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Gene Dmel\Pbp95

General Information
Symbol	Dmel\Pbp95	Species	D. melanogaster
Name	PSEA-binding protein 95kD	Annotation symbol	CG2702
Feature type	protein_coding_gene	FlyBase ID	FBgn0037540
Gene Model Status	Current	Stock availability	3 publicly available
Also Known As	DmSNAP190, DmPBP
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	84E8-84E8	Sequence location	3R:3,839,546..3,842,332 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene PSEA-binding protein 95kD is referred to in FlyBase by the symbol Dmel\Pbp95 (CG2702, FBgn0037540). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: bent DNA binding; protein binding; sequence-specific DNA binding; DNA binding. There is experimental evidence that it is involved in the biological process: lateral inhibition; snRNA transcription from RNA polymerase III promoter; snRNA transcription from RNA polymerase II promoter; protein-DNA complex assembly. 5 alleles are reported. The phenotypes of these alleles are annotated with: chaeta; mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: Homeodomain-like; Homeodomain-related; MYB-like; Myb transcription factor; Myb, DNA-binding; SANT domain, DNA binding; Transcription regulator HTH, Myb-type, DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1626115_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Pbp95. Gene sequence location is 3R:3839546..3842332.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01	Alleles Pbp95[MI03676] References Kim et al., 2010, Mol. Cell. Biol. 30(10): 2411--2423 Bellen, 2011.10.25, set956.xml Sequence features BKN20201 HFA15448 Insertions Mi{MIC}Pbp95[MI03676]
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 84E8-84E8   Limits computationally determined from genome sequence between P{EP}EP3060EP3060 and P{PZ}grn05930
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Pbp95 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Pbp95-RA FBtr0081786  NM_141503   2616   721
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Pbp95-PA   FBpp0081282   84.0   721   9.26     NP_649760   AAF54179
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • SANT domain, DNA binding (IPR001005) Homeodomain-like (IPR009057) Homeodomain-related (IPR012287) Myb, DNA-binding (IPR014778) Myb transcription factor (IPR015495) MYB-like (IPR017877) Transcription regulator HTH, Myb-type, DNA-binding (IPR017930)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA392117   AA392153   AA392507   AA538654   AA802480   AA949938   AE014297 AAF54179   AI946808   AW942473   AX094235   AY061240 AAL28788   CO185899   CO188303   CO306511   CZ484184   CZ484185   EC083779   EC194696   EC205088   EC221762   GH944366   GH945426   GH969351   GH971522   GH972386   GH978420   GH978757   GH981844
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VHX0
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0037540    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0037540 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0037540 expression level Developmental Stage   Expression Level embryo 00-02hr    1485 embryo 02-04hr    1184 embryo 04-06hr    712 embryo 06-08hr    556 embryo 08-10hr    571 embryo 10-12hr    300 embryo 12-14hr    410 embryo 14-16hr    319 embryo 16-18hr    285 embryo 18-20hr    103 embryo 20-22hr    304 embryo 22-24hr    391 larva L1    95 larva L2    110 larva L3 12hr old    82 larva L3 puffstage 1-2    104 larva L3 puffstage 3-6    179 larva L3 puffstage 7-9    238 white prepupae new    245 white prepupae 12hr    304 white prepupae 24hr    333 pupae 2d postWPP    183 pupae 3d postWPP    104 pupae 4d postWPP    70 adult male 01day    104 adult male 05day    122 adult male 30day    92 adult female 01day    296 adult female 05day    733 adult female 30day    723 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1485) embryo 02-04hr  (1184) embryo 04-06hr  (712) embryo 06-08hr  (556) embryo 08-10hr  (571) embryo 10-12hr  (300) embryo 12-14hr  (410) embryo 14-16hr  (319) embryo 16-18hr  (285) embryo 18-20hr  103 embryo 20-22hr  (304) embryo 22-24hr  (391) larva L1    95 larva L2  (110) larva L3 12hr old    82 larva L3 puffstage 1-2  104 larva L3 puffstage 3-6  (179) larva L3 puffstage 7-9  (238) white prepupae new  (245) white prepupae 12hr  (304) white prepupae 24hr  (333) pupae 2d postWPP  (183) pupae 3d postWPP  104 pupae 4d postWPP    70 adult male 01day  104 adult male 05day  (122) adult male 30day    92 adult female 01day  (296) adult female 05day  (733) adult female 30day  (723) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  1485 embryo 02-04hr    1184 embryo 04-06hr    712 embryo 06-08hr    556 embryo 08-10hr    571 embryo 10-12hr    300 embryo 12-14hr    410 embryo 14-16hr    319 embryo 16-18hr    285 embryo 18-20hr    103 embryo 20-22hr    304 embryo 22-24hr    391 larva L1    95 larva L2    110 larva L3 12hr old    82 larva L3 puffstage 1-2    104 larva L3 puffstage 3-6    179 larva L3 puffstage 7-9    238 white prepupae new    245 white prepupae 12hr    304 white prepupae 24hr    333 pupae 2d postWPP    183 pupae 3d postWPP    104 pupae 4d postWPP    70 adult male 01day    104 adult male 05day    122 adult male 30day    92 adult female 01day    296 adult female 05day    733 adult female 30day    723 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1485 embryo 02-04hr    1184 embryo 04-06hr    712 embryo 06-08hr    556 embryo 08-10hr    571 embryo 10-12hr    300 embryo 12-14hr    410 embryo 14-16hr    319 embryo 16-18hr    285 embryo 18-20hr    103 embryo 20-22hr    304 embryo 22-24hr    391 larva L1    95 larva L2    110 larva L3 12hr old    82 larva L3 puffstage 1-2    104 larva L3 puffstage 3-6    179 larva L3 puffstage 7-9    238 white prepupae new    245 white prepupae 12hr    304 white prepupae 24hr    333 pupae 2d postWPP    183 pupae 3d postWPP    104 pupae 4d postWPP    70 adult male 01day    104 adult male 05day    122 adult male 30day    92 adult female 01day    296 adult female 05day    733 adult female 30day    723 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1485 embryo 02-04hr    1184 embryo 04-06hr    712 embryo 06-08hr    556 embryo 08-10hr    571 embryo 10-12hr    300 embryo 12-14hr    410 embryo 14-16hr    319 embryo 16-18hr    285 embryo 18-20hr    103 embryo 20-22hr    304 embryo 22-24hr    391 larva L1    95 larva L2    110 larva L3 12hr old    82 larva L3 puffstage 1-2    104 larva L3 puffstage 3-6    179 larva L3 puffstage 7-9    238 white prepupae new    245 white prepupae 12hr    304 white prepupae 24hr    333 pupae 2d postWPP    183 pupae 3d postWPP    104 pupae 4d postWPP    70 adult male 01day    104 adult male 05day    122 adult male 30day    92 adult female 01day    296 adult female 05day    733 adult female 30day    723 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0037540 expression level Developmental Stage   Expression Level embryo 00-02hr    1485 embryo 02-04hr    1184 embryo 04-06hr    712 embryo 06-08hr    556 embryo 08-10hr    571 embryo 10-12hr    300 embryo 12-14hr    410 embryo 14-16hr    319 embryo 16-18hr    285 embryo 18-20hr    103 embryo 20-22hr    304 embryo 22-24hr    391 larva L1    95 larva L2    110 larva L3 12hr old    82 larva L3 puffstage 1-2    104 larva L3 puffstage 3-6    179 larva L3 puffstage 7-9    238 white prepupae new    245 white prepupae 12hr    304 white prepupae 24hr    333 pupae 2d postWPP    183 pupae 3d postWPP    104 pupae 4d postWPP    70 adult male 01day    104 adult male 05day    122 adult male 30day    92 adult female 01day    296 adult female 05day    733 adult female 30day    723 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1485) embryo 02-04hr  (1184) embryo 04-06hr  (712) embryo 06-08hr  (556) embryo 08-10hr  (571) embryo 10-12hr  (300) embryo 12-14hr  (410) embryo 14-16hr  (319) embryo 16-18hr  (285) embryo 18-20hr  103 embryo 20-22hr  (304) embryo 22-24hr  (391) larva L1    95 larva L2  110 larva L3 12hr old    82 larva L3 puffstage 1-2  104 larva L3 puffstage 3-6  (179) larva L3 puffstage 7-9  (238) white prepupae new  (245) white prepupae 12hr  (304) white prepupae 24hr  (333) pupae 2d postWPP  (183) pupae 3d postWPP  104 pupae 4d postWPP    70 adult male 01day  104 adult male 05day  122 adult male 30day    92 adult female 01day  (296) adult female 05day  (733) adult female 30day  (723) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  1485 embryo 02-04hr    1184 embryo 04-06hr    712 embryo 06-08hr    556 embryo 08-10hr    571 embryo 10-12hr    300 embryo 12-14hr    410 embryo 14-16hr    319 embryo 16-18hr    285 embryo 18-20hr    103 embryo 20-22hr    304 embryo 22-24hr    391 larva L1    95 larva L2    110 larva L3 12hr old    82 larva L3 puffstage 1-2    104 larva L3 puffstage 3-6    179 larva L3 puffstage 7-9    238 white prepupae new    245 white prepupae 12hr    304 white prepupae 24hr    333 pupae 2d postWPP    183 pupae 3d postWPP    104 pupae 4d postWPP    70 adult male 01day    104 adult male 05day    122 adult male 30day    92 adult female 01day    296 adult female 05day    733 adult female 30day    723 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1485 embryo 02-04hr    1184 embryo 04-06hr    712 embryo 06-08hr    556 embryo 08-10hr    571 embryo 10-12hr    300 embryo 12-14hr    410 embryo 14-16hr    319 embryo 16-18hr    285 embryo 18-20hr    103 embryo 20-22hr    304 embryo 22-24hr    391 larva L1    95 larva L2    110 larva L3 12hr old    82 larva L3 puffstage 1-2    104 larva L3 puffstage 3-6    179 larva L3 puffstage 7-9    238 white prepupae new    245 white prepupae 12hr    304 white prepupae 24hr    333 pupae 2d postWPP    183 pupae 3d postWPP    104 pupae 4d postWPP    70 adult male 01day    104 adult male 05day    122 adult male 30day    92 adult female 01day    296 adult female 05day    733 adult female 30day    723 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1485 embryo 02-04hr    1184 embryo 04-06hr    712 embryo 06-08hr    556 embryo 08-10hr    571 embryo 10-12hr    300 embryo 12-14hr    410 embryo 14-16hr    319 embryo 16-18hr    285 embryo 18-20hr    103 embryo 20-22hr    304 embryo 22-24hr    391 larva L1    95 larva L2    110 larva L3 12hr old    82 larva L3 puffstage 1-2    104 larva L3 puffstage 3-6    179 larva L3 puffstage 7-9    238 white prepupae new    245 white prepupae 12hr    304 white prepupae 24hr    333 pupae 2d postWPP    183 pupae 3d postWPP    104 pupae 4d postWPP    70 adult male 01day    104 adult male 05day    122 adult male 30day    92 adult female 01day    296 adult female 05day    733 adult female 30day    723 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0037540    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0037540 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0037540 expression level Tissue   Expression Level Larval Central Nervous System    95.075 Larval Midgut    26.3 Larval Hindgut    42.7 Larval Malpighian Tubules    31.7 Larval Fat Body    23 Larval Salivary Gland    37.2 Larval Trachea    41.125 Larval Carcass    36.65 Adult Head    23.9 Adult Eye    24.7 Adult Brain    48.3 Adult Thoracic-Abdominal Ganglion    61.4 Adult Crop    53.1 Adult Midgut    30 Adult Hindgut    37.9 Adult Malpighian Tubules    29.3 Adult Fat Body    42.2 Adult Salivary Gland    38.9 Adult Heart    21.125 Adult VirginFemale Spermatheca    40.9 Adult InseminatedFemale Spermatheca    49.3 Adult Ovary    173.1 Adult Testis    8.1 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    95.075 Larval Midgut    26.3 Larval Hindgut    42.7 Larval Malpighian Tubules    31.7 Larval Fat Body    23 Larval Salivary Gland    37.2 Larval Trachea    41.125 Larval Carcass    36.65 Adult Head    23.9 Adult Eye    24.7 Adult Brain    48.3 Adult Thoracic-Abdominal Ganglion    61.4 Adult Crop    53.1 Adult Midgut    30 Adult Hindgut    37.9 Adult Malpighian Tubules    29.3 Adult Fat Body    42.2 Adult Salivary Gland    38.9 Adult Heart    21.125 Adult VirginFemale Spermatheca    40.9 Adult InseminatedFemale Spermatheca    49.3 Adult Ovary    173.1 Adult Testis    8.1 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    95.075 Larval Midgut    26.3 Larval Hindgut    42.7 Larval Malpighian Tubules    31.7 Larval Fat Body    23 Larval Salivary Gland    37.2 Larval Trachea    41.125 Larval Carcass    36.65 Adult Head    23.9 Adult Eye    24.7 Adult Brain    48.3 Adult Thoracic-Abdominal Ganglion    61.4 Adult Crop    53.1 Adult Midgut    30 Adult Hindgut    37.9 Adult Malpighian Tubules    29.3 Adult Fat Body    42.2 Adult Salivary Gland    38.9 Adult Heart    21.125 Adult VirginFemale Spermatheca    40.9 Adult InseminatedFemale Spermatheca    49.3 Adult Ovary    173.1 Adult Testis    8.1 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    95.075 Larval Midgut    26.3 Larval Hindgut    42.7 Larval Malpighian Tubules    31.7 Larval Fat Body    23 Larval Salivary Gland    37.2 Larval Trachea    41.125 Larval Carcass    36.65 Adult Head    23.9 Adult Eye    24.7 Adult Brain    48.3 Adult Thoracic-Abdominal Ganglion    61.4 Adult Crop    53.1 Adult Midgut    30 Adult Hindgut    37.9 Adult Malpighian Tubules    29.3 Adult Fat Body    42.2 Adult Salivary Gland    38.9 Adult Heart    21.125 Adult VirginFemale Spermatheca    40.9 Adult InseminatedFemale Spermatheca    49.3 Adult Ovary    173.1 Adult Testis    8.1 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0037540 expression level Tissue   Expression Level Larval Central Nervous System    95.075 Larval Midgut    26.3 Larval Hindgut    42.7 Larval Malpighian Tubules    31.7 Larval Fat Body    23 Larval Salivary Gland    37.2 Larval Trachea    41.125 Larval Carcass    36.65 Adult Head    23.9 Adult Eye    24.7 Adult Brain    48.3 Adult Thoracic-Abdominal Ganglion    61.4 Adult Crop    53.1 Adult Midgut    30 Adult Hindgut    37.9 Adult Malpighian Tubules    29.3 Adult Fat Body    42.2 Adult Salivary Gland    38.9 Adult Heart    21.125 Adult VirginFemale Spermatheca    40.9 Adult InseminatedFemale Spermatheca    49.3 Adult Ovary    173.1 Adult Testis    8.1 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    95.075 Larval Midgut    26.3 Larval Hindgut    42.7 Larval Malpighian Tubules    31.7 Larval Fat Body    23 Larval Salivary Gland    37.2 Larval Trachea    41.125 Larval Carcass    36.65 Adult Head    23.9 Adult Eye    24.7 Adult Brain    48.3 Adult Thoracic-Abdominal Ganglion    61.4 Adult Crop    53.1 Adult Midgut    30 Adult Hindgut    37.9 Adult Malpighian Tubules    29.3 Adult Fat Body    42.2 Adult Salivary Gland    38.9 Adult Heart    21.125 Adult VirginFemale Spermatheca    40.9 Adult InseminatedFemale Spermatheca    49.3 Adult Ovary    173.1 Adult Testis    8.1 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    95.075 Larval Midgut    26.3 Larval Hindgut    42.7 Larval Malpighian Tubules    31.7 Larval Fat Body    23 Larval Salivary Gland    37.2 Larval Trachea    41.125 Larval Carcass    36.65 Adult Head    23.9 Adult Eye    24.7 Adult Brain    48.3 Adult Thoracic-Abdominal Ganglion    61.4 Adult Crop    53.1 Adult Midgut    30 Adult Hindgut    37.9 Adult Malpighian Tubules    29.3 Adult Fat Body    42.2 Adult Salivary Gland    38.9 Adult Heart    21.125 Adult VirginFemale Spermatheca    40.9 Adult InseminatedFemale Spermatheca    49.3 Adult Ovary    173.1 Adult Testis    8.1 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    95.075 Larval Midgut    26.3 Larval Hindgut    42.7 Larval Malpighian Tubules    31.7 Larval Fat Body    23 Larval Salivary Gland    37.2 Larval Trachea    41.125 Larval Carcass    36.65 Adult Head    23.9 Adult Eye    24.7 Adult Brain    48.3 Adult Thoracic-Abdominal Ganglion    61.4 Adult Crop    53.1 Adult Midgut    30 Adult Hindgut    37.9 Adult Malpighian Tubules    29.3 Adult Fat Body    42.2 Adult Salivary Gland    38.9 Adult Heart    21.125 Adult VirginFemale Spermatheca    40.9 Adult InseminatedFemale Spermatheca    49.3 Adult Ovary    173.1 Adult Testis    8.1 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland no informative data Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    23.9   NA  Eye    24.7   NA  Brain    48.3   95.075  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    61.4   NA  Crop    53.1   26.3  Midgut    30   42.7  Hindgut    37.9   31.7  Malpighian Tubules    29.3   23  Fat Body    42.2   37.2  Salivary Gland    38.9   NA  Heart    21.125   41.125  Trachea    NA   NA  VirginFemale Spermatheca    40.9   NA  InseminatedFemale Spermatheca    49.3   NA  Ovary    173.1   NA  Testis    8.1   NA  Male Accessory Gland    no informative data   36.65  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_17
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037540 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG2702-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 Pbp95GD9812 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 Pbp95GD9812 Phenotype manifest in Allele chaeta, with Scer\GAL4pnr-MD237 Pbp95GD9812 mesothoracic tergum, with Scer\GAL4pnr-MD237 Pbp95GD9812
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of Pbp95 Class Mutagen Stocks Known lesion Pbp95f01715 piggyBac transposase 1 -- Pbp95MI03676 0 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Pbp95 Class Mutagen Stocks Known lesion Pbp95GD9812 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes Pbp95MtnA.PL in vitro construct - regulatory fusion 0 Yes Pbp95MtnA.T:SV5\V5,T:Zzzz\His6 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6263 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data miscellaneous insertions Mi{MIC}Pbp95MI03676 NA PBac{WH}Pbp95f01715 NA insertion of mobile activating element P{EPgy2}EY05732 NA
Gene Ontology: Function, Process & Cellular Component ( 10 unique terms )
Terms Based on Experimental Evidence ( 9 terms )
Molecular Function
CV term Evidence References
bent DNA binding inferred from direct assay (Hardin et al., 2000) DNA binding inferred from direct assay (Li et al., 2004, Su et al., 1997) protein binding inferred from physical interaction with Pbp45 (Hung et al., 2009) sequence-specific DNA binding inferred from direct assay (Wang and Stumph, 1998, Hung et al., 2009)
Biological Process
CV term Evidence References
lateral inhibition inferred from mutant phenotype (Mummery-Widmer et al., 2009) protein-DNA complex assembly inferred from direct assay (Li et al., 2004, Wang and Stumph, 1998) snRNA transcription from RNA polymerase III promoter inferred from direct assay (Su et al., 1997, Wang and Stumph, 1998) snRNA transcription from RNA polymerase II promoter inferred from direct assay (Su et al., 1997, Wang and Stumph, 1998)
Cellular Component
CV term Evidence References
snRNA-activating protein complex inferred from direct assay (Lai et al., 2008) inferred from physical interaction with Pbp45 (Hung et al., 2009) inferred from physical interaction with Pbp49 (Hung et al., 2009)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
regulation of transcription, DNA-dependent inferred from electronic annotation with InterPro:IPR012287 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Pbp95 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0037540 DroID - A comprehensive database of gene and protein interactions. • FBgn0037540 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40949
Orthologs
Genome-wide drosophilid orthologs	Dana\GF18154 Dere\GG14352 Dgri\GH17334 Dmoj\GI10259 Dper\GL21479 Dpse\GA15437 Dsec\GM10994 Dsim\GD19964 Dvir\GJ11065 Dwil\GK13472 Dyak\GE24961
Curated drosophilid orthologs	Dpse\GA15437
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL004377-PA Aedes aegypti (mosquito) AGAP001156-PA Anopheles gambiae (mosquito) BGIBMGA010685-PA Bombyx mori (silk worm) ENSBTAP00000000060 Bos taurus (bovine) CBP31174 Caenorhabditis briggsae (nematode) ENSCINP00000026722 Ciona intestinalis (sea squirt) 191441 Hypsipyla robusta (cedar shoot borer) PHUM009618-PA Pediculus humanus (human body louse) 139571 Phytophthora sojae (root rot pathogen) ENSPTRP00000036908 Pan troglodytes (chimpanzee) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB14369 NV22947 LH17473 ISCW003831 FBgn0242055 FBgn0215480 FBgn0198326 FBgn0191447 FBgn0165939 JGI_V11_314719 JGI_V11_314839 JGI_V11_225734 JGI_V11_317576 JGI_V11_242390 JGI_V11_317653 FBgn0075454 FBgn0159072 FBgn0133024 FBgn0124804 FBgn0106612 FBgn0095172 CPIJ008913 BGIBMGA010685 ACYPI007460 GB15491 AGAP001156 AAEL007152 AAEL004377 PHUM431720 GLEAN_04408
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Harvard	- PBac{WH}Pbp95f01715
VDRC	v33557 w1118; P{GD9812}v33557 v33558 w1118; P{GD9812}v33558
Genomic Clones ( 1 )
	BACR07M14 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 20 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD18233
Other clones	DPiM_LD18233
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM05652 LD11030 LD11429 LD12487
Other clones	bs30h06 CK01.13B.B8 EK014240 EK039128 EK251301 LD28511 RP004226402 RP004231085 RP004241686 RP004257058 RP004260176 RP004398720 RP004410499 RP004442535
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0037540 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40949
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Pbp95 CG2702 (Li et al., 2004)
Source for database merge of	Source for merge of: CG2702 anon-WO0118547.359 (FlyBase, 1996-) Source for merge of: CG2702 BEST:LD28511 (Rana, 2004.7.8)
Additional comments	Source for merge of CG2702 anon-WO0118547.359 was sequence comparison (date:051113). (Wang and Stumph, 1998, FlyBase, 1996-)
Other Comments
	Area matching Drosophila EST AA392117. (Davies, 2001.3.15) The Pbp95 product cross-links to positions in the 3' half of the PSEA element found in the promoters of snRNA genes. However, there are significant differences in the cross-linking pattern when PSEAs from a U1 or U6 gene are compared. (Wang and Stumph, 1998)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_141503 RefSeq (Proteins) • NP_649760 DDBJ / EMBL / GenBank • AA392117 AA538654 AA949938 AAF54179 AAL28788 AW942473 AX094235 AY061240 CZ484184 CZ484185 Entrez Gene - A searchable database of RefSeq genes. • 40949 UniProtKB/TrEMBL • Q9VHX0
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • SANT domain, DNA binding (IPR001005) Homeodomain-like (IPR009057) Homeodomain-related (IPR012287) Myb, DNA-binding (IPR014778) Myb transcription factor (IPR015495) MYB-like (IPR017877) Transcription regulator HTH, Myb-type, DNA-binding (IPR017930)
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0037540 DroID - A comprehensive database of gene and protein interactions. • FBgn0037540 DRSC - Results from RNAi screens. • FBgn0037540 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037540 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG2702-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0037540 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40949 InParanoid A subset of ortholog calls from InParanoid. • AAEL004377-PA Aedes aegypti (mosquito) AGAP001156-PA Anopheles gambiae (mosquito) BGIBMGA010685-PA Bombyx mori (silk worm) ENSBTAP00000000060 Bos taurus (bovine) CBP31174 Caenorhabditis briggsae (nematode) ENSCINP00000026722 Ciona intestinalis (sea squirt) 191441 Hypsipyla robusta (cedar shoot borer) PHUM009618-PA Pediculus humanus (human body louse) 139571 Phytophthora sojae (root rot pathogen) ENSPTRP00000036908 Pan troglodytes (chimpanzee) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40949 modMine - Data generated by the modENCODE project. • FBgn0037540 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB14369 NV22947 LH17473 ISCW003831 FBgn0242055 FBgn0215480 FBgn0198326 FBgn0191447 FBgn0165939 JGI_V11_314719 JGI_V11_314839 JGI_V11_225734 JGI_V11_317576 JGI_V11_242390 JGI_V11_317653 FBgn0075454 FBgn0159072 FBgn0133024 FBgn0124804 FBgn0106612 FBgn0095172 CPIJ008913 BGIBMGA010685 ACYPI007460 GB15491 AGAP001156 AAEL007152 AAEL004377 PHUM431720 GLEAN_04408
Synonyms & Secondary IDs ( 11 )
Reported As
Symbol Synonym	anon-WO0118547.359   BEST:LD28511   CG2702 (Li et al., 2004, Kwon et al., 2008) DmPBP (Su et al., 1997, Wang and Stumph, 1998, Hardin et al., 2000) DmPBP95 (Li et al., 2004) DmSNAP190 (Li et al., 2004, Lai et al., 2008, Hung et al., 2009, Kim et al., 2010) DmSNAPc (Kim et al., 2010) Pbp95
Name Synonym	CG2702   Drosophila melanogaster PSE-binding protein 95-kDa subunit (Wang and Stumph, 1998) PSEA-binding protein (Hardin et al., 2000) PSEA-binding protein 95kD
Secondary FlyBase IDs
	FBgn0022383 FBgn0046261 FBgn0062071
References ( 26 )
Generate a list of	All references relating to this gene ( 26 )
List References by type	Research paper  ( 9 ) Supplementary material  ( 2 ) Personal communication to FlyBase  ( 6 ) FlyBase analysis  ( 2 ) Patent  ( 1 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 3 ) Automatic genome annotation  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 1 )
	Kim et al., 2010, Mol. Cell. Biol. 30(10): 2411--2423 Identification of SNAPc subunit domains that interact with specific nucleotide positions in the U1 and U6 gene promoters. [FBrf0214992] Show all research papers ...