General Information Symbol Dmel\ CG2767Species D. melanogaster Name Annotation symbol CG2767 Feature type protein_coding_gene FlyBase ID FBgn0037537 Gene Model Status Current Stock availability 5 publicly
available Genomic Location Chromosome (arm) 3R Recombination map Cytogenetic map 84E8-84E8 Sequence location 3R:3,831,646..3,833,832 [-]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information This gene is referred to in FlyBase by the symbol
Dmel\CG2767 (FBgn0037537). It is a protein_coding_gene from
Drosophila melanogaster . Based on sequence similarity, it is predicted to have
molecular function : alcohol dehydrogenase (NADP+) activity. There is experimental evidence that it is involved in the
biological process : chaeta development; wing disc development.
6 alleles are reported . No phenotypic data is available. It has
one annotated transcript and
one annotated polypeptide .
Protein features are: Aldo/keto reductase; Aldo/keto reductase subgroup; Aldo/keto reductase, conserved site; NADP-dependent oxidoreductase domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 06-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult crop, larval/adult hindgut, larval fat body, larval salivary gland, larval trachea, adult male accessory gland, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, larval/adult midgut, larval/adult Malpighian tubules, adult heart, adult fat body, adult salivary gland, adult female reproductive system, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1628404_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG2767. Gene sequence location is
3R:3831646..3833832 .
User Contributed Data
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FB2013_03
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.43
Gene model reviewed during 5.47
Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: maternally deposited
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
315.325
Larval Midgut
132.6
Larval Hindgut
638.7
Larval Malpighian Tubules
280.5
Larval Fat Body
2256.4
Larval Salivary Gland
772.3
Larval Trachea
1254.375
Larval Carcass
1197.975
Adult Head
755.7
Adult Eye
2651.75
Adult Brain
84.7
Adult Thoracic-Abdominal Ganglion
106.9
Adult Crop
2725.4
Adult Midgut
172.7
Adult Hindgut
886.3
Adult Malpighian Tubules
168.1
Adult Fat Body
418.1
Adult Salivary Gland
291.2
Adult Heart
305.025
Adult VirginFemale Spermatheca
366.5
Adult InseminatedFemale Spermatheca
396.2
Adult Ovary
244.7
Adult Testis
39.2
Adult Male Accessory Gland
613.9
Adult Carcass
356.2
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
315.325
Larval Midgut
132.6
Larval Hindgut
(638.7)
Larval Malpighian Tubules
280.5
Larval Fat Body
(2256.4)
Larval Salivary Gland
(772.3)
Larval Trachea
(1254.375)
Larval Carcass
(1197.975)
Adult Head
(755.7)
Adult Eye
(2651.75)
Adult Brain
84.7
Adult Thoracic-Abdominal Ganglion
106.9
Adult Crop
(2725.4)
Adult Midgut
172.7
Adult Hindgut
(886.3)
Adult Malpighian Tubules
168.1
Adult Fat Body
418.1
Adult Salivary Gland
291.2
Adult Heart
305.025
Adult VirginFemale Spermatheca
366.5
Adult InseminatedFemale Spermatheca
396.2
Adult Ovary
244.7
Adult Testis
39.2
Adult Male Accessory Gland
(613.9)
Adult Carcass
356.2
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
315.325
Larval Midgut
132.6
Larval Hindgut
638.7
Larval Malpighian Tubules
280.5
Larval Fat Body
(2256.4)
Larval Salivary Gland
772.3
Larval Trachea
(1254.375)
Larval Carcass
(1197.975)
Adult Head
755.7
Adult Eye
(2651.75)
Adult Brain
84.7
Adult Thoracic-Abdominal Ganglion
106.9
Adult Crop
(2725.4)
Adult Midgut
172.7
Adult Hindgut
886.3
Adult Malpighian Tubules
168.1
Adult Fat Body
418.1
Adult Salivary Gland
291.2
Adult Heart
305.025
Adult VirginFemale Spermatheca
366.5
Adult InseminatedFemale Spermatheca
396.2
Adult Ovary
244.7
Adult Testis
39.2
Adult Male Accessory Gland
613.9
Adult Carcass
356.2
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
315.325
Larval Midgut
132.6
Larval Hindgut
638.7
Larval Malpighian Tubules
280.5
Larval Fat Body
2256.4
Larval Salivary Gland
772.3
Larval Trachea
1254.375
Larval Carcass
1197.975
Adult Head
755.7
Adult Eye
2651.75
Adult Brain
84.7
Adult Thoracic-Abdominal Ganglion
106.9
Adult Crop
2725.4
Adult Midgut
172.7
Adult Hindgut
886.3
Adult Malpighian Tubules
168.1
Adult Fat Body
418.1
Adult Salivary Gland
291.2
Adult Heart
305.025
Adult VirginFemale Spermatheca
366.5
Adult InseminatedFemale Spermatheca
396.2
Adult Ovary
244.7
Adult Testis
39.2
Adult Male Accessory Gland
613.9
Adult Carcass
356.2
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
315.325
Larval Midgut
132.6
Larval Hindgut
638.7
Larval Malpighian Tubules
280.5
Larval Fat Body
2256.4
Larval Salivary Gland
772.3
Larval Trachea
1254.375
Larval Carcass
1197.975
Adult Head
755.7
Adult Eye
2651.75
Adult Brain
84.7
Adult Thoracic-Abdominal Ganglion
106.9
Adult Crop
2725.4
Adult Midgut
172.7
Adult Hindgut
886.3
Adult Malpighian Tubules
168.1
Adult Fat Body
418.1
Adult Salivary Gland
291.2
Adult Heart
305.025
Adult VirginFemale Spermatheca
366.5
Adult InseminatedFemale Spermatheca
396.2
Adult Ovary
244.7
Adult Testis
39.2
Adult Male Accessory Gland
613.9
Adult Carcass
356.2
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
315.325
Larval Midgut
132.6
Larval Hindgut
638.7
Larval Malpighian Tubules
280.5
Larval Fat Body
(2256.4)
Larval Salivary Gland
772.3
Larval Trachea
(1254.375)
Larval Carcass
(1197.975)
Adult Head
755.7
Adult Eye
(2651.75)
Adult Brain
84.7
Adult Thoracic-Abdominal Ganglion
106.9
Adult Crop
(2725.4)
Adult Midgut
172.7
Adult Hindgut
(886.3)
Adult Malpighian Tubules
168.1
Adult Fat Body
418.1
Adult Salivary Gland
291.2
Adult Heart
305.025
Adult VirginFemale Spermatheca
366.5
Adult InseminatedFemale Spermatheca
396.2
Adult Ovary
244.7
Adult Testis
39.2
Adult Male Accessory Gland
613.9
Adult Carcass
356.2
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
315.325
Larval Midgut
132.6
Larval Hindgut
638.7
Larval Malpighian Tubules
280.5
Larval Fat Body
(2256.4)
Larval Salivary Gland
772.3
Larval Trachea
1254.375
Larval Carcass
1197.975
Adult Head
755.7
Adult Eye
(2651.75)
Adult Brain
84.7
Adult Thoracic-Abdominal Ganglion
106.9
Adult Crop
(2725.4)
Adult Midgut
172.7
Adult Hindgut
886.3
Adult Malpighian Tubules
168.1
Adult Fat Body
418.1
Adult Salivary Gland
291.2
Adult Heart
305.025
Adult VirginFemale Spermatheca
366.5
Adult InseminatedFemale Spermatheca
396.2
Adult Ovary
244.7
Adult Testis
39.2
Adult Male Accessory Gland
613.9
Adult Carcass
356.2
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
315.325
Larval Midgut
132.6
Larval Hindgut
638.7
Larval Malpighian Tubules
280.5
Larval Fat Body
2256.4
Larval Salivary Gland
772.3
Larval Trachea
1254.375
Larval Carcass
1197.975
Adult Head
755.7
Adult Eye
2651.75
Adult Brain
84.7
Adult Thoracic-Abdominal Ganglion
106.9
Adult Crop
2725.4
Adult Midgut
172.7
Adult Hindgut
886.3
Adult Malpighian Tubules
168.1
Adult Fat Body
418.1
Adult Salivary Gland
291.2
Adult Heart
305.025
Adult VirginFemale Spermatheca
366.5
Adult InseminatedFemale Spermatheca
396.2
Adult Ovary
244.7
Adult Testis
39.2
Adult Male Accessory Gland
613.9
Adult Carcass
356.2
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
755.7
NA
Eye
2651.75
NA
Brain
84.7
315.325
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
106.9
NA
Crop
2725.4
132.6
Midgut
172.7
638.7
Hindgut
886.3
280.5
Malpighian Tubules
168.1
2256.4
Fat Body
418.1
772.3
Salivary Gland
291.2
NA
Heart
305.025
1254.375
Trachea
NA
NA
VirginFemale Spermatheca
366.5
NA
InseminatedFemale Spermatheca
396.2
NA
Ovary
244.7
NA
Testis
39.2
NA
Male Accessory Gland
613.9
1197.975
Carcass
356.2
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
45
central nervous system, larvae L3
19
central nervous system, pupae P8
11
head, virgin 1-day female
69
head, virgin 4-day female
38
head, virgin 20-day female
42
head, mated 1-day female
41
head, mated 4-day female
28
head, mated 20-day female
34
head, mated 1-day male
66
head, mated 4-day male
51
head, mated 20-day male
56
salivary gland, larvae L3 wandering
13
salivary gland, white prepupae
22
digestive system, larvae L3 wandering
25
digestive system, 1-day adult
18
digestive system, 4-day adult
14
digestive system, 20-day adult
15
fat body, larvae L3 wandering
54
fat body, white prepupae
51
fat body, pupae P8
29
carcass, larvae L3 wandering
108
carcass, 1-day adult
17
carcass, 4-day adult
17
carcass, 20-day adult
25
ovary, virgin 4-day female
21
ovary, mated 4-day female
18
testis, mated 4-day male
6
accessory gland, mated 4-day male
28
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(45)
central nervous system, larvae L3
19
central nervous system, pupae P8
11
head, virgin 1-day female
(69)
head, virgin 4-day female
(38)
head, virgin 20-day female
(42)
head, mated 1-day female
(41)
head, mated 4-day female
(28)
head, mated 20-day female
(34)
head, mated 1-day male
(66)
head, mated 4-day male
(51)
head, mated 20-day male
(56)
salivary gland, larvae L3 wandering
13
salivary gland, white prepupae
22
digestive system, larvae L3 wandering
25
digestive system, 1-day adult
18
digestive system, 4-day adult
14
digestive system, 20-day adult
15
fat body, larvae L3 wandering
(54)
fat body, white prepupae
(51)
fat body, pupae P8
(29)
carcass, larvae L3 wandering
(108)
carcass, 1-day adult
17
carcass, 4-day adult
17
carcass, 20-day adult
25
ovary, virgin 4-day female
21
ovary, mated 4-day female
18
testis, mated 4-day male
6
accessory gland, mated 4-day male
(28)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
45
central nervous system, larvae L3
19
central nervous system, pupae P8
11
head, virgin 1-day female
69
head, virgin 4-day female
38
head, virgin 20-day female
42
head, mated 1-day female
41
head, mated 4-day female
28
head, mated 20-day female
34
head, mated 1-day male
66
head, mated 4-day male
51
head, mated 20-day male
56
salivary gland, larvae L3 wandering
13
salivary gland, white prepupae
22
digestive system, larvae L3 wandering
25
digestive system, 1-day adult
18
digestive system, 4-day adult
14
digestive system, 20-day adult
15
fat body, larvae L3 wandering
54
fat body, white prepupae
51
fat body, pupae P8
29
carcass, larvae L3 wandering
(108)
carcass, 1-day adult
17
carcass, 4-day adult
17
carcass, 20-day adult
25
ovary, virgin 4-day female
21
ovary, mated 4-day female
18
testis, mated 4-day male
6
accessory gland, mated 4-day male
28
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
45
central nervous system, larvae L3
19
central nervous system, pupae P8
11
head, virgin 1-day female
69
head, virgin 4-day female
38
head, virgin 20-day female
42
head, mated 1-day female
41
head, mated 4-day female
28
head, mated 20-day female
34
head, mated 1-day male
66
head, mated 4-day male
51
head, mated 20-day male
56
salivary gland, larvae L3 wandering
13
salivary gland, white prepupae
22
digestive system, larvae L3 wandering
25
digestive system, 1-day adult
18
digestive system, 4-day adult
14
digestive system, 20-day adult
15
fat body, larvae L3 wandering
54
fat body, white prepupae
51
fat body, pupae P8
29
carcass, larvae L3 wandering
108
carcass, 1-day adult
17
carcass, 4-day adult
17
carcass, 20-day adult
25
ovary, virgin 4-day female
21
ovary, mated 4-day female
18
testis, mated 4-day male
6
accessory gland, mated 4-day male
28
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
45
central nervous system, larvae L3
19
central nervous system, pupae P8
11
head, virgin 1-day female
69
head, virgin 4-day female
38
head, virgin 20-day female
42
head, mated 1-day female
41
head, mated 4-day female
28
head, mated 20-day female
34
head, mated 1-day male
66
head, mated 4-day male
51
head, mated 20-day male
56
salivary gland, larvae L3 wandering
13
salivary gland, white prepupae
22
digestive system, larvae L3 wandering
25
digestive system, 1-day adult
18
digestive system, 4-day adult
14
digestive system, 20-day adult
15
fat body, larvae L3 wandering
54
fat body, white prepupae
51
fat body, pupae P8
29
carcass, larvae L3 wandering
108
carcass, 1-day adult
17
carcass, 4-day adult
17
carcass, 20-day adult
25
ovary, virgin 4-day female
21
ovary, mated 4-day female
18
testis, mated 4-day male
6
accessory gland, mated 4-day male
28
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(45)
central nervous system, larvae L3
19
central nervous system, pupae P8
11
head, virgin 1-day female
(69)
head, virgin 4-day female
(38)
head, virgin 20-day female
(42)
head, mated 1-day female
(41)
head, mated 4-day female
28
head, mated 20-day female
(34)
head, mated 1-day male
(66)
head, mated 4-day male
(51)
head, mated 20-day male
(56)
salivary gland, larvae L3 wandering
13
salivary gland, white prepupae
22
digestive system, larvae L3 wandering
25
digestive system, 1-day adult
18
digestive system, 4-day adult
14
digestive system, 20-day adult
15
fat body, larvae L3 wandering
(54)
fat body, white prepupae
(51)
fat body, pupae P8
29
carcass, larvae L3 wandering
(108)
carcass, 1-day adult
17
carcass, 4-day adult
17
carcass, 20-day adult
25
ovary, virgin 4-day female
21
ovary, mated 4-day female
18
testis, mated 4-day male
6
accessory gland, mated 4-day male
28
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
45
central nervous system, larvae L3
19
central nervous system, pupae P8
11
head, virgin 1-day female
69
head, virgin 4-day female
38
head, virgin 20-day female
42
head, mated 1-day female
41
head, mated 4-day female
28
head, mated 20-day female
34
head, mated 1-day male
66
head, mated 4-day male
51
head, mated 20-day male
56
salivary gland, larvae L3 wandering
13
salivary gland, white prepupae
22
digestive system, larvae L3 wandering
25
digestive system, 1-day adult
18
digestive system, 4-day adult
14
digestive system, 20-day adult
15
fat body, larvae L3 wandering
54
fat body, white prepupae
51
fat body, pupae P8
29
carcass, larvae L3 wandering
108
carcass, 1-day adult
17
carcass, 4-day adult
17
carcass, 20-day adult
25
ovary, virgin 4-day female
21
ovary, mated 4-day female
18
testis, mated 4-day male
6
accessory gland, mated 4-day male
28
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
45
central nervous system, larvae L3
19
central nervous system, pupae P8
11
head, virgin 1-day female
69
head, virgin 4-day female
38
head, virgin 20-day female
42
head, mated 1-day female
41
head, mated 4-day female
28
head, mated 20-day female
34
head, mated 1-day male
66
head, mated 4-day male
51
head, mated 20-day male
56
salivary gland, larvae L3 wandering
13
salivary gland, white prepupae
22
digestive system, larvae L3 wandering
25
digestive system, 1-day adult
18
digestive system, 4-day adult
14
digestive system, 20-day adult
15
fat body, larvae L3 wandering
54
fat body, white prepupae
51
fat body, pupae P8
29
carcass, larvae L3 wandering
108
carcass, 1-day adult
17
carcass, 4-day adult
17
carcass, 20-day adult
25
ovary, virgin 4-day female
21
ovary, mated 4-day female
18
testis, mated 4-day male
6
accessory gland, mated 4-day male
28
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
27
embryo 02-04hr
28
embryo 04-06hr
14
embryo 06-08hr
19
embryo 08-10hr
30
embryo 10-12hr
83
embryo 12-14hr
99
embryo 14-16hr
118
embryo 16-18hr
51
embryo 18-20hr
12
embryo 20-22hr
9
embryo 22-24hr
10
larva L1
13
larva L2
75
larva L3 12hr old
37
larva L3 puffstage 1-2
85
larva L3 puffstage 3-6
99
larva L3 puffstage 7-9
115
white prepupae new
106
white prepupae 12hr
61
white prepupae 24hr
58
pupae 2d postWPP
101
pupae 3d postWPP
29
pupae 4d postWPP
35
adult male 01day
48
adult male 05day
37
adult male 30day
32
adult female 01day
31
adult female 05day
32
adult female 30day
34
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(27)
embryo 02-04hr
(28)
embryo 04-06hr
14
embryo 06-08hr
19
embryo 08-10hr
(30)
embryo 10-12hr
(83)
embryo 12-14hr
(99)
embryo 14-16hr
(118)
embryo 16-18hr
(51)
embryo 18-20hr
12
embryo 20-22hr
9
embryo 22-24hr
10
larva L1
13
larva L2
(75)
larva L3 12hr old
(37)
larva L3 puffstage 1-2
(85)
larva L3 puffstage 3-6
(99)
larva L3 puffstage 7-9
(115)
white prepupae new
(106)
white prepupae 12hr
(61)
white prepupae 24hr
(58)
pupae 2d postWPP
(101)
pupae 3d postWPP
(29)
pupae 4d postWPP
(35)
adult male 01day
(48)
adult male 05day
(37)
adult male 30day
(32)
adult female 01day
(31)
adult female 05day
(32)
adult female 30day
(34)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
27
embryo 02-04hr
28
embryo 04-06hr
14
embryo 06-08hr
19
embryo 08-10hr
30
embryo 10-12hr
83
embryo 12-14hr
99
embryo 14-16hr
(118)
embryo 16-18hr
51
embryo 18-20hr
12
embryo 20-22hr
9
embryo 22-24hr
10
larva L1
13
larva L2
75
larva L3 12hr old
37
larva L3 puffstage 1-2
85
larva L3 puffstage 3-6
99
larva L3 puffstage 7-9
(115)
white prepupae new
106
white prepupae 12hr
61
white prepupae 24hr
58
pupae 2d postWPP
101
pupae 3d postWPP
29
pupae 4d postWPP
35
adult male 01day
48
adult male 05day
37
adult male 30day
32
adult female 01day
31
adult female 05day
32
adult female 30day
34
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
27
embryo 02-04hr
28
embryo 04-06hr
14
embryo 06-08hr
19
embryo 08-10hr
30
embryo 10-12hr
83
embryo 12-14hr
99
embryo 14-16hr
118
embryo 16-18hr
51
embryo 18-20hr
12
embryo 20-22hr
9
embryo 22-24hr
10
larva L1
13
larva L2
75
larva L3 12hr old
37
larva L3 puffstage 1-2
85
larva L3 puffstage 3-6
99
larva L3 puffstage 7-9
115
white prepupae new
106
white prepupae 12hr
61
white prepupae 24hr
58
pupae 2d postWPP
101
pupae 3d postWPP
29
pupae 4d postWPP
35
adult male 01day
48
adult male 05day
37
adult male 30day
32
adult female 01day
31
adult female 05day
32
adult female 30day
34
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
27
embryo 02-04hr
28
embryo 04-06hr
14
embryo 06-08hr
19
embryo 08-10hr
30
embryo 10-12hr
83
embryo 12-14hr
99
embryo 14-16hr
118
embryo 16-18hr
51
embryo 18-20hr
12
embryo 20-22hr
9
embryo 22-24hr
10
larva L1
13
larva L2
75
larva L3 12hr old
37
larva L3 puffstage 1-2
85
larva L3 puffstage 3-6
99
larva L3 puffstage 7-9
115
white prepupae new
106
white prepupae 12hr
61
white prepupae 24hr
58
pupae 2d postWPP
101
pupae 3d postWPP
29
pupae 4d postWPP
35
adult male 01day
48
adult male 05day
37
adult male 30day
32
adult female 01day
31
adult female 05day
32
adult female 30day
34
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
27
embryo 02-04hr
28
embryo 04-06hr
14
embryo 06-08hr
19
embryo 08-10hr
30
embryo 10-12hr
(83)
embryo 12-14hr
(99)
embryo 14-16hr
(118)
embryo 16-18hr
(51)
embryo 18-20hr
12
embryo 20-22hr
9
embryo 22-24hr
10
larva L1
13
larva L2
(75)
larva L3 12hr old
(37)
larva L3 puffstage 1-2
(85)
larva L3 puffstage 3-6
(99)
larva L3 puffstage 7-9
(115)
white prepupae new
(106)
white prepupae 12hr
(61)
white prepupae 24hr
(58)
pupae 2d postWPP
(101)
pupae 3d postWPP
29
pupae 4d postWPP
(35)
adult male 01day
(48)
adult male 05day
(37)
adult male 30day
32
adult female 01day
31
adult female 05day
32
adult female 30day
(34)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
27
embryo 02-04hr
28
embryo 04-06hr
14
embryo 06-08hr
19
embryo 08-10hr
30
embryo 10-12hr
83
embryo 12-14hr
99
embryo 14-16hr
118
embryo 16-18hr
51
embryo 18-20hr
12
embryo 20-22hr
9
embryo 22-24hr
10
larva L1
13
larva L2
75
larva L3 12hr old
37
larva L3 puffstage 1-2
85
larva L3 puffstage 3-6
99
larva L3 puffstage 7-9
115
white prepupae new
106
white prepupae 12hr
61
white prepupae 24hr
58
pupae 2d postWPP
101
pupae 3d postWPP
29
pupae 4d postWPP
35
adult male 01day
48
adult male 05day
37
adult male 30day
32
adult female 01day
31
adult female 05day
32
adult female 30day
34
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
27
embryo 02-04hr
28
embryo 04-06hr
14
embryo 06-08hr
19
embryo 08-10hr
30
embryo 10-12hr
83
embryo 12-14hr
99
embryo 14-16hr
118
embryo 16-18hr
51
embryo 18-20hr
12
embryo 20-22hr
9
embryo 22-24hr
10
larva L1
13
larva L2
75
larva L3 12hr old
37
larva L3 puffstage 1-2
85
larva L3 puffstage 3-6
99
larva L3 puffstage 7-9
115
white prepupae new
106
white prepupae 12hr
61
white prepupae 24hr
58
pupae 2d postWPP
101
pupae 3d postWPP
29
pupae 4d postWPP
35
adult male 01day
48
adult male 05day
37
adult male 30day
32
adult female 01day
31
adult female 05day
32
adult female 30day
34
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
76
Schneider line 2 Sg4
40
embryonic 1182-4H
29
embryonic GM2
47
embryonic Kc167
30
embryonic S1
40
embryonic S3
56
leg disc CME L1
36
wing disc CME-W2
51
wing disc ML-DmD8
43
wing disc ML-DmD9
41
wing disc ML-DmD16-c3
26
wing disc ML-DmD21
49
wing disc ML-DmD32
41
haltere disc ML-DmD17-c3
44
eye-antennal disc ML-DmD11
43
antennal disc ML-DmD20-c5
48
mixed discs ML-DmD4-c1
40
CNS ML-DmBG1-c1
43
CNS ML-DmBG2-c2
48
tumorous blood cells mbn2
64
ovary fGS/OSS
5
ovary OSC
20
ovary OSS
14
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(76)
Schneider line 2 Sg4
(40)
embryonic 1182-4H
(29)
embryonic GM2
(47)
embryonic Kc167
(30)
embryonic S1
(40)
embryonic S3
(56)
leg disc CME L1
(36)
wing disc CME-W2
(51)
wing disc ML-DmD8
(43)
wing disc ML-DmD9
(41)
wing disc ML-DmD16-c3
26
wing disc ML-DmD21
(49)
wing disc ML-DmD32
(41)
haltere disc ML-DmD17-c3
(44)
eye-antennal disc ML-DmD11
(43)
antennal disc ML-DmD20-c5
(48)
mixed discs ML-DmD4-c1
(40)
CNS ML-DmBG1-c1
(43)
CNS ML-DmBG2-c2
(48)
tumorous blood cells mbn2
(64)
ovary fGS/OSS
5
ovary OSC
20
ovary OSS
14
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
76
Schneider line 2 Sg4
40
embryonic 1182-4H
29
embryonic GM2
47
embryonic Kc167
30
embryonic S1
40
embryonic S3
56
leg disc CME L1
36
wing disc CME-W2
51
wing disc ML-DmD8
43
wing disc ML-DmD9
41
wing disc ML-DmD16-c3
26
wing disc ML-DmD21
49
wing disc ML-DmD32
41
haltere disc ML-DmD17-c3
44
eye-antennal disc ML-DmD11
43
antennal disc ML-DmD20-c5
48
mixed discs ML-DmD4-c1
40
CNS ML-DmBG1-c1
43
CNS ML-DmBG2-c2
48
tumorous blood cells mbn2
64
ovary fGS/OSS
5
ovary OSC
20
ovary OSS
14
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
76
Schneider line 2 Sg4
40
embryonic 1182-4H
29
embryonic GM2
47
embryonic Kc167
30
embryonic S1
40
embryonic S3
56
leg disc CME L1
36
wing disc CME-W2
51
wing disc ML-DmD8
43
wing disc ML-DmD9
41
wing disc ML-DmD16-c3
26
wing disc ML-DmD21
49
wing disc ML-DmD32
41
haltere disc ML-DmD17-c3
44
eye-antennal disc ML-DmD11
43
antennal disc ML-DmD20-c5
48
mixed discs ML-DmD4-c1
40
CNS ML-DmBG1-c1
43
CNS ML-DmBG2-c2
48
tumorous blood cells mbn2
64
ovary fGS/OSS
5
ovary OSC
20
ovary OSS
14
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
76
Schneider line 2 Sg4
40
embryonic 1182-4H
29
embryonic GM2
47
embryonic Kc167
30
embryonic S1
40
embryonic S3
56
leg disc CME L1
36
wing disc CME-W2
51
wing disc ML-DmD8
43
wing disc ML-DmD9
41
wing disc ML-DmD16-c3
26
wing disc ML-DmD21
49
wing disc ML-DmD32
41
haltere disc ML-DmD17-c3
44
eye-antennal disc ML-DmD11
43
antennal disc ML-DmD20-c5
48
mixed discs ML-DmD4-c1
40
CNS ML-DmBG1-c1
43
CNS ML-DmBG2-c2
48
tumorous blood cells mbn2
64
ovary fGS/OSS
5
ovary OSC
20
ovary OSS
14
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(76)
Schneider line 2 Sg4
(40)
embryonic 1182-4H
29
embryonic GM2
(47)
embryonic Kc167
30
embryonic S1
(40)
embryonic S3
(56)
leg disc CME L1
(36)
wing disc CME-W2
(51)
wing disc ML-DmD8
(43)
wing disc ML-DmD9
(41)
wing disc ML-DmD16-c3
26
wing disc ML-DmD21
(49)
wing disc ML-DmD32
(41)
haltere disc ML-DmD17-c3
(44)
eye-antennal disc ML-DmD11
(43)
antennal disc ML-DmD20-c5
(48)
mixed discs ML-DmD4-c1
(40)
CNS ML-DmBG1-c1
(43)
CNS ML-DmBG2-c2
(48)
tumorous blood cells mbn2
(64)
ovary fGS/OSS
5
ovary OSC
20
ovary OSS
14
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
76
Schneider line 2 Sg4
40
embryonic 1182-4H
29
embryonic GM2
47
embryonic Kc167
30
embryonic S1
40
embryonic S3
56
leg disc CME L1
36
wing disc CME-W2
51
wing disc ML-DmD8
43
wing disc ML-DmD9
41
wing disc ML-DmD16-c3
26
wing disc ML-DmD21
49
wing disc ML-DmD32
41
haltere disc ML-DmD17-c3
44
eye-antennal disc ML-DmD11
43
antennal disc ML-DmD20-c5
48
mixed discs ML-DmD4-c1
40
CNS ML-DmBG1-c1
43
CNS ML-DmBG2-c2
48
tumorous blood cells mbn2
64
ovary fGS/OSS
5
ovary OSC
20
ovary OSS
14
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
76
Schneider line 2 Sg4
40
embryonic 1182-4H
29
embryonic GM2
47
embryonic Kc167
30
embryonic S1
40
embryonic S3
56
leg disc CME L1
36
wing disc CME-W2
51
wing disc ML-DmD8
43
wing disc ML-DmD9
41
wing disc ML-DmD16-c3
26
wing disc ML-DmD21
49
wing disc ML-DmD32
41
haltere disc ML-DmD17-c3
44
eye-antennal disc ML-DmD11
43
antennal disc ML-DmD20-c5
48
mixed discs ML-DmD4-c1
40
CNS ML-DmBG1-c1
43
CNS ML-DmBG2-c2
48
tumorous blood cells mbn2
64
ovary fGS/OSS
5
ovary OSC
20
ovary OSS
14
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
10
cold shock, 4-day adult
10
heat shock, 4-day adult
33
Cadmium 50 mM 6 hrs, larvae L3
60
Cadmium 50 mM 12 hrs, larvae L3
108
Cadmium 50 mM 48 hrs, 4-day adult
40
Cadmium 100 mM 48 hrs, 4-day adult
18
Copper 0.5 mM 12 hrs, larvae L3
26
Copper 15 mM 48 hrs, 4-day adult
12
Zinc 5 mM 12 hrs, larvae L3
20
Zinc 4.5 mM 48 hrs, 4-day adult
10
Ethanol 2.5% 3 hrs, larvae L3
26
Ethanol 5% 3 hrs, larvae L3
60
Ethanol 10% 3 hrs, larvae L3
59
Caffeine 1.5 mg/ml 4 hrs, larvae L3
58
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
17
Caffeine 25 mg/ml 48 hrs, 4-day adult
9
Paraquat 5 mM 48 hrs, 4-day adult
23
Paraquat 10 mM 48 hrs, 4-day adult
28
Rotenone 2 μg 12 hrs, larvae L3
67
Rotenone 8 μg 12 hrs, larvae L3
52
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
10
cold shock, 4-day adult
10
heat shock, 4-day adult
(33)
Cadmium 50 mM 6 hrs, larvae L3
(60)
Cadmium 50 mM 12 hrs, larvae L3
(108)
Cadmium 50 mM 48 hrs, 4-day adult
(40)
Cadmium 100 mM 48 hrs, 4-day adult
18
Copper 0.5 mM 12 hrs, larvae L3
26
Copper 15 mM 48 hrs, 4-day adult
12
Zinc 5 mM 12 hrs, larvae L3
20
Zinc 4.5 mM 48 hrs, 4-day adult
10
Ethanol 2.5% 3 hrs, larvae L3
26
Ethanol 5% 3 hrs, larvae L3
(60)
Ethanol 10% 3 hrs, larvae L3
(59)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(58)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
17
Caffeine 25 mg/ml 48 hrs, 4-day adult
9
Paraquat 5 mM 48 hrs, 4-day adult
23
Paraquat 10 mM 48 hrs, 4-day adult
(28)
Rotenone 2 μg 12 hrs, larvae L3
(67)
Rotenone 8 μg 12 hrs, larvae L3
(52)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
10
cold shock, 4-day adult
10
heat shock, 4-day adult
33
Cadmium 50 mM 6 hrs, larvae L3
60
Cadmium 50 mM 12 hrs, larvae L3
(108)
Cadmium 50 mM 48 hrs, 4-day adult
40
Cadmium 100 mM 48 hrs, 4-day adult
18
Copper 0.5 mM 12 hrs, larvae L3
26
Copper 15 mM 48 hrs, 4-day adult
12
Zinc 5 mM 12 hrs, larvae L3
20
Zinc 4.5 mM 48 hrs, 4-day adult
10
Ethanol 2.5% 3 hrs, larvae L3
26
Ethanol 5% 3 hrs, larvae L3
60
Ethanol 10% 3 hrs, larvae L3
59
Caffeine 1.5 mg/ml 4 hrs, larvae L3
58
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
17
Caffeine 25 mg/ml 48 hrs, 4-day adult
9
Paraquat 5 mM 48 hrs, 4-day adult
23
Paraquat 10 mM 48 hrs, 4-day adult
28
Rotenone 2 μg 12 hrs, larvae L3
67
Rotenone 8 μg 12 hrs, larvae L3
52
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
10
cold shock, 4-day adult
10
heat shock, 4-day adult
33
Cadmium 50 mM 6 hrs, larvae L3
60
Cadmium 50 mM 12 hrs, larvae L3
108
Cadmium 50 mM 48 hrs, 4-day adult
40
Cadmium 100 mM 48 hrs, 4-day adult
18
Copper 0.5 mM 12 hrs, larvae L3
26
Copper 15 mM 48 hrs, 4-day adult
12
Zinc 5 mM 12 hrs, larvae L3
20
Zinc 4.5 mM 48 hrs, 4-day adult
10
Ethanol 2.5% 3 hrs, larvae L3
26
Ethanol 5% 3 hrs, larvae L3
60
Ethanol 10% 3 hrs, larvae L3
59
Caffeine 1.5 mg/ml 4 hrs, larvae L3
58
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
17
Caffeine 25 mg/ml 48 hrs, 4-day adult
9
Paraquat 5 mM 48 hrs, 4-day adult
23
Paraquat 10 mM 48 hrs, 4-day adult
28
Rotenone 2 μg 12 hrs, larvae L3
67
Rotenone 8 μg 12 hrs, larvae L3
52
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
10
cold shock, 4-day adult
10
heat shock, 4-day adult
33
Cadmium 50 mM 6 hrs, larvae L3
60
Cadmium 50 mM 12 hrs, larvae L3
108
Cadmium 50 mM 48 hrs, 4-day adult
40
Cadmium 100 mM 48 hrs, 4-day adult
18
Copper 0.5 mM 12 hrs, larvae L3
26
Copper 15 mM 48 hrs, 4-day adult
12
Zinc 5 mM 12 hrs, larvae L3
20
Zinc 4.5 mM 48 hrs, 4-day adult
10
Ethanol 2.5% 3 hrs, larvae L3
26
Ethanol 5% 3 hrs, larvae L3
60
Ethanol 10% 3 hrs, larvae L3
59
Caffeine 1.5 mg/ml 4 hrs, larvae L3
58
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
17
Caffeine 25 mg/ml 48 hrs, 4-day adult
9
Paraquat 5 mM 48 hrs, 4-day adult
23
Paraquat 10 mM 48 hrs, 4-day adult
28
Rotenone 2 μg 12 hrs, larvae L3
67
Rotenone 8 μg 12 hrs, larvae L3
52
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
10
cold shock, 4-day adult
10
heat shock, 4-day adult
(33)
Cadmium 50 mM 6 hrs, larvae L3
(60)
Cadmium 50 mM 12 hrs, larvae L3
(108)
Cadmium 50 mM 48 hrs, 4-day adult
(40)
Cadmium 100 mM 48 hrs, 4-day adult
18
Copper 0.5 mM 12 hrs, larvae L3
26
Copper 15 mM 48 hrs, 4-day adult
12
Zinc 5 mM 12 hrs, larvae L3
20
Zinc 4.5 mM 48 hrs, 4-day adult
10
Ethanol 2.5% 3 hrs, larvae L3
26
Ethanol 5% 3 hrs, larvae L3
(60)
Ethanol 10% 3 hrs, larvae L3
(59)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(58)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
17
Caffeine 25 mg/ml 48 hrs, 4-day adult
9
Paraquat 5 mM 48 hrs, 4-day adult
23
Paraquat 10 mM 48 hrs, 4-day adult
28
Rotenone 2 μg 12 hrs, larvae L3
(67)
Rotenone 8 μg 12 hrs, larvae L3
(52)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
10
cold shock, 4-day adult
10
heat shock, 4-day adult
33
Cadmium 50 mM 6 hrs, larvae L3
60
Cadmium 50 mM 12 hrs, larvae L3
108
Cadmium 50 mM 48 hrs, 4-day adult
40
Cadmium 100 mM 48 hrs, 4-day adult
18
Copper 0.5 mM 12 hrs, larvae L3
26
Copper 15 mM 48 hrs, 4-day adult
12
Zinc 5 mM 12 hrs, larvae L3
20
Zinc 4.5 mM 48 hrs, 4-day adult
10
Ethanol 2.5% 3 hrs, larvae L3
26
Ethanol 5% 3 hrs, larvae L3
60
Ethanol 10% 3 hrs, larvae L3
59
Caffeine 1.5 mg/ml 4 hrs, larvae L3
58
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
17
Caffeine 25 mg/ml 48 hrs, 4-day adult
9
Paraquat 5 mM 48 hrs, 4-day adult
23
Paraquat 10 mM 48 hrs, 4-day adult
28
Rotenone 2 μg 12 hrs, larvae L3
67
Rotenone 8 μg 12 hrs, larvae L3
52
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
10
cold shock, 4-day adult
10
heat shock, 4-day adult
33
Cadmium 50 mM 6 hrs, larvae L3
60
Cadmium 50 mM 12 hrs, larvae L3
108
Cadmium 50 mM 48 hrs, 4-day adult
40
Cadmium 100 mM 48 hrs, 4-day adult
18
Copper 0.5 mM 12 hrs, larvae L3
26
Copper 15 mM 48 hrs, 4-day adult
12
Zinc 5 mM 12 hrs, larvae L3
20
Zinc 4.5 mM 48 hrs, 4-day adult
10
Ethanol 2.5% 3 hrs, larvae L3
26
Ethanol 5% 3 hrs, larvae L3
60
Ethanol 10% 3 hrs, larvae L3
59
Caffeine 1.5 mg/ml 4 hrs, larvae L3
58
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
17
Caffeine 25 mg/ml 48 hrs, 4-day adult
9
Paraquat 5 mM 48 hrs, 4-day adult
23
Paraquat 10 mM 48 hrs, 4-day adult
28
Rotenone 2 μg 12 hrs, larvae L3
67
Rotenone 8 μg 12 hrs, larvae L3
52
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 3 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 3 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Disrupted in Transgenic Constructs & Insertions
Transgenic Constructs Insertions insertion of mobile activating element
Gene Ontology: Function, Process
& Cellular Component ( 4 unique terms ) Terms Based on
Experimental Evidence ( 2 terms ) Molecular Function ( 0 terms) Biological Process inferred from genetic interaction with
Ssdp inferred from genetic interaction with
Bx Cellular Component ( 0 terms) Terms Based on Predictions or
Assertions ( 2 terms ) Molecular Function Biological Process Cellular Component ( 0 terms) Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
experimental knowledge based
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (138)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG6VDQJJ )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG6V9V0F )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG6CFZ4Z )
Apis mellifera
Western honey bee
Amel\LOC411202
Apis mellifera
Western honey bee
Amel\GB44426
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG013101
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG011235
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG013099
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG001937
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG013097
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG014279
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG013098
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG001593
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH10381
Atta cephalotes
Leafcutter ant
Acep\ACEP10473
Atta cephalotes
Leafcutter ant
Acep\ACEP10477
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO16827
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO16829
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL12981
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL12979
Linepithema humile
Argentine ant
Lhum\LH22219
Linepithema humile
Argentine ant
Lhum\LH22223
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB11143
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB11145
Solenopsis invicta
Red fire ant
Sinv\SINV19446
Acyrthosiphon pisum
Pea aphid
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Tribolium castaneum
Red flour beetle
Tribolium castaneum
Red flour beetle
Tribolium castaneum
Red flour beetle
Tribolium castaneum
Red flour beetle
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG6KH19P )
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa
(EOG67X1GG )
Caenorhabditis elegans
Nematode
Y
Caenorhabditis elegans
Nematode
Y
Caenorhabditis elegans
Nematode
Y
Caenorhabditis elegans
Nematode
Y
Caenorhabditis elegans
Nematode
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Gallus gallus
Domestic chicken
Y
Gallus gallus
Domestic chicken
Y
Gallus gallus
Domestic chicken
Y
Gallus gallus
Domestic chicken
Y
Gallus gallus
Domestic chicken
Y
Gallus gallus
Domestic chicken
Y
Gallus gallus
Domestic chicken
Y
Gallus gallus
Domestic chicken
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Human Orthologs (9)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 5 )Bloomington Harvard VDRC Genomic Clones ( 1 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 47 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for database merge of Additional comments Other Comments External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 2 )Reported As Symbol Synonym CG2767
(
Keleman et al., 2009.8.5 ,
Dierick and Greenspan, 2006 ,
Betz and Darnell, 2006 ,
Juhász et al., 2007 ,
Bronstein et al., 2010 ,
Japanese National Institute of Genetics, 2012.5.21 )
Name Synonym Secondary FlyBase
IDs References ( 23 )Generate a list of List References by type
Recent research papers (0)
All research papers listed in FlyBase were published before 2011
Recent reviews (0)
All reviews listed in FlyBase were published before 2011