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Gene Dmel\CG11980

General Information
Symbol	Dmel\CG11980	Species	D. melanogaster
Name		Annotation symbol	CG11980
Feature type	protein_coding_gene	FlyBase ID	FBgn0037652
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	85C2-85C2	Sequence location	3R:4,829,740..4,831,053 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG11980 (FBgn0037652). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Metal-dependent protein hydrolase; Thioredoxin-like fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1637597_a_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of CG11980. Gene sequence location is 3R:4829740..4831053.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features HFA14456 BKN20263
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 85C2-85C2   Limits computationally determined from genome sequence between P{lacW}l(3)L4740L4740 and P{EP}D1EP473
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG11980 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG11980-RA FBtr0081964  NM_169251   1179   345 CG11980-RB FBtr0081962  NM_169250   1191   358 CG11980-RC FBtr0081963  NM_141600   1182   359
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG11980-PA   FBpp0081444   39.2   345   6.51     NP_731303   AAF54319 CG11980-PB   FBpp0081442   40.9   358   7.13     NP_731302   AAN13405 CG11980-PC   FBpp0081443   40.9   359   6.95     NP_649857   AAN13404
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Thioredoxin-like fold (IPR012336) Metal-dependent protein hydrolase (IPR003226)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA202487   AA694735   AA696163   AA803708   AA951761   AE014297 AAF54319   AE014297 AAN13404   AE014297 AAN13405   AI455877   AI455944   AI512784   AI516746   AI519768   AX094203   AY128451 AAM75044   BI165801   BI169339   BI169684   BI216940   BI236228   BI351720   BI351926   BI366147   BI372406   BI374671   BI375172   BI486854   BI579898   BT012460   CO280406   CO282301   CO285589   CO300101   CO313167   EC067571   EC084050   EC221978   EC240669   EC243363   EC245429   EC245751   EV592287   GH738874   GH739517   GH739734   GH739923   GH739935   GH741141   GH741452   GH741770   GH742140   GH742196   GH742712   GH743072   GH743314   GH743865   GH744432   GH744612   GH744662   GH745551   GH746328   GH746736   GH746929   GH746975   GH746988   GH747081   GH747424   GH761759   GH761870   GH762049   GH762227   GH762267   GH763013   GH763318   GH763430   GH763939   GH764001   GH764092   GH764379   GH764385   GH764650   GH764816   GH765179   GH765397   GH765416   GH765693   GH766110   GH767751   GH767758   GH767762   GH768082   GH768525   GH768544   GH768576   GH768693   GH768737   GH779182   GH779217   GH779867
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8INP8 Q8INP9 Q8MQQ5 Q9VHI8
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0037652    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0037652 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0037652 expression level Developmental Stage   Expression Level embryo 00-02hr    6873 embryo 02-04hr    7878 embryo 04-06hr    5458 embryo 06-08hr    4558 embryo 08-10hr    5275 embryo 10-12hr    4653 embryo 12-14hr    5213 embryo 14-16hr    2797 embryo 16-18hr    2836 embryo 18-20hr    2082 embryo 20-22hr    2743 embryo 22-24hr    3065 larva L1    5341 larva L2    5393 larva L3 12hr old    3553 larva L3 puffstage 1-2    1969 larva L3 puffstage 3-6    2312 larva L3 puffstage 7-9    3100 white prepupae new    2728 white prepupae 12hr    2012 white prepupae 24hr    1898 pupae 2d postWPP    2566 pupae 3d postWPP    1990 pupae 4d postWPP    1095 adult male 01day    1321 adult male 05day    1215 adult male 30day    1112 adult female 01day    3191 adult female 05day    6558 adult female 30day    6526 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (6873) embryo 02-04hr  (7878) embryo 04-06hr  (5458) embryo 06-08hr  (4558) embryo 08-10hr  (5275) embryo 10-12hr  (4653) embryo 12-14hr  (5213) embryo 14-16hr  (2797) embryo 16-18hr  (2836) embryo 18-20hr  (2082) embryo 20-22hr  (2743) embryo 22-24hr  (3065) larva L1  (5341) larva L2  (5393) larva L3 12hr old  (3553) larva L3 puffstage 1-2  (1969) larva L3 puffstage 3-6  (2312) larva L3 puffstage 7-9  (3100) white prepupae new  (2728) white prepupae 12hr  (2012) white prepupae 24hr  (1898) pupae 2d postWPP  (2566) pupae 3d postWPP  (1990) pupae 4d postWPP  (1095) adult male 01day  (1321) adult male 05day  (1215) adult male 30day  (1112) adult female 01day  (3191) adult female 05day  (6558) adult female 30day  (6526) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (6873) embryo 02-04hr  (7878) embryo 04-06hr  (5458) embryo 06-08hr  (4558) embryo 08-10hr  (5275) embryo 10-12hr  (4653) embryo 12-14hr  (5213) embryo 14-16hr  (2797) embryo 16-18hr  (2836) embryo 18-20hr  (2082) embryo 20-22hr  (2743) embryo 22-24hr  (3065) larva L1  (5341) larva L2  (5393) larva L3 12hr old  (3553) larva L3 puffstage 1-2  (1969) larva L3 puffstage 3-6  (2312) larva L3 puffstage 7-9  (3100) white prepupae new  (2728) white prepupae 12hr  (2012) white prepupae 24hr  (1898) pupae 2d postWPP  (2566) pupae 3d postWPP  (1990) pupae 4d postWPP    1095 adult male 01day    1321 adult male 05day    1215 adult male 30day    1112 adult female 01day  (3191) adult female 05day  (6558) adult female 30day  (6526) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    6873 embryo 02-04hr    7878 embryo 04-06hr    5458 embryo 06-08hr    4558 embryo 08-10hr    5275 embryo 10-12hr    4653 embryo 12-14hr    5213 embryo 14-16hr    2797 embryo 16-18hr    2836 embryo 18-20hr    2082 embryo 20-22hr    2743 embryo 22-24hr    3065 larva L1    5341 larva L2    5393 larva L3 12hr old    3553 larva L3 puffstage 1-2    1969 larva L3 puffstage 3-6    2312 larva L3 puffstage 7-9    3100 white prepupae new    2728 white prepupae 12hr    2012 white prepupae 24hr    1898 pupae 2d postWPP    2566 pupae 3d postWPP    1990 pupae 4d postWPP    1095 adult male 01day    1321 adult male 05day    1215 adult male 30day    1112 adult female 01day    3191 adult female 05day    6558 adult female 30day    6526 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    6873 embryo 02-04hr    7878 embryo 04-06hr    5458 embryo 06-08hr    4558 embryo 08-10hr    5275 embryo 10-12hr    4653 embryo 12-14hr    5213 embryo 14-16hr    2797 embryo 16-18hr    2836 embryo 18-20hr    2082 embryo 20-22hr    2743 embryo 22-24hr    3065 larva L1    5341 larva L2    5393 larva L3 12hr old    3553 larva L3 puffstage 1-2    1969 larva L3 puffstage 3-6    2312 larva L3 puffstage 7-9    3100 white prepupae new    2728 white prepupae 12hr    2012 white prepupae 24hr    1898 pupae 2d postWPP    2566 pupae 3d postWPP    1990 pupae 4d postWPP    1095 adult male 01day    1321 adult male 05day    1215 adult male 30day    1112 adult female 01day    3191 adult female 05day    6558 adult female 30day    6526 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0037652 expression level Developmental Stage   Expression Level embryo 00-02hr    6873 embryo 02-04hr    7878 embryo 04-06hr    5458 embryo 06-08hr    4558 embryo 08-10hr    5275 embryo 10-12hr    4653 embryo 12-14hr    5213 embryo 14-16hr    2797 embryo 16-18hr    2836 embryo 18-20hr    2082 embryo 20-22hr    2743 embryo 22-24hr    3065 larva L1    5341 larva L2    5393 larva L3 12hr old    3553 larva L3 puffstage 1-2    1969 larva L3 puffstage 3-6    2312 larva L3 puffstage 7-9    3100 white prepupae new    2728 white prepupae 12hr    2012 white prepupae 24hr    1898 pupae 2d postWPP    2566 pupae 3d postWPP    1990 pupae 4d postWPP    1095 adult male 01day    1321 adult male 05day    1215 adult male 30day    1112 adult female 01day    3191 adult female 05day    6558 adult female 30day    6526 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (6873) embryo 02-04hr  (7878) embryo 04-06hr  (5458) embryo 06-08hr  (4558) embryo 08-10hr  (5275) embryo 10-12hr  (4653) embryo 12-14hr  (5213) embryo 14-16hr  (2797) embryo 16-18hr  (2836) embryo 18-20hr  (2082) embryo 20-22hr  (2743) embryo 22-24hr  (3065) larva L1  (5341) larva L2  (5393) larva L3 12hr old  (3553) larva L3 puffstage 1-2  (1969) larva L3 puffstage 3-6  (2312) larva L3 puffstage 7-9  (3100) white prepupae new  (2728) white prepupae 12hr  (2012) white prepupae 24hr  (1898) pupae 2d postWPP  (2566) pupae 3d postWPP  (1990) pupae 4d postWPP  (1095) adult male 01day  (1321) adult male 05day  (1215) adult male 30day  (1112) adult female 01day  (3191) adult female 05day  (6558) adult female 30day  (6526) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (6873) embryo 02-04hr  (7878) embryo 04-06hr  (5458) embryo 06-08hr  (4558) embryo 08-10hr  (5275) embryo 10-12hr  (4653) embryo 12-14hr  (5213) embryo 14-16hr  (2797) embryo 16-18hr  (2836) embryo 18-20hr  2082 embryo 20-22hr  (2743) embryo 22-24hr  (3065) larva L1  (5341) larva L2  (5393) larva L3 12hr old  (3553) larva L3 puffstage 1-2  1969 larva L3 puffstage 3-6  2312 larva L3 puffstage 7-9  (3100) white prepupae new  (2728) white prepupae 12hr  2012 white prepupae 24hr  1898 pupae 2d postWPP  (2566) pupae 3d postWPP  1990 pupae 4d postWPP    1095 adult male 01day    1321 adult male 05day    1215 adult male 30day    1112 adult female 01day  (3191) adult female 05day  (6558) adult female 30day  (6526) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    6873 embryo 02-04hr    7878 embryo 04-06hr    5458 embryo 06-08hr    4558 embryo 08-10hr    5275 embryo 10-12hr    4653 embryo 12-14hr    5213 embryo 14-16hr    2797 embryo 16-18hr    2836 embryo 18-20hr    2082 embryo 20-22hr    2743 embryo 22-24hr    3065 larva L1    5341 larva L2    5393 larva L3 12hr old    3553 larva L3 puffstage 1-2    1969 larva L3 puffstage 3-6    2312 larva L3 puffstage 7-9    3100 white prepupae new    2728 white prepupae 12hr    2012 white prepupae 24hr    1898 pupae 2d postWPP    2566 pupae 3d postWPP    1990 pupae 4d postWPP    1095 adult male 01day    1321 adult male 05day    1215 adult male 30day    1112 adult female 01day    3191 adult female 05day    6558 adult female 30day    6526 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    6873 embryo 02-04hr    7878 embryo 04-06hr    5458 embryo 06-08hr    4558 embryo 08-10hr    5275 embryo 10-12hr    4653 embryo 12-14hr    5213 embryo 14-16hr    2797 embryo 16-18hr    2836 embryo 18-20hr    2082 embryo 20-22hr    2743 embryo 22-24hr    3065 larva L1    5341 larva L2    5393 larva L3 12hr old    3553 larva L3 puffstage 1-2    1969 larva L3 puffstage 3-6    2312 larva L3 puffstage 7-9    3100 white prepupae new    2728 white prepupae 12hr    2012 white prepupae 24hr    1898 pupae 2d postWPP    2566 pupae 3d postWPP    1990 pupae 4d postWPP    1095 adult male 01day    1321 adult male 05day    1215 adult male 30day    1112 adult female 01day    3191 adult female 05day    6558 adult female 30day    6526 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0037652    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0037652 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0037652 expression level Tissue   Expression Level Larval Central Nervous System    260.925 Larval Midgut    120.3 Larval Hindgut    229 Larval Malpighian Tubules    184.8 Larval Fat Body    177.6 Larval Salivary Gland    359.7 Larval Trachea    258.05 Larval Carcass    240.725 Adult Head    128.9 Adult Eye    162.85 Adult Brain    118.4 Adult Thoracic-Abdominal Ganglion    101.4 Adult Crop    237.2 Adult Midgut    172.2 Adult Hindgut    217.5 Adult Malpighian Tubules    188.1 Adult Fat Body    203.9 Adult Salivary Gland    257.1 Adult Heart    202.8 Adult VirginFemale Spermatheca    164.7 Adult InseminatedFemale Spermatheca    202 Adult Ovary    408.9 Adult Testis    57.1 Adult Male Accessory Gland    389.7 Adult Carcass    148.5 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    260.925 Larval Midgut    120.3 Larval Hindgut    229 Larval Malpighian Tubules    184.8 Larval Fat Body    177.6 Larval Salivary Gland    359.7 Larval Trachea    258.05 Larval Carcass    240.725 Adult Head    128.9 Adult Eye    162.85 Adult Brain    118.4 Adult Thoracic-Abdominal Ganglion    101.4 Adult Crop    237.2 Adult Midgut    172.2 Adult Hindgut    217.5 Adult Malpighian Tubules    188.1 Adult Fat Body    203.9 Adult Salivary Gland    257.1 Adult Heart    202.8 Adult VirginFemale Spermatheca    164.7 Adult InseminatedFemale Spermatheca    202 Adult Ovary    408.9 Adult Testis    57.1 Adult Male Accessory Gland    389.7 Adult Carcass    148.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    260.925 Larval Midgut    120.3 Larval Hindgut    229 Larval Malpighian Tubules    184.8 Larval Fat Body    177.6 Larval Salivary Gland    359.7 Larval Trachea    258.05 Larval Carcass    240.725 Adult Head    128.9 Adult Eye    162.85 Adult Brain    118.4 Adult Thoracic-Abdominal Ganglion    101.4 Adult Crop    237.2 Adult Midgut    172.2 Adult Hindgut    217.5 Adult Malpighian Tubules    188.1 Adult Fat Body    203.9 Adult Salivary Gland    257.1 Adult Heart    202.8 Adult VirginFemale Spermatheca    164.7 Adult InseminatedFemale Spermatheca    202 Adult Ovary    408.9 Adult Testis    57.1 Adult Male Accessory Gland    389.7 Adult Carcass    148.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    260.925 Larval Midgut    120.3 Larval Hindgut    229 Larval Malpighian Tubules    184.8 Larval Fat Body    177.6 Larval Salivary Gland    359.7 Larval Trachea    258.05 Larval Carcass    240.725 Adult Head    128.9 Adult Eye    162.85 Adult Brain    118.4 Adult Thoracic-Abdominal Ganglion    101.4 Adult Crop    237.2 Adult Midgut    172.2 Adult Hindgut    217.5 Adult Malpighian Tubules    188.1 Adult Fat Body    203.9 Adult Salivary Gland    257.1 Adult Heart    202.8 Adult VirginFemale Spermatheca    164.7 Adult InseminatedFemale Spermatheca    202 Adult Ovary    408.9 Adult Testis    57.1 Adult Male Accessory Gland    389.7 Adult Carcass    148.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0037652 expression level Tissue   Expression Level Larval Central Nervous System    260.925 Larval Midgut    120.3 Larval Hindgut    229 Larval Malpighian Tubules    184.8 Larval Fat Body    177.6 Larval Salivary Gland    359.7 Larval Trachea    258.05 Larval Carcass    240.725 Adult Head    128.9 Adult Eye    162.85 Adult Brain    118.4 Adult Thoracic-Abdominal Ganglion    101.4 Adult Crop    237.2 Adult Midgut    172.2 Adult Hindgut    217.5 Adult Malpighian Tubules    188.1 Adult Fat Body    203.9 Adult Salivary Gland    257.1 Adult Heart    202.8 Adult VirginFemale Spermatheca    164.7 Adult InseminatedFemale Spermatheca    202 Adult Ovary    408.9 Adult Testis    57.1 Adult Male Accessory Gland    389.7 Adult Carcass    148.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    260.925 Larval Midgut    120.3 Larval Hindgut    229 Larval Malpighian Tubules    184.8 Larval Fat Body    177.6 Larval Salivary Gland    359.7 Larval Trachea    258.05 Larval Carcass    240.725 Adult Head    128.9 Adult Eye    162.85 Adult Brain    118.4 Adult Thoracic-Abdominal Ganglion    101.4 Adult Crop    237.2 Adult Midgut    172.2 Adult Hindgut    217.5 Adult Malpighian Tubules    188.1 Adult Fat Body    203.9 Adult Salivary Gland    257.1 Adult Heart    202.8 Adult VirginFemale Spermatheca    164.7 Adult InseminatedFemale Spermatheca    202 Adult Ovary    408.9 Adult Testis    57.1 Adult Male Accessory Gland    389.7 Adult Carcass    148.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    260.925 Larval Midgut    120.3 Larval Hindgut    229 Larval Malpighian Tubules    184.8 Larval Fat Body    177.6 Larval Salivary Gland    359.7 Larval Trachea    258.05 Larval Carcass    240.725 Adult Head    128.9 Adult Eye    162.85 Adult Brain    118.4 Adult Thoracic-Abdominal Ganglion    101.4 Adult Crop    237.2 Adult Midgut    172.2 Adult Hindgut    217.5 Adult Malpighian Tubules    188.1 Adult Fat Body    203.9 Adult Salivary Gland    257.1 Adult Heart    202.8 Adult VirginFemale Spermatheca    164.7 Adult InseminatedFemale Spermatheca    202 Adult Ovary    408.9 Adult Testis    57.1 Adult Male Accessory Gland    389.7 Adult Carcass    148.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    260.925 Larval Midgut    120.3 Larval Hindgut    229 Larval Malpighian Tubules    184.8 Larval Fat Body    177.6 Larval Salivary Gland    359.7 Larval Trachea    258.05 Larval Carcass    240.725 Adult Head    128.9 Adult Eye    162.85 Adult Brain    118.4 Adult Thoracic-Abdominal Ganglion    101.4 Adult Crop    237.2 Adult Midgut    172.2 Adult Hindgut    217.5 Adult Malpighian Tubules    188.1 Adult Fat Body    203.9 Adult Salivary Gland    257.1 Adult Heart    202.8 Adult VirginFemale Spermatheca    164.7 Adult InseminatedFemale Spermatheca    202 Adult Ovary    408.9 Adult Testis    57.1 Adult Male Accessory Gland    389.7 Adult Carcass    148.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    128.9   NA  Eye    162.85   NA  Brain    118.4   260.925  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    101.4   NA  Crop    237.2   120.3  Midgut    172.2   229  Hindgut    217.5   184.8  Malpighian Tubules    188.1   177.6  Fat Body    203.9   359.7  Salivary Gland    257.1   NA  Heart    202.8   258.05  Trachea    NA   NA  VirginFemale Spermatheca    164.7   NA  InseminatedFemale Spermatheca    202   NA  Ovary    408.9   NA  Testis    57.1   NA  Male Accessory Gland    389.7   240.725  Carcass    148.5 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_03
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037652 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11980-RB FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG11980 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG11980GD7448 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG11980 Class Mutagen Stocks Known lesion CG11980DG30808 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG11980 Class Mutagen Stocks Known lesion CG11980GD7448 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6258 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7448} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{wHy}CG11980DG30808 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
	There is no information supporting a biological process, cellular component or molecular function term for this gene. (Based on a review of available data on: 2010-03-25)
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG11980 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0037652 DroID - A comprehensive database of gene and protein interactions. • FBgn0037652 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41078
Orthologs
Genome-wide drosophilid orthologs	Dana\GF16574 Dere\GG14318 Dgri\GH19378 Dmoj\GI22581 Dper\GL12112 Dpse\GA11307 Dsec\GM23777 Dsim\GD18587 Dvir\GJ10302 Dwil\GK11675 Dyak\GE25920
Curated drosophilid orthologs	Dpse\GA11307
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL007356-PB Aedes aegypti (mosquito) AGAP002408-PA Anopheles gambiae (mosquito) XP_623698.1 Apis mellifera (honey bee) XP_001947583.1 Acyrthosiphon pisum (pea aphid) XP_001951635.1 Acyrthosiphon pisum (pea aphid) At5g41970.1 Arabidopsis thaliana (wall cress) 9327 Batrachochytrium dendrobatidis (chytrid fungus) 88459 Branchiostoma floridae (lancelet) BGIBMGA008699-PA Bombyx mori (silk worm) ENSBTAP00000026875 Bos taurus (bovine) CAL0002719 Candida albicans (a form of yeast) CN18430 Caenorhabditis brenneri (small nematode) CBP04493 Caenorhabditis briggsae (nematode) CE18880 Caenorhabditis elegans (worm) ENSCAFP00000010395 Canis familiaris (dog) CAGL0I08547g Candida glabrata (haploid yeast) ENSCINP00000014124 Ciona intestinalis (sea squirt) JA01425 Caenorhabditis japonica (nematode) CMS088C Cyanidioschyzon merolae (red alga) cn04254 Cryptococcus neoformans (yeast-like fungus) CPIJ019665 Culex pipens (mosquito) ENSCPOP00000015271 Cavia porcellus (guinea pig) 123048 Chlamidomonas reinhardtii (green alga) RP11187 Caenorhabditis remanei (nematode) ENSCSAVP00000019267 Ciona savignyi (sedentary tunicate) 225005 Capitella spl (polychaete worm) DDB0238598 Dictyostelium discoideum (amoeba) DEHA2C02574g Debaryomyces Hansenii (yeast) 308656 Daphnia pulex (daphnia) ENSDARP00000093070 Danio rerio (zebra fish) ENSECAP00000009272 Equus caballus (horse) XP_650444 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000009004 Gymnopilus aculeatus (mushroom) ENSGALP00000022078 Gallus gallus (chicken) GL50803_10858 Giardia lamblia (flagellated protozoan) 192998 Hypsipyla robusta (cedar shoot borer) ENSP00000267103 Homo sapiens (human) ISCW012565-PA Ixodes scapularis (deer tick) KLLA0C11671g Kluyveromyces lactis (yeast) 122169 Lottia gigantea (owl limpet) LmjF09.0840 Leishmania major (virus) 20236 Monocosta brevicollis (choanoflagellate) ENSMMUP00000029020 Macaca mulatta (rhesus monkey) ENSMUSP00000001331 Mus musculus (house mouse) 105041 Nematostella vectensis (starlet anemone) XP_001601011.1 Nasonia vitripennis (wasp) ENSORLP00000006456 Oryzias latipes (japanese killifish) LOC_Os02g46150.1 Oryza sativa (asian rice) 22966 Ostreococcus tauri (green alga) PFF1295w Plasmodium falciparum (protozoal parasite) PHUM000125-PA Pediculus humanus (human body louse) PP24600 Pristionchus pacificus (nematode) 128158 Physcomitrella patens (moss) ENSPPYP00000005220 Pongo pygmaeus (orangutan) 71125 Phytophthora ramorum (sudden oak death pathogen) 108501 Phytophthora sojae (root rot pathogen) 830885 Populus trichocarpa (black cottonwood) ENSPTRP00000008531 Pan troglodytes (chimpanzee) PVX_114440 Plasmodium vivax (protozoal parasite) ENSRNOP00000017942 Rattus norvegicus (norway rat) 4979893 Sorghum bicolor (sorghum) YER156C Saccharomyces cerevisiae (budding yeast) Smp_024490 Schistosoma mansoni (trematode parasite) SPAC694.04c Schizosaccharomyces pombe (fission yeast) XP_001204404.1 Strongylocentrotus purpuratus (purple sea urchin) 52107 Trichoplax adhaerens (metazoa) TA11240 Theileria annulata (apicomplexan parasite) XP_972332.1 Tribolium castaneum (red flour beetle) Tc00.1047053505171.60 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053511559.20 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000017868 Tetraodon nigroviridis (green spotted pufferfish) TP04_0850 Theileria parva (parasitic protozoan) 832 Thalassiosira pseudonana (marine diatom) ENSTRUP00000028071 Takifugu rubripes (pufferfish Takifugu) 143.m00076 Tetrahymena thermophila (ciliate protozoa) 97153.m00048 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000027716 Xenopus tropicalis (frog) YALI0D24970g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV17192 LH24470 ISCW012565 FBgn0242969 FBgn0213686 FBgn0197588 FBgn0190109 FBgn0178642 FBgn0174172 JGI_V11_308656 FBgn0071361 FBgn0149720 FBgn0145309 FBgn0126843 FBgn0106579 FBgn0093595 CPIJ014585 CPIJ019665 BGIBMGA008699 ACYPI006831 ACYPI006340 GB20125 AGAP002408 AAEL007356 PB24998 PHUM275760 GLEAN_13284
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	21349 y1 w67c23; P{wHy}CG11980DG30808
VDRC	v38617 w1118; P{GD7448}v38617 v38616 w1118; P{GD7448}v38616/CyO
Genomic Clones ( 2 )
	BACR02G22 BACR09F04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 87 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD44814 RE51612
Other clones	DPiM_RE51612
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM01431 GM05205 GM14049 GM15840 GM16841 LD01982 LD32468 LD35604 LD35681 LD39527 LD42782 RE05760 RE10482 RE10938 RE24433 RE32259 RE59358 RE62320 RE62920 RE70331 RE74003
Other clones	Dmel_neb_010921_0654_2518 EK154001 EK160161 EK169519 EK177406 EK231805 RP01523 RP001002794 RP001005565 RP001006654 RP001007573 RP001008416 RP001011418 RP001012166 RP001013636 RP001015787 RP001016731 RP001017416 RP001018022 RP001020048 RP001020095 RP001020148 RP001021896 RP001022847 RP001022901 RP001023736 RP001024203 RP001024236 RP001024578 RP001026168 RP001034481 RP001036492 RP001037083 RP001037161 RP001037381 RP001037418 RP001038590 RP001038749 RP001038882 RP001038910 RP001039030 RP001039497 RP001039900 RP001041322 RP001041759 RP001041839 RP001042136 RP001042317 RP001044310 RP001044326 RP001045907 RP001047508 RP001049314 RP001053387 RP001053484 RP001053630 RP001053905 RP001054571 RP001054641 RP001054652 RP001055055 RP001055353 RP001055900
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0037652 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41078
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG11980 anon-WO0118547.327 (FlyBase, 1996-)
Additional comments	Source for merge of CG11980 anon-WO0118547.327 was sequence comparison (date:051113). (FlyBase, 1996-)
Other Comments
	Area matching Drosophila EST AA202487. This EST has sequence similarity to Yeast YEY6 gene. (Davies, 2001.3.15)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_141600 NM_169250 NM_169251 RefSeq (Proteins) • NP_649857 NP_731302 NP_731303 DDBJ / EMBL / GenBank • AA202487 AAF54319 AAM75044 AAN13404 AAN13405 AI512784 AX094203 AY128451 BI366147 Entrez Gene - A searchable database of RefSeq genes. • 41078 UniProtKB/TrEMBL • Q8INP8 Q8INP9 Q8MQQ5 Q9VHI8
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Thioredoxin-like fold (IPR012336) Metal-dependent protein hydrolase (IPR003226)
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0037652 DroID - A comprehensive database of gene and protein interactions. • FBgn0037652 DRSC - Results from RNAi screens. • FBgn0037652 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037652 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11980-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0037652 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41078 InParanoid A subset of ortholog calls from InParanoid. • AAEL007356-PB Aedes aegypti (mosquito) AGAP002408-PA Anopheles gambiae (mosquito) XP_623698.1 Apis mellifera (honey bee) XP_001947583.1 Acyrthosiphon pisum (pea aphid) XP_001951635.1 Acyrthosiphon pisum (pea aphid) At5g41970.1 Arabidopsis thaliana (wall cress) 9327 Batrachochytrium dendrobatidis (chytrid fungus) 88459 Branchiostoma floridae (lancelet) BGIBMGA008699-PA Bombyx mori (silk worm) ENSBTAP00000026875 Bos taurus (bovine) CAL0002719 Candida albicans (a form of yeast) CN18430 Caenorhabditis brenneri (small nematode) CBP04493 Caenorhabditis briggsae (nematode) CE18880 Caenorhabditis elegans (worm) ENSCAFP00000010395 Canis familiaris (dog) CAGL0I08547g Candida glabrata (haploid yeast) ENSCINP00000014124 Ciona intestinalis (sea squirt) JA01425 Caenorhabditis japonica (nematode) CMS088C Cyanidioschyzon merolae (red alga) cn04254 Cryptococcus neoformans (yeast-like fungus) CPIJ019665 Culex pipens (mosquito) ENSCPOP00000015271 Cavia porcellus (guinea pig) 123048 Chlamidomonas reinhardtii (green alga) RP11187 Caenorhabditis remanei (nematode) ENSCSAVP00000019267 Ciona savignyi (sedentary tunicate) 225005 Capitella spl (polychaete worm) DDB0238598 Dictyostelium discoideum (amoeba) DEHA2C02574g Debaryomyces Hansenii (yeast) 308656 Daphnia pulex (daphnia) ENSDARP00000093070 Danio rerio (zebra fish) ENSECAP00000009272 Equus caballus (horse) XP_650444 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000009004 Gymnopilus aculeatus (mushroom) ENSGALP00000022078 Gallus gallus (chicken) GL50803_10858 Giardia lamblia (flagellated protozoan) 192998 Hypsipyla robusta (cedar shoot borer) ENSP00000267103 Homo sapiens (human) ISCW012565-PA Ixodes scapularis (deer tick) KLLA0C11671g Kluyveromyces lactis (yeast) 122169 Lottia gigantea (owl limpet) LmjF09.0840 Leishmania major (virus) 20236 Monocosta brevicollis (choanoflagellate) ENSMMUP00000029020 Macaca mulatta (rhesus monkey) ENSMUSP00000001331 Mus musculus (house mouse) 105041 Nematostella vectensis (starlet anemone) XP_001601011.1 Nasonia vitripennis (wasp) ENSORLP00000006456 Oryzias latipes (japanese killifish) LOC_Os02g46150.1 Oryza sativa (asian rice) 22966 Ostreococcus tauri (green alga) PFF1295w Plasmodium falciparum (protozoal parasite) PHUM000125-PA Pediculus humanus (human body louse) PP24600 Pristionchus pacificus (nematode) 128158 Physcomitrella patens (moss) ENSPPYP00000005220 Pongo pygmaeus (orangutan) 71125 Phytophthora ramorum (sudden oak death pathogen) 108501 Phytophthora sojae (root rot pathogen) 830885 Populus trichocarpa (black cottonwood) ENSPTRP00000008531 Pan troglodytes (chimpanzee) PVX_114440 Plasmodium vivax (protozoal parasite) ENSRNOP00000017942 Rattus norvegicus (norway rat) 4979893 Sorghum bicolor (sorghum) YER156C Saccharomyces cerevisiae (budding yeast) Smp_024490 Schistosoma mansoni (trematode parasite) SPAC694.04c Schizosaccharomyces pombe (fission yeast) XP_001204404.1 Strongylocentrotus purpuratus (purple sea urchin) 52107 Trichoplax adhaerens (metazoa) TA11240 Theileria annulata (apicomplexan parasite) XP_972332.1 Tribolium castaneum (red flour beetle) Tc00.1047053505171.60 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053511559.20 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000017868 Tetraodon nigroviridis (green spotted pufferfish) TP04_0850 Theileria parva (parasitic protozoan) 832 Thalassiosira pseudonana (marine diatom) ENSTRUP00000028071 Takifugu rubripes (pufferfish Takifugu) 143.m00076 Tetrahymena thermophila (ciliate protozoa) 97153.m00048 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000027716 Xenopus tropicalis (frog) YALI0D24970g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41078 modMine - Data generated by the modENCODE project. • FBgn0037652 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV17192 LH24470 ISCW012565 FBgn0242969 FBgn0213686 FBgn0197588 FBgn0190109 FBgn0178642 FBgn0174172 JGI_V11_308656 FBgn0071361 FBgn0149720 FBgn0145309 FBgn0126843 FBgn0106579 FBgn0093595 CPIJ014585 CPIJ019665 BGIBMGA008699 ACYPI006831 ACYPI006340 GB20125 AGAP002408 AAEL007356 PB24998 PHUM275760 GLEAN_13284
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	anon-WO0118547.327   CG11980 (Georlette et al., 2007, Weiler, 2007)
Name Synonym
Secondary FlyBase IDs
	FBgn0062091
References ( 15 )
Research paper	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Georlette et al., 2007, Genes Dev. 21(22): 2880--2896 Genomic profiling and expression studies reveal both positive and negative activities for the Drosophila Myb-MuvB/dREAM complex in proliferating cells. [FBrf0202703] Weiler, 2007, Genetics 177(1): 167--178 E(var)3-9 of Drosophila melanogaster Encodes a Zinc Finger Protein. [FBrf0201244] Gong et al., 2004, Development 131(3): 643--656 Drosophila ventral furrow morphogenesis: a proteomic analysis. [FBrf0167535]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Gelbart, 2008.3.31, DG.xml DG.xml [FBrf0204101] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Myrick et al., 2005.5.16, Deletion Generator Project genomic insertion collection. Deletion Generator Project genomic insertion collection. [FBrf0188490] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398] FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946]
Patent	Davies et al., 2001, World Patent 0118547: Essential genes and assays relating thereto. [FBrf0199103]
DNA/RNA sequence record	Davies, 2001.3.15, GenBank/EMBL/DDBJ: AX094203 Sequence 327 from Patent WO0118547. [FBrf0150032]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]