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Gene Dmel\Art1

General Information
Symbol	Dmel\Art1	Species	D. melanogaster
Name	Arginine methyltransferase 1	Annotation symbol	CG6554
Feature type	protein_coding_gene	FlyBase ID	FBgn0037834
Gene Model Status	Current	Stock availability	5 publicly available
Also Known As	DART1
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	86C6-86C6	Sequence location	3R:6,612,203..6,613,948 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Arginine methyltransferase 1 is referred to in FlyBase by the symbol Dmel\Art1 (CG6554, FBgn0037834). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein-arginine omega-N asymmetric methyltransferase activity; histone methyltransferase activity (H4-R3 specific); protein-arginine omega-N monomethyltransferase activity; histone methyltransferase activity. There is experimental evidence that it is involved in the biological process: histone methylation; histone H4-R3 methylation; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Protein arginine N-methyltransferase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, larval salivary gland, larval trachea, adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, adult salivary gland, adult spermathecae, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1632383_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Art1. Gene sequence location is 3R:6612203..6613948.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 86C6-86C6   Limits computationally determined from genome sequence between P{PZ}hth05745 and P{EP}EP3340EP3340
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Art1 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.49 Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Art1-RA FBtr0082304  NM_141760   1528   376
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Art1-PA   FBpp0081780   42.8   376   4.76     NP_650017   AAF54556
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Protein arginine N-methyltransferase (IPR025799)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA247060   AA263412   AA695845   AA696374   AA950256   AA950295   AE014297 AAF54556   AI295288   AI296677   AI518567   AI518609   AI520263   AW942908   AY095041 AAM11369   BG636200   BG640470   BG640794   BI162645   BI162646   BI162745   BI162746   BI164378   BI172117   BI173892   BI213155   BI229391   BI235995   BI237657   BI240294   BI240339   BI242076   BI242395   BI242823   BI353516   BI356735   BI358584   BI361304   BI361315   BI362623   BI364778   BI364779   BI368829   BI370872   BI373986   BI374305   BI485007   BI578398   BI578706   BI579921   BI635031   BP546076   BP553053   BP553054   BP553066   BP553067   BX016443   BX045612   BZ665699   CO155926   CO188192   CO266255   CO269095   CO288086   CO298949   CO299717   CO302890   CO305666   CO321900   CO329287   CO332163   CO332595   CO333542   EC065925   EC065987   EC067313   EC074460   EC077901   EC079643   EC090610   EC199404   EC205240   EC210279   EC216746   EC220015   EC228600   EC230573   EC234937   EC239777   EC240924   EC251016   EC257394   EC261160   EL871035   EL871036   EL871273   EL871274   EL871397   EL871398   EL877318   EL877407   EL877483   EL877566   EV580073   EV581659   EV583221   EV600755   GH748726   GH750788   GH753540   GH754026   GH754347   GH755096   GH755378   GH757387   GH757499   GH757571   GH758619   GH758879   GH759480   GH759675   GH760593   GH772499   GH772651   GH773574   GH775216   GH777162   GH777268   GH777271   GH778026   GH780406   GH783281   GH788263   GH788561   GH789364   GH792997   GH795939   GH799772   GH800352   GH800821   GH800866   GH802718   GH804333   GH806652   GH807434   GH809609   GH811768   GH812518   GH812744   GH813829   GH814795   GH815020   GH815141   GH815574   GH816337   GH816391   GH816704   GH816891   GH817331   GH822508   GH823322   GH824195   GH825453   GH825478   GH825567   GH826148   GH827757   GH828414   GH829023   GH829188   GH831475   GH832758   GH834053   GH834562   GH836459   GH837818   GH837888   GH838044   GH840177   GH842236   GH842249   GH843056   GH843566   GH844717   GH845661   GH847093   GH847385   GH848464   GH848601   GH849046   GH849431   GH849556   GH850499   GH850874   GH856487   GH858325   GH858784   GH861754   GH862018   GH864152   GH866034   GH866488   GH867252   GH868182   GH868380   GH870066   GH871314   GH877711   GH883638   GH883667   GH885872   GH886568   GH886843   GH887021   GH887490   GH891376   GH895784   GH896118   GH897791   GH900650   GH901631   GH905970   GH907659   GH907975   GH908549   GH909754   GH910056   GH910173   GH910246   GH910881   GH911050   GH911071   GH912969   GH915073   GH915149   GH915380   GH916062   GH916111   GH917107   GH920578   GH922149   GH923278   GH928597   GH930047   GH934509   GH937090
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VGW7
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) northern blot Stage Tissue/Position (including subcellular localization) Reference embryonic stage | late   organism   (Boulanger et al., 2004) larval stage   organism   (Boulanger et al., 2004) adult stage | male   organism   (Boulanger et al., 2004) adult stage | female   organism   (Boulanger et al., 2004) oogenesis & adult stage | female   ovary   (Boulanger et al., 2004)
Additional Descriptive Data
	Expression of Art1 on Northern blot is highest in females and ovaries. (Boulanger et al., 2004)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011) western blot Stage Tissue/Position (including subcellular localization) Reference embryonic stage | early   organism   (Boulanger et al., 2004) embryonic stage | late   organism   (Boulanger et al., 2004) adult stage | female   organism   (Boulanger et al., 2004) ovary   (Boulanger et al., 2004)
Additional Descriptive Data
	Early and late embryos have increased expression of Art1 protein which does not correlate with the mRNA expression. (Boulanger et al., 2004)
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, larval salivary gland, larval trachea, adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, adult salivary gland, adult spermathecae, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    966.475 Larval Midgut    193.1 Larval Hindgut    333.9 Larval Malpighian Tubules    230.8 Larval Fat Body    129.5 Larval Salivary Gland    699.3 Larval Trachea    616.975 Larval Carcass    465.75 Adult Head    145.7 Adult Eye    175.025 Adult Brain    181.1 Adult Thoracic-Abdominal Ganglion    242.5 Adult Crop    166.4 Adult Midgut    180.4 Adult Hindgut    169.4 Adult Malpighian Tubules    189 Adult Fat Body    207.7 Adult Salivary Gland    192.1 Adult Heart    183.775 Adult VirginFemale Spermatheca    110.1 Adult InseminatedFemale Spermatheca    125.5 Adult Ovary    1014.5 Adult Testis    167.7 Adult Male Accessory Gland    477.4 Adult Carcass    148.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (966.475) Larval Midgut    193.1 Larval Hindgut    333.9 Larval Malpighian Tubules    230.8 Larval Fat Body    129.5 Larval Salivary Gland  (699.3) Larval Trachea  (616.975) Larval Carcass    465.75 Adult Head    145.7 Adult Eye    175.025 Adult Brain    181.1 Adult Thoracic-Abdominal Ganglion    242.5 Adult Crop    166.4 Adult Midgut    180.4 Adult Hindgut    169.4 Adult Malpighian Tubules    189 Adult Fat Body    207.7 Adult Salivary Gland    192.1 Adult Heart    183.775 Adult VirginFemale Spermatheca    110.1 Adult InseminatedFemale Spermatheca    125.5 Adult Ovary  (1014.5) Adult Testis    167.7 Adult Male Accessory Gland    477.4 Adult Carcass    148.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    966.475 Larval Midgut    193.1 Larval Hindgut    333.9 Larval Malpighian Tubules    230.8 Larval Fat Body    129.5 Larval Salivary Gland    699.3 Larval Trachea    616.975 Larval Carcass    465.75 Adult Head    145.7 Adult Eye    175.025 Adult Brain    181.1 Adult Thoracic-Abdominal Ganglion    242.5 Adult Crop    166.4 Adult Midgut    180.4 Adult Hindgut    169.4 Adult Malpighian Tubules    189 Adult Fat Body    207.7 Adult Salivary Gland    192.1 Adult Heart    183.775 Adult VirginFemale Spermatheca    110.1 Adult InseminatedFemale Spermatheca    125.5 Adult Ovary  1014.5 Adult Testis    167.7 Adult Male Accessory Gland    477.4 Adult Carcass    148.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    966.475 Larval Midgut    193.1 Larval Hindgut    333.9 Larval Malpighian Tubules    230.8 Larval Fat Body    129.5 Larval Salivary Gland    699.3 Larval Trachea    616.975 Larval Carcass    465.75 Adult Head    145.7 Adult Eye    175.025 Adult Brain    181.1 Adult Thoracic-Abdominal Ganglion    242.5 Adult Crop    166.4 Adult Midgut    180.4 Adult Hindgut    169.4 Adult Malpighian Tubules    189 Adult Fat Body    207.7 Adult Salivary Gland    192.1 Adult Heart    183.775 Adult VirginFemale Spermatheca    110.1 Adult InseminatedFemale Spermatheca    125.5 Adult Ovary    1014.5 Adult Testis    167.7 Adult Male Accessory Gland    477.4 Adult Carcass    148.9 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    966.475 Larval Midgut    193.1 Larval Hindgut    333.9 Larval Malpighian Tubules    230.8 Larval Fat Body    129.5 Larval Salivary Gland    699.3 Larval Trachea    616.975 Larval Carcass    465.75 Adult Head    145.7 Adult Eye    175.025 Adult Brain    181.1 Adult Thoracic-Abdominal Ganglion    242.5 Adult Crop    166.4 Adult Midgut    180.4 Adult Hindgut    169.4 Adult Malpighian Tubules    189 Adult Fat Body    207.7 Adult Salivary Gland    192.1 Adult Heart    183.775 Adult VirginFemale Spermatheca    110.1 Adult InseminatedFemale Spermatheca    125.5 Adult Ovary    1014.5 Adult Testis    167.7 Adult Male Accessory Gland    477.4 Adult Carcass    148.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (966.475) Larval Midgut    193.1 Larval Hindgut    333.9 Larval Malpighian Tubules    230.8 Larval Fat Body    129.5 Larval Salivary Gland  699.3 Larval Trachea  616.975 Larval Carcass    465.75 Adult Head    145.7 Adult Eye    175.025 Adult Brain    181.1 Adult Thoracic-Abdominal Ganglion    242.5 Adult Crop    166.4 Adult Midgut    180.4 Adult Hindgut    169.4 Adult Malpighian Tubules    189 Adult Fat Body    207.7 Adult Salivary Gland    192.1 Adult Heart    183.775 Adult VirginFemale Spermatheca    110.1 Adult InseminatedFemale Spermatheca    125.5 Adult Ovary  (1014.5) Adult Testis    167.7 Adult Male Accessory Gland    477.4 Adult Carcass    148.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    966.475 Larval Midgut    193.1 Larval Hindgut    333.9 Larval Malpighian Tubules    230.8 Larval Fat Body    129.5 Larval Salivary Gland    699.3 Larval Trachea    616.975 Larval Carcass    465.75 Adult Head    145.7 Adult Eye    175.025 Adult Brain    181.1 Adult Thoracic-Abdominal Ganglion    242.5 Adult Crop    166.4 Adult Midgut    180.4 Adult Hindgut    169.4 Adult Malpighian Tubules    189 Adult Fat Body    207.7 Adult Salivary Gland    192.1 Adult Heart    183.775 Adult VirginFemale Spermatheca    110.1 Adult InseminatedFemale Spermatheca    125.5 Adult Ovary  1014.5 Adult Testis    167.7 Adult Male Accessory Gland    477.4 Adult Carcass    148.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    966.475 Larval Midgut    193.1 Larval Hindgut    333.9 Larval Malpighian Tubules    230.8 Larval Fat Body    129.5 Larval Salivary Gland    699.3 Larval Trachea    616.975 Larval Carcass    465.75 Adult Head    145.7 Adult Eye    175.025 Adult Brain    181.1 Adult Thoracic-Abdominal Ganglion    242.5 Adult Crop    166.4 Adult Midgut    180.4 Adult Hindgut    169.4 Adult Malpighian Tubules    189 Adult Fat Body    207.7 Adult Salivary Gland    192.1 Adult Heart    183.775 Adult VirginFemale Spermatheca    110.1 Adult InseminatedFemale Spermatheca    125.5 Adult Ovary    1014.5 Adult Testis    167.7 Adult Male Accessory Gland    477.4 Adult Carcass    148.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    145.7   NA  Eye    175.025   NA  Brain    181.1   966.475  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    242.5   NA  Crop    166.4   193.1  Midgut    180.4   333.9  Hindgut    169.4   230.8  Malpighian Tubules    189   129.5  Fat Body    207.7   699.3  Salivary Gland    192.1   NA  Heart    183.775   616.975  Trachea    NA   NA  VirginFemale Spermatheca    110.1   NA  InseminatedFemale Spermatheca    125.5   NA  Ovary    1014.5   NA  Testis    167.7   NA  Male Accessory Gland    477.4   465.75  Carcass    148.9 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    51 central nervous system, larvae L3    62 central nervous system, pupae P8    15 head, virgin 1-day female    7 head, virgin 4-day female    7 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    11 head, mated 20-day female    6 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    15 salivary gland, larvae L3 wandering    5 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    6 digestive system, 4-day adult    14 digestive system, 20-day adult    14 fat body, larvae L3 wandering    4 fat body, white prepupae    12 fat body, pupae P8    11 carcass, larvae L3 wandering    49 carcass, 1-day adult    7 carcass, 4-day adult    15 carcass, 20-day adult    10 ovary, virgin 4-day female    115 ovary, mated 4-day female    102 testis, mated 4-day male    21 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (51) central nervous system, larvae L3  (62) central nervous system, pupae P8    15 head, virgin 1-day female    7 head, virgin 4-day female    7 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    11 head, mated 20-day female    6 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    15 salivary gland, larvae L3 wandering    5 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    6 digestive system, 4-day adult    14 digestive system, 20-day adult    14 fat body, larvae L3 wandering    4 fat body, white prepupae    12 fat body, pupae P8    11 carcass, larvae L3 wandering  (49) carcass, 1-day adult    7 carcass, 4-day adult    15 carcass, 20-day adult    10 ovary, virgin 4-day female  (115) ovary, mated 4-day female  (102) testis, mated 4-day male    21 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    51 central nervous system, larvae L3    62 central nervous system, pupae P8    15 head, virgin 1-day female    7 head, virgin 4-day female    7 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    11 head, mated 20-day female    6 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    15 salivary gland, larvae L3 wandering    5 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    6 digestive system, 4-day adult    14 digestive system, 20-day adult    14 fat body, larvae L3 wandering    4 fat body, white prepupae    12 fat body, pupae P8    11 carcass, larvae L3 wandering    49 carcass, 1-day adult    7 carcass, 4-day adult    15 carcass, 20-day adult    10 ovary, virgin 4-day female  (115) ovary, mated 4-day female  102 testis, mated 4-day male    21 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    51 central nervous system, larvae L3    62 central nervous system, pupae P8    15 head, virgin 1-day female    7 head, virgin 4-day female    7 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    11 head, mated 20-day female    6 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    15 salivary gland, larvae L3 wandering    5 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    6 digestive system, 4-day adult    14 digestive system, 20-day adult    14 fat body, larvae L3 wandering    4 fat body, white prepupae    12 fat body, pupae P8    11 carcass, larvae L3 wandering    49 carcass, 1-day adult    7 carcass, 4-day adult    15 carcass, 20-day adult    10 ovary, virgin 4-day female    115 ovary, mated 4-day female    102 testis, mated 4-day male    21 accessory gland, mated 4-day male    13 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    51 central nervous system, larvae L3    62 central nervous system, pupae P8    15 head, virgin 1-day female    7 head, virgin 4-day female    7 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    11 head, mated 20-day female    6 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    15 salivary gland, larvae L3 wandering    5 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    6 digestive system, 4-day adult    14 digestive system, 20-day adult    14 fat body, larvae L3 wandering    4 fat body, white prepupae    12 fat body, pupae P8    11 carcass, larvae L3 wandering    49 carcass, 1-day adult    7 carcass, 4-day adult    15 carcass, 20-day adult    10 ovary, virgin 4-day female    115 ovary, mated 4-day female    102 testis, mated 4-day male    21 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (51) central nervous system, larvae L3  (62) central nervous system, pupae P8    15 head, virgin 1-day female    7 head, virgin 4-day female    7 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    11 head, mated 20-day female    6 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    15 salivary gland, larvae L3 wandering    5 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    6 digestive system, 4-day adult    14 digestive system, 20-day adult    14 fat body, larvae L3 wandering    4 fat body, white prepupae    12 fat body, pupae P8    11 carcass, larvae L3 wandering  (49) carcass, 1-day adult    7 carcass, 4-day adult    15 carcass, 20-day adult    10 ovary, virgin 4-day female  (115) ovary, mated 4-day female  (102) testis, mated 4-day male    21 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    51 central nervous system, larvae L3    62 central nervous system, pupae P8    15 head, virgin 1-day female    7 head, virgin 4-day female    7 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    11 head, mated 20-day female    6 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    15 salivary gland, larvae L3 wandering    5 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    6 digestive system, 4-day adult    14 digestive system, 20-day adult    14 fat body, larvae L3 wandering    4 fat body, white prepupae    12 fat body, pupae P8    11 carcass, larvae L3 wandering    49 carcass, 1-day adult    7 carcass, 4-day adult    15 carcass, 20-day adult    10 ovary, virgin 4-day female  115 ovary, mated 4-day female  102 testis, mated 4-day male    21 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    51 central nervous system, larvae L3    62 central nervous system, pupae P8    15 head, virgin 1-day female    7 head, virgin 4-day female    7 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    11 head, mated 20-day female    6 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    15 salivary gland, larvae L3 wandering    5 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    6 digestive system, 4-day adult    14 digestive system, 20-day adult    14 fat body, larvae L3 wandering    4 fat body, white prepupae    12 fat body, pupae P8    11 carcass, larvae L3 wandering    49 carcass, 1-day adult    7 carcass, 4-day adult    15 carcass, 20-day adult    10 ovary, virgin 4-day female    115 ovary, mated 4-day female    102 testis, mated 4-day male    21 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    258 embryo 02-04hr    224 embryo 04-06hr    114 embryo 06-08hr    113 embryo 08-10hr    106 embryo 10-12hr    74 embryo 12-14hr    60 embryo 14-16hr    60 embryo 16-18hr    38 embryo 18-20hr    16 embryo 20-22hr    28 embryo 22-24hr    28 larva L1    107 larva L2    61 larva L3 12hr old    44 larva L3 puffstage 1-2    43 larva L3 puffstage 3-6    53 larva L3 puffstage 7-9    70 white prepupae new    65 white prepupae 12hr    62 white prepupae 24hr    59 pupae 2d postWPP    28 pupae 3d postWPP    14 pupae 4d postWPP    25 adult male 01day    16 adult male 05day    19 adult male 30day    24 adult female 01day    124 adult female 05day    165 adult female 30day    169 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (258) embryo 02-04hr  (224) embryo 04-06hr  (114) embryo 06-08hr  (113) embryo 08-10hr  (106) embryo 10-12hr  (74) embryo 12-14hr  (60) embryo 14-16hr  (60) embryo 16-18hr  (38) embryo 18-20hr    16 embryo 20-22hr  (28) embryo 22-24hr  (28) larva L1  (107) larva L2  (61) larva L3 12hr old  (44) larva L3 puffstage 1-2  (43) larva L3 puffstage 3-6  (53) larva L3 puffstage 7-9  (70) white prepupae new  (65) white prepupae 12hr  (62) white prepupae 24hr  (59) pupae 2d postWPP  (28) pupae 3d postWPP    14 pupae 4d postWPP    25 adult male 01day    16 adult male 05day    19 adult male 30day    24 adult female 01day  (124) adult female 05day  (165) adult female 30day  (169) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (258) embryo 02-04hr  (224) embryo 04-06hr  (114) embryo 06-08hr  (113) embryo 08-10hr  106 embryo 10-12hr    74 embryo 12-14hr    60 embryo 14-16hr    60 embryo 16-18hr    38 embryo 18-20hr    16 embryo 20-22hr    28 embryo 22-24hr    28 larva L1  107 larva L2    61 larva L3 12hr old    44 larva L3 puffstage 1-2    43 larva L3 puffstage 3-6    53 larva L3 puffstage 7-9    70 white prepupae new    65 white prepupae 12hr    62 white prepupae 24hr    59 pupae 2d postWPP    28 pupae 3d postWPP    14 pupae 4d postWPP    25 adult male 01day    16 adult male 05day    19 adult male 30day    24 adult female 01day  (124) adult female 05day  (165) adult female 30day  (169) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    258 embryo 02-04hr    224 embryo 04-06hr    114 embryo 06-08hr    113 embryo 08-10hr    106 embryo 10-12hr    74 embryo 12-14hr    60 embryo 14-16hr    60 embryo 16-18hr    38 embryo 18-20hr    16 embryo 20-22hr    28 embryo 22-24hr    28 larva L1    107 larva L2    61 larva L3 12hr old    44 larva L3 puffstage 1-2    43 larva L3 puffstage 3-6    53 larva L3 puffstage 7-9    70 white prepupae new    65 white prepupae 12hr    62 white prepupae 24hr    59 pupae 2d postWPP    28 pupae 3d postWPP    14 pupae 4d postWPP    25 adult male 01day    16 adult male 05day    19 adult male 30day    24 adult female 01day    124 adult female 05day    165 adult female 30day    169 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    258 embryo 02-04hr    224 embryo 04-06hr    114 embryo 06-08hr    113 embryo 08-10hr    106 embryo 10-12hr    74 embryo 12-14hr    60 embryo 14-16hr    60 embryo 16-18hr    38 embryo 18-20hr    16 embryo 20-22hr    28 embryo 22-24hr    28 larva L1    107 larva L2    61 larva L3 12hr old    44 larva L3 puffstage 1-2    43 larva L3 puffstage 3-6    53 larva L3 puffstage 7-9    70 white prepupae new    65 white prepupae 12hr    62 white prepupae 24hr    59 pupae 2d postWPP    28 pupae 3d postWPP    14 pupae 4d postWPP    25 adult male 01day    16 adult male 05day    19 adult male 30day    24 adult female 01day    124 adult female 05day    165 adult female 30day    169 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (258) embryo 02-04hr  (224) embryo 04-06hr  (114) embryo 06-08hr  (113) embryo 08-10hr  (106) embryo 10-12hr  (74) embryo 12-14hr  (60) embryo 14-16hr  (60) embryo 16-18hr  (38) embryo 18-20hr    16 embryo 20-22hr  28 embryo 22-24hr  28 larva L1  (107) larva L2  (61) larva L3 12hr old  (44) larva L3 puffstage 1-2  (43) larva L3 puffstage 3-6  (53) larva L3 puffstage 7-9  (70) white prepupae new  (65) white prepupae 12hr  (62) white prepupae 24hr  (59) pupae 2d postWPP  28 pupae 3d postWPP    14 pupae 4d postWPP    25 adult male 01day    16 adult male 05day    19 adult male 30day    24 adult female 01day  (124) adult female 05day  (165) adult female 30day  (169) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (258) embryo 02-04hr  (224) embryo 04-06hr  114 embryo 06-08hr  113 embryo 08-10hr  106 embryo 10-12hr    74 embryo 12-14hr    60 embryo 14-16hr    60 embryo 16-18hr    38 embryo 18-20hr    16 embryo 20-22hr    28 embryo 22-24hr    28 larva L1  107 larva L2    61 larva L3 12hr old    44 larva L3 puffstage 1-2    43 larva L3 puffstage 3-6    53 larva L3 puffstage 7-9    70 white prepupae new    65 white prepupae 12hr    62 white prepupae 24hr    59 pupae 2d postWPP    28 pupae 3d postWPP    14 pupae 4d postWPP    25 adult male 01day    16 adult male 05day    19 adult male 30day    24 adult female 01day  124 adult female 05day  (165) adult female 30day  (169) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    258 embryo 02-04hr    224 embryo 04-06hr    114 embryo 06-08hr    113 embryo 08-10hr    106 embryo 10-12hr    74 embryo 12-14hr    60 embryo 14-16hr    60 embryo 16-18hr    38 embryo 18-20hr    16 embryo 20-22hr    28 embryo 22-24hr    28 larva L1    107 larva L2    61 larva L3 12hr old    44 larva L3 puffstage 1-2    43 larva L3 puffstage 3-6    53 larva L3 puffstage 7-9    70 white prepupae new    65 white prepupae 12hr    62 white prepupae 24hr    59 pupae 2d postWPP    28 pupae 3d postWPP    14 pupae 4d postWPP    25 adult male 01day    16 adult male 05day    19 adult male 30day    24 adult female 01day    124 adult female 05day    165 adult female 30day    169 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    100 Schneider line 2 Sg4    69 embryonic 1182-4H    104 embryonic GM2    66 embryonic Kc167    48 embryonic S1    63 embryonic S3    63 leg disc CME L1    104 wing disc CME-W2    61 wing disc ML-DmD8    76 wing disc ML-DmD9    89 wing disc ML-DmD16-c3    73 wing disc ML-DmD21    97 wing disc ML-DmD32    54 haltere disc ML-DmD17-c3    114 eye-antennal disc ML-DmD11    75 antennal disc ML-DmD20-c5    85 mixed discs ML-DmD4-c1    83 CNS ML-DmBG1-c1    79 CNS ML-DmBG2-c2    59 tumorous blood cells mbn2    44 ovary fGS/OSS    110 ovary OSC    55 ovary OSS    47 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (100) Schneider line 2 Sg4  (69) embryonic 1182-4H  (104) embryonic GM2  (66) embryonic Kc167  (48) embryonic S1  (63) embryonic S3  (63) leg disc CME L1  (104) wing disc CME-W2  (61) wing disc ML-DmD8  (76) wing disc ML-DmD9  (89) wing disc ML-DmD16-c3  (73) wing disc ML-DmD21  (97) wing disc ML-DmD32  (54) haltere disc ML-DmD17-c3  (114) eye-antennal disc ML-DmD11  (75) antennal disc ML-DmD20-c5  (85) mixed discs ML-DmD4-c1  (83) CNS ML-DmBG1-c1  (79) CNS ML-DmBG2-c2  (59) tumorous blood cells mbn2  (44) ovary fGS/OSS  (110) ovary OSC  (55) ovary OSS  (47) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    100 Schneider line 2 Sg4    69 embryonic 1182-4H  104 embryonic GM2    66 embryonic Kc167    48 embryonic S1    63 embryonic S3    63 leg disc CME L1  104 wing disc CME-W2    61 wing disc ML-DmD8    76 wing disc ML-DmD9    89 wing disc ML-DmD16-c3    73 wing disc ML-DmD21    97 wing disc ML-DmD32    54 haltere disc ML-DmD17-c3  (114) eye-antennal disc ML-DmD11    75 antennal disc ML-DmD20-c5    85 mixed discs ML-DmD4-c1    83 CNS ML-DmBG1-c1    79 CNS ML-DmBG2-c2    59 tumorous blood cells mbn2    44 ovary fGS/OSS  (110) ovary OSC    55 ovary OSS    47 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    100 Schneider line 2 Sg4    69 embryonic 1182-4H    104 embryonic GM2    66 embryonic Kc167    48 embryonic S1    63 embryonic S3    63 leg disc CME L1    104 wing disc CME-W2    61 wing disc ML-DmD8    76 wing disc ML-DmD9    89 wing disc ML-DmD16-c3    73 wing disc ML-DmD21    97 wing disc ML-DmD32    54 haltere disc ML-DmD17-c3    114 eye-antennal disc ML-DmD11    75 antennal disc ML-DmD20-c5    85 mixed discs ML-DmD4-c1    83 CNS ML-DmBG1-c1    79 CNS ML-DmBG2-c2    59 tumorous blood cells mbn2    44 ovary fGS/OSS    110 ovary OSC    55 ovary OSS    47 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    100 Schneider line 2 Sg4    69 embryonic 1182-4H    104 embryonic GM2    66 embryonic Kc167    48 embryonic S1    63 embryonic S3    63 leg disc CME L1    104 wing disc CME-W2    61 wing disc ML-DmD8    76 wing disc ML-DmD9    89 wing disc ML-DmD16-c3    73 wing disc ML-DmD21    97 wing disc ML-DmD32    54 haltere disc ML-DmD17-c3    114 eye-antennal disc ML-DmD11    75 antennal disc ML-DmD20-c5    85 mixed discs ML-DmD4-c1    83 CNS ML-DmBG1-c1    79 CNS ML-DmBG2-c2    59 tumorous blood cells mbn2    44 ovary fGS/OSS    110 ovary OSC    55 ovary OSS    47 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (100) Schneider line 2 Sg4  (69) embryonic 1182-4H  (104) embryonic GM2  (66) embryonic Kc167  (48) embryonic S1  (63) embryonic S3  (63) leg disc CME L1  (104) wing disc CME-W2  (61) wing disc ML-DmD8  (76) wing disc ML-DmD9  (89) wing disc ML-DmD16-c3  (73) wing disc ML-DmD21  (97) wing disc ML-DmD32  (54) haltere disc ML-DmD17-c3  (114) eye-antennal disc ML-DmD11  (75) antennal disc ML-DmD20-c5  (85) mixed discs ML-DmD4-c1  (83) CNS ML-DmBG1-c1  (79) CNS ML-DmBG2-c2  (59) tumorous blood cells mbn2  (44) ovary fGS/OSS  (110) ovary OSC  (55) ovary OSS  (47) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    100 Schneider line 2 Sg4    69 embryonic 1182-4H  104 embryonic GM2    66 embryonic Kc167    48 embryonic S1    63 embryonic S3    63 leg disc CME L1  104 wing disc CME-W2    61 wing disc ML-DmD8    76 wing disc ML-DmD9    89 wing disc ML-DmD16-c3    73 wing disc ML-DmD21    97 wing disc ML-DmD32    54 haltere disc ML-DmD17-c3  114 eye-antennal disc ML-DmD11    75 antennal disc ML-DmD20-c5    85 mixed discs ML-DmD4-c1    83 CNS ML-DmBG1-c1    79 CNS ML-DmBG2-c2    59 tumorous blood cells mbn2    44 ovary fGS/OSS  110 ovary OSC    55 ovary OSS    47 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    100 Schneider line 2 Sg4    69 embryonic 1182-4H    104 embryonic GM2    66 embryonic Kc167    48 embryonic S1    63 embryonic S3    63 leg disc CME L1    104 wing disc CME-W2    61 wing disc ML-DmD8    76 wing disc ML-DmD9    89 wing disc ML-DmD16-c3    73 wing disc ML-DmD21    97 wing disc ML-DmD32    54 haltere disc ML-DmD17-c3    114 eye-antennal disc ML-DmD11    75 antennal disc ML-DmD20-c5    85 mixed discs ML-DmD4-c1    83 CNS ML-DmBG1-c1    79 CNS ML-DmBG2-c2    59 tumorous blood cells mbn2    44 ovary fGS/OSS    110 ovary OSC    55 ovary OSS    47 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    50 cold shock, 4-day adult    28 heat shock, 4-day adult    56 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3    32 Cadmium 50 mM 48 hrs, 4-day adult    48 Cadmium 100 mM 48 hrs, 4-day adult    68 Copper 0.5 mM 12 hrs, larvae L3    29 Copper 15 mM 48 hrs, 4-day adult    26 Zinc 5 mM 12 hrs, larvae L3    19 Zinc 4.5 mM 48 hrs, 4-day adult    20 Ethanol 2.5% 3 hrs, larvae L3    108 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    60 Caffeine 25 mg/ml 48 hrs, 4-day adult    31 Paraquat 5 mM 48 hrs, 4-day adult    66 Paraquat 10 mM 48 hrs, 4-day adult    61 Rotenone 2 μg 12 hrs, larvae L3    36 Rotenone 8 μg 12 hrs, larvae L3    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (50) cold shock, 4-day adult  (28) heat shock, 4-day adult  (56) Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3  (32) Cadmium 50 mM 48 hrs, 4-day adult  (48) Cadmium 100 mM 48 hrs, 4-day adult  (68) Copper 0.5 mM 12 hrs, larvae L3  (29) Copper 15 mM 48 hrs, 4-day adult  26 Zinc 5 mM 12 hrs, larvae L3    19 Zinc 4.5 mM 48 hrs, 4-day adult    20 Ethanol 2.5% 3 hrs, larvae L3  (108) Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3  (31) Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (60) Caffeine 25 mg/ml 48 hrs, 4-day adult  (31) Paraquat 5 mM 48 hrs, 4-day adult  (66) Paraquat 10 mM 48 hrs, 4-day adult  (61) Rotenone 2 μg 12 hrs, larvae L3  (36) Rotenone 8 μg 12 hrs, larvae L3  (31) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    50 cold shock, 4-day adult    28 heat shock, 4-day adult    56 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3    32 Cadmium 50 mM 48 hrs, 4-day adult    48 Cadmium 100 mM 48 hrs, 4-day adult    68 Copper 0.5 mM 12 hrs, larvae L3    29 Copper 15 mM 48 hrs, 4-day adult    26 Zinc 5 mM 12 hrs, larvae L3    19 Zinc 4.5 mM 48 hrs, 4-day adult    20 Ethanol 2.5% 3 hrs, larvae L3  (108) Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    60 Caffeine 25 mg/ml 48 hrs, 4-day adult    31 Paraquat 5 mM 48 hrs, 4-day adult    66 Paraquat 10 mM 48 hrs, 4-day adult    61 Rotenone 2 μg 12 hrs, larvae L3    36 Rotenone 8 μg 12 hrs, larvae L3    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    50 cold shock, 4-day adult    28 heat shock, 4-day adult    56 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3    32 Cadmium 50 mM 48 hrs, 4-day adult    48 Cadmium 100 mM 48 hrs, 4-day adult    68 Copper 0.5 mM 12 hrs, larvae L3    29 Copper 15 mM 48 hrs, 4-day adult    26 Zinc 5 mM 12 hrs, larvae L3    19 Zinc 4.5 mM 48 hrs, 4-day adult    20 Ethanol 2.5% 3 hrs, larvae L3    108 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    60 Caffeine 25 mg/ml 48 hrs, 4-day adult    31 Paraquat 5 mM 48 hrs, 4-day adult    66 Paraquat 10 mM 48 hrs, 4-day adult    61 Rotenone 2 μg 12 hrs, larvae L3    36 Rotenone 8 μg 12 hrs, larvae L3    31 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    50 cold shock, 4-day adult    28 heat shock, 4-day adult    56 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3    32 Cadmium 50 mM 48 hrs, 4-day adult    48 Cadmium 100 mM 48 hrs, 4-day adult    68 Copper 0.5 mM 12 hrs, larvae L3    29 Copper 15 mM 48 hrs, 4-day adult    26 Zinc 5 mM 12 hrs, larvae L3    19 Zinc 4.5 mM 48 hrs, 4-day adult    20 Ethanol 2.5% 3 hrs, larvae L3    108 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    60 Caffeine 25 mg/ml 48 hrs, 4-day adult    31 Paraquat 5 mM 48 hrs, 4-day adult    66 Paraquat 10 mM 48 hrs, 4-day adult    61 Rotenone 2 μg 12 hrs, larvae L3    36 Rotenone 8 μg 12 hrs, larvae L3    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (50) cold shock, 4-day adult  28 heat shock, 4-day adult  (56) Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3  32 Cadmium 50 mM 48 hrs, 4-day adult  (48) Cadmium 100 mM 48 hrs, 4-day adult  (68) Copper 0.5 mM 12 hrs, larvae L3  29 Copper 15 mM 48 hrs, 4-day adult  26 Zinc 5 mM 12 hrs, larvae L3    19 Zinc 4.5 mM 48 hrs, 4-day adult    20 Ethanol 2.5% 3 hrs, larvae L3  (108) Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3  31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (60) Caffeine 25 mg/ml 48 hrs, 4-day adult  31 Paraquat 5 mM 48 hrs, 4-day adult  (66) Paraquat 10 mM 48 hrs, 4-day adult  (61) Rotenone 2 μg 12 hrs, larvae L3  (36) Rotenone 8 μg 12 hrs, larvae L3  31 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    50 cold shock, 4-day adult    28 heat shock, 4-day adult    56 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3    32 Cadmium 50 mM 48 hrs, 4-day adult    48 Cadmium 100 mM 48 hrs, 4-day adult    68 Copper 0.5 mM 12 hrs, larvae L3    29 Copper 15 mM 48 hrs, 4-day adult    26 Zinc 5 mM 12 hrs, larvae L3    19 Zinc 4.5 mM 48 hrs, 4-day adult    20 Ethanol 2.5% 3 hrs, larvae L3  108 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    60 Caffeine 25 mg/ml 48 hrs, 4-day adult    31 Paraquat 5 mM 48 hrs, 4-day adult    66 Paraquat 10 mM 48 hrs, 4-day adult    61 Rotenone 2 μg 12 hrs, larvae L3    36 Rotenone 8 μg 12 hrs, larvae L3    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    50 cold shock, 4-day adult    28 heat shock, 4-day adult    56 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3    32 Cadmium 50 mM 48 hrs, 4-day adult    48 Cadmium 100 mM 48 hrs, 4-day adult    68 Copper 0.5 mM 12 hrs, larvae L3    29 Copper 15 mM 48 hrs, 4-day adult    26 Zinc 5 mM 12 hrs, larvae L3    19 Zinc 4.5 mM 48 hrs, 4-day adult    20 Ethanol 2.5% 3 hrs, larvae L3    108 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    60 Caffeine 25 mg/ml 48 hrs, 4-day adult    31 Paraquat 5 mM 48 hrs, 4-day adult    66 Paraquat 10 mM 48 hrs, 4-day adult    61 Rotenone 2 μg 12 hrs, larvae L3    36 Rotenone 8 μg 12 hrs, larvae L3    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_13 mE1_20_mRNA_expression_cluster_02
External Data & Images
Linkouts	BDGP expression data • LD28808 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037834 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6554-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pupal stage | recessive Art150 viable Art1KG09631 viable, with Scer\GAL4pnr-MD237 Art1GD11959 Other Phenotypes Allele developmental rate defective | pupal stage | recessive Art150 Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of Art1 Class Mutagen Stocks Known lesion Art1KG09631 P-element activity 1 Yes Art1NP2028 1 -- Art150 Delta2-3 0 Yes
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Art1 Class Mutagen Stocks Known lesion Art1GD11959 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Art1GL01072 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Art1JF01306 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Art1KK101196 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes Art1t4 in vitro construct - genomic fragment 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6159 (Ryder, 2004.4.26) Df(3R)Exel7305 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD11959} NA P{KK101196} NA P{TRiP.GL01072} NA P{TRiP.JF01306} NA characterization construct P{Mcm5+t4} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap binary system P{GawB}Art1NP2028 No miscellaneous insertions P{SUPor-P}Art1KG09631 NA P{SUPor-P}KG05409 NA P{wHy}Mcm5DG12108 NA
Gene Ontology: Function, Process & Cellular Component ( 8 unique terms )
Terms Based on Experimental Evidence ( 7 terms )
Molecular Function
CV term Evidence References
histone methyltransferase activity inferred from direct assay (Boulanger et al., 2004) histone methyltransferase activity (H4-R3 specific) inferred from direct assay (Kimura et al., 2008) protein-arginine omega-N asymmetric methyltransferase activity inferred from direct assay (Boulanger et al., 2004) protein-arginine omega-N monomethyltransferase activity inferred from direct assay (Boulanger et al., 2004)
Biological Process
CV term Evidence References
histone H4-R3 methylation inferred from direct assay (Kimura et al., 2008) histone methylation inferred from direct assay (Boulanger et al., 2004) peptidyl-arginine methylation, to asymmetrical-dimethyl arginine inferred from direct assay (Boulanger et al., 2004)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
protein-arginine N-methyltransferase activity inferred from sequence or structural similarity with UniProtKB:Q63009 (FlyBase, 1992-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
Art1 - CG10175 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Art1 - CG1129 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Art1 - CG1532 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Art1 - CG15343 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) Art1 - CG18081 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Art1 - CG2574 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) Art1 - CG4810 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Art1 - CG4813 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Art1 - CG7049 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Art1 - CSN4 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Art1 - Clc anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Art1 - CycY anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Art1 - Gen anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Art1 - GstD10 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Art1 - Hakai anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Art1 - Obp44a anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Art1 - Pabp2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Art1 - Prp18 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Art1 - Uev1A anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Art1 - fwe anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Art1 - gus anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Art1 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 66439 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0037834 DroID - A comprehensive database of gene and protein interactions. • FBgn0037834 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41295
Orthologs
OrthoDB Orthologs (55) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6CG0V7 Dipteran inclusive ortholog search EOG6R7VKH Insect inclusive ortholog search EOG6RJDX1 Arthropod inclusive ortholog search EOG6W6MBD Metazoa inclusive ortholog search EOG6ZD5XX
Orthologs in Drosophila Species (EOG6CG0V7)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Art1     Drosophila simulans   Dsim\GD20702 Y   Drosophila sechellia   Dsec\GM26148 Y   Drosophila erecta   Dere\GG17264 Y   Drosophila yakuba   Dyak\GE24666 Y   Drosophila ananassae   Dana\GF17088 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA19682 Y   Drosophila persimilis   Dper\GL21930 Y   Drosophila willistoni   Dwil\GK13389 Y   Drosophila virilis   Dvir\GJ10573 Y   Drosophila mojavensis   Dmoj\GI23860 Y   Drosophila grimshawi   Dgri\GH19565 Y
Orthologs in non-Drosophila Dipterans (EOG6R7VKH)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL003179   Anopheles gambiae Malaria mosquito  Agam\AGAP003462   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ003726
Orthologs in non-Dipteran Insects (EOG6RJDX1)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB42079   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG026499   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH10635   Atta cephalotes Leafcutter ant  Acep\ACEP10247   Camponotus floridanus Florida carpenter ant  Cflo\CFLO16735   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL19462   Linepithema humile Argentine ant  Lhum\LH12799   Pogonomyrmex barbatus Red harvester ant  Pbar\PB15457   Solenopsis invicta Red fire ant  Sinv\SINV17607   Acyrthosiphon pisum Pea aphid  Apim\ACYPI006777   Bombyx mori Silkmoth  Bmor\BGIBMGA004776   Pediculus humanus Human body louse  Phum\PHUM227250   Tribolium castaneum Red flour beetle  Tcas\TC009722
Orthologs in non-Insect Arthropods (EOG6W6MBD)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\MYH6   Daphnia pulex Water flea  Dpux\C1   Ixodes scapularis Deer tick  Isca\ISCW023973
Orthologs in non-Arthropod Metazoa (EOG6ZD5XX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\prmt-1 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_001244gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_019302gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_011712gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_023021gn Y Danio rerio Zebrafish  Drer\prmt1 Y Danio rerio Zebrafish  Drer\prmt3 Y Danio rerio Zebrafish  Drer\CABZ01016567.1 Y Danio rerio Zebrafish  Drer\prmt8b Y Xenopus tropicalis Western clawed frog  Xtro\prmt1 Y Xenopus tropicalis Western clawed frog  Xtro\prmt8 Y Xenopus tropicalis Western clawed frog  Xtro\prmt3 Y Gallus gallus Domestic chicken  Ggal\PRMT3 Y Gallus gallus Domestic chicken  Ggal\PRMT8 Y Mus musculus House mouse  Mmus\ENSMUSG00000030505 Y Mus musculus House mouse  Mmus\Prmt1 Y Mus musculus House mouse  Mmus\Prmt8 Y Rattus norvegicus Norway rat  Rnor\LOC100361025 Y Rattus norvegicus Norway rat  Rnor\Prmt3 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000038191 Y Rattus norvegicus Norway rat  Rnor\Prmt8 Y Homo sapiens Human  Hsap\PRMT3 Y Homo sapiens Human  Hsap\ENSG00000111218 Y Homo sapiens Human  Hsap\PRMT1 Y
Human Orthologs (3)
Gene OMIM HGNC Hsap\PRMT3     Hsap\ENSG00000111218     Hsap\PRMT1
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD20702 Drosophila sechellia Dsec\GM26148 Drosophila erecta Dere\GG17264 Drosophila yakuba Dyak\GE24666 Drosophila ananassae Dana\GF17088 Drosophila pseudoobscura pseudoobscura Dpse\GA19682 Drosophila persimilis Dper\GL21930 Drosophila willistoni Dwil\GK13389 Drosophila virilis Dvir\GJ10573 Drosophila mojavensis Dmoj\GI23860 Drosophila grimshawi Dgri\GH19565
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	31348 y1 v1; P{TRiP.JF01306}attP2 15202 y1; P{SUPor-P}Art1KG09631 ry506 36891 y1 sc* v1; P{TRiP.GL01072}attP2/TM3, Sb1
Kyoto	104065 w*; P{GawB}Art1NP2028 / TM3, Sb1 Ser1
VDRC	v40388 w1118 P{GD11959}v40388
Genomic Clones ( 3 )
	BACR15J23 BACR29B06 BACR32N16 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 232 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD28808
Other clones	DPiM_LD28808
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM04588 GM07555 GM23995 LD06267 LD07265 LD28748 LD38136 LD38221 LD40363 LP08876 LP10661 RE04044 RE14082 RE17025 RE18494 RE27162 RE31971 RE33922 RE37102 RE37165 RE39292 RE39709 RE40258 RE42936 RE45408 RE45466 RE45478 RE47244 RE49959 RE49960 RE54871 RE57641 RE61475 RE61861 RE68230 RE72266 RE72610 RE74029 SD01742 SD11492 SD11943 SD13807
Other clones	33602 41868 61437 61601 145787 146679 160245 190215 214315.43 273824 274918 275064 277268 281994 525724 CK01.32D.F3 CK01.85C.E3 CK01.113A.H1 CK01.123A.C11 Dmel_dig_009677_0652_1606 Dmel_dig_013369_0668_2810 Dmel_dig_014225_0699_2844 Dmel_neb_015684_0916_1084 EK038331 EK067718 EK093612 EK145704 EK174155 EK176407 EK185110 EK186746 EK249218 EK292438 EK302651 EK304015 EK307229 EN07024 FGH102E12 FGM222C09 FGM222D04 IP03203 IP03403 IP03503 IP07250 IP07350 IP07450 IP07550 RE01909 RE01976 RP003026895 RP003033315 RP003036309 RP003045655 RP003046567 RP003072620 RP003076404 RP003081063 RP003090776 RP003099352 RP003105268 RP003112021 RP003112820 RP003115398 RP003125033 RP003125778 RP003127049 RP003127493 RP003135627 RP003138273 RP003146032 RP003151336 RP003153470 RP003155457 RP003156108 RP003159063 RP003159792 RP003163307 RP003165862 RP003166804 RP003167108 RP003169701 RP003170838 RP003171114 RP003174022 RP003174645 RP003176772 RP003178053 RP003179165 RP003181354 RP003183742 RP003193172 RP003193265 RP003204095 RP003206088 RP003209780 RP003209803 RP003212003 RP003215351 RP003221899 RP003225132 RP003228461 RP003229041 RP003229699 RP003231474 RP003231765 RP003234051 RP003237222 RP003241131 RP003248328 RP003252324 RP003254835 RP003256749 RP003259448 RP003262221 RP003267582 RP003269487 RP003273412 RP003273705 RP003274484 RP003275514 RP003280366 RP003285110 RP003285721 RP003295076 RP003299150 RP003300707 RP003303420 RP003309226 RP003311989 RP003320064 RP003322446 RP003324044 RP003332484 RP003335536 RP003335870 RP003339321 RP003340919 RP003343326 RP003350622 RP003357273 RP003385590 RP003400927 RP003416595 RP003427387 RP003450281 RP003453746 RP003455994 RP003463184 RP003466469 RP003467462 RP003469557 RP003481686 RP003500498 RP003502212 RP003502263 RP003514187 RP003516272 RP003516601 RP003519108 RP003523380 RP003523545 RP003525390 RP003529132 RP003549455 RP003556828 RP003560206 RP003560243 RP003563521 RP003581732 RP003585813 RP003593271 RP003614488 RP003621346 RP003626420 RP003630148 RP003631382 RP003634610 RP003641451 RP003651331 RP003653645 RP003656936 RP003656952 RP003660987 RP003662716 RP003667024 RP003671521 RP003678022 RP003678907
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0037834 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41295
Antibody Information
	polyclonal (Boulanger et al., 2004)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_141760 RefSeq (Proteins) • NP_650017 DDBJ / EMBL / GenBank • AA950295 AAF54556 AAM11369 AW942908 AY095041 BZ665699 Entrez Gene - A searchable database of RefSeq genes. • 41295 UniProtKB/TrEMBL • Q9VGW7
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Protein arginine N-methyltransferase (IPR025799) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD28808
Linkouts
	BioGRID - A database of protein and genetic interactions • 66439 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0037834 DroID - A comprehensive database of gene and protein interactions. • FBgn0037834 DRSC - Results from RNAi screens. • FBgn0037834 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037834 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6554-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0037834 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41295 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41295 modMine - Data generated by the modENCODE project. • FBgn0037834
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	Art1 (Gan et al., 2010, Lake et al., 2007) CG6554 (Ni et al., 2011.7.19, Ni et al., 2008, Keleman et al., 2009.8.5, Cammarato et al., 2011) DART1 (Boulanger et al., 2004, Kimura et al., 2008)
Name Synonym	Arginine methyltransferase 1 (Boulanger et al., 2004, Cammarato et al., 2011) arginine methyltransferase 1 (Kimura et al., 2008)
Secondary FlyBase IDs
References ( 28 )
Generate a list of	All references relating to this gene ( 28 )
List References by type	Research paper  ( 6 ) Supplementary material  ( 6 ) Personal communication to FlyBase  ( 10 ) Abstract  ( 1 ) FlyBase analysis  ( 2 ) Website  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...