• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\Kdm2

General Information
Symbol	Dmel\Kdm2	Species	D. melanogaster
Name	Lysine (K)-specific demethylase 2	Annotation symbol	CG11033
Feature type	protein_coding_gene	FlyBase ID	FBgn0037659
Gene Model Status	Current	Stock availability	24 publicly available
Also Known As	dkdm2
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	85C3-85C4	Sequence location	3R:4,878,217..4,888,967 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Lysine (K)-specific demethylase 2 is referred to in FlyBase by the symbol Dmel\Kdm2 (CG11033, FBgn0037659). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: histone demethylase activity (H3-trimethyl-K4 specific). There is experimental evidence that it is involved in the biological process: segment specification; histone H3-K36 demethylation; histone H3-K4 demethylation, trimethyl-H3-K4-specific; histone H2A ubiquitination. 34 alleles are reported. The phenotype of these alleles is annotated with: nucleolus. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: F-box domain, cyclin-like; JmjC domain; Leucine-rich repeat, cysteine-containing subtype; Zinc finger, CXXC-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1634555_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG11033. Gene sequence location is 3R:4878217..4888967.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03	Alleles Kdm2[C774] Kdm2[EP3093]
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 85C3-85C4   Limits computationally determined from genome sequence between P{lacW}l(3)L4740L4740 and P{EP}D1EP473
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Kdm2 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.48
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Kdm2-RB FBtr0300691  NM_141607   5304   1345 Kdm2-RC FBtr0336758  NM_001275471   5252   1345 Kdm2-RD FBtr0336759  NM_001275472   5289   1345 Kdm2-RE FBtr0336760  NM_001275473   5356   1345
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Kdm2-PB   FBpp0289915   146.2   1345   8.67     NP_649864   AAF54335 Kdm2-PC   FBpp0307734   146.2   1345   8.67     NP_001262400   AGB95782 Kdm2-PD   FBpp0307735   146.2   1345   8.67     NP_001262401   AGB95783 Kdm2-PE   FBpp0307736   146.2   1345   8.67     NP_001262402   AGB95784
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • F-box domain, cyclin-like (IPR001810) Zinc finger, CXXC-type (IPR002857) JmjC domain (IPR003347) Leucine-rich repeat, cysteine-containing subtype (IPR006553)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF54335   AE014297 AGB95782   AE014297 AGB95783   AE014297 AGB95784   AI531200   AI531277   AI532608   AQ073128   AQ073160   AQ073810   AQ073860   AQ073975   AW944347   BG639534   BH759444   BP547816   BT009941 AAQ22410   CK661663   CO155840   CO180749   CO186306   CO262887   CO272599   CO273061   CO274022   CO294830   CO304075   CO309002   CO311185   CO324072   CO343485   CZ472453   CZ473072   CZ474876   CZ474952   CZ475308   CZ475482   CZ485381   CZ485382   EC064125   EC077006   EC078332   EC079999   EC083292   EC196735   EC213522   EC231131   EC232569   EC236727   EC246695   EC260593   EC260609   EC265721   GH766932   GH942648   GH943598   GH944066   GH944656   GH945662   GH945883   GH947952   GH949182   GH954103   GH956675   GH962184   GH963966   GH964860   GH965437   GH968452   GH968573   GH969625   GH977512   GH979057   GH979532   GH982343
UniProtKB/Swiss-Prot	Q9VHH9
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References regulatory region FBsf0000435860 3R:4,882,660..4,883,235 evidence=Reporter construct (in vivo) (Junion et al., 2012, Halfon, 2012.6.19)
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 5 of adulthood & male -- day 7 of adulthood & male   spermatozoon   (Dorus et al., 2006)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
PcG protein complex inferred from physical interaction with Sce, Psc (Lagarou et al., 2008)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    384.7 Larval Midgut    69.4 Larval Hindgut    121.7 Larval Malpighian Tubules    119 Larval Fat Body    89.4 Larval Salivary Gland    138.7 Larval Trachea    183.95 Larval Carcass    110.425 Adult Head    157.2 Adult Eye    126.975 Adult Brain    348.9 Adult Thoracic-Abdominal Ganglion    262.4 Adult Crop    176.9 Adult Midgut    69.9 Adult Hindgut    129.2 Adult Malpighian Tubules    163.2 Adult Fat Body    84.9 Adult Salivary Gland    113.5 Adult Heart    84.45 Adult VirginFemale Spermatheca    112.3 Adult InseminatedFemale Spermatheca    123.6 Adult Ovary    274 Adult Testis    38.6 Adult Male Accessory Gland    113.8 Adult Carcass    108.6 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    384.7 Larval Midgut    69.4 Larval Hindgut    121.7 Larval Malpighian Tubules    119 Larval Fat Body    89.4 Larval Salivary Gland    138.7 Larval Trachea    183.95 Larval Carcass    110.425 Adult Head    157.2 Adult Eye    126.975 Adult Brain    348.9 Adult Thoracic-Abdominal Ganglion    262.4 Adult Crop    176.9 Adult Midgut    69.9 Adult Hindgut    129.2 Adult Malpighian Tubules    163.2 Adult Fat Body    84.9 Adult Salivary Gland    113.5 Adult Heart    84.45 Adult VirginFemale Spermatheca    112.3 Adult InseminatedFemale Spermatheca    123.6 Adult Ovary    274 Adult Testis    38.6 Adult Male Accessory Gland    113.8 Adult Carcass    108.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    384.7 Larval Midgut    69.4 Larval Hindgut    121.7 Larval Malpighian Tubules    119 Larval Fat Body    89.4 Larval Salivary Gland    138.7 Larval Trachea    183.95 Larval Carcass    110.425 Adult Head    157.2 Adult Eye    126.975 Adult Brain    348.9 Adult Thoracic-Abdominal Ganglion    262.4 Adult Crop    176.9 Adult Midgut    69.9 Adult Hindgut    129.2 Adult Malpighian Tubules    163.2 Adult Fat Body    84.9 Adult Salivary Gland    113.5 Adult Heart    84.45 Adult VirginFemale Spermatheca    112.3 Adult InseminatedFemale Spermatheca    123.6 Adult Ovary    274 Adult Testis    38.6 Adult Male Accessory Gland    113.8 Adult Carcass    108.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    384.7 Larval Midgut    69.4 Larval Hindgut    121.7 Larval Malpighian Tubules    119 Larval Fat Body    89.4 Larval Salivary Gland    138.7 Larval Trachea    183.95 Larval Carcass    110.425 Adult Head    157.2 Adult Eye    126.975 Adult Brain    348.9 Adult Thoracic-Abdominal Ganglion    262.4 Adult Crop    176.9 Adult Midgut    69.9 Adult Hindgut    129.2 Adult Malpighian Tubules    163.2 Adult Fat Body    84.9 Adult Salivary Gland    113.5 Adult Heart    84.45 Adult VirginFemale Spermatheca    112.3 Adult InseminatedFemale Spermatheca    123.6 Adult Ovary    274 Adult Testis    38.6 Adult Male Accessory Gland    113.8 Adult Carcass    108.6 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    384.7 Larval Midgut    69.4 Larval Hindgut    121.7 Larval Malpighian Tubules    119 Larval Fat Body    89.4 Larval Salivary Gland    138.7 Larval Trachea    183.95 Larval Carcass    110.425 Adult Head    157.2 Adult Eye    126.975 Adult Brain    348.9 Adult Thoracic-Abdominal Ganglion    262.4 Adult Crop    176.9 Adult Midgut    69.9 Adult Hindgut    129.2 Adult Malpighian Tubules    163.2 Adult Fat Body    84.9 Adult Salivary Gland    113.5 Adult Heart    84.45 Adult VirginFemale Spermatheca    112.3 Adult InseminatedFemale Spermatheca    123.6 Adult Ovary    274 Adult Testis    38.6 Adult Male Accessory Gland    113.8 Adult Carcass    108.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    384.7 Larval Midgut    69.4 Larval Hindgut    121.7 Larval Malpighian Tubules    119 Larval Fat Body    89.4 Larval Salivary Gland    138.7 Larval Trachea    183.95 Larval Carcass    110.425 Adult Head    157.2 Adult Eye    126.975 Adult Brain    348.9 Adult Thoracic-Abdominal Ganglion    262.4 Adult Crop    176.9 Adult Midgut    69.9 Adult Hindgut    129.2 Adult Malpighian Tubules    163.2 Adult Fat Body    84.9 Adult Salivary Gland    113.5 Adult Heart    84.45 Adult VirginFemale Spermatheca    112.3 Adult InseminatedFemale Spermatheca    123.6 Adult Ovary    274 Adult Testis    38.6 Adult Male Accessory Gland    113.8 Adult Carcass    108.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    384.7 Larval Midgut    69.4 Larval Hindgut    121.7 Larval Malpighian Tubules    119 Larval Fat Body    89.4 Larval Salivary Gland    138.7 Larval Trachea    183.95 Larval Carcass    110.425 Adult Head    157.2 Adult Eye    126.975 Adult Brain    348.9 Adult Thoracic-Abdominal Ganglion    262.4 Adult Crop    176.9 Adult Midgut    69.9 Adult Hindgut    129.2 Adult Malpighian Tubules    163.2 Adult Fat Body    84.9 Adult Salivary Gland    113.5 Adult Heart    84.45 Adult VirginFemale Spermatheca    112.3 Adult InseminatedFemale Spermatheca    123.6 Adult Ovary    274 Adult Testis    38.6 Adult Male Accessory Gland    113.8 Adult Carcass    108.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    384.7 Larval Midgut    69.4 Larval Hindgut    121.7 Larval Malpighian Tubules    119 Larval Fat Body    89.4 Larval Salivary Gland    138.7 Larval Trachea    183.95 Larval Carcass    110.425 Adult Head    157.2 Adult Eye    126.975 Adult Brain    348.9 Adult Thoracic-Abdominal Ganglion    262.4 Adult Crop    176.9 Adult Midgut    69.9 Adult Hindgut    129.2 Adult Malpighian Tubules    163.2 Adult Fat Body    84.9 Adult Salivary Gland    113.5 Adult Heart    84.45 Adult VirginFemale Spermatheca    112.3 Adult InseminatedFemale Spermatheca    123.6 Adult Ovary    274 Adult Testis    38.6 Adult Male Accessory Gland    113.8 Adult Carcass    108.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    157.2   NA  Eye    126.975   NA  Brain    348.9   384.7  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    262.4   NA  Crop    176.9   69.4  Midgut    no informative data   121.7  Hindgut    129.2   119  Malpighian Tubules    163.2   89.4  Fat Body    84.9   138.7  Salivary Gland    113.5   NA  Heart    84.45   183.95  Trachea    NA   NA  VirginFemale Spermatheca    112.3   NA  InseminatedFemale Spermatheca    123.6   NA  Ovary    274   NA  Testis    38.6   NA  Male Accessory Gland    113.8   110.425  Carcass    108.6 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    29 central nervous system, pupae P8    21 head, virgin 1-day female    10 head, virgin 4-day female    11 head, virgin 20-day female    10 head, mated 1-day female    8 head, mated 4-day female    11 head, mated 20-day female    8 head, mated 1-day male    13 head, mated 4-day male    16 head, mated 20-day male    20 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    3 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    5 fat body, pupae P8    9 carcass, larvae L3 wandering    15 carcass, 1-day adult    5 carcass, 4-day adult    6 carcass, 20-day adult    6 ovary, virgin 4-day female    21 ovary, mated 4-day female    21 testis, mated 4-day male    4 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3  (29) central nervous system, pupae P8    21 head, virgin 1-day female    10 head, virgin 4-day female    11 head, virgin 20-day female    10 head, mated 1-day female    8 head, mated 4-day female    11 head, mated 20-day female    8 head, mated 1-day male    13 head, mated 4-day male    16 head, mated 20-day male    20 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    3 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    5 fat body, pupae P8    9 carcass, larvae L3 wandering    15 carcass, 1-day adult    5 carcass, 4-day adult    6 carcass, 20-day adult    6 ovary, virgin 4-day female    21 ovary, mated 4-day female    21 testis, mated 4-day male    4 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    29 central nervous system, pupae P8    21 head, virgin 1-day female    10 head, virgin 4-day female    11 head, virgin 20-day female    10 head, mated 1-day female    8 head, mated 4-day female    11 head, mated 20-day female    8 head, mated 1-day male    13 head, mated 4-day male    16 head, mated 20-day male    20 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    3 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    5 fat body, pupae P8    9 carcass, larvae L3 wandering    15 carcass, 1-day adult    5 carcass, 4-day adult    6 carcass, 20-day adult    6 ovary, virgin 4-day female    21 ovary, mated 4-day female    21 testis, mated 4-day male    4 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    29 central nervous system, pupae P8    21 head, virgin 1-day female    10 head, virgin 4-day female    11 head, virgin 20-day female    10 head, mated 1-day female    8 head, mated 4-day female    11 head, mated 20-day female    8 head, mated 1-day male    13 head, mated 4-day male    16 head, mated 20-day male    20 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    3 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    5 fat body, pupae P8    9 carcass, larvae L3 wandering    15 carcass, 1-day adult    5 carcass, 4-day adult    6 carcass, 20-day adult    6 ovary, virgin 4-day female    21 ovary, mated 4-day female    21 testis, mated 4-day male    4 accessory gland, mated 4-day male    5 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    29 central nervous system, pupae P8    21 head, virgin 1-day female    10 head, virgin 4-day female    11 head, virgin 20-day female    10 head, mated 1-day female    8 head, mated 4-day female    11 head, mated 20-day female    8 head, mated 1-day male    13 head, mated 4-day male    16 head, mated 20-day male    20 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    3 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    5 fat body, pupae P8    9 carcass, larvae L3 wandering    15 carcass, 1-day adult    5 carcass, 4-day adult    6 carcass, 20-day adult    6 ovary, virgin 4-day female    21 ovary, mated 4-day female    21 testis, mated 4-day male    4 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3  29 central nervous system, pupae P8    21 head, virgin 1-day female    10 head, virgin 4-day female    11 head, virgin 20-day female    10 head, mated 1-day female    8 head, mated 4-day female    11 head, mated 20-day female    8 head, mated 1-day male    13 head, mated 4-day male    16 head, mated 20-day male    20 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    3 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    5 fat body, pupae P8    9 carcass, larvae L3 wandering    15 carcass, 1-day adult    5 carcass, 4-day adult    6 carcass, 20-day adult    6 ovary, virgin 4-day female    21 ovary, mated 4-day female    21 testis, mated 4-day male    4 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    29 central nervous system, pupae P8    21 head, virgin 1-day female    10 head, virgin 4-day female    11 head, virgin 20-day female    10 head, mated 1-day female    8 head, mated 4-day female    11 head, mated 20-day female    8 head, mated 1-day male    13 head, mated 4-day male    16 head, mated 20-day male    20 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    3 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    5 fat body, pupae P8    9 carcass, larvae L3 wandering    15 carcass, 1-day adult    5 carcass, 4-day adult    6 carcass, 20-day adult    6 ovary, virgin 4-day female    21 ovary, mated 4-day female    21 testis, mated 4-day male    4 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    29 central nervous system, pupae P8    21 head, virgin 1-day female    10 head, virgin 4-day female    11 head, virgin 20-day female    10 head, mated 1-day female    8 head, mated 4-day female    11 head, mated 20-day female    8 head, mated 1-day male    13 head, mated 4-day male    16 head, mated 20-day male    20 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    3 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    5 fat body, pupae P8    9 carcass, larvae L3 wandering    15 carcass, 1-day adult    5 carcass, 4-day adult    6 carcass, 20-day adult    6 ovary, virgin 4-day female    21 ovary, mated 4-day female    21 testis, mated 4-day male    4 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, during early pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    12 embryo 04-06hr    22 embryo 06-08hr    27 embryo 08-10hr    29 embryo 10-12hr    24 embryo 12-14hr    22 embryo 14-16hr    19 embryo 16-18hr    12 embryo 18-20hr    9 embryo 20-22hr    13 embryo 22-24hr    13 larva L1    14 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    11 white prepupae new    11 white prepupae 12hr    18 white prepupae 24hr    25 pupae 2d postWPP    14 pupae 3d postWPP    8 pupae 4d postWPP    9 adult male 01day    7 adult male 05day    9 adult male 30day    9 adult female 01day    12 adult female 05day    14 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    12 embryo 04-06hr    22 embryo 06-08hr  (27) embryo 08-10hr  (29) embryo 10-12hr    24 embryo 12-14hr    22 embryo 14-16hr    19 embryo 16-18hr    12 embryo 18-20hr    9 embryo 20-22hr    13 embryo 22-24hr    13 larva L1    14 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    11 white prepupae new    11 white prepupae 12hr    18 white prepupae 24hr    25 pupae 2d postWPP    14 pupae 3d postWPP    8 pupae 4d postWPP    9 adult male 01day    7 adult male 05day    9 adult male 30day    9 adult female 01day    12 adult female 05day    14 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    12 embryo 04-06hr    22 embryo 06-08hr    27 embryo 08-10hr    29 embryo 10-12hr    24 embryo 12-14hr    22 embryo 14-16hr    19 embryo 16-18hr    12 embryo 18-20hr    9 embryo 20-22hr    13 embryo 22-24hr    13 larva L1    14 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    11 white prepupae new    11 white prepupae 12hr    18 white prepupae 24hr    25 pupae 2d postWPP    14 pupae 3d postWPP    8 pupae 4d postWPP    9 adult male 01day    7 adult male 05day    9 adult male 30day    9 adult female 01day    12 adult female 05day    14 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    12 embryo 04-06hr    22 embryo 06-08hr    27 embryo 08-10hr    29 embryo 10-12hr    24 embryo 12-14hr    22 embryo 14-16hr    19 embryo 16-18hr    12 embryo 18-20hr    9 embryo 20-22hr    13 embryo 22-24hr    13 larva L1    14 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    11 white prepupae new    11 white prepupae 12hr    18 white prepupae 24hr    25 pupae 2d postWPP    14 pupae 3d postWPP    8 pupae 4d postWPP    9 adult male 01day    7 adult male 05day    9 adult male 30day    9 adult female 01day    12 adult female 05day    14 adult female 30day    14 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    12 embryo 04-06hr    22 embryo 06-08hr    27 embryo 08-10hr    29 embryo 10-12hr    24 embryo 12-14hr    22 embryo 14-16hr    19 embryo 16-18hr    12 embryo 18-20hr    9 embryo 20-22hr    13 embryo 22-24hr    13 larva L1    14 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    11 white prepupae new    11 white prepupae 12hr    18 white prepupae 24hr    25 pupae 2d postWPP    14 pupae 3d postWPP    8 pupae 4d postWPP    9 adult male 01day    7 adult male 05day    9 adult male 30day    9 adult female 01day    12 adult female 05day    14 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    12 embryo 04-06hr    22 embryo 06-08hr  27 embryo 08-10hr  29 embryo 10-12hr    24 embryo 12-14hr    22 embryo 14-16hr    19 embryo 16-18hr    12 embryo 18-20hr    9 embryo 20-22hr    13 embryo 22-24hr    13 larva L1    14 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    11 white prepupae new    11 white prepupae 12hr    18 white prepupae 24hr    25 pupae 2d postWPP    14 pupae 3d postWPP    8 pupae 4d postWPP    9 adult male 01day    7 adult male 05day    9 adult male 30day    9 adult female 01day    12 adult female 05day    14 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    12 embryo 04-06hr    22 embryo 06-08hr    27 embryo 08-10hr    29 embryo 10-12hr    24 embryo 12-14hr    22 embryo 14-16hr    19 embryo 16-18hr    12 embryo 18-20hr    9 embryo 20-22hr    13 embryo 22-24hr    13 larva L1    14 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    11 white prepupae new    11 white prepupae 12hr    18 white prepupae 24hr    25 pupae 2d postWPP    14 pupae 3d postWPP    8 pupae 4d postWPP    9 adult male 01day    7 adult male 05day    9 adult male 30day    9 adult female 01day    12 adult female 05day    14 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    12 embryo 04-06hr    22 embryo 06-08hr    27 embryo 08-10hr    29 embryo 10-12hr    24 embryo 12-14hr    22 embryo 14-16hr    19 embryo 16-18hr    12 embryo 18-20hr    9 embryo 20-22hr    13 embryo 22-24hr    13 larva L1    14 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    11 white prepupae new    11 white prepupae 12hr    18 white prepupae 24hr    25 pupae 2d postWPP    14 pupae 3d postWPP    8 pupae 4d postWPP    9 adult male 01day    7 adult male 05day    9 adult male 30day    9 adult female 01day    12 adult female 05day    14 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    33 Schneider line 2 Sg4    23 embryonic 1182-4H    26 embryonic GM2    34 embryonic Kc167    23 embryonic S1    36 embryonic S3    26 leg disc CME L1    26 wing disc CME-W2    18 wing disc ML-DmD8    22 wing disc ML-DmD9    42 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    14 wing disc ML-DmD32    22 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    24 antennal disc ML-DmD20-c5    14 mixed discs ML-DmD4-c1    24 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    22 tumorous blood cells mbn2    19 ovary fGS/OSS    26 ovary OSC    14 ovary OSS    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (33) Schneider line 2 Sg4    23 embryonic 1182-4H  26 embryonic GM2  (34) embryonic Kc167    23 embryonic S1  (36) embryonic S3  26 leg disc CME L1  26 wing disc CME-W2    18 wing disc ML-DmD8    22 wing disc ML-DmD9  (42) wing disc ML-DmD16-c3    20 wing disc ML-DmD21    14 wing disc ML-DmD32    22 haltere disc ML-DmD17-c3  (34) eye-antennal disc ML-DmD11    24 antennal disc ML-DmD20-c5    14 mixed discs ML-DmD4-c1    24 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    22 tumorous blood cells mbn2    19 ovary fGS/OSS  26 ovary OSC    14 ovary OSS    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    33 Schneider line 2 Sg4    23 embryonic 1182-4H    26 embryonic GM2    34 embryonic Kc167    23 embryonic S1    36 embryonic S3    26 leg disc CME L1    26 wing disc CME-W2    18 wing disc ML-DmD8    22 wing disc ML-DmD9    42 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    14 wing disc ML-DmD32    22 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    24 antennal disc ML-DmD20-c5    14 mixed discs ML-DmD4-c1    24 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    22 tumorous blood cells mbn2    19 ovary fGS/OSS    26 ovary OSC    14 ovary OSS    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    33 Schneider line 2 Sg4    23 embryonic 1182-4H    26 embryonic GM2    34 embryonic Kc167    23 embryonic S1    36 embryonic S3    26 leg disc CME L1    26 wing disc CME-W2    18 wing disc ML-DmD8    22 wing disc ML-DmD9    42 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    14 wing disc ML-DmD32    22 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    24 antennal disc ML-DmD20-c5    14 mixed discs ML-DmD4-c1    24 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    22 tumorous blood cells mbn2    19 ovary fGS/OSS    26 ovary OSC    14 ovary OSS    14 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    33 Schneider line 2 Sg4    23 embryonic 1182-4H    26 embryonic GM2    34 embryonic Kc167    23 embryonic S1    36 embryonic S3    26 leg disc CME L1    26 wing disc CME-W2    18 wing disc ML-DmD8    22 wing disc ML-DmD9    42 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    14 wing disc ML-DmD32    22 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    24 antennal disc ML-DmD20-c5    14 mixed discs ML-DmD4-c1    24 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    22 tumorous blood cells mbn2    19 ovary fGS/OSS    26 ovary OSC    14 ovary OSS    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (33) Schneider line 2 Sg4    23 embryonic 1182-4H  26 embryonic GM2  (34) embryonic Kc167    23 embryonic S1  (36) embryonic S3  26 leg disc CME L1  26 wing disc CME-W2    18 wing disc ML-DmD8    22 wing disc ML-DmD9  (42) wing disc ML-DmD16-c3    20 wing disc ML-DmD21    14 wing disc ML-DmD32    22 haltere disc ML-DmD17-c3  (34) eye-antennal disc ML-DmD11    24 antennal disc ML-DmD20-c5    14 mixed discs ML-DmD4-c1    24 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    22 tumorous blood cells mbn2    19 ovary fGS/OSS  26 ovary OSC    14 ovary OSS    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    33 Schneider line 2 Sg4    23 embryonic 1182-4H    26 embryonic GM2    34 embryonic Kc167    23 embryonic S1    36 embryonic S3    26 leg disc CME L1    26 wing disc CME-W2    18 wing disc ML-DmD8    22 wing disc ML-DmD9    42 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    14 wing disc ML-DmD32    22 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    24 antennal disc ML-DmD20-c5    14 mixed discs ML-DmD4-c1    24 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    22 tumorous blood cells mbn2    19 ovary fGS/OSS    26 ovary OSC    14 ovary OSS    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    33 Schneider line 2 Sg4    23 embryonic 1182-4H    26 embryonic GM2    34 embryonic Kc167    23 embryonic S1    36 embryonic S3    26 leg disc CME L1    26 wing disc CME-W2    18 wing disc ML-DmD8    22 wing disc ML-DmD9    42 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    14 wing disc ML-DmD32    22 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    24 antennal disc ML-DmD20-c5    14 mixed discs ML-DmD4-c1    24 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    22 tumorous blood cells mbn2    19 ovary fGS/OSS    26 ovary OSC    14 ovary OSS    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    7 heat shock, 4-day adult    12 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    10 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    19 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    7 heat shock, 4-day adult    12 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    10 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    19 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    7 heat shock, 4-day adult    12 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    10 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    19 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    7 heat shock, 4-day adult    12 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    10 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    19 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    7 heat shock, 4-day adult    12 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    10 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    19 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    7 heat shock, 4-day adult    12 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    10 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    19 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    7 heat shock, 4-day adult    12 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    10 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    19 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    7 heat shock, 4-day adult    12 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    10 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    19 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_30 mE1_20_mRNA_expression_cluster_04
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037659 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11033-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal Kdm2DG12810 Kdm2KG04325 partially lethal - majority die | recessive Kdm2DG12810 viable Kdm2EY01336 viable, with Scer\GAL4pnr-MD237 Kdm2GD7173 Phenotype manifest in Allele nucleolus, with Scer\GAL4Act5C.PU Kdm2GD7173
Classical Alleles ( 32 )
For All Classical Alleles Show
Allele of Kdm2 Class Mutagen Stocks Known lesion Kdm236Y P-element activity 1 Yes Kdm25-HA-1597 1 -- Kdm25-HA-1652 1 -- Kdm25-SZ-3704 1 -- Kdm2CB-0139-3 1 -- Kdm2CB-5469-3 1 -- Kdm2CB-6292-3 1 -- Kdm2CB-6663-3 1 -- Kdm2d00170 1 -- Kdm2d02926 P-element activity 1 -- Kdm2d06162 P-element activity 1 -- Kdm2d06730 P-element activity 1 -- Kdm2EP3093 1 -- Kdm2EY01336 P-element activity 1 -- Kdm2f02665 1 -- Kdm2f02828 piggyBac transposase 1 -- Kdm2F11.1 1 -- Kdm2KG04325 P-element activity 1 -- Kdm2NP0554 1 -- Kdm2NP2159 1 -- Kdm2NP2572 1 -- Kdm25-HA-1066 0 -- Kdm2C774 0 -- Kdm2d01804 P-element activity 0 -- Kdm2d06019 P-element activity 0 -- Kdm2d07005 P-element activity 0 -- Kdm2DG12810 P-element activity 0 -- Kdm2EP3198 P-element activity 0 -- Kdm2EP3256 P-element activity 0 -- Kdm2EP3396 P-element activity 0 -- Kdm2EP3699 P-element activity 0 -- Kdm2EP3737 P-element activity 0 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Kdm2 Class Mutagen Stocks Known lesion Kdm2GD7173 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Kdm2HMS00574 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Kdm2JF01320 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Kdm2KK101783 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{KK101783} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}EP1096 NA P{EP}EP3471 NA P{EP}Kdm2EP3093 NA P{EP}Kdm2EP3198 NA P{EP}Kdm2EP3256 NA P{EP}Kdm2EP3396 NA P{EP}Kdm2EP3699 NA P{EP}Kdm2EP3737 NA P{EPgy2}Kdm2EY01336 NA P{XP}Kdm2d00170 NA P{XP}Kdm2d01804 NA P{XP}Kdm2d02926 NA P{XP}Kdm2d06019 NA P{XP}Kdm2d06162 NA P{XP}Kdm2d06730 NA P{XP}Kdm2d07005 NA miscellaneous insertions P{ID.GAL4DBD}Kdm2F11.1 NA P{RS3}Kdm2CB-0139-3 NA P{RS3}Kdm2CB-5469-3 NA P{RS3}Kdm2CB-6292-3 NA P{RS3}Kdm2CB-6663-3 NA P{RS5}Kdm25-HA-1066 NA P{RS5}Kdm25-HA-1597 NA P{RS5}Kdm25-HA-1652 NA P{RS5}Kdm25-SZ-3704 NA P{SUPor-P}Kdm2KG04325 NA P{wHy}Kdm2DG12810 NA PBac{WH}Kdm2f02665 NA PBac{WH}Kdm2f02828 NA insertion of enhancer trap binary system P{ET-QF}ET11 No P{GawB}Kdm236Y No P{GawB}Kdm2C774 No P{GawB}Kdm2NP0554 No P{GawB}Kdm2NP2159 No P{GawB}Kdm2NP2572 No
Gene Ontology: Function, Process & Cellular Component ( 8 unique terms )
Terms Based on Experimental Evidence ( 6 terms )
Molecular Function
CV term Evidence References
histone demethylase activity (H3-trimethyl-K4 specific) inferred from mutant phenotype (Kavi and Birchler, 2009)
Biological Process
CV term Evidence References
histone H2A ubiquitination inferred from direct assay (Lagarou et al., 2008) inferred from mutant phenotype (Lagarou et al., 2008) histone H3-K4 demethylation, trimethyl-H3-K4-specific inferred from mutant phenotype (Kavi and Birchler, 2009) histone H3-K36 demethylation inferred from direct assay (Lagarou et al., 2008) inferred from mutant phenotype (Lagarou et al., 2008) segment specification inferred from genetic interaction with ash1 (Lagarou et al., 2008) inferred from genetic interaction with Pc (Lagarou et al., 2008) inferred from genetic interaction with trx (Lagarou et al., 2008)
Cellular Component
CV term Evidence References
PcG protein complex inferred from physical interaction with Sce, Psc (Lagarou et al., 2008)
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
DNA binding inferred from electronic annotation with InterPro:IPR002857 (FlyBase Curators et al., 2004-) zinc ion binding inferred from electronic annotation with InterPro:IPR002857 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Kdm2 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 66257 DroID - A comprehensive database of gene and protein interactions. • FBgn0037659 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41090
Orthologs
OrthoDB Orthologs (29) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6GMVG8 Dipteran inclusive ortholog search EOG6VT657 Insect inclusive ortholog search EOG6JQ2SK Arthropod inclusive ortholog search EOG6KSN0T Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6GMVG8)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Kdm2     Drosophila simulans   Dsim\GD18594     Drosophila sechellia   Dsec\GM23783 Y   Drosophila erecta   Dere\GG14981 Y   Drosophila yakuba   Dyak\GE25927     Drosophila ananassae   Dana\GF16580 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA30197     Drosophila persimilis   Dper\GL22285 Y   Drosophila willistoni   Dwil\GK11583 Y   Drosophila virilis   Dvir\GJ23745 Y   Drosophila mojavensis   Dmoj\GI22556 Y   Drosophila grimshawi   Dgri\GH19346 Y
Orthologs in non-Drosophila Dipterans (EOG6VT657)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL008177   Anopheles gambiae Malaria mosquito  Agam\AGAP001895   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ008371
Orthologs in non-Dipteran Insects (EOG6JQ2SK)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC410848   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG005020   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH20366   Atta cephalotes Leafcutter ant  Acep\ACEP18719   Camponotus floridanus Florida carpenter ant  Cflo\CFLO14245   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL13746   Linepithema humile Argentine ant  Lhum\LH10099   Pogonomyrmex barbatus Red harvester ant  Pbar\PB11568   Acyrthosiphon pisum Pea aphid  Apim\ACYPI010029   Bombyx mori Silkmoth  Bmor\BGIBMGA012843   Pediculus humanus Human body louse  Phum\PHUM316810   Tribolium castaneum Red flour beetle  Tcas\GLEAN_15153
Orthologs in non-Insect Arthropods (EOG6KSN0T)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_308697   Ixodes scapularis Deer tick  Isca\ISCW018631
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (8) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila sechellia Dsec\GM23783 Drosophila erecta Dere\GG14981 Drosophila ananassae Dana\GF16580 Drosophila persimilis Dper\GL22285 Drosophila willistoni Dwil\GK11583 Drosophila virilis Dvir\GJ23745 Drosophila mojavensis Dmoj\GI22556 Drosophila grimshawi Dgri\GH19346
Stocks & Reagents
Stocks Listed in FlyBase ( 24 )
Bloomington	30819 w*; P{GawB}Kdm236Y
Harvard	- P{XP}Kdm2d00170 - P{XP}Kdm2d02926 - P{XP}Kdm2d06162 - P{XP}Kdm2d06730 - PBac{WH}Kdm2f02665 - PBac{WH}Kdm2f02828
Kyoto	123050 w1118; P{RS3}Kdm2CB-0139-3 123641 w1118; P{RS3}Kdm2CB-5469-3 124028 w1118; P{RS3}Kdm2CB-6292-3 124167 w1118; P{RS3}Kdm2CB-6663-3
VDRC	v31402 w1118; P{GD7173}v31402
	More stocks available...
Genomic Clones ( 2 )
	BACR08N17 BACR09F04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 40 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	SD04170
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LP21308 SD02246
Other clones	EC03665 EK018656 EK086640 EK107761 EK109408 EK112920 EK192453 EK207810 EK223715 EK243559 EK259904 EN06832 EP16851 FGH121A05 RP001011210 RP004074636 RP004119671 RP004189097 RP004203323 RP004221667 RP004224102 RP004228399 RP004238233 RP004245250 RP004248992 RP004249385 RP004255361 RP004264459 RP004288830 RP004438481 RP004453915 RP004454954 RP004492051 RP004498500 RP004510012 RP004528148 SD02139
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0037659 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41090
Antibody Information
	polyclonal (Lagarou et al., 2008)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: JHDM1 CG11033 (Lorbeck et al., 2010) Source for identity of: Kdm2 CG11033 (Kavi and Birchler, 2009)
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_141607 NM_001275471 NM_001275472 NM_001275473 RefSeq (Proteins) • NP_649864 NP_001262400 NP_001262401 NP_001262402 DDBJ / EMBL / GenBank • AAF54335 AAQ22410 AGB95782 AGB95783 AGB95784 AI532608 AQ073128 AQ073160 AQ073810 AQ073860 AQ073975 AW944347 BH759444 BT009941 CZ472453 CZ473072 CZ474876 CZ474952 CZ475308 CZ475482 CZ485381 CZ485382 Entrez Gene - A searchable database of RefSeq genes. • 41090 UniProtKB/Swiss-Prot • Q9VHH9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • F-box domain, cyclin-like (IPR001810) Zinc finger, CXXC-type (IPR002857) JmjC domain (IPR003347) Leucine-rich repeat, cysteine-containing subtype (IPR006553)
Linkouts
	BioGRID - A database of protein and genetic interactions • 66257 DroID - A comprehensive database of gene and protein interactions. • FBgn0037659 DRSC - Results from RNAi screens. • FBgn0037659 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037659 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11033-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0037659 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41090 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41090 modMine - Data generated by the modENCODE project. • FBgn0037659
Synonyms & Secondary IDs ( 10 )
Reported As
Symbol Synonym	CG11033 (Gan et al., 2010, Arancio et al., 2010, Curtis et al., 2011, Moran and Kyriacou, 2009, Lagarou et al., 2008, Lorbeck et al., 2010, Klose et al., 2006, Sun et al., 2006, Staudt et al., 2005, Weiler, 2007, Dorus et al., 2006, Bilen and Bonini, 2007, Wu et al., 2007, Potter et al., 2010, Ni et al., 2008, Roberts et al., 2012, Ni et al., 2010.12.1, Kavi and Birchler, 2009, Keleman et al., 2009.8.5, Cunha et al., 2010) dkdm2 (Lagarou et al., 2008) dKDM2 (Kavi and Birchler, 2009, Li et al., 2010, Mohd-Sarip et al., 2012) dRAF1 (Lagarou et al., 2008) FBXL19 (Roberts et al., 2012) JHDM1 (Lorbeck et al., 2010, ) Kdm2 (Devineni et al., 2011, Antao et al., 2012)
Name Synonym	dRING-associated factor 1 (Lagarou et al., 2008) JmjC domain-containing histone demethylase 1   Lysine (K)-specific demethylase 2
Secondary FlyBase IDs
References ( 47 )
Generate a list of	All references relating to this gene ( 47 )
List References by type	Research paper  ( 25 ) Supplementary material  ( 6 ) Review  ( 3 ) Personal communication to FlyBase  ( 11 ) FlyBase analysis  ( 2 )
Recent research papers ( 7 )
	Antao et al., 2012, Mol. Cell. Biol. 32(12): 2170--2182 Protein Landscape at Drosophila melanogaster Telomere-Associated Sequence Repeats. [FBrf0218429] Dui et al., 2012, J. Genet. Genomics 39(8): 397--413 A Systematic Phenotypic Screen of F-box Genes Through a Tissue-specific RNAi-based Approach in Drosophila. [FBrf0219135] Junion et al., 2012, Cell 148(3): 473--486 A transcription factor collective defines cardiac cell fate and reflects lineage history. [FBrf0217404] Mohd-Sarip et al., 2012, Science 336(6082): 744--747 Transcription-independent function of Polycomb group protein PSC in cell cycle control. [FBrf0218404] Roberts et al., 2012, PLoS ONE 7(2): e31284 Defining Components of the ßcatenin Destruction Complex and Exploring Its Regulation and Mechanisms of Action during Development. [FBrf0217546] Curtis et al., 2011, Dev. Biol. 350(2): 534--547 Histone lysine demethylases function as co-repressors of SWI/SNF remodeling activities during Drosophila wing development. [FBrf0212876] Devineni et al., 2011, Fly 5(3): 191--199 The genetic relationships between ethanol preference, acute ethanol sensitivity, and ethanol tolerance in Drosophila melanogaster. [FBrf0214716] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...