Gene Dmel\CG8116

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General Information

Symbol

Dmel\CG8116

Species

D. melanogaster

Name

Annotation symbol

CG8116

Feature type

protein_coding_gene

FlyBase ID

FBgn0037614

Gene Model Status

Current

Stock availability

4 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

85A8-85A9

Sequence location

3R:4,541,965..4,547,042 [+]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG8116 (FBgn0037614). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Uncharacterised protein family, transmembrane-17. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, larval/adult carcass. Gene sequence location is 3R:4541965..4547042.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

85A8-85A9

Limits computationally determined from genome sequence between P{lacW}l(3)L4740^L4740 and P{EP}D1^EP473

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG8116 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.48

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Shares 3' UTR with downstream gene (paralogous pair).

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG8116-RA

FBtr0081905

NM_141561

1831

136

CG8116-RB

FBtr0300543

NM_001170082

2812

136

CG8116-RC

FBtr0300544

NM_001170083

1826

136

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG8116-PA

FBpp0081388

15.1

136

6.36

NP_649818

AAF54273

CG8116-PB

FBpp0289770

15.1

136

6.36

NP_001163553

ACZ94850

CG8116-PC

FBpp0289771

15.1

136

6.36

NP_001163554

ACZ94851

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Uncharacterised protein family, transmembrane-17 (IPR019184)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q9VHN0

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

(Fisher et al., 2012)

Comment:maternally deposited

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, larval/adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		43
central nervous system, larvae L3		37
central nervous system, pupae P8		57
head, virgin 1-day female		24
head, virgin 4-day female		20
head, virgin 20-day female		10
head, mated 1-day female		37
head, mated 4-day female		25
head, mated 20-day female		11
head, mated 1-day male		35
head, mated 4-day male		34
head, mated 20-day male		29
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		11
digestive system, larvae L3 wandering		13
digestive system, 1-day adult		9
digestive system, 4-day adult		25
digestive system, 20-day adult		14
fat body, larvae L3 wandering		11
fat body, white prepupae		14
fat body, pupae P8		12
carcass, larvae L3 wandering		38
carcass, 1-day adult		23
carcass, 4-day adult		38
carcass, 20-day adult		26
ovary, virgin 4-day female		324
ovary, mated 4-day female		419
testis, mated 4-day male		34
accessory gland, mated 4-day male		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(43)
central nervous system, larvae L3		(37)
central nervous system, pupae P8		(57)
head, virgin 1-day female		24
head, virgin 4-day female		20
head, virgin 20-day female		10
head, mated 1-day female		(37)
head, mated 4-day female		25
head, mated 20-day female		11
head, mated 1-day male		(35)
head, mated 4-day male		(34)
head, mated 20-day male		(29)
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		11
digestive system, larvae L3 wandering		13
digestive system, 1-day adult		9
digestive system, 4-day adult		25
digestive system, 20-day adult		14
fat body, larvae L3 wandering		11
fat body, white prepupae		14
fat body, pupae P8		12
carcass, larvae L3 wandering		(38)
carcass, 1-day adult		23
carcass, 4-day adult		(38)
carcass, 20-day adult		26
ovary, virgin 4-day female		(324)
ovary, mated 4-day female		(419)
testis, mated 4-day male		(34)
accessory gland, mated 4-day male		10
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		43
central nervous system, larvae L3		37
central nervous system, pupae P8		57
head, virgin 1-day female		24
head, virgin 4-day female		20
head, virgin 20-day female		10
head, mated 1-day female		37
head, mated 4-day female		25
head, mated 20-day female		11
head, mated 1-day male		35
head, mated 4-day male		34
head, mated 20-day male		29
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		11
digestive system, larvae L3 wandering		13
digestive system, 1-day adult		9
digestive system, 4-day adult		25
digestive system, 20-day adult		14
fat body, larvae L3 wandering		11
fat body, white prepupae		14
fat body, pupae P8		12
carcass, larvae L3 wandering		38
carcass, 1-day adult		23
carcass, 4-day adult		38
carcass, 20-day adult		26
ovary, virgin 4-day female		(324)
ovary, mated 4-day female		(419)
testis, mated 4-day male		34
accessory gland, mated 4-day male		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		43
central nervous system, larvae L3		37
central nervous system, pupae P8		57
head, virgin 1-day female		24
head, virgin 4-day female		20
head, virgin 20-day female		10
head, mated 1-day female		37
head, mated 4-day female		25
head, mated 20-day female		11
head, mated 1-day male		35
head, mated 4-day male		34
head, mated 20-day male		29
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		11
digestive system, larvae L3 wandering		13
digestive system, 1-day adult		9
digestive system, 4-day adult		25
digestive system, 20-day adult		14
fat body, larvae L3 wandering		11
fat body, white prepupae		14
fat body, pupae P8		12
carcass, larvae L3 wandering		38
carcass, 1-day adult		23
carcass, 4-day adult		38
carcass, 20-day adult		26
ovary, virgin 4-day female		324
ovary, mated 4-day female		419
testis, mated 4-day male		34
accessory gland, mated 4-day male		10
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		43
central nervous system, larvae L3		37
central nervous system, pupae P8		57
head, virgin 1-day female		24
head, virgin 4-day female		20
head, virgin 20-day female		10
head, mated 1-day female		37
head, mated 4-day female		25
head, mated 20-day female		11
head, mated 1-day male		35
head, mated 4-day male		34
head, mated 20-day male		29
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		11
digestive system, larvae L3 wandering		13
digestive system, 1-day adult		9
digestive system, 4-day adult		25
digestive system, 20-day adult		14
fat body, larvae L3 wandering		11
fat body, white prepupae		14
fat body, pupae P8		12
carcass, larvae L3 wandering		38
carcass, 1-day adult		23
carcass, 4-day adult		38
carcass, 20-day adult		26
ovary, virgin 4-day female		324
ovary, mated 4-day female		419
testis, mated 4-day male		34
accessory gland, mated 4-day male		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(43)
central nervous system, larvae L3		(37)
central nervous system, pupae P8		(57)
head, virgin 1-day female		24
head, virgin 4-day female		20
head, virgin 20-day female		10
head, mated 1-day female		(37)
head, mated 4-day female		25
head, mated 20-day female		11
head, mated 1-day male		(35)
head, mated 4-day male		(34)
head, mated 20-day male		29
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		11
digestive system, larvae L3 wandering		13
digestive system, 1-day adult		9
digestive system, 4-day adult		25
digestive system, 20-day adult		14
fat body, larvae L3 wandering		11
fat body, white prepupae		14
fat body, pupae P8		12
carcass, larvae L3 wandering		(38)
carcass, 1-day adult		23
carcass, 4-day adult		(38)
carcass, 20-day adult		26
ovary, virgin 4-day female		(324)
ovary, mated 4-day female		(419)
testis, mated 4-day male		(34)
accessory gland, mated 4-day male		10
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		43
central nervous system, larvae L3		37
central nervous system, pupae P8		57
head, virgin 1-day female		24
head, virgin 4-day female		20
head, virgin 20-day female		10
head, mated 1-day female		37
head, mated 4-day female		25
head, mated 20-day female		11
head, mated 1-day male		35
head, mated 4-day male		34
head, mated 20-day male		29
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		11
digestive system, larvae L3 wandering		13
digestive system, 1-day adult		9
digestive system, 4-day adult		25
digestive system, 20-day adult		14
fat body, larvae L3 wandering		11
fat body, white prepupae		14
fat body, pupae P8		12
carcass, larvae L3 wandering		38
carcass, 1-day adult		23
carcass, 4-day adult		38
carcass, 20-day adult		26
ovary, virgin 4-day female		(324)
ovary, mated 4-day female		(419)
testis, mated 4-day male		34
accessory gland, mated 4-day male		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		43
central nervous system, larvae L3		37
central nervous system, pupae P8		57
head, virgin 1-day female		24
head, virgin 4-day female		20
head, virgin 20-day female		10
head, mated 1-day female		37
head, mated 4-day female		25
head, mated 20-day female		11
head, mated 1-day male		35
head, mated 4-day male		34
head, mated 20-day male		29
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		11
digestive system, larvae L3 wandering		13
digestive system, 1-day adult		9
digestive system, 4-day adult		25
digestive system, 20-day adult		14
fat body, larvae L3 wandering		11
fat body, white prepupae		14
fat body, pupae P8		12
carcass, larvae L3 wandering		38
carcass, 1-day adult		23
carcass, 4-day adult		38
carcass, 20-day adult		26
ovary, virgin 4-day female		324
ovary, mated 4-day female		419
testis, mated 4-day male		34
accessory gland, mated 4-day male		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		175
embryo 02-04hr		178
embryo 04-06hr		61
embryo 06-08hr		46
embryo 08-10hr		67
embryo 10-12hr		53
embryo 12-14hr		58
embryo 14-16hr		68
embryo 16-18hr		59
embryo 18-20hr		27
embryo 20-22hr		62
embryo 22-24hr		67
larva L1		22
larva L2		15
larva L3 12hr old		16
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		12
larva L3 puffstage 7-9		22
white prepupae new		27
white prepupae 12hr		20
white prepupae 24hr		20
pupae 2d postWPP		21
pupae 3d postWPP		21
pupae 4d postWPP		12
adult male 01day		16
adult male 05day		17
adult male 30day		15
adult female 01day		50
adult female 05day		101
adult female 30day		99
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(175)
embryo 02-04hr		(178)
embryo 04-06hr		(61)
embryo 06-08hr		(46)
embryo 08-10hr		(67)
embryo 10-12hr		(53)
embryo 12-14hr		(58)
embryo 14-16hr		(68)
embryo 16-18hr		(59)
embryo 18-20hr		(27)
embryo 20-22hr		(62)
embryo 22-24hr		(67)
larva L1		22
larva L2		15
larva L3 12hr old		16
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		12
larva L3 puffstage 7-9		22
white prepupae new		(27)
white prepupae 12hr		20
white prepupae 24hr		20
pupae 2d postWPP		21
pupae 3d postWPP		21
pupae 4d postWPP		12
adult male 01day		16
adult male 05day		17
adult male 30day		15
adult female 01day		(50)
adult female 05day		(101)
adult female 30day		(99)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		(175)
embryo 02-04hr		(178)
embryo 04-06hr		61
embryo 06-08hr		46
embryo 08-10hr		67
embryo 10-12hr		53
embryo 12-14hr		58
embryo 14-16hr		68
embryo 16-18hr		59
embryo 18-20hr		27
embryo 20-22hr		62
embryo 22-24hr		67
larva L1		22
larva L2		15
larva L3 12hr old		16
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		12
larva L3 puffstage 7-9		22
white prepupae new		27
white prepupae 12hr		20
white prepupae 24hr		20
pupae 2d postWPP		21
pupae 3d postWPP		21
pupae 4d postWPP		12
adult male 01day		16
adult male 05day		17
adult male 30day		15
adult female 01day		50
adult female 05day		101
adult female 30day		99
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		175
embryo 02-04hr		178
embryo 04-06hr		61
embryo 06-08hr		46
embryo 08-10hr		67
embryo 10-12hr		53
embryo 12-14hr		58
embryo 14-16hr		68
embryo 16-18hr		59
embryo 18-20hr		27
embryo 20-22hr		62
embryo 22-24hr		67
larva L1		22
larva L2		15
larva L3 12hr old		16
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		12
larva L3 puffstage 7-9		22
white prepupae new		27
white prepupae 12hr		20
white prepupae 24hr		20
pupae 2d postWPP		21
pupae 3d postWPP		21
pupae 4d postWPP		12
adult male 01day		16
adult male 05day		17
adult male 30day		15
adult female 01day		50
adult female 05day		101
adult female 30day		99
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		175
embryo 02-04hr		178
embryo 04-06hr		61
embryo 06-08hr		46
embryo 08-10hr		67
embryo 10-12hr		53
embryo 12-14hr		58
embryo 14-16hr		68
embryo 16-18hr		59
embryo 18-20hr		27
embryo 20-22hr		62
embryo 22-24hr		67
larva L1		22
larva L2		15
larva L3 12hr old		16
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		12
larva L3 puffstage 7-9		22
white prepupae new		27
white prepupae 12hr		20
white prepupae 24hr		20
pupae 2d postWPP		21
pupae 3d postWPP		21
pupae 4d postWPP		12
adult male 01day		16
adult male 05day		17
adult male 30day		15
adult female 01day		50
adult female 05day		101
adult female 30day		99
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(175)
embryo 02-04hr		(178)
embryo 04-06hr		(61)
embryo 06-08hr		(46)
embryo 08-10hr		(67)
embryo 10-12hr		(53)
embryo 12-14hr		(58)
embryo 14-16hr		(68)
embryo 16-18hr		(59)
embryo 18-20hr		27
embryo 20-22hr		(62)
embryo 22-24hr		(67)
larva L1		22
larva L2		15
larva L3 12hr old		16
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		12
larva L3 puffstage 7-9		22
white prepupae new		27
white prepupae 12hr		20
white prepupae 24hr		20
pupae 2d postWPP		21
pupae 3d postWPP		21
pupae 4d postWPP		12
adult male 01day		16
adult male 05day		17
adult male 30day		15
adult female 01day		(50)
adult female 05day		(101)
adult female 30day		(99)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		(175)
embryo 02-04hr		(178)
embryo 04-06hr		61
embryo 06-08hr		46
embryo 08-10hr		67
embryo 10-12hr		53
embryo 12-14hr		58
embryo 14-16hr		68
embryo 16-18hr		59
embryo 18-20hr		27
embryo 20-22hr		62
embryo 22-24hr		67
larva L1		22
larva L2		15
larva L3 12hr old		16
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		12
larva L3 puffstage 7-9		22
white prepupae new		27
white prepupae 12hr		20
white prepupae 24hr		20
pupae 2d postWPP		21
pupae 3d postWPP		21
pupae 4d postWPP		12
adult male 01day		16
adult male 05day		17
adult male 30day		15
adult female 01day		50
adult female 05day		101
adult female 30day		99
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		175
embryo 02-04hr		178
embryo 04-06hr		61
embryo 06-08hr		46
embryo 08-10hr		67
embryo 10-12hr		53
embryo 12-14hr		58
embryo 14-16hr		68
embryo 16-18hr		59
embryo 18-20hr		27
embryo 20-22hr		62
embryo 22-24hr		67
larva L1		22
larva L2		15
larva L3 12hr old		16
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		12
larva L3 puffstage 7-9		22
white prepupae new		27
white prepupae 12hr		20
white prepupae 24hr		20
pupae 2d postWPP		21
pupae 3d postWPP		21
pupae 4d postWPP		12
adult male 01day		16
adult male 05day		17
adult male 30day		15
adult female 01day		50
adult female 05day		101
adult female 30day		99
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		32
Schneider line 2 Sg4		17
embryonic 1182-4H		24
embryonic GM2		72
embryonic Kc167		114
embryonic S1		30
embryonic S3		33
leg disc CME L1		35
wing disc CME-W2		29
wing disc ML-DmD8		30
wing disc ML-DmD9		29
wing disc ML-DmD16-c3		26
wing disc ML-DmD21		16
wing disc ML-DmD32		42
haltere disc ML-DmD17-c3		16
eye-antennal disc ML-DmD11		41
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		25
CNS ML-DmBG1-c1		53
CNS ML-DmBG2-c2		32
tumorous blood cells mbn2		46
ovary fGS/OSS		22
ovary OSC		31
ovary OSS		12
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(32)
Schneider line 2 Sg4		17
embryonic 1182-4H		24
embryonic GM2		(72)
embryonic Kc167		(114)
embryonic S1		(30)
embryonic S3		(33)
leg disc CME L1		(35)
wing disc CME-W2		(29)
wing disc ML-DmD8		(30)
wing disc ML-DmD9		(29)
wing disc ML-DmD16-c3		26
wing disc ML-DmD21		16
wing disc ML-DmD32		(42)
haltere disc ML-DmD17-c3		16
eye-antennal disc ML-DmD11		(41)
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		25
CNS ML-DmBG1-c1		(53)
CNS ML-DmBG2-c2		(32)
tumorous blood cells mbn2		(46)
ovary fGS/OSS		22
ovary OSC		(31)
ovary OSS		12
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		32
Schneider line 2 Sg4		17
embryonic 1182-4H		24
embryonic GM2		72
embryonic Kc167		(114)
embryonic S1		30
embryonic S3		33
leg disc CME L1		35
wing disc CME-W2		29
wing disc ML-DmD8		30
wing disc ML-DmD9		29
wing disc ML-DmD16-c3		26
wing disc ML-DmD21		16
wing disc ML-DmD32		42
haltere disc ML-DmD17-c3		16
eye-antennal disc ML-DmD11		41
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		25
CNS ML-DmBG1-c1		53
CNS ML-DmBG2-c2		32
tumorous blood cells mbn2		46
ovary fGS/OSS		22
ovary OSC		31
ovary OSS		12
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		32
Schneider line 2 Sg4		17
embryonic 1182-4H		24
embryonic GM2		72
embryonic Kc167		114
embryonic S1		30
embryonic S3		33
leg disc CME L1		35
wing disc CME-W2		29
wing disc ML-DmD8		30
wing disc ML-DmD9		29
wing disc ML-DmD16-c3		26
wing disc ML-DmD21		16
wing disc ML-DmD32		42
haltere disc ML-DmD17-c3		16
eye-antennal disc ML-DmD11		41
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		25
CNS ML-DmBG1-c1		53
CNS ML-DmBG2-c2		32
tumorous blood cells mbn2		46
ovary fGS/OSS		22
ovary OSC		31
ovary OSS		12
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		32
Schneider line 2 Sg4		17
embryonic 1182-4H		24
embryonic GM2		72
embryonic Kc167		114
embryonic S1		30
embryonic S3		33
leg disc CME L1		35
wing disc CME-W2		29
wing disc ML-DmD8		30
wing disc ML-DmD9		29
wing disc ML-DmD16-c3		26
wing disc ML-DmD21		16
wing disc ML-DmD32		42
haltere disc ML-DmD17-c3		16
eye-antennal disc ML-DmD11		41
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		25
CNS ML-DmBG1-c1		53
CNS ML-DmBG2-c2		32
tumorous blood cells mbn2		46
ovary fGS/OSS		22
ovary OSC		31
ovary OSS		12
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		32
Schneider line 2 Sg4		17
embryonic 1182-4H		24
embryonic GM2		(72)
embryonic Kc167		(114)
embryonic S1		30
embryonic S3		(33)
leg disc CME L1		(35)
wing disc CME-W2		29
wing disc ML-DmD8		30
wing disc ML-DmD9		29
wing disc ML-DmD16-c3		26
wing disc ML-DmD21		16
wing disc ML-DmD32		(42)
haltere disc ML-DmD17-c3		16
eye-antennal disc ML-DmD11		(41)
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		25
CNS ML-DmBG1-c1		(53)
CNS ML-DmBG2-c2		32
tumorous blood cells mbn2		(46)
ovary fGS/OSS		22
ovary OSC		31
ovary OSS		12
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		32
Schneider line 2 Sg4		17
embryonic 1182-4H		24
embryonic GM2		72
embryonic Kc167		114
embryonic S1		30
embryonic S3		33
leg disc CME L1		35
wing disc CME-W2		29
wing disc ML-DmD8		30
wing disc ML-DmD9		29
wing disc ML-DmD16-c3		26
wing disc ML-DmD21		16
wing disc ML-DmD32		42
haltere disc ML-DmD17-c3		16
eye-antennal disc ML-DmD11		41
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		25
CNS ML-DmBG1-c1		53
CNS ML-DmBG2-c2		32
tumorous blood cells mbn2		46
ovary fGS/OSS		22
ovary OSC		31
ovary OSS		12
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		32
Schneider line 2 Sg4		17
embryonic 1182-4H		24
embryonic GM2		72
embryonic Kc167		114
embryonic S1		30
embryonic S3		33
leg disc CME L1		35
wing disc CME-W2		29
wing disc ML-DmD8		30
wing disc ML-DmD9		29
wing disc ML-DmD16-c3		26
wing disc ML-DmD21		16
wing disc ML-DmD32		42
haltere disc ML-DmD17-c3		16
eye-antennal disc ML-DmD11		41
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		25
CNS ML-DmBG1-c1		53
CNS ML-DmBG2-c2		32
tumorous blood cells mbn2		46
ovary fGS/OSS		22
ovary OSC		31
ovary OSS		12
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		104
cold shock, 4-day adult		55
heat shock, 4-day adult		99
Cadmium 50 mM 6 hrs, larvae L3		16
Cadmium 50 mM 12 hrs, larvae L3		15
Cadmium 50 mM 48 hrs, 4-day adult		113
Cadmium 100 mM 48 hrs, 4-day adult		238
Copper 0.5 mM 12 hrs, larvae L3		20
Copper 15 mM 48 hrs, 4-day adult		260
Zinc 5 mM 12 hrs, larvae L3		20
Zinc 4.5 mM 48 hrs, 4-day adult		73
Ethanol 2.5% 3 hrs, larvae L3		167
Ethanol 5% 3 hrs, larvae L3		16
Ethanol 10% 3 hrs, larvae L3		17
Caffeine 1.5 mg/ml 4 hrs, larvae L3		16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		241
Caffeine 25 mg/ml 48 hrs, 4-day adult		119
Paraquat 5 mM 48 hrs, 4-day adult		164
Paraquat 10 mM 48 hrs, 4-day adult		114
Rotenone 2 μg 12 hrs, larvae L3		17
Rotenone 8 μg 12 hrs, larvae L3		16
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		(104)
cold shock, 4-day adult		(55)
heat shock, 4-day adult		(99)
Cadmium 50 mM 6 hrs, larvae L3		16
Cadmium 50 mM 12 hrs, larvae L3		15
Cadmium 50 mM 48 hrs, 4-day adult		(113)
Cadmium 100 mM 48 hrs, 4-day adult		(238)
Copper 0.5 mM 12 hrs, larvae L3		20
Copper 15 mM 48 hrs, 4-day adult		(260)
Zinc 5 mM 12 hrs, larvae L3		20
Zinc 4.5 mM 48 hrs, 4-day adult		(73)
Ethanol 2.5% 3 hrs, larvae L3		(167)
Ethanol 5% 3 hrs, larvae L3		16
Ethanol 10% 3 hrs, larvae L3		17
Caffeine 1.5 mg/ml 4 hrs, larvae L3		16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(241)
Caffeine 25 mg/ml 48 hrs, 4-day adult		(119)
Paraquat 5 mM 48 hrs, 4-day adult		(164)
Paraquat 10 mM 48 hrs, 4-day adult		(114)
Rotenone 2 μg 12 hrs, larvae L3		17
Rotenone 8 μg 12 hrs, larvae L3		16
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		104
cold shock, 4-day adult		55
heat shock, 4-day adult		99
Cadmium 50 mM 6 hrs, larvae L3		16
Cadmium 50 mM 12 hrs, larvae L3		15
Cadmium 50 mM 48 hrs, 4-day adult		(113)
Cadmium 100 mM 48 hrs, 4-day adult		(238)
Copper 0.5 mM 12 hrs, larvae L3		20
Copper 15 mM 48 hrs, 4-day adult		(260)
Zinc 5 mM 12 hrs, larvae L3		20
Zinc 4.5 mM 48 hrs, 4-day adult		73
Ethanol 2.5% 3 hrs, larvae L3		(167)
Ethanol 5% 3 hrs, larvae L3		16
Ethanol 10% 3 hrs, larvae L3		17
Caffeine 1.5 mg/ml 4 hrs, larvae L3		16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(241)
Caffeine 25 mg/ml 48 hrs, 4-day adult		(119)
Paraquat 5 mM 48 hrs, 4-day adult		(164)
Paraquat 10 mM 48 hrs, 4-day adult		(114)
Rotenone 2 μg 12 hrs, larvae L3		17
Rotenone 8 μg 12 hrs, larvae L3		16
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		104
cold shock, 4-day adult		55
heat shock, 4-day adult		99
Cadmium 50 mM 6 hrs, larvae L3		16
Cadmium 50 mM 12 hrs, larvae L3		15
Cadmium 50 mM 48 hrs, 4-day adult		113
Cadmium 100 mM 48 hrs, 4-day adult		238
Copper 0.5 mM 12 hrs, larvae L3		20
Copper 15 mM 48 hrs, 4-day adult		260
Zinc 5 mM 12 hrs, larvae L3		20
Zinc 4.5 mM 48 hrs, 4-day adult		73
Ethanol 2.5% 3 hrs, larvae L3		167
Ethanol 5% 3 hrs, larvae L3		16
Ethanol 10% 3 hrs, larvae L3		17
Caffeine 1.5 mg/ml 4 hrs, larvae L3		16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		241
Caffeine 25 mg/ml 48 hrs, 4-day adult		119
Paraquat 5 mM 48 hrs, 4-day adult		164
Paraquat 10 mM 48 hrs, 4-day adult		114
Rotenone 2 μg 12 hrs, larvae L3		17
Rotenone 8 μg 12 hrs, larvae L3		16
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		104
cold shock, 4-day adult		55
heat shock, 4-day adult		99
Cadmium 50 mM 6 hrs, larvae L3		16
Cadmium 50 mM 12 hrs, larvae L3		15
Cadmium 50 mM 48 hrs, 4-day adult		113
Cadmium 100 mM 48 hrs, 4-day adult		238
Copper 0.5 mM 12 hrs, larvae L3		20
Copper 15 mM 48 hrs, 4-day adult		260
Zinc 5 mM 12 hrs, larvae L3		20
Zinc 4.5 mM 48 hrs, 4-day adult		73
Ethanol 2.5% 3 hrs, larvae L3		167
Ethanol 5% 3 hrs, larvae L3		16
Ethanol 10% 3 hrs, larvae L3		17
Caffeine 1.5 mg/ml 4 hrs, larvae L3		16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		241
Caffeine 25 mg/ml 48 hrs, 4-day adult		119
Paraquat 5 mM 48 hrs, 4-day adult		164
Paraquat 10 mM 48 hrs, 4-day adult		114
Rotenone 2 μg 12 hrs, larvae L3		17
Rotenone 8 μg 12 hrs, larvae L3		16
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		(104)
cold shock, 4-day adult		(55)
heat shock, 4-day adult		(99)
Cadmium 50 mM 6 hrs, larvae L3		16
Cadmium 50 mM 12 hrs, larvae L3		15
Cadmium 50 mM 48 hrs, 4-day adult		(113)
Cadmium 100 mM 48 hrs, 4-day adult		(238)
Copper 0.5 mM 12 hrs, larvae L3		20
Copper 15 mM 48 hrs, 4-day adult		(260)
Zinc 5 mM 12 hrs, larvae L3		20
Zinc 4.5 mM 48 hrs, 4-day adult		(73)
Ethanol 2.5% 3 hrs, larvae L3		(167)
Ethanol 5% 3 hrs, larvae L3		16
Ethanol 10% 3 hrs, larvae L3		17
Caffeine 1.5 mg/ml 4 hrs, larvae L3		16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(241)
Caffeine 25 mg/ml 48 hrs, 4-day adult		(119)
Paraquat 5 mM 48 hrs, 4-day adult		(164)
Paraquat 10 mM 48 hrs, 4-day adult		(114)
Rotenone 2 μg 12 hrs, larvae L3		17
Rotenone 8 μg 12 hrs, larvae L3		16
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		104
cold shock, 4-day adult		55
heat shock, 4-day adult		99
Cadmium 50 mM 6 hrs, larvae L3		16
Cadmium 50 mM 12 hrs, larvae L3		15
Cadmium 50 mM 48 hrs, 4-day adult		113
Cadmium 100 mM 48 hrs, 4-day adult		(238)
Copper 0.5 mM 12 hrs, larvae L3		20
Copper 15 mM 48 hrs, 4-day adult		(260)
Zinc 5 mM 12 hrs, larvae L3		20
Zinc 4.5 mM 48 hrs, 4-day adult		73
Ethanol 2.5% 3 hrs, larvae L3		(167)
Ethanol 5% 3 hrs, larvae L3		16
Ethanol 10% 3 hrs, larvae L3		17
Caffeine 1.5 mg/ml 4 hrs, larvae L3		16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(241)
Caffeine 25 mg/ml 48 hrs, 4-day adult		119
Paraquat 5 mM 48 hrs, 4-day adult		(164)
Paraquat 10 mM 48 hrs, 4-day adult		114
Rotenone 2 μg 12 hrs, larvae L3		17
Rotenone 8 μg 12 hrs, larvae L3		16
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		104
cold shock, 4-day adult		55
heat shock, 4-day adult		99
Cadmium 50 mM 6 hrs, larvae L3		16
Cadmium 50 mM 12 hrs, larvae L3		15
Cadmium 50 mM 48 hrs, 4-day adult		113
Cadmium 100 mM 48 hrs, 4-day adult		238
Copper 0.5 mM 12 hrs, larvae L3		20
Copper 15 mM 48 hrs, 4-day adult		260
Zinc 5 mM 12 hrs, larvae L3		20
Zinc 4.5 mM 48 hrs, 4-day adult		73
Ethanol 2.5% 3 hrs, larvae L3		167
Ethanol 5% 3 hrs, larvae L3		16
Ethanol 10% 3 hrs, larvae L3		17
Caffeine 1.5 mg/ml 4 hrs, larvae L3		16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		241
Caffeine 25 mg/ml 48 hrs, 4-day adult		119
Paraquat 5 mM 48 hrs, 4-day adult		164
Paraquat 10 mM 48 hrs, 4-day adult		114
Rotenone 2 μg 12 hrs, larvae L3		17
Rotenone 8 μg 12 hrs, larvae L3		16
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

BDGP expression data

•

LD16427

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0037614

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG8116-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable, with Scer\GAL4^pnr-MD237

CG8116^GD3916

Phenotype manifest in

Allele

Classical Alleles ( 2 )

For All Classical Alleles Show

Allele of CG8116	Class	Mutagen	Stocks	Known lesion
CG8116^KG00606		P-element activity	1	--
CG8116^EP3246		P-element activity	0	--

Alleles Carried on Transgenic Constructs ( 4 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG8116	Mutagen	Stocks	Known lesion
CG8116^GD3916	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG8116^GL01078	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG8116^KK111301	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG8116^NIG.8116R	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Disrupted in

Df(3R)Exel6150

(Ryder, 2004.4.26)

Df(3R)Exel8143

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

P{SUPor-P}CG8116^KG00606

insertion of mobile activating element

P{EP}CG8116^EP3246

Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 0 terms )

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG8116 allele

Gene

References

CG8116^EP3246

pnr

(Pena-Rangel et al., 2002)

External Data

Linkouts

BioGRID - A database of protein and genetic interactions

•

66210

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0037614

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

41035

Orthologs

OrthoDB Orthologs (40) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG615H12

Dipteran inclusive ortholog search

EOG634WGG

Insect inclusive ortholog search

EOG6XSJMJ

Arthropod inclusive ortholog search

EOG651C7B

Metazoa inclusive ortholog search

EOG6X6R5B

Orthologs in Drosophila Species (EOG615H12)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA20835

Drosophila persimilis

Dper\GL12472

Drosophila willistoni

Dwil\GK11810

Drosophila virilis

Dvir\GJ22675

Drosophila mojavensis

Dmoj\GI22390

Drosophila grimshawi

Dgri\GH18572

Orthologs in non-Drosophila Dipterans (EOG634WGG)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL005224

Anopheles gambiae

Malaria mosquito

Agam\AGAP003795

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ006109

Orthologs in non-Dipteran Insects (EOG6XSJMJ)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\GB45726

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG020278

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH11195

Atta cephalotes

Leafcutter ant

Acep\ACEP18252

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO21873

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL18174

Linepithema humile

Argentine ant

Lhum\LH23099

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB24135

Solenopsis invicta

Red fire ant

Sinv\SINV23856

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI001867

Pediculus humanus

Human body louse

Phum\PHUM079910

Tribolium castaneum

Red flour beetle

Tcas\TC011020

Orthologs in non-Insect Arthropods (EOG651C7B)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Ixodes scapularis

Deer tick

Isca\ISCW014288

Orthologs in non-Arthropod Metazoa (EOG6X6R5B)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Caenorhabditis elegans

Nematode

Cele\C30B5.9

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_026708gn

Danio rerio

Zebrafish

Drer\AL645792.1

Xenopus tropicalis

Western clawed frog

Xtro\tmem216

Gallus gallus

Domestic chicken

Ggal\TMEM80

Gallus gallus

Domestic chicken

Ggal\ENSGALG00000022369

Mus musculus

House mouse

Mmus\Tmem216

Mus musculus

House mouse

Mmus\ENSMUSG00000025505

Rattus norvegicus

Norway rat

Rnor\ENSRNOG00000020692

Rattus norvegicus

Norway rat

Rnor\Tmem80

Homo sapiens

Human

Hsap\TMEM80

Homo sapiens

Human

Hsap\ENSG00000187049

Human Orthologs (2)

Gene

OMIM

HGNC

Hsap\TMEM80

Hsap\ENSG00000187049

AAA Orthologs (11) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA20835

Drosophila persimilis

Dper\GL12472

Drosophila willistoni

Dwil\GK11810

Drosophila virilis

Dvir\GJ22675

Drosophila mojavensis

Dmoj\GI22390

Drosophila grimshawi

Dgri\GH18572

Stocks & Reagents

Stocks Listed in FlyBase ( 4 )

Bloomington

36837

y¹ sc^* v¹; P{TRiP.GL01078}attP2

12940

y¹ w^67c23; P{SUPor-P}CG8116^KG00606 ry⁵⁰⁶

VDRC

v104624

P{KK111301}VIE-260B

v45735

w¹¹¹⁸; P{GD3916}v45735

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 47 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0037614

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

41035

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

RefSeq (Proteins)

•

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

41035

UniProtKB/TrEMBL

•

Q9VHN0

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Uncharacterised protein family, transmembrane-17 (IPR019184)

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

•

LD16427

Linkouts

BioGRID - A database of protein and genetic interactions

•

66210

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0037614

DRSC - Results from RNAi screens.

•

FBgn0037614

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0037614

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG8116-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0037614

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

41035

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

41035

modMine - Data generated by the modENCODE project.

•

FBgn0037614

Synonyms & Secondary IDs ( 3 )

Reported As

Symbol Synonym

CG8116

(Ni et al., 2011.7.19, Keleman et al., 2009.8.5, Azad et al., 2012, Japanese National Institute of Genetics, 2012.5.21)

EP(3)3246

(Pena-Rangel et al., 2002)

GH04517

(Pena-Rangel et al., 2002)

Name Synonym

Secondary FlyBase IDs

References ( 15 )

Research paper

Azad et al., 2012, G3 (Bethesda) 2(10): 1169--1178: Identification of Genes Underlying Hypoxia Tolerance in Drosophila by a P-element Screen. [FBrf0219647]
Pena-Rangel et al., 2002, Genetics 160(3): 1035--1050: A misexpression study examining dorsal thorax formation in Drosophila melanogaster. [FBrf0147055]

Supplementary material

Graveley et al., 2011, Nature 471(7339):: Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980]
The modENCODE Consortium, 2010, Science 330(6012):: DataS14: Gene co-expression clusters. [FBrf0213979]
Mummery-Widmer et al., 2009, Nature 458(7241):: Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Giot et al., 2003, Science 302(5651):: Tables S1 to S7. [FBrf0166452]

Personal communication to FlyBase

Ni et al., 2011.7.19, TRiP germline vector pVALIUM21.: TRiP germline vector pVALIUM21. [FBrf0214641]
Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510]
Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
Ryder, 2004.4.26, Exelixis CG deletion data.: Exelixis CG deletion data. [FBrf0184335]
Gene Disruption Project members, 2001-, (Computer file): (Computer file) [FBrf0132177]
BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file): Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]

FlyBase analysis

FlyBase, 1996-, FlyBase inference based on genome sequence analysis.: FlyBase inference based on genome sequence analysis. [FBrf0104946]

Stock list

Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY.: RNAi stocks available from NIG-FLY. [FBrf0218457]

Website

Fisher et al., 2012, BDGP insitu homepage: BDGP insitu homepage [FBrf0219073]