Gene Dmel\CG11986

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General Information

Symbol

Dmel\CG11986

Species

D. melanogaster

Name

Annotation symbol

CG11986

Feature type

protein_coding_gene

FlyBase ID

FBgn0037656

Gene Model Status

Current

Stock availability

3 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

85C2-85C2

Sequence location

3R:4,841,168..4,842,544 [+]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG11986 (FBgn0037656). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Protein of unknown function DUF159. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1638463_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG11986. Gene sequence location is 3R:4841168..4842544.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

85C2-85C2

Limits computationally determined from genome sequence between P{lacW}l(3)L4740^L4740 and P{EP}D1^EP473

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG11986 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.48

Low-frequency RNA-Seq exon junction(s) not annotated.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG11986-RA

FBtr0081967

NM_141605

1262

368

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG11986-PA

FBpp0081447

42.5

368

8.45

NP_649862

AAF54328

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Protein of unknown function DUF159 (IPR003738)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q9VHI3

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		43.875
Larval Midgut		24.4
Larval Hindgut		31.3
Larval Malpighian Tubules		99.8
Larval Fat Body		26
Larval Salivary Gland		25.6
Larval Trachea		27.825
Larval Carcass		13.65
Adult Head		10.6
Adult Eye		14.8
Adult Brain		26.7
Adult Thoracic-Abdominal Ganglion		34.2
Adult Crop		28
Adult Midgut		30.3
Adult Hindgut		21.2
Adult Malpighian Tubules		58.2
Adult Fat Body		10.7
Adult Salivary Gland		27.4
Adult Heart		19.425
Adult VirginFemale Spermatheca		6.9
Adult InseminatedFemale Spermatheca		6.6
Adult Ovary		69.9
Adult Testis		86.6
Adult Male Accessory Gland		12.9
Adult Carcass		15.3
Expression Level Scale		None Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		43.875
Larval Midgut		24.4
Larval Hindgut		31.3
Larval Malpighian Tubules		99.8
Larval Fat Body		26
Larval Salivary Gland		25.6
Larval Trachea		27.825
Larval Carcass		13.65
Adult Head		10.6
Adult Eye		14.8
Adult Brain		26.7
Adult Thoracic-Abdominal Ganglion		34.2
Adult Crop		28
Adult Midgut		30.3
Adult Hindgut		21.2
Adult Malpighian Tubules		58.2
Adult Fat Body		10.7
Adult Salivary Gland		27.4
Adult Heart		19.425
Adult VirginFemale Spermatheca		6.9
Adult InseminatedFemale Spermatheca		6.6
Adult Ovary		69.9
Adult Testis		86.6
Adult Male Accessory Gland		12.9
Adult Carcass		15.3
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		43.875
Larval Midgut		24.4
Larval Hindgut		31.3
Larval Malpighian Tubules		99.8
Larval Fat Body		26
Larval Salivary Gland		25.6
Larval Trachea		27.825
Larval Carcass		13.65
Adult Head		10.6
Adult Eye		14.8
Adult Brain		26.7
Adult Thoracic-Abdominal Ganglion		34.2
Adult Crop		28
Adult Midgut		30.3
Adult Hindgut		21.2
Adult Malpighian Tubules		58.2
Adult Fat Body		10.7
Adult Salivary Gland		27.4
Adult Heart		19.425
Adult VirginFemale Spermatheca		6.9
Adult InseminatedFemale Spermatheca		6.6
Adult Ovary		69.9
Adult Testis		86.6
Adult Male Accessory Gland		12.9
Adult Carcass		15.3
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		43.875
Larval Midgut		24.4
Larval Hindgut		31.3
Larval Malpighian Tubules		99.8
Larval Fat Body		26
Larval Salivary Gland		25.6
Larval Trachea		27.825
Larval Carcass		13.65
Adult Head		10.6
Adult Eye		14.8
Adult Brain		26.7
Adult Thoracic-Abdominal Ganglion		34.2
Adult Crop		28
Adult Midgut		30.3
Adult Hindgut		21.2
Adult Malpighian Tubules		58.2
Adult Fat Body		10.7
Adult Salivary Gland		27.4
Adult Heart		19.425
Adult VirginFemale Spermatheca		6.9
Adult InseminatedFemale Spermatheca		6.6
Adult Ovary		69.9
Adult Testis		86.6
Adult Male Accessory Gland		12.9
Adult Carcass		15.3
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		43.875
Larval Midgut		24.4
Larval Hindgut		31.3
Larval Malpighian Tubules		99.8
Larval Fat Body		26
Larval Salivary Gland		25.6
Larval Trachea		27.825
Larval Carcass		13.65
Adult Head		10.6
Adult Eye		14.8
Adult Brain		26.7
Adult Thoracic-Abdominal Ganglion		34.2
Adult Crop		28
Adult Midgut		30.3
Adult Hindgut		21.2
Adult Malpighian Tubules		58.2
Adult Fat Body		10.7
Adult Salivary Gland		27.4
Adult Heart		19.425
Adult VirginFemale Spermatheca		6.9
Adult InseminatedFemale Spermatheca		6.6
Adult Ovary		69.9
Adult Testis		86.6
Adult Male Accessory Gland		12.9
Adult Carcass		15.3
Expression Level Scale		None Low Moderate

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		43.875
Larval Midgut		24.4
Larval Hindgut		31.3
Larval Malpighian Tubules		99.8
Larval Fat Body		26
Larval Salivary Gland		25.6
Larval Trachea		27.825
Larval Carcass		13.65
Adult Head		10.6
Adult Eye		14.8
Adult Brain		26.7
Adult Thoracic-Abdominal Ganglion		34.2
Adult Crop		28
Adult Midgut		30.3
Adult Hindgut		21.2
Adult Malpighian Tubules		58.2
Adult Fat Body		10.7
Adult Salivary Gland		27.4
Adult Heart		19.425
Adult VirginFemale Spermatheca		6.9
Adult InseminatedFemale Spermatheca		6.6
Adult Ovary		69.9
Adult Testis		86.6
Adult Male Accessory Gland		12.9
Adult Carcass		15.3
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		43.875
Larval Midgut		24.4
Larval Hindgut		31.3
Larval Malpighian Tubules		99.8
Larval Fat Body		26
Larval Salivary Gland		25.6
Larval Trachea		27.825
Larval Carcass		13.65
Adult Head		10.6
Adult Eye		14.8
Adult Brain		26.7
Adult Thoracic-Abdominal Ganglion		34.2
Adult Crop		28
Adult Midgut		30.3
Adult Hindgut		21.2
Adult Malpighian Tubules		58.2
Adult Fat Body		10.7
Adult Salivary Gland		27.4
Adult Heart		19.425
Adult VirginFemale Spermatheca		6.9
Adult InseminatedFemale Spermatheca		6.6
Adult Ovary		69.9
Adult Testis		86.6
Adult Male Accessory Gland		12.9
Adult Carcass		15.3
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		43.875
Larval Midgut		24.4
Larval Hindgut		31.3
Larval Malpighian Tubules		99.8
Larval Fat Body		26
Larval Salivary Gland		25.6
Larval Trachea		27.825
Larval Carcass		13.65
Adult Head		10.6
Adult Eye		14.8
Adult Brain		26.7
Adult Thoracic-Abdominal Ganglion		34.2
Adult Crop		28
Adult Midgut		30.3
Adult Hindgut		21.2
Adult Malpighian Tubules		58.2
Adult Fat Body		10.7
Adult Salivary Gland		27.4
Adult Heart		19.425
Adult VirginFemale Spermatheca		6.9
Adult InseminatedFemale Spermatheca		6.6
Adult Ovary		69.9
Adult Testis		86.6
Adult Male Accessory Gland		12.9
Adult Carcass		15.3
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	no informative data
NA	Eye	no informative data
NA	Brain	26.7
43.875	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	34.2
NA	Crop	28
24.4	Midgut	30.3
31.3	Hindgut	21.2
99.8	Malpighian Tubules	58.2
no informative data	Fat Body	no informative data
25.6	Salivary Gland	27.4
NA	Heart	19.425
27.825	Trachea	NA
NA	VirginFemale Spermatheca	6.9
NA	InseminatedFemale Spermatheca	6.6
NA	Ovary	69.9
NA	Testis	86.6
NA	Male Accessory Gland	no informative data
no informative data	Carcass	15.3

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		17
central nervous system, larvae L3		5
central nervous system, pupae P8		2
head, virgin 1-day female		2
head, virgin 4-day female		0
head, virgin 20-day female		2
head, mated 1-day female		1
head, mated 4-day female		2
head, mated 20-day female		1
head, mated 1-day male		2
head, mated 4-day male		1
head, mated 20-day male		2
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		3
digestive system, 4-day adult		3
digestive system, 20-day adult		3
fat body, larvae L3 wandering		0
fat body, white prepupae		2
fat body, pupae P8		5
carcass, larvae L3 wandering		4
carcass, 1-day adult		1
carcass, 4-day adult		1
carcass, 20-day adult		2
ovary, virgin 4-day female		15
ovary, mated 4-day female		10
testis, mated 4-day male		21
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		17
central nervous system, larvae L3		5
central nervous system, pupae P8		2
head, virgin 1-day female		2
head, virgin 4-day female		0
head, virgin 20-day female		2
head, mated 1-day female		1
head, mated 4-day female		2
head, mated 20-day female		1
head, mated 1-day male		2
head, mated 4-day male		1
head, mated 20-day male		2
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		3
digestive system, 4-day adult		3
digestive system, 20-day adult		3
fat body, larvae L3 wandering		0
fat body, white prepupae		2
fat body, pupae P8		5
carcass, larvae L3 wandering		4
carcass, 1-day adult		1
carcass, 4-day adult		1
carcass, 20-day adult		2
ovary, virgin 4-day female		15
ovary, mated 4-day female		10
testis, mated 4-day male		21
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		17
central nervous system, larvae L3		5
central nervous system, pupae P8		2
head, virgin 1-day female		2
head, virgin 4-day female		0
head, virgin 20-day female		2
head, mated 1-day female		1
head, mated 4-day female		2
head, mated 20-day female		1
head, mated 1-day male		2
head, mated 4-day male		1
head, mated 20-day male		2
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		3
digestive system, 4-day adult		3
digestive system, 20-day adult		3
fat body, larvae L3 wandering		0
fat body, white prepupae		2
fat body, pupae P8		5
carcass, larvae L3 wandering		4
carcass, 1-day adult		1
carcass, 4-day adult		1
carcass, 20-day adult		2
ovary, virgin 4-day female		15
ovary, mated 4-day female		10
testis, mated 4-day male		21
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		17
central nervous system, larvae L3		5
central nervous system, pupae P8		2
head, virgin 1-day female		2
head, virgin 4-day female		0
head, virgin 20-day female		2
head, mated 1-day female		1
head, mated 4-day female		2
head, mated 20-day female		1
head, mated 1-day male		2
head, mated 4-day male		1
head, mated 20-day male		2
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		3
digestive system, 4-day adult		3
digestive system, 20-day adult		3
fat body, larvae L3 wandering		0
fat body, white prepupae		2
fat body, pupae P8		5
carcass, larvae L3 wandering		4
carcass, 1-day adult		1
carcass, 4-day adult		1
carcass, 20-day adult		2
ovary, virgin 4-day female		15
ovary, mated 4-day female		10
testis, mated 4-day male		21
accessory gland, mated 4-day male		2
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		17
central nervous system, larvae L3		5
central nervous system, pupae P8		2
head, virgin 1-day female		2
head, virgin 4-day female		0
head, virgin 20-day female		2
head, mated 1-day female		1
head, mated 4-day female		2
head, mated 20-day female		1
head, mated 1-day male		2
head, mated 4-day male		1
head, mated 20-day male		2
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		3
digestive system, 4-day adult		3
digestive system, 20-day adult		3
fat body, larvae L3 wandering		0
fat body, white prepupae		2
fat body, pupae P8		5
carcass, larvae L3 wandering		4
carcass, 1-day adult		1
carcass, 4-day adult		1
carcass, 20-day adult		2
ovary, virgin 4-day female		15
ovary, mated 4-day female		10
testis, mated 4-day male		21
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		17
central nervous system, larvae L3		5
central nervous system, pupae P8		2
head, virgin 1-day female		2
head, virgin 4-day female		0
head, virgin 20-day female		2
head, mated 1-day female		1
head, mated 4-day female		2
head, mated 20-day female		1
head, mated 1-day male		2
head, mated 4-day male		1
head, mated 20-day male		2
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		3
digestive system, 4-day adult		3
digestive system, 20-day adult		3
fat body, larvae L3 wandering		0
fat body, white prepupae		2
fat body, pupae P8		5
carcass, larvae L3 wandering		4
carcass, 1-day adult		1
carcass, 4-day adult		1
carcass, 20-day adult		2
ovary, virgin 4-day female		15
ovary, mated 4-day female		10
testis, mated 4-day male		21
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		17
central nervous system, larvae L3		5
central nervous system, pupae P8		2
head, virgin 1-day female		2
head, virgin 4-day female		0
head, virgin 20-day female		2
head, mated 1-day female		1
head, mated 4-day female		2
head, mated 20-day female		1
head, mated 1-day male		2
head, mated 4-day male		1
head, mated 20-day male		2
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		3
digestive system, 4-day adult		3
digestive system, 20-day adult		3
fat body, larvae L3 wandering		0
fat body, white prepupae		2
fat body, pupae P8		5
carcass, larvae L3 wandering		4
carcass, 1-day adult		1
carcass, 4-day adult		1
carcass, 20-day adult		2
ovary, virgin 4-day female		15
ovary, mated 4-day female		10
testis, mated 4-day male		21
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		17
central nervous system, larvae L3		5
central nervous system, pupae P8		2
head, virgin 1-day female		2
head, virgin 4-day female		0
head, virgin 20-day female		2
head, mated 1-day female		1
head, mated 4-day female		2
head, mated 20-day female		1
head, mated 1-day male		2
head, mated 4-day male		1
head, mated 20-day male		2
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		3
digestive system, 4-day adult		3
digestive system, 20-day adult		3
fat body, larvae L3 wandering		0
fat body, white prepupae		2
fat body, pupae P8		5
carcass, larvae L3 wandering		4
carcass, 1-day adult		1
carcass, 4-day adult		1
carcass, 20-day adult		2
ovary, virgin 4-day female		15
ovary, mated 4-day female		10
testis, mated 4-day male		21
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		26
embryo 04-06hr		27
embryo 06-08hr		23
embryo 08-10hr		23
embryo 10-12hr		14
embryo 12-14hr		10
embryo 14-16hr		7
embryo 16-18hr		6
embryo 18-20hr		4
embryo 20-22hr		4
embryo 22-24hr		5
larva L1		4
larva L2		5
larva L3 12hr old		4
larva L3 puffstage 1-2		6
larva L3 puffstage 3-6		9
larva L3 puffstage 7-9		11
white prepupae new		10
white prepupae 12hr		11
white prepupae 24hr		13
pupae 2d postWPP		10
pupae 3d postWPP		7
pupae 4d postWPP		6
adult male 01day		9
adult male 05day		14
adult male 30day		12
adult female 01day		8
adult female 05day		13
adult female 30day		15
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		26
embryo 04-06hr		(27)
embryo 06-08hr		23
embryo 08-10hr		23
embryo 10-12hr		14
embryo 12-14hr		10
embryo 14-16hr		7
embryo 16-18hr		6
embryo 18-20hr		4
embryo 20-22hr		4
embryo 22-24hr		5
larva L1		4
larva L2		5
larva L3 12hr old		4
larva L3 puffstage 1-2		6
larva L3 puffstage 3-6		9
larva L3 puffstage 7-9		11
white prepupae new		10
white prepupae 12hr		11
white prepupae 24hr		13
pupae 2d postWPP		10
pupae 3d postWPP		7
pupae 4d postWPP		6
adult male 01day		9
adult male 05day		14
adult male 30day		12
adult female 01day		8
adult female 05day		13
adult female 30day		15
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		26
embryo 04-06hr		27
embryo 06-08hr		23
embryo 08-10hr		23
embryo 10-12hr		14
embryo 12-14hr		10
embryo 14-16hr		7
embryo 16-18hr		6
embryo 18-20hr		4
embryo 20-22hr		4
embryo 22-24hr		5
larva L1		4
larva L2		5
larva L3 12hr old		4
larva L3 puffstage 1-2		6
larva L3 puffstage 3-6		9
larva L3 puffstage 7-9		11
white prepupae new		10
white prepupae 12hr		11
white prepupae 24hr		13
pupae 2d postWPP		10
pupae 3d postWPP		7
pupae 4d postWPP		6
adult male 01day		9
adult male 05day		14
adult male 30day		12
adult female 01day		8
adult female 05day		13
adult female 30day		15
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		26
embryo 04-06hr		27
embryo 06-08hr		23
embryo 08-10hr		23
embryo 10-12hr		14
embryo 12-14hr		10
embryo 14-16hr		7
embryo 16-18hr		6
embryo 18-20hr		4
embryo 20-22hr		4
embryo 22-24hr		5
larva L1		4
larva L2		5
larva L3 12hr old		4
larva L3 puffstage 1-2		6
larva L3 puffstage 3-6		9
larva L3 puffstage 7-9		11
white prepupae new		10
white prepupae 12hr		11
white prepupae 24hr		13
pupae 2d postWPP		10
pupae 3d postWPP		7
pupae 4d postWPP		6
adult male 01day		9
adult male 05day		14
adult male 30day		12
adult female 01day		8
adult female 05day		13
adult female 30day		15
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		26
embryo 04-06hr		27
embryo 06-08hr		23
embryo 08-10hr		23
embryo 10-12hr		14
embryo 12-14hr		10
embryo 14-16hr		7
embryo 16-18hr		6
embryo 18-20hr		4
embryo 20-22hr		4
embryo 22-24hr		5
larva L1		4
larva L2		5
larva L3 12hr old		4
larva L3 puffstage 1-2		6
larva L3 puffstage 3-6		9
larva L3 puffstage 7-9		11
white prepupae new		10
white prepupae 12hr		11
white prepupae 24hr		13
pupae 2d postWPP		10
pupae 3d postWPP		7
pupae 4d postWPP		6
adult male 01day		9
adult male 05day		14
adult male 30day		12
adult female 01day		8
adult female 05day		13
adult female 30day		15
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		26
embryo 04-06hr		27
embryo 06-08hr		23
embryo 08-10hr		23
embryo 10-12hr		14
embryo 12-14hr		10
embryo 14-16hr		7
embryo 16-18hr		6
embryo 18-20hr		4
embryo 20-22hr		4
embryo 22-24hr		5
larva L1		4
larva L2		5
larva L3 12hr old		4
larva L3 puffstage 1-2		6
larva L3 puffstage 3-6		9
larva L3 puffstage 7-9		11
white prepupae new		10
white prepupae 12hr		11
white prepupae 24hr		13
pupae 2d postWPP		10
pupae 3d postWPP		7
pupae 4d postWPP		6
adult male 01day		9
adult male 05day		14
adult male 30day		12
adult female 01day		8
adult female 05day		13
adult female 30day		15
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		26
embryo 04-06hr		27
embryo 06-08hr		23
embryo 08-10hr		23
embryo 10-12hr		14
embryo 12-14hr		10
embryo 14-16hr		7
embryo 16-18hr		6
embryo 18-20hr		4
embryo 20-22hr		4
embryo 22-24hr		5
larva L1		4
larva L2		5
larva L3 12hr old		4
larva L3 puffstage 1-2		6
larva L3 puffstage 3-6		9
larva L3 puffstage 7-9		11
white prepupae new		10
white prepupae 12hr		11
white prepupae 24hr		13
pupae 2d postWPP		10
pupae 3d postWPP		7
pupae 4d postWPP		6
adult male 01day		9
adult male 05day		14
adult male 30day		12
adult female 01day		8
adult female 05day		13
adult female 30day		15
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		26
embryo 04-06hr		27
embryo 06-08hr		23
embryo 08-10hr		23
embryo 10-12hr		14
embryo 12-14hr		10
embryo 14-16hr		7
embryo 16-18hr		6
embryo 18-20hr		4
embryo 20-22hr		4
embryo 22-24hr		5
larva L1		4
larva L2		5
larva L3 12hr old		4
larva L3 puffstage 1-2		6
larva L3 puffstage 3-6		9
larva L3 puffstage 7-9		11
white prepupae new		10
white prepupae 12hr		11
white prepupae 24hr		13
pupae 2d postWPP		10
pupae 3d postWPP		7
pupae 4d postWPP		6
adult male 01day		9
adult male 05day		14
adult male 30day		12
adult female 01day		8
adult female 05day		13
adult female 30day		15
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		9
Schneider line 2 Sg4		7
embryonic 1182-4H		7
embryonic GM2		7
embryonic Kc167		11
embryonic S1		9
embryonic S3		11
leg disc CME L1		5
wing disc CME-W2		7
wing disc ML-DmD8		8
wing disc ML-DmD9		6
wing disc ML-DmD16-c3		7
wing disc ML-DmD21		12
wing disc ML-DmD32		8
haltere disc ML-DmD17-c3		13
eye-antennal disc ML-DmD11		7
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		6
CNS ML-DmBG1-c1		9
CNS ML-DmBG2-c2		11
tumorous blood cells mbn2		7
ovary fGS/OSS		8
ovary OSC		5
ovary OSS		5
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		9
Schneider line 2 Sg4		7
embryonic 1182-4H		7
embryonic GM2		7
embryonic Kc167		11
embryonic S1		9
embryonic S3		11
leg disc CME L1		5
wing disc CME-W2		7
wing disc ML-DmD8		8
wing disc ML-DmD9		6
wing disc ML-DmD16-c3		7
wing disc ML-DmD21		12
wing disc ML-DmD32		8
haltere disc ML-DmD17-c3		13
eye-antennal disc ML-DmD11		7
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		6
CNS ML-DmBG1-c1		9
CNS ML-DmBG2-c2		11
tumorous blood cells mbn2		7
ovary fGS/OSS		8
ovary OSC		5
ovary OSS		5
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		9
Schneider line 2 Sg4		7
embryonic 1182-4H		7
embryonic GM2		7
embryonic Kc167		11
embryonic S1		9
embryonic S3		11
leg disc CME L1		5
wing disc CME-W2		7
wing disc ML-DmD8		8
wing disc ML-DmD9		6
wing disc ML-DmD16-c3		7
wing disc ML-DmD21		12
wing disc ML-DmD32		8
haltere disc ML-DmD17-c3		13
eye-antennal disc ML-DmD11		7
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		6
CNS ML-DmBG1-c1		9
CNS ML-DmBG2-c2		11
tumorous blood cells mbn2		7
ovary fGS/OSS		8
ovary OSC		5
ovary OSS		5
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		9
Schneider line 2 Sg4		7
embryonic 1182-4H		7
embryonic GM2		7
embryonic Kc167		11
embryonic S1		9
embryonic S3		11
leg disc CME L1		5
wing disc CME-W2		7
wing disc ML-DmD8		8
wing disc ML-DmD9		6
wing disc ML-DmD16-c3		7
wing disc ML-DmD21		12
wing disc ML-DmD32		8
haltere disc ML-DmD17-c3		13
eye-antennal disc ML-DmD11		7
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		6
CNS ML-DmBG1-c1		9
CNS ML-DmBG2-c2		11
tumorous blood cells mbn2		7
ovary fGS/OSS		8
ovary OSC		5
ovary OSS		5
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		9
Schneider line 2 Sg4		7
embryonic 1182-4H		7
embryonic GM2		7
embryonic Kc167		11
embryonic S1		9
embryonic S3		11
leg disc CME L1		5
wing disc CME-W2		7
wing disc ML-DmD8		8
wing disc ML-DmD9		6
wing disc ML-DmD16-c3		7
wing disc ML-DmD21		12
wing disc ML-DmD32		8
haltere disc ML-DmD17-c3		13
eye-antennal disc ML-DmD11		7
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		6
CNS ML-DmBG1-c1		9
CNS ML-DmBG2-c2		11
tumorous blood cells mbn2		7
ovary fGS/OSS		8
ovary OSC		5
ovary OSS		5
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		9
Schneider line 2 Sg4		7
embryonic 1182-4H		7
embryonic GM2		7
embryonic Kc167		11
embryonic S1		9
embryonic S3		11
leg disc CME L1		5
wing disc CME-W2		7
wing disc ML-DmD8		8
wing disc ML-DmD9		6
wing disc ML-DmD16-c3		7
wing disc ML-DmD21		12
wing disc ML-DmD32		8
haltere disc ML-DmD17-c3		13
eye-antennal disc ML-DmD11		7
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		6
CNS ML-DmBG1-c1		9
CNS ML-DmBG2-c2		11
tumorous blood cells mbn2		7
ovary fGS/OSS		8
ovary OSC		5
ovary OSS		5
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		9
Schneider line 2 Sg4		7
embryonic 1182-4H		7
embryonic GM2		7
embryonic Kc167		11
embryonic S1		9
embryonic S3		11
leg disc CME L1		5
wing disc CME-W2		7
wing disc ML-DmD8		8
wing disc ML-DmD9		6
wing disc ML-DmD16-c3		7
wing disc ML-DmD21		12
wing disc ML-DmD32		8
haltere disc ML-DmD17-c3		13
eye-antennal disc ML-DmD11		7
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		6
CNS ML-DmBG1-c1		9
CNS ML-DmBG2-c2		11
tumorous blood cells mbn2		7
ovary fGS/OSS		8
ovary OSC		5
ovary OSS		5
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		9
Schneider line 2 Sg4		7
embryonic 1182-4H		7
embryonic GM2		7
embryonic Kc167		11
embryonic S1		9
embryonic S3		11
leg disc CME L1		5
wing disc CME-W2		7
wing disc ML-DmD8		8
wing disc ML-DmD9		6
wing disc ML-DmD16-c3		7
wing disc ML-DmD21		12
wing disc ML-DmD32		8
haltere disc ML-DmD17-c3		13
eye-antennal disc ML-DmD11		7
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		6
CNS ML-DmBG1-c1		9
CNS ML-DmBG2-c2		11
tumorous blood cells mbn2		7
ovary fGS/OSS		8
ovary OSC		5
ovary OSS		5
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		3
cold shock, 4-day adult		2
heat shock, 4-day adult		5
Cadmium 50 mM 6 hrs, larvae L3		5
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		4
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		2
Copper 15 mM 48 hrs, 4-day adult		4
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		9
Ethanol 5% 3 hrs, larvae L3		3
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		8
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		8
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		4
Rotenone 8 μg 12 hrs, larvae L3		5
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		3
cold shock, 4-day adult		2
heat shock, 4-day adult		5
Cadmium 50 mM 6 hrs, larvae L3		5
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		4
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		2
Copper 15 mM 48 hrs, 4-day adult		4
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		9
Ethanol 5% 3 hrs, larvae L3		3
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		8
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		8
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		4
Rotenone 8 μg 12 hrs, larvae L3		5
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		3
cold shock, 4-day adult		2
heat shock, 4-day adult		5
Cadmium 50 mM 6 hrs, larvae L3		5
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		4
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		2
Copper 15 mM 48 hrs, 4-day adult		4
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		9
Ethanol 5% 3 hrs, larvae L3		3
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		8
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		8
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		4
Rotenone 8 μg 12 hrs, larvae L3		5
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		3
cold shock, 4-day adult		2
heat shock, 4-day adult		5
Cadmium 50 mM 6 hrs, larvae L3		5
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		4
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		2
Copper 15 mM 48 hrs, 4-day adult		4
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		9
Ethanol 5% 3 hrs, larvae L3		3
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		8
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		8
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		4
Rotenone 8 μg 12 hrs, larvae L3		5
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		3
cold shock, 4-day adult		2
heat shock, 4-day adult		5
Cadmium 50 mM 6 hrs, larvae L3		5
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		4
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		2
Copper 15 mM 48 hrs, 4-day adult		4
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		9
Ethanol 5% 3 hrs, larvae L3		3
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		8
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		8
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		4
Rotenone 8 μg 12 hrs, larvae L3		5
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		3
cold shock, 4-day adult		2
heat shock, 4-day adult		5
Cadmium 50 mM 6 hrs, larvae L3		5
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		4
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		2
Copper 15 mM 48 hrs, 4-day adult		4
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		9
Ethanol 5% 3 hrs, larvae L3		3
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		8
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		8
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		4
Rotenone 8 μg 12 hrs, larvae L3		5
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		3
cold shock, 4-day adult		2
heat shock, 4-day adult		5
Cadmium 50 mM 6 hrs, larvae L3		5
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		4
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		2
Copper 15 mM 48 hrs, 4-day adult		4
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		9
Ethanol 5% 3 hrs, larvae L3		3
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		8
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		8
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		4
Rotenone 8 μg 12 hrs, larvae L3		5
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		3
cold shock, 4-day adult		2
heat shock, 4-day adult		5
Cadmium 50 mM 6 hrs, larvae L3		5
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		4
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		2
Copper 15 mM 48 hrs, 4-day adult		4
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		9
Ethanol 5% 3 hrs, larvae L3		3
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		8
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		8
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		4
Rotenone 8 μg 12 hrs, larvae L3		5
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

BDGP expression data

•

LD08328

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0037656

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG11986-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable

CG11986^EY16734

viable, with Scer\GAL4^pnr-MD237

CG11986^GD7453

Sterility

Allele

fertile

CG11986^EY16734

Phenotype manifest in

Allele

Classical Alleles ( 1 )

For All Classical Alleles Show

Allele of CG11986	Class	Mutagen	Stocks	Known lesion
CG11986^EY16734		P-element activity	1	--

Alleles Carried on Transgenic Constructs ( 3 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG11986	Mutagen	Stocks	Known lesion
CG11986^GD7453	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG11986^KK100310	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG11986^NIG.11986R	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Disrupted in

Df(3R)Exel6258

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD7453}

P{KK100310}

P{NIG.11986R}

Insertions

Type of insertions

Name

Expression data

insertion of mobile activating element

P{EPgy2}CG11986^EY16734

Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 0 terms )

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG11986 allele

Gene

References

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0037656

Orthologs

OrthoDB Orthologs (32) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG6B2TH9

Dipteran inclusive ortholog search

EOG6Q2DQB

Insect inclusive ortholog search

EOG6SN0JG

Arthropod inclusive ortholog search

EOG65HQD3

Metazoa inclusive ortholog search

EOG6FZ42F

Orthologs in Drosophila Species (EOG6B2TH9)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA11312

Drosophila persimilis

Dper\GL12116

Drosophila willistoni

Dwil\GK11678

Drosophila virilis

Dvir\GJ10305

Drosophila mojavensis

Dmoj\GI22584

Drosophila grimshawi

Dgri\GH19381

Orthologs in non-Drosophila Dipterans (EOG6Q2DQB)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL000411

Anopheles gambiae

Malaria mosquito

Agam\AGAP003544

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ007469

Orthologs in non-Dipteran Insects (EOG6SN0JG)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\LOC408900

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG013334

Atta cephalotes

Leafcutter ant

Acep\ACEP13527

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO17009

Linepithema humile

Argentine ant

Lhum\LH10127

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB10375

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI004631

Pediculus humanus

Human body louse

Phum\PHUM106450

Orthologs in non-Insect Arthropods (EOG65HQD3)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Daphnia pulex

Water flea

Dpux\Eml1

Ixodes scapularis

Deer tick

Isca\ISCW013677

Orthologs in non-Arthropod Metazoa (EOG6FZ42F)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_012777gn

Danio rerio

Zebrafish

Drer\zgc:165500

Xenopus tropicalis

Western clawed frog

Xtro\ENSXETG00000024746

Gallus gallus

Domestic chicken

Ggal\C12H3orf37

Mus musculus

House mouse

Mmus\ENSMUSG00000030060

Rattus norvegicus

Norway rat

Rnor\LOC500251

Homo sapiens

Human

Hsap\C3orf37

Human Orthologs (1)

Gene

OMIM

HGNC

Hsap\C3orf37

AAA Orthologs (11) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA11312

Drosophila persimilis

Dper\GL12116

Drosophila willistoni

Dwil\GK11678

Drosophila virilis

Dvir\GJ10305

Drosophila mojavensis

Dmoj\GI22584

Drosophila grimshawi

Dgri\GH19381

Stocks & Reagents

Stocks Listed in FlyBase ( 3 )

Bloomington

21232

y¹ w^67c23; P{EPgy2}CG11986^EY16734

VDRC

v106970

P{KK100310}VIE-260B

v20136

w¹¹¹⁸; P{GD7453}v20136

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 6 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

LD08328

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

bs27g07

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0037656

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

41083

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_141605

RefSeq (Proteins)

•

NP_649862

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

41083

UniProtKB/TrEMBL

•

Q9VHI3

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Protein of unknown function DUF159 (IPR003738)

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

•

LD08328

Linkouts

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0037656

DRSC - Results from RNAi screens.

•

FBgn0037656

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0037656

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG11986-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0037656

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

41083

modMine - Data generated by the modENCODE project.

•

FBgn0037656

Synonyms & Secondary IDs ( 1 )

Reported As

Symbol Synonym

CG11986

(Weiler, 2007, Keleman et al., 2009.8.5, Japanese National Institute of Genetics, 2012.5.21)

Name Synonym

Secondary FlyBase IDs

References ( 12 )

Research paper

Weiler, 2007, Genetics 177(1): 167--178: E(var)3-9 of Drosophila melanogaster Encodes a Zinc Finger Protein. [FBrf0201244]

Supplementary material

Graveley et al., 2011, Nature 471(7339):: Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980]
The modENCODE Consortium, 2010, Science 330(6012):: DataS14: Gene co-expression clusters. [FBrf0213979]
Mummery-Widmer et al., 2009, Nature 458(7241):: Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]

Personal communication to FlyBase

Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510]
Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
Ryder, 2004.4.26, Exelixis CG deletion data.: Exelixis CG deletion data. [FBrf0184335]
Gene Disruption Project members, 2001-, (Computer file): (Computer file) [FBrf0132177]
Oliver, 2001.8.16, Genome Res.:: File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). [FBrf0137492]
BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file): Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]

Stock list

Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY.: RNAi stocks available from NIG-FLY. [FBrf0218457]