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Gene Dmel\CG11671

General Information
Symbol	Dmel\CG11671	Species	D. melanogaster
Name		Annotation symbol	CG11671
Feature type	protein_coding_gene	FlyBase ID	FBgn0037562
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	84F8-84F8	Sequence location	3R:4,113,598..4,114,335 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG11671 (FBgn0037562). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed during late larval stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult midgut. Expression at moderate levels in the following post-embryonic organs or tissues: larval midgut, larval/adult hindgut. Comments on Affy2 ProbeSet: ProbeSet 1632882_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG11671. Gene sequence location is 3R:4113598..4114335.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 84F8-84F8   Limits computationally determined from genome sequence between P{PZ}Mcm2rL074 and P{EP}EP833
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG11671 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.49 GC splice donor site postulated
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG11671-RA FBtr0081829  NM_141521   681   140
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG11671-PA   FBpp0081319   14.9   140   5.77     NP_649778   AAF54210
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF54210   AY118861 AAM50721   BI353486   BP549877   BP549878   EV585763
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VHT9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult midgut. Expression at moderate levels in the following post-embryonic organs or tissues: larval midgut, larval/adult hindgut. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1.275 Larval Midgut    225.3 Larval Hindgut    119.3 Larval Malpighian Tubules    10.4 Larval Fat Body    2.4 Larval Salivary Gland    1.5 Larval Trachea    3.875 Larval Carcass    2.55 Adult Head    5.2 Adult Eye    4.75 Adult Brain    1.5 Adult Thoracic-Abdominal Ganglion    0.9 Adult Crop    1.8 Adult Midgut    2354.7 Adult Hindgut    262.4 Adult Malpighian Tubules    29.9 Adult Fat Body    7.9 Adult Salivary Gland    4 Adult Heart    7 Adult VirginFemale Spermatheca    31.4 Adult InseminatedFemale Spermatheca    18.5 Adult Ovary    0.8 Adult Testis    2.8 Adult Male Accessory Gland    1.3 Adult Carcass    5.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    1.275 Larval Midgut    225.3 Larval Hindgut    119.3 Larval Malpighian Tubules    10.4 Larval Fat Body    2.4 Larval Salivary Gland    1.5 Larval Trachea    3.875 Larval Carcass    2.55 Adult Head    5.2 Adult Eye    4.75 Adult Brain    1.5 Adult Thoracic-Abdominal Ganglion    0.9 Adult Crop    1.8 Adult Midgut  (2354.7) Adult Hindgut    262.4 Adult Malpighian Tubules    29.9 Adult Fat Body    7.9 Adult Salivary Gland    4 Adult Heart    7 Adult VirginFemale Spermatheca    31.4 Adult InseminatedFemale Spermatheca    18.5 Adult Ovary    0.8 Adult Testis    2.8 Adult Male Accessory Gland    1.3 Adult Carcass    5.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    1.275 Larval Midgut    225.3 Larval Hindgut    119.3 Larval Malpighian Tubules    10.4 Larval Fat Body    2.4 Larval Salivary Gland    1.5 Larval Trachea    3.875 Larval Carcass    2.55 Adult Head    5.2 Adult Eye    4.75 Adult Brain    1.5 Adult Thoracic-Abdominal Ganglion    0.9 Adult Crop    1.8 Adult Midgut  (2354.7) Adult Hindgut    262.4 Adult Malpighian Tubules    29.9 Adult Fat Body    7.9 Adult Salivary Gland    4 Adult Heart    7 Adult VirginFemale Spermatheca    31.4 Adult InseminatedFemale Spermatheca    18.5 Adult Ovary    0.8 Adult Testis    2.8 Adult Male Accessory Gland    1.3 Adult Carcass    5.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1.275 Larval Midgut    225.3 Larval Hindgut    119.3 Larval Malpighian Tubules    10.4 Larval Fat Body    2.4 Larval Salivary Gland    1.5 Larval Trachea    3.875 Larval Carcass    2.55 Adult Head    5.2 Adult Eye    4.75 Adult Brain    1.5 Adult Thoracic-Abdominal Ganglion    0.9 Adult Crop    1.8 Adult Midgut    2354.7 Adult Hindgut    262.4 Adult Malpighian Tubules    29.9 Adult Fat Body    7.9 Adult Salivary Gland    4 Adult Heart    7 Adult VirginFemale Spermatheca    31.4 Adult InseminatedFemale Spermatheca    18.5 Adult Ovary    0.8 Adult Testis    2.8 Adult Male Accessory Gland    1.3 Adult Carcass    5.7 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1.275 Larval Midgut    225.3 Larval Hindgut    119.3 Larval Malpighian Tubules    10.4 Larval Fat Body    2.4 Larval Salivary Gland    1.5 Larval Trachea    3.875 Larval Carcass    2.55 Adult Head    5.2 Adult Eye    4.75 Adult Brain    1.5 Adult Thoracic-Abdominal Ganglion    0.9 Adult Crop    1.8 Adult Midgut    2354.7 Adult Hindgut    262.4 Adult Malpighian Tubules    29.9 Adult Fat Body    7.9 Adult Salivary Gland    4 Adult Heart    7 Adult VirginFemale Spermatheca    31.4 Adult InseminatedFemale Spermatheca    18.5 Adult Ovary    0.8 Adult Testis    2.8 Adult Male Accessory Gland    1.3 Adult Carcass    5.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    1.275 Larval Midgut    225.3 Larval Hindgut    119.3 Larval Malpighian Tubules    10.4 Larval Fat Body    2.4 Larval Salivary Gland    1.5 Larval Trachea    3.875 Larval Carcass    2.55 Adult Head    5.2 Adult Eye    4.75 Adult Brain    1.5 Adult Thoracic-Abdominal Ganglion    0.9 Adult Crop    1.8 Adult Midgut  (2354.7) Adult Hindgut    262.4 Adult Malpighian Tubules    29.9 Adult Fat Body    7.9 Adult Salivary Gland    4 Adult Heart    7 Adult VirginFemale Spermatheca    31.4 Adult InseminatedFemale Spermatheca    18.5 Adult Ovary    0.8 Adult Testis    2.8 Adult Male Accessory Gland    1.3 Adult Carcass    5.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    1.275 Larval Midgut    225.3 Larval Hindgut    119.3 Larval Malpighian Tubules    10.4 Larval Fat Body    2.4 Larval Salivary Gland    1.5 Larval Trachea    3.875 Larval Carcass    2.55 Adult Head    5.2 Adult Eye    4.75 Adult Brain    1.5 Adult Thoracic-Abdominal Ganglion    0.9 Adult Crop    1.8 Adult Midgut  (2354.7) Adult Hindgut    262.4 Adult Malpighian Tubules    29.9 Adult Fat Body    7.9 Adult Salivary Gland    4 Adult Heart    7 Adult VirginFemale Spermatheca    31.4 Adult InseminatedFemale Spermatheca    18.5 Adult Ovary    0.8 Adult Testis    2.8 Adult Male Accessory Gland    1.3 Adult Carcass    5.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1.275 Larval Midgut    225.3 Larval Hindgut    119.3 Larval Malpighian Tubules    10.4 Larval Fat Body    2.4 Larval Salivary Gland    1.5 Larval Trachea    3.875 Larval Carcass    2.55 Adult Head    5.2 Adult Eye    4.75 Adult Brain    1.5 Adult Thoracic-Abdominal Ganglion    0.9 Adult Crop    1.8 Adult Midgut    2354.7 Adult Hindgut    262.4 Adult Malpighian Tubules    29.9 Adult Fat Body    7.9 Adult Salivary Gland    4 Adult Heart    7 Adult VirginFemale Spermatheca    31.4 Adult InseminatedFemale Spermatheca    18.5 Adult Ovary    0.8 Adult Testis    2.8 Adult Male Accessory Gland    1.3 Adult Carcass    5.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    5.2   NA  Eye    4.75   NA  Brain    1.5   1.275  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    0.9   NA  Crop    1.8   225.3  Midgut    2354.7   119.3  Hindgut    262.4   no informative data  Malpighian Tubules    no informative data   2.4  Fat Body    7.9   1.5  Salivary Gland    4   NA  Heart    7   3.875  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    0.8   NA  Testis    2.8   NA  Male Accessory Gland    1.3   2.55  Carcass    5.7 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    1 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    21 digestive system, 1-day adult    63 digestive system, 4-day adult    63 digestive system, 20-day adult    108 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    1 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    21 digestive system, 1-day adult  (63) digestive system, 4-day adult  (63) digestive system, 20-day adult  (108) fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    1 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    21 digestive system, 1-day adult    63 digestive system, 4-day adult    63 digestive system, 20-day adult  (108) fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    1 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    21 digestive system, 1-day adult    63 digestive system, 4-day adult    63 digestive system, 20-day adult    108 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    1 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    21 digestive system, 1-day adult    63 digestive system, 4-day adult    63 digestive system, 20-day adult    108 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    1 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    21 digestive system, 1-day adult  (63) digestive system, 4-day adult  (63) digestive system, 20-day adult  (108) fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    1 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    21 digestive system, 1-day adult    63 digestive system, 4-day adult    63 digestive system, 20-day adult  108 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    1 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    21 digestive system, 1-day adult    63 digestive system, 4-day adult    63 digestive system, 20-day adult    108 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed during late larval stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    3 larva L3 12hr old    3 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    2 white prepupae 12hr    2 white prepupae 24hr    0 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    8 adult female 05day    8 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    3 larva L3 12hr old    3 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    2 white prepupae 12hr    2 white prepupae 24hr    0 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    8 adult female 05day    8 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    3 larva L3 12hr old    3 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    2 white prepupae 12hr    2 white prepupae 24hr    0 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    8 adult female 05day    8 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    3 larva L3 12hr old    3 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    2 white prepupae 12hr    2 white prepupae 24hr    0 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    8 adult female 05day    8 adult female 30day    14 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    3 larva L3 12hr old    3 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    2 white prepupae 12hr    2 white prepupae 24hr    0 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    8 adult female 05day    8 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    3 larva L3 12hr old    3 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    2 white prepupae 12hr    2 white prepupae 24hr    0 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    8 adult female 05day    8 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    3 larva L3 12hr old    3 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    2 white prepupae 12hr    2 white prepupae 24hr    0 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    8 adult female 05day    8 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    3 larva L3 12hr old    3 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    2 white prepupae 12hr    2 white prepupae 24hr    0 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    8 adult female 05day    8 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    69 Schneider line 2 Sg4    307 embryonic 1182-4H    2 embryonic GM2    267 embryonic Kc167    9 embryonic S1    72 embryonic S3    1 leg disc CME L1    175 wing disc CME-W2    162 wing disc ML-DmD8    2 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    12 wing disc ML-DmD32    51 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5    40 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    37 CNS ML-DmBG2-c2    159 tumorous blood cells mbn2    143 ovary fGS/OSS    1 ovary OSC    12 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (69) Schneider line 2 Sg4  (307) embryonic 1182-4H    2 embryonic GM2  (267) embryonic Kc167    9 embryonic S1  (72) embryonic S3    1 leg disc CME L1  (175) wing disc CME-W2  (162) wing disc ML-DmD8    2 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    12 wing disc ML-DmD32  (51) haltere disc ML-DmD17-c3  (28) eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5  (40) mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1  (37) CNS ML-DmBG2-c2  (159) tumorous blood cells mbn2  (143) ovary fGS/OSS    1 ovary OSC    12 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    69 Schneider line 2 Sg4  (307) embryonic 1182-4H    2 embryonic GM2  (267) embryonic Kc167    9 embryonic S1    72 embryonic S3    1 leg disc CME L1  (175) wing disc CME-W2  (162) wing disc ML-DmD8    2 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    12 wing disc ML-DmD32    51 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5    40 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    37 CNS ML-DmBG2-c2  (159) tumorous blood cells mbn2  (143) ovary fGS/OSS    1 ovary OSC    12 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    69 Schneider line 2 Sg4    307 embryonic 1182-4H    2 embryonic GM2    267 embryonic Kc167    9 embryonic S1    72 embryonic S3    1 leg disc CME L1    175 wing disc CME-W2    162 wing disc ML-DmD8    2 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    12 wing disc ML-DmD32    51 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5    40 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    37 CNS ML-DmBG2-c2    159 tumorous blood cells mbn2    143 ovary fGS/OSS    1 ovary OSC    12 ovary OSS    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    69 Schneider line 2 Sg4    307 embryonic 1182-4H    2 embryonic GM2    267 embryonic Kc167    9 embryonic S1    72 embryonic S3    1 leg disc CME L1    175 wing disc CME-W2    162 wing disc ML-DmD8    2 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    12 wing disc ML-DmD32    51 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5    40 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    37 CNS ML-DmBG2-c2    159 tumorous blood cells mbn2    143 ovary fGS/OSS    1 ovary OSC    12 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (69) Schneider line 2 Sg4  (307) embryonic 1182-4H    2 embryonic GM2  (267) embryonic Kc167    9 embryonic S1  (72) embryonic S3    1 leg disc CME L1  (175) wing disc CME-W2  (162) wing disc ML-DmD8    2 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    12 wing disc ML-DmD32  (51) haltere disc ML-DmD17-c3  28 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5  (40) mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1  (37) CNS ML-DmBG2-c2  (159) tumorous blood cells mbn2  (143) ovary fGS/OSS    1 ovary OSC    12 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    69 Schneider line 2 Sg4  (307) embryonic 1182-4H    2 embryonic GM2  (267) embryonic Kc167    9 embryonic S1    72 embryonic S3    1 leg disc CME L1  (175) wing disc CME-W2  (162) wing disc ML-DmD8    2 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    12 wing disc ML-DmD32    51 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5    40 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    37 CNS ML-DmBG2-c2  (159) tumorous blood cells mbn2  143 ovary fGS/OSS    1 ovary OSC    12 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    69 Schneider line 2 Sg4    307 embryonic 1182-4H    2 embryonic GM2    267 embryonic Kc167    9 embryonic S1    72 embryonic S3    1 leg disc CME L1    175 wing disc CME-W2    162 wing disc ML-DmD8    2 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    12 wing disc ML-DmD32    51 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5    40 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    37 CNS ML-DmBG2-c2    159 tumorous blood cells mbn2    143 ovary fGS/OSS    1 ovary OSC    12 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    1 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    14 Rotenone 8 μg 12 hrs, larvae L3    15 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    1 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    14 Rotenone 8 μg 12 hrs, larvae L3    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    1 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    14 Rotenone 8 μg 12 hrs, larvae L3    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    1 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    14 Rotenone 8 μg 12 hrs, larvae L3    15 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    1 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    14 Rotenone 8 μg 12 hrs, larvae L3    15 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    1 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    14 Rotenone 8 μg 12 hrs, larvae L3    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    1 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    14 Rotenone 8 μg 12 hrs, larvae L3    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    1 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    14 Rotenone 8 μg 12 hrs, larvae L3    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_16
External Data & Images
Linkouts	BDGP expression data • GM23845 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037562 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11671-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG11671GD4780 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG11671 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG11671 Class Mutagen Stocks Known lesion CG11671GD4780 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG11671KK110267 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG11671NIG.11671R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6147 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4780} NA P{KK110267} NA P{NIG.11671R} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG11671 - 128up anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - CG11107 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - CG11266 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - CG3077 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - CG3224 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - CG3735 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - CG3740 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) CG11671 - CG3817 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - CG5726 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - CG6321 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - CG7194 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - Cbp80 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - Eb1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - Hsc70-1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - Imp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - Ns1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - Pk17E anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - RpL7-like anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - RpLP0 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - Rpt2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - SC35 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - SmD2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - SmD3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - SmG anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - Syp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - U3-55K anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - eIF6 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - flw anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - mRpL44 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - mod anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - shrb anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - spoon anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG11671 - tyf anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG11671 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0037562 DroID - A comprehensive database of gene and protein interactions. • FBgn0037562
Orthologs
OrthoDB Orthologs (20) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6C2HXB Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search EOG6CC2Z4 Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search EOG6K9Q89
Orthologs in Drosophila Species (EOG6C2HXB)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG11671     Drosophila simulans   Dsim\GD18531 Y   Drosophila sechellia   Dsec\GM23716 Y   Drosophila erecta   Dere\GG24365 Y   Drosophila yakuba   Dyak\GE25861 Y   Drosophila ananassae   Dana\GF18336 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA11134 Y   Drosophila persimilis   Dper\GL23423 Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (EOG6CC2Z4)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Acyrthosiphon pisum Pea aphid  Apim\ACYPI008629 Y Tribolium castaneum Red flour beetle  Tcas\TC015934 Y
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (EOG6K9Q89)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_001714gn Y Danio rerio Zebrafish  Drer\ENSDARG00000018532 Y Danio rerio Zebrafish  Drer\zgc:112052 Y Danio rerio Zebrafish  Drer\zgc:101715 Y Danio rerio Zebrafish  Drer\CR352229.2 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000010474 Y Gallus gallus Domestic chicken  Ggal\C19orf12 Y Mus musculus House mouse  Mmus\ENSMUSG00000054676 Y Rattus norvegicus Norway rat  Rnor\LOC690000 Y Homo sapiens Human  Hsap\C19orf12 Y
Human Orthologs (1)
Gene OMIM HGNC Hsap\C19orf12
AAA Orthologs (7) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD18531 Drosophila sechellia Dsec\GM23716 Drosophila erecta Dere\GG24365 Drosophila yakuba Dyak\GE25861 Drosophila ananassae Dana\GF18336 Drosophila pseudoobscura pseudoobscura Dpse\GA11134 Drosophila persimilis Dper\GL23423
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v101929 P{KK110267}VIE-260B v41146 w1118; P{GD4780}v41146
Genomic Clones ( 2 )
	BACR33N15 BACR45A07 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 4 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GM23845
Other clones	DPiM_GM23845
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	Dmel_dig_005546_0666_3748 FGM104A05
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0037562 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40976
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG11671 BcDNA:GM23845 (FlyBase, 1996-)
Additional comments	Source for merge of CG11671 BcDNA:GM23845 was a shared cDNA (date:030728). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_141521 RefSeq (Proteins) • NP_649778 DDBJ / EMBL / GenBank • AAF54210 AAM50721 AY118861 BI353486 Entrez Gene - A searchable database of RefSeq genes. • 40976 UniProtKB/TrEMBL • Q9VHT9
Other Crossreferences
	BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GM23845
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0037562 DroID - A comprehensive database of gene and protein interactions. • FBgn0037562 DRSC - Results from RNAi screens. • FBgn0037562 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037562 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11671-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0037562 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40976 modMine - Data generated by the modENCODE project. • FBgn0037562
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	BcDNA:GM23845   CG11671 (Roxstrom-Lindquist et al., 2004, Keleman et al., 2009.8.5, Otsuna and Ito, 2006, Japanese National Institute of Genetics, 2012.5.21, Nawaz et al., 2012)
Name Synonym
Secondary FlyBase IDs
	FBgn0063189
References ( 15 )
Research paper	Nawaz et al., 2012, PLoS ONE 7(5): e35640 Differential evolutionary wiring of the tyrosine kinase btk. [FBrf0218278] Weber et al., 2012, PLoS ONE 7(4): e34745 Genome-Wide Association Analysis of Oxidative Stress Resistance in Drosophila melanogaster. [FBrf0218073] Otsuna and Ito, 2006, J. Comp. Neurol. 497(6): 928--958 Systematic analysis of the visual projection neurons of Drosophila melanogaster. I. Lobula-specific pathways. [FBrf0193607] Page et al., 2005, EMBO J. 24(24): 4304--4315 Spotted-dick, a zinc-finger protein of Drosophila required for expression of Orc4 and S phase. [FBrf0190363] Roxstrom-Lindquist et al., 2004, EMBO Rep. 5(2): 207--212 Parasite-specific immune response in adult Drosophila melanogaster: a genomic study. [FBrf0167559]
Supplementary material	Guruharsha et al., 2011, Cell 147(3): Table S3. [FBrf0218395] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]