• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\CG6567

General Information
Symbol	Dmel\CG6567	Species	D. melanogaster
Name		Annotation symbol	CG6567
Feature type	protein_coding_gene	FlyBase ID	FBgn0037842
Gene Model Status	Current	Stock availability	8 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	86C7-86C7	Sequence location	3R:6,679,096..6,680,173 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG6567 (FBgn0037842). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: lysophospholipase activity. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Phospholipase/carboxylesterase/thioesterase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1630131_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG6567. Gene sequence location is 3R:6679096..6680173.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 86C7-86C7   Limits computationally determined from genome sequence between P{PZ}hth05745 and P{EP}EP3340EP3340
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG6567 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.47
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG6567-RB FBtr0113217  NM_001104272   1017   235
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG6567-PB   FBpp0112129   26.2   235   8.43     NP_001097742   AAF54564
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Phospholipase/carboxylesterase/thioesterase (IPR003140)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF54564   AI114272   AI134228   AI402242   AY102661 AAM27490   BI566066   BI587970   BI588731   BI630912   CO195453   CO283840   CO311386   CO313174   CO313180   CZ474129   EC063055   EC065205   EC076236   EC248496   GH830321
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VGV9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    135.575 Larval Midgut    243 Larval Hindgut    154.9 Larval Malpighian Tubules    310.6 Larval Fat Body    258.5 Larval Salivary Gland    248.6 Larval Trachea    146.6 Larval Carcass    128.625 Adult Head    143.3 Adult Eye    83.875 Adult Brain    77.5 Adult Thoracic-Abdominal Ganglion    57.8 Adult Crop    256.9 Adult Midgut    243.5 Adult Hindgut    131.9 Adult Malpighian Tubules    114.9 Adult Fat Body    315.1 Adult Salivary Gland    122.6 Adult Heart    235.525 Adult VirginFemale Spermatheca    124.9 Adult InseminatedFemale Spermatheca    109.7 Adult Ovary    202.5 Adult Testis    91.1 Adult Male Accessory Gland    78.3 Adult Carcass    203.6 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    135.575 Larval Midgut    243 Larval Hindgut    154.9 Larval Malpighian Tubules    310.6 Larval Fat Body    258.5 Larval Salivary Gland    248.6 Larval Trachea    146.6 Larval Carcass    128.625 Adult Head    143.3 Adult Eye    83.875 Adult Brain    77.5 Adult Thoracic-Abdominal Ganglion    57.8 Adult Crop    256.9 Adult Midgut    243.5 Adult Hindgut    131.9 Adult Malpighian Tubules    114.9 Adult Fat Body    315.1 Adult Salivary Gland    122.6 Adult Heart    235.525 Adult VirginFemale Spermatheca    124.9 Adult InseminatedFemale Spermatheca    109.7 Adult Ovary    202.5 Adult Testis    91.1 Adult Male Accessory Gland    78.3 Adult Carcass    203.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    135.575 Larval Midgut    243 Larval Hindgut    154.9 Larval Malpighian Tubules    310.6 Larval Fat Body    258.5 Larval Salivary Gland    248.6 Larval Trachea    146.6 Larval Carcass    128.625 Adult Head    143.3 Adult Eye    83.875 Adult Brain    77.5 Adult Thoracic-Abdominal Ganglion    57.8 Adult Crop    256.9 Adult Midgut    243.5 Adult Hindgut    131.9 Adult Malpighian Tubules    114.9 Adult Fat Body    315.1 Adult Salivary Gland    122.6 Adult Heart    235.525 Adult VirginFemale Spermatheca    124.9 Adult InseminatedFemale Spermatheca    109.7 Adult Ovary    202.5 Adult Testis    91.1 Adult Male Accessory Gland    78.3 Adult Carcass    203.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    135.575 Larval Midgut    243 Larval Hindgut    154.9 Larval Malpighian Tubules    310.6 Larval Fat Body    258.5 Larval Salivary Gland    248.6 Larval Trachea    146.6 Larval Carcass    128.625 Adult Head    143.3 Adult Eye    83.875 Adult Brain    77.5 Adult Thoracic-Abdominal Ganglion    57.8 Adult Crop    256.9 Adult Midgut    243.5 Adult Hindgut    131.9 Adult Malpighian Tubules    114.9 Adult Fat Body    315.1 Adult Salivary Gland    122.6 Adult Heart    235.525 Adult VirginFemale Spermatheca    124.9 Adult InseminatedFemale Spermatheca    109.7 Adult Ovary    202.5 Adult Testis    91.1 Adult Male Accessory Gland    78.3 Adult Carcass    203.6 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    135.575 Larval Midgut    243 Larval Hindgut    154.9 Larval Malpighian Tubules    310.6 Larval Fat Body    258.5 Larval Salivary Gland    248.6 Larval Trachea    146.6 Larval Carcass    128.625 Adult Head    143.3 Adult Eye    83.875 Adult Brain    77.5 Adult Thoracic-Abdominal Ganglion    57.8 Adult Crop    256.9 Adult Midgut    243.5 Adult Hindgut    131.9 Adult Malpighian Tubules    114.9 Adult Fat Body    315.1 Adult Salivary Gland    122.6 Adult Heart    235.525 Adult VirginFemale Spermatheca    124.9 Adult InseminatedFemale Spermatheca    109.7 Adult Ovary    202.5 Adult Testis    91.1 Adult Male Accessory Gland    78.3 Adult Carcass    203.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    135.575 Larval Midgut    243 Larval Hindgut    154.9 Larval Malpighian Tubules    310.6 Larval Fat Body    258.5 Larval Salivary Gland    248.6 Larval Trachea    146.6 Larval Carcass    128.625 Adult Head    143.3 Adult Eye    83.875 Adult Brain    77.5 Adult Thoracic-Abdominal Ganglion    57.8 Adult Crop    256.9 Adult Midgut    243.5 Adult Hindgut    131.9 Adult Malpighian Tubules    114.9 Adult Fat Body    315.1 Adult Salivary Gland    122.6 Adult Heart    235.525 Adult VirginFemale Spermatheca    124.9 Adult InseminatedFemale Spermatheca    109.7 Adult Ovary    202.5 Adult Testis    91.1 Adult Male Accessory Gland    78.3 Adult Carcass    203.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    135.575 Larval Midgut    243 Larval Hindgut    154.9 Larval Malpighian Tubules    310.6 Larval Fat Body    258.5 Larval Salivary Gland    248.6 Larval Trachea    146.6 Larval Carcass    128.625 Adult Head    143.3 Adult Eye    83.875 Adult Brain    77.5 Adult Thoracic-Abdominal Ganglion    57.8 Adult Crop    256.9 Adult Midgut    243.5 Adult Hindgut    131.9 Adult Malpighian Tubules    114.9 Adult Fat Body    315.1 Adult Salivary Gland    122.6 Adult Heart    235.525 Adult VirginFemale Spermatheca    124.9 Adult InseminatedFemale Spermatheca    109.7 Adult Ovary    202.5 Adult Testis    91.1 Adult Male Accessory Gland    78.3 Adult Carcass    203.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    135.575 Larval Midgut    243 Larval Hindgut    154.9 Larval Malpighian Tubules    310.6 Larval Fat Body    258.5 Larval Salivary Gland    248.6 Larval Trachea    146.6 Larval Carcass    128.625 Adult Head    143.3 Adult Eye    83.875 Adult Brain    77.5 Adult Thoracic-Abdominal Ganglion    57.8 Adult Crop    256.9 Adult Midgut    243.5 Adult Hindgut    131.9 Adult Malpighian Tubules    114.9 Adult Fat Body    315.1 Adult Salivary Gland    122.6 Adult Heart    235.525 Adult VirginFemale Spermatheca    124.9 Adult InseminatedFemale Spermatheca    109.7 Adult Ovary    202.5 Adult Testis    91.1 Adult Male Accessory Gland    78.3 Adult Carcass    203.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    143.3   NA  Eye    83.875   NA  Brain    77.5   135.575  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    57.8   NA  Crop    256.9   243  Midgut    243.5   154.9  Hindgut    131.9   310.6  Malpighian Tubules    114.9   258.5  Fat Body    315.1   248.6  Salivary Gland    122.6   NA  Heart    235.525   146.6  Trachea    NA   NA  VirginFemale Spermatheca    124.9   NA  InseminatedFemale Spermatheca    109.7   NA  Ovary    202.5   NA  Testis    91.1   NA  Male Accessory Gland    78.3   128.625  Carcass    203.6 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    17 central nervous system, pupae P8    12 head, virgin 1-day female    14 head, virgin 4-day female    8 head, virgin 20-day female    14 head, mated 1-day female    12 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    10 head, mated 4-day male    14 head, mated 20-day male    17 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    17 digestive system, 1-day adult    24 digestive system, 4-day adult    20 digestive system, 20-day adult    14 fat body, larvae L3 wandering    19 fat body, white prepupae    15 fat body, pupae P8    11 carcass, larvae L3 wandering    11 carcass, 1-day adult    18 carcass, 4-day adult    20 carcass, 20-day adult    15 ovary, virgin 4-day female    41 ovary, mated 4-day female    26 testis, mated 4-day male    24 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    17 central nervous system, pupae P8    12 head, virgin 1-day female    14 head, virgin 4-day female    8 head, virgin 20-day female    14 head, mated 1-day female    12 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    10 head, mated 4-day male    14 head, mated 20-day male    17 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    17 digestive system, 1-day adult    24 digestive system, 4-day adult    20 digestive system, 20-day adult    14 fat body, larvae L3 wandering    19 fat body, white prepupae    15 fat body, pupae P8    11 carcass, larvae L3 wandering    11 carcass, 1-day adult    18 carcass, 4-day adult    20 carcass, 20-day adult    15 ovary, virgin 4-day female  (41) ovary, mated 4-day female  26 testis, mated 4-day male    24 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    17 central nervous system, pupae P8    12 head, virgin 1-day female    14 head, virgin 4-day female    8 head, virgin 20-day female    14 head, mated 1-day female    12 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    10 head, mated 4-day male    14 head, mated 20-day male    17 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    17 digestive system, 1-day adult    24 digestive system, 4-day adult    20 digestive system, 20-day adult    14 fat body, larvae L3 wandering    19 fat body, white prepupae    15 fat body, pupae P8    11 carcass, larvae L3 wandering    11 carcass, 1-day adult    18 carcass, 4-day adult    20 carcass, 20-day adult    15 ovary, virgin 4-day female    41 ovary, mated 4-day female    26 testis, mated 4-day male    24 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    17 central nervous system, pupae P8    12 head, virgin 1-day female    14 head, virgin 4-day female    8 head, virgin 20-day female    14 head, mated 1-day female    12 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    10 head, mated 4-day male    14 head, mated 20-day male    17 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    17 digestive system, 1-day adult    24 digestive system, 4-day adult    20 digestive system, 20-day adult    14 fat body, larvae L3 wandering    19 fat body, white prepupae    15 fat body, pupae P8    11 carcass, larvae L3 wandering    11 carcass, 1-day adult    18 carcass, 4-day adult    20 carcass, 20-day adult    15 ovary, virgin 4-day female    41 ovary, mated 4-day female    26 testis, mated 4-day male    24 accessory gland, mated 4-day male    16 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    17 central nervous system, pupae P8    12 head, virgin 1-day female    14 head, virgin 4-day female    8 head, virgin 20-day female    14 head, mated 1-day female    12 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    10 head, mated 4-day male    14 head, mated 20-day male    17 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    17 digestive system, 1-day adult    24 digestive system, 4-day adult    20 digestive system, 20-day adult    14 fat body, larvae L3 wandering    19 fat body, white prepupae    15 fat body, pupae P8    11 carcass, larvae L3 wandering    11 carcass, 1-day adult    18 carcass, 4-day adult    20 carcass, 20-day adult    15 ovary, virgin 4-day female    41 ovary, mated 4-day female    26 testis, mated 4-day male    24 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    17 central nervous system, pupae P8    12 head, virgin 1-day female    14 head, virgin 4-day female    8 head, virgin 20-day female    14 head, mated 1-day female    12 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    10 head, mated 4-day male    14 head, mated 20-day male    17 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    17 digestive system, 1-day adult    24 digestive system, 4-day adult    20 digestive system, 20-day adult    14 fat body, larvae L3 wandering    19 fat body, white prepupae    15 fat body, pupae P8    11 carcass, larvae L3 wandering    11 carcass, 1-day adult    18 carcass, 4-day adult    20 carcass, 20-day adult    15 ovary, virgin 4-day female  (41) ovary, mated 4-day female  26 testis, mated 4-day male    24 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    17 central nervous system, pupae P8    12 head, virgin 1-day female    14 head, virgin 4-day female    8 head, virgin 20-day female    14 head, mated 1-day female    12 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    10 head, mated 4-day male    14 head, mated 20-day male    17 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    17 digestive system, 1-day adult    24 digestive system, 4-day adult    20 digestive system, 20-day adult    14 fat body, larvae L3 wandering    19 fat body, white prepupae    15 fat body, pupae P8    11 carcass, larvae L3 wandering    11 carcass, 1-day adult    18 carcass, 4-day adult    20 carcass, 20-day adult    15 ovary, virgin 4-day female    41 ovary, mated 4-day female    26 testis, mated 4-day male    24 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    17 central nervous system, pupae P8    12 head, virgin 1-day female    14 head, virgin 4-day female    8 head, virgin 20-day female    14 head, mated 1-day female    12 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    10 head, mated 4-day male    14 head, mated 20-day male    17 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    17 digestive system, 1-day adult    24 digestive system, 4-day adult    20 digestive system, 20-day adult    14 fat body, larvae L3 wandering    19 fat body, white prepupae    15 fat body, pupae P8    11 carcass, larvae L3 wandering    11 carcass, 1-day adult    18 carcass, 4-day adult    20 carcass, 20-day adult    15 ovary, virgin 4-day female    41 ovary, mated 4-day female    26 testis, mated 4-day male    24 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    32 embryo 02-04hr    6 embryo 04-06hr    16 embryo 06-08hr    23 embryo 08-10hr    16 embryo 10-12hr    20 embryo 12-14hr    20 embryo 14-16hr    19 embryo 16-18hr    19 embryo 18-20hr    18 embryo 20-22hr    17 embryo 22-24hr    20 larva L1    38 larva L2    42 larva L3 12hr old    37 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    21 white prepupae new    19 white prepupae 12hr    18 white prepupae 24hr    20 pupae 2d postWPP    17 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    17 adult male 05day    18 adult male 30day    17 adult female 01day    26 adult female 05day    34 adult female 30day    38 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (32) embryo 02-04hr    6 embryo 04-06hr    16 embryo 06-08hr    23 embryo 08-10hr    16 embryo 10-12hr    20 embryo 12-14hr    20 embryo 14-16hr    19 embryo 16-18hr    19 embryo 18-20hr    18 embryo 20-22hr    17 embryo 22-24hr    20 larva L1  (38) larva L2  (42) larva L3 12hr old  (37) larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    21 white prepupae new    19 white prepupae 12hr    18 white prepupae 24hr    20 pupae 2d postWPP    17 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    17 adult male 05day    18 adult male 30day    17 adult female 01day  26 adult female 05day  (34) adult female 30day  (38) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    32 embryo 02-04hr    6 embryo 04-06hr    16 embryo 06-08hr    23 embryo 08-10hr    16 embryo 10-12hr    20 embryo 12-14hr    20 embryo 14-16hr    19 embryo 16-18hr    19 embryo 18-20hr    18 embryo 20-22hr    17 embryo 22-24hr    20 larva L1    38 larva L2    42 larva L3 12hr old    37 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    21 white prepupae new    19 white prepupae 12hr    18 white prepupae 24hr    20 pupae 2d postWPP    17 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    17 adult male 05day    18 adult male 30day    17 adult female 01day    26 adult female 05day    34 adult female 30day    38 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    32 embryo 02-04hr    6 embryo 04-06hr    16 embryo 06-08hr    23 embryo 08-10hr    16 embryo 10-12hr    20 embryo 12-14hr    20 embryo 14-16hr    19 embryo 16-18hr    19 embryo 18-20hr    18 embryo 20-22hr    17 embryo 22-24hr    20 larva L1    38 larva L2    42 larva L3 12hr old    37 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    21 white prepupae new    19 white prepupae 12hr    18 white prepupae 24hr    20 pupae 2d postWPP    17 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    17 adult male 05day    18 adult male 30day    17 adult female 01day    26 adult female 05day    34 adult female 30day    38 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    32 embryo 02-04hr    6 embryo 04-06hr    16 embryo 06-08hr    23 embryo 08-10hr    16 embryo 10-12hr    20 embryo 12-14hr    20 embryo 14-16hr    19 embryo 16-18hr    19 embryo 18-20hr    18 embryo 20-22hr    17 embryo 22-24hr    20 larva L1    38 larva L2    42 larva L3 12hr old    37 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    21 white prepupae new    19 white prepupae 12hr    18 white prepupae 24hr    20 pupae 2d postWPP    17 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    17 adult male 05day    18 adult male 30day    17 adult female 01day    26 adult female 05day    34 adult female 30day    38 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  32 embryo 02-04hr    6 embryo 04-06hr    16 embryo 06-08hr    23 embryo 08-10hr    16 embryo 10-12hr    20 embryo 12-14hr    20 embryo 14-16hr    19 embryo 16-18hr    19 embryo 18-20hr    18 embryo 20-22hr    17 embryo 22-24hr    20 larva L1  (38) larva L2  (42) larva L3 12hr old  (37) larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    21 white prepupae new    19 white prepupae 12hr    18 white prepupae 24hr    20 pupae 2d postWPP    17 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    17 adult male 05day    18 adult male 30day    17 adult female 01day  26 adult female 05day  (34) adult female 30day  (38) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    32 embryo 02-04hr    6 embryo 04-06hr    16 embryo 06-08hr    23 embryo 08-10hr    16 embryo 10-12hr    20 embryo 12-14hr    20 embryo 14-16hr    19 embryo 16-18hr    19 embryo 18-20hr    18 embryo 20-22hr    17 embryo 22-24hr    20 larva L1    38 larva L2    42 larva L3 12hr old    37 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    21 white prepupae new    19 white prepupae 12hr    18 white prepupae 24hr    20 pupae 2d postWPP    17 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    17 adult male 05day    18 adult male 30day    17 adult female 01day    26 adult female 05day    34 adult female 30day    38 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    32 embryo 02-04hr    6 embryo 04-06hr    16 embryo 06-08hr    23 embryo 08-10hr    16 embryo 10-12hr    20 embryo 12-14hr    20 embryo 14-16hr    19 embryo 16-18hr    19 embryo 18-20hr    18 embryo 20-22hr    17 embryo 22-24hr    20 larva L1    38 larva L2    42 larva L3 12hr old    37 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    21 white prepupae new    19 white prepupae 12hr    18 white prepupae 24hr    20 pupae 2d postWPP    17 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    17 adult male 05day    18 adult male 30day    17 adult female 01day    26 adult female 05day    34 adult female 30day    38 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    40 Schneider line 2 Sg4    42 embryonic 1182-4H    23 embryonic GM2    48 embryonic Kc167    26 embryonic S1    20 embryonic S3    25 leg disc CME L1    30 wing disc CME-W2    34 wing disc ML-DmD8    24 wing disc ML-DmD9    18 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    31 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    30 eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5    39 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    20 tumorous blood cells mbn2    16 ovary fGS/OSS    12 ovary OSC    12 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (40) Schneider line 2 Sg4  (42) embryonic 1182-4H    23 embryonic GM2  (48) embryonic Kc167  26 embryonic S1    20 embryonic S3    25 leg disc CME L1  (30) wing disc CME-W2  (34) wing disc ML-DmD8    24 wing disc ML-DmD9    18 wing disc ML-DmD16-c3    17 wing disc ML-DmD21  (31) wing disc ML-DmD32    23 haltere disc ML-DmD17-c3  (30) eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5  (39) mixed discs ML-DmD4-c1  (30) CNS ML-DmBG1-c1  (27) CNS ML-DmBG2-c2    20 tumorous blood cells mbn2    16 ovary fGS/OSS    12 ovary OSC    12 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    40 Schneider line 2 Sg4    42 embryonic 1182-4H    23 embryonic GM2    48 embryonic Kc167    26 embryonic S1    20 embryonic S3    25 leg disc CME L1    30 wing disc CME-W2    34 wing disc ML-DmD8    24 wing disc ML-DmD9    18 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    31 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    30 eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5    39 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    20 tumorous blood cells mbn2    16 ovary fGS/OSS    12 ovary OSC    12 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    40 Schneider line 2 Sg4    42 embryonic 1182-4H    23 embryonic GM2    48 embryonic Kc167    26 embryonic S1    20 embryonic S3    25 leg disc CME L1    30 wing disc CME-W2    34 wing disc ML-DmD8    24 wing disc ML-DmD9    18 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    31 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    30 eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5    39 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    20 tumorous blood cells mbn2    16 ovary fGS/OSS    12 ovary OSC    12 ovary OSS    6 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    40 Schneider line 2 Sg4    42 embryonic 1182-4H    23 embryonic GM2    48 embryonic Kc167    26 embryonic S1    20 embryonic S3    25 leg disc CME L1    30 wing disc CME-W2    34 wing disc ML-DmD8    24 wing disc ML-DmD9    18 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    31 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    30 eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5    39 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    20 tumorous blood cells mbn2    16 ovary fGS/OSS    12 ovary OSC    12 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (40) Schneider line 2 Sg4  (42) embryonic 1182-4H    23 embryonic GM2  (48) embryonic Kc167  26 embryonic S1    20 embryonic S3    25 leg disc CME L1  30 wing disc CME-W2  (34) wing disc ML-DmD8    24 wing disc ML-DmD9    18 wing disc ML-DmD16-c3    17 wing disc ML-DmD21  31 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3  30 eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5  (39) mixed discs ML-DmD4-c1  30 CNS ML-DmBG1-c1  27 CNS ML-DmBG2-c2    20 tumorous blood cells mbn2    16 ovary fGS/OSS    12 ovary OSC    12 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    40 Schneider line 2 Sg4    42 embryonic 1182-4H    23 embryonic GM2    48 embryonic Kc167    26 embryonic S1    20 embryonic S3    25 leg disc CME L1    30 wing disc CME-W2    34 wing disc ML-DmD8    24 wing disc ML-DmD9    18 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    31 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    30 eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5    39 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    20 tumorous blood cells mbn2    16 ovary fGS/OSS    12 ovary OSC    12 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    40 Schneider line 2 Sg4    42 embryonic 1182-4H    23 embryonic GM2    48 embryonic Kc167    26 embryonic S1    20 embryonic S3    25 leg disc CME L1    30 wing disc CME-W2    34 wing disc ML-DmD8    24 wing disc ML-DmD9    18 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    31 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    30 eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5    39 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    20 tumorous blood cells mbn2    16 ovary fGS/OSS    12 ovary OSC    12 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    5 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    33 Cadmium 50 mM 12 hrs, larvae L3    27 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult    25 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    21 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    39 Ethanol 10% 3 hrs, larvae L3    27 Caffeine 1.5 mg/ml 4 hrs, larvae L3    31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    19 Rotenone 2 μg 12 hrs, larvae L3    34 Rotenone 8 μg 12 hrs, larvae L3    25 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    5 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3  (33) Cadmium 50 mM 12 hrs, larvae L3  (27) Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult    25 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    21 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3  (39) Ethanol 10% 3 hrs, larvae L3  (27) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (31) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult  26 Paraquat 10 mM 48 hrs, 4-day adult    19 Rotenone 2 μg 12 hrs, larvae L3  (34) Rotenone 8 μg 12 hrs, larvae L3    25 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    5 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    33 Cadmium 50 mM 12 hrs, larvae L3    27 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult    25 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    21 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    39 Ethanol 10% 3 hrs, larvae L3    27 Caffeine 1.5 mg/ml 4 hrs, larvae L3    31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    19 Rotenone 2 μg 12 hrs, larvae L3    34 Rotenone 8 μg 12 hrs, larvae L3    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    5 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    33 Cadmium 50 mM 12 hrs, larvae L3    27 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult    25 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    21 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    39 Ethanol 10% 3 hrs, larvae L3    27 Caffeine 1.5 mg/ml 4 hrs, larvae L3    31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    19 Rotenone 2 μg 12 hrs, larvae L3    34 Rotenone 8 μg 12 hrs, larvae L3    25 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    5 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    33 Cadmium 50 mM 12 hrs, larvae L3    27 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult    25 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    21 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    39 Ethanol 10% 3 hrs, larvae L3    27 Caffeine 1.5 mg/ml 4 hrs, larvae L3    31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    19 Rotenone 2 μg 12 hrs, larvae L3    34 Rotenone 8 μg 12 hrs, larvae L3    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    5 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3  (33) Cadmium 50 mM 12 hrs, larvae L3  27 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult    25 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    21 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3  (39) Ethanol 10% 3 hrs, larvae L3  27 Caffeine 1.5 mg/ml 4 hrs, larvae L3  31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult  26 Paraquat 10 mM 48 hrs, 4-day adult    19 Rotenone 2 μg 12 hrs, larvae L3  (34) Rotenone 8 μg 12 hrs, larvae L3    25 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    5 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    33 Cadmium 50 mM 12 hrs, larvae L3    27 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult    25 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    21 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    39 Ethanol 10% 3 hrs, larvae L3    27 Caffeine 1.5 mg/ml 4 hrs, larvae L3    31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    19 Rotenone 2 μg 12 hrs, larvae L3    34 Rotenone 8 μg 12 hrs, larvae L3    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    5 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    33 Cadmium 50 mM 12 hrs, larvae L3    27 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult    25 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    21 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    39 Ethanol 10% 3 hrs, larvae L3    27 Caffeine 1.5 mg/ml 4 hrs, larvae L3    31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    19 Rotenone 2 μg 12 hrs, larvae L3    34 Rotenone 8 μg 12 hrs, larvae L3    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_26 mE1_20_mRNA_expression_cluster_05
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037842 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6567-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG6567d09306 viable, with Scer\GAL4pnr-MD237 CG6567GD11964 Sterility Allele fertile CG6567d09306 Phenotype manifest in Allele
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of CG6567 Class Mutagen Stocks Known lesion CG6567d09306 P-element activity 2 -- CG6567d04782 P-element activity 1 -- CG6567f06981 1 -- CG6567MI01214 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG6567 Class Mutagen Stocks Known lesion CG6567GD11964 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG6567KK101564 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG6567NIG.6567R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6159 (Ryder, 2004.4.26) Df(3R)Exel7305 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD11964} NA P{KK101564} NA P{NIG.6567R} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions Mi{MIC}CG4565MI01214 NA P{Switch2}GSG3473 NA PBac{WH}CG6567f06981 NA insertion of mobile activating element P{XP}CG6567d04782 NA P{XP}CG6567d09306 NA
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
lysophospholipase activity inferred from sequence or structural similarity with EMBL:U89352 (FlyBase, 1992-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG6567 - Ppt2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG6567 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 66448 DroID - A comprehensive database of gene and protein interactions. • FBgn0037842 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41304
Orthologs
OrthoDB Orthologs (34) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6T78PP Dipteran inclusive ortholog search EOG618BXH Insect inclusive ortholog search EOG6DND1N Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search EOG6PKF3G
Orthologs in Drosophila Species (EOG6T78PP)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG6567     Drosophila simulans   Dsim\GD20698 Y   Drosophila sechellia   Dsec\GM26145 Y   Drosophila erecta   Dere\GG17261 Y   Drosophila yakuba   Dyak\GE24662 Y   Drosophila ananassae   Dana\GF17085 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA19689 Y   Drosophila persimilis   Dper\GL21926 Y   Drosophila willistoni   Dwil\GK13386 Y   Drosophila virilis   Dvir\GJ10571 Y   Drosophila mojavensis   Dmoj\GI23857 Y   Drosophila grimshawi   Dgri\GH19562 Y
Orthologs in non-Drosophila Dipterans (EOG618BXH)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL003895   Anopheles gambiae Malaria mosquito  Agam\AGAP012883   Anopheles gambiae Malaria mosquito  Agam\AGAP004271   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ003610
Orthologs in non-Dipteran Insects (EOG6DND1N)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC725796   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013268   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH11386   Atta cephalotes Leafcutter ant  Acep\ACEP16040   Camponotus floridanus Florida carpenter ant  Cflo\CFLO19977   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL14939   Linepithema humile Argentine ant  Lhum\LH18555   Pogonomyrmex barbatus Red harvester ant  Pbar\PB17757   Solenopsis invicta Red fire ant  Sinv\SINV11046   Bombyx mori Silkmoth  Bmor\BGIBMGA000506   Tribolium castaneum Red flour beetle  Tcas\GLEAN_08421
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (EOG6PKF3G)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_003712gn   Danio rerio Zebrafish  Drer\zgc:110848   Xenopus tropicalis Western clawed frog  Xtro\lyplal1   Gallus gallus Domestic chicken  Ggal\LYPLAL1   Mus musculus House mouse  Mmus\Lyplal1   Rattus norvegicus Norway rat  Rnor\Lyplal1   Homo sapiens Human  Hsap\LYPLAL1
Human Orthologs (1)
Gene OMIM HGNC Hsap\LYPLAL1
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD20698 Drosophila sechellia Dsec\GM26145 Drosophila erecta Dere\GG17261 Drosophila yakuba Dyak\GE24662 Drosophila ananassae Dana\GF17085 Drosophila pseudoobscura pseudoobscura Dpse\GA19689 Drosophila persimilis Dper\GL21926 Drosophila willistoni Dwil\GK13386 Drosophila virilis Dvir\GJ10571 Drosophila mojavensis Dmoj\GI23857 Drosophila grimshawi Dgri\GH19562
Stocks & Reagents
Stocks Listed in FlyBase ( 8 )
Bloomington	19313 w1118; P{XP}CG6567d09306 34409 y1 w*; Mi{MIC}CG4565MI01214 CG6567MI01214
Harvard	- P{XP}CG6567d04782 - P{XP}CG6567d09306 - PBac{WH}CG6567f06981
VDRC	v108592 P{KK101564}VIE-260B v27666 w1118; P{GD11964}v27666 v27667 w1118; P{GD11964}v27667
Genomic Clones ( 2 )
	BACR15J23 BACR32N16 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 16 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH11067
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH11625 RH28912 RH30141 RH35168 RH60256
Other clones	62153 102096 106558 106562 EC40382 EK164543 EK224333 EK231814 EK231822 RP003360876
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0037842 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41304
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_001104272 RefSeq (Proteins) • NP_001097742 DDBJ / EMBL / GenBank • AAF54564 AAM27490 AI114272 AI402242 AY102661 CZ474129 Entrez Gene - A searchable database of RefSeq genes. • 41304 UniProtKB/TrEMBL • Q9VGV9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Phospholipase/carboxylesterase/thioesterase (IPR003140)
Linkouts
	BioGRID - A database of protein and genetic interactions • 66448 DroID - A comprehensive database of gene and protein interactions. • FBgn0037842 DRSC - Results from RNAi screens. • FBgn0037842 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037842 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6567-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0037842 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41304 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41304 modMine - Data generated by the modENCODE project. • FBgn0037842
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG6567 (Nicholson et al., 2008, Keleman et al., 2009.8.5, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym
Secondary FlyBase IDs
References ( 18 )
Research paper	Nicholson et al., 2008, Genetics 178(1): 215--234 Spatial and temporal control of gene expression in Drosophila using the inducible GeneSwitch GAL4 System. I. Screen for larval nervous system drivers. [FBrf0202785]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Bellen, 2011.2.28, set926.xml set926.xml [FBrf0213112] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file) Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]
Curated genome annotation	Find Enzymes, 1999.11, [Automatic annotations performed at the Celera Jamboreee.] [Automatic annotations performed at the Celera Jamboreee.] [FBrf0126664]