MP2, PAE1, Melanization Protease 2
Please see the GBrowse view of Dmel\Sp7 or the JBrowse view of Dmel\Sp7 for information on other features
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Gene model reviewed during 5.49
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 6.03
Interacts with Spn27A.
The clip domain consists of 35-55 residues which are 'knitted' together usually by 3 conserved disulfide bonds forming a clip-like compact structure.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Sp7 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Sp7 in GBrowse 23-48
3-48
3-44.4
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Sp7 CG3066
Source for identity of: Sp7 MP2
Source for merge of: CG3066 anon-Ryu
RNAi of Sp7 reduces melanization at the wound site of infections, indicating that it is involved in the prophenoloxidase cascade.
