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Gene Dmel\CG12162

General Information
Symbol	Dmel\CG12162	Species	D. melanogaster
Name		Annotation symbol	CG12162
Feature type	protein_coding_gene	FlyBase ID	FBgn0037329
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	83A4-83A4	Sequence location	3R:1,293,515..1,295,288 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG12162 (FBgn0037329). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: ApaG domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1639011_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG12162. Gene sequence location is 3R:1293515..1295288.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10	Controlled Vocabulary Terms day 42 of adulthood day 41 of adulthood day 30 of adulthood day 49 of adulthood day 17 of adulthood day 45 of adulthood day 8 of adulthood day 26 of adulthood day 21 of adulthood day 13 of adulthood day 25 of adulthood day 20 of adulthood day 22 of adulthood day 39 of adulthood day 7 of adulthood day 36 of adulthood day 11 of adulthood day 37 of adulthood day 27 of adulthood day 18 of adulthood day 19 of adulthood day 28 of adulthood day 9 of adulthood day 29 of adulthood adult heart day 40 of adulthood day 16 of adulthood day 24 of adulthood day 15 of adulthood day 33 of adulthood day 43 of adulthood day 47 of adulthood day 38 of adulthood day 32 of adulthood day 48 of adulthood day 23 of adulthood day 35 of adulthood day 12 of adulthood day 10 of adulthood day 31 of adulthood day 34 of adulthood day 44 of adulthood day 14 of adulthood day 46 of adulthood
FB2012_01	Sequence features BKN28940 HFA12194
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 83A4-83A4   Limits computationally determined from genome sequence between P{EP}EP974 and P{PZ}Snr101319&P{PZ}Itp-r83A05616
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG12162 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG12162-RA FBtr0078680  NM_141283   1580   410 CG12162-RB FBtr0078681  NM_169054   1612   431
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG12162-PA   FBpp0078329   46.3   410   7.14     NP_649540   AAF52026 CG12162-PB   FBpp0078330   48.0   431   6.40     NP_730934   AAN13239
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • ApaG domain (IPR007474)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201712   AE014297 AAF52026   AE014297 AAN13239   AI134376   AI258496   AI534870   AW940427   AY069102 AAL39247   BE977605   BE977745   BE977747   BE978267   BE978414   BE978688   BF486576   BF486969   BF486975   BF486993   BF487090   BF487501   BF487622   BF488783   BF489250   BF489785   BF490238   BF490775   BF491432   BF491892   BF491898   BF492146   BF492734   BF492735   BF493162   BF493292   BF493940   BF494357   BF494962   BF495711   BF496468   BF496686   BF496820   BF497091   BF497202   BF497369   BF497692   BF498220   BF499152   BF499386   BF501012   BF501366   BF501420   BF502718   BF503089   BF503108   BF504430   BF504771   BF504847   BF505389   BF505685   BF505986   BF506215   BF506327   BF506429   BG633708   BG633741   BG633782   BG633839   BG634006   BG634264   BG635255   BG636523   BI173000   BI240159   BI352322   BI356469   BI357830   BI632679   BP552043   BP552044   CK605196   CK605197   CL526049   CO177185   CO189753   CO278034   CO297433   CO343199   CO344701   EC058145   EC062939   EC063837   EC071760   EC075880   EC257499   EC260576   EL873025   EL873290   GH740993   GH741075   GH741366   GH743897   GH744514   GH765241   GH768928   GH768931   GH779675
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8IPQ6 Q9VNC0
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0037329    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0037329 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0037329 expression level Developmental Stage   Expression Level embryo 00-02hr    3618 embryo 02-04hr    2813 embryo 04-06hr    2420 embryo 06-08hr    2964 embryo 08-10hr    2641 embryo 10-12hr    3115 embryo 12-14hr    1987 embryo 14-16hr    2445 embryo 16-18hr    1873 embryo 18-20hr    2122 embryo 20-22hr    1809 embryo 22-24hr    1530 larva L1    2207 larva L2    2440 larva L3 12hr old    2112 larva L3 puffstage 1-2    1202 larva L3 puffstage 3-6    1772 larva L3 puffstage 7-9    1751 white prepupae new    1682 white prepupae 12hr    2625 white prepupae 24hr    3971 pupae 2d postWPP    5113 pupae 3d postWPP    6319 pupae 4d postWPP    7668 adult male 01day    11588 adult male 05day    13676 adult male 30day    13377 adult female 01day    3277 adult female 05day    2222 adult female 30day    2248 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3618) embryo 02-04hr  (2813) embryo 04-06hr  (2420) embryo 06-08hr  (2964) embryo 08-10hr  (2641) embryo 10-12hr  (3115) embryo 12-14hr  (1987) embryo 14-16hr  (2445) embryo 16-18hr  (1873) embryo 18-20hr  (2122) embryo 20-22hr  (1809) embryo 22-24hr  (1530) larva L1  (2207) larva L2  (2440) larva L3 12hr old  (2112) larva L3 puffstage 1-2  (1202) larva L3 puffstage 3-6  (1772) larva L3 puffstage 7-9  (1751) white prepupae new  (1682) white prepupae 12hr  (2625) white prepupae 24hr  (3971) pupae 2d postWPP  (5113) pupae 3d postWPP  (6319) pupae 4d postWPP  (7668) adult male 01day  (11588) adult male 05day  (13676) adult male 30day  (13377) adult female 01day  (3277) adult female 05day  (2222) adult female 30day  (2248) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3618) embryo 02-04hr  (2813) embryo 04-06hr  (2420) embryo 06-08hr  (2964) embryo 08-10hr  (2641) embryo 10-12hr  (3115) embryo 12-14hr  (1987) embryo 14-16hr  (2445) embryo 16-18hr  (1873) embryo 18-20hr  (2122) embryo 20-22hr  (1809) embryo 22-24hr  (1530) larva L1  (2207) larva L2  (2440) larva L3 12hr old  (2112) larva L3 puffstage 1-2    1202 larva L3 puffstage 3-6  (1772) larva L3 puffstage 7-9  (1751) white prepupae new  (1682) white prepupae 12hr  (2625) white prepupae 24hr  (3971) pupae 2d postWPP  (5113) pupae 3d postWPP  (6319) pupae 4d postWPP  (7668) adult male 01day  (11588) adult male 05day  (13676) adult male 30day  (13377) adult female 01day  (3277) adult female 05day  (2222) adult female 30day  (2248) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3618 embryo 02-04hr    2813 embryo 04-06hr    2420 embryo 06-08hr    2964 embryo 08-10hr    2641 embryo 10-12hr    3115 embryo 12-14hr    1987 embryo 14-16hr    2445 embryo 16-18hr    1873 embryo 18-20hr    2122 embryo 20-22hr    1809 embryo 22-24hr    1530 larva L1    2207 larva L2    2440 larva L3 12hr old    2112 larva L3 puffstage 1-2    1202 larva L3 puffstage 3-6    1772 larva L3 puffstage 7-9    1751 white prepupae new    1682 white prepupae 12hr    2625 white prepupae 24hr    3971 pupae 2d postWPP    5113 pupae 3d postWPP    6319 pupae 4d postWPP    7668 adult male 01day  (11588) adult male 05day  (13676) adult male 30day  (13377) adult female 01day    3277 adult female 05day    2222 adult female 30day    2248 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3618 embryo 02-04hr    2813 embryo 04-06hr    2420 embryo 06-08hr    2964 embryo 08-10hr    2641 embryo 10-12hr    3115 embryo 12-14hr    1987 embryo 14-16hr    2445 embryo 16-18hr    1873 embryo 18-20hr    2122 embryo 20-22hr    1809 embryo 22-24hr    1530 larva L1    2207 larva L2    2440 larva L3 12hr old    2112 larva L3 puffstage 1-2    1202 larva L3 puffstage 3-6    1772 larva L3 puffstage 7-9    1751 white prepupae new    1682 white prepupae 12hr    2625 white prepupae 24hr    3971 pupae 2d postWPP    5113 pupae 3d postWPP    6319 pupae 4d postWPP    7668 adult male 01day    11588 adult male 05day    13676 adult male 30day    13377 adult female 01day    3277 adult female 05day    2222 adult female 30day    2248 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0037329 expression level Developmental Stage   Expression Level embryo 00-02hr    3618 embryo 02-04hr    2813 embryo 04-06hr    2420 embryo 06-08hr    2964 embryo 08-10hr    2641 embryo 10-12hr    3115 embryo 12-14hr    1987 embryo 14-16hr    2445 embryo 16-18hr    1873 embryo 18-20hr    2122 embryo 20-22hr    1809 embryo 22-24hr    1530 larva L1    2207 larva L2    2440 larva L3 12hr old    2112 larva L3 puffstage 1-2    1202 larva L3 puffstage 3-6    1772 larva L3 puffstage 7-9    1751 white prepupae new    1682 white prepupae 12hr    2625 white prepupae 24hr    3971 pupae 2d postWPP    5113 pupae 3d postWPP    6319 pupae 4d postWPP    7668 adult male 01day    11588 adult male 05day    13676 adult male 30day    13377 adult female 01day    3277 adult female 05day    2222 adult female 30day    2248 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3618) embryo 02-04hr  (2813) embryo 04-06hr  (2420) embryo 06-08hr  (2964) embryo 08-10hr  (2641) embryo 10-12hr  (3115) embryo 12-14hr  (1987) embryo 14-16hr  (2445) embryo 16-18hr  (1873) embryo 18-20hr  (2122) embryo 20-22hr  (1809) embryo 22-24hr  (1530) larva L1  (2207) larva L2  (2440) larva L3 12hr old  (2112) larva L3 puffstage 1-2  (1202) larva L3 puffstage 3-6  (1772) larva L3 puffstage 7-9  (1751) white prepupae new  (1682) white prepupae 12hr  (2625) white prepupae 24hr  (3971) pupae 2d postWPP  (5113) pupae 3d postWPP  (6319) pupae 4d postWPP  (7668) adult male 01day  (11588) adult male 05day  (13676) adult male 30day  (13377) adult female 01day  (3277) adult female 05day  (2222) adult female 30day  (2248) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3618) embryo 02-04hr  (2813) embryo 04-06hr  2420 embryo 06-08hr  (2964) embryo 08-10hr  (2641) embryo 10-12hr  (3115) embryo 12-14hr  1987 embryo 14-16hr  2445 embryo 16-18hr  1873 embryo 18-20hr  2122 embryo 20-22hr  1809 embryo 22-24hr  1530 larva L1  2207 larva L2  2440 larva L3 12hr old  2112 larva L3 puffstage 1-2    1202 larva L3 puffstage 3-6  1772 larva L3 puffstage 7-9  1751 white prepupae new  1682 white prepupae 12hr  (2625) white prepupae 24hr  (3971) pupae 2d postWPP  (5113) pupae 3d postWPP  (6319) pupae 4d postWPP  (7668) adult male 01day  (11588) adult male 05day  (13676) adult male 30day  (13377) adult female 01day  (3277) adult female 05day  2222 adult female 30day  2248 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3618 embryo 02-04hr    2813 embryo 04-06hr    2420 embryo 06-08hr    2964 embryo 08-10hr    2641 embryo 10-12hr    3115 embryo 12-14hr    1987 embryo 14-16hr    2445 embryo 16-18hr    1873 embryo 18-20hr    2122 embryo 20-22hr    1809 embryo 22-24hr    1530 larva L1    2207 larva L2    2440 larva L3 12hr old    2112 larva L3 puffstage 1-2    1202 larva L3 puffstage 3-6    1772 larva L3 puffstage 7-9    1751 white prepupae new    1682 white prepupae 12hr    2625 white prepupae 24hr    3971 pupae 2d postWPP    5113 pupae 3d postWPP    6319 pupae 4d postWPP    7668 adult male 01day  11588 adult male 05day  13676 adult male 30day  13377 adult female 01day    3277 adult female 05day    2222 adult female 30day    2248 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3618 embryo 02-04hr    2813 embryo 04-06hr    2420 embryo 06-08hr    2964 embryo 08-10hr    2641 embryo 10-12hr    3115 embryo 12-14hr    1987 embryo 14-16hr    2445 embryo 16-18hr    1873 embryo 18-20hr    2122 embryo 20-22hr    1809 embryo 22-24hr    1530 larva L1    2207 larva L2    2440 larva L3 12hr old    2112 larva L3 puffstage 1-2    1202 larva L3 puffstage 3-6    1772 larva L3 puffstage 7-9    1751 white prepupae new    1682 white prepupae 12hr    2625 white prepupae 24hr    3971 pupae 2d postWPP    5113 pupae 3d postWPP    6319 pupae 4d postWPP    7668 adult male 01day    11588 adult male 05day    13676 adult male 30day    13377 adult female 01day    3277 adult female 05day    2222 adult female 30day    2248 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0037329    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0037329 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, adult female reproductive system, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0037329 expression level Tissue   Expression Level Larval Central Nervous System    166.075 Larval Midgut    143.9 Larval Hindgut    143.7 Larval Malpighian Tubules    110.3 Larval Fat Body    237.3 Larval Salivary Gland    122.5 Larval Trachea    85.725 Larval Carcass    148.575 Adult Head    209.4 Adult Eye    163.8 Adult Brain    258.5 Adult Thoracic-Abdominal Ganglion    359.7 Adult Crop    203 Adult Midgut    150.3 Adult Hindgut    206.7 Adult Malpighian Tubules    168.1 Adult Fat Body    216 Adult Salivary Gland    162.9 Adult Heart    166.65 Adult VirginFemale Spermatheca    218.5 Adult InseminatedFemale Spermatheca    187.8 Adult Ovary    209.5 Adult Testis    1409.9 Adult Male Accessory Gland    138.7 Adult Carcass    470.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    166.075 Larval Midgut    143.9 Larval Hindgut    143.7 Larval Malpighian Tubules    110.3 Larval Fat Body    237.3 Larval Salivary Gland    122.5 Larval Trachea    85.725 Larval Carcass    148.575 Adult Head    209.4 Adult Eye    163.8 Adult Brain    258.5 Adult Thoracic-Abdominal Ganglion    359.7 Adult Crop    203 Adult Midgut    150.3 Adult Hindgut    206.7 Adult Malpighian Tubules    168.1 Adult Fat Body    216 Adult Salivary Gland    162.9 Adult Heart    166.65 Adult VirginFemale Spermatheca    218.5 Adult InseminatedFemale Spermatheca    187.8 Adult Ovary    209.5 Adult Testis  (1409.9) Adult Male Accessory Gland    138.7 Adult Carcass    470.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    166.075 Larval Midgut    143.9 Larval Hindgut    143.7 Larval Malpighian Tubules    110.3 Larval Fat Body    237.3 Larval Salivary Gland    122.5 Larval Trachea    85.725 Larval Carcass    148.575 Adult Head    209.4 Adult Eye    163.8 Adult Brain    258.5 Adult Thoracic-Abdominal Ganglion    359.7 Adult Crop    203 Adult Midgut    150.3 Adult Hindgut    206.7 Adult Malpighian Tubules    168.1 Adult Fat Body    216 Adult Salivary Gland    162.9 Adult Heart    166.65 Adult VirginFemale Spermatheca    218.5 Adult InseminatedFemale Spermatheca    187.8 Adult Ovary    209.5 Adult Testis  (1409.9) Adult Male Accessory Gland    138.7 Adult Carcass    470.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    166.075 Larval Midgut    143.9 Larval Hindgut    143.7 Larval Malpighian Tubules    110.3 Larval Fat Body    237.3 Larval Salivary Gland    122.5 Larval Trachea    85.725 Larval Carcass    148.575 Adult Head    209.4 Adult Eye    163.8 Adult Brain    258.5 Adult Thoracic-Abdominal Ganglion    359.7 Adult Crop    203 Adult Midgut    150.3 Adult Hindgut    206.7 Adult Malpighian Tubules    168.1 Adult Fat Body    216 Adult Salivary Gland    162.9 Adult Heart    166.65 Adult VirginFemale Spermatheca    218.5 Adult InseminatedFemale Spermatheca    187.8 Adult Ovary    209.5 Adult Testis    1409.9 Adult Male Accessory Gland    138.7 Adult Carcass    470.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0037329 expression level Tissue   Expression Level Larval Central Nervous System    166.075 Larval Midgut    143.9 Larval Hindgut    143.7 Larval Malpighian Tubules    110.3 Larval Fat Body    237.3 Larval Salivary Gland    122.5 Larval Trachea    85.725 Larval Carcass    148.575 Adult Head    209.4 Adult Eye    163.8 Adult Brain    258.5 Adult Thoracic-Abdominal Ganglion    359.7 Adult Crop    203 Adult Midgut    150.3 Adult Hindgut    206.7 Adult Malpighian Tubules    168.1 Adult Fat Body    216 Adult Salivary Gland    162.9 Adult Heart    166.65 Adult VirginFemale Spermatheca    218.5 Adult InseminatedFemale Spermatheca    187.8 Adult Ovary    209.5 Adult Testis    1409.9 Adult Male Accessory Gland    138.7 Adult Carcass    470.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    166.075 Larval Midgut    143.9 Larval Hindgut    143.7 Larval Malpighian Tubules    110.3 Larval Fat Body    237.3 Larval Salivary Gland    122.5 Larval Trachea    85.725 Larval Carcass    148.575 Adult Head    209.4 Adult Eye    163.8 Adult Brain    258.5 Adult Thoracic-Abdominal Ganglion    359.7 Adult Crop    203 Adult Midgut    150.3 Adult Hindgut    206.7 Adult Malpighian Tubules    168.1 Adult Fat Body    216 Adult Salivary Gland    162.9 Adult Heart    166.65 Adult VirginFemale Spermatheca    218.5 Adult InseminatedFemale Spermatheca    187.8 Adult Ovary    209.5 Adult Testis  (1409.9) Adult Male Accessory Gland    138.7 Adult Carcass    470.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    166.075 Larval Midgut    143.9 Larval Hindgut    143.7 Larval Malpighian Tubules    110.3 Larval Fat Body    237.3 Larval Salivary Gland    122.5 Larval Trachea    85.725 Larval Carcass    148.575 Adult Head    209.4 Adult Eye    163.8 Adult Brain    258.5 Adult Thoracic-Abdominal Ganglion    359.7 Adult Crop    203 Adult Midgut    150.3 Adult Hindgut    206.7 Adult Malpighian Tubules    168.1 Adult Fat Body    216 Adult Salivary Gland    162.9 Adult Heart    166.65 Adult VirginFemale Spermatheca    218.5 Adult InseminatedFemale Spermatheca    187.8 Adult Ovary    209.5 Adult Testis  1409.9 Adult Male Accessory Gland    138.7 Adult Carcass    470.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    166.075 Larval Midgut    143.9 Larval Hindgut    143.7 Larval Malpighian Tubules    110.3 Larval Fat Body    237.3 Larval Salivary Gland    122.5 Larval Trachea    85.725 Larval Carcass    148.575 Adult Head    209.4 Adult Eye    163.8 Adult Brain    258.5 Adult Thoracic-Abdominal Ganglion    359.7 Adult Crop    203 Adult Midgut    150.3 Adult Hindgut    206.7 Adult Malpighian Tubules    168.1 Adult Fat Body    216 Adult Salivary Gland    162.9 Adult Heart    166.65 Adult VirginFemale Spermatheca    218.5 Adult InseminatedFemale Spermatheca    187.8 Adult Ovary    209.5 Adult Testis    1409.9 Adult Male Accessory Gland    138.7 Adult Carcass    470.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    209.4   NA  Eye    163.8   NA  Brain    258.5   166.075  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    359.7   NA  Crop    203   143.9  Midgut    150.3   143.7  Hindgut    206.7   110.3  Malpighian Tubules    168.1   237.3  Fat Body    216   122.5  Salivary Gland    162.9   NA  Heart    166.65   85.725  Trachea    NA   NA  VirginFemale Spermatheca    218.5   NA  InseminatedFemale Spermatheca    187.8   NA  Ovary    209.5   NA  Testis    1409.9   NA  Male Accessory Gland    138.7   148.575  Carcass    470.7 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_00
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037329 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12162-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG12162EY08866 viable, with Scer\GAL4pnr-MD237 CG12162GD7510 Sterility Allele fertile CG12162EY08866 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG12162 Class Mutagen Stocks Known lesion CG12162EY08866 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG12162 Class Mutagen Stocks Known lesion CG12162GD7510 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG12162KK108940 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7510} NA P{KK108940} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}CG12162EY08866 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG12162 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 65864 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0037329 DroID - A comprehensive database of gene and protein interactions. • FBgn0037329 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40655
Orthologs
Genome-wide drosophilid orthologs	Dana\GF17253 Dere\GG12826 Dgri\GH18595 Dmoj\GI23078 Dper\GL21664 Dpse\GA11446 Dsec\GM10809 Dsim\GD19787 Dvir\GJ22698 Dwil\GK11224 Dyak\GE25469
Curated drosophilid orthologs	Dpse\GA11446
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL011113-PA Aedes aegypti (mosquito) AGAP001153-PA Anopheles gambiae (mosquito) XP_001948226.1 Acyrthosiphon pisum (pea aphid) 244448 Branchiostoma floridae (lancelet) XP_001896723.1 Brugia malayi (roundworm nematode) BGIBMGA013121-PA Bombyx mori (silk worm) ENSBTAP00000010675 Bos taurus (bovine) CN27906 Caenorhabditis brenneri (small nematode) CBP26844 Caenorhabditis briggsae (nematode) CE37465 Caenorhabditis elegans (worm) ENSCAFP00000027538 Canis familiaris (dog) ENSCINP00000016033 Ciona intestinalis (sea squirt) JA01907 Caenorhabditis japonica (nematode) CPIJ013390 Culex pipens (mosquito) ENSCPOP00000002859 Cavia porcellus (guinea pig) RP36232 Caenorhabditis remanei (nematode) ENSCSAVP00000011862 Ciona savignyi (sedentary tunicate) 164871 Capitella spl (polychaete worm) 203725 Daphnia pulex (daphnia) ENSDARP00000072478 Danio rerio (zebra fish) ENSECAP00000011943 Equus caballus (horse) ENSGACP00000007163 Gymnopilus aculeatus (mushroom) ENSGALP00000005078 Gallus gallus (chicken) 114796 Hypsipyla robusta (cedar shoot borer) ENSP00000003607 Homo sapiens (human) ISCW009788-PA Ixodes scapularis (deer tick) 121872 Lottia gigantea (owl limpet) 26103 Monocosta brevicollis (choanoflagellate) ENSMODP00000024011 Monodelphis domestica (gray opossum) ENSMMUP00000025165 Macaca mulatta (rhesus monkey) ENSMUSP00000001127 Mus musculus (house mouse) 175505 Nematostella vectensis (starlet anemone) XP_001599719.1 Nasonia vitripennis (wasp) ENSOANP00000024609 Ornithorynchus anatinus (platypus) ENSORLP00000012315 Oryzias latipes (japanese killifish) PHUM009901-PA Pediculus humanus (human body louse) PP07816 Pristionchus pacificus (nematode) 224718 Physcomitrella patens (moss) ENSPPYP00000009096 Pongo pygmaeus (orangutan) ENSPTRP00000015214 Pan troglodytes (chimpanzee) ENSRNOP00000013100 Rattus norvegicus (norway rat) 5060187 Sorghum bicolor (sorghum) Smp_024500.1 Schistosoma mansoni (trematode parasite) XP_001194865.1 Strongylocentrotus purpuratus (purple sea urchin) 58326 Trichoplax adhaerens (metazoa) XP_966471.1 Tribolium castaneum (red flour beetle) Tc00.1047053507515.80 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053508211.70 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000017301 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000027796 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000051302 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB15118 NV15451 LH24191 ISCW009788 FBgn0242537 FBgn0213235 FBgn0209802 FBgn0191276 FBgn0165755 JGI_V11_203725 FBgn0071497 FBgn0159257 FBgn0145805 FBgn0126062 FBgn0105103 FBgn0094271 CPIJ013390 BGIBMGA013121 ACYPI006884 GB10300 AGAP001153 AAEL011113 PHUM455680 GLEAN_14911
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	17500 y1 w67c23; P{EPgy2}CG12162EY08866
VDRC	v20155 w1118; P{GD7510}v20155 v20156 w1118; P{GD7510}v20156
Genomic Clones ( 2 )
	BACR24O24 BACR34M23 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 99 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH11824
Other clones	DPiM_GH11824
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT01460 AT01617 AT02330 AT02821 AT03753 AT05786 AT06680 AT06882 AT07606 AT07959 AT08330 AT08632 AT08768 AT08889 AT09351 AT10390 AT10578 AT10811 AT11161 AT11323 AT11529 AT11930 AT12594 AT13657 AT13936 AT16196 AT16661 AT16737 AT18527 AT18995 AT19018 AT20912 AT21581 AT21593 AT21636 AT21773 AT22322 AT22595 AT24426 AT25194 AT25938 AT26556 AT27357 AT28170 AT28657 AT28664 AT29031 AT29415 AT29461 AT29705 AT29779 AT30028 AT30421 AT31775 GM18805 LD04917 LP01709 RE15731 RE36834 RE42634 RE44417 SD01134 SD14256 SD26516
Other clones	6121 60712 74522 83564 214321.53 214467.56 AT01162 bs66f12 bs68e06 bs68e08 bs76c02 bs79e05 bs81f11 CK01.67A.E3 EK045102 EK052718 EK128555 EK216956 EP16264 EP19742 FGM216C11 IP04835 IP05135 RP001003323 RP001003496 RP001003558 RP001015672 RP001020097 RP001027071 RP001040350 RP001047882 RP001054553 UT01748
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0037329 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40655
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_141283 NM_169054 RefSeq (Proteins) • NP_649540 NP_730934 DDBJ / EMBL / GenBank • AAF52026 AAL39247 AAN13239 AI134376 AW940427 AY069102 CL526049 Entrez Gene - A searchable database of RefSeq genes. • 40655 UniProtKB/TrEMBL • Q8IPQ6 Q9VNC0
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • ApaG domain (IPR007474)
Linkouts
	BioGRID - A database of protein and genetic interactions • 65864 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0037329 DroID - A comprehensive database of gene and protein interactions. • FBgn0037329 DRSC - Results from RNAi screens. • FBgn0037329 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037329 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12162-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0037329 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40655 InParanoid A subset of ortholog calls from InParanoid. • AAEL011113-PA Aedes aegypti (mosquito) AGAP001153-PA Anopheles gambiae (mosquito) XP_001948226.1 Acyrthosiphon pisum (pea aphid) 244448 Branchiostoma floridae (lancelet) XP_001896723.1 Brugia malayi (roundworm nematode) BGIBMGA013121-PA Bombyx mori (silk worm) ENSBTAP00000010675 Bos taurus (bovine) CN27906 Caenorhabditis brenneri (small nematode) CBP26844 Caenorhabditis briggsae (nematode) CE37465 Caenorhabditis elegans (worm) ENSCAFP00000027538 Canis familiaris (dog) ENSCINP00000016033 Ciona intestinalis (sea squirt) JA01907 Caenorhabditis japonica (nematode) CPIJ013390 Culex pipens (mosquito) ENSCPOP00000002859 Cavia porcellus (guinea pig) RP36232 Caenorhabditis remanei (nematode) ENSCSAVP00000011862 Ciona savignyi (sedentary tunicate) 164871 Capitella spl (polychaete worm) 203725 Daphnia pulex (daphnia) ENSDARP00000072478 Danio rerio (zebra fish) ENSECAP00000011943 Equus caballus (horse) ENSGACP00000007163 Gymnopilus aculeatus (mushroom) ENSGALP00000005078 Gallus gallus (chicken) 114796 Hypsipyla robusta (cedar shoot borer) ENSP00000003607 Homo sapiens (human) ISCW009788-PA Ixodes scapularis (deer tick) 121872 Lottia gigantea (owl limpet) 26103 Monocosta brevicollis (choanoflagellate) ENSMODP00000024011 Monodelphis domestica (gray opossum) ENSMMUP00000025165 Macaca mulatta (rhesus monkey) ENSMUSP00000001127 Mus musculus (house mouse) 175505 Nematostella vectensis (starlet anemone) XP_001599719.1 Nasonia vitripennis (wasp) ENSOANP00000024609 Ornithorynchus anatinus (platypus) ENSORLP00000012315 Oryzias latipes (japanese killifish) PHUM009901-PA Pediculus humanus (human body louse) PP07816 Pristionchus pacificus (nematode) 224718 Physcomitrella patens (moss) ENSPPYP00000009096 Pongo pygmaeus (orangutan) ENSPTRP00000015214 Pan troglodytes (chimpanzee) ENSRNOP00000013100 Rattus norvegicus (norway rat) 5060187 Sorghum bicolor (sorghum) Smp_024500.1 Schistosoma mansoni (trematode parasite) XP_001194865.1 Strongylocentrotus purpuratus (purple sea urchin) 58326 Trichoplax adhaerens (metazoa) XP_966471.1 Tribolium castaneum (red flour beetle) Tc00.1047053507515.80 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053508211.70 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000017301 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000027796 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000051302 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40655 modMine - Data generated by the modENCODE project. • FBgn0037329 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB15118 NV15451 LH24191 ISCW009788 FBgn0242537 FBgn0213235 FBgn0209802 FBgn0191276 FBgn0165755 JGI_V11_203725 FBgn0071497 FBgn0159257 FBgn0145805 FBgn0126062 FBgn0105103 FBgn0094271 CPIJ013390 BGIBMGA013121 ACYPI006884 GB10300 AGAP001153 AAEL011113 PHUM455680 GLEAN_14911
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG12162 (Svensson et al., 2007, Keleman et al., 2009.8.5, Cammarato et al., 2011)
Name Synonym
Secondary FlyBase IDs
References ( 10 )
Research paper	Svensson et al., 2007, Dev. Genes Evol. 217(9): 639--650 Organization and regulation of sex-specific thioredoxin encoding genes in the genus Drosophila. [FBrf0201263]
Supplementary material	Cammarato et al., 2011, PLoS ONE 6(4): Table S1. Proteins & Peptides. [FBrf0214682] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]