Gene model reviewed during 5.47
Low-frequency RNA-Seq exon junction(s) not annotated.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\jagn using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\jagn in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: jagn CG10978
Identification: In a study of lethal mutations that in germ line clones cause a defect in nurse cell cytoplasm transport during oogenesis.
jagn causes a defect in the oocyte structure after stage 10. The anterior region of mutant oocytes becomes detached from adjacent nurse cells and follicle cells. The phenotype begins to appear during stage 10 and becomes severe as the oocyte begins to grow rapidly during stage 11, resulting in small eggs. In jagn mutant oocytes, the movement of anterior cytoplasm is defective in stage 10A and jagn ooplasm fails to shift direction to form a whirlpool during stage 10B. exu-containing particle movement is defective in the jagn germline clones. Both macrochaetes and microchaetes formed in jagn clones are short and thin. The jagn macrochaetes are structurally unstable and easily detached. Clones of jagn mutation also cause defects in eye development and follicle cell morphogenesis.