General Information Symbol Dmel\ CG8132Species D. melanogaster Name Annotation symbol CG8132 Feature type protein_coding_gene FlyBase ID FBgn0037687 Gene Model Status Current Stock availability 5 publicly
available Genomic Location Chromosome (arm) 3R Recombination map Cytogenetic map 85D15-85D15 Sequence location 3R:5,227,217..5,228,340 [+]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information This gene is referred to in FlyBase by the symbol
Dmel\CG8132 (FBgn0037687). It is a protein_coding_gene from
Drosophila melanogaster . Based on sequence similarity, it is predicted to have
molecular function : nitrilase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the
biological process : nitrogen compound metabolic process.
6 alleles are reported . No phenotypic data is available. It has
one annotated transcript and
one annotated polypeptide .
Protein features are: Carbon-nitrogen hydrolase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during early larval stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult Malpighian tubules. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1641318_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG8132. Gene sequence location is
3R:5227217..5228340 .
User Contributed Data
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FB2013_03
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.49
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: maternally deposited
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
157.075
Larval Midgut
170
Larval Hindgut
179.8
Larval Malpighian Tubules
369.6
Larval Fat Body
432.6
Larval Salivary Gland
160.4
Larval Trachea
210.55
Larval Carcass
131.075
Adult Head
236.3
Adult Eye
168.3
Adult Brain
120.5
Adult Thoracic-Abdominal Ganglion
76.7
Adult Crop
159.2
Adult Midgut
476.6
Adult Hindgut
296.2
Adult Malpighian Tubules
1126.8
Adult Fat Body
487.6
Adult Salivary Gland
195
Adult Heart
435.7
Adult VirginFemale Spermatheca
404.6
Adult InseminatedFemale Spermatheca
426.7
Adult Ovary
185.5
Adult Testis
22.3
Adult Male Accessory Gland
196.3
Adult Carcass
325.6
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
157.075
Larval Midgut
170
Larval Hindgut
179.8
Larval Malpighian Tubules
369.6
Larval Fat Body
432.6
Larval Salivary Gland
160.4
Larval Trachea
210.55
Larval Carcass
131.075
Adult Head
236.3
Adult Eye
168.3
Adult Brain
120.5
Adult Thoracic-Abdominal Ganglion
76.7
Adult Crop
159.2
Adult Midgut
476.6
Adult Hindgut
296.2
Adult Malpighian Tubules
(1126.8)
Adult Fat Body
487.6
Adult Salivary Gland
195
Adult Heart
435.7
Adult VirginFemale Spermatheca
404.6
Adult InseminatedFemale Spermatheca
426.7
Adult Ovary
185.5
Adult Testis
22.3
Adult Male Accessory Gland
196.3
Adult Carcass
325.6
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
157.075
Larval Midgut
170
Larval Hindgut
179.8
Larval Malpighian Tubules
369.6
Larval Fat Body
432.6
Larval Salivary Gland
160.4
Larval Trachea
210.55
Larval Carcass
131.075
Adult Head
236.3
Adult Eye
168.3
Adult Brain
120.5
Adult Thoracic-Abdominal Ganglion
76.7
Adult Crop
159.2
Adult Midgut
476.6
Adult Hindgut
296.2
Adult Malpighian Tubules
(1126.8)
Adult Fat Body
487.6
Adult Salivary Gland
195
Adult Heart
435.7
Adult VirginFemale Spermatheca
404.6
Adult InseminatedFemale Spermatheca
426.7
Adult Ovary
185.5
Adult Testis
22.3
Adult Male Accessory Gland
196.3
Adult Carcass
325.6
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
157.075
Larval Midgut
170
Larval Hindgut
179.8
Larval Malpighian Tubules
369.6
Larval Fat Body
432.6
Larval Salivary Gland
160.4
Larval Trachea
210.55
Larval Carcass
131.075
Adult Head
236.3
Adult Eye
168.3
Adult Brain
120.5
Adult Thoracic-Abdominal Ganglion
76.7
Adult Crop
159.2
Adult Midgut
476.6
Adult Hindgut
296.2
Adult Malpighian Tubules
1126.8
Adult Fat Body
487.6
Adult Salivary Gland
195
Adult Heart
435.7
Adult VirginFemale Spermatheca
404.6
Adult InseminatedFemale Spermatheca
426.7
Adult Ovary
185.5
Adult Testis
22.3
Adult Male Accessory Gland
196.3
Adult Carcass
325.6
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
157.075
Larval Midgut
170
Larval Hindgut
179.8
Larval Malpighian Tubules
369.6
Larval Fat Body
432.6
Larval Salivary Gland
160.4
Larval Trachea
210.55
Larval Carcass
131.075
Adult Head
236.3
Adult Eye
168.3
Adult Brain
120.5
Adult Thoracic-Abdominal Ganglion
76.7
Adult Crop
159.2
Adult Midgut
476.6
Adult Hindgut
296.2
Adult Malpighian Tubules
1126.8
Adult Fat Body
487.6
Adult Salivary Gland
195
Adult Heart
435.7
Adult VirginFemale Spermatheca
404.6
Adult InseminatedFemale Spermatheca
426.7
Adult Ovary
185.5
Adult Testis
22.3
Adult Male Accessory Gland
196.3
Adult Carcass
325.6
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
157.075
Larval Midgut
170
Larval Hindgut
179.8
Larval Malpighian Tubules
369.6
Larval Fat Body
432.6
Larval Salivary Gland
160.4
Larval Trachea
210.55
Larval Carcass
131.075
Adult Head
236.3
Adult Eye
168.3
Adult Brain
120.5
Adult Thoracic-Abdominal Ganglion
76.7
Adult Crop
159.2
Adult Midgut
476.6
Adult Hindgut
296.2
Adult Malpighian Tubules
(1126.8)
Adult Fat Body
487.6
Adult Salivary Gland
195
Adult Heart
435.7
Adult VirginFemale Spermatheca
404.6
Adult InseminatedFemale Spermatheca
426.7
Adult Ovary
185.5
Adult Testis
22.3
Adult Male Accessory Gland
196.3
Adult Carcass
325.6
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
157.075
Larval Midgut
170
Larval Hindgut
179.8
Larval Malpighian Tubules
369.6
Larval Fat Body
432.6
Larval Salivary Gland
160.4
Larval Trachea
210.55
Larval Carcass
131.075
Adult Head
236.3
Adult Eye
168.3
Adult Brain
120.5
Adult Thoracic-Abdominal Ganglion
76.7
Adult Crop
159.2
Adult Midgut
476.6
Adult Hindgut
296.2
Adult Malpighian Tubules
1126.8
Adult Fat Body
487.6
Adult Salivary Gland
195
Adult Heart
435.7
Adult VirginFemale Spermatheca
404.6
Adult InseminatedFemale Spermatheca
426.7
Adult Ovary
185.5
Adult Testis
22.3
Adult Male Accessory Gland
196.3
Adult Carcass
325.6
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
157.075
Larval Midgut
170
Larval Hindgut
179.8
Larval Malpighian Tubules
369.6
Larval Fat Body
432.6
Larval Salivary Gland
160.4
Larval Trachea
210.55
Larval Carcass
131.075
Adult Head
236.3
Adult Eye
168.3
Adult Brain
120.5
Adult Thoracic-Abdominal Ganglion
76.7
Adult Crop
159.2
Adult Midgut
476.6
Adult Hindgut
296.2
Adult Malpighian Tubules
1126.8
Adult Fat Body
487.6
Adult Salivary Gland
195
Adult Heart
435.7
Adult VirginFemale Spermatheca
404.6
Adult InseminatedFemale Spermatheca
426.7
Adult Ovary
185.5
Adult Testis
22.3
Adult Male Accessory Gland
196.3
Adult Carcass
325.6
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
236.3
NA
Eye
168.3
NA
Brain
120.5
157.075
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
76.7
NA
Crop
159.2
170
Midgut
476.6
179.8
Hindgut
296.2
369.6
Malpighian Tubules
1126.8
432.6
Fat Body
487.6
160.4
Salivary Gland
195
NA
Heart
435.7
210.55
Trachea
NA
NA
VirginFemale Spermatheca
404.6
NA
InseminatedFemale Spermatheca
426.7
NA
Ovary
185.5
NA
Testis
22.3
NA
Male Accessory Gland
196.3
131.075
Carcass
325.6
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
5
central nervous system, larvae L3
2
central nervous system, pupae P8
2
head, virgin 1-day female
5
head, virgin 4-day female
3
head, virgin 20-day female
5
head, mated 1-day female
3
head, mated 4-day female
4
head, mated 20-day female
4
head, mated 1-day male
4
head, mated 4-day male
4
head, mated 20-day male
7
salivary gland, larvae L3 wandering
2
salivary gland, white prepupae
1
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
14
digestive system, 4-day adult
9
digestive system, 20-day adult
11
fat body, larvae L3 wandering
5
fat body, white prepupae
9
fat body, pupae P8
8
carcass, larvae L3 wandering
3
carcass, 1-day adult
5
carcass, 4-day adult
5
carcass, 20-day adult
4
ovary, virgin 4-day female
9
ovary, mated 4-day female
8
testis, mated 4-day male
2
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
5
central nervous system, larvae L3
2
central nervous system, pupae P8
2
head, virgin 1-day female
5
head, virgin 4-day female
3
head, virgin 20-day female
5
head, mated 1-day female
3
head, mated 4-day female
4
head, mated 20-day female
4
head, mated 1-day male
4
head, mated 4-day male
4
head, mated 20-day male
7
salivary gland, larvae L3 wandering
2
salivary gland, white prepupae
1
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
14
digestive system, 4-day adult
9
digestive system, 20-day adult
11
fat body, larvae L3 wandering
5
fat body, white prepupae
9
fat body, pupae P8
8
carcass, larvae L3 wandering
3
carcass, 1-day adult
5
carcass, 4-day adult
5
carcass, 20-day adult
4
ovary, virgin 4-day female
9
ovary, mated 4-day female
8
testis, mated 4-day male
2
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
5
central nervous system, larvae L3
2
central nervous system, pupae P8
2
head, virgin 1-day female
5
head, virgin 4-day female
3
head, virgin 20-day female
5
head, mated 1-day female
3
head, mated 4-day female
4
head, mated 20-day female
4
head, mated 1-day male
4
head, mated 4-day male
4
head, mated 20-day male
7
salivary gland, larvae L3 wandering
2
salivary gland, white prepupae
1
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
14
digestive system, 4-day adult
9
digestive system, 20-day adult
11
fat body, larvae L3 wandering
5
fat body, white prepupae
9
fat body, pupae P8
8
carcass, larvae L3 wandering
3
carcass, 1-day adult
5
carcass, 4-day adult
5
carcass, 20-day adult
4
ovary, virgin 4-day female
9
ovary, mated 4-day female
8
testis, mated 4-day male
2
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
5
central nervous system, larvae L3
2
central nervous system, pupae P8
2
head, virgin 1-day female
5
head, virgin 4-day female
3
head, virgin 20-day female
5
head, mated 1-day female
3
head, mated 4-day female
4
head, mated 20-day female
4
head, mated 1-day male
4
head, mated 4-day male
4
head, mated 20-day male
7
salivary gland, larvae L3 wandering
2
salivary gland, white prepupae
1
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
14
digestive system, 4-day adult
9
digestive system, 20-day adult
11
fat body, larvae L3 wandering
5
fat body, white prepupae
9
fat body, pupae P8
8
carcass, larvae L3 wandering
3
carcass, 1-day adult
5
carcass, 4-day adult
5
carcass, 20-day adult
4
ovary, virgin 4-day female
9
ovary, mated 4-day female
8
testis, mated 4-day male
2
accessory gland, mated 4-day male
2
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
5
central nervous system, larvae L3
2
central nervous system, pupae P8
2
head, virgin 1-day female
5
head, virgin 4-day female
3
head, virgin 20-day female
5
head, mated 1-day female
3
head, mated 4-day female
4
head, mated 20-day female
4
head, mated 1-day male
4
head, mated 4-day male
4
head, mated 20-day male
7
salivary gland, larvae L3 wandering
2
salivary gland, white prepupae
1
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
14
digestive system, 4-day adult
9
digestive system, 20-day adult
11
fat body, larvae L3 wandering
5
fat body, white prepupae
9
fat body, pupae P8
8
carcass, larvae L3 wandering
3
carcass, 1-day adult
5
carcass, 4-day adult
5
carcass, 20-day adult
4
ovary, virgin 4-day female
9
ovary, mated 4-day female
8
testis, mated 4-day male
2
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
5
central nervous system, larvae L3
2
central nervous system, pupae P8
2
head, virgin 1-day female
5
head, virgin 4-day female
3
head, virgin 20-day female
5
head, mated 1-day female
3
head, mated 4-day female
4
head, mated 20-day female
4
head, mated 1-day male
4
head, mated 4-day male
4
head, mated 20-day male
7
salivary gland, larvae L3 wandering
2
salivary gland, white prepupae
1
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
14
digestive system, 4-day adult
9
digestive system, 20-day adult
11
fat body, larvae L3 wandering
5
fat body, white prepupae
9
fat body, pupae P8
8
carcass, larvae L3 wandering
3
carcass, 1-day adult
5
carcass, 4-day adult
5
carcass, 20-day adult
4
ovary, virgin 4-day female
9
ovary, mated 4-day female
8
testis, mated 4-day male
2
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
5
central nervous system, larvae L3
2
central nervous system, pupae P8
2
head, virgin 1-day female
5
head, virgin 4-day female
3
head, virgin 20-day female
5
head, mated 1-day female
3
head, mated 4-day female
4
head, mated 20-day female
4
head, mated 1-day male
4
head, mated 4-day male
4
head, mated 20-day male
7
salivary gland, larvae L3 wandering
2
salivary gland, white prepupae
1
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
14
digestive system, 4-day adult
9
digestive system, 20-day adult
11
fat body, larvae L3 wandering
5
fat body, white prepupae
9
fat body, pupae P8
8
carcass, larvae L3 wandering
3
carcass, 1-day adult
5
carcass, 4-day adult
5
carcass, 20-day adult
4
ovary, virgin 4-day female
9
ovary, mated 4-day female
8
testis, mated 4-day male
2
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
5
central nervous system, larvae L3
2
central nervous system, pupae P8
2
head, virgin 1-day female
5
head, virgin 4-day female
3
head, virgin 20-day female
5
head, mated 1-day female
3
head, mated 4-day female
4
head, mated 20-day female
4
head, mated 1-day male
4
head, mated 4-day male
4
head, mated 20-day male
7
salivary gland, larvae L3 wandering
2
salivary gland, white prepupae
1
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
14
digestive system, 4-day adult
9
digestive system, 20-day adult
11
fat body, larvae L3 wandering
5
fat body, white prepupae
9
fat body, pupae P8
8
carcass, larvae L3 wandering
3
carcass, 1-day adult
5
carcass, 4-day adult
5
carcass, 20-day adult
4
ovary, virgin 4-day female
9
ovary, mated 4-day female
8
testis, mated 4-day male
2
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
21
embryo 02-04hr
18
embryo 04-06hr
14
embryo 06-08hr
13
embryo 08-10hr
12
embryo 10-12hr
14
embryo 12-14hr
9
embryo 14-16hr
12
embryo 16-18hr
11
embryo 18-20hr
10
embryo 20-22hr
11
embryo 22-24hr
13
larva L1
23
larva L2
23
larva L3 12hr old
29
larva L3 puffstage 1-2
18
larva L3 puffstage 3-6
14
larva L3 puffstage 7-9
14
white prepupae new
16
white prepupae 12hr
13
white prepupae 24hr
14
pupae 2d postWPP
13
pupae 3d postWPP
10
pupae 4d postWPP
14
adult male 01day
19
adult male 05day
19
adult male 30day
23
adult female 01day
26
adult female 05day
22
adult female 30day
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
21
embryo 02-04hr
18
embryo 04-06hr
14
embryo 06-08hr
13
embryo 08-10hr
12
embryo 10-12hr
14
embryo 12-14hr
9
embryo 14-16hr
12
embryo 16-18hr
11
embryo 18-20hr
10
embryo 20-22hr
11
embryo 22-24hr
13
larva L1
23
larva L2
23
larva L3 12hr old
(29)
larva L3 puffstage 1-2
18
larva L3 puffstage 3-6
14
larva L3 puffstage 7-9
14
white prepupae new
16
white prepupae 12hr
13
white prepupae 24hr
14
pupae 2d postWPP
13
pupae 3d postWPP
10
pupae 4d postWPP
14
adult male 01day
19
adult male 05day
19
adult male 30day
23
adult female 01day
26
adult female 05day
22
adult female 30day
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
21
embryo 02-04hr
18
embryo 04-06hr
14
embryo 06-08hr
13
embryo 08-10hr
12
embryo 10-12hr
14
embryo 12-14hr
9
embryo 14-16hr
12
embryo 16-18hr
11
embryo 18-20hr
10
embryo 20-22hr
11
embryo 22-24hr
13
larva L1
23
larva L2
23
larva L3 12hr old
29
larva L3 puffstage 1-2
18
larva L3 puffstage 3-6
14
larva L3 puffstage 7-9
14
white prepupae new
16
white prepupae 12hr
13
white prepupae 24hr
14
pupae 2d postWPP
13
pupae 3d postWPP
10
pupae 4d postWPP
14
adult male 01day
19
adult male 05day
19
adult male 30day
23
adult female 01day
26
adult female 05day
22
adult female 30day
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
21
embryo 02-04hr
18
embryo 04-06hr
14
embryo 06-08hr
13
embryo 08-10hr
12
embryo 10-12hr
14
embryo 12-14hr
9
embryo 14-16hr
12
embryo 16-18hr
11
embryo 18-20hr
10
embryo 20-22hr
11
embryo 22-24hr
13
larva L1
23
larva L2
23
larva L3 12hr old
29
larva L3 puffstage 1-2
18
larva L3 puffstage 3-6
14
larva L3 puffstage 7-9
14
white prepupae new
16
white prepupae 12hr
13
white prepupae 24hr
14
pupae 2d postWPP
13
pupae 3d postWPP
10
pupae 4d postWPP
14
adult male 01day
19
adult male 05day
19
adult male 30day
23
adult female 01day
26
adult female 05day
22
adult female 30day
22
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
21
embryo 02-04hr
18
embryo 04-06hr
14
embryo 06-08hr
13
embryo 08-10hr
12
embryo 10-12hr
14
embryo 12-14hr
9
embryo 14-16hr
12
embryo 16-18hr
11
embryo 18-20hr
10
embryo 20-22hr
11
embryo 22-24hr
13
larva L1
23
larva L2
23
larva L3 12hr old
29
larva L3 puffstage 1-2
18
larva L3 puffstage 3-6
14
larva L3 puffstage 7-9
14
white prepupae new
16
white prepupae 12hr
13
white prepupae 24hr
14
pupae 2d postWPP
13
pupae 3d postWPP
10
pupae 4d postWPP
14
adult male 01day
19
adult male 05day
19
adult male 30day
23
adult female 01day
26
adult female 05day
22
adult female 30day
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
21
embryo 02-04hr
18
embryo 04-06hr
14
embryo 06-08hr
13
embryo 08-10hr
12
embryo 10-12hr
14
embryo 12-14hr
9
embryo 14-16hr
12
embryo 16-18hr
11
embryo 18-20hr
10
embryo 20-22hr
11
embryo 22-24hr
13
larva L1
23
larva L2
23
larva L3 12hr old
29
larva L3 puffstage 1-2
18
larva L3 puffstage 3-6
14
larva L3 puffstage 7-9
14
white prepupae new
16
white prepupae 12hr
13
white prepupae 24hr
14
pupae 2d postWPP
13
pupae 3d postWPP
10
pupae 4d postWPP
14
adult male 01day
19
adult male 05day
19
adult male 30day
23
adult female 01day
26
adult female 05day
22
adult female 30day
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
21
embryo 02-04hr
18
embryo 04-06hr
14
embryo 06-08hr
13
embryo 08-10hr
12
embryo 10-12hr
14
embryo 12-14hr
9
embryo 14-16hr
12
embryo 16-18hr
11
embryo 18-20hr
10
embryo 20-22hr
11
embryo 22-24hr
13
larva L1
23
larva L2
23
larva L3 12hr old
29
larva L3 puffstage 1-2
18
larva L3 puffstage 3-6
14
larva L3 puffstage 7-9
14
white prepupae new
16
white prepupae 12hr
13
white prepupae 24hr
14
pupae 2d postWPP
13
pupae 3d postWPP
10
pupae 4d postWPP
14
adult male 01day
19
adult male 05day
19
adult male 30day
23
adult female 01day
26
adult female 05day
22
adult female 30day
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
21
embryo 02-04hr
18
embryo 04-06hr
14
embryo 06-08hr
13
embryo 08-10hr
12
embryo 10-12hr
14
embryo 12-14hr
9
embryo 14-16hr
12
embryo 16-18hr
11
embryo 18-20hr
10
embryo 20-22hr
11
embryo 22-24hr
13
larva L1
23
larva L2
23
larva L3 12hr old
29
larva L3 puffstage 1-2
18
larva L3 puffstage 3-6
14
larva L3 puffstage 7-9
14
white prepupae new
16
white prepupae 12hr
13
white prepupae 24hr
14
pupae 2d postWPP
13
pupae 3d postWPP
10
pupae 4d postWPP
14
adult male 01day
19
adult male 05day
19
adult male 30day
23
adult female 01day
26
adult female 05day
22
adult female 30day
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
12
Schneider line 2 Sg4
7
embryonic 1182-4H
6
embryonic GM2
11
embryonic Kc167
8
embryonic S1
7
embryonic S3
20
leg disc CME L1
5
wing disc CME-W2
8
wing disc ML-DmD8
10
wing disc ML-DmD9
9
wing disc ML-DmD16-c3
5
wing disc ML-DmD21
14
wing disc ML-DmD32
8
haltere disc ML-DmD17-c3
8
eye-antennal disc ML-DmD11
7
antennal disc ML-DmD20-c5
8
mixed discs ML-DmD4-c1
12
CNS ML-DmBG1-c1
7
CNS ML-DmBG2-c2
4
tumorous blood cells mbn2
5
ovary fGS/OSS
4
ovary OSC
3
ovary OSS
1
Expression Level Scale
Very low
Low
Moderate
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
12
Schneider line 2 Sg4
7
embryonic 1182-4H
6
embryonic GM2
11
embryonic Kc167
8
embryonic S1
7
embryonic S3
20
leg disc CME L1
5
wing disc CME-W2
8
wing disc ML-DmD8
10
wing disc ML-DmD9
9
wing disc ML-DmD16-c3
5
wing disc ML-DmD21
14
wing disc ML-DmD32
8
haltere disc ML-DmD17-c3
8
eye-antennal disc ML-DmD11
7
antennal disc ML-DmD20-c5
8
mixed discs ML-DmD4-c1
12
CNS ML-DmBG1-c1
7
CNS ML-DmBG2-c2
4
tumorous blood cells mbn2
5
ovary fGS/OSS
4
ovary OSC
3
ovary OSS
1
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
12
Schneider line 2 Sg4
7
embryonic 1182-4H
6
embryonic GM2
11
embryonic Kc167
8
embryonic S1
7
embryonic S3
20
leg disc CME L1
5
wing disc CME-W2
8
wing disc ML-DmD8
10
wing disc ML-DmD9
9
wing disc ML-DmD16-c3
5
wing disc ML-DmD21
14
wing disc ML-DmD32
8
haltere disc ML-DmD17-c3
8
eye-antennal disc ML-DmD11
7
antennal disc ML-DmD20-c5
8
mixed discs ML-DmD4-c1
12
CNS ML-DmBG1-c1
7
CNS ML-DmBG2-c2
4
tumorous blood cells mbn2
5
ovary fGS/OSS
4
ovary OSC
3
ovary OSS
1
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
12
Schneider line 2 Sg4
7
embryonic 1182-4H
6
embryonic GM2
11
embryonic Kc167
8
embryonic S1
7
embryonic S3
20
leg disc CME L1
5
wing disc CME-W2
8
wing disc ML-DmD8
10
wing disc ML-DmD9
9
wing disc ML-DmD16-c3
5
wing disc ML-DmD21
14
wing disc ML-DmD32
8
haltere disc ML-DmD17-c3
8
eye-antennal disc ML-DmD11
7
antennal disc ML-DmD20-c5
8
mixed discs ML-DmD4-c1
12
CNS ML-DmBG1-c1
7
CNS ML-DmBG2-c2
4
tumorous blood cells mbn2
5
ovary fGS/OSS
4
ovary OSC
3
ovary OSS
1
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
12
Schneider line 2 Sg4
7
embryonic 1182-4H
6
embryonic GM2
11
embryonic Kc167
8
embryonic S1
7
embryonic S3
20
leg disc CME L1
5
wing disc CME-W2
8
wing disc ML-DmD8
10
wing disc ML-DmD9
9
wing disc ML-DmD16-c3
5
wing disc ML-DmD21
14
wing disc ML-DmD32
8
haltere disc ML-DmD17-c3
8
eye-antennal disc ML-DmD11
7
antennal disc ML-DmD20-c5
8
mixed discs ML-DmD4-c1
12
CNS ML-DmBG1-c1
7
CNS ML-DmBG2-c2
4
tumorous blood cells mbn2
5
ovary fGS/OSS
4
ovary OSC
3
ovary OSS
1
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
12
Schneider line 2 Sg4
7
embryonic 1182-4H
6
embryonic GM2
11
embryonic Kc167
8
embryonic S1
7
embryonic S3
20
leg disc CME L1
5
wing disc CME-W2
8
wing disc ML-DmD8
10
wing disc ML-DmD9
9
wing disc ML-DmD16-c3
5
wing disc ML-DmD21
14
wing disc ML-DmD32
8
haltere disc ML-DmD17-c3
8
eye-antennal disc ML-DmD11
7
antennal disc ML-DmD20-c5
8
mixed discs ML-DmD4-c1
12
CNS ML-DmBG1-c1
7
CNS ML-DmBG2-c2
4
tumorous blood cells mbn2
5
ovary fGS/OSS
4
ovary OSC
3
ovary OSS
1
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
12
Schneider line 2 Sg4
7
embryonic 1182-4H
6
embryonic GM2
11
embryonic Kc167
8
embryonic S1
7
embryonic S3
20
leg disc CME L1
5
wing disc CME-W2
8
wing disc ML-DmD8
10
wing disc ML-DmD9
9
wing disc ML-DmD16-c3
5
wing disc ML-DmD21
14
wing disc ML-DmD32
8
haltere disc ML-DmD17-c3
8
eye-antennal disc ML-DmD11
7
antennal disc ML-DmD20-c5
8
mixed discs ML-DmD4-c1
12
CNS ML-DmBG1-c1
7
CNS ML-DmBG2-c2
4
tumorous blood cells mbn2
5
ovary fGS/OSS
4
ovary OSC
3
ovary OSS
1
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
12
Schneider line 2 Sg4
7
embryonic 1182-4H
6
embryonic GM2
11
embryonic Kc167
8
embryonic S1
7
embryonic S3
20
leg disc CME L1
5
wing disc CME-W2
8
wing disc ML-DmD8
10
wing disc ML-DmD9
9
wing disc ML-DmD16-c3
5
wing disc ML-DmD21
14
wing disc ML-DmD32
8
haltere disc ML-DmD17-c3
8
eye-antennal disc ML-DmD11
7
antennal disc ML-DmD20-c5
8
mixed discs ML-DmD4-c1
12
CNS ML-DmBG1-c1
7
CNS ML-DmBG2-c2
4
tumorous blood cells mbn2
5
ovary fGS/OSS
4
ovary OSC
3
ovary OSS
1
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
3
cold shock, 4-day adult
1
heat shock, 4-day adult
9
Cadmium 50 mM 6 hrs, larvae L3
11
Cadmium 50 mM 12 hrs, larvae L3
6
Cadmium 50 mM 48 hrs, 4-day adult
10
Cadmium 100 mM 48 hrs, 4-day adult
5
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
5
Zinc 5 mM 12 hrs, larvae L3
5
Zinc 4.5 mM 48 hrs, 4-day adult
4
Ethanol 2.5% 3 hrs, larvae L3
8
Ethanol 5% 3 hrs, larvae L3
8
Ethanol 10% 3 hrs, larvae L3
8
Caffeine 1.5 mg/ml 4 hrs, larvae L3
12
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
10
Caffeine 25 mg/ml 48 hrs, 4-day adult
3
Paraquat 5 mM 48 hrs, 4-day adult
7
Paraquat 10 mM 48 hrs, 4-day adult
11
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
10
Expression Level Scale
Very low
Low
Moderate
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
3
cold shock, 4-day adult
1
heat shock, 4-day adult
9
Cadmium 50 mM 6 hrs, larvae L3
11
Cadmium 50 mM 12 hrs, larvae L3
6
Cadmium 50 mM 48 hrs, 4-day adult
10
Cadmium 100 mM 48 hrs, 4-day adult
5
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
5
Zinc 5 mM 12 hrs, larvae L3
5
Zinc 4.5 mM 48 hrs, 4-day adult
4
Ethanol 2.5% 3 hrs, larvae L3
8
Ethanol 5% 3 hrs, larvae L3
8
Ethanol 10% 3 hrs, larvae L3
8
Caffeine 1.5 mg/ml 4 hrs, larvae L3
12
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
10
Caffeine 25 mg/ml 48 hrs, 4-day adult
3
Paraquat 5 mM 48 hrs, 4-day adult
7
Paraquat 10 mM 48 hrs, 4-day adult
11
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
3
cold shock, 4-day adult
1
heat shock, 4-day adult
9
Cadmium 50 mM 6 hrs, larvae L3
11
Cadmium 50 mM 12 hrs, larvae L3
6
Cadmium 50 mM 48 hrs, 4-day adult
10
Cadmium 100 mM 48 hrs, 4-day adult
5
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
5
Zinc 5 mM 12 hrs, larvae L3
5
Zinc 4.5 mM 48 hrs, 4-day adult
4
Ethanol 2.5% 3 hrs, larvae L3
8
Ethanol 5% 3 hrs, larvae L3
8
Ethanol 10% 3 hrs, larvae L3
8
Caffeine 1.5 mg/ml 4 hrs, larvae L3
12
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
10
Caffeine 25 mg/ml 48 hrs, 4-day adult
3
Paraquat 5 mM 48 hrs, 4-day adult
7
Paraquat 10 mM 48 hrs, 4-day adult
11
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
3
cold shock, 4-day adult
1
heat shock, 4-day adult
9
Cadmium 50 mM 6 hrs, larvae L3
11
Cadmium 50 mM 12 hrs, larvae L3
6
Cadmium 50 mM 48 hrs, 4-day adult
10
Cadmium 100 mM 48 hrs, 4-day adult
5
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
5
Zinc 5 mM 12 hrs, larvae L3
5
Zinc 4.5 mM 48 hrs, 4-day adult
4
Ethanol 2.5% 3 hrs, larvae L3
8
Ethanol 5% 3 hrs, larvae L3
8
Ethanol 10% 3 hrs, larvae L3
8
Caffeine 1.5 mg/ml 4 hrs, larvae L3
12
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
10
Caffeine 25 mg/ml 48 hrs, 4-day adult
3
Paraquat 5 mM 48 hrs, 4-day adult
7
Paraquat 10 mM 48 hrs, 4-day adult
11
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
10
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
3
cold shock, 4-day adult
1
heat shock, 4-day adult
9
Cadmium 50 mM 6 hrs, larvae L3
11
Cadmium 50 mM 12 hrs, larvae L3
6
Cadmium 50 mM 48 hrs, 4-day adult
10
Cadmium 100 mM 48 hrs, 4-day adult
5
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
5
Zinc 5 mM 12 hrs, larvae L3
5
Zinc 4.5 mM 48 hrs, 4-day adult
4
Ethanol 2.5% 3 hrs, larvae L3
8
Ethanol 5% 3 hrs, larvae L3
8
Ethanol 10% 3 hrs, larvae L3
8
Caffeine 1.5 mg/ml 4 hrs, larvae L3
12
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
10
Caffeine 25 mg/ml 48 hrs, 4-day adult
3
Paraquat 5 mM 48 hrs, 4-day adult
7
Paraquat 10 mM 48 hrs, 4-day adult
11
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
10
Expression Level Scale
Very low
Low
Moderate
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
3
cold shock, 4-day adult
1
heat shock, 4-day adult
9
Cadmium 50 mM 6 hrs, larvae L3
11
Cadmium 50 mM 12 hrs, larvae L3
6
Cadmium 50 mM 48 hrs, 4-day adult
10
Cadmium 100 mM 48 hrs, 4-day adult
5
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
5
Zinc 5 mM 12 hrs, larvae L3
5
Zinc 4.5 mM 48 hrs, 4-day adult
4
Ethanol 2.5% 3 hrs, larvae L3
8
Ethanol 5% 3 hrs, larvae L3
8
Ethanol 10% 3 hrs, larvae L3
8
Caffeine 1.5 mg/ml 4 hrs, larvae L3
12
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
10
Caffeine 25 mg/ml 48 hrs, 4-day adult
3
Paraquat 5 mM 48 hrs, 4-day adult
7
Paraquat 10 mM 48 hrs, 4-day adult
11
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
3
cold shock, 4-day adult
1
heat shock, 4-day adult
9
Cadmium 50 mM 6 hrs, larvae L3
11
Cadmium 50 mM 12 hrs, larvae L3
6
Cadmium 50 mM 48 hrs, 4-day adult
10
Cadmium 100 mM 48 hrs, 4-day adult
5
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
5
Zinc 5 mM 12 hrs, larvae L3
5
Zinc 4.5 mM 48 hrs, 4-day adult
4
Ethanol 2.5% 3 hrs, larvae L3
8
Ethanol 5% 3 hrs, larvae L3
8
Ethanol 10% 3 hrs, larvae L3
8
Caffeine 1.5 mg/ml 4 hrs, larvae L3
12
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
10
Caffeine 25 mg/ml 48 hrs, 4-day adult
3
Paraquat 5 mM 48 hrs, 4-day adult
7
Paraquat 10 mM 48 hrs, 4-day adult
11
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
3
cold shock, 4-day adult
1
heat shock, 4-day adult
9
Cadmium 50 mM 6 hrs, larvae L3
11
Cadmium 50 mM 12 hrs, larvae L3
6
Cadmium 50 mM 48 hrs, 4-day adult
10
Cadmium 100 mM 48 hrs, 4-day adult
5
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
5
Zinc 5 mM 12 hrs, larvae L3
5
Zinc 4.5 mM 48 hrs, 4-day adult
4
Ethanol 2.5% 3 hrs, larvae L3
8
Ethanol 5% 3 hrs, larvae L3
8
Ethanol 10% 3 hrs, larvae L3
8
Caffeine 1.5 mg/ml 4 hrs, larvae L3
12
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
10
Caffeine 25 mg/ml 48 hrs, 4-day adult
3
Paraquat 5 mM 48 hrs, 4-day adult
7
Paraquat 10 mM 48 hrs, 4-day adult
11
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 3 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 3 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Transgenic Constructs & Insertions
Transgenic Constructs Insertions insertion of enhancer trap binary system
Gene Ontology: Function, Process
& Cellular Component ( 2 unique terms ) Terms Based on
Experimental Evidence ( 0 terms ) Terms Based on Predictions or
Assertions ( 2 terms ) Molecular Function inferred from sequence or structural similarity with
EMBL:AF069985 Biological Process Cellular Component ( 0 terms) Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (75)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG6J6SB2 )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG67WNXM )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Anopheles gambiae
Malaria mosquito
Anopheles gambiae
Malaria mosquito
Orthologs in non-Dipteran Insects
(EOG6547VW )
Apis mellifera
Western honey bee
Amel\GB46006
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG013194
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG013193
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH20617
Atta cephalotes
Leafcutter ant
Acep\ACEP12862
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO23200
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL22874
Linepithema humile
Argentine ant
Lhum\LH18923
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB25621
Solenopsis invicta
Red fire ant
Sinv\SINV17500
Acyrthosiphon pisum
Pea aphid
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG6280HV )
Ixodes scapularis
Deer tick
Ixodes scapularis
Deer tick
Ixodes scapularis
Deer tick
Ixodes scapularis
Deer tick
Ixodes scapularis
Deer tick
Ixodes scapularis
Deer tick
Ixodes scapularis
Deer tick
Ixodes scapularis
Deer tick
Ixodes scapularis
Deer tick
Ixodes scapularis
Deer tick
Ixodes scapularis
Deer tick
Ixodes scapularis
Deer tick
Ixodes scapularis
Deer tick
Ixodes scapularis
Deer tick
Ixodes scapularis
Deer tick
Ixodes scapularis
Deer tick
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa
(EOG65QW7W )
Caenorhabditis elegans
Nematode
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Gallus gallus
Domestic chicken
Y
Gallus gallus
Domestic chicken
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Human Orthologs (3)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 5 )Bloomington Harvard VDRC Genomic Clones ( 2 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 29 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for database merge of Additional comments Other Comments External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 1 )Reported As Symbol Synonym Name Synonym Secondary FlyBase
IDs References ( 17 )Supplementary material Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] Guruharsha et al., 2011, Cell 147(3): Table S3. [FBrf0218395] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Personal communication to FlyBase Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi CenterRNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping projectDPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi CenterRNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file)Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Haecker et al., 2004, Haecker insertions.Haecker insertions. [FBrf0184338] Gene Disruption Project members, 2001-, (Computer file)(Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file)Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078] FlyBase analysis FlyBase, 1992-, FlyBase curation.FlyBase curation. [FBrf0105495] Stock list Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY.RNAi stocks available from NIG-FLY. [FBrf0218457] Website Fisher et al., 2012, BDGP insitu homepageBDGP insitu homepage [FBrf0219073] Curated genome annotation Find Enzymes, 1999.11, [Automatic annotations performed at the Celera Jamboreee.][Automatic annotations performed at the Celera Jamboreee.] [FBrf0126664]