge of	Source for merge of: eIF3-S10 anon-WO0118547.261 (FlyBase, 1996-)
Additional comments	Source for merge of eIF3-S10 anon-WO0118547.261 was sequence comparison (date:051113). (FlyBase, 1996-)
Other Comments
	RNAi screen using dsRNA made from templates generated with primers directed against this gene results in aberrantly short, monopolar spindles when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA. (Goshima et al., 2007) RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells. (Boutros et al., 2004) Area matching Drosophila EST AA201223 (inverted). This EST forms a 2631bp contig with ESTs AA538867, AA439491, AA390780, AA390983, AA201661, AA391700 and AA202007. Seq. sim. to Human nucleopore gene. (Davies, 2001.3.15)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_141213 RefSeq (Proteins) • NP_649470 DDBJ / EMBL / GenBank • AA201223 AA439211 AAF52126 AAL49223 AAN71260 AI456019 AX094137 AY071601 BI482503 BT001505 CZ480840 Entrez Gene - A searchable database of RefSeq genes. • 40563 UniProtKB/TrEMBL • Q9VN25
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Proteasome component (PCI) domain (IPR000717) Winged helix-turn-helix transcription repressor DNA-binding (IPR011991)
Linkouts
	BioGRID - A database of protein and genetic interactions • 65782 DroID - A comprehensive database of gene and protein interactions. • FBgn0037249 DRSC - Results from RNAi screens. • FBgn0037249 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037249 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9805-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0037249 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40563 InParanoid A subset of ortholog calls from InParanoid. • AGAP002340-PA Anopheles gambiae (mosquito) XP_397439.3 Apis mellifera (honey bee) XP_001946510.1 Acyrthosiphon pisum (pea aphid) At4g11420.1 Arabidopsis thaliana (wall cress) 15842 Batrachochytrium dendrobatidis (chytrid fungus) 75590 Branchiostoma floridae (lancelet) XP_001897252.1 Brugia malayi (roundworm nematode) BGIBMGA013025-PA Bombyx mori (silk worm) ENSBTAP00000003280 Bos taurus (bovine) CAL0001323 Candida albicans (a form of yeast) CN29165 Caenorhabditis brenneri (small nematode) CBP13719 Caenorhabditis briggsae (nematode) CE00543 Caenorhabditis elegans (worm) ENSCAFP00000017766 Canis familiaris (dog) CAGL0M01804g Candida glabrata (haploid yeast) ENSCINP00000009993 Ciona intestinalis (sea squirt) JA14010 Caenorhabditis japonica (nematode) CMH060C Cyanidioschyzon merolae (red alga) cn05334 Cryptococcus neoformans (yeast-like fungus) cgd5_390 Cryptosporidium parvum (protozoan parasite) CPIJ002784 Culex pipens (mosquito) ENSCPOP00000013690 Cavia porcellus (guinea pig) 187852 Chlamidomonas reinhardtii (green alga) RP32101 Caenorhabditis remanei (nematode) ENSCSAVP00000003589 Ciona savignyi (sedentary tunicate) 162196 Capitella spl (polychaete worm) DDB0233930 Dictyostelium discoideum (amoeba) DEHA2G10098g Debaryomyces Hansenii (yeast) 226467 Daphnia pulex (daphnia) ENSDARP00000058036 Danio rerio (zebra fish) ENSECAP00000019554 Equus caballus (horse) ENSGACP00000004184 Gymnopilus aculeatus (mushroom) ENSGALP00000015176 Gallus gallus (chicken) 63527 Hypsipyla robusta (cedar shoot borer) ENSP00000358140 Homo sapiens (human) ISCW020306-PA Ixodes scapularis (deer tick) KLLA0C14498g Kluyveromyces lactis (yeast) 142293 Lottia gigantea (owl limpet) 33388 Monocosta brevicollis (choanoflagellate) ENSMODP00000011639 Monodelphis domestica (gray opossum) ENSMUSP00000025955 Mus musculus (house mouse) 190699 Nematostella vectensis (starlet anemone) XP_001605611.1 Nasonia vitripennis (wasp) ENSOANP00000011713 Ornithorynchus anatinus (platypus) ENSORLP00000017833 Oryzias latipes (japanese killifish) LOC_Os01g03070.1 Oryza sativa (asian rice) 511 Ostreococcus tauri (green alga) PFL0625c Plasmodium falciparum (protozoal parasite) PHUM004374-PA Pediculus humanus (human body louse) PP01420 Pristionchus pacificus (nematode) 211874 Physcomitrella patens (moss) ENSPPYP00000003148 Pongo pygmaeus (orangutan) 74224 Phytophthora ramorum (sudden oak death pathogen) 139836 Phytophthora sojae (root rot pathogen) 744583 Populus trichocarpa (black cottonwood) ENSPTRP00000005269 Pan troglodytes (chimpanzee) PVX_123340 Plasmodium vivax (protozoal parasite) ENSRNOP00000013559 Rattus norvegicus (norway rat) 4751383 Sorghum bicolor (sorghum) YBR079C Saccharomyces cerevisiae (budding yeast) Smp_001170 Schistosoma mansoni (trematode parasite) SPBC17D11.05 Schizosaccharomyces pombe (fission yeast) XP_001196993.1 Strongylocentrotus purpuratus (purple sea urchin) 50583 Trichoplax adhaerens (metazoa) TA19545 Theileria annulata (apicomplexan parasite) XP_973312.1 Tribolium castaneum (red flour beetle) ENSTNIP00000006423 Tetraodon nigroviridis (green spotted pufferfish) TP01_0235 Theileria parva (parasitic protozoan) 262091 Thalassiosira pseudonana (marine diatom) ENSTRUP00000045687 Takifugu rubripes (pufferfish Takifugu) 138.m00130 Tetrahymena thermophila (ciliate protozoa) 93664.m00033 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000022578 Xenopus tropicalis (frog) YALI0F18942g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40563 modMine - Data generated by the modENCODE project. • FBgn0037249 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB14137 NV13962 LH22144 ISCW020306 FBgn0242428 FBgn0215761 FBgn0198006 FBgn0191169 FBgn0165647 JGI_V11_226467 FBgn0082032 FBgn0159942 FBgn0144801 FBgn0119222 FBgn0103862 FBgn0093829 CPIJ002784 BGIBMGA013025 ACYPI006266 GB12475 EIF3A_ANOGA AAEL007078 PHUM457140 GLEAN_12303
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	anon-WO0118547.261   CG9805 (Khokhar et al., 2008, Boutros et al., 2004, Lasko, 2000, Goshima et al., 2007, Perkins et al., 2009, Ni et al., 2008, Ni et al., 2010.12.1) eIF3-S10 (Khokhar et al., 2008, Gresens and Cook, 2006.12.5, Blanco et al., 2010, Stuart et al., 2007, Buszczak et al., 2007, Goshima et al., 2007, Andersen and Leevers, 2007, Somma et al., 2008, Lowery et al., 2010) MMAP140 (Sisson et al., 2000)
Name Synonym	eIF3-S10 (Somma et al., 2008)
Secondary FlyBase IDs
	FBan0009805 FBgn0062137
References ( 34 )
Generate a list of	All references relating to this gene ( 34 )
List References by type	Research paper  ( 12 ) Supplementary material  ( 5 ) Personal communication to FlyBase  ( 7 ) FlyBase analysis  ( 3 ) Patent  ( 1 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 3 ) Automatic genome annotation  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 2 )
	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Lowery et al., 2010, Genetics 185(4): 1311--1325 Parallel Genetic and Proteomic Screens Identify Msps as a CLASP-Abl Pathway Interactor in Drosophila. [FBrf0211499] Show all research papers ...