Gene Dmel\CR18228

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General Information

Symbol

Dmel\CR18228

Species

D. melanogaster

Name

Annotation symbol

CR18228

Feature type

pseudogene_attribute

FlyBase ID

FBgn0037560

Gene Model Status

Current

Stock availability

4 publicly available

Also Known As

CG18228

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

84F6-84F6

Sequence location

3R:4,086,428..4,087,620 [-]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CR18228 (FBgn0037560). It is a pseudogene_attribute from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed during late larval stages, during early pupal stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1635469_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CR18228. Gene sequence location is 3R:4086428..4087620.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

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Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

84F6-84F6

Limits computationally determined from genome sequence between P{PZ}grn⁰⁵⁹³⁰ and P{PZ}Mcm2^rL074

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CR18228 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.42

Gene model reviewed during 5.49

Pseudogene similar to RpA-70; proximate; partial.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

CR18228-RB

FBtr0300631

992

CR18228-RC

FBtr0310082

943

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Name

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		7.9
Larval Midgut		211.8
Larval Hindgut		151.3
Larval Malpighian Tubules		266.9
Larval Fat Body		29.1
Larval Salivary Gland		80.5
Larval Trachea		260.325
Larval Carcass		94.775
Adult Head		180.8
Adult Eye		214.675
Adult Brain		57.6
Adult Thoracic-Abdominal Ganglion		96.1
Adult Crop		414.7
Adult Midgut		272.8
Adult Hindgut		309.3
Adult Malpighian Tubules		346.6
Adult Fat Body		114.9
Adult Salivary Gland		496
Adult Heart		413.775
Adult VirginFemale Spermatheca		222.1
Adult InseminatedFemale Spermatheca		284.2
Adult Ovary		17.6
Adult Testis		36.6
Adult Male Accessory Gland		479
Adult Carcass		144.9
Expression Level Scale		None Low Moderate High

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		7.9
Larval Midgut		211.8
Larval Hindgut		151.3
Larval Malpighian Tubules		266.9
Larval Fat Body		29.1
Larval Salivary Gland		80.5
Larval Trachea		260.325
Larval Carcass		94.775
Adult Head		180.8
Adult Eye		214.675
Adult Brain		57.6
Adult Thoracic-Abdominal Ganglion		96.1
Adult Crop		414.7
Adult Midgut		272.8
Adult Hindgut		309.3
Adult Malpighian Tubules		346.6
Adult Fat Body		114.9
Adult Salivary Gland		496
Adult Heart		413.775
Adult VirginFemale Spermatheca		222.1
Adult InseminatedFemale Spermatheca		284.2
Adult Ovary		17.6
Adult Testis		36.6
Adult Male Accessory Gland		479
Adult Carcass		144.9
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		7.9
Larval Midgut		211.8
Larval Hindgut		151.3
Larval Malpighian Tubules		266.9
Larval Fat Body		29.1
Larval Salivary Gland		80.5
Larval Trachea		260.325
Larval Carcass		94.775
Adult Head		180.8
Adult Eye		214.675
Adult Brain		57.6
Adult Thoracic-Abdominal Ganglion		96.1
Adult Crop		414.7
Adult Midgut		272.8
Adult Hindgut		309.3
Adult Malpighian Tubules		346.6
Adult Fat Body		114.9
Adult Salivary Gland		496
Adult Heart		413.775
Adult VirginFemale Spermatheca		222.1
Adult InseminatedFemale Spermatheca		284.2
Adult Ovary		17.6
Adult Testis		36.6
Adult Male Accessory Gland		479
Adult Carcass		144.9
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		7.9
Larval Midgut		211.8
Larval Hindgut		151.3
Larval Malpighian Tubules		266.9
Larval Fat Body		29.1
Larval Salivary Gland		80.5
Larval Trachea		260.325
Larval Carcass		94.775
Adult Head		180.8
Adult Eye		214.675
Adult Brain		57.6
Adult Thoracic-Abdominal Ganglion		96.1
Adult Crop		414.7
Adult Midgut		272.8
Adult Hindgut		309.3
Adult Malpighian Tubules		346.6
Adult Fat Body		114.9
Adult Salivary Gland		496
Adult Heart		413.775
Adult VirginFemale Spermatheca		222.1
Adult InseminatedFemale Spermatheca		284.2
Adult Ovary		17.6
Adult Testis		36.6
Adult Male Accessory Gland		479
Adult Carcass		144.9
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		7.9
Larval Midgut		211.8
Larval Hindgut		151.3
Larval Malpighian Tubules		266.9
Larval Fat Body		29.1
Larval Salivary Gland		80.5
Larval Trachea		260.325
Larval Carcass		94.775
Adult Head		180.8
Adult Eye		214.675
Adult Brain		57.6
Adult Thoracic-Abdominal Ganglion		96.1
Adult Crop		414.7
Adult Midgut		272.8
Adult Hindgut		309.3
Adult Malpighian Tubules		346.6
Adult Fat Body		114.9
Adult Salivary Gland		496
Adult Heart		413.775
Adult VirginFemale Spermatheca		222.1
Adult InseminatedFemale Spermatheca		284.2
Adult Ovary		17.6
Adult Testis		36.6
Adult Male Accessory Gland		479
Adult Carcass		144.9
Expression Level Scale		None Low Moderate High

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		7.9
Larval Midgut		211.8
Larval Hindgut		151.3
Larval Malpighian Tubules		266.9
Larval Fat Body		29.1
Larval Salivary Gland		80.5
Larval Trachea		260.325
Larval Carcass		94.775
Adult Head		180.8
Adult Eye		214.675
Adult Brain		57.6
Adult Thoracic-Abdominal Ganglion		96.1
Adult Crop		414.7
Adult Midgut		272.8
Adult Hindgut		309.3
Adult Malpighian Tubules		346.6
Adult Fat Body		114.9
Adult Salivary Gland		496
Adult Heart		413.775
Adult VirginFemale Spermatheca		222.1
Adult InseminatedFemale Spermatheca		284.2
Adult Ovary		17.6
Adult Testis		36.6
Adult Male Accessory Gland		479
Adult Carcass		144.9
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		7.9
Larval Midgut		211.8
Larval Hindgut		151.3
Larval Malpighian Tubules		266.9
Larval Fat Body		29.1
Larval Salivary Gland		80.5
Larval Trachea		260.325
Larval Carcass		94.775
Adult Head		180.8
Adult Eye		214.675
Adult Brain		57.6
Adult Thoracic-Abdominal Ganglion		96.1
Adult Crop		414.7
Adult Midgut		272.8
Adult Hindgut		309.3
Adult Malpighian Tubules		346.6
Adult Fat Body		114.9
Adult Salivary Gland		496
Adult Heart		413.775
Adult VirginFemale Spermatheca		222.1
Adult InseminatedFemale Spermatheca		284.2
Adult Ovary		17.6
Adult Testis		36.6
Adult Male Accessory Gland		479
Adult Carcass		144.9
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		7.9
Larval Midgut		211.8
Larval Hindgut		151.3
Larval Malpighian Tubules		266.9
Larval Fat Body		29.1
Larval Salivary Gland		80.5
Larval Trachea		260.325
Larval Carcass		94.775
Adult Head		180.8
Adult Eye		214.675
Adult Brain		57.6
Adult Thoracic-Abdominal Ganglion		96.1
Adult Crop		414.7
Adult Midgut		272.8
Adult Hindgut		309.3
Adult Malpighian Tubules		346.6
Adult Fat Body		114.9
Adult Salivary Gland		496
Adult Heart		413.775
Adult VirginFemale Spermatheca		222.1
Adult InseminatedFemale Spermatheca		284.2
Adult Ovary		17.6
Adult Testis		36.6
Adult Male Accessory Gland		479
Adult Carcass		144.9
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	180.8
NA	Eye	214.675
NA	Brain	57.6
7.9	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	96.1
NA	Crop	414.7
211.8	Midgut	272.8
151.3	Hindgut	309.3
266.9	Malpighian Tubules	346.6
29.1	Fat Body	114.9
80.5	Salivary Gland	496
NA	Heart	413.775
260.325	Trachea	NA
NA	VirginFemale Spermatheca	222.1
NA	InseminatedFemale Spermatheca	284.2
NA	Ovary	no informative data
NA	Testis	36.6
NA	Male Accessory Gland	479
94.775	Carcass	144.9

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		2
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		6
head, virgin 4-day female		7
head, virgin 20-day female		5
head, mated 1-day female		5
head, mated 4-day female		5
head, mated 20-day female		5
head, mated 1-day male		9
head, mated 4-day male		7
head, mated 20-day male		10
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		23
digestive system, 1-day adult		12
digestive system, 4-day adult		9
digestive system, 20-day adult		9
fat body, larvae L3 wandering		4
fat body, white prepupae		1
fat body, pupae P8		0
carcass, larvae L3 wandering		2
carcass, 1-day adult		4
carcass, 4-day adult		6
carcass, 20-day adult		4
ovary, virgin 4-day female		1
ovary, mated 4-day female		2
testis, mated 4-day male		2
accessory gland, mated 4-day male		10
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		2
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		6
head, virgin 4-day female		7
head, virgin 20-day female		5
head, mated 1-day female		5
head, mated 4-day female		5
head, mated 20-day female		5
head, mated 1-day male		9
head, mated 4-day male		7
head, mated 20-day male		10
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		23
digestive system, 1-day adult		12
digestive system, 4-day adult		9
digestive system, 20-day adult		9
fat body, larvae L3 wandering		4
fat body, white prepupae		1
fat body, pupae P8		0
carcass, larvae L3 wandering		2
carcass, 1-day adult		4
carcass, 4-day adult		6
carcass, 20-day adult		4
ovary, virgin 4-day female		1
ovary, mated 4-day female		2
testis, mated 4-day male		2
accessory gland, mated 4-day male		10
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		2
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		6
head, virgin 4-day female		7
head, virgin 20-day female		5
head, mated 1-day female		5
head, mated 4-day female		5
head, mated 20-day female		5
head, mated 1-day male		9
head, mated 4-day male		7
head, mated 20-day male		10
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		23
digestive system, 1-day adult		12
digestive system, 4-day adult		9
digestive system, 20-day adult		9
fat body, larvae L3 wandering		4
fat body, white prepupae		1
fat body, pupae P8		0
carcass, larvae L3 wandering		2
carcass, 1-day adult		4
carcass, 4-day adult		6
carcass, 20-day adult		4
ovary, virgin 4-day female		1
ovary, mated 4-day female		2
testis, mated 4-day male		2
accessory gland, mated 4-day male		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		2
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		6
head, virgin 4-day female		7
head, virgin 20-day female		5
head, mated 1-day female		5
head, mated 4-day female		5
head, mated 20-day female		5
head, mated 1-day male		9
head, mated 4-day male		7
head, mated 20-day male		10
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		23
digestive system, 1-day adult		12
digestive system, 4-day adult		9
digestive system, 20-day adult		9
fat body, larvae L3 wandering		4
fat body, white prepupae		1
fat body, pupae P8		0
carcass, larvae L3 wandering		2
carcass, 1-day adult		4
carcass, 4-day adult		6
carcass, 20-day adult		4
ovary, virgin 4-day female		1
ovary, mated 4-day female		2
testis, mated 4-day male		2
accessory gland, mated 4-day male		10
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		2
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		6
head, virgin 4-day female		7
head, virgin 20-day female		5
head, mated 1-day female		5
head, mated 4-day female		5
head, mated 20-day female		5
head, mated 1-day male		9
head, mated 4-day male		7
head, mated 20-day male		10
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		23
digestive system, 1-day adult		12
digestive system, 4-day adult		9
digestive system, 20-day adult		9
fat body, larvae L3 wandering		4
fat body, white prepupae		1
fat body, pupae P8		0
carcass, larvae L3 wandering		2
carcass, 1-day adult		4
carcass, 4-day adult		6
carcass, 20-day adult		4
ovary, virgin 4-day female		1
ovary, mated 4-day female		2
testis, mated 4-day male		2
accessory gland, mated 4-day male		10
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		2
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		6
head, virgin 4-day female		7
head, virgin 20-day female		5
head, mated 1-day female		5
head, mated 4-day female		5
head, mated 20-day female		5
head, mated 1-day male		9
head, mated 4-day male		7
head, mated 20-day male		10
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		23
digestive system, 1-day adult		12
digestive system, 4-day adult		9
digestive system, 20-day adult		9
fat body, larvae L3 wandering		4
fat body, white prepupae		1
fat body, pupae P8		0
carcass, larvae L3 wandering		2
carcass, 1-day adult		4
carcass, 4-day adult		6
carcass, 20-day adult		4
ovary, virgin 4-day female		1
ovary, mated 4-day female		2
testis, mated 4-day male		2
accessory gland, mated 4-day male		10
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		2
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		6
head, virgin 4-day female		7
head, virgin 20-day female		5
head, mated 1-day female		5
head, mated 4-day female		5
head, mated 20-day female		5
head, mated 1-day male		9
head, mated 4-day male		7
head, mated 20-day male		10
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		23
digestive system, 1-day adult		12
digestive system, 4-day adult		9
digestive system, 20-day adult		9
fat body, larvae L3 wandering		4
fat body, white prepupae		1
fat body, pupae P8		0
carcass, larvae L3 wandering		2
carcass, 1-day adult		4
carcass, 4-day adult		6
carcass, 20-day adult		4
ovary, virgin 4-day female		1
ovary, mated 4-day female		2
testis, mated 4-day male		2
accessory gland, mated 4-day male		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		2
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		6
head, virgin 4-day female		7
head, virgin 20-day female		5
head, mated 1-day female		5
head, mated 4-day female		5
head, mated 20-day female		5
head, mated 1-day male		9
head, mated 4-day male		7
head, mated 20-day male		10
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		23
digestive system, 1-day adult		12
digestive system, 4-day adult		9
digestive system, 20-day adult		9
fat body, larvae L3 wandering		4
fat body, white prepupae		1
fat body, pupae P8		0
carcass, larvae L3 wandering		2
carcass, 1-day adult		4
carcass, 4-day adult		6
carcass, 20-day adult		4
ovary, virgin 4-day female		1
ovary, mated 4-day female		2
testis, mated 4-day male		2
accessory gland, mated 4-day male		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed during late larval stages, during early pupal stages, in adult male stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		0
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		0
embryo 20-22hr		1
embryo 22-24hr		1
larva L1		1
larva L2		1
larva L3 12hr old		4
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		9
larva L3 puffstage 7-9		12
white prepupae new		10
white prepupae 12hr		7
white prepupae 24hr		3
pupae 2d postWPP		3
pupae 3d postWPP		3
pupae 4d postWPP		4
adult male 01day		11
adult male 05day		8
adult male 30day		5
adult female 01day		3
adult female 05day		4
adult female 30day		2
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		0
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		0
embryo 20-22hr		1
embryo 22-24hr		1
larva L1		1
larva L2		1
larva L3 12hr old		4
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		9
larva L3 puffstage 7-9		12
white prepupae new		10
white prepupae 12hr		7
white prepupae 24hr		3
pupae 2d postWPP		3
pupae 3d postWPP		3
pupae 4d postWPP		4
adult male 01day		11
adult male 05day		8
adult male 30day		5
adult female 01day		3
adult female 05day		4
adult female 30day		2
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		0
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		0
embryo 20-22hr		1
embryo 22-24hr		1
larva L1		1
larva L2		1
larva L3 12hr old		4
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		9
larva L3 puffstage 7-9		12
white prepupae new		10
white prepupae 12hr		7
white prepupae 24hr		3
pupae 2d postWPP		3
pupae 3d postWPP		3
pupae 4d postWPP		4
adult male 01day		11
adult male 05day		8
adult male 30day		5
adult female 01day		3
adult female 05day		4
adult female 30day		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		0
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		0
embryo 20-22hr		1
embryo 22-24hr		1
larva L1		1
larva L2		1
larva L3 12hr old		4
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		9
larva L3 puffstage 7-9		12
white prepupae new		10
white prepupae 12hr		7
white prepupae 24hr		3
pupae 2d postWPP		3
pupae 3d postWPP		3
pupae 4d postWPP		4
adult male 01day		11
adult male 05day		8
adult male 30day		5
adult female 01day		3
adult female 05day		4
adult female 30day		2
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		0
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		0
embryo 20-22hr		1
embryo 22-24hr		1
larva L1		1
larva L2		1
larva L3 12hr old		4
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		9
larva L3 puffstage 7-9		12
white prepupae new		10
white prepupae 12hr		7
white prepupae 24hr		3
pupae 2d postWPP		3
pupae 3d postWPP		3
pupae 4d postWPP		4
adult male 01day		11
adult male 05day		8
adult male 30day		5
adult female 01day		3
adult female 05day		4
adult female 30day		2
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		0
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		0
embryo 20-22hr		1
embryo 22-24hr		1
larva L1		1
larva L2		1
larva L3 12hr old		4
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		9
larva L3 puffstage 7-9		12
white prepupae new		10
white prepupae 12hr		7
white prepupae 24hr		3
pupae 2d postWPP		3
pupae 3d postWPP		3
pupae 4d postWPP		4
adult male 01day		11
adult male 05day		8
adult male 30day		5
adult female 01day		3
adult female 05day		4
adult female 30day		2
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		0
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		0
embryo 20-22hr		1
embryo 22-24hr		1
larva L1		1
larva L2		1
larva L3 12hr old		4
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		9
larva L3 puffstage 7-9		12
white prepupae new		10
white prepupae 12hr		7
white prepupae 24hr		3
pupae 2d postWPP		3
pupae 3d postWPP		3
pupae 4d postWPP		4
adult male 01day		11
adult male 05day		8
adult male 30day		5
adult female 01day		3
adult female 05day		4
adult female 30day		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		0
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		0
embryo 20-22hr		1
embryo 22-24hr		1
larva L1		1
larva L2		1
larva L3 12hr old		4
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		9
larva L3 puffstage 7-9		12
white prepupae new		10
white prepupae 12hr		7
white prepupae 24hr		3
pupae 2d postWPP		3
pupae 3d postWPP		3
pupae 4d postWPP		4
adult male 01day		11
adult male 05day		8
adult male 30day		5
adult female 01day		3
adult female 05day		4
adult female 30day		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		1
Schneider line 2 Sg4		31
embryonic 1182-4H		3
embryonic GM2		70
embryonic Kc167		102
embryonic S1		19
embryonic S3		7
leg disc CME L1		13
wing disc CME-W2		30
wing disc ML-DmD8		1
wing disc ML-DmD9		4
wing disc ML-DmD16-c3		15
wing disc ML-DmD21		0
wing disc ML-DmD32		9
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		19
antennal disc ML-DmD20-c5		47
mixed discs ML-DmD4-c1		1
CNS ML-DmBG1-c1		12
CNS ML-DmBG2-c2		24
tumorous blood cells mbn2		9
ovary fGS/OSS		2
ovary OSC		1
ovary OSS		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		1
Schneider line 2 Sg4		(31)
embryonic 1182-4H		3
embryonic GM2		(70)
embryonic Kc167		(102)
embryonic S1		19
embryonic S3		7
leg disc CME L1		13
wing disc CME-W2		(30)
wing disc ML-DmD8		1
wing disc ML-DmD9		4
wing disc ML-DmD16-c3		15
wing disc ML-DmD21		0
wing disc ML-DmD32		9
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		19
antennal disc ML-DmD20-c5		(47)
mixed discs ML-DmD4-c1		1
CNS ML-DmBG1-c1		12
CNS ML-DmBG2-c2		24
tumorous blood cells mbn2		9
ovary fGS/OSS		2
ovary OSC		1
ovary OSS		1
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		1
Schneider line 2 Sg4		31
embryonic 1182-4H		3
embryonic GM2		70
embryonic Kc167		102
embryonic S1		19
embryonic S3		7
leg disc CME L1		13
wing disc CME-W2		30
wing disc ML-DmD8		1
wing disc ML-DmD9		4
wing disc ML-DmD16-c3		15
wing disc ML-DmD21		0
wing disc ML-DmD32		9
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		19
antennal disc ML-DmD20-c5		47
mixed discs ML-DmD4-c1		1
CNS ML-DmBG1-c1		12
CNS ML-DmBG2-c2		24
tumorous blood cells mbn2		9
ovary fGS/OSS		2
ovary OSC		1
ovary OSS		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		1
Schneider line 2 Sg4		31
embryonic 1182-4H		3
embryonic GM2		70
embryonic Kc167		102
embryonic S1		19
embryonic S3		7
leg disc CME L1		13
wing disc CME-W2		30
wing disc ML-DmD8		1
wing disc ML-DmD9		4
wing disc ML-DmD16-c3		15
wing disc ML-DmD21		0
wing disc ML-DmD32		9
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		19
antennal disc ML-DmD20-c5		47
mixed discs ML-DmD4-c1		1
CNS ML-DmBG1-c1		12
CNS ML-DmBG2-c2		24
tumorous blood cells mbn2		9
ovary fGS/OSS		2
ovary OSC		1
ovary OSS		1
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		1
Schneider line 2 Sg4		31
embryonic 1182-4H		3
embryonic GM2		70
embryonic Kc167		102
embryonic S1		19
embryonic S3		7
leg disc CME L1		13
wing disc CME-W2		30
wing disc ML-DmD8		1
wing disc ML-DmD9		4
wing disc ML-DmD16-c3		15
wing disc ML-DmD21		0
wing disc ML-DmD32		9
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		19
antennal disc ML-DmD20-c5		47
mixed discs ML-DmD4-c1		1
CNS ML-DmBG1-c1		12
CNS ML-DmBG2-c2		24
tumorous blood cells mbn2		9
ovary fGS/OSS		2
ovary OSC		1
ovary OSS		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		1
Schneider line 2 Sg4		31
embryonic 1182-4H		3
embryonic GM2		(70)
embryonic Kc167		(102)
embryonic S1		19
embryonic S3		7
leg disc CME L1		13
wing disc CME-W2		30
wing disc ML-DmD8		1
wing disc ML-DmD9		4
wing disc ML-DmD16-c3		15
wing disc ML-DmD21		0
wing disc ML-DmD32		9
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		19
antennal disc ML-DmD20-c5		(47)
mixed discs ML-DmD4-c1		1
CNS ML-DmBG1-c1		12
CNS ML-DmBG2-c2		24
tumorous blood cells mbn2		9
ovary fGS/OSS		2
ovary OSC		1
ovary OSS		1
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		1
Schneider line 2 Sg4		31
embryonic 1182-4H		3
embryonic GM2		70
embryonic Kc167		102
embryonic S1		19
embryonic S3		7
leg disc CME L1		13
wing disc CME-W2		30
wing disc ML-DmD8		1
wing disc ML-DmD9		4
wing disc ML-DmD16-c3		15
wing disc ML-DmD21		0
wing disc ML-DmD32		9
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		19
antennal disc ML-DmD20-c5		47
mixed discs ML-DmD4-c1		1
CNS ML-DmBG1-c1		12
CNS ML-DmBG2-c2		24
tumorous blood cells mbn2		9
ovary fGS/OSS		2
ovary OSC		1
ovary OSS		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		1
Schneider line 2 Sg4		31
embryonic 1182-4H		3
embryonic GM2		70
embryonic Kc167		102
embryonic S1		19
embryonic S3		7
leg disc CME L1		13
wing disc CME-W2		30
wing disc ML-DmD8		1
wing disc ML-DmD9		4
wing disc ML-DmD16-c3		15
wing disc ML-DmD21		0
wing disc ML-DmD32		9
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		19
antennal disc ML-DmD20-c5		47
mixed discs ML-DmD4-c1		1
CNS ML-DmBG1-c1		12
CNS ML-DmBG2-c2		24
tumorous blood cells mbn2		9
ovary fGS/OSS		2
ovary OSC		1
ovary OSS		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		8
Cadmium 50 mM 6 hrs, larvae L3		5
Cadmium 50 mM 12 hrs, larvae L3		20
Cadmium 50 mM 48 hrs, 4-day adult		8
Cadmium 100 mM 48 hrs, 4-day adult		13
Copper 0.5 mM 12 hrs, larvae L3		15
Copper 15 mM 48 hrs, 4-day adult		8
Zinc 5 mM 12 hrs, larvae L3		8
Zinc 4.5 mM 48 hrs, 4-day adult		8
Ethanol 2.5% 3 hrs, larvae L3		5
Ethanol 5% 3 hrs, larvae L3		13
Ethanol 10% 3 hrs, larvae L3		6
Caffeine 1.5 mg/ml 4 hrs, larvae L3		15
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		9
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		8
Cadmium 50 mM 6 hrs, larvae L3		5
Cadmium 50 mM 12 hrs, larvae L3		20
Cadmium 50 mM 48 hrs, 4-day adult		8
Cadmium 100 mM 48 hrs, 4-day adult		13
Copper 0.5 mM 12 hrs, larvae L3		15
Copper 15 mM 48 hrs, 4-day adult		8
Zinc 5 mM 12 hrs, larvae L3		8
Zinc 4.5 mM 48 hrs, 4-day adult		8
Ethanol 2.5% 3 hrs, larvae L3		5
Ethanol 5% 3 hrs, larvae L3		13
Ethanol 10% 3 hrs, larvae L3		6
Caffeine 1.5 mg/ml 4 hrs, larvae L3		15
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		9
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		8
Cadmium 50 mM 6 hrs, larvae L3		5
Cadmium 50 mM 12 hrs, larvae L3		20
Cadmium 50 mM 48 hrs, 4-day adult		8
Cadmium 100 mM 48 hrs, 4-day adult		13
Copper 0.5 mM 12 hrs, larvae L3		15
Copper 15 mM 48 hrs, 4-day adult		8
Zinc 5 mM 12 hrs, larvae L3		8
Zinc 4.5 mM 48 hrs, 4-day adult		8
Ethanol 2.5% 3 hrs, larvae L3		5
Ethanol 5% 3 hrs, larvae L3		13
Ethanol 10% 3 hrs, larvae L3		6
Caffeine 1.5 mg/ml 4 hrs, larvae L3		15
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		9
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		8
Cadmium 50 mM 6 hrs, larvae L3		5
Cadmium 50 mM 12 hrs, larvae L3		20
Cadmium 50 mM 48 hrs, 4-day adult		8
Cadmium 100 mM 48 hrs, 4-day adult		13
Copper 0.5 mM 12 hrs, larvae L3		15
Copper 15 mM 48 hrs, 4-day adult		8
Zinc 5 mM 12 hrs, larvae L3		8
Zinc 4.5 mM 48 hrs, 4-day adult		8
Ethanol 2.5% 3 hrs, larvae L3		5
Ethanol 5% 3 hrs, larvae L3		13
Ethanol 10% 3 hrs, larvae L3		6
Caffeine 1.5 mg/ml 4 hrs, larvae L3		15
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		9
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		8
Cadmium 50 mM 6 hrs, larvae L3		5
Cadmium 50 mM 12 hrs, larvae L3		20
Cadmium 50 mM 48 hrs, 4-day adult		8
Cadmium 100 mM 48 hrs, 4-day adult		13
Copper 0.5 mM 12 hrs, larvae L3		15
Copper 15 mM 48 hrs, 4-day adult		8
Zinc 5 mM 12 hrs, larvae L3		8
Zinc 4.5 mM 48 hrs, 4-day adult		8
Ethanol 2.5% 3 hrs, larvae L3		5
Ethanol 5% 3 hrs, larvae L3		13
Ethanol 10% 3 hrs, larvae L3		6
Caffeine 1.5 mg/ml 4 hrs, larvae L3		15
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		9
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		8
Cadmium 50 mM 6 hrs, larvae L3		5
Cadmium 50 mM 12 hrs, larvae L3		20
Cadmium 50 mM 48 hrs, 4-day adult		8
Cadmium 100 mM 48 hrs, 4-day adult		13
Copper 0.5 mM 12 hrs, larvae L3		15
Copper 15 mM 48 hrs, 4-day adult		8
Zinc 5 mM 12 hrs, larvae L3		8
Zinc 4.5 mM 48 hrs, 4-day adult		8
Ethanol 2.5% 3 hrs, larvae L3		5
Ethanol 5% 3 hrs, larvae L3		13
Ethanol 10% 3 hrs, larvae L3		6
Caffeine 1.5 mg/ml 4 hrs, larvae L3		15
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		9
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		8
Cadmium 50 mM 6 hrs, larvae L3		5
Cadmium 50 mM 12 hrs, larvae L3		20
Cadmium 50 mM 48 hrs, 4-day adult		8
Cadmium 100 mM 48 hrs, 4-day adult		13
Copper 0.5 mM 12 hrs, larvae L3		15
Copper 15 mM 48 hrs, 4-day adult		8
Zinc 5 mM 12 hrs, larvae L3		8
Zinc 4.5 mM 48 hrs, 4-day adult		8
Ethanol 2.5% 3 hrs, larvae L3		5
Ethanol 5% 3 hrs, larvae L3		13
Ethanol 10% 3 hrs, larvae L3		6
Caffeine 1.5 mg/ml 4 hrs, larvae L3		15
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		9
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		8
Cadmium 50 mM 6 hrs, larvae L3		5
Cadmium 50 mM 12 hrs, larvae L3		20
Cadmium 50 mM 48 hrs, 4-day adult		8
Cadmium 100 mM 48 hrs, 4-day adult		13
Copper 0.5 mM 12 hrs, larvae L3		15
Copper 15 mM 48 hrs, 4-day adult		8
Zinc 5 mM 12 hrs, larvae L3		8
Zinc 4.5 mM 48 hrs, 4-day adult		8
Ethanol 2.5% 3 hrs, larvae L3		5
Ethanol 5% 3 hrs, larvae L3		13
Ethanol 10% 3 hrs, larvae L3		6
Caffeine 1.5 mg/ml 4 hrs, larvae L3		15
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		9
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		11
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

External Data & Images

Linkouts

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG18228-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable

CR18228^d07873

Sterility

Allele

fertile

CR18228^d07873

Phenotype manifest in

Allele

Classical Alleles ( 2 )

For All Classical Alleles Show

Allele of CR18228	Class	Mutagen	Stocks	Known lesion
CR18228^d07873		P-element activity	2	--
CR18228^MI01573			1	--

Alleles Carried on Transgenic Constructs ( 2 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CR18228	Class	Mutagen	Stocks	Known lesion
CR18228^KK105319		in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CR18228^GD9534		in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Disrupted in

Df(3R)Exel6147

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{KK105319}

Insertions

Type of insertions

Name

Expression data

insertion of mobile activating element

P{XP}CR18228^d07873

miscellaneous insertions

Mi{MIC}CR18228^MI01573

Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 0 terms )

Sequence Ontology: Class of Gene

non_protein_coding_gene

(FlyBase Genome Annotators, 2008)

nuclear_gene

pseudogene_attribute

(FlyBase Genome Annotators, 2008)

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CR18228 allele

Gene

References

External Data

Linkouts

BioGRID - A database of protein and genetic interactions

•

1073110

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0037560

Orthologs

OrthoDB Orthologs (0) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

No orthologs identified

Dipteran inclusive ortholog search

No orthologs identified

Insect inclusive ortholog search

No orthologs identified

Arthropod inclusive ortholog search

No orthologs identified

Metazoa inclusive ortholog search

No orthologs identified

Orthologs in Drosophila Species (None identified)

No orthologies identified

Orthologs in non-Drosophila Dipterans (None identified)

No non-Drosophilid orthologies identified

Orthologs in non-Dipteran Insects (None identified)

No non-Dipteran orthologies identified

Orthologs in non-Insect Arthropods (None identified)

No non-Insect Arthropod orthologies identified

Orthologs in non-Arthropod Metazoa (None identified)

No non-Arthropod Metazoa orthologies identified

Human Orthologs (0)

Gene

OMIM

HGNC

AAA Orthologs (5) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Stocks & Reagents

Stocks Listed in FlyBase ( 4 )

Bloomington

19285

w¹¹¹⁸; P{XP}CR18228^d07873

32765

y¹ w^*; Mi{MIC}CR18228^MI01573

v101647

Genomic Clones ( 1 )

BACR45A07

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 3 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

IP08052

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0037560

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

8674096

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Other Comments

CG18228 renamed CR18228 in release 5.13; pseudogene (partial duplication) of adjacent gene, RpA-70.

(FlyBase Genome Annotators, 2008)

External Crossreferences & Linkouts

Sequence Crossreferences

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

40971

Other Crossreferences

Linkouts

BioGRID - A database of protein and genetic interactions

•

1073110

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0037560

DRSC - Results from RNAi screens.

•

FBgn0037560

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG18228-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0037560

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

8674096

modMine - Data generated by the modENCODE project.

•

FBgn0037560

Synonyms & Secondary IDs ( 2 )

Reported As

Symbol Synonym

CG18228

(Quinones-Coello, 2007, Wittkopp et al., 2008, Wittkopp et al., 2004, Keleman et al., 2009.8.5, Wittkopp et al., 2008, Rehwinkel et al., 2004)

CR18228

(FlyBase Genome Annotators, 2008, )

Name Synonym

CG18228

Secondary FlyBase IDs

References ( 16 )

Research paper

Wittkopp et al., 2008, Genetics 178(3): 1831--1835: Independent effects of cis- and trans-regulatory variation on gene expression in Drosophila melanogaster. [FBrf0205112]
Landry et al., 2005, Genetics 171(4): 1813--1822: Compensatory cis-trans evolution and the dysregulation of gene expression in interspecific hybrids of Drosophila. [FBrf0190735]
Rehwinkel et al., 2004, Nat. Struct. Mol. Biol. 11(6): 558--566: Genome-wide analysis of mRNAs regulated by the THO complex in Drosophila melanogaster. [FBrf0179407]
Wittkopp et al., 2004, Nature 430(6995): 85--88: Evolutionary changes in cis and trans gene regulation. [FBrf0179517]
Asha et al., 2003, Genetics 163(1): 203--215: Analysis of ras-induced overproliferation in Drosophila hemocytes. [FBrf0155813]

Supplementary material

Wittkopp et al., 2008, Nat. Genet. 40(3):: Supplementary Information [FBrf0208881]
Dietzl et al., 2007, Nature 448(7150):: Supplementary Table 1. [FBrf0202579]
Quinones-Coello, 2007, Genetics 175(3):: Supplemental Table 1. List of genes associated with protein or enhancer traps. [FBrf0200393]
Giot et al., 2003, Science 302(5651):: Tables S1 to S7. [FBrf0166452]

Personal communication to FlyBase

Bellen, 2010.11.12, Set908.xml: Set908.xml [FBrf0212197]
Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510]
Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file): Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340]
Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase.: Exelixis insertion alleles that are not in FlyBase. [FBrf0179797]
Ryder, 2004.4.26, Exelixis CG deletion data.: Exelixis CG deletion data. [FBrf0184335]
Gene Disruption Project members, 2001-, (Computer file): (Computer file) [FBrf0132177]

FlyBase analysis

FlyBase Genome Annotators, 2008, Changes affecting gene model number or type in release 5.13 of the annotated D.melanogaster genome.: Changes affecting gene model number or type in release 5.13 of the annotated D.melanogaster genome. [FBrf0205930]