Gene Dmel\CG1021

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General Information

Symbol

Dmel\CG1021

Species

D. melanogaster

Name

Annotation symbol

CG1021

Feature type

protein_coding_gene

FlyBase ID

FBgn0037443

Gene Model Status

Current

Stock availability

11 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

83E5-83E6

Sequence location

3R:2,214,884..2,231,617 [-]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG1021 (FBgn0037443). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 12 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Predicted transmembrane/coiled-coil 2 protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult eye, adult heart, adult fat body, adult spermathecae. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval fat body, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1629077_s_at completely aligns to an exonic region common to each of the 5 FlyBase-annotated transcript isoforms of CG1021. Gene sequence location is 3R:2214884..2231617.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

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Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

83E5-83E6

Limits computationally determined from genome sequence between P{lacW}cas^j1C2 and P{PZ}lab⁰¹²⁴¹

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG1021 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Gene model reviewed during 5.47

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG1021-RD

FBtr0289939

NM_169141

3827

638

CG1021-RE

FBtr0289940

NM_141397

3463

638

CG1021-RF

FBtr0290326

NM_001144543

3747

638

CG1021-RG

FBtr0290327

NM_001144544

2992

500

CG1021-RH

FBtr0300261

NM_001170060

2928

679

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG1021-PD

FBpp0288377

67.8

638

9.22

NP_731081

AAF54123

CG1021-PE

FBpp0288378

67.8

638

9.22

NP_649654

AAN13377

CG1021-PF

FBpp0288765

67.8

638

9.22

NP_001138015

ACL83474

CG1021-PG

FBpp0288766

54.6

500

7.62

NP_001138016

ACL83475

CG1021-PH

FBpp0289489

72.2

679

9.60

NP_001163531

ACZ94829

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Predicted transmembrane/coiled-coil 2 protein (IPR019394)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult eye, adult heart, adult fat body, adult spermathecae. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval fat body, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland, larval/adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		315.475
Larval Midgut		278.1
Larval Hindgut		313.7
Larval Malpighian Tubules		463.9
Larval Fat Body		434.7
Larval Salivary Gland		167.2
Larval Trachea		193.025
Larval Carcass		209.025
Adult Head		412.2
Adult Eye		553.65
Adult Brain		464.3
Adult Thoracic-Abdominal Ganglion		387.1
Adult Crop		300.6
Adult Midgut		272.4
Adult Hindgut		189.2
Adult Malpighian Tubules		183.4
Adult Fat Body		941.1
Adult Salivary Gland		293.8
Adult Heart		665.875
Adult VirginFemale Spermatheca		814
Adult InseminatedFemale Spermatheca		878.8
Adult Ovary		401
Adult Testis		76.1
Adult Male Accessory Gland		332.8
Adult Carcass		479.7
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		315.475
Larval Midgut		278.1
Larval Hindgut		313.7
Larval Malpighian Tubules		463.9
Larval Fat Body		434.7
Larval Salivary Gland		167.2
Larval Trachea		193.025
Larval Carcass		209.025
Adult Head		412.2
Adult Eye		(553.65)
Adult Brain		464.3
Adult Thoracic-Abdominal Ganglion		387.1
Adult Crop		300.6
Adult Midgut		272.4
Adult Hindgut		189.2
Adult Malpighian Tubules		183.4
Adult Fat Body		(941.1)
Adult Salivary Gland		293.8
Adult Heart		(665.875)
Adult VirginFemale Spermatheca		(814)
Adult InseminatedFemale Spermatheca		(878.8)
Adult Ovary		401
Adult Testis		76.1
Adult Male Accessory Gland		332.8
Adult Carcass		479.7
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		315.475
Larval Midgut		278.1
Larval Hindgut		313.7
Larval Malpighian Tubules		463.9
Larval Fat Body		434.7
Larval Salivary Gland		167.2
Larval Trachea		193.025
Larval Carcass		209.025
Adult Head		412.2
Adult Eye		553.65
Adult Brain		464.3
Adult Thoracic-Abdominal Ganglion		387.1
Adult Crop		300.6
Adult Midgut		272.4
Adult Hindgut		189.2
Adult Malpighian Tubules		183.4
Adult Fat Body		941.1
Adult Salivary Gland		293.8
Adult Heart		665.875
Adult VirginFemale Spermatheca		814
Adult InseminatedFemale Spermatheca		878.8
Adult Ovary		401
Adult Testis		76.1
Adult Male Accessory Gland		332.8
Adult Carcass		479.7
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		315.475
Larval Midgut		278.1
Larval Hindgut		313.7
Larval Malpighian Tubules		463.9
Larval Fat Body		434.7
Larval Salivary Gland		167.2
Larval Trachea		193.025
Larval Carcass		209.025
Adult Head		412.2
Adult Eye		553.65
Adult Brain		464.3
Adult Thoracic-Abdominal Ganglion		387.1
Adult Crop		300.6
Adult Midgut		272.4
Adult Hindgut		189.2
Adult Malpighian Tubules		183.4
Adult Fat Body		941.1
Adult Salivary Gland		293.8
Adult Heart		665.875
Adult VirginFemale Spermatheca		814
Adult InseminatedFemale Spermatheca		878.8
Adult Ovary		401
Adult Testis		76.1
Adult Male Accessory Gland		332.8
Adult Carcass		479.7
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		315.475
Larval Midgut		278.1
Larval Hindgut		313.7
Larval Malpighian Tubules		463.9
Larval Fat Body		434.7
Larval Salivary Gland		167.2
Larval Trachea		193.025
Larval Carcass		209.025
Adult Head		412.2
Adult Eye		553.65
Adult Brain		464.3
Adult Thoracic-Abdominal Ganglion		387.1
Adult Crop		300.6
Adult Midgut		272.4
Adult Hindgut		189.2
Adult Malpighian Tubules		183.4
Adult Fat Body		941.1
Adult Salivary Gland		293.8
Adult Heart		665.875
Adult VirginFemale Spermatheca		814
Adult InseminatedFemale Spermatheca		878.8
Adult Ovary		401
Adult Testis		76.1
Adult Male Accessory Gland		332.8
Adult Carcass		479.7
Expression Level Scale		None Low Moderate High Very high

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		315.475
Larval Midgut		278.1
Larval Hindgut		313.7
Larval Malpighian Tubules		463.9
Larval Fat Body		434.7
Larval Salivary Gland		167.2
Larval Trachea		193.025
Larval Carcass		209.025
Adult Head		412.2
Adult Eye		553.65
Adult Brain		464.3
Adult Thoracic-Abdominal Ganglion		387.1
Adult Crop		300.6
Adult Midgut		272.4
Adult Hindgut		189.2
Adult Malpighian Tubules		183.4
Adult Fat Body		(941.1)
Adult Salivary Gland		293.8
Adult Heart		665.875
Adult VirginFemale Spermatheca		814
Adult InseminatedFemale Spermatheca		(878.8)
Adult Ovary		401
Adult Testis		76.1
Adult Male Accessory Gland		332.8
Adult Carcass		479.7
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		315.475
Larval Midgut		278.1
Larval Hindgut		313.7
Larval Malpighian Tubules		463.9
Larval Fat Body		434.7
Larval Salivary Gland		167.2
Larval Trachea		193.025
Larval Carcass		209.025
Adult Head		412.2
Adult Eye		553.65
Adult Brain		464.3
Adult Thoracic-Abdominal Ganglion		387.1
Adult Crop		300.6
Adult Midgut		272.4
Adult Hindgut		189.2
Adult Malpighian Tubules		183.4
Adult Fat Body		941.1
Adult Salivary Gland		293.8
Adult Heart		665.875
Adult VirginFemale Spermatheca		814
Adult InseminatedFemale Spermatheca		878.8
Adult Ovary		401
Adult Testis		76.1
Adult Male Accessory Gland		332.8
Adult Carcass		479.7
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		315.475
Larval Midgut		278.1
Larval Hindgut		313.7
Larval Malpighian Tubules		463.9
Larval Fat Body		434.7
Larval Salivary Gland		167.2
Larval Trachea		193.025
Larval Carcass		209.025
Adult Head		412.2
Adult Eye		553.65
Adult Brain		464.3
Adult Thoracic-Abdominal Ganglion		387.1
Adult Crop		300.6
Adult Midgut		272.4
Adult Hindgut		189.2
Adult Malpighian Tubules		183.4
Adult Fat Body		941.1
Adult Salivary Gland		293.8
Adult Heart		665.875
Adult VirginFemale Spermatheca		814
Adult InseminatedFemale Spermatheca		878.8
Adult Ovary		401
Adult Testis		76.1
Adult Male Accessory Gland		332.8
Adult Carcass		479.7
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	412.2
NA	Eye	553.65
NA	Brain	464.3
315.475	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	387.1
NA	Crop	300.6
278.1	Midgut	272.4
313.7	Hindgut	189.2
463.9	Malpighian Tubules	183.4
434.7	Fat Body	941.1
167.2	Salivary Gland	293.8
NA	Heart	665.875
193.025	Trachea	NA
NA	VirginFemale Spermatheca	814
NA	InseminatedFemale Spermatheca	878.8
NA	Ovary	401
NA	Testis	76.1
NA	Male Accessory Gland	332.8
209.025	Carcass	479.7

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		22
central nervous system, larvae L3		35
central nervous system, pupae P8		46
head, virgin 1-day female		37
head, virgin 4-day female		40
head, virgin 20-day female		25
head, mated 1-day female		37
head, mated 4-day female		39
head, mated 20-day female		27
head, mated 1-day male		49
head, mated 4-day male		46
head, mated 20-day male		43
salivary gland, larvae L3 wandering		14
salivary gland, white prepupae		305
digestive system, larvae L3 wandering		33
digestive system, 1-day adult		12
digestive system, 4-day adult		17
digestive system, 20-day adult		16
fat body, larvae L3 wandering		12
fat body, white prepupae		82
fat body, pupae P8		52
carcass, larvae L3 wandering		25
carcass, 1-day adult		31
carcass, 4-day adult		30
carcass, 20-day adult		27
ovary, virgin 4-day female		37
ovary, mated 4-day female		38
testis, mated 4-day male		4
accessory gland, mated 4-day male		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		22
central nervous system, larvae L3		(35)
central nervous system, pupae P8		(46)
head, virgin 1-day female		(37)
head, virgin 4-day female		(40)
head, virgin 20-day female		25
head, mated 1-day female		(37)
head, mated 4-day female		(39)
head, mated 20-day female		(27)
head, mated 1-day male		(49)
head, mated 4-day male		(46)
head, mated 20-day male		(43)
salivary gland, larvae L3 wandering		14
salivary gland, white prepupae		(305)
digestive system, larvae L3 wandering		(33)
digestive system, 1-day adult		12
digestive system, 4-day adult		17
digestive system, 20-day adult		16
fat body, larvae L3 wandering		12
fat body, white prepupae		(82)
fat body, pupae P8		(52)
carcass, larvae L3 wandering		25
carcass, 1-day adult		(31)
carcass, 4-day adult		(30)
carcass, 20-day adult		(27)
ovary, virgin 4-day female		(37)
ovary, mated 4-day female		(38)
testis, mated 4-day male		4
accessory gland, mated 4-day male		7
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		22
central nervous system, larvae L3		35
central nervous system, pupae P8		46
head, virgin 1-day female		37
head, virgin 4-day female		40
head, virgin 20-day female		25
head, mated 1-day female		37
head, mated 4-day female		39
head, mated 20-day female		27
head, mated 1-day male		49
head, mated 4-day male		46
head, mated 20-day male		43
salivary gland, larvae L3 wandering		14
salivary gland, white prepupae		(305)
digestive system, larvae L3 wandering		33
digestive system, 1-day adult		12
digestive system, 4-day adult		17
digestive system, 20-day adult		16
fat body, larvae L3 wandering		12
fat body, white prepupae		82
fat body, pupae P8		52
carcass, larvae L3 wandering		25
carcass, 1-day adult		31
carcass, 4-day adult		30
carcass, 20-day adult		27
ovary, virgin 4-day female		37
ovary, mated 4-day female		38
testis, mated 4-day male		4
accessory gland, mated 4-day male		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		22
central nervous system, larvae L3		35
central nervous system, pupae P8		46
head, virgin 1-day female		37
head, virgin 4-day female		40
head, virgin 20-day female		25
head, mated 1-day female		37
head, mated 4-day female		39
head, mated 20-day female		27
head, mated 1-day male		49
head, mated 4-day male		46
head, mated 20-day male		43
salivary gland, larvae L3 wandering		14
salivary gland, white prepupae		305
digestive system, larvae L3 wandering		33
digestive system, 1-day adult		12
digestive system, 4-day adult		17
digestive system, 20-day adult		16
fat body, larvae L3 wandering		12
fat body, white prepupae		82
fat body, pupae P8		52
carcass, larvae L3 wandering		25
carcass, 1-day adult		31
carcass, 4-day adult		30
carcass, 20-day adult		27
ovary, virgin 4-day female		37
ovary, mated 4-day female		38
testis, mated 4-day male		4
accessory gland, mated 4-day male		7
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		22
central nervous system, larvae L3		35
central nervous system, pupae P8		46
head, virgin 1-day female		37
head, virgin 4-day female		40
head, virgin 20-day female		25
head, mated 1-day female		37
head, mated 4-day female		39
head, mated 20-day female		27
head, mated 1-day male		49
head, mated 4-day male		46
head, mated 20-day male		43
salivary gland, larvae L3 wandering		14
salivary gland, white prepupae		305
digestive system, larvae L3 wandering		33
digestive system, 1-day adult		12
digestive system, 4-day adult		17
digestive system, 20-day adult		16
fat body, larvae L3 wandering		12
fat body, white prepupae		82
fat body, pupae P8		52
carcass, larvae L3 wandering		25
carcass, 1-day adult		31
carcass, 4-day adult		30
carcass, 20-day adult		27
ovary, virgin 4-day female		37
ovary, mated 4-day female		38
testis, mated 4-day male		4
accessory gland, mated 4-day male		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		22
central nervous system, larvae L3		(35)
central nervous system, pupae P8		(46)
head, virgin 1-day female		(37)
head, virgin 4-day female		(40)
head, virgin 20-day female		25
head, mated 1-day female		(37)
head, mated 4-day female		(39)
head, mated 20-day female		27
head, mated 1-day male		(49)
head, mated 4-day male		(46)
head, mated 20-day male		(43)
salivary gland, larvae L3 wandering		14
salivary gland, white prepupae		(305)
digestive system, larvae L3 wandering		(33)
digestive system, 1-day adult		12
digestive system, 4-day adult		17
digestive system, 20-day adult		16
fat body, larvae L3 wandering		12
fat body, white prepupae		(82)
fat body, pupae P8		(52)
carcass, larvae L3 wandering		25
carcass, 1-day adult		31
carcass, 4-day adult		30
carcass, 20-day adult		27
ovary, virgin 4-day female		(37)
ovary, mated 4-day female		(38)
testis, mated 4-day male		4
accessory gland, mated 4-day male		7
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		22
central nervous system, larvae L3		35
central nervous system, pupae P8		46
head, virgin 1-day female		37
head, virgin 4-day female		40
head, virgin 20-day female		25
head, mated 1-day female		37
head, mated 4-day female		39
head, mated 20-day female		27
head, mated 1-day male		49
head, mated 4-day male		46
head, mated 20-day male		43
salivary gland, larvae L3 wandering		14
salivary gland, white prepupae		(305)
digestive system, larvae L3 wandering		33
digestive system, 1-day adult		12
digestive system, 4-day adult		17
digestive system, 20-day adult		16
fat body, larvae L3 wandering		12
fat body, white prepupae		82
fat body, pupae P8		52
carcass, larvae L3 wandering		25
carcass, 1-day adult		31
carcass, 4-day adult		30
carcass, 20-day adult		27
ovary, virgin 4-day female		37
ovary, mated 4-day female		38
testis, mated 4-day male		4
accessory gland, mated 4-day male		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		22
central nervous system, larvae L3		35
central nervous system, pupae P8		46
head, virgin 1-day female		37
head, virgin 4-day female		40
head, virgin 20-day female		25
head, mated 1-day female		37
head, mated 4-day female		39
head, mated 20-day female		27
head, mated 1-day male		49
head, mated 4-day male		46
head, mated 20-day male		43
salivary gland, larvae L3 wandering		14
salivary gland, white prepupae		305
digestive system, larvae L3 wandering		33
digestive system, 1-day adult		12
digestive system, 4-day adult		17
digestive system, 20-day adult		16
fat body, larvae L3 wandering		12
fat body, white prepupae		82
fat body, pupae P8		52
carcass, larvae L3 wandering		25
carcass, 1-day adult		31
carcass, 4-day adult		30
carcass, 20-day adult		27
ovary, virgin 4-day female		37
ovary, mated 4-day female		38
testis, mated 4-day male		4
accessory gland, mated 4-day male		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during early pupal stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		41
embryo 02-04hr		46
embryo 04-06hr		46
embryo 06-08hr		41
embryo 08-10hr		42
embryo 10-12hr		40
embryo 12-14hr		44
embryo 14-16hr		48
embryo 16-18hr		33
embryo 18-20hr		29
embryo 20-22hr		40
embryo 22-24hr		36
larva L1		21
larva L2		16
larva L3 12hr old		14
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		22
larva L3 puffstage 7-9		45
white prepupae new		79
white prepupae 12hr		80
white prepupae 24hr		48
pupae 2d postWPP		47
pupae 3d postWPP		26
pupae 4d postWPP		24
adult male 01day		27
adult male 05day		25
adult male 30day		24
adult female 01day		29
adult female 05day		31
adult female 30day		34
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(41)
embryo 02-04hr		(46)
embryo 04-06hr		(46)
embryo 06-08hr		(41)
embryo 08-10hr		(42)
embryo 10-12hr		(40)
embryo 12-14hr		(44)
embryo 14-16hr		(48)
embryo 16-18hr		(33)
embryo 18-20hr		(29)
embryo 20-22hr		(40)
embryo 22-24hr		(36)
larva L1		21
larva L2		16
larva L3 12hr old		14
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		22
larva L3 puffstage 7-9		(45)
white prepupae new		(79)
white prepupae 12hr		(80)
white prepupae 24hr		(48)
pupae 2d postWPP		(47)
pupae 3d postWPP		26
pupae 4d postWPP		24
adult male 01day		(27)
adult male 05day		25
adult male 30day		24
adult female 01day		(29)
adult female 05day		(31)
adult female 30day		(34)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		41
embryo 02-04hr		46
embryo 04-06hr		46
embryo 06-08hr		41
embryo 08-10hr		42
embryo 10-12hr		40
embryo 12-14hr		44
embryo 14-16hr		48
embryo 16-18hr		33
embryo 18-20hr		29
embryo 20-22hr		40
embryo 22-24hr		36
larva L1		21
larva L2		16
larva L3 12hr old		14
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		22
larva L3 puffstage 7-9		45
white prepupae new		79
white prepupae 12hr		80
white prepupae 24hr		48
pupae 2d postWPP		47
pupae 3d postWPP		26
pupae 4d postWPP		24
adult male 01day		27
adult male 05day		25
adult male 30day		24
adult female 01day		29
adult female 05day		31
adult female 30day		34
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		41
embryo 02-04hr		46
embryo 04-06hr		46
embryo 06-08hr		41
embryo 08-10hr		42
embryo 10-12hr		40
embryo 12-14hr		44
embryo 14-16hr		48
embryo 16-18hr		33
embryo 18-20hr		29
embryo 20-22hr		40
embryo 22-24hr		36
larva L1		21
larva L2		16
larva L3 12hr old		14
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		22
larva L3 puffstage 7-9		45
white prepupae new		79
white prepupae 12hr		80
white prepupae 24hr		48
pupae 2d postWPP		47
pupae 3d postWPP		26
pupae 4d postWPP		24
adult male 01day		27
adult male 05day		25
adult male 30day		24
adult female 01day		29
adult female 05day		31
adult female 30day		34
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		41
embryo 02-04hr		46
embryo 04-06hr		46
embryo 06-08hr		41
embryo 08-10hr		42
embryo 10-12hr		40
embryo 12-14hr		44
embryo 14-16hr		48
embryo 16-18hr		33
embryo 18-20hr		29
embryo 20-22hr		40
embryo 22-24hr		36
larva L1		21
larva L2		16
larva L3 12hr old		14
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		22
larva L3 puffstage 7-9		45
white prepupae new		79
white prepupae 12hr		80
white prepupae 24hr		48
pupae 2d postWPP		47
pupae 3d postWPP		26
pupae 4d postWPP		24
adult male 01day		27
adult male 05day		25
adult male 30day		24
adult female 01day		29
adult female 05day		31
adult female 30day		34
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(41)
embryo 02-04hr		(46)
embryo 04-06hr		(46)
embryo 06-08hr		(41)
embryo 08-10hr		(42)
embryo 10-12hr		(40)
embryo 12-14hr		(44)
embryo 14-16hr		(48)
embryo 16-18hr		(33)
embryo 18-20hr		29
embryo 20-22hr		(40)
embryo 22-24hr		(36)
larva L1		21
larva L2		16
larva L3 12hr old		14
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		22
larva L3 puffstage 7-9		(45)
white prepupae new		(79)
white prepupae 12hr		(80)
white prepupae 24hr		(48)
pupae 2d postWPP		(47)
pupae 3d postWPP		26
pupae 4d postWPP		24
adult male 01day		27
adult male 05day		25
adult male 30day		24
adult female 01day		29
adult female 05day		31
adult female 30day		(34)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		41
embryo 02-04hr		46
embryo 04-06hr		46
embryo 06-08hr		41
embryo 08-10hr		42
embryo 10-12hr		40
embryo 12-14hr		44
embryo 14-16hr		48
embryo 16-18hr		33
embryo 18-20hr		29
embryo 20-22hr		40
embryo 22-24hr		36
larva L1		21
larva L2		16
larva L3 12hr old		14
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		22
larva L3 puffstage 7-9		45
white prepupae new		79
white prepupae 12hr		80
white prepupae 24hr		48
pupae 2d postWPP		47
pupae 3d postWPP		26
pupae 4d postWPP		24
adult male 01day		27
adult male 05day		25
adult male 30day		24
adult female 01day		29
adult female 05day		31
adult female 30day		34
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		41
embryo 02-04hr		46
embryo 04-06hr		46
embryo 06-08hr		41
embryo 08-10hr		42
embryo 10-12hr		40
embryo 12-14hr		44
embryo 14-16hr		48
embryo 16-18hr		33
embryo 18-20hr		29
embryo 20-22hr		40
embryo 22-24hr		36
larva L1		21
larva L2		16
larva L3 12hr old		14
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		22
larva L3 puffstage 7-9		45
white prepupae new		79
white prepupae 12hr		80
white prepupae 24hr		48
pupae 2d postWPP		47
pupae 3d postWPP		26
pupae 4d postWPP		24
adult male 01day		27
adult male 05day		25
adult male 30day		24
adult female 01day		29
adult female 05day		31
adult female 30day		34
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		45
Schneider line 2 Sg4		2
embryonic 1182-4H		18
embryonic GM2		14
embryonic Kc167		24
embryonic S1		23
embryonic S3		3
leg disc CME L1		4
wing disc CME-W2		3
wing disc ML-DmD8		10
wing disc ML-DmD9		12
wing disc ML-DmD16-c3		46
wing disc ML-DmD21		22
wing disc ML-DmD32		7
haltere disc ML-DmD17-c3		42
eye-antennal disc ML-DmD11		5
antennal disc ML-DmD20-c5		29
mixed discs ML-DmD4-c1		9
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		6
tumorous blood cells mbn2		33
ovary fGS/OSS		47
ovary OSC		40
ovary OSS		42
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(45)
Schneider line 2 Sg4		2
embryonic 1182-4H		18
embryonic GM2		14
embryonic Kc167		24
embryonic S1		23
embryonic S3		3
leg disc CME L1		4
wing disc CME-W2		3
wing disc ML-DmD8		10
wing disc ML-DmD9		12
wing disc ML-DmD16-c3		(46)
wing disc ML-DmD21		22
wing disc ML-DmD32		7
haltere disc ML-DmD17-c3		(42)
eye-antennal disc ML-DmD11		5
antennal disc ML-DmD20-c5		(29)
mixed discs ML-DmD4-c1		9
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		6
tumorous blood cells mbn2		(33)
ovary fGS/OSS		(47)
ovary OSC		(40)
ovary OSS		(42)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		45
Schneider line 2 Sg4		2
embryonic 1182-4H		18
embryonic GM2		14
embryonic Kc167		24
embryonic S1		23
embryonic S3		3
leg disc CME L1		4
wing disc CME-W2		3
wing disc ML-DmD8		10
wing disc ML-DmD9		12
wing disc ML-DmD16-c3		46
wing disc ML-DmD21		22
wing disc ML-DmD32		7
haltere disc ML-DmD17-c3		42
eye-antennal disc ML-DmD11		5
antennal disc ML-DmD20-c5		29
mixed discs ML-DmD4-c1		9
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		6
tumorous blood cells mbn2		33
ovary fGS/OSS		47
ovary OSC		40
ovary OSS		42
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		45
Schneider line 2 Sg4		2
embryonic 1182-4H		18
embryonic GM2		14
embryonic Kc167		24
embryonic S1		23
embryonic S3		3
leg disc CME L1		4
wing disc CME-W2		3
wing disc ML-DmD8		10
wing disc ML-DmD9		12
wing disc ML-DmD16-c3		46
wing disc ML-DmD21		22
wing disc ML-DmD32		7
haltere disc ML-DmD17-c3		42
eye-antennal disc ML-DmD11		5
antennal disc ML-DmD20-c5		29
mixed discs ML-DmD4-c1		9
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		6
tumorous blood cells mbn2		33
ovary fGS/OSS		47
ovary OSC		40
ovary OSS		42
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		45
Schneider line 2 Sg4		2
embryonic 1182-4H		18
embryonic GM2		14
embryonic Kc167		24
embryonic S1		23
embryonic S3		3
leg disc CME L1		4
wing disc CME-W2		3
wing disc ML-DmD8		10
wing disc ML-DmD9		12
wing disc ML-DmD16-c3		46
wing disc ML-DmD21		22
wing disc ML-DmD32		7
haltere disc ML-DmD17-c3		42
eye-antennal disc ML-DmD11		5
antennal disc ML-DmD20-c5		29
mixed discs ML-DmD4-c1		9
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		6
tumorous blood cells mbn2		33
ovary fGS/OSS		47
ovary OSC		40
ovary OSS		42
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(45)
Schneider line 2 Sg4		2
embryonic 1182-4H		18
embryonic GM2		14
embryonic Kc167		24
embryonic S1		23
embryonic S3		3
leg disc CME L1		4
wing disc CME-W2		3
wing disc ML-DmD8		10
wing disc ML-DmD9		12
wing disc ML-DmD16-c3		(46)
wing disc ML-DmD21		22
wing disc ML-DmD32		7
haltere disc ML-DmD17-c3		(42)
eye-antennal disc ML-DmD11		5
antennal disc ML-DmD20-c5		29
mixed discs ML-DmD4-c1		9
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		6
tumorous blood cells mbn2		(33)
ovary fGS/OSS		(47)
ovary OSC		(40)
ovary OSS		(42)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		45
Schneider line 2 Sg4		2
embryonic 1182-4H		18
embryonic GM2		14
embryonic Kc167		24
embryonic S1		23
embryonic S3		3
leg disc CME L1		4
wing disc CME-W2		3
wing disc ML-DmD8		10
wing disc ML-DmD9		12
wing disc ML-DmD16-c3		46
wing disc ML-DmD21		22
wing disc ML-DmD32		7
haltere disc ML-DmD17-c3		42
eye-antennal disc ML-DmD11		5
antennal disc ML-DmD20-c5		29
mixed discs ML-DmD4-c1		9
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		6
tumorous blood cells mbn2		33
ovary fGS/OSS		47
ovary OSC		40
ovary OSS		42
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		45
Schneider line 2 Sg4		2
embryonic 1182-4H		18
embryonic GM2		14
embryonic Kc167		24
embryonic S1		23
embryonic S3		3
leg disc CME L1		4
wing disc CME-W2		3
wing disc ML-DmD8		10
wing disc ML-DmD9		12
wing disc ML-DmD16-c3		46
wing disc ML-DmD21		22
wing disc ML-DmD32		7
haltere disc ML-DmD17-c3		42
eye-antennal disc ML-DmD11		5
antennal disc ML-DmD20-c5		29
mixed discs ML-DmD4-c1		9
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		6
tumorous blood cells mbn2		33
ovary fGS/OSS		47
ovary OSC		40
ovary OSS		42
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		43
cold shock, 4-day adult		31
heat shock, 4-day adult		18
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		11
Cadmium 50 mM 48 hrs, 4-day adult		22
Cadmium 100 mM 48 hrs, 4-day adult		39
Copper 0.5 mM 12 hrs, larvae L3		11
Copper 15 mM 48 hrs, 4-day adult		47
Zinc 5 mM 12 hrs, larvae L3		14
Zinc 4.5 mM 48 hrs, 4-day adult		41
Ethanol 2.5% 3 hrs, larvae L3		27
Ethanol 5% 3 hrs, larvae L3		10
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		36
Caffeine 25 mg/ml 48 hrs, 4-day adult		28
Paraquat 5 mM 48 hrs, 4-day adult		31
Paraquat 10 mM 48 hrs, 4-day adult		27
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		(43)
cold shock, 4-day adult		(31)
heat shock, 4-day adult		18
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		11
Cadmium 50 mM 48 hrs, 4-day adult		22
Cadmium 100 mM 48 hrs, 4-day adult		(39)
Copper 0.5 mM 12 hrs, larvae L3		11
Copper 15 mM 48 hrs, 4-day adult		(47)
Zinc 5 mM 12 hrs, larvae L3		14
Zinc 4.5 mM 48 hrs, 4-day adult		(41)
Ethanol 2.5% 3 hrs, larvae L3		(27)
Ethanol 5% 3 hrs, larvae L3		10
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(36)
Caffeine 25 mg/ml 48 hrs, 4-day adult		(28)
Paraquat 5 mM 48 hrs, 4-day adult		(31)
Paraquat 10 mM 48 hrs, 4-day adult		(27)
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		43
cold shock, 4-day adult		31
heat shock, 4-day adult		18
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		11
Cadmium 50 mM 48 hrs, 4-day adult		22
Cadmium 100 mM 48 hrs, 4-day adult		39
Copper 0.5 mM 12 hrs, larvae L3		11
Copper 15 mM 48 hrs, 4-day adult		47
Zinc 5 mM 12 hrs, larvae L3		14
Zinc 4.5 mM 48 hrs, 4-day adult		41
Ethanol 2.5% 3 hrs, larvae L3		27
Ethanol 5% 3 hrs, larvae L3		10
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		36
Caffeine 25 mg/ml 48 hrs, 4-day adult		28
Paraquat 5 mM 48 hrs, 4-day adult		31
Paraquat 10 mM 48 hrs, 4-day adult		27
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		43
cold shock, 4-day adult		31
heat shock, 4-day adult		18
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		11
Cadmium 50 mM 48 hrs, 4-day adult		22
Cadmium 100 mM 48 hrs, 4-day adult		39
Copper 0.5 mM 12 hrs, larvae L3		11
Copper 15 mM 48 hrs, 4-day adult		47
Zinc 5 mM 12 hrs, larvae L3		14
Zinc 4.5 mM 48 hrs, 4-day adult		41
Ethanol 2.5% 3 hrs, larvae L3		27
Ethanol 5% 3 hrs, larvae L3		10
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		36
Caffeine 25 mg/ml 48 hrs, 4-day adult		28
Paraquat 5 mM 48 hrs, 4-day adult		31
Paraquat 10 mM 48 hrs, 4-day adult		27
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		43
cold shock, 4-day adult		31
heat shock, 4-day adult		18
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		11
Cadmium 50 mM 48 hrs, 4-day adult		22
Cadmium 100 mM 48 hrs, 4-day adult		39
Copper 0.5 mM 12 hrs, larvae L3		11
Copper 15 mM 48 hrs, 4-day adult		47
Zinc 5 mM 12 hrs, larvae L3		14
Zinc 4.5 mM 48 hrs, 4-day adult		41
Ethanol 2.5% 3 hrs, larvae L3		27
Ethanol 5% 3 hrs, larvae L3		10
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		36
Caffeine 25 mg/ml 48 hrs, 4-day adult		28
Paraquat 5 mM 48 hrs, 4-day adult		31
Paraquat 10 mM 48 hrs, 4-day adult		27
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		(43)
cold shock, 4-day adult		31
heat shock, 4-day adult		18
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		11
Cadmium 50 mM 48 hrs, 4-day adult		22
Cadmium 100 mM 48 hrs, 4-day adult		(39)
Copper 0.5 mM 12 hrs, larvae L3		11
Copper 15 mM 48 hrs, 4-day adult		(47)
Zinc 5 mM 12 hrs, larvae L3		14
Zinc 4.5 mM 48 hrs, 4-day adult		(41)
Ethanol 2.5% 3 hrs, larvae L3		27
Ethanol 5% 3 hrs, larvae L3		10
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(36)
Caffeine 25 mg/ml 48 hrs, 4-day adult		28
Paraquat 5 mM 48 hrs, 4-day adult		31
Paraquat 10 mM 48 hrs, 4-day adult		27
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		43
cold shock, 4-day adult		31
heat shock, 4-day adult		18
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		11
Cadmium 50 mM 48 hrs, 4-day adult		22
Cadmium 100 mM 48 hrs, 4-day adult		39
Copper 0.5 mM 12 hrs, larvae L3		11
Copper 15 mM 48 hrs, 4-day adult		47
Zinc 5 mM 12 hrs, larvae L3		14
Zinc 4.5 mM 48 hrs, 4-day adult		41
Ethanol 2.5% 3 hrs, larvae L3		27
Ethanol 5% 3 hrs, larvae L3		10
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		36
Caffeine 25 mg/ml 48 hrs, 4-day adult		28
Paraquat 5 mM 48 hrs, 4-day adult		31
Paraquat 10 mM 48 hrs, 4-day adult		27
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		43
cold shock, 4-day adult		31
heat shock, 4-day adult		18
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		11
Cadmium 50 mM 48 hrs, 4-day adult		22
Cadmium 100 mM 48 hrs, 4-day adult		39
Copper 0.5 mM 12 hrs, larvae L3		11
Copper 15 mM 48 hrs, 4-day adult		47
Zinc 5 mM 12 hrs, larvae L3		14
Zinc 4.5 mM 48 hrs, 4-day adult		41
Ethanol 2.5% 3 hrs, larvae L3		27
Ethanol 5% 3 hrs, larvae L3		10
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		36
Caffeine 25 mg/ml 48 hrs, 4-day adult		28
Paraquat 5 mM 48 hrs, 4-day adult		31
Paraquat 10 mM 48 hrs, 4-day adult		27
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0037443

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG1021-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable, with Scer\GAL4^pnr-MD237

CG1021^GD2834

Phenotype manifest in

Allele

Classical Alleles ( 10 )

For All Classical Alleles Show

Allele of CG1021	Mutagen	Stocks	Known lesion
CG1021^A181		1	--
CG1021^c01010	piggyBac transposase	1	--
CG1021^c01120	piggyBac transposase	1	--
CG1021^c06041	piggyBac transposase	1	--
CG1021^c06042	piggyBac transposase	1	--
CG1021^e01970	piggyBac transposase	1	--
CG1021^f07621	piggyBac transposase	1	--
CG1021^NP6590		1	--
CG1021[EY08071]	P-element activity	1	--
CG1021^d11756	P-element activity	0	--

Alleles Carried on Transgenic Constructs ( 2 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG1021	Class	Mutagen	Stocks	Known lesion
CG1021^GD2834		in vitro construct - RNAi in vitro construct - regulatory fusion	2	Yes
CG1021^KK101382		in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD2834}

P{KK101382}

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

PBac{5HPw⁺}CG1021^A181

PBac{PB}CG1021^c01010

PBac{PB}CG1021^c01120

PBac{PB}CG1021^c06041

PBac{PB}CG1021^c06042

PBac{RB}CG1021^e01970

PBac{WH}CG1021^f07621

insertion of enhancer trap binary system

P{GawB}CG1021^NP6590

insertion of mobile activating element

P{EPgy2}CG1021^EY08071

P{XP}CG1021^d11756

Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )

There is no information supporting a biological process, cellular component or molecular function term for this gene.

(Based on a review of available data on: 2010-10-21)

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 0 terms )

Sequence Ontology: Class of Gene

gene_with_edited_transcript

(Graveley et al., 2011)

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG1021 allele

Gene

References

External Data

Linkouts

BioGRID - A database of protein and genetic interactions

•

65993

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0037443

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

40792

Orthologs

OrthoDB Orthologs (58) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG6DFQ7F

Dipteran inclusive ortholog search

EOG6FR118

Insect inclusive ortholog search

EOG69GJC4

Arthropod inclusive ortholog search

EOG6CJSZN

Metazoa inclusive ortholog search

EOG6MH51Z

Orthologs in Drosophila Species (EOG6DFQ7F)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA10158

Drosophila persimilis

Dper\GL22064

Drosophila willistoni

Dwil\GK14490

Drosophila virilis

Dvir\GJ22651

Drosophila mojavensis

Dmoj\GI24584

Drosophila grimshawi

Dgri\GH18085

Orthologs in non-Drosophila Dipterans (EOG6FR118)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL008067

Anopheles gambiae

Malaria mosquito

Agam\AGAP004508

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ009137

Orthologs in non-Dipteran Insects (EOG69GJC4)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\GB50390

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG010874

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH12205

Atta cephalotes

Leafcutter ant

Acep\ACEP18011

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO21969

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL15196

Linepithema humile

Argentine ant

Lhum\LH24774

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB24386

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB24387

Solenopsis invicta

Red fire ant

Sinv\SINV18582

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI000320

Bombyx mori

Silkmoth

Bmor\BGIBMGA004539

Pediculus humanus

Human body louse

Phum\PHUM125760

Tribolium castaneum

Red flour beetle

Tcas\TC003548

Orthologs in non-Insect Arthropods (EOG6CJSZN)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Daphnia pulex

Water flea

Dpux\CELA2A

Ixodes scapularis

Deer tick

Isca\ISCW020304

Orthologs in non-Arthropod Metazoa (EOG6MH51Z)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Caenorhabditis elegans

Nematode

Cele\C15H9.4

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_004228gn

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_025081gn

Danio rerio

Zebrafish

Drer\ENSDARG00000076747

Danio rerio

Zebrafish

Drer\tmcc3

Danio rerio

Zebrafish

Drer\LOC560064

Danio rerio

Zebrafish

Drer\zgc:153972

Xenopus tropicalis

Western clawed frog

Xtro\tmcc3

Xenopus tropicalis

Western clawed frog

Xtro\tmcc1

Xenopus tropicalis

Western clawed frog

Xtro\tmcc2

Gallus gallus

Domestic chicken

Ggal\TMCC1

Gallus gallus

Domestic chicken

Ggal\TMCC3

Gallus gallus

Domestic chicken

Ggal\TMCC2

Mus musculus

House mouse

Mmus\Tmcc3

Mus musculus

House mouse

Mmus\Tmcc2

Mus musculus

House mouse

Mmus\Tex28

Mus musculus

House mouse

Mmus\Tmcc1

Rattus norvegicus

Norway rat

Rnor\Tex28

Rattus norvegicus

Norway rat

Rnor\Tmcc1

Rattus norvegicus

Norway rat

Rnor\Tmcc3

Rattus norvegicus

Norway rat

Rnor\Tmcc2

Homo sapiens

Human

Hsap\ENSG00000102080

Homo sapiens

Human

Hsap\TMCC1

Homo sapiens

Human

Hsap\ENSG00000185254

Homo sapiens

Human

Hsap\ENSG00000182242

Homo sapiens

Human

Hsap\TMCC2

Homo sapiens

Human

Hsap\TMCC3

Human Orthologs (6)

Gene

OMIM

HGNC

AAA Orthologs (11) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA10158

Drosophila persimilis

Dper\GL22064

Drosophila willistoni

Dwil\GK14490

Drosophila virilis

Dvir\GJ22651

Drosophila mojavensis

Dmoj\GI24584

Drosophila grimshawi

Dgri\GH18085

Stocks & Reagents

Stocks Listed in FlyBase ( 11 )

Bloomington

22314

y¹ w^67c23; P{EPgy2}CG1021^EY08071

16060

y¹ w¹¹¹⁸; PBac{5HPw⁺}CG1021^A181/TM3, Sb¹ Ser¹

Harvard

PBac{PB}CG1021^c01010

PBac{PB}CG1021^c01120

PBac{PB}CG1021^c06041

PBac{PB}CG1021^c06042

PBac{RB}CG1021^e01970

PBac{WH}CG1021^f07621

Kyoto

105275

y^* w^*; P{GawB}CG1021^NP6590 / TM6, P{UAS-lacZ.UW23-1}UW23-1

VDRC

v37336

w¹¹¹⁸; P{GD2834}v37336

v37338

w¹¹¹⁸; P{GD2834}v37338/TM3

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 64 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0037443

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

40792

Antibody Information

polyclonal

(Hopkins, 2013)

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Source for merge of: CG1021 anon-WO0118547.375

(FlyBase, 1996-)

Additional comments

Source for merge of CG1021 anon-WO0118547.375 was sequence comparison (date:051113).

(FlyBase, 1996-)

Other Comments

Area matching Drosophila EST AA390453.

(Davies, 2001.3.15)

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

RefSeq (Proteins)

•

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

40792

UniProtKB/TrEMBL

•

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Predicted transmembrane/coiled-coil 2 protein (IPR019394)

Linkouts

BioGRID - A database of protein and genetic interactions

•

65993

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0037443

DRSC - Results from RNAi screens.

•

FBgn0037443

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0037443

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG1021-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0037443

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

40792

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

40792

modMine - Data generated by the modENCODE project.

•

FBgn0037443

Synonyms & Secondary IDs ( 2 )

Reported As

Symbol Synonym

anon-WO0118547.375

CG1021

(Keleman et al., 2009.8.5)

Name Synonym

Secondary FlyBase IDs

FBgn0062058

References ( 21 )

Generate a list of

All references relating to this gene ( 21 )

List References by type

Recent research papers ( 1 )

Hopkins, 2013, PLoS ONE 8(2): e55810: Neurodegeneration in a Drosophila Model for the Function of TMCC2, an Amyloid Protein Precursor-Interacting and Apolipoprotein E-Binding Protein. [FBrf0220834]

Show all research papers ...