Gene Dmel\CG2698

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General Information

Symbol

Dmel\CG2698

Species

D. melanogaster

Name

Annotation symbol

CG2698

Feature type

protein_coding_gene

FlyBase ID

FBgn0037536

Gene Model Status

Current

Stock availability

2 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

84E8-84E8

Sequence location

3R:3,827,284..3,831,755 [+]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG2698 (FBgn0037536). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Uncharacterised protein family UPF0118. Summary of modENCODE Temporal Expression Profile: Moderatey high expression at all stages of development. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, larval trachea, adult female reproductive system. Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1630981_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG2698. Gene sequence location is 3R:3827284..3831755.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

84E8-84E8

Limits computationally determined from genome sequence between P{EP}EP3060^EP3060 and P{PZ}grn⁰⁵⁹³⁰

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG2698 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.43

Gene model reviewed during 5.47

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.

DGC clone appears problematic (LD38235): incomplete CDS.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG2698-RA

FBtr0081784

NM_141499

3150

817

CG2698-RC

FBtr0308075

NM_001260046

3377

595

CG2698-RD

FBtr0308076

NM_001260047

2988

869

CG2698-RE

FBtr0335225

NM_001275430

3162

821

CG2698-RG

FBtr0335226

NM_001275431

3138

813

CG2698-RH

FBtr0335227

NM_001275432

2976

865

CG2698-RI

FBtr0335228

NM_001144552

3147

806

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG2698-PA

FBpp0081280

91.8

817

6.15

NP_649756

AAF54174

CG2698-PC

FBpp0300418

67.5

595

6.87

NP_001246975

AFH06294

CG2698-PD

FBpp0300419

97.7

869

6.31

NP_001246976

AFH06295

CG2698-PE

FBpp0307212

92.3

821

6.28

NP_001262359

AGB95741

CG2698-PG

FBpp0307213

91.4

813

6.23

NP_001262360

AGB95742

CG2698-PH

FBpp0307214

97.2

865

6.39

NP_001262361

AGB95743

CG2698-PI

FBpp0307215

90.6

806

6.39

NP_001138024

ACL83483

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Uncharacterised protein family UPF0118 (IPR002549)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

(Fisher et al., 2012)

Comment:maternally deposited

embryonic stage 4 -- 6

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 7 -- 8

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 11 -- 12

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 13 -- 16

organism | ubiquitous

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, larval trachea, adult female reproductive system. Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, adult male reproductive system, larval/adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		370.525
Larval Midgut		140.1
Larval Hindgut		262
Larval Malpighian Tubules		129.9
Larval Fat Body		434
Larval Salivary Gland		205.9
Larval Trachea		860.35
Larval Carcass		470.725
Adult Head		521.1
Adult Eye		955.425
Adult Brain		589.6
Adult Thoracic-Abdominal Ganglion		588.4
Adult Crop		453
Adult Midgut		128.6
Adult Hindgut		256.2
Adult Malpighian Tubules		180.4
Adult Fat Body		465
Adult Salivary Gland		244.7
Adult Heart		423.05
Adult VirginFemale Spermatheca		576.9
Adult InseminatedFemale Spermatheca		682.6
Adult Ovary		524.8
Adult Testis		359.2
Adult Male Accessory Gland		290.1
Adult Carcass		381
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		370.525
Larval Midgut		140.1
Larval Hindgut		262
Larval Malpighian Tubules		129.9
Larval Fat Body		434
Larval Salivary Gland		205.9
Larval Trachea		(860.35)
Larval Carcass		470.725
Adult Head		521.1
Adult Eye		(955.425)
Adult Brain		(589.6)
Adult Thoracic-Abdominal Ganglion		(588.4)
Adult Crop		453
Adult Midgut		128.6
Adult Hindgut		256.2
Adult Malpighian Tubules		180.4
Adult Fat Body		465
Adult Salivary Gland		244.7
Adult Heart		423.05
Adult VirginFemale Spermatheca		(576.9)
Adult InseminatedFemale Spermatheca		(682.6)
Adult Ovary		524.8
Adult Testis		359.2
Adult Male Accessory Gland		290.1
Adult Carcass		381
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		370.525
Larval Midgut		140.1
Larval Hindgut		262
Larval Malpighian Tubules		129.9
Larval Fat Body		434
Larval Salivary Gland		205.9
Larval Trachea		860.35
Larval Carcass		470.725
Adult Head		521.1
Adult Eye		955.425
Adult Brain		589.6
Adult Thoracic-Abdominal Ganglion		588.4
Adult Crop		453
Adult Midgut		128.6
Adult Hindgut		256.2
Adult Malpighian Tubules		180.4
Adult Fat Body		465
Adult Salivary Gland		244.7
Adult Heart		423.05
Adult VirginFemale Spermatheca		576.9
Adult InseminatedFemale Spermatheca		682.6
Adult Ovary		524.8
Adult Testis		359.2
Adult Male Accessory Gland		290.1
Adult Carcass		381
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		370.525
Larval Midgut		140.1
Larval Hindgut		262
Larval Malpighian Tubules		129.9
Larval Fat Body		434
Larval Salivary Gland		205.9
Larval Trachea		860.35
Larval Carcass		470.725
Adult Head		521.1
Adult Eye		955.425
Adult Brain		589.6
Adult Thoracic-Abdominal Ganglion		588.4
Adult Crop		453
Adult Midgut		128.6
Adult Hindgut		256.2
Adult Malpighian Tubules		180.4
Adult Fat Body		465
Adult Salivary Gland		244.7
Adult Heart		423.05
Adult VirginFemale Spermatheca		576.9
Adult InseminatedFemale Spermatheca		682.6
Adult Ovary		524.8
Adult Testis		359.2
Adult Male Accessory Gland		290.1
Adult Carcass		381
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		370.525
Larval Midgut		140.1
Larval Hindgut		262
Larval Malpighian Tubules		129.9
Larval Fat Body		434
Larval Salivary Gland		205.9
Larval Trachea		860.35
Larval Carcass		470.725
Adult Head		521.1
Adult Eye		955.425
Adult Brain		589.6
Adult Thoracic-Abdominal Ganglion		588.4
Adult Crop		453
Adult Midgut		128.6
Adult Hindgut		256.2
Adult Malpighian Tubules		180.4
Adult Fat Body		465
Adult Salivary Gland		244.7
Adult Heart		423.05
Adult VirginFemale Spermatheca		576.9
Adult InseminatedFemale Spermatheca		682.6
Adult Ovary		524.8
Adult Testis		359.2
Adult Male Accessory Gland		290.1
Adult Carcass		381
Expression Level Scale		None Low Moderate High Very high

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		370.525
Larval Midgut		140.1
Larval Hindgut		262
Larval Malpighian Tubules		129.9
Larval Fat Body		434
Larval Salivary Gland		205.9
Larval Trachea		(860.35)
Larval Carcass		470.725
Adult Head		521.1
Adult Eye		(955.425)
Adult Brain		589.6
Adult Thoracic-Abdominal Ganglion		588.4
Adult Crop		453
Adult Midgut		128.6
Adult Hindgut		256.2
Adult Malpighian Tubules		180.4
Adult Fat Body		465
Adult Salivary Gland		244.7
Adult Heart		423.05
Adult VirginFemale Spermatheca		576.9
Adult InseminatedFemale Spermatheca		682.6
Adult Ovary		524.8
Adult Testis		359.2
Adult Male Accessory Gland		290.1
Adult Carcass		381
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		370.525
Larval Midgut		140.1
Larval Hindgut		262
Larval Malpighian Tubules		129.9
Larval Fat Body		434
Larval Salivary Gland		205.9
Larval Trachea		860.35
Larval Carcass		470.725
Adult Head		521.1
Adult Eye		955.425
Adult Brain		589.6
Adult Thoracic-Abdominal Ganglion		588.4
Adult Crop		453
Adult Midgut		128.6
Adult Hindgut		256.2
Adult Malpighian Tubules		180.4
Adult Fat Body		465
Adult Salivary Gland		244.7
Adult Heart		423.05
Adult VirginFemale Spermatheca		576.9
Adult InseminatedFemale Spermatheca		682.6
Adult Ovary		524.8
Adult Testis		359.2
Adult Male Accessory Gland		290.1
Adult Carcass		381
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		370.525
Larval Midgut		140.1
Larval Hindgut		262
Larval Malpighian Tubules		129.9
Larval Fat Body		434
Larval Salivary Gland		205.9
Larval Trachea		860.35
Larval Carcass		470.725
Adult Head		521.1
Adult Eye		955.425
Adult Brain		589.6
Adult Thoracic-Abdominal Ganglion		588.4
Adult Crop		453
Adult Midgut		128.6
Adult Hindgut		256.2
Adult Malpighian Tubules		180.4
Adult Fat Body		465
Adult Salivary Gland		244.7
Adult Heart		423.05
Adult VirginFemale Spermatheca		576.9
Adult InseminatedFemale Spermatheca		682.6
Adult Ovary		524.8
Adult Testis		359.2
Adult Male Accessory Gland		290.1
Adult Carcass		381
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	521.1
NA	Eye	955.425
NA	Brain	589.6
370.525	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	588.4
NA	Crop	453
140.1	Midgut	128.6
262	Hindgut	256.2
129.9	Malpighian Tubules	180.4
434	Fat Body	465
205.9	Salivary Gland	244.7
NA	Heart	423.05
860.35	Trachea	NA
NA	VirginFemale Spermatheca	576.9
NA	InseminatedFemale Spermatheca	682.6
NA	Ovary	524.8
NA	Testis	359.2
NA	Male Accessory Gland	290.1
470.725	Carcass	381

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		18
central nervous system, larvae L3		9
central nervous system, pupae P8		10
head, virgin 1-day female		13
head, virgin 4-day female		14
head, virgin 20-day female		18
head, mated 1-day female		9
head, mated 4-day female		15
head, mated 20-day female		13
head, mated 1-day male		17
head, mated 4-day male		22
head, mated 20-day male		29
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		6
digestive system, 1-day adult		5
digestive system, 4-day adult		5
digestive system, 20-day adult		5
fat body, larvae L3 wandering		3
fat body, white prepupae		7
fat body, pupae P8		11
carcass, larvae L3 wandering		18
carcass, 1-day adult		7
carcass, 4-day adult		10
carcass, 20-day adult		10
ovary, virgin 4-day female		25
ovary, mated 4-day female		19
testis, mated 4-day male		18
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		18
central nervous system, larvae L3		9
central nervous system, pupae P8		10
head, virgin 1-day female		13
head, virgin 4-day female		14
head, virgin 20-day female		18
head, mated 1-day female		9
head, mated 4-day female		15
head, mated 20-day female		13
head, mated 1-day male		17
head, mated 4-day male		22
head, mated 20-day male		(29)
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		6
digestive system, 1-day adult		5
digestive system, 4-day adult		5
digestive system, 20-day adult		5
fat body, larvae L3 wandering		3
fat body, white prepupae		7
fat body, pupae P8		11
carcass, larvae L3 wandering		18
carcass, 1-day adult		7
carcass, 4-day adult		10
carcass, 20-day adult		10
ovary, virgin 4-day female		25
ovary, mated 4-day female		19
testis, mated 4-day male		18
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		18
central nervous system, larvae L3		9
central nervous system, pupae P8		10
head, virgin 1-day female		13
head, virgin 4-day female		14
head, virgin 20-day female		18
head, mated 1-day female		9
head, mated 4-day female		15
head, mated 20-day female		13
head, mated 1-day male		17
head, mated 4-day male		22
head, mated 20-day male		29
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		6
digestive system, 1-day adult		5
digestive system, 4-day adult		5
digestive system, 20-day adult		5
fat body, larvae L3 wandering		3
fat body, white prepupae		7
fat body, pupae P8		11
carcass, larvae L3 wandering		18
carcass, 1-day adult		7
carcass, 4-day adult		10
carcass, 20-day adult		10
ovary, virgin 4-day female		25
ovary, mated 4-day female		19
testis, mated 4-day male		18
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		18
central nervous system, larvae L3		9
central nervous system, pupae P8		10
head, virgin 1-day female		13
head, virgin 4-day female		14
head, virgin 20-day female		18
head, mated 1-day female		9
head, mated 4-day female		15
head, mated 20-day female		13
head, mated 1-day male		17
head, mated 4-day male		22
head, mated 20-day male		29
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		6
digestive system, 1-day adult		5
digestive system, 4-day adult		5
digestive system, 20-day adult		5
fat body, larvae L3 wandering		3
fat body, white prepupae		7
fat body, pupae P8		11
carcass, larvae L3 wandering		18
carcass, 1-day adult		7
carcass, 4-day adult		10
carcass, 20-day adult		10
ovary, virgin 4-day female		25
ovary, mated 4-day female		19
testis, mated 4-day male		18
accessory gland, mated 4-day male		6
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		18
central nervous system, larvae L3		9
central nervous system, pupae P8		10
head, virgin 1-day female		13
head, virgin 4-day female		14
head, virgin 20-day female		18
head, mated 1-day female		9
head, mated 4-day female		15
head, mated 20-day female		13
head, mated 1-day male		17
head, mated 4-day male		22
head, mated 20-day male		29
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		6
digestive system, 1-day adult		5
digestive system, 4-day adult		5
digestive system, 20-day adult		5
fat body, larvae L3 wandering		3
fat body, white prepupae		7
fat body, pupae P8		11
carcass, larvae L3 wandering		18
carcass, 1-day adult		7
carcass, 4-day adult		10
carcass, 20-day adult		10
ovary, virgin 4-day female		25
ovary, mated 4-day female		19
testis, mated 4-day male		18
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		18
central nervous system, larvae L3		9
central nervous system, pupae P8		10
head, virgin 1-day female		13
head, virgin 4-day female		14
head, virgin 20-day female		18
head, mated 1-day female		9
head, mated 4-day female		15
head, mated 20-day female		13
head, mated 1-day male		17
head, mated 4-day male		22
head, mated 20-day male		29
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		6
digestive system, 1-day adult		5
digestive system, 4-day adult		5
digestive system, 20-day adult		5
fat body, larvae L3 wandering		3
fat body, white prepupae		7
fat body, pupae P8		11
carcass, larvae L3 wandering		18
carcass, 1-day adult		7
carcass, 4-day adult		10
carcass, 20-day adult		10
ovary, virgin 4-day female		25
ovary, mated 4-day female		19
testis, mated 4-day male		18
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		18
central nervous system, larvae L3		9
central nervous system, pupae P8		10
head, virgin 1-day female		13
head, virgin 4-day female		14
head, virgin 20-day female		18
head, mated 1-day female		9
head, mated 4-day female		15
head, mated 20-day female		13
head, mated 1-day male		17
head, mated 4-day male		22
head, mated 20-day male		29
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		6
digestive system, 1-day adult		5
digestive system, 4-day adult		5
digestive system, 20-day adult		5
fat body, larvae L3 wandering		3
fat body, white prepupae		7
fat body, pupae P8		11
carcass, larvae L3 wandering		18
carcass, 1-day adult		7
carcass, 4-day adult		10
carcass, 20-day adult		10
ovary, virgin 4-day female		25
ovary, mated 4-day female		19
testis, mated 4-day male		18
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		18
central nervous system, larvae L3		9
central nervous system, pupae P8		10
head, virgin 1-day female		13
head, virgin 4-day female		14
head, virgin 20-day female		18
head, mated 1-day female		9
head, mated 4-day female		15
head, mated 20-day female		13
head, mated 1-day male		17
head, mated 4-day male		22
head, mated 20-day male		29
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		6
digestive system, 1-day adult		5
digestive system, 4-day adult		5
digestive system, 20-day adult		5
fat body, larvae L3 wandering		3
fat body, white prepupae		7
fat body, pupae P8		11
carcass, larvae L3 wandering		18
carcass, 1-day adult		7
carcass, 4-day adult		10
carcass, 20-day adult		10
ovary, virgin 4-day female		25
ovary, mated 4-day female		19
testis, mated 4-day male		18
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Moderatey high expression at all stages of development.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		32
embryo 02-04hr		31
embryo 04-06hr		22
embryo 06-08hr		23
embryo 08-10hr		27
embryo 10-12hr		26
embryo 12-14hr		23
embryo 14-16hr		21
embryo 16-18hr		26
embryo 18-20hr		26
embryo 20-22hr		28
embryo 22-24hr		37
larva L1		25
larva L2		17
larva L3 12hr old		20
larva L3 puffstage 1-2		22
larva L3 puffstage 3-6		27
larva L3 puffstage 7-9		29
white prepupae new		23
white prepupae 12hr		25
white prepupae 24hr		26
pupae 2d postWPP		23
pupae 3d postWPP		26
pupae 4d postWPP		21
adult male 01day		28
adult male 05day		34
adult male 30day		32
adult female 01day		22
adult female 05day		29
adult female 30day		27
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(32)
embryo 02-04hr		(31)
embryo 04-06hr		22
embryo 06-08hr		23
embryo 08-10hr		(27)
embryo 10-12hr		26
embryo 12-14hr		23
embryo 14-16hr		21
embryo 16-18hr		26
embryo 18-20hr		26
embryo 20-22hr		(28)
embryo 22-24hr		(37)
larva L1		25
larva L2		17
larva L3 12hr old		20
larva L3 puffstage 1-2		22
larva L3 puffstage 3-6		(27)
larva L3 puffstage 7-9		(29)
white prepupae new		23
white prepupae 12hr		25
white prepupae 24hr		26
pupae 2d postWPP		23
pupae 3d postWPP		26
pupae 4d postWPP		21
adult male 01day		(28)
adult male 05day		(34)
adult male 30day		(32)
adult female 01day		22
adult female 05day		(29)
adult female 30day		(27)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		32
embryo 02-04hr		31
embryo 04-06hr		22
embryo 06-08hr		23
embryo 08-10hr		27
embryo 10-12hr		26
embryo 12-14hr		23
embryo 14-16hr		21
embryo 16-18hr		26
embryo 18-20hr		26
embryo 20-22hr		28
embryo 22-24hr		37
larva L1		25
larva L2		17
larva L3 12hr old		20
larva L3 puffstage 1-2		22
larva L3 puffstage 3-6		27
larva L3 puffstage 7-9		29
white prepupae new		23
white prepupae 12hr		25
white prepupae 24hr		26
pupae 2d postWPP		23
pupae 3d postWPP		26
pupae 4d postWPP		21
adult male 01day		28
adult male 05day		34
adult male 30day		32
adult female 01day		22
adult female 05day		29
adult female 30day		27
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		32
embryo 02-04hr		31
embryo 04-06hr		22
embryo 06-08hr		23
embryo 08-10hr		27
embryo 10-12hr		26
embryo 12-14hr		23
embryo 14-16hr		21
embryo 16-18hr		26
embryo 18-20hr		26
embryo 20-22hr		28
embryo 22-24hr		37
larva L1		25
larva L2		17
larva L3 12hr old		20
larva L3 puffstage 1-2		22
larva L3 puffstage 3-6		27
larva L3 puffstage 7-9		29
white prepupae new		23
white prepupae 12hr		25
white prepupae 24hr		26
pupae 2d postWPP		23
pupae 3d postWPP		26
pupae 4d postWPP		21
adult male 01day		28
adult male 05day		34
adult male 30day		32
adult female 01day		22
adult female 05day		29
adult female 30day		27
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		32
embryo 02-04hr		31
embryo 04-06hr		22
embryo 06-08hr		23
embryo 08-10hr		27
embryo 10-12hr		26
embryo 12-14hr		23
embryo 14-16hr		21
embryo 16-18hr		26
embryo 18-20hr		26
embryo 20-22hr		28
embryo 22-24hr		37
larva L1		25
larva L2		17
larva L3 12hr old		20
larva L3 puffstage 1-2		22
larva L3 puffstage 3-6		27
larva L3 puffstage 7-9		29
white prepupae new		23
white prepupae 12hr		25
white prepupae 24hr		26
pupae 2d postWPP		23
pupae 3d postWPP		26
pupae 4d postWPP		21
adult male 01day		28
adult male 05day		34
adult male 30day		32
adult female 01day		22
adult female 05day		29
adult female 30day		27
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		32
embryo 02-04hr		31
embryo 04-06hr		22
embryo 06-08hr		23
embryo 08-10hr		27
embryo 10-12hr		26
embryo 12-14hr		23
embryo 14-16hr		21
embryo 16-18hr		26
embryo 18-20hr		26
embryo 20-22hr		28
embryo 22-24hr		(37)
larva L1		25
larva L2		17
larva L3 12hr old		20
larva L3 puffstage 1-2		22
larva L3 puffstage 3-6		27
larva L3 puffstage 7-9		29
white prepupae new		23
white prepupae 12hr		25
white prepupae 24hr		26
pupae 2d postWPP		23
pupae 3d postWPP		26
pupae 4d postWPP		21
adult male 01day		28
adult male 05day		(34)
adult male 30day		32
adult female 01day		22
adult female 05day		29
adult female 30day		27
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		32
embryo 02-04hr		31
embryo 04-06hr		22
embryo 06-08hr		23
embryo 08-10hr		27
embryo 10-12hr		26
embryo 12-14hr		23
embryo 14-16hr		21
embryo 16-18hr		26
embryo 18-20hr		26
embryo 20-22hr		28
embryo 22-24hr		37
larva L1		25
larva L2		17
larva L3 12hr old		20
larva L3 puffstage 1-2		22
larva L3 puffstage 3-6		27
larva L3 puffstage 7-9		29
white prepupae new		23
white prepupae 12hr		25
white prepupae 24hr		26
pupae 2d postWPP		23
pupae 3d postWPP		26
pupae 4d postWPP		21
adult male 01day		28
adult male 05day		34
adult male 30day		32
adult female 01day		22
adult female 05day		29
adult female 30day		27
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		32
embryo 02-04hr		31
embryo 04-06hr		22
embryo 06-08hr		23
embryo 08-10hr		27
embryo 10-12hr		26
embryo 12-14hr		23
embryo 14-16hr		21
embryo 16-18hr		26
embryo 18-20hr		26
embryo 20-22hr		28
embryo 22-24hr		37
larva L1		25
larva L2		17
larva L3 12hr old		20
larva L3 puffstage 1-2		22
larva L3 puffstage 3-6		27
larva L3 puffstage 7-9		29
white prepupae new		23
white prepupae 12hr		25
white prepupae 24hr		26
pupae 2d postWPP		23
pupae 3d postWPP		26
pupae 4d postWPP		21
adult male 01day		28
adult male 05day		34
adult male 30day		32
adult female 01day		22
adult female 05day		29
adult female 30day		27
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		26
Schneider line 2 Sg4		23
embryonic 1182-4H		26
embryonic GM2		38
embryonic Kc167		28
embryonic S1		22
embryonic S3		14
leg disc CME L1		15
wing disc CME-W2		27
wing disc ML-DmD8		27
wing disc ML-DmD9		22
wing disc ML-DmD16-c3		10
wing disc ML-DmD21		19
wing disc ML-DmD32		23
haltere disc ML-DmD17-c3		32
eye-antennal disc ML-DmD11		18
antennal disc ML-DmD20-c5		24
mixed discs ML-DmD4-c1		16
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		39
tumorous blood cells mbn2		22
ovary fGS/OSS		19
ovary OSC		12
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		26
Schneider line 2 Sg4		23
embryonic 1182-4H		26
embryonic GM2		(38)
embryonic Kc167		(28)
embryonic S1		22
embryonic S3		14
leg disc CME L1		15
wing disc CME-W2		(27)
wing disc ML-DmD8		(27)
wing disc ML-DmD9		22
wing disc ML-DmD16-c3		10
wing disc ML-DmD21		19
wing disc ML-DmD32		23
haltere disc ML-DmD17-c3		(32)
eye-antennal disc ML-DmD11		18
antennal disc ML-DmD20-c5		24
mixed discs ML-DmD4-c1		16
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		(39)
tumorous blood cells mbn2		22
ovary fGS/OSS		19
ovary OSC		12
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		26
Schneider line 2 Sg4		23
embryonic 1182-4H		26
embryonic GM2		38
embryonic Kc167		28
embryonic S1		22
embryonic S3		14
leg disc CME L1		15
wing disc CME-W2		27
wing disc ML-DmD8		27
wing disc ML-DmD9		22
wing disc ML-DmD16-c3		10
wing disc ML-DmD21		19
wing disc ML-DmD32		23
haltere disc ML-DmD17-c3		32
eye-antennal disc ML-DmD11		18
antennal disc ML-DmD20-c5		24
mixed discs ML-DmD4-c1		16
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		39
tumorous blood cells mbn2		22
ovary fGS/OSS		19
ovary OSC		12
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		26
Schneider line 2 Sg4		23
embryonic 1182-4H		26
embryonic GM2		38
embryonic Kc167		28
embryonic S1		22
embryonic S3		14
leg disc CME L1		15
wing disc CME-W2		27
wing disc ML-DmD8		27
wing disc ML-DmD9		22
wing disc ML-DmD16-c3		10
wing disc ML-DmD21		19
wing disc ML-DmD32		23
haltere disc ML-DmD17-c3		32
eye-antennal disc ML-DmD11		18
antennal disc ML-DmD20-c5		24
mixed discs ML-DmD4-c1		16
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		39
tumorous blood cells mbn2		22
ovary fGS/OSS		19
ovary OSC		12
ovary OSS		7
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		26
Schneider line 2 Sg4		23
embryonic 1182-4H		26
embryonic GM2		38
embryonic Kc167		28
embryonic S1		22
embryonic S3		14
leg disc CME L1		15
wing disc CME-W2		27
wing disc ML-DmD8		27
wing disc ML-DmD9		22
wing disc ML-DmD16-c3		10
wing disc ML-DmD21		19
wing disc ML-DmD32		23
haltere disc ML-DmD17-c3		32
eye-antennal disc ML-DmD11		18
antennal disc ML-DmD20-c5		24
mixed discs ML-DmD4-c1		16
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		39
tumorous blood cells mbn2		22
ovary fGS/OSS		19
ovary OSC		12
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		26
Schneider line 2 Sg4		23
embryonic 1182-4H		26
embryonic GM2		(38)
embryonic Kc167		28
embryonic S1		22
embryonic S3		14
leg disc CME L1		15
wing disc CME-W2		27
wing disc ML-DmD8		27
wing disc ML-DmD9		22
wing disc ML-DmD16-c3		10
wing disc ML-DmD21		19
wing disc ML-DmD32		23
haltere disc ML-DmD17-c3		32
eye-antennal disc ML-DmD11		18
antennal disc ML-DmD20-c5		24
mixed discs ML-DmD4-c1		16
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		(39)
tumorous blood cells mbn2		22
ovary fGS/OSS		19
ovary OSC		12
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		26
Schneider line 2 Sg4		23
embryonic 1182-4H		26
embryonic GM2		38
embryonic Kc167		28
embryonic S1		22
embryonic S3		14
leg disc CME L1		15
wing disc CME-W2		27
wing disc ML-DmD8		27
wing disc ML-DmD9		22
wing disc ML-DmD16-c3		10
wing disc ML-DmD21		19
wing disc ML-DmD32		23
haltere disc ML-DmD17-c3		32
eye-antennal disc ML-DmD11		18
antennal disc ML-DmD20-c5		24
mixed discs ML-DmD4-c1		16
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		39
tumorous blood cells mbn2		22
ovary fGS/OSS		19
ovary OSC		12
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		26
Schneider line 2 Sg4		23
embryonic 1182-4H		26
embryonic GM2		38
embryonic Kc167		28
embryonic S1		22
embryonic S3		14
leg disc CME L1		15
wing disc CME-W2		27
wing disc ML-DmD8		27
wing disc ML-DmD9		22
wing disc ML-DmD16-c3		10
wing disc ML-DmD21		19
wing disc ML-DmD32		23
haltere disc ML-DmD17-c3		32
eye-antennal disc ML-DmD11		18
antennal disc ML-DmD20-c5		24
mixed discs ML-DmD4-c1		16
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		39
tumorous blood cells mbn2		22
ovary fGS/OSS		19
ovary OSC		12
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		4
heat shock, 4-day adult		14
Cadmium 50 mM 6 hrs, larvae L3		10
Cadmium 50 mM 12 hrs, larvae L3		16
Cadmium 50 mM 48 hrs, 4-day adult		13
Cadmium 100 mM 48 hrs, 4-day adult		17
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		14
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		13
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		16
Ethanol 10% 3 hrs, larvae L3		11
Caffeine 1.5 mg/ml 4 hrs, larvae L3		19
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		19
Caffeine 25 mg/ml 48 hrs, 4-day adult		5
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		23
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		10
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		4
heat shock, 4-day adult		14
Cadmium 50 mM 6 hrs, larvae L3		10
Cadmium 50 mM 12 hrs, larvae L3		16
Cadmium 50 mM 48 hrs, 4-day adult		13
Cadmium 100 mM 48 hrs, 4-day adult		17
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		14
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		13
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		16
Ethanol 10% 3 hrs, larvae L3		11
Caffeine 1.5 mg/ml 4 hrs, larvae L3		19
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		19
Caffeine 25 mg/ml 48 hrs, 4-day adult		5
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		23
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		10
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		4
heat shock, 4-day adult		14
Cadmium 50 mM 6 hrs, larvae L3		10
Cadmium 50 mM 12 hrs, larvae L3		16
Cadmium 50 mM 48 hrs, 4-day adult		13
Cadmium 100 mM 48 hrs, 4-day adult		17
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		14
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		13
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		16
Ethanol 10% 3 hrs, larvae L3		11
Caffeine 1.5 mg/ml 4 hrs, larvae L3		19
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		19
Caffeine 25 mg/ml 48 hrs, 4-day adult		5
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		23
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		4
heat shock, 4-day adult		14
Cadmium 50 mM 6 hrs, larvae L3		10
Cadmium 50 mM 12 hrs, larvae L3		16
Cadmium 50 mM 48 hrs, 4-day adult		13
Cadmium 100 mM 48 hrs, 4-day adult		17
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		14
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		13
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		16
Ethanol 10% 3 hrs, larvae L3		11
Caffeine 1.5 mg/ml 4 hrs, larvae L3		19
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		19
Caffeine 25 mg/ml 48 hrs, 4-day adult		5
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		23
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		10
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		4
heat shock, 4-day adult		14
Cadmium 50 mM 6 hrs, larvae L3		10
Cadmium 50 mM 12 hrs, larvae L3		16
Cadmium 50 mM 48 hrs, 4-day adult		13
Cadmium 100 mM 48 hrs, 4-day adult		17
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		14
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		13
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		16
Ethanol 10% 3 hrs, larvae L3		11
Caffeine 1.5 mg/ml 4 hrs, larvae L3		19
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		19
Caffeine 25 mg/ml 48 hrs, 4-day adult		5
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		23
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		10
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		4
heat shock, 4-day adult		14
Cadmium 50 mM 6 hrs, larvae L3		10
Cadmium 50 mM 12 hrs, larvae L3		16
Cadmium 50 mM 48 hrs, 4-day adult		13
Cadmium 100 mM 48 hrs, 4-day adult		17
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		14
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		13
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		16
Ethanol 10% 3 hrs, larvae L3		11
Caffeine 1.5 mg/ml 4 hrs, larvae L3		19
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		19
Caffeine 25 mg/ml 48 hrs, 4-day adult		5
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		23
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		10
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		4
heat shock, 4-day adult		14
Cadmium 50 mM 6 hrs, larvae L3		10
Cadmium 50 mM 12 hrs, larvae L3		16
Cadmium 50 mM 48 hrs, 4-day adult		13
Cadmium 100 mM 48 hrs, 4-day adult		17
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		14
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		13
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		16
Ethanol 10% 3 hrs, larvae L3		11
Caffeine 1.5 mg/ml 4 hrs, larvae L3		19
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		19
Caffeine 25 mg/ml 48 hrs, 4-day adult		5
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		23
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		4
heat shock, 4-day adult		14
Cadmium 50 mM 6 hrs, larvae L3		10
Cadmium 50 mM 12 hrs, larvae L3		16
Cadmium 50 mM 48 hrs, 4-day adult		13
Cadmium 100 mM 48 hrs, 4-day adult		17
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		14
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		13
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		16
Ethanol 10% 3 hrs, larvae L3		11
Caffeine 1.5 mg/ml 4 hrs, larvae L3		19
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		19
Caffeine 25 mg/ml 48 hrs, 4-day adult		5
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		23
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

BDGP expression data

•

RE12611

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0037536

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG2698-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable

Sterility

Allele

fertile

CG2698^c03200

Phenotype manifest in

Allele

Classical Alleles ( 2 )

For All Classical Alleles Show

Allele of CG2698	Class	Mutagen	Stocks	Known lesion
CG2698^c03200		piggyBac transposase	2	--
CG2698^CB03026		P-element activity	0	Yes

Alleles Carried on Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG2698	Class	Mutagen	Stocks	Known lesion
CG2698^GD2855		in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Disrupted in

Df(3R)Exel6263

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD2855}

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

P{PTT-GB}CG2698^CB03026

PBac{PB}CG2698^c03200

Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 0 terms )

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG2698 allele

Gene

References

External Data

Linkouts

BioGRID - A database of protein and genetic interactions

•

66130

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0037536

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

40945

Orthologs

OrthoDB Orthologs (41) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG6HT9BN

Dipteran inclusive ortholog search

EOG6JDHFW

Insect inclusive ortholog search

EOG6CFZ46

Arthropod inclusive ortholog search

EOG6GB5N5

Metazoa inclusive ortholog search

EOG6SR8PP

Orthologs in Drosophila Species (EOG6HT9BN)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA15434

Drosophila persimilis

Dper\GL24454

Drosophila willistoni

Dwil\GK13068

Drosophila virilis

Dvir\GJ14284

Drosophila mojavensis

Dmoj\GI24426

Drosophila grimshawi

Dgri\GH14051

Orthologs in non-Drosophila Dipterans (EOG6JDHFW)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL013335

Anopheles gambiae

Malaria mosquito

Agam\AGAP003409

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ003721

Orthologs in non-Dipteran Insects (EOG6CFZ46)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\GB42023

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG011037

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH22491

Atta cephalotes

Leafcutter ant

Acep\ACEP10598

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO16741

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL19382

Linepithema humile

Argentine ant

Lhum\LH20710

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB22978

Solenopsis invicta

Red fire ant

Sinv\SINV20154

Solenopsis invicta

Red fire ant

Sinv\SINV20150

Bombyx mori

Silkmoth

Bmor\BGIBMGA004902

Pediculus humanus

Human body louse

Phum\PHUM450430

Pediculus humanus

Human body louse

Phum\PHUM450310

Tribolium castaneum

Red flour beetle

Tcas\TC009562

Orthologs in non-Insect Arthropods (EOG6GB5N5)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Daphnia pulex

Water flea

Dpux\JGI_V11_308213

Ixodes scapularis

Deer tick

Isca\ISCW011433

Orthologs in non-Arthropod Metazoa (EOG6SR8PP)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Caenorhabditis elegans

Nematode

Cele\M01F1.4

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_028918gn

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_028006gn

Danio rerio

Zebrafish

Drer\ENSDARG00000090913

Danio rerio

Zebrafish

Drer\si:ch211-194b7.4

Xenopus tropicalis

Western clawed frog

Xtro\ENSXETG00000033754

Gallus gallus

Domestic chicken

Ggal\C9orf5

Mus musculus

House mouse

Mmus\D730040F13Rik

Rattus norvegicus

Norway rat

Rnor\RGD1308958

Homo sapiens

Human

Hsap\ENSG00000106771

Human Orthologs (1)

Gene

OMIM

HGNC

Hsap\ENSG00000106771

AAA Orthologs (11) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA15434

Drosophila persimilis

Dper\GL24454

Drosophila willistoni

Dwil\GK13068

Drosophila virilis

Dvir\GJ14284

Drosophila mojavensis

Dmoj\GI24426

Drosophila grimshawi

Dgri\GH14051

Stocks & Reagents

Stocks Listed in FlyBase ( 2 )

Bloomington

11196

w¹¹¹⁸; PBac{PB}CG2698^c03200

Harvard

PBac{PB}CG2698^c03200

Genomic Clones ( 1 )

BACR07M14

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 60 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0037536

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

40945

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

RefSeq (Proteins)

•

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

40945

UniProtKB/TrEMBL

•

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Uncharacterised protein family UPF0118 (IPR002549)

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

•

RE12611

Linkouts

BioGRID - A database of protein and genetic interactions

•

66130

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0037536

DRSC - Results from RNAi screens.

•

FBgn0037536

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0037536

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG2698-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0037536

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

40945

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

40945

modMine - Data generated by the modENCODE project.

•

FBgn0037536

Synonyms & Secondary IDs ( 1 )

Reported As

Symbol Synonym

CG2698

(Buszczak et al., 2007)

Name Synonym

Secondary FlyBase IDs

References ( 14 )

Research paper

Blanco et al., 2010, BMC Dev. Biol. 10: 94: Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812]
Buszczak et al., 2007, Genetics 175(3): 1505--1531: The Carnegie protein trap library: A versatile tool for Drosophila developmental studies. [FBrf0200345]

Supplementary material

Graveley et al., 2011, Nature 471(7339):: Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980]
The modENCODE Consortium, 2010, Science 330(6012):: DataS14: Gene co-expression clusters. [FBrf0213979]
Giot et al., 2003, Science 302(5651):: Tables S1 to S7. [FBrf0166452]

Personal communication to FlyBase

Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file): Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340]
Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase.: Exelixis insertion alleles that are not in FlyBase. [FBrf0179797]
Ryder, 2004.4.26, Exelixis CG deletion data.: Exelixis CG deletion data. [FBrf0184335]
Gene Disruption Project members, 2001-, (Computer file): (Computer file) [FBrf0132177]
BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file): Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]

FlyBase analysis

FlyBase, 1992-, FlyBase curation.: FlyBase curation. [FBrf0105495]

Website

Fisher et al., 2012, BDGP insitu homepage: BDGP insitu homepage [FBrf0219073]