Gene Dmel\CG17734

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General Information

Symbol

Dmel\CG17734

Species

D. melanogaster

Name

Annotation symbol

CG17734

Feature type

protein_coding_gene

FlyBase ID

FBgn0037890

Gene Model Status

Current

Stock availability

10 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

86D8-86D9

Sequence location

3R:7,067,930..7,069,721 [-]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG17734 (FBgn0037890). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: behavioral response to ethanol. 12 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Hypoxia induced protein, domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 18-24 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval fat body, adult testis. Gene sequence location is 3R:7067930..7069721.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

86D8-86D9

Limits computationally determined from genome sequence between P{EP}EP3340^EP3340 and P{PZ}tho¹&P{PZ}l(3)04629⁰⁵²⁷⁵

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG17734 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.49

Low-frequency RNA-Seq exon junction(s) not annotated.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG17734-RA

FBtr0082360

NM_141806

764

101

FBtr0082361

1024

FBtr0308073

1317

106

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG17734-PA

FBpp0081836

10.9

101

10.01

NP_650063

AAF54624

CG17734-PB

FBpp0081837

10.3

10.01

NP_731561

AAN13498

CG17734-PC

FBpp0300416

11.8

106

6.50

NP_001247043

AFH06361

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Hypoxia induced protein, domain (IPR007667)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

(Fisher et al., 2012)

Comment:maternally deposited

embryonic stage 4 -- 6

organism

(Fisher et al., 2012)

Comment:rapidly degraded

pole cell

(Fisher et al., 2012)

embryonic stage 7 -- 8

pole cell

(Fisher et al., 2012)

embryonic stage 9 -- 10

germline cell

(Fisher et al., 2012)

embryonic stage 11 -- 12

germline cell

(Fisher et al., 2012)

embryonic stage 13 -- 16

germline cell

(Fisher et al., 2012)

gonad

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

day 7 of adulthood -- day 49 of adulthood

adult heart

(Cammarato et al., 2011)

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval fat body, adult testis.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		20
central nervous system, larvae L3		12
central nervous system, pupae P8		5
head, virgin 1-day female		48
head, virgin 4-day female		26
head, virgin 20-day female		40
head, mated 1-day female		32
head, mated 4-day female		42
head, mated 20-day female		29
head, mated 1-day male		43
head, mated 4-day male		41
head, mated 20-day male		41
salivary gland, larvae L3 wandering		5
salivary gland, white prepupae		21
digestive system, larvae L3 wandering		18
digestive system, 1-day adult		59
digestive system, 4-day adult		48
digestive system, 20-day adult		40
fat body, larvae L3 wandering		8
fat body, white prepupae		9
fat body, pupae P8		11
carcass, larvae L3 wandering		10
carcass, 1-day adult		60
carcass, 4-day adult		51
carcass, 20-day adult		35
ovary, virgin 4-day female		72
ovary, mated 4-day female		54
testis, mated 4-day male		13
accessory gland, mated 4-day male		11
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		20
central nervous system, larvae L3		12
central nervous system, pupae P8		5
head, virgin 1-day female		(48)
head, virgin 4-day female		26
head, virgin 20-day female		(40)
head, mated 1-day female		(32)
head, mated 4-day female		(42)
head, mated 20-day female		(29)
head, mated 1-day male		(43)
head, mated 4-day male		(41)
head, mated 20-day male		(41)
salivary gland, larvae L3 wandering		5
salivary gland, white prepupae		21
digestive system, larvae L3 wandering		18
digestive system, 1-day adult		(59)
digestive system, 4-day adult		(48)
digestive system, 20-day adult		(40)
fat body, larvae L3 wandering		8
fat body, white prepupae		9
fat body, pupae P8		11
carcass, larvae L3 wandering		10
carcass, 1-day adult		(60)
carcass, 4-day adult		(51)
carcass, 20-day adult		(35)
ovary, virgin 4-day female		(72)
ovary, mated 4-day female		(54)
testis, mated 4-day male		13
accessory gland, mated 4-day male		11
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		20
central nervous system, larvae L3		12
central nervous system, pupae P8		5
head, virgin 1-day female		48
head, virgin 4-day female		26
head, virgin 20-day female		40
head, mated 1-day female		32
head, mated 4-day female		42
head, mated 20-day female		29
head, mated 1-day male		43
head, mated 4-day male		41
head, mated 20-day male		41
salivary gland, larvae L3 wandering		5
salivary gland, white prepupae		21
digestive system, larvae L3 wandering		18
digestive system, 1-day adult		59
digestive system, 4-day adult		48
digestive system, 20-day adult		40
fat body, larvae L3 wandering		8
fat body, white prepupae		9
fat body, pupae P8		11
carcass, larvae L3 wandering		10
carcass, 1-day adult		60
carcass, 4-day adult		51
carcass, 20-day adult		35
ovary, virgin 4-day female		72
ovary, mated 4-day female		54
testis, mated 4-day male		13
accessory gland, mated 4-day male		11
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		20
central nervous system, larvae L3		12
central nervous system, pupae P8		5
head, virgin 1-day female		48
head, virgin 4-day female		26
head, virgin 20-day female		40
head, mated 1-day female		32
head, mated 4-day female		42
head, mated 20-day female		29
head, mated 1-day male		43
head, mated 4-day male		41
head, mated 20-day male		41
salivary gland, larvae L3 wandering		5
salivary gland, white prepupae		21
digestive system, larvae L3 wandering		18
digestive system, 1-day adult		59
digestive system, 4-day adult		48
digestive system, 20-day adult		40
fat body, larvae L3 wandering		8
fat body, white prepupae		9
fat body, pupae P8		11
carcass, larvae L3 wandering		10
carcass, 1-day adult		60
carcass, 4-day adult		51
carcass, 20-day adult		35
ovary, virgin 4-day female		72
ovary, mated 4-day female		54
testis, mated 4-day male		13
accessory gland, mated 4-day male		11
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		20
central nervous system, larvae L3		12
central nervous system, pupae P8		5
head, virgin 1-day female		48
head, virgin 4-day female		26
head, virgin 20-day female		40
head, mated 1-day female		32
head, mated 4-day female		42
head, mated 20-day female		29
head, mated 1-day male		43
head, mated 4-day male		41
head, mated 20-day male		41
salivary gland, larvae L3 wandering		5
salivary gland, white prepupae		21
digestive system, larvae L3 wandering		18
digestive system, 1-day adult		59
digestive system, 4-day adult		48
digestive system, 20-day adult		40
fat body, larvae L3 wandering		8
fat body, white prepupae		9
fat body, pupae P8		11
carcass, larvae L3 wandering		10
carcass, 1-day adult		60
carcass, 4-day adult		51
carcass, 20-day adult		35
ovary, virgin 4-day female		72
ovary, mated 4-day female		54
testis, mated 4-day male		13
accessory gland, mated 4-day male		11
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		20
central nervous system, larvae L3		12
central nervous system, pupae P8		5
head, virgin 1-day female		(48)
head, virgin 4-day female		26
head, virgin 20-day female		(40)
head, mated 1-day female		32
head, mated 4-day female		(42)
head, mated 20-day female		29
head, mated 1-day male		(43)
head, mated 4-day male		(41)
head, mated 20-day male		(41)
salivary gland, larvae L3 wandering		5
salivary gland, white prepupae		21
digestive system, larvae L3 wandering		18
digestive system, 1-day adult		(59)
digestive system, 4-day adult		(48)
digestive system, 20-day adult		(40)
fat body, larvae L3 wandering		8
fat body, white prepupae		9
fat body, pupae P8		11
carcass, larvae L3 wandering		10
carcass, 1-day adult		(60)
carcass, 4-day adult		(51)
carcass, 20-day adult		(35)
ovary, virgin 4-day female		(72)
ovary, mated 4-day female		(54)
testis, mated 4-day male		13
accessory gland, mated 4-day male		11
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		20
central nervous system, larvae L3		12
central nervous system, pupae P8		5
head, virgin 1-day female		48
head, virgin 4-day female		26
head, virgin 20-day female		40
head, mated 1-day female		32
head, mated 4-day female		42
head, mated 20-day female		29
head, mated 1-day male		43
head, mated 4-day male		41
head, mated 20-day male		41
salivary gland, larvae L3 wandering		5
salivary gland, white prepupae		21
digestive system, larvae L3 wandering		18
digestive system, 1-day adult		59
digestive system, 4-day adult		48
digestive system, 20-day adult		40
fat body, larvae L3 wandering		8
fat body, white prepupae		9
fat body, pupae P8		11
carcass, larvae L3 wandering		10
carcass, 1-day adult		60
carcass, 4-day adult		51
carcass, 20-day adult		35
ovary, virgin 4-day female		72
ovary, mated 4-day female		54
testis, mated 4-day male		13
accessory gland, mated 4-day male		11
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		20
central nervous system, larvae L3		12
central nervous system, pupae P8		5
head, virgin 1-day female		48
head, virgin 4-day female		26
head, virgin 20-day female		40
head, mated 1-day female		32
head, mated 4-day female		42
head, mated 20-day female		29
head, mated 1-day male		43
head, mated 4-day male		41
head, mated 20-day male		41
salivary gland, larvae L3 wandering		5
salivary gland, white prepupae		21
digestive system, larvae L3 wandering		18
digestive system, 1-day adult		59
digestive system, 4-day adult		48
digestive system, 20-day adult		40
fat body, larvae L3 wandering		8
fat body, white prepupae		9
fat body, pupae P8		11
carcass, larvae L3 wandering		10
carcass, 1-day adult		60
carcass, 4-day adult		51
carcass, 20-day adult		35
ovary, virgin 4-day female		72
ovary, mated 4-day female		54
testis, mated 4-day male		13
accessory gland, mated 4-day male		11
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 18-24 hour embryonic stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		85
embryo 02-04hr		9
embryo 04-06hr		5
embryo 06-08hr		2
embryo 08-10hr		4
embryo 10-12hr		7
embryo 12-14hr		8
embryo 14-16hr		7
embryo 16-18hr		11
embryo 18-20hr		28
embryo 20-22hr		82
embryo 22-24hr		107
larva L1		90
larva L2		92
larva L3 12hr old		94
larva L3 puffstage 1-2		54
larva L3 puffstage 3-6		21
larva L3 puffstage 7-9		17
white prepupae new		21
white prepupae 12hr		16
white prepupae 24hr		11
pupae 2d postWPP		15
pupae 3d postWPP		14
pupae 4d postWPP		77
adult male 01day		69
adult male 05day		39
adult male 30day		31
adult female 01day		60
adult female 05day		67
adult female 30day		65
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(85)
embryo 02-04hr		9
embryo 04-06hr		5
embryo 06-08hr		2
embryo 08-10hr		4
embryo 10-12hr		7
embryo 12-14hr		8
embryo 14-16hr		7
embryo 16-18hr		11
embryo 18-20hr		(28)
embryo 20-22hr		(82)
embryo 22-24hr		(107)
larva L1		(90)
larva L2		(92)
larva L3 12hr old		(94)
larva L3 puffstage 1-2		(54)
larva L3 puffstage 3-6		21
larva L3 puffstage 7-9		17
white prepupae new		21
white prepupae 12hr		16
white prepupae 24hr		11
pupae 2d postWPP		15
pupae 3d postWPP		14
pupae 4d postWPP		(77)
adult male 01day		(69)
adult male 05day		(39)
adult male 30day		(31)
adult female 01day		(60)
adult female 05day		(67)
adult female 30day		(65)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		85
embryo 02-04hr		9
embryo 04-06hr		5
embryo 06-08hr		2
embryo 08-10hr		4
embryo 10-12hr		7
embryo 12-14hr		8
embryo 14-16hr		7
embryo 16-18hr		11
embryo 18-20hr		28
embryo 20-22hr		82
embryo 22-24hr		107
larva L1		90
larva L2		92
larva L3 12hr old		94
larva L3 puffstage 1-2		54
larva L3 puffstage 3-6		21
larva L3 puffstage 7-9		17
white prepupae new		21
white prepupae 12hr		16
white prepupae 24hr		11
pupae 2d postWPP		15
pupae 3d postWPP		14
pupae 4d postWPP		77
adult male 01day		69
adult male 05day		39
adult male 30day		31
adult female 01day		60
adult female 05day		67
adult female 30day		65
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		85
embryo 02-04hr		9
embryo 04-06hr		5
embryo 06-08hr		2
embryo 08-10hr		4
embryo 10-12hr		7
embryo 12-14hr		8
embryo 14-16hr		7
embryo 16-18hr		11
embryo 18-20hr		28
embryo 20-22hr		82
embryo 22-24hr		107
larva L1		90
larva L2		92
larva L3 12hr old		94
larva L3 puffstage 1-2		54
larva L3 puffstage 3-6		21
larva L3 puffstage 7-9		17
white prepupae new		21
white prepupae 12hr		16
white prepupae 24hr		11
pupae 2d postWPP		15
pupae 3d postWPP		14
pupae 4d postWPP		77
adult male 01day		69
adult male 05day		39
adult male 30day		31
adult female 01day		60
adult female 05day		67
adult female 30day		65
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		85
embryo 02-04hr		9
embryo 04-06hr		5
embryo 06-08hr		2
embryo 08-10hr		4
embryo 10-12hr		7
embryo 12-14hr		8
embryo 14-16hr		7
embryo 16-18hr		11
embryo 18-20hr		28
embryo 20-22hr		82
embryo 22-24hr		107
larva L1		90
larva L2		92
larva L3 12hr old		94
larva L3 puffstage 1-2		54
larva L3 puffstage 3-6		21
larva L3 puffstage 7-9		17
white prepupae new		21
white prepupae 12hr		16
white prepupae 24hr		11
pupae 2d postWPP		15
pupae 3d postWPP		14
pupae 4d postWPP		77
adult male 01day		69
adult male 05day		39
adult male 30day		31
adult female 01day		60
adult female 05day		67
adult female 30day		65
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(85)
embryo 02-04hr		9
embryo 04-06hr		5
embryo 06-08hr		2
embryo 08-10hr		4
embryo 10-12hr		7
embryo 12-14hr		8
embryo 14-16hr		7
embryo 16-18hr		11
embryo 18-20hr		28
embryo 20-22hr		(82)
embryo 22-24hr		(107)
larva L1		(90)
larva L2		(92)
larva L3 12hr old		(94)
larva L3 puffstage 1-2		(54)
larva L3 puffstage 3-6		21
larva L3 puffstage 7-9		17
white prepupae new		21
white prepupae 12hr		16
white prepupae 24hr		11
pupae 2d postWPP		15
pupae 3d postWPP		14
pupae 4d postWPP		(77)
adult male 01day		(69)
adult male 05day		(39)
adult male 30day		31
adult female 01day		(60)
adult female 05day		(67)
adult female 30day		(65)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		85
embryo 02-04hr		9
embryo 04-06hr		5
embryo 06-08hr		2
embryo 08-10hr		4
embryo 10-12hr		7
embryo 12-14hr		8
embryo 14-16hr		7
embryo 16-18hr		11
embryo 18-20hr		28
embryo 20-22hr		82
embryo 22-24hr		107
larva L1		90
larva L2		92
larva L3 12hr old		94
larva L3 puffstage 1-2		54
larva L3 puffstage 3-6		21
larva L3 puffstage 7-9		17
white prepupae new		21
white prepupae 12hr		16
white prepupae 24hr		11
pupae 2d postWPP		15
pupae 3d postWPP		14
pupae 4d postWPP		77
adult male 01day		69
adult male 05day		39
adult male 30day		31
adult female 01day		60
adult female 05day		67
adult female 30day		65
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		85
embryo 02-04hr		9
embryo 04-06hr		5
embryo 06-08hr		2
embryo 08-10hr		4
embryo 10-12hr		7
embryo 12-14hr		8
embryo 14-16hr		7
embryo 16-18hr		11
embryo 18-20hr		28
embryo 20-22hr		82
embryo 22-24hr		107
larva L1		90
larva L2		92
larva L3 12hr old		94
larva L3 puffstage 1-2		54
larva L3 puffstage 3-6		21
larva L3 puffstage 7-9		17
white prepupae new		21
white prepupae 12hr		16
white prepupae 24hr		11
pupae 2d postWPP		15
pupae 3d postWPP		14
pupae 4d postWPP		77
adult male 01day		69
adult male 05day		39
adult male 30day		31
adult female 01day		60
adult female 05day		67
adult female 30day		65
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		38
Schneider line 2 Sg4		16
embryonic 1182-4H		19
embryonic GM2		56
embryonic Kc167		18
embryonic S1		15
embryonic S3		35
leg disc CME L1		22
wing disc CME-W2		27
wing disc ML-DmD8		13
wing disc ML-DmD9		20
wing disc ML-DmD16-c3		13
wing disc ML-DmD21		11
wing disc ML-DmD32		3
haltere disc ML-DmD17-c3		19
eye-antennal disc ML-DmD11		23
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		8
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		19
tumorous blood cells mbn2		34
ovary fGS/OSS		13
ovary OSC		16
ovary OSS		10
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(38)
Schneider line 2 Sg4		16
embryonic 1182-4H		19
embryonic GM2		(56)
embryonic Kc167		18
embryonic S1		15
embryonic S3		(35)
leg disc CME L1		22
wing disc CME-W2		(27)
wing disc ML-DmD8		13
wing disc ML-DmD9		20
wing disc ML-DmD16-c3		13
wing disc ML-DmD21		11
wing disc ML-DmD32		3
haltere disc ML-DmD17-c3		19
eye-antennal disc ML-DmD11		23
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		8
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		19
tumorous blood cells mbn2		(34)
ovary fGS/OSS		13
ovary OSC		16
ovary OSS		10
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		38
Schneider line 2 Sg4		16
embryonic 1182-4H		19
embryonic GM2		56
embryonic Kc167		18
embryonic S1		15
embryonic S3		35
leg disc CME L1		22
wing disc CME-W2		27
wing disc ML-DmD8		13
wing disc ML-DmD9		20
wing disc ML-DmD16-c3		13
wing disc ML-DmD21		11
wing disc ML-DmD32		3
haltere disc ML-DmD17-c3		19
eye-antennal disc ML-DmD11		23
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		8
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		19
tumorous blood cells mbn2		34
ovary fGS/OSS		13
ovary OSC		16
ovary OSS		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		38
Schneider line 2 Sg4		16
embryonic 1182-4H		19
embryonic GM2		56
embryonic Kc167		18
embryonic S1		15
embryonic S3		35
leg disc CME L1		22
wing disc CME-W2		27
wing disc ML-DmD8		13
wing disc ML-DmD9		20
wing disc ML-DmD16-c3		13
wing disc ML-DmD21		11
wing disc ML-DmD32		3
haltere disc ML-DmD17-c3		19
eye-antennal disc ML-DmD11		23
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		8
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		19
tumorous blood cells mbn2		34
ovary fGS/OSS		13
ovary OSC		16
ovary OSS		10
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		38
Schneider line 2 Sg4		16
embryonic 1182-4H		19
embryonic GM2		56
embryonic Kc167		18
embryonic S1		15
embryonic S3		35
leg disc CME L1		22
wing disc CME-W2		27
wing disc ML-DmD8		13
wing disc ML-DmD9		20
wing disc ML-DmD16-c3		13
wing disc ML-DmD21		11
wing disc ML-DmD32		3
haltere disc ML-DmD17-c3		19
eye-antennal disc ML-DmD11		23
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		8
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		19
tumorous blood cells mbn2		34
ovary fGS/OSS		13
ovary OSC		16
ovary OSS		10
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(38)
Schneider line 2 Sg4		16
embryonic 1182-4H		19
embryonic GM2		(56)
embryonic Kc167		18
embryonic S1		15
embryonic S3		(35)
leg disc CME L1		22
wing disc CME-W2		27
wing disc ML-DmD8		13
wing disc ML-DmD9		20
wing disc ML-DmD16-c3		13
wing disc ML-DmD21		11
wing disc ML-DmD32		3
haltere disc ML-DmD17-c3		19
eye-antennal disc ML-DmD11		23
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		8
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		19
tumorous blood cells mbn2		(34)
ovary fGS/OSS		13
ovary OSC		16
ovary OSS		10
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		38
Schneider line 2 Sg4		16
embryonic 1182-4H		19
embryonic GM2		56
embryonic Kc167		18
embryonic S1		15
embryonic S3		35
leg disc CME L1		22
wing disc CME-W2		27
wing disc ML-DmD8		13
wing disc ML-DmD9		20
wing disc ML-DmD16-c3		13
wing disc ML-DmD21		11
wing disc ML-DmD32		3
haltere disc ML-DmD17-c3		19
eye-antennal disc ML-DmD11		23
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		8
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		19
tumorous blood cells mbn2		34
ovary fGS/OSS		13
ovary OSC		16
ovary OSS		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		38
Schneider line 2 Sg4		16
embryonic 1182-4H		19
embryonic GM2		56
embryonic Kc167		18
embryonic S1		15
embryonic S3		35
leg disc CME L1		22
wing disc CME-W2		27
wing disc ML-DmD8		13
wing disc ML-DmD9		20
wing disc ML-DmD16-c3		13
wing disc ML-DmD21		11
wing disc ML-DmD32		3
haltere disc ML-DmD17-c3		19
eye-antennal disc ML-DmD11		23
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		8
CNS ML-DmBG1-c1		13
CNS ML-DmBG2-c2		19
tumorous blood cells mbn2		34
ovary fGS/OSS		13
ovary OSC		16
ovary OSS		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		13
heat shock, 4-day adult		56
Cadmium 50 mM 6 hrs, larvae L3		66
Cadmium 50 mM 12 hrs, larvae L3		56
Cadmium 50 mM 48 hrs, 4-day adult		62
Cadmium 100 mM 48 hrs, 4-day adult		39
Copper 0.5 mM 12 hrs, larvae L3		38
Copper 15 mM 48 hrs, 4-day adult		18
Zinc 5 mM 12 hrs, larvae L3		23
Zinc 4.5 mM 48 hrs, 4-day adult		19
Ethanol 2.5% 3 hrs, larvae L3		59
Ethanol 5% 3 hrs, larvae L3		78
Ethanol 10% 3 hrs, larvae L3		84
Caffeine 1.5 mg/ml 4 hrs, larvae L3		31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		48
Caffeine 25 mg/ml 48 hrs, 4-day adult		14
Paraquat 5 mM 48 hrs, 4-day adult		52
Paraquat 10 mM 48 hrs, 4-day adult		41
Rotenone 2 μg 12 hrs, larvae L3		83
Rotenone 8 μg 12 hrs, larvae L3		78
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		13
heat shock, 4-day adult		(56)
Cadmium 50 mM 6 hrs, larvae L3		(66)
Cadmium 50 mM 12 hrs, larvae L3		(56)
Cadmium 50 mM 48 hrs, 4-day adult		(62)
Cadmium 100 mM 48 hrs, 4-day adult		(39)
Copper 0.5 mM 12 hrs, larvae L3		(38)
Copper 15 mM 48 hrs, 4-day adult		18
Zinc 5 mM 12 hrs, larvae L3		23
Zinc 4.5 mM 48 hrs, 4-day adult		19
Ethanol 2.5% 3 hrs, larvae L3		(59)
Ethanol 5% 3 hrs, larvae L3		(78)
Ethanol 10% 3 hrs, larvae L3		(84)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(31)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(48)
Caffeine 25 mg/ml 48 hrs, 4-day adult		14
Paraquat 5 mM 48 hrs, 4-day adult		(52)
Paraquat 10 mM 48 hrs, 4-day adult		(41)
Rotenone 2 μg 12 hrs, larvae L3		(83)
Rotenone 8 μg 12 hrs, larvae L3		(78)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		13
heat shock, 4-day adult		56
Cadmium 50 mM 6 hrs, larvae L3		66
Cadmium 50 mM 12 hrs, larvae L3		56
Cadmium 50 mM 48 hrs, 4-day adult		62
Cadmium 100 mM 48 hrs, 4-day adult		39
Copper 0.5 mM 12 hrs, larvae L3		38
Copper 15 mM 48 hrs, 4-day adult		18
Zinc 5 mM 12 hrs, larvae L3		23
Zinc 4.5 mM 48 hrs, 4-day adult		19
Ethanol 2.5% 3 hrs, larvae L3		59
Ethanol 5% 3 hrs, larvae L3		78
Ethanol 10% 3 hrs, larvae L3		84
Caffeine 1.5 mg/ml 4 hrs, larvae L3		31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		48
Caffeine 25 mg/ml 48 hrs, 4-day adult		14
Paraquat 5 mM 48 hrs, 4-day adult		52
Paraquat 10 mM 48 hrs, 4-day adult		41
Rotenone 2 μg 12 hrs, larvae L3		83
Rotenone 8 μg 12 hrs, larvae L3		78
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		13
heat shock, 4-day adult		56
Cadmium 50 mM 6 hrs, larvae L3		66
Cadmium 50 mM 12 hrs, larvae L3		56
Cadmium 50 mM 48 hrs, 4-day adult		62
Cadmium 100 mM 48 hrs, 4-day adult		39
Copper 0.5 mM 12 hrs, larvae L3		38
Copper 15 mM 48 hrs, 4-day adult		18
Zinc 5 mM 12 hrs, larvae L3		23
Zinc 4.5 mM 48 hrs, 4-day adult		19
Ethanol 2.5% 3 hrs, larvae L3		59
Ethanol 5% 3 hrs, larvae L3		78
Ethanol 10% 3 hrs, larvae L3		84
Caffeine 1.5 mg/ml 4 hrs, larvae L3		31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		48
Caffeine 25 mg/ml 48 hrs, 4-day adult		14
Paraquat 5 mM 48 hrs, 4-day adult		52
Paraquat 10 mM 48 hrs, 4-day adult		41
Rotenone 2 μg 12 hrs, larvae L3		83
Rotenone 8 μg 12 hrs, larvae L3		78
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		13
heat shock, 4-day adult		56
Cadmium 50 mM 6 hrs, larvae L3		66
Cadmium 50 mM 12 hrs, larvae L3		56
Cadmium 50 mM 48 hrs, 4-day adult		62
Cadmium 100 mM 48 hrs, 4-day adult		39
Copper 0.5 mM 12 hrs, larvae L3		38
Copper 15 mM 48 hrs, 4-day adult		18
Zinc 5 mM 12 hrs, larvae L3		23
Zinc 4.5 mM 48 hrs, 4-day adult		19
Ethanol 2.5% 3 hrs, larvae L3		59
Ethanol 5% 3 hrs, larvae L3		78
Ethanol 10% 3 hrs, larvae L3		84
Caffeine 1.5 mg/ml 4 hrs, larvae L3		31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		48
Caffeine 25 mg/ml 48 hrs, 4-day adult		14
Paraquat 5 mM 48 hrs, 4-day adult		52
Paraquat 10 mM 48 hrs, 4-day adult		41
Rotenone 2 μg 12 hrs, larvae L3		83
Rotenone 8 μg 12 hrs, larvae L3		78
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		13
heat shock, 4-day adult		(56)
Cadmium 50 mM 6 hrs, larvae L3		(66)
Cadmium 50 mM 12 hrs, larvae L3		(56)
Cadmium 50 mM 48 hrs, 4-day adult		(62)
Cadmium 100 mM 48 hrs, 4-day adult		(39)
Copper 0.5 mM 12 hrs, larvae L3		(38)
Copper 15 mM 48 hrs, 4-day adult		18
Zinc 5 mM 12 hrs, larvae L3		23
Zinc 4.5 mM 48 hrs, 4-day adult		19
Ethanol 2.5% 3 hrs, larvae L3		(59)
Ethanol 5% 3 hrs, larvae L3		(78)
Ethanol 10% 3 hrs, larvae L3		(84)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(48)
Caffeine 25 mg/ml 48 hrs, 4-day adult		14
Paraquat 5 mM 48 hrs, 4-day adult		(52)
Paraquat 10 mM 48 hrs, 4-day adult		(41)
Rotenone 2 μg 12 hrs, larvae L3		(83)
Rotenone 8 μg 12 hrs, larvae L3		(78)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		13
heat shock, 4-day adult		56
Cadmium 50 mM 6 hrs, larvae L3		66
Cadmium 50 mM 12 hrs, larvae L3		56
Cadmium 50 mM 48 hrs, 4-day adult		62
Cadmium 100 mM 48 hrs, 4-day adult		39
Copper 0.5 mM 12 hrs, larvae L3		38
Copper 15 mM 48 hrs, 4-day adult		18
Zinc 5 mM 12 hrs, larvae L3		23
Zinc 4.5 mM 48 hrs, 4-day adult		19
Ethanol 2.5% 3 hrs, larvae L3		59
Ethanol 5% 3 hrs, larvae L3		78
Ethanol 10% 3 hrs, larvae L3		84
Caffeine 1.5 mg/ml 4 hrs, larvae L3		31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		48
Caffeine 25 mg/ml 48 hrs, 4-day adult		14
Paraquat 5 mM 48 hrs, 4-day adult		52
Paraquat 10 mM 48 hrs, 4-day adult		41
Rotenone 2 μg 12 hrs, larvae L3		83
Rotenone 8 μg 12 hrs, larvae L3		78
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		13
heat shock, 4-day adult		56
Cadmium 50 mM 6 hrs, larvae L3		66
Cadmium 50 mM 12 hrs, larvae L3		56
Cadmium 50 mM 48 hrs, 4-day adult		62
Cadmium 100 mM 48 hrs, 4-day adult		39
Copper 0.5 mM 12 hrs, larvae L3		38
Copper 15 mM 48 hrs, 4-day adult		18
Zinc 5 mM 12 hrs, larvae L3		23
Zinc 4.5 mM 48 hrs, 4-day adult		19
Ethanol 2.5% 3 hrs, larvae L3		59
Ethanol 5% 3 hrs, larvae L3		78
Ethanol 10% 3 hrs, larvae L3		84
Caffeine 1.5 mg/ml 4 hrs, larvae L3		31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		48
Caffeine 25 mg/ml 48 hrs, 4-day adult		14
Paraquat 5 mM 48 hrs, 4-day adult		52
Paraquat 10 mM 48 hrs, 4-day adult		41
Rotenone 2 μg 12 hrs, larvae L3		83
Rotenone 8 μg 12 hrs, larvae L3		78
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

BDGP expression data

•

FI02890

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0037890

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG17734-RA;CG17734-RB

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable

CG17734^EY06693

viable, with Scer\GAL4^pnr-MD237

Sterility

Allele

fertile

CG17734^EY06693

Other Phenotypes

Allele

chemical resistant

CG17734^KG06609

hyperactive | conditional

CG17734^KG06609

Phenotype manifest in

Allele

Classical Alleles ( 9 )

For All Classical Alleles Show

Allele of CG17734	Mutagen	Stocks	Known lesion
CG17734^5-HA-3014		1	--
CG17734^5-SZ-3906		1	--
CG17734^c06431		1	--
CG17734^d05338		1	--
CG17734^EY06693	P-element activity	1	--
CG17734^f01538	piggyBac transposase	1	--
CG17734^KG06609		1	--
CG17734^CB-5756-3		0	--
CG17734^DG17603		0	--

Alleles Carried on Transgenic Constructs ( 3 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG17734	Mutagen	Stocks	Known lesion
CG17734^GD17176	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG17734^GD4637	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG17734^KK112172	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes

Aneuploid Aberrations

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD4637}

P{GD17176}

P{KK112172}

Insertions

Type of insertions

Name

Expression data

insertion of mobile activating element

P{EPgy2}CG17734^EY06693

P{XP}CG17734^d05338

miscellaneous insertions

P{RS3}CG17734^CB-5756-3

P{RS5}CG17734^5-HA-3014

P{RS5}CG17734^5-SZ-3906

P{SUPor-P}CG17734^KG06609

P{wHy}CG17734^DG17603

PBac{PB}CG17734^c06431

PBac{WH}CG17734^f01538

Gene Ontology: Function, Process & Cellular Component ( 1 unique term )

Terms Based on Experimental Evidence ( 1 term )

Molecular Function ( 0 terms)

Biological Process

CV term

Evidence

References

behavioral response to ethanol

inferred from mutant phenotype

(Kong et al., 2010)

Cellular Component ( 0 terms)

Terms Based on Predictions or Assertions ( 0 terms )

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

protein-protein

Interacting group

Assay

References

CG17734 - CG2789

anti tag coimmunoprecipitation, peptide massfingerprinting

(Mintseris et al., 2009.11.23)

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG17734 allele

Gene

References

External Data

Linkouts

BioGRID - A database of protein and genetic interactions

•

66492

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0037890

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

41359

Orthologs

OrthoDB Orthologs (41) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

No orthologs identified

Dipteran inclusive ortholog search

No orthologs identified

Insect inclusive ortholog search

EOG62BW6P

Arthropod inclusive ortholog search

EOG6P8D24

Metazoa inclusive ortholog search

EOG65J4T2

Orthologs in Drosophila Species (None identified)

No orthologies identified

Orthologs in non-Drosophila Dipterans (None identified)

No non-Drosophilid orthologies identified

Orthologs in non-Dipteran Insects (EOG62BW6P)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\GB53947

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG010565

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH17439

Atta cephalotes

Leafcutter ant

Acep\ACEP22133

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL16141

Linepithema humile

Argentine ant

Lhum\LH12421

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB17072

Solenopsis invicta

Red fire ant

Sinv\SINV24202

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI30903

Bombyx mori

Silkmoth

Bmor\BGIBMGA003358

Bombyx mori

Silkmoth

Bmor\BGIBMGA003356

Pediculus humanus

Human body louse

Phum\PHUM222090

Tribolium castaneum

Red flour beetle

Tcas\TC003997

Orthologs in non-Insect Arthropods (EOG6P8D24)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Daphnia pulex

Water flea

Dpux\dsrA

Ixodes scapularis

Deer tick

Isca\ISCW010981

Orthologs in non-Arthropod Metazoa (EOG65J4T2)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Caenorhabditis elegans

Nematode

Cele\M05D6.5

Caenorhabditis elegans

Nematode

Cele\T20D3.6

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_008042gn

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_005268gn

Danio rerio

Zebrafish

Drer\higd2a

Danio rerio

Zebrafish

Drer\hig1

Xenopus tropicalis

Western clawed frog

Xtro\higd1a

Xenopus tropicalis

Western clawed frog

Xtro\higd2a

Xenopus tropicalis

Western clawed frog

Xtro\higd1b

Xenopus tropicalis

Western clawed frog

Xtro\higd1c

Gallus gallus

Domestic chicken

Ggal\HIGD1A

Gallus gallus

Domestic chicken

Ggal\HIGD2A

Mus musculus

House mouse

Mmus\Higd1c

Mus musculus

House mouse

Mmus\Higd2a

Mus musculus

House mouse

Mmus\Higd1b

Mus musculus

House mouse

Mmus\Higd1a

Rattus norvegicus

Norway rat

Rnor\Higd1a

Rattus norvegicus

Norway rat

Rnor\ENSRNOG00000003008

Rattus norvegicus

Norway rat

Rnor\Higd2al1

Rattus norvegicus

Norway rat

Rnor\Higd2a

Rattus norvegicus

Norway rat

Rnor\Higd1b

Homo sapiens

Human

Hsap\HIGD2A

Homo sapiens

Human

Hsap\HIGD1B

Homo sapiens

Human

Hsap\HIGD1A

Homo sapiens

Human

Hsap\HIGD1C

Homo sapiens

Human

Hsap\HIGD2B

Human Orthologs (5)

Gene

OMIM

HGNC

AAA Orthologs (11) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA14631

Drosophila persimilis

Dper\GL12612

Drosophila willistoni

Dwil\GK13290

Drosophila virilis

Dvir\GJ23799

Drosophila mojavensis

Dmoj\GI10064

Drosophila grimshawi

Dgri\GH18805

Stocks & Reagents

Stocks Listed in FlyBase ( 10 )

Bloomington

19856

y¹ w^67c23; P{EPgy2}CG17734^EY06693

14306

y¹ w^67c23; P{SUPor-P}CG17734^KG06609 ry⁵⁰⁶

Harvard

P{XP}CG17734^d05338

PBac{PB}CG17734^c06431

PBac{WH}CG17734^f01538

Kyoto

125771

w¹¹¹⁸; P{RS5}CG17734^5-HA-3014

126209

w¹¹¹⁸; P{RS5}CG17734^5-SZ-3906

VDRC

v102605

P{KK112172}VIE-260B

v13791

w¹¹¹⁸; P{GD4637}v13791

v49497

w¹¹¹⁸; P{GD17176}v49497

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 45 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0037890

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

41359

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Source for merge of: CG17734 BcDNA:RH54117

(FlyBase, 1996-)

Additional comments

The CG11825 gene may be derived from the CG17734 gene by retroposition.

(Betran et al., 2002)

Source for merge of CG17734 BcDNA:RH54117 was a shared cDNA (date:030728).

(FlyBase, 1996-)

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

RefSeq (Proteins)

•

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

41359

UniProtKB/TrEMBL

•

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Hypoxia induced protein, domain (IPR007667)

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

•

FI02890

Linkouts

BioGRID - A database of protein and genetic interactions

•

66492

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0037890

DRSC - Results from RNAi screens.

•

FBgn0037890

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0037890

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG17734-RA;CG17734-RB

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0037890

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

41359

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

41359

modMine - Data generated by the modENCODE project.

•

FBgn0037890

Synonyms & Secondary IDs ( 2 )

Reported As

Symbol Synonym

BcDNA:RH54117

CG17734

(Langille and Clark, 2007, Akdemir et al., 2007, Toledano-Katchalski et al., 2007, Li et al., 2009, Roxstrom-Lindquist et al., 2004, Keleman et al., 2009.8.5, Fernández-Ayala et al., 2010, Kong et al., 2010, Cammarato et al., 2011, Coolon et al., 2012)

Name Synonym

Secondary FlyBase IDs

FBgn0063654

References ( 26 )

Generate a list of

All references relating to this gene ( 26 )

List References by type

Recent research papers ( 2 )

Coolon et al., 2012, Cell Rep. 2(1): 69--75: Genomic Imprinting Absent in Drosophila melanogaster Adult Females. [FBrf0219040]
Díaz-Castillo and Ranz, 2012, Mol. Biol. Evol. 29(9): 2105--2108: Nuclear chromosome dynamics in the Drosophila male germ line contribute to the nonrandom genomic distribution of retrogenes. [FBrf0219274]

Show all research papers ...