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Gene Dmel\CG2017

General Information
Symbol	Dmel\CG2017	Species	D. melanogaster
Name		Annotation symbol	CG2017
Feature type	protein_coding_gene	FlyBase ID	FBgn0037391
Gene Model Status	Current	Stock availability	10 publicly available
Also Known As	CG 2017
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	83C5-83C6	Sequence location	3R:1,683,799..1,688,133 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG2017 (FBgn0037391). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: GTP binding. The biological processes in which it is involved are not known. 11 alleles are reported. The phenotype of these alleles is annotated with: intersegmental nerve. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Protein synthesis factor, GTP-binding; Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal; Translation elongation/initiation factor/Ribosomal, beta-barrel. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during late pupal stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult central nervous system, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male reproductive system. Comments on Affy2 ProbeSet: ProbeSet 1633771_s_at completely aligns to an exonic region common to each of the 5 FlyBase-annotated transcript isoforms of CG2017. Gene sequence location is 3R:1683799..1688133.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	References Antosh et al., 2011, Aging 3(6): 576--583 Sequence features HFA12293 BKN21672
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 83C5-83C6   Limits computationally determined from genome sequence between P{lacW}casj1C2 and P{PZ}lab01241
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG2017 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG2017-RA FBtr0078661  NM_141346   2301   643 CG2017-RB FBtr0078664  NM_169115   2374   604 CG2017-RC FBtr0078663  NM_169116   2215   604 CG2017-RD FBtr0078662  NM_169117   2083   604 CG2017-RE FBtr0114518  NM_001144540   2150   604
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG2017-PA   FBpp0078310   70.3   643   5.48     NP_649603   AAF51935 CG2017-PB   FBpp0078313   65.8   604   5.37     NP_731024   AAF51934 CG2017-PC   FBpp0078312   65.8   604   5.37     NP_731025   AAF51936 CG2017-PD   FBpp0078311   65.8   604   5.37     NP_731026   AAN14330 CG2017-PE   FBpp0113010   65.8   604   5.37     NP_001138012   ACL83471
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Protein synthesis factor, GTP-binding (IPR000795) Translation elongation/initiation factor/Ribosomal, beta-barrel (IPR009000) Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal (IPR009001)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA142224   AA142225   AA246811   AA820311   AA952174   AE014297 AAF51934   AE014297 AAF51935   AE014297 AAF51936   AE014297 AAN14330   AE014297 ACL83471   AI064156   AI109447   AI259387   AI296481   AI403381   AI532218   AI541730   AI542807   AQ072974   AW944320   AY052084 AAK93508   BF490296   BF492469   BF494926   BF495495   BF496540   BF496750   BF497572   BF498116   BF501308   BF502670   BG631972   BG632160   BG633228   BG634298   BG635150   BG638381   BI170185   BI171015   BI173361   BI241966   BI370416   BI372189   BI375932   BI563504   BI563749   BI564519   BI567344   BI569441   BI569677   BI570853   BI570883   BI572965   BI572976   BI573737   BI573738   BI575183   BI575470   BI578296   BI581009   BI581010   BI582997   BI583228   BI584319   BI584331   BI584477   BI585622   BI585793   BI586784   BI586865   BI589762   BI590047   BI590102   BI590697   BI592874   BI593568   BI605574   BI605719   BI607036   BI607242   BI607517   BI608465   BI609629   BI609663   BI610039   BI610049   BI610123   BI610260   BI610302   BI610456   BI611562   BI611747   BI614978   BI616880   BI618765   BI618992   BI627108   BI629975   BI631631   BI639027   BP545751   CK131460   CK605228   CK605229   CK659045   CL527674   CL527692   CO196028   CO267010   CO286839   CO295090   CO309573   CO340918   CO344567   CZ469567   CZ469626   CZ484180   EC064499   EC207079   EC210301   EC212972   EC216962   EC237138   EC248038   EC252605   EC257101   EL883195
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q86BS2 Q960F7
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0037391    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0037391 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during late pupal stages, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0037391 expression level Developmental Stage   Expression Level embryo 00-02hr    551 embryo 02-04hr    511 embryo 04-06hr    981 embryo 06-08hr    1208 embryo 08-10hr    1020 embryo 10-12hr    888 embryo 12-14hr    745 embryo 14-16hr    1847 embryo 16-18hr    2912 embryo 18-20hr    3258 embryo 20-22hr    2060 embryo 22-24hr    2079 larva L1    1134 larva L2    622 larva L3 12hr old    1130 larva L3 puffstage 1-2    1800 larva L3 puffstage 3-6    2508 larva L3 puffstage 7-9    2667 white prepupae new    2741 white prepupae 12hr    2629 white prepupae 24hr    2065 pupae 2d postWPP    1479 pupae 3d postWPP    2084 pupae 4d postWPP    4230 adult male 01day    4779 adult male 05day    5235 adult male 30day    3571 adult female 01day    3084 adult female 05day    1170 adult female 30day    804 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (551) embryo 02-04hr  (511) embryo 04-06hr  (981) embryo 06-08hr  (1208) embryo 08-10hr  (1020) embryo 10-12hr  (888) embryo 12-14hr  (745) embryo 14-16hr  (1847) embryo 16-18hr  (2912) embryo 18-20hr  (3258) embryo 20-22hr  (2060) embryo 22-24hr  (2079) larva L1  (1134) larva L2  (622) larva L3 12hr old  (1130) larva L3 puffstage 1-2  (1800) larva L3 puffstage 3-6  (2508) larva L3 puffstage 7-9  (2667) white prepupae new  (2741) white prepupae 12hr  (2629) white prepupae 24hr  (2065) pupae 2d postWPP  (1479) pupae 3d postWPP  (2084) pupae 4d postWPP  (4230) adult male 01day  (4779) adult male 05day  (5235) adult male 30day  (3571) adult female 01day  (3084) adult female 05day  (1170) adult female 30day  (804) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    551 embryo 02-04hr    511 embryo 04-06hr    981 embryo 06-08hr    1208 embryo 08-10hr    1020 embryo 10-12hr    888 embryo 12-14hr    745 embryo 14-16hr  (1847) embryo 16-18hr  (2912) embryo 18-20hr  (3258) embryo 20-22hr  (2060) embryo 22-24hr  (2079) larva L1    1134 larva L2    622 larva L3 12hr old    1130 larva L3 puffstage 1-2  (1800) larva L3 puffstage 3-6  (2508) larva L3 puffstage 7-9  (2667) white prepupae new  (2741) white prepupae 12hr  (2629) white prepupae 24hr  (2065) pupae 2d postWPP  1479 pupae 3d postWPP  (2084) pupae 4d postWPP  (4230) adult male 01day  (4779) adult male 05day  (5235) adult male 30day  (3571) adult female 01day  (3084) adult female 05day    1170 adult female 30day    804 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    551 embryo 02-04hr    511 embryo 04-06hr    981 embryo 06-08hr    1208 embryo 08-10hr    1020 embryo 10-12hr    888 embryo 12-14hr    745 embryo 14-16hr    1847 embryo 16-18hr    2912 embryo 18-20hr    3258 embryo 20-22hr    2060 embryo 22-24hr    2079 larva L1    1134 larva L2    622 larva L3 12hr old    1130 larva L3 puffstage 1-2    1800 larva L3 puffstage 3-6    2508 larva L3 puffstage 7-9    2667 white prepupae new    2741 white prepupae 12hr    2629 white prepupae 24hr    2065 pupae 2d postWPP    1479 pupae 3d postWPP    2084 pupae 4d postWPP    4230 adult male 01day    4779 adult male 05day    5235 adult male 30day    3571 adult female 01day    3084 adult female 05day    1170 adult female 30day    804 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    551 embryo 02-04hr    511 embryo 04-06hr    981 embryo 06-08hr    1208 embryo 08-10hr    1020 embryo 10-12hr    888 embryo 12-14hr    745 embryo 14-16hr    1847 embryo 16-18hr    2912 embryo 18-20hr    3258 embryo 20-22hr    2060 embryo 22-24hr    2079 larva L1    1134 larva L2    622 larva L3 12hr old    1130 larva L3 puffstage 1-2    1800 larva L3 puffstage 3-6    2508 larva L3 puffstage 7-9    2667 white prepupae new    2741 white prepupae 12hr    2629 white prepupae 24hr    2065 pupae 2d postWPP    1479 pupae 3d postWPP    2084 pupae 4d postWPP    4230 adult male 01day    4779 adult male 05day    5235 adult male 30day    3571 adult female 01day    3084 adult female 05day    1170 adult female 30day    804 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0037391 expression level Developmental Stage   Expression Level embryo 00-02hr    551 embryo 02-04hr    511 embryo 04-06hr    981 embryo 06-08hr    1208 embryo 08-10hr    1020 embryo 10-12hr    888 embryo 12-14hr    745 embryo 14-16hr    1847 embryo 16-18hr    2912 embryo 18-20hr    3258 embryo 20-22hr    2060 embryo 22-24hr    2079 larva L1    1134 larva L2    622 larva L3 12hr old    1130 larva L3 puffstage 1-2    1800 larva L3 puffstage 3-6    2508 larva L3 puffstage 7-9    2667 white prepupae new    2741 white prepupae 12hr    2629 white prepupae 24hr    2065 pupae 2d postWPP    1479 pupae 3d postWPP    2084 pupae 4d postWPP    4230 adult male 01day    4779 adult male 05day    5235 adult male 30day    3571 adult female 01day    3084 adult female 05day    1170 adult female 30day    804 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (551) embryo 02-04hr  (511) embryo 04-06hr  (981) embryo 06-08hr  (1208) embryo 08-10hr  (1020) embryo 10-12hr  (888) embryo 12-14hr  (745) embryo 14-16hr  (1847) embryo 16-18hr  (2912) embryo 18-20hr  (3258) embryo 20-22hr  (2060) embryo 22-24hr  (2079) larva L1  (1134) larva L2  (622) larva L3 12hr old  (1130) larva L3 puffstage 1-2  (1800) larva L3 puffstage 3-6  (2508) larva L3 puffstage 7-9  (2667) white prepupae new  (2741) white prepupae 12hr  (2629) white prepupae 24hr  (2065) pupae 2d postWPP  (1479) pupae 3d postWPP  (2084) pupae 4d postWPP  (4230) adult male 01day  (4779) adult male 05day  (5235) adult male 30day  (3571) adult female 01day  (3084) adult female 05day  (1170) adult female 30day  (804) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    551 embryo 02-04hr    511 embryo 04-06hr    981 embryo 06-08hr    1208 embryo 08-10hr    1020 embryo 10-12hr    888 embryo 12-14hr    745 embryo 14-16hr  1847 embryo 16-18hr  (2912) embryo 18-20hr  (3258) embryo 20-22hr  2060 embryo 22-24hr  2079 larva L1    1134 larva L2    622 larva L3 12hr old    1130 larva L3 puffstage 1-2  1800 larva L3 puffstage 3-6  (2508) larva L3 puffstage 7-9  (2667) white prepupae new  (2741) white prepupae 12hr  (2629) white prepupae 24hr  2065 pupae 2d postWPP  1479 pupae 3d postWPP  2084 pupae 4d postWPP  (4230) adult male 01day  (4779) adult male 05day  (5235) adult male 30day  (3571) adult female 01day  (3084) adult female 05day    1170 adult female 30day    804 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    551 embryo 02-04hr    511 embryo 04-06hr    981 embryo 06-08hr    1208 embryo 08-10hr    1020 embryo 10-12hr    888 embryo 12-14hr    745 embryo 14-16hr    1847 embryo 16-18hr    2912 embryo 18-20hr    3258 embryo 20-22hr    2060 embryo 22-24hr    2079 larva L1    1134 larva L2    622 larva L3 12hr old    1130 larva L3 puffstage 1-2    1800 larva L3 puffstage 3-6    2508 larva L3 puffstage 7-9    2667 white prepupae new    2741 white prepupae 12hr    2629 white prepupae 24hr    2065 pupae 2d postWPP    1479 pupae 3d postWPP    2084 pupae 4d postWPP    4230 adult male 01day    4779 adult male 05day    5235 adult male 30day    3571 adult female 01day    3084 adult female 05day    1170 adult female 30day    804 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    551 embryo 02-04hr    511 embryo 04-06hr    981 embryo 06-08hr    1208 embryo 08-10hr    1020 embryo 10-12hr    888 embryo 12-14hr    745 embryo 14-16hr    1847 embryo 16-18hr    2912 embryo 18-20hr    3258 embryo 20-22hr    2060 embryo 22-24hr    2079 larva L1    1134 larva L2    622 larva L3 12hr old    1130 larva L3 puffstage 1-2    1800 larva L3 puffstage 3-6    2508 larva L3 puffstage 7-9    2667 white prepupae new    2741 white prepupae 12hr    2629 white prepupae 24hr    2065 pupae 2d postWPP    1479 pupae 3d postWPP    2084 pupae 4d postWPP    4230 adult male 01day    4779 adult male 05day    5235 adult male 30day    3571 adult female 01day    3084 adult female 05day    1170 adult female 30day    804 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0037391    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0037391 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult central nervous system, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male reproductive system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0037391 expression level Tissue   Expression Level Larval Central Nervous System    190.525 Larval Midgut    204.3 Larval Hindgut    193.2 Larval Malpighian Tubules    256.1 Larval Fat Body    160.9 Larval Salivary Gland    163.7 Larval Trachea    170.325 Larval Carcass    527.125 Adult Head    307.6 Adult Eye    383.625 Adult Brain    600.5 Adult Thoracic-Abdominal Ganglion    581.6 Adult Crop    278.1 Adult Midgut    156.6 Adult Hindgut    230.1 Adult Malpighian Tubules    201.5 Adult Fat Body    99.6 Adult Salivary Gland    258.5 Adult Heart    188.525 Adult VirginFemale Spermatheca    189.1 Adult InseminatedFemale Spermatheca    172.2 Adult Ovary    59.4 Adult Testis    368.7 Adult Male Accessory Gland    155.9 Adult Carcass    591.2 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    190.525 Larval Midgut    204.3 Larval Hindgut    193.2 Larval Malpighian Tubules    256.1 Larval Fat Body    160.9 Larval Salivary Gland    163.7 Larval Trachea    170.325 Larval Carcass  527.125 Adult Head    307.6 Adult Eye    383.625 Adult Brain  (600.5) Adult Thoracic-Abdominal Ganglion  (581.6) Adult Crop    278.1 Adult Midgut    156.6 Adult Hindgut    230.1 Adult Malpighian Tubules    201.5 Adult Fat Body    99.6 Adult Salivary Gland    258.5 Adult Heart    188.525 Adult VirginFemale Spermatheca    189.1 Adult InseminatedFemale Spermatheca    172.2 Adult Ovary    59.4 Adult Testis    368.7 Adult Male Accessory Gland    155.9 Adult Carcass  (591.2) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    190.525 Larval Midgut    204.3 Larval Hindgut    193.2 Larval Malpighian Tubules    256.1 Larval Fat Body    160.9 Larval Salivary Gland    163.7 Larval Trachea    170.325 Larval Carcass    527.125 Adult Head    307.6 Adult Eye    383.625 Adult Brain    600.5 Adult Thoracic-Abdominal Ganglion    581.6 Adult Crop    278.1 Adult Midgut    156.6 Adult Hindgut    230.1 Adult Malpighian Tubules    201.5 Adult Fat Body    99.6 Adult Salivary Gland    258.5 Adult Heart    188.525 Adult VirginFemale Spermatheca    189.1 Adult InseminatedFemale Spermatheca    172.2 Adult Ovary    59.4 Adult Testis    368.7 Adult Male Accessory Gland    155.9 Adult Carcass    591.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    190.525 Larval Midgut    204.3 Larval Hindgut    193.2 Larval Malpighian Tubules    256.1 Larval Fat Body    160.9 Larval Salivary Gland    163.7 Larval Trachea    170.325 Larval Carcass    527.125 Adult Head    307.6 Adult Eye    383.625 Adult Brain    600.5 Adult Thoracic-Abdominal Ganglion    581.6 Adult Crop    278.1 Adult Midgut    156.6 Adult Hindgut    230.1 Adult Malpighian Tubules    201.5 Adult Fat Body    99.6 Adult Salivary Gland    258.5 Adult Heart    188.525 Adult VirginFemale Spermatheca    189.1 Adult InseminatedFemale Spermatheca    172.2 Adult Ovary    59.4 Adult Testis    368.7 Adult Male Accessory Gland    155.9 Adult Carcass    591.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0037391 expression level Tissue   Expression Level Larval Central Nervous System    190.525 Larval Midgut    204.3 Larval Hindgut    193.2 Larval Malpighian Tubules    256.1 Larval Fat Body    160.9 Larval Salivary Gland    163.7 Larval Trachea    170.325 Larval Carcass    527.125 Adult Head    307.6 Adult Eye    383.625 Adult Brain    600.5 Adult Thoracic-Abdominal Ganglion    581.6 Adult Crop    278.1 Adult Midgut    156.6 Adult Hindgut    230.1 Adult Malpighian Tubules    201.5 Adult Fat Body    99.6 Adult Salivary Gland    258.5 Adult Heart    188.525 Adult VirginFemale Spermatheca    189.1 Adult InseminatedFemale Spermatheca    172.2 Adult Ovary    59.4 Adult Testis    368.7 Adult Male Accessory Gland    155.9 Adult Carcass    591.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    190.525 Larval Midgut    204.3 Larval Hindgut    193.2 Larval Malpighian Tubules    256.1 Larval Fat Body    160.9 Larval Salivary Gland    163.7 Larval Trachea    170.325 Larval Carcass  527.125 Adult Head    307.6 Adult Eye    383.625 Adult Brain  600.5 Adult Thoracic-Abdominal Ganglion  581.6 Adult Crop    278.1 Adult Midgut    156.6 Adult Hindgut    230.1 Adult Malpighian Tubules    201.5 Adult Fat Body    99.6 Adult Salivary Gland    258.5 Adult Heart    188.525 Adult VirginFemale Spermatheca    189.1 Adult InseminatedFemale Spermatheca    172.2 Adult Ovary    59.4 Adult Testis    368.7 Adult Male Accessory Gland    155.9 Adult Carcass  591.2 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    190.525 Larval Midgut    204.3 Larval Hindgut    193.2 Larval Malpighian Tubules    256.1 Larval Fat Body    160.9 Larval Salivary Gland    163.7 Larval Trachea    170.325 Larval Carcass    527.125 Adult Head    307.6 Adult Eye    383.625 Adult Brain    600.5 Adult Thoracic-Abdominal Ganglion    581.6 Adult Crop    278.1 Adult Midgut    156.6 Adult Hindgut    230.1 Adult Malpighian Tubules    201.5 Adult Fat Body    99.6 Adult Salivary Gland    258.5 Adult Heart    188.525 Adult VirginFemale Spermatheca    189.1 Adult InseminatedFemale Spermatheca    172.2 Adult Ovary    59.4 Adult Testis    368.7 Adult Male Accessory Gland    155.9 Adult Carcass    591.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    190.525 Larval Midgut    204.3 Larval Hindgut    193.2 Larval Malpighian Tubules    256.1 Larval Fat Body    160.9 Larval Salivary Gland    163.7 Larval Trachea    170.325 Larval Carcass    527.125 Adult Head    307.6 Adult Eye    383.625 Adult Brain    600.5 Adult Thoracic-Abdominal Ganglion    581.6 Adult Crop    278.1 Adult Midgut    156.6 Adult Hindgut    230.1 Adult Malpighian Tubules    201.5 Adult Fat Body    99.6 Adult Salivary Gland    258.5 Adult Heart    188.525 Adult VirginFemale Spermatheca    189.1 Adult InseminatedFemale Spermatheca    172.2 Adult Ovary    59.4 Adult Testis    368.7 Adult Male Accessory Gland    155.9 Adult Carcass    591.2 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    307.6   NA  Eye    383.625   NA  Brain    600.5   190.525  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    581.6   NA  Crop    278.1   204.3  Midgut    156.6   193.2  Hindgut    230.1   256.1  Malpighian Tubules    201.5   160.9  Fat Body    99.6   163.7  Salivary Gland    258.5   NA  Heart    188.525   170.325  Trachea    NA   NA  VirginFemale Spermatheca    189.1   NA  InseminatedFemale Spermatheca    172.2   NA  Ovary    59.4   NA  Testis    368.7   NA  Male Accessory Gland    155.9   527.125  Carcass    591.2 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_24
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037391 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG2017-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG2017EY00284 CG2017EY03010 viable, with Scer\GAL4pnr-MD237 CG2017GD9704 Sterility Allele fertile CG2017EY00284 CG2017EY03010 Other Phenotypes Allele neuroanatomy defective | larval stage, with Scer\GAL4elav-C155 CG2017EP3503 Phenotype manifest in Allele anterior fascicle & synapse, with Scer\GAL4elav-C155 CG2017EP3503 intersegmental nerve, with Scer\GAL4elav-C155 CG2017EP3503
Classical Alleles ( 8 )
For All Classical Alleles Show
Allele of CG2017 Class Mutagen Stocks Known lesion CG2017c04865 piggyBac transposase 1 -- CG2017c04940 piggyBac transposase 1 -- CG2017EY00284 P-element activity 1 -- CG2017EY03010 P-element activity 1 -- CG2017f01712 piggyBac transposase 1 -- CG2017MI03061 1 -- CG2017NP5415 1 -- CG2017EP3503 P-element activity 0 Yes
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG2017 Class Mutagen Stocks Known lesion CG2017GD9704 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG2017HMS00976 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG2017KK101621 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel7284 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD9704} NA P{KK101621} NA P{TRiP.HMS00976} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}CG2017EP3503 NA P{EPgy2}CG2017EY00284 NA P{EPgy2}CG2017EY03010 NA miscellaneous insertions Mi{MIC}CG2017MI03061 NA PBac{PB}CG2017c04865 NA PBac{PB}CG2017c04940 NA PBac{WH}CG2017f01712 NA insertion of enhancer trap binary system P{GawB}CG2017NP5415 No
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
GTPase activity inferred from electronic annotation with InterPro:IPR000795 (FlyBase Curators et al., 2004-) GTP binding inferred from sequence or structural similarity with EMBL:U87965 (FlyBase, 1992-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG2017 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 65937 DroID - A comprehensive database of gene and protein interactions. • FBgn0037391 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40733
Orthologs
Genome-wide drosophilid orthologs	Dana\GF18641 Dere\GG10776 Dgri\GH18709 Dmoj\GI22855 Dper\GL23496 Dpse\GA15187 Dsec\GM10584 Dsim\GD19575 Dvir\GJ14157 Dwil\GK14220 Dyak\GE24131
Curated drosophilid orthologs	Dpse\GA15187
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL005071-PA Aedes aegypti (mosquito) AGAP005294-PB Anopheles gambiae (mosquito) XP_394725.2 Apis mellifera (honey bee) XP_001947939.1 Acyrthosiphon pisum (pea aphid) 33882 Batrachochytrium dendrobatidis (chytrid fungus) 278061 Branchiostoma floridae (lancelet) BGIBMGA011993-PA Bombyx mori (silk worm) ENSBTAP00000007903 Bos taurus (bovine) CN10610 Caenorhabditis brenneri (small nematode) CBP35318 Caenorhabditis briggsae (nematode) CE13169 Caenorhabditis elegans (worm) ENSCAFP00000002822 Canis familiaris (dog) JA09175 Caenorhabditis japonica (nematode) CPIJ003636 Culex pipens (mosquito) ENSCPOP00000015156 Cavia porcellus (guinea pig) RP32455 Caenorhabditis remanei (nematode) ENSCSAVP00000019180 Ciona savignyi (sedentary tunicate) 18841 Capitella spl (polychaete worm) 313245 Daphnia pulex (daphnia) ENSDARP00000060027 Danio rerio (zebra fish) ENSDARP00000095598 Danio rerio (zebra fish) ENSECAP00000022563 Equus caballus (horse) ENSGACP00000011907 Gymnopilus aculeatus (mushroom) ENSGALP00000016774 Gallus gallus (chicken) ENSP00000303997 Homo sapiens (human) ISCW015120-PA Ixodes scapularis (deer tick) 159869 Lottia gigantea (owl limpet) ENSMODP00000023655 Monodelphis domestica (gray opossum) ENSMMUP00000011670 Macaca mulatta (rhesus monkey) ENSMUSP00000024748 Mus musculus (house mouse) 197733 Nematostella vectensis (starlet anemone) XP_001599526.1 Nasonia vitripennis (wasp) ENSORLP00000008168 Oryzias latipes (japanese killifish) PHUM009446-PA Pediculus humanus (human body louse) PP24381 Pristionchus pacificus (nematode) ENSPPYP00000019370 Pongo pygmaeus (orangutan) 79073 Phytophthora ramorum (sudden oak death pathogen) 142516 Phytophthora sojae (root rot pathogen) ENSPTRP00000031112 Pan troglodytes (chimpanzee) ENSRNOP00000026195 Rattus norvegicus (norway rat) XP_001188538.1 Strongylocentrotus purpuratus (purple sea urchin) 57326 Trichoplax adhaerens (metazoa) XP_972902.1 Tribolium castaneum (red flour beetle) ENSTNIP00000011467 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000030272 Takifugu rubripes (pufferfish Takifugu) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV18623 LH24532 ISCW015120 FBgn0241267 FBgn0216226 FBgn0201375 FBgn0191068 FBgn0165530 JGI_V11_313245 FBgn0075212 FBgn0161086 FBgn0145582 FBgn0126176 FBgn0103081 FBgn0095659 CPIJ003636 ACYPI005221 GB16527 AGAP005294 AAEL005071 PB24711 PHUM418730 GLEAN_10866
Stocks & Reagents
Stocks Listed in FlyBase ( 10 )
Bloomington	36186 y1 w*; Mi{MIC}CG2017MI03061 16536 y1 w67c23; P{EPgy2}CG2017EY00284 16547 y1 w67c23; P{EPgy2}CG2017EY03010 34097 y1 sc* v1; P{TRiP.HMS00976}attP2
Harvard	- PBac{PB}CG2017c04865 - PBac{PB}CG2017c04940 - PBac{WH}CG2017f01712
Kyoto	104999 y* w*; P{GawB}CG2017NP5415 / TM6, P{UAS-lacZ.UW23-1}UW23-1
VDRC	v107015 P{KK101621}VIE-260B v20780 w1118; P{GD9704}v20780
Genomic Clones ( 1 )
	BACR23H21 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 99 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	SD03629
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT01002 AT03711 AT04437 AT10308 AT10658 AT11769 AT12480 AT16592 AT18467 AT26631 AT26771 AT30457 AT31642 GH08653 GH22807 LD05984 LD29258 LP02786 LP04692 LP10407 LP16486 RE11563 RE12665 RE16263 RE39173 RE56925 RE59082 RE63838 RE72147 RH01508 RH01801 RH03247 RH03603 RH03674 RH04353 RH05645 RH05669 RH08541 RH08553 RH10677 RH11675 RH13016 RH14434 RH14473 RH14907 RH14918 RH15018 RH15352 RH15433 RH15945 RH17894 RH18146 RH21429 RH21770 RH23475 RH23509 RH23693 RH25243 RH25465 RH26883 RH26977 RH28471 RH31141 RH34147 RH34445 RH37482 RH44485 RH47007 RH49668 RH49949 RH58923 RH61247 RH61821 RH68318 RH71374 RH71605 RH74018 RH74262 RH74596 SD06790 SD09272 SD21459
Other clones	CK00088 EK000229 EK064031 EK148335 EK208620 EK218433 EP11555 EP19522 FGC033A12 GH04432 GH22736 IP12910 LD23866 RH01042 RH09267 UT01771
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0037391 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40733
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_141346 NM_169115 NM_169116 NM_169117 NM_001144540 RefSeq (Proteins) • NP_649603 NP_731024 NP_731025 NP_731026 NP_001138012 DDBJ / EMBL / GenBank • AAF51934 AAF51935 AAF51936 AAK93508 AAN14330 ACL83471 AI532218 AQ072974 AW944320 AY052084 CL527674 CL527692 CZ469567 CZ469626 CZ484180 Entrez Gene - A searchable database of RefSeq genes. • 40733 UniProtKB/TrEMBL • Q86BS2 Q960F7
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Protein synthesis factor, GTP-binding (IPR000795) Translation elongation/initiation factor/Ribosomal, beta-barrel (IPR009000) Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal (IPR009001)
Linkouts
	BioGRID - A database of protein and genetic interactions • 65937 DroID - A comprehensive database of gene and protein interactions. • FBgn0037391 DRSC - Results from RNAi screens. • FBgn0037391 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037391 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG2017-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0037391 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40733 InParanoid A subset of ortholog calls from InParanoid. • AAEL005071-PA Aedes aegypti (mosquito) AGAP005294-PB Anopheles gambiae (mosquito) XP_394725.2 Apis mellifera (honey bee) XP_001947939.1 Acyrthosiphon pisum (pea aphid) 33882 Batrachochytrium dendrobatidis (chytrid fungus) 278061 Branchiostoma floridae (lancelet) BGIBMGA011993-PA Bombyx mori (silk worm) ENSBTAP00000007903 Bos taurus (bovine) CN10610 Caenorhabditis brenneri (small nematode) CBP35318 Caenorhabditis briggsae (nematode) CE13169 Caenorhabditis elegans (worm) ENSCAFP00000002822 Canis familiaris (dog) JA09175 Caenorhabditis japonica (nematode) CPIJ003636 Culex pipens (mosquito) ENSCPOP00000015156 Cavia porcellus (guinea pig) RP32455 Caenorhabditis remanei (nematode) ENSCSAVP00000019180 Ciona savignyi (sedentary tunicate) 18841 Capitella spl (polychaete worm) 313245 Daphnia pulex (daphnia) ENSDARP00000060027 Danio rerio (zebra fish) ENSDARP00000095598 Danio rerio (zebra fish) ENSECAP00000022563 Equus caballus (horse) ENSGACP00000011907 Gymnopilus aculeatus (mushroom) ENSGALP00000016774 Gallus gallus (chicken) ENSP00000303997 Homo sapiens (human) ISCW015120-PA Ixodes scapularis (deer tick) 159869 Lottia gigantea (owl limpet) ENSMODP00000023655 Monodelphis domestica (gray opossum) ENSMMUP00000011670 Macaca mulatta (rhesus monkey) ENSMUSP00000024748 Mus musculus (house mouse) 197733 Nematostella vectensis (starlet anemone) XP_001599526.1 Nasonia vitripennis (wasp) ENSORLP00000008168 Oryzias latipes (japanese killifish) PHUM009446-PA Pediculus humanus (human body louse) PP24381 Pristionchus pacificus (nematode) ENSPPYP00000019370 Pongo pygmaeus (orangutan) 79073 Phytophthora ramorum (sudden oak death pathogen) 142516 Phytophthora sojae (root rot pathogen) ENSPTRP00000031112 Pan troglodytes (chimpanzee) ENSRNOP00000026195 Rattus norvegicus (norway rat) XP_001188538.1 Strongylocentrotus purpuratus (purple sea urchin) 57326 Trichoplax adhaerens (metazoa) XP_972902.1 Tribolium castaneum (red flour beetle) ENSTNIP00000011467 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000030272 Takifugu rubripes (pufferfish Takifugu) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40733 modMine - Data generated by the modENCODE project. • FBgn0037391 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV18623 LH24532 ISCW015120 FBgn0241267 FBgn0216226 FBgn0201375 FBgn0191068 FBgn0165530 JGI_V11_313245 FBgn0075212 FBgn0161086 FBgn0145582 FBgn0126176 FBgn0103081 FBgn0095659 CPIJ003636 ACYPI005221 GB16527 AGAP005294 AAEL005071 PB24711 PHUM418730 GLEAN_10866
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	CG 2017 (Kraut et al., 2001, Kraut et al., 2001) CG2017 (Gruenewald et al., 2009, Akdemir et al., 2007, Raymond et al., 2004, Keleman et al., 2009.8.5, Ni et al., 2010.12.1)
Name Synonym	GP-1 related (Kraut et al., 2001, Kraut et al., 2001)
Secondary FlyBase IDs
References ( 21 )
Generate a list of	All references relating to this gene ( 21 )
List References by type	Research paper  ( 5 ) Supplementary material  ( 4 ) Personal communication to FlyBase  ( 6 ) FlyBase analysis  ( 2 ) Computer file  ( 3 )
Recent research papers ( 1 )
	Antosh et al., 2011, Aging 3(6): 576--583 New comparative genomics approach reveals a conserved health span signature across species. [FBrf0216594] Show all research papers ...