General Information Symbol Dmel\ CG2943Species D. melanogaster Name Annotation symbol CG2943 Feature type protein_coding_gene FlyBase ID FBgn0037530 Gene Model Status Current Stock availability 4 publicly
available Genomic Location Chromosome (arm) 3R Recombination map Cytogenetic map 84E4-84E5 Sequence location 3R:3,728,752..3,733,085 [-]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information This gene is referred to in FlyBase by the symbol
Dmel\CG2943 (FBgn0037530). It is a protein_coding_gene from
Drosophila melanogaster . Its
molecular function is unknown. The
biological processes in which it is involved are not known.
5 alleles are reported . No phenotypic data is available. It has
4 annotated transcripts and
4 annotated polypeptides .
Protein features are: Domain of unknown function DUF1620; ER membrane protein complex subunit 1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult crop, adult fat body, adult testis, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1627142_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG2943. Gene sequence location is
3R:3728752..3733085 .
User Contributed Data
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FB2013_03
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.49
DGC clone appears problematic (LD30573): incomplete CDS.
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript Expression
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
250.575
Larval Midgut
246.4
Larval Hindgut
333.7
Larval Malpighian Tubules
366.2
Larval Fat Body
331.6
Larval Salivary Gland
384.2
Larval Trachea
271.75
Larval Carcass
332.475
Adult Head
247.5
Adult Eye
228.15
Adult Brain
260
Adult Thoracic-Abdominal Ganglion
285.4
Adult Crop
506.1
Adult Midgut
273.8
Adult Hindgut
375.8
Adult Malpighian Tubules
247.5
Adult Fat Body
619.7
Adult Salivary Gland
440.6
Adult Heart
426
Adult VirginFemale Spermatheca
366.8
Adult InseminatedFemale Spermatheca
398.4
Adult Ovary
324.7
Adult Testis
542.4
Adult Male Accessory Gland
479.8
Adult Carcass
545.8
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
250.575
Larval Midgut
246.4
Larval Hindgut
333.7
Larval Malpighian Tubules
366.2
Larval Fat Body
331.6
Larval Salivary Gland
384.2
Larval Trachea
271.75
Larval Carcass
332.475
Adult Head
247.5
Adult Eye
228.15
Adult Brain
260
Adult Thoracic-Abdominal Ganglion
285.4
Adult Crop
506.1
Adult Midgut
273.8
Adult Hindgut
375.8
Adult Malpighian Tubules
247.5
Adult Fat Body
(619.7)
Adult Salivary Gland
440.6
Adult Heart
426
Adult VirginFemale Spermatheca
366.8
Adult InseminatedFemale Spermatheca
398.4
Adult Ovary
324.7
Adult Testis
(542.4)
Adult Male Accessory Gland
479.8
Adult Carcass
(545.8)
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
250.575
Larval Midgut
246.4
Larval Hindgut
333.7
Larval Malpighian Tubules
366.2
Larval Fat Body
331.6
Larval Salivary Gland
384.2
Larval Trachea
271.75
Larval Carcass
332.475
Adult Head
247.5
Adult Eye
228.15
Adult Brain
260
Adult Thoracic-Abdominal Ganglion
285.4
Adult Crop
506.1
Adult Midgut
273.8
Adult Hindgut
375.8
Adult Malpighian Tubules
247.5
Adult Fat Body
619.7
Adult Salivary Gland
440.6
Adult Heart
426
Adult VirginFemale Spermatheca
366.8
Adult InseminatedFemale Spermatheca
398.4
Adult Ovary
324.7
Adult Testis
542.4
Adult Male Accessory Gland
479.8
Adult Carcass
545.8
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
250.575
Larval Midgut
246.4
Larval Hindgut
333.7
Larval Malpighian Tubules
366.2
Larval Fat Body
331.6
Larval Salivary Gland
384.2
Larval Trachea
271.75
Larval Carcass
332.475
Adult Head
247.5
Adult Eye
228.15
Adult Brain
260
Adult Thoracic-Abdominal Ganglion
285.4
Adult Crop
506.1
Adult Midgut
273.8
Adult Hindgut
375.8
Adult Malpighian Tubules
247.5
Adult Fat Body
619.7
Adult Salivary Gland
440.6
Adult Heart
426
Adult VirginFemale Spermatheca
366.8
Adult InseminatedFemale Spermatheca
398.4
Adult Ovary
324.7
Adult Testis
542.4
Adult Male Accessory Gland
479.8
Adult Carcass
545.8
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
250.575
Larval Midgut
246.4
Larval Hindgut
333.7
Larval Malpighian Tubules
366.2
Larval Fat Body
331.6
Larval Salivary Gland
384.2
Larval Trachea
271.75
Larval Carcass
332.475
Adult Head
247.5
Adult Eye
228.15
Adult Brain
260
Adult Thoracic-Abdominal Ganglion
285.4
Adult Crop
506.1
Adult Midgut
273.8
Adult Hindgut
375.8
Adult Malpighian Tubules
247.5
Adult Fat Body
619.7
Adult Salivary Gland
440.6
Adult Heart
426
Adult VirginFemale Spermatheca
366.8
Adult InseminatedFemale Spermatheca
398.4
Adult Ovary
324.7
Adult Testis
542.4
Adult Male Accessory Gland
479.8
Adult Carcass
545.8
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
250.575
Larval Midgut
246.4
Larval Hindgut
333.7
Larval Malpighian Tubules
366.2
Larval Fat Body
331.6
Larval Salivary Gland
384.2
Larval Trachea
271.75
Larval Carcass
332.475
Adult Head
247.5
Adult Eye
228.15
Adult Brain
260
Adult Thoracic-Abdominal Ganglion
285.4
Adult Crop
506.1
Adult Midgut
273.8
Adult Hindgut
375.8
Adult Malpighian Tubules
247.5
Adult Fat Body
619.7
Adult Salivary Gland
440.6
Adult Heart
426
Adult VirginFemale Spermatheca
366.8
Adult InseminatedFemale Spermatheca
398.4
Adult Ovary
324.7
Adult Testis
542.4
Adult Male Accessory Gland
479.8
Adult Carcass
545.8
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
250.575
Larval Midgut
246.4
Larval Hindgut
333.7
Larval Malpighian Tubules
366.2
Larval Fat Body
331.6
Larval Salivary Gland
384.2
Larval Trachea
271.75
Larval Carcass
332.475
Adult Head
247.5
Adult Eye
228.15
Adult Brain
260
Adult Thoracic-Abdominal Ganglion
285.4
Adult Crop
506.1
Adult Midgut
273.8
Adult Hindgut
375.8
Adult Malpighian Tubules
247.5
Adult Fat Body
619.7
Adult Salivary Gland
440.6
Adult Heart
426
Adult VirginFemale Spermatheca
366.8
Adult InseminatedFemale Spermatheca
398.4
Adult Ovary
324.7
Adult Testis
542.4
Adult Male Accessory Gland
479.8
Adult Carcass
545.8
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
250.575
Larval Midgut
246.4
Larval Hindgut
333.7
Larval Malpighian Tubules
366.2
Larval Fat Body
331.6
Larval Salivary Gland
384.2
Larval Trachea
271.75
Larval Carcass
332.475
Adult Head
247.5
Adult Eye
228.15
Adult Brain
260
Adult Thoracic-Abdominal Ganglion
285.4
Adult Crop
506.1
Adult Midgut
273.8
Adult Hindgut
375.8
Adult Malpighian Tubules
247.5
Adult Fat Body
619.7
Adult Salivary Gland
440.6
Adult Heart
426
Adult VirginFemale Spermatheca
366.8
Adult InseminatedFemale Spermatheca
398.4
Adult Ovary
324.7
Adult Testis
542.4
Adult Male Accessory Gland
479.8
Adult Carcass
545.8
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
247.5
NA
Eye
228.15
NA
Brain
260
250.575
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
285.4
NA
Crop
506.1
246.4
Midgut
273.8
333.7
Hindgut
375.8
366.2
Malpighian Tubules
247.5
331.6
Fat Body
619.7
384.2
Salivary Gland
440.6
NA
Heart
426
271.75
Trachea
NA
NA
VirginFemale Spermatheca
366.8
NA
InseminatedFemale Spermatheca
398.4
NA
Ovary
324.7
NA
Testis
542.4
NA
Male Accessory Gland
479.8
332.475
Carcass
545.8
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
35
central nervous system, larvae L3
21
central nervous system, pupae P8
26
head, virgin 1-day female
14
head, virgin 4-day female
12
head, virgin 20-day female
16
head, mated 1-day female
11
head, mated 4-day female
13
head, mated 20-day female
14
head, mated 1-day male
15
head, mated 4-day male
20
head, mated 20-day male
24
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
4
digestive system, larvae L3 wandering
16
digestive system, 1-day adult
13
digestive system, 4-day adult
17
digestive system, 20-day adult
16
fat body, larvae L3 wandering
6
fat body, white prepupae
13
fat body, pupae P8
14
carcass, larvae L3 wandering
21
carcass, 1-day adult
15
carcass, 4-day adult
21
carcass, 20-day adult
19
ovary, virgin 4-day female
43
ovary, mated 4-day female
35
testis, mated 4-day male
54
accessory gland, mated 4-day male
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(35)
central nervous system, larvae L3
21
central nervous system, pupae P8
26
head, virgin 1-day female
14
head, virgin 4-day female
12
head, virgin 20-day female
16
head, mated 1-day female
11
head, mated 4-day female
13
head, mated 20-day female
14
head, mated 1-day male
15
head, mated 4-day male
20
head, mated 20-day male
24
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
4
digestive system, larvae L3 wandering
16
digestive system, 1-day adult
13
digestive system, 4-day adult
17
digestive system, 20-day adult
16
fat body, larvae L3 wandering
6
fat body, white prepupae
13
fat body, pupae P8
14
carcass, larvae L3 wandering
21
carcass, 1-day adult
15
carcass, 4-day adult
21
carcass, 20-day adult
19
ovary, virgin 4-day female
(43)
ovary, mated 4-day female
(35)
testis, mated 4-day male
(54)
accessory gland, mated 4-day male
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
35
central nervous system, larvae L3
21
central nervous system, pupae P8
26
head, virgin 1-day female
14
head, virgin 4-day female
12
head, virgin 20-day female
16
head, mated 1-day female
11
head, mated 4-day female
13
head, mated 20-day female
14
head, mated 1-day male
15
head, mated 4-day male
20
head, mated 20-day male
24
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
4
digestive system, larvae L3 wandering
16
digestive system, 1-day adult
13
digestive system, 4-day adult
17
digestive system, 20-day adult
16
fat body, larvae L3 wandering
6
fat body, white prepupae
13
fat body, pupae P8
14
carcass, larvae L3 wandering
21
carcass, 1-day adult
15
carcass, 4-day adult
21
carcass, 20-day adult
19
ovary, virgin 4-day female
43
ovary, mated 4-day female
35
testis, mated 4-day male
54
accessory gland, mated 4-day male
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
35
central nervous system, larvae L3
21
central nervous system, pupae P8
26
head, virgin 1-day female
14
head, virgin 4-day female
12
head, virgin 20-day female
16
head, mated 1-day female
11
head, mated 4-day female
13
head, mated 20-day female
14
head, mated 1-day male
15
head, mated 4-day male
20
head, mated 20-day male
24
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
4
digestive system, larvae L3 wandering
16
digestive system, 1-day adult
13
digestive system, 4-day adult
17
digestive system, 20-day adult
16
fat body, larvae L3 wandering
6
fat body, white prepupae
13
fat body, pupae P8
14
carcass, larvae L3 wandering
21
carcass, 1-day adult
15
carcass, 4-day adult
21
carcass, 20-day adult
19
ovary, virgin 4-day female
43
ovary, mated 4-day female
35
testis, mated 4-day male
54
accessory gland, mated 4-day male
16
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
35
central nervous system, larvae L3
21
central nervous system, pupae P8
26
head, virgin 1-day female
14
head, virgin 4-day female
12
head, virgin 20-day female
16
head, mated 1-day female
11
head, mated 4-day female
13
head, mated 20-day female
14
head, mated 1-day male
15
head, mated 4-day male
20
head, mated 20-day male
24
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
4
digestive system, larvae L3 wandering
16
digestive system, 1-day adult
13
digestive system, 4-day adult
17
digestive system, 20-day adult
16
fat body, larvae L3 wandering
6
fat body, white prepupae
13
fat body, pupae P8
14
carcass, larvae L3 wandering
21
carcass, 1-day adult
15
carcass, 4-day adult
21
carcass, 20-day adult
19
ovary, virgin 4-day female
43
ovary, mated 4-day female
35
testis, mated 4-day male
54
accessory gland, mated 4-day male
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(35)
central nervous system, larvae L3
21
central nervous system, pupae P8
26
head, virgin 1-day female
14
head, virgin 4-day female
12
head, virgin 20-day female
16
head, mated 1-day female
11
head, mated 4-day female
13
head, mated 20-day female
14
head, mated 1-day male
15
head, mated 4-day male
20
head, mated 20-day male
24
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
4
digestive system, larvae L3 wandering
16
digestive system, 1-day adult
13
digestive system, 4-day adult
17
digestive system, 20-day adult
16
fat body, larvae L3 wandering
6
fat body, white prepupae
13
fat body, pupae P8
14
carcass, larvae L3 wandering
21
carcass, 1-day adult
15
carcass, 4-day adult
21
carcass, 20-day adult
19
ovary, virgin 4-day female
(43)
ovary, mated 4-day female
(35)
testis, mated 4-day male
(54)
accessory gland, mated 4-day male
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
35
central nervous system, larvae L3
21
central nervous system, pupae P8
26
head, virgin 1-day female
14
head, virgin 4-day female
12
head, virgin 20-day female
16
head, mated 1-day female
11
head, mated 4-day female
13
head, mated 20-day female
14
head, mated 1-day male
15
head, mated 4-day male
20
head, mated 20-day male
24
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
4
digestive system, larvae L3 wandering
16
digestive system, 1-day adult
13
digestive system, 4-day adult
17
digestive system, 20-day adult
16
fat body, larvae L3 wandering
6
fat body, white prepupae
13
fat body, pupae P8
14
carcass, larvae L3 wandering
21
carcass, 1-day adult
15
carcass, 4-day adult
21
carcass, 20-day adult
19
ovary, virgin 4-day female
43
ovary, mated 4-day female
35
testis, mated 4-day male
54
accessory gland, mated 4-day male
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
35
central nervous system, larvae L3
21
central nervous system, pupae P8
26
head, virgin 1-day female
14
head, virgin 4-day female
12
head, virgin 20-day female
16
head, mated 1-day female
11
head, mated 4-day female
13
head, mated 20-day female
14
head, mated 1-day male
15
head, mated 4-day male
20
head, mated 20-day male
24
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
4
digestive system, larvae L3 wandering
16
digestive system, 1-day adult
13
digestive system, 4-day adult
17
digestive system, 20-day adult
16
fat body, larvae L3 wandering
6
fat body, white prepupae
13
fat body, pupae P8
14
carcass, larvae L3 wandering
21
carcass, 1-day adult
15
carcass, 4-day adult
21
carcass, 20-day adult
19
ovary, virgin 4-day female
43
ovary, mated 4-day female
35
testis, mated 4-day male
54
accessory gland, mated 4-day male
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
95
embryo 02-04hr
115
embryo 04-06hr
71
embryo 06-08hr
76
embryo 08-10hr
85
embryo 10-12hr
79
embryo 12-14hr
62
embryo 14-16hr
69
embryo 16-18hr
55
embryo 18-20hr
39
embryo 20-22hr
32
embryo 22-24hr
31
larva L1
42
larva L2
62
larva L3 12hr old
43
larva L3 puffstage 1-2
26
larva L3 puffstage 3-6
40
larva L3 puffstage 7-9
47
white prepupae new
51
white prepupae 12hr
39
white prepupae 24hr
51
pupae 2d postWPP
51
pupae 3d postWPP
48
pupae 4d postWPP
35
adult male 01day
55
adult male 05day
74
adult male 30day
63
adult female 01day
54
adult female 05day
71
adult female 30day
70
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(95)
embryo 02-04hr
(115)
embryo 04-06hr
(71)
embryo 06-08hr
(76)
embryo 08-10hr
(85)
embryo 10-12hr
(79)
embryo 12-14hr
(62)
embryo 14-16hr
(69)
embryo 16-18hr
(55)
embryo 18-20hr
(39)
embryo 20-22hr
(32)
embryo 22-24hr
(31)
larva L1
(42)
larva L2
(62)
larva L3 12hr old
(43)
larva L3 puffstage 1-2
26
larva L3 puffstage 3-6
(40)
larva L3 puffstage 7-9
(47)
white prepupae new
(51)
white prepupae 12hr
(39)
white prepupae 24hr
(51)
pupae 2d postWPP
(51)
pupae 3d postWPP
(48)
pupae 4d postWPP
(35)
adult male 01day
(55)
adult male 05day
(74)
adult male 30day
(63)
adult female 01day
(54)
adult female 05day
(71)
adult female 30day
(70)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
95
embryo 02-04hr
(115)
embryo 04-06hr
71
embryo 06-08hr
76
embryo 08-10hr
85
embryo 10-12hr
79
embryo 12-14hr
62
embryo 14-16hr
69
embryo 16-18hr
55
embryo 18-20hr
39
embryo 20-22hr
32
embryo 22-24hr
31
larva L1
42
larva L2
62
larva L3 12hr old
43
larva L3 puffstage 1-2
26
larva L3 puffstage 3-6
40
larva L3 puffstage 7-9
47
white prepupae new
51
white prepupae 12hr
39
white prepupae 24hr
51
pupae 2d postWPP
51
pupae 3d postWPP
48
pupae 4d postWPP
35
adult male 01day
55
adult male 05day
74
adult male 30day
63
adult female 01day
54
adult female 05day
71
adult female 30day
70
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
95
embryo 02-04hr
115
embryo 04-06hr
71
embryo 06-08hr
76
embryo 08-10hr
85
embryo 10-12hr
79
embryo 12-14hr
62
embryo 14-16hr
69
embryo 16-18hr
55
embryo 18-20hr
39
embryo 20-22hr
32
embryo 22-24hr
31
larva L1
42
larva L2
62
larva L3 12hr old
43
larva L3 puffstage 1-2
26
larva L3 puffstage 3-6
40
larva L3 puffstage 7-9
47
white prepupae new
51
white prepupae 12hr
39
white prepupae 24hr
51
pupae 2d postWPP
51
pupae 3d postWPP
48
pupae 4d postWPP
35
adult male 01day
55
adult male 05day
74
adult male 30day
63
adult female 01day
54
adult female 05day
71
adult female 30day
70
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
95
embryo 02-04hr
115
embryo 04-06hr
71
embryo 06-08hr
76
embryo 08-10hr
85
embryo 10-12hr
79
embryo 12-14hr
62
embryo 14-16hr
69
embryo 16-18hr
55
embryo 18-20hr
39
embryo 20-22hr
32
embryo 22-24hr
31
larva L1
42
larva L2
62
larva L3 12hr old
43
larva L3 puffstage 1-2
26
larva L3 puffstage 3-6
40
larva L3 puffstage 7-9
47
white prepupae new
51
white prepupae 12hr
39
white prepupae 24hr
51
pupae 2d postWPP
51
pupae 3d postWPP
48
pupae 4d postWPP
35
adult male 01day
55
adult male 05day
74
adult male 30day
63
adult female 01day
54
adult female 05day
71
adult female 30day
70
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(95)
embryo 02-04hr
(115)
embryo 04-06hr
(71)
embryo 06-08hr
(76)
embryo 08-10hr
(85)
embryo 10-12hr
(79)
embryo 12-14hr
(62)
embryo 14-16hr
(69)
embryo 16-18hr
(55)
embryo 18-20hr
(39)
embryo 20-22hr
32
embryo 22-24hr
31
larva L1
(42)
larva L2
(62)
larva L3 12hr old
(43)
larva L3 puffstage 1-2
26
larva L3 puffstage 3-6
(40)
larva L3 puffstage 7-9
(47)
white prepupae new
(51)
white prepupae 12hr
(39)
white prepupae 24hr
(51)
pupae 2d postWPP
(51)
pupae 3d postWPP
(48)
pupae 4d postWPP
(35)
adult male 01day
(55)
adult male 05day
(74)
adult male 30day
(63)
adult female 01day
(54)
adult female 05day
(71)
adult female 30day
(70)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
95
embryo 02-04hr
115
embryo 04-06hr
71
embryo 06-08hr
76
embryo 08-10hr
85
embryo 10-12hr
79
embryo 12-14hr
62
embryo 14-16hr
69
embryo 16-18hr
55
embryo 18-20hr
39
embryo 20-22hr
32
embryo 22-24hr
31
larva L1
42
larva L2
62
larva L3 12hr old
43
larva L3 puffstage 1-2
26
larva L3 puffstage 3-6
40
larva L3 puffstage 7-9
47
white prepupae new
51
white prepupae 12hr
39
white prepupae 24hr
51
pupae 2d postWPP
51
pupae 3d postWPP
48
pupae 4d postWPP
35
adult male 01day
55
adult male 05day
74
adult male 30day
63
adult female 01day
54
adult female 05day
71
adult female 30day
70
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
95
embryo 02-04hr
115
embryo 04-06hr
71
embryo 06-08hr
76
embryo 08-10hr
85
embryo 10-12hr
79
embryo 12-14hr
62
embryo 14-16hr
69
embryo 16-18hr
55
embryo 18-20hr
39
embryo 20-22hr
32
embryo 22-24hr
31
larva L1
42
larva L2
62
larva L3 12hr old
43
larva L3 puffstage 1-2
26
larva L3 puffstage 3-6
40
larva L3 puffstage 7-9
47
white prepupae new
51
white prepupae 12hr
39
white prepupae 24hr
51
pupae 2d postWPP
51
pupae 3d postWPP
48
pupae 4d postWPP
35
adult male 01day
55
adult male 05day
74
adult male 30day
63
adult female 01day
54
adult female 05day
71
adult female 30day
70
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
65
Schneider line 2 Sg4
79
embryonic 1182-4H
42
embryonic GM2
86
embryonic Kc167
33
embryonic S1
46
embryonic S3
78
leg disc CME L1
50
wing disc CME-W2
70
wing disc ML-DmD8
35
wing disc ML-DmD9
26
wing disc ML-DmD16-c3
27
wing disc ML-DmD21
22
wing disc ML-DmD32
37
haltere disc ML-DmD17-c3
58
eye-antennal disc ML-DmD11
50
antennal disc ML-DmD20-c5
41
mixed discs ML-DmD4-c1
37
CNS ML-DmBG1-c1
37
CNS ML-DmBG2-c2
56
tumorous blood cells mbn2
79
ovary fGS/OSS
16
ovary OSC
19
ovary OSS
9
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(65)
Schneider line 2 Sg4
(79)
embryonic 1182-4H
(42)
embryonic GM2
(86)
embryonic Kc167
(33)
embryonic S1
(46)
embryonic S3
(78)
leg disc CME L1
(50)
wing disc CME-W2
(70)
wing disc ML-DmD8
(35)
wing disc ML-DmD9
26
wing disc ML-DmD16-c3
(27)
wing disc ML-DmD21
22
wing disc ML-DmD32
(37)
haltere disc ML-DmD17-c3
(58)
eye-antennal disc ML-DmD11
(50)
antennal disc ML-DmD20-c5
(41)
mixed discs ML-DmD4-c1
(37)
CNS ML-DmBG1-c1
(37)
CNS ML-DmBG2-c2
(56)
tumorous blood cells mbn2
(79)
ovary fGS/OSS
16
ovary OSC
19
ovary OSS
9
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
65
Schneider line 2 Sg4
79
embryonic 1182-4H
42
embryonic GM2
86
embryonic Kc167
33
embryonic S1
46
embryonic S3
78
leg disc CME L1
50
wing disc CME-W2
70
wing disc ML-DmD8
35
wing disc ML-DmD9
26
wing disc ML-DmD16-c3
27
wing disc ML-DmD21
22
wing disc ML-DmD32
37
haltere disc ML-DmD17-c3
58
eye-antennal disc ML-DmD11
50
antennal disc ML-DmD20-c5
41
mixed discs ML-DmD4-c1
37
CNS ML-DmBG1-c1
37
CNS ML-DmBG2-c2
56
tumorous blood cells mbn2
79
ovary fGS/OSS
16
ovary OSC
19
ovary OSS
9
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
65
Schneider line 2 Sg4
79
embryonic 1182-4H
42
embryonic GM2
86
embryonic Kc167
33
embryonic S1
46
embryonic S3
78
leg disc CME L1
50
wing disc CME-W2
70
wing disc ML-DmD8
35
wing disc ML-DmD9
26
wing disc ML-DmD16-c3
27
wing disc ML-DmD21
22
wing disc ML-DmD32
37
haltere disc ML-DmD17-c3
58
eye-antennal disc ML-DmD11
50
antennal disc ML-DmD20-c5
41
mixed discs ML-DmD4-c1
37
CNS ML-DmBG1-c1
37
CNS ML-DmBG2-c2
56
tumorous blood cells mbn2
79
ovary fGS/OSS
16
ovary OSC
19
ovary OSS
9
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
65
Schneider line 2 Sg4
79
embryonic 1182-4H
42
embryonic GM2
86
embryonic Kc167
33
embryonic S1
46
embryonic S3
78
leg disc CME L1
50
wing disc CME-W2
70
wing disc ML-DmD8
35
wing disc ML-DmD9
26
wing disc ML-DmD16-c3
27
wing disc ML-DmD21
22
wing disc ML-DmD32
37
haltere disc ML-DmD17-c3
58
eye-antennal disc ML-DmD11
50
antennal disc ML-DmD20-c5
41
mixed discs ML-DmD4-c1
37
CNS ML-DmBG1-c1
37
CNS ML-DmBG2-c2
56
tumorous blood cells mbn2
79
ovary fGS/OSS
16
ovary OSC
19
ovary OSS
9
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(65)
Schneider line 2 Sg4
(79)
embryonic 1182-4H
(42)
embryonic GM2
(86)
embryonic Kc167
(33)
embryonic S1
(46)
embryonic S3
(78)
leg disc CME L1
(50)
wing disc CME-W2
(70)
wing disc ML-DmD8
(35)
wing disc ML-DmD9
26
wing disc ML-DmD16-c3
27
wing disc ML-DmD21
22
wing disc ML-DmD32
(37)
haltere disc ML-DmD17-c3
(58)
eye-antennal disc ML-DmD11
(50)
antennal disc ML-DmD20-c5
(41)
mixed discs ML-DmD4-c1
(37)
CNS ML-DmBG1-c1
(37)
CNS ML-DmBG2-c2
(56)
tumorous blood cells mbn2
(79)
ovary fGS/OSS
16
ovary OSC
19
ovary OSS
9
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
65
Schneider line 2 Sg4
79
embryonic 1182-4H
42
embryonic GM2
86
embryonic Kc167
33
embryonic S1
46
embryonic S3
78
leg disc CME L1
50
wing disc CME-W2
70
wing disc ML-DmD8
35
wing disc ML-DmD9
26
wing disc ML-DmD16-c3
27
wing disc ML-DmD21
22
wing disc ML-DmD32
37
haltere disc ML-DmD17-c3
58
eye-antennal disc ML-DmD11
50
antennal disc ML-DmD20-c5
41
mixed discs ML-DmD4-c1
37
CNS ML-DmBG1-c1
37
CNS ML-DmBG2-c2
56
tumorous blood cells mbn2
79
ovary fGS/OSS
16
ovary OSC
19
ovary OSS
9
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
65
Schneider line 2 Sg4
79
embryonic 1182-4H
42
embryonic GM2
86
embryonic Kc167
33
embryonic S1
46
embryonic S3
78
leg disc CME L1
50
wing disc CME-W2
70
wing disc ML-DmD8
35
wing disc ML-DmD9
26
wing disc ML-DmD16-c3
27
wing disc ML-DmD21
22
wing disc ML-DmD32
37
haltere disc ML-DmD17-c3
58
eye-antennal disc ML-DmD11
50
antennal disc ML-DmD20-c5
41
mixed discs ML-DmD4-c1
37
CNS ML-DmBG1-c1
37
CNS ML-DmBG2-c2
56
tumorous blood cells mbn2
79
ovary fGS/OSS
16
ovary OSC
19
ovary OSS
9
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
9
cold shock, 4-day adult
7
heat shock, 4-day adult
25
Cadmium 50 mM 6 hrs, larvae L3
18
Cadmium 50 mM 12 hrs, larvae L3
15
Cadmium 50 mM 48 hrs, 4-day adult
21
Cadmium 100 mM 48 hrs, 4-day adult
29
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
23
Zinc 5 mM 12 hrs, larvae L3
6
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
37
Ethanol 5% 3 hrs, larvae L3
19
Ethanol 10% 3 hrs, larvae L3
16
Caffeine 1.5 mg/ml 4 hrs, larvae L3
16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
28
Caffeine 25 mg/ml 48 hrs, 4-day adult
10
Paraquat 5 mM 48 hrs, 4-day adult
31
Paraquat 10 mM 48 hrs, 4-day adult
37
Rotenone 2 μg 12 hrs, larvae L3
21
Rotenone 8 μg 12 hrs, larvae L3
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
9
cold shock, 4-day adult
7
heat shock, 4-day adult
25
Cadmium 50 mM 6 hrs, larvae L3
18
Cadmium 50 mM 12 hrs, larvae L3
15
Cadmium 50 mM 48 hrs, 4-day adult
21
Cadmium 100 mM 48 hrs, 4-day adult
(29)
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
23
Zinc 5 mM 12 hrs, larvae L3
6
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
(37)
Ethanol 5% 3 hrs, larvae L3
19
Ethanol 10% 3 hrs, larvae L3
16
Caffeine 1.5 mg/ml 4 hrs, larvae L3
16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(28)
Caffeine 25 mg/ml 48 hrs, 4-day adult
10
Paraquat 5 mM 48 hrs, 4-day adult
(31)
Paraquat 10 mM 48 hrs, 4-day adult
(37)
Rotenone 2 μg 12 hrs, larvae L3
21
Rotenone 8 μg 12 hrs, larvae L3
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
9
cold shock, 4-day adult
7
heat shock, 4-day adult
25
Cadmium 50 mM 6 hrs, larvae L3
18
Cadmium 50 mM 12 hrs, larvae L3
15
Cadmium 50 mM 48 hrs, 4-day adult
21
Cadmium 100 mM 48 hrs, 4-day adult
29
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
23
Zinc 5 mM 12 hrs, larvae L3
6
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
37
Ethanol 5% 3 hrs, larvae L3
19
Ethanol 10% 3 hrs, larvae L3
16
Caffeine 1.5 mg/ml 4 hrs, larvae L3
16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
28
Caffeine 25 mg/ml 48 hrs, 4-day adult
10
Paraquat 5 mM 48 hrs, 4-day adult
31
Paraquat 10 mM 48 hrs, 4-day adult
37
Rotenone 2 μg 12 hrs, larvae L3
21
Rotenone 8 μg 12 hrs, larvae L3
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
9
cold shock, 4-day adult
7
heat shock, 4-day adult
25
Cadmium 50 mM 6 hrs, larvae L3
18
Cadmium 50 mM 12 hrs, larvae L3
15
Cadmium 50 mM 48 hrs, 4-day adult
21
Cadmium 100 mM 48 hrs, 4-day adult
29
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
23
Zinc 5 mM 12 hrs, larvae L3
6
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
37
Ethanol 5% 3 hrs, larvae L3
19
Ethanol 10% 3 hrs, larvae L3
16
Caffeine 1.5 mg/ml 4 hrs, larvae L3
16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
28
Caffeine 25 mg/ml 48 hrs, 4-day adult
10
Paraquat 5 mM 48 hrs, 4-day adult
31
Paraquat 10 mM 48 hrs, 4-day adult
37
Rotenone 2 μg 12 hrs, larvae L3
21
Rotenone 8 μg 12 hrs, larvae L3
16
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
9
cold shock, 4-day adult
7
heat shock, 4-day adult
25
Cadmium 50 mM 6 hrs, larvae L3
18
Cadmium 50 mM 12 hrs, larvae L3
15
Cadmium 50 mM 48 hrs, 4-day adult
21
Cadmium 100 mM 48 hrs, 4-day adult
29
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
23
Zinc 5 mM 12 hrs, larvae L3
6
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
37
Ethanol 5% 3 hrs, larvae L3
19
Ethanol 10% 3 hrs, larvae L3
16
Caffeine 1.5 mg/ml 4 hrs, larvae L3
16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
28
Caffeine 25 mg/ml 48 hrs, 4-day adult
10
Paraquat 5 mM 48 hrs, 4-day adult
31
Paraquat 10 mM 48 hrs, 4-day adult
37
Rotenone 2 μg 12 hrs, larvae L3
21
Rotenone 8 μg 12 hrs, larvae L3
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
9
cold shock, 4-day adult
7
heat shock, 4-day adult
25
Cadmium 50 mM 6 hrs, larvae L3
18
Cadmium 50 mM 12 hrs, larvae L3
15
Cadmium 50 mM 48 hrs, 4-day adult
21
Cadmium 100 mM 48 hrs, 4-day adult
29
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
23
Zinc 5 mM 12 hrs, larvae L3
6
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
(37)
Ethanol 5% 3 hrs, larvae L3
19
Ethanol 10% 3 hrs, larvae L3
16
Caffeine 1.5 mg/ml 4 hrs, larvae L3
16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
28
Caffeine 25 mg/ml 48 hrs, 4-day adult
10
Paraquat 5 mM 48 hrs, 4-day adult
31
Paraquat 10 mM 48 hrs, 4-day adult
(37)
Rotenone 2 μg 12 hrs, larvae L3
21
Rotenone 8 μg 12 hrs, larvae L3
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
9
cold shock, 4-day adult
7
heat shock, 4-day adult
25
Cadmium 50 mM 6 hrs, larvae L3
18
Cadmium 50 mM 12 hrs, larvae L3
15
Cadmium 50 mM 48 hrs, 4-day adult
21
Cadmium 100 mM 48 hrs, 4-day adult
29
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
23
Zinc 5 mM 12 hrs, larvae L3
6
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
37
Ethanol 5% 3 hrs, larvae L3
19
Ethanol 10% 3 hrs, larvae L3
16
Caffeine 1.5 mg/ml 4 hrs, larvae L3
16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
28
Caffeine 25 mg/ml 48 hrs, 4-day adult
10
Paraquat 5 mM 48 hrs, 4-day adult
31
Paraquat 10 mM 48 hrs, 4-day adult
37
Rotenone 2 μg 12 hrs, larvae L3
21
Rotenone 8 μg 12 hrs, larvae L3
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
9
cold shock, 4-day adult
7
heat shock, 4-day adult
25
Cadmium 50 mM 6 hrs, larvae L3
18
Cadmium 50 mM 12 hrs, larvae L3
15
Cadmium 50 mM 48 hrs, 4-day adult
21
Cadmium 100 mM 48 hrs, 4-day adult
29
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
23
Zinc 5 mM 12 hrs, larvae L3
6
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
37
Ethanol 5% 3 hrs, larvae L3
19
Ethanol 10% 3 hrs, larvae L3
16
Caffeine 1.5 mg/ml 4 hrs, larvae L3
16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
28
Caffeine 25 mg/ml 48 hrs, 4-day adult
10
Paraquat 5 mM 48 hrs, 4-day adult
31
Paraquat 10 mM 48 hrs, 4-day adult
37
Rotenone 2 μg 12 hrs, larvae L3
21
Rotenone 8 μg 12 hrs, larvae L3
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 1 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 4 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Transgenic Constructs & Insertions
Transgenic Constructs Insertions Gene Ontology: Function, Process
& Cellular Component ( 1 unique term ) Terms Based on
Experimental Evidence ( 0 terms ) Terms Based on Predictions or
Assertions ( 1 term ) Molecular Function ( 0 terms) Biological Process ( 0 terms) Cellular Component Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (40)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG6RNBTR )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG6FTW7N )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG6RFJNS )
Apis mellifera
Western honey bee
Amel\GB50470
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG010551
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH15078
Atta cephalotes
Leafcutter ant
Acep\ACEP27136
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO16214
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL21765
Linepithema humile
Argentine ant
Lhum\LH23268
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB13487
Solenopsis invicta
Red fire ant
Sinv\SINV23533
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG6ZKH2J )
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa
(EOG6VXDXZ )
Caenorhabditis elegans
Nematode
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Xenopus tropicalis
Western clawed frog
Gallus gallus
Domestic chicken
Rattus norvegicus
Norway rat
Human Orthologs (1)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 4 )Bloomington VDRC Genomic Clones ( 1 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 119 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for database merge of Source for merge of: CG2943 NEST:bs09f06
Additional comments Source for merge of CG2943 NEST:bs09f06 was sequence comparison (date:031021).
Other Comments External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
Linkouts
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 2 )Reported As Symbol Synonym Name Synonym Secondary FlyBase
IDs References ( 18 )Research paper Baycin-Hizal et al., 2011, J. Proteome Res. 10(6): 2777--2784GlycoFly: A Database of Drosophila N-linked Glycoproteins Identified Using SPEG-MS Techniques. [FBrf0213834] Blanco et al., 2010, BMC Dev. Biol. 10: 94Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Ellis and Carney, 2009, J. Evol. Biol. 22(11): 2183--2191Drosophila melanogaster males respond differently at the behavioural and genome-wide levels to Drosophila melanogaster and Drosophila simulans females. [FBrf0209694] Supplementary material Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] Guruharsha et al., 2011, Cell 147(3): Table S3. [FBrf0218395] Khanna et al., 2010, BMC Genomics 11(1): Towards a membrane proteome in Drosophila: a method for the isolation of plasma membrane. [FBrf0210978] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Personal communication to FlyBase Ni et al., 2010.12.1, A genome-scale shRNA resource for transgenic RNAi in Drosophila.A genome-scale shRNA resource for transgenic RNAi in Drosophila. [FBrf0212437] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi CenterRNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping projectDPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi CenterRNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Gene Disruption Project members, 2001-, (Computer file)(Computer file) [FBrf0132177] Oliver, 2001.8.16, Genome Res.: File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348 ). [FBrf0137492] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file)Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078] FlyBase analysis FlyBase, 1996-, FlyBase inference based on genome sequence analysis.FlyBase inference based on genome sequence analysis. [FBrf0104946] Stock list Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY.RNAi stocks available from NIG-FLY. [FBrf0218457]