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Gene Dmel\Scgβ

General Information
Symbol	Dmel\Scgβ	Species	D. melanogaster
Name	Sarcoglycan β	Annotation symbol	CG5657
Feature type	protein_coding_gene	FlyBase ID	FBgn0038042
Gene Model Status	Current	Stock availability	2 publicly available
Also Known As	dscgβ
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	87B9-87B9	Sequence location	3R:8,246,958..8,248,151 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Sarcoglycan β is referred to in FlyBase by the symbol Dmel\Scgβ (CG5657, FBgn0038042). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of muscle. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: cytoskeleton organization. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Sarcoglycan complex subunit protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system. Comments on Affy2 ProbeSet: ProbeSet 1634402_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Scgbeta. Gene sequence location is 3R:8246958..8248151.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features HFA15854 BKN27860
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 87B9-87B9   Limits computationally determined from genome sequence between P{PZ}svp07842 and P{lacW}Vha55j2E9
Experimentally Determined Cytological Location
Cytogenetic map Notes References 87B14-87B15     (Greener, 2000.6.14)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Scgβ for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Scgβ-RA FBtr0082596  NM_079603   1194   352
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Scgβ-PA   FBpp0082068   38.1   352   4.86     NP_524327   AAF54808
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Sarcoglycan complex subunit protein (IPR006875)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA141502   AA141503   AE014297 AAF54808   AF277392 AAG17401   AY071368 AAL48990   BI242654
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9GT65 Q9VG77
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0038042    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0038042 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0038042 expression level Developmental Stage   Expression Level embryo 00-02hr    18 embryo 02-04hr    107 embryo 04-06hr    105 embryo 06-08hr    110 embryo 08-10hr    115 embryo 10-12hr    774 embryo 12-14hr    814 embryo 14-16hr    1792 embryo 16-18hr    1560 embryo 18-20hr    1680 embryo 20-22hr    1300 embryo 22-24hr    1214 larva L1    1601 larva L2    631 larva L3 12hr old    216 larva L3 puffstage 1-2    232 larva L3 puffstage 3-6    333 larva L3 puffstage 7-9    404 white prepupae new    471 white prepupae 12hr    1039 white prepupae 24hr    1256 pupae 2d postWPP    1506 pupae 3d postWPP    1212 pupae 4d postWPP    687 adult male 01day    621 adult male 05day    734 adult male 30day    1054 adult female 01day    388 adult female 05day    116 adult female 30day    137 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    18 embryo 02-04hr  107 embryo 04-06hr  105 embryo 06-08hr  (110) embryo 08-10hr  (115) embryo 10-12hr  (774) embryo 12-14hr  (814) embryo 14-16hr  (1792) embryo 16-18hr  (1560) embryo 18-20hr  (1680) embryo 20-22hr  (1300) embryo 22-24hr  (1214) larva L1  (1601) larva L2  (631) larva L3 12hr old  (216) larva L3 puffstage 1-2  (232) larva L3 puffstage 3-6  (333) larva L3 puffstage 7-9  (404) white prepupae new  (471) white prepupae 12hr  (1039) white prepupae 24hr  (1256) pupae 2d postWPP  (1506) pupae 3d postWPP  (1212) pupae 4d postWPP  (687) adult male 01day  (621) adult male 05day  (734) adult male 30day  (1054) adult female 01day  (388) adult female 05day  (116) adult female 30day  (137) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    18 embryo 02-04hr    107 embryo 04-06hr    105 embryo 06-08hr    110 embryo 08-10hr    115 embryo 10-12hr    774 embryo 12-14hr    814 embryo 14-16hr  (1792) embryo 16-18hr  (1560) embryo 18-20hr  (1680) embryo 20-22hr    1300 embryo 22-24hr    1214 larva L1  (1601) larva L2    631 larva L3 12hr old    216 larva L3 puffstage 1-2    232 larva L3 puffstage 3-6    333 larva L3 puffstage 7-9    404 white prepupae new    471 white prepupae 12hr    1039 white prepupae 24hr    1256 pupae 2d postWPP  1506 pupae 3d postWPP    1212 pupae 4d postWPP    687 adult male 01day    621 adult male 05day    734 adult male 30day    1054 adult female 01day    388 adult female 05day    116 adult female 30day    137 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    18 embryo 02-04hr    107 embryo 04-06hr    105 embryo 06-08hr    110 embryo 08-10hr    115 embryo 10-12hr    774 embryo 12-14hr    814 embryo 14-16hr    1792 embryo 16-18hr    1560 embryo 18-20hr    1680 embryo 20-22hr    1300 embryo 22-24hr    1214 larva L1    1601 larva L2    631 larva L3 12hr old    216 larva L3 puffstage 1-2    232 larva L3 puffstage 3-6    333 larva L3 puffstage 7-9    404 white prepupae new    471 white prepupae 12hr    1039 white prepupae 24hr    1256 pupae 2d postWPP    1506 pupae 3d postWPP    1212 pupae 4d postWPP    687 adult male 01day    621 adult male 05day    734 adult male 30day    1054 adult female 01day    388 adult female 05day    116 adult female 30day    137 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    18 embryo 02-04hr    107 embryo 04-06hr    105 embryo 06-08hr    110 embryo 08-10hr    115 embryo 10-12hr    774 embryo 12-14hr    814 embryo 14-16hr    1792 embryo 16-18hr    1560 embryo 18-20hr    1680 embryo 20-22hr    1300 embryo 22-24hr    1214 larva L1    1601 larva L2    631 larva L3 12hr old    216 larva L3 puffstage 1-2    232 larva L3 puffstage 3-6    333 larva L3 puffstage 7-9    404 white prepupae new    471 white prepupae 12hr    1039 white prepupae 24hr    1256 pupae 2d postWPP    1506 pupae 3d postWPP    1212 pupae 4d postWPP    687 adult male 01day    621 adult male 05day    734 adult male 30day    1054 adult female 01day    388 adult female 05day    116 adult female 30day    137 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0038042 expression level Developmental Stage   Expression Level embryo 00-02hr    18 embryo 02-04hr    107 embryo 04-06hr    105 embryo 06-08hr    110 embryo 08-10hr    115 embryo 10-12hr    774 embryo 12-14hr    814 embryo 14-16hr    1792 embryo 16-18hr    1560 embryo 18-20hr    1680 embryo 20-22hr    1300 embryo 22-24hr    1214 larva L1    1601 larva L2    631 larva L3 12hr old    216 larva L3 puffstage 1-2    232 larva L3 puffstage 3-6    333 larva L3 puffstage 7-9    404 white prepupae new    471 white prepupae 12hr    1039 white prepupae 24hr    1256 pupae 2d postWPP    1506 pupae 3d postWPP    1212 pupae 4d postWPP    687 adult male 01day    621 adult male 05day    734 adult male 30day    1054 adult female 01day    388 adult female 05day    116 adult female 30day    137 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    18 embryo 02-04hr  107 embryo 04-06hr  105 embryo 06-08hr  110 embryo 08-10hr  115 embryo 10-12hr  (774) embryo 12-14hr  (814) embryo 14-16hr  (1792) embryo 16-18hr  (1560) embryo 18-20hr  (1680) embryo 20-22hr  (1300) embryo 22-24hr  (1214) larva L1  (1601) larva L2  (631) larva L3 12hr old  (216) larva L3 puffstage 1-2  (232) larva L3 puffstage 3-6  (333) larva L3 puffstage 7-9  (404) white prepupae new  (471) white prepupae 12hr  (1039) white prepupae 24hr  (1256) pupae 2d postWPP  (1506) pupae 3d postWPP  (1212) pupae 4d postWPP  (687) adult male 01day  (621) adult male 05day  (734) adult male 30day  (1054) adult female 01day  (388) adult female 05day  116 adult female 30day  137 Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    18 embryo 02-04hr    107 embryo 04-06hr    105 embryo 06-08hr    110 embryo 08-10hr    115 embryo 10-12hr    774 embryo 12-14hr    814 embryo 14-16hr  1792 embryo 16-18hr  1560 embryo 18-20hr  1680 embryo 20-22hr    1300 embryo 22-24hr    1214 larva L1  1601 larva L2    631 larva L3 12hr old    216 larva L3 puffstage 1-2    232 larva L3 puffstage 3-6    333 larva L3 puffstage 7-9    404 white prepupae new    471 white prepupae 12hr    1039 white prepupae 24hr    1256 pupae 2d postWPP  1506 pupae 3d postWPP    1212 pupae 4d postWPP    687 adult male 01day    621 adult male 05day    734 adult male 30day    1054 adult female 01day    388 adult female 05day    116 adult female 30day    137 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    18 embryo 02-04hr    107 embryo 04-06hr    105 embryo 06-08hr    110 embryo 08-10hr    115 embryo 10-12hr    774 embryo 12-14hr    814 embryo 14-16hr    1792 embryo 16-18hr    1560 embryo 18-20hr    1680 embryo 20-22hr    1300 embryo 22-24hr    1214 larva L1    1601 larva L2    631 larva L3 12hr old    216 larva L3 puffstage 1-2    232 larva L3 puffstage 3-6    333 larva L3 puffstage 7-9    404 white prepupae new    471 white prepupae 12hr    1039 white prepupae 24hr    1256 pupae 2d postWPP    1506 pupae 3d postWPP    1212 pupae 4d postWPP    687 adult male 01day    621 adult male 05day    734 adult male 30day    1054 adult female 01day    388 adult female 05day    116 adult female 30day    137 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    18 embryo 02-04hr    107 embryo 04-06hr    105 embryo 06-08hr    110 embryo 08-10hr    115 embryo 10-12hr    774 embryo 12-14hr    814 embryo 14-16hr    1792 embryo 16-18hr    1560 embryo 18-20hr    1680 embryo 20-22hr    1300 embryo 22-24hr    1214 larva L1    1601 larva L2    631 larva L3 12hr old    216 larva L3 puffstage 1-2    232 larva L3 puffstage 3-6    333 larva L3 puffstage 7-9    404 white prepupae new    471 white prepupae 12hr    1039 white prepupae 24hr    1256 pupae 2d postWPP    1506 pupae 3d postWPP    1212 pupae 4d postWPP    687 adult male 01day    621 adult male 05day    734 adult male 30day    1054 adult female 01day    388 adult female 05day    116 adult female 30day    137 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0038042    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0038042 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0038042 expression level Tissue   Expression Level Larval Central Nervous System    235.65 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    9.8 Larval Fat Body    4.3 Larval Salivary Gland    5.8 Larval Trachea no informative data Larval Carcass no informative data Adult Head    156.8 Adult Eye    377.125 Adult Brain    441.4 Adult Thoracic-Abdominal Ganglion    296.2 Adult Crop    40.8 Adult Midgut no informative data Adult Hindgut    20.6 Adult Malpighian Tubules no informative data Adult Fat Body    8.4 Adult Salivary Gland    7.4 Adult Heart    44.225 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    3.2 Adult Testis    18 Adult Male Accessory Gland    53.9 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    235.65 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    9.8 Larval Fat Body    4.3 Larval Salivary Gland    5.8 Larval Trachea no informative data Larval Carcass no informative data Adult Head    156.8 Adult Eye    377.125 Adult Brain    441.4 Adult Thoracic-Abdominal Ganglion    296.2 Adult Crop    40.8 Adult Midgut no informative data Adult Hindgut    20.6 Adult Malpighian Tubules no informative data Adult Fat Body    8.4 Adult Salivary Gland    7.4 Adult Heart    44.225 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    3.2 Adult Testis    18 Adult Male Accessory Gland    53.9 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    235.65 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    9.8 Larval Fat Body    4.3 Larval Salivary Gland    5.8 Larval Trachea no informative data Larval Carcass no informative data Adult Head    156.8 Adult Eye    377.125 Adult Brain    441.4 Adult Thoracic-Abdominal Ganglion    296.2 Adult Crop    40.8 Adult Midgut no informative data Adult Hindgut    20.6 Adult Malpighian Tubules no informative data Adult Fat Body    8.4 Adult Salivary Gland    7.4 Adult Heart    44.225 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    3.2 Adult Testis    18 Adult Male Accessory Gland    53.9 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    235.65 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    9.8 Larval Fat Body    4.3 Larval Salivary Gland    5.8 Larval Trachea no informative data Larval Carcass no informative data Adult Head    156.8 Adult Eye    377.125 Adult Brain    441.4 Adult Thoracic-Abdominal Ganglion    296.2 Adult Crop    40.8 Adult Midgut no informative data Adult Hindgut    20.6 Adult Malpighian Tubules no informative data Adult Fat Body    8.4 Adult Salivary Gland    7.4 Adult Heart    44.225 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    3.2 Adult Testis    18 Adult Male Accessory Gland    53.9 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0038042 expression level Tissue   Expression Level Larval Central Nervous System    235.65 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    9.8 Larval Fat Body    4.3 Larval Salivary Gland    5.8 Larval Trachea no informative data Larval Carcass no informative data Adult Head    156.8 Adult Eye    377.125 Adult Brain    441.4 Adult Thoracic-Abdominal Ganglion    296.2 Adult Crop    40.8 Adult Midgut no informative data Adult Hindgut    20.6 Adult Malpighian Tubules no informative data Adult Fat Body    8.4 Adult Salivary Gland    7.4 Adult Heart    44.225 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    3.2 Adult Testis    18 Adult Male Accessory Gland    53.9 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    235.65 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    9.8 Larval Fat Body    4.3 Larval Salivary Gland    5.8 Larval Trachea no informative data Larval Carcass no informative data Adult Head    156.8 Adult Eye    377.125 Adult Brain    441.4 Adult Thoracic-Abdominal Ganglion    296.2 Adult Crop    40.8 Adult Midgut no informative data Adult Hindgut    20.6 Adult Malpighian Tubules no informative data Adult Fat Body    8.4 Adult Salivary Gland    7.4 Adult Heart    44.225 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    3.2 Adult Testis    18 Adult Male Accessory Gland    53.9 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    235.65 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    9.8 Larval Fat Body    4.3 Larval Salivary Gland    5.8 Larval Trachea no informative data Larval Carcass no informative data Adult Head    156.8 Adult Eye    377.125 Adult Brain    441.4 Adult Thoracic-Abdominal Ganglion    296.2 Adult Crop    40.8 Adult Midgut no informative data Adult Hindgut    20.6 Adult Malpighian Tubules no informative data Adult Fat Body    8.4 Adult Salivary Gland    7.4 Adult Heart    44.225 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    3.2 Adult Testis    18 Adult Male Accessory Gland    53.9 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    235.65 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    9.8 Larval Fat Body    4.3 Larval Salivary Gland    5.8 Larval Trachea no informative data Larval Carcass no informative data Adult Head    156.8 Adult Eye    377.125 Adult Brain    441.4 Adult Thoracic-Abdominal Ganglion    296.2 Adult Crop    40.8 Adult Midgut no informative data Adult Hindgut    20.6 Adult Malpighian Tubules no informative data Adult Fat Body    8.4 Adult Salivary Gland    7.4 Adult Heart    44.225 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    3.2 Adult Testis    18 Adult Male Accessory Gland    53.9 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea no informative data Larval Carcass no informative data Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut no informative data Adult Hindgut     Adult Malpighian Tubules no informative data Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    156.8   NA  Eye    377.125   NA  Brain    441.4   235.65  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    296.2   NA  Crop    40.8   no informative data  Midgut    no informative data   no informative data  Hindgut    20.6   9.8  Malpighian Tubules    no informative data   4.3  Fat Body    8.4   5.8  Salivary Gland    7.4   NA  Heart    44.225   no informative data  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    3.2   NA  Testis    18   NA  Male Accessory Gland    53.9   no informative data  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_29
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038042 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5657-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Scgβ Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of Scgβ Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Scgβ Class Mutagen Stocks Known lesion ScgβGD2948 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes ScgβJF03228 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6164 (Ryder, 2004.4.26) Df(3R)Exel6165 (Ryder, 2004.4.26) Df(3R)Exel7316 (Ryder, 2004.4.26) Df(3R)pps1 (Johnson et al., 2010)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
structural constituent of muscle inferred from sequence or structural similarity with human SGCB (Greener and Roberts, 2000)
Biological Process
CV term Evidence References
cytoskeleton organization inferred from electronic annotation with InterPro:IPR006875 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR006875 (FlyBase Curators et al., 2004-) sarcoglycan complex inferred from sequence or structural similarity with human SGCB (Greener and Roberts, 2000) non-traceable author statement (Greener, 2000.6.14)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Scgβ allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0038042 DroID - A comprehensive database of gene and protein interactions. • FBgn0038042 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41525
Orthologs
Genome-wide drosophilid orthologs	Dana\GF17045 Dere\GG17128 Dgri\GH17465 Dmoj\GI22789 Dper\GL27177 Dpse\GA19038 Dsec\GM26011 Dsim\GD20569 Dvir\GJ22792 Dwil\GK12845 Dyak\GE24519
Curated drosophilid orthologs	Dpse\GA19038
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL006051-PA Aedes aegypti (mosquito) AGAP001996-PA Anopheles gambiae (mosquito) XP_624841.1 Apis mellifera (honey bee) XP_001948725.1 Acyrthosiphon pisum (pea aphid) 276577 Branchiostoma floridae (lancelet) ENSBTAP00000019435 Bos taurus (bovine) CBP36426 Caenorhabditis briggsae (nematode) CE35984 Caenorhabditis elegans (worm) ENSCAFP00000002941 Canis familiaris (dog) CPIJ006944 Culex pipens (mosquito) ENSCPOP00000012553 Cavia porcellus (guinea pig) ENSDARP00000068661 Danio rerio (zebra fish) ENSECAP00000017694 Equus caballus (horse) ENSGACP00000018752 Gymnopilus aculeatus (mushroom) ENSGALP00000031451 Gallus gallus (chicken) ENSP00000370839 Homo sapiens (human) ISCW008925-PA Ixodes scapularis (deer tick) 234314 Lottia gigantea (owl limpet) ENSMODP00000025826 Monodelphis domestica (gray opossum) ENSMMUP00000024924 Macaca mulatta (rhesus monkey) ENSMUSP00000084421 Mus musculus (house mouse) 242600 Nematostella vectensis (starlet anemone) XP_001607447.1 Nasonia vitripennis (wasp) ENSOANP00000000979 Ornithorynchus anatinus (platypus) ENSORLP00000000208 Oryzias latipes (japanese killifish) PHUM004837-PA Pediculus humanus (human body louse) ENSPPYP00000016507 Pongo pygmaeus (orangutan) ENSPTRP00000027615 Pan troglodytes (chimpanzee) ENSRNOP00000002921 Rattus norvegicus (norway rat) XP_001187555.1 Strongylocentrotus purpuratus (purple sea urchin) XP_968260.1 Tribolium castaneum (red flour beetle) ENSTNIP00000020814 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000038019 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000025535 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV10829 LH16660 ISCW008925 FBgn0241633 FBgn0214854 FBgn0209896 FBgn0192037 FBgn0180867 FBgn0079036 FBgn0164758 FBgn0145516 FBgn0124935 FBgn0109356 FBgn0094064 CPIJ006944 BGIBMGA014329 BGIBMGA009552 ACYPI40503 ACYPI006994 GB30485 GB19716 AGAP001996 AAEL006051 PB22546 PHUM361350 GLEAN_04520
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
Bloomington	29551 y1 v1; P{TRiP.JF03228}attP2/TM3, Sb1
VDRC	v51526 w1118 P{GD2948}v51526
Genomic Clones ( 1 )
	BACR28I14 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 3 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE40051
Other clones	DPiM_RE40051
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	CK01871
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0038042 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41525
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Scgβ CG5657 (FlyBase, 1996-)
Source for database merge of
Additional comments	FlyBase curator comment: the insertion in the "f01979" Exelixis line (PBac{WH}CG17202f01979) was originally assigned to the Scgβ gene in FBrf0179797, resulting in the "Scgβf01979" (FBal0159778) allele. However, FBrf0184340 shows that the insertion is actually within CG17202. (Bloomington Drosophila Stock Center, 2004.11.6) Source for identity of Scgβ CG5657 was sequence comparison (date:001003). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079603 RefSeq (Proteins) • NP_524327 DDBJ / EMBL / GenBank • AAF54808 AAG17401 AAL48990 AF277392 AY071368 BI242654 Entrez Gene - A searchable database of RefSeq genes. • 41525 UniProtKB/TrEMBL • Q9GT65 Q9VG77
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Sarcoglycan complex subunit protein (IPR006875)
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0038042 DroID - A comprehensive database of gene and protein interactions. • FBgn0038042 DRSC - Results from RNAi screens. • FBgn0038042 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038042 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5657-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0038042 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41525 InParanoid A subset of ortholog calls from InParanoid. • AAEL006051-PA Aedes aegypti (mosquito) AGAP001996-PA Anopheles gambiae (mosquito) XP_624841.1 Apis mellifera (honey bee) XP_001948725.1 Acyrthosiphon pisum (pea aphid) 276577 Branchiostoma floridae (lancelet) ENSBTAP00000019435 Bos taurus (bovine) CBP36426 Caenorhabditis briggsae (nematode) CE35984 Caenorhabditis elegans (worm) ENSCAFP00000002941 Canis familiaris (dog) CPIJ006944 Culex pipens (mosquito) ENSCPOP00000012553 Cavia porcellus (guinea pig) ENSDARP00000068661 Danio rerio (zebra fish) ENSECAP00000017694 Equus caballus (horse) ENSGACP00000018752 Gymnopilus aculeatus (mushroom) ENSGALP00000031451 Gallus gallus (chicken) ENSP00000370839 Homo sapiens (human) ISCW008925-PA Ixodes scapularis (deer tick) 234314 Lottia gigantea (owl limpet) ENSMODP00000025826 Monodelphis domestica (gray opossum) ENSMMUP00000024924 Macaca mulatta (rhesus monkey) ENSMUSP00000084421 Mus musculus (house mouse) 242600 Nematostella vectensis (starlet anemone) XP_001607447.1 Nasonia vitripennis (wasp) ENSOANP00000000979 Ornithorynchus anatinus (platypus) ENSORLP00000000208 Oryzias latipes (japanese killifish) PHUM004837-PA Pediculus humanus (human body louse) ENSPPYP00000016507 Pongo pygmaeus (orangutan) ENSPTRP00000027615 Pan troglodytes (chimpanzee) ENSRNOP00000002921 Rattus norvegicus (norway rat) XP_001187555.1 Strongylocentrotus purpuratus (purple sea urchin) XP_968260.1 Tribolium castaneum (red flour beetle) ENSTNIP00000020814 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000038019 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000025535 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41525 modMine - Data generated by the modENCODE project. • FBgn0038042 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV10829 LH16660 ISCW008925 FBgn0241633 FBgn0214854 FBgn0209896 FBgn0192037 FBgn0180867 FBgn0079036 FBgn0164758 FBgn0145516 FBgn0124935 FBgn0109356 FBgn0094064 CPIJ006944 BGIBMGA014329 BGIBMGA009552 ACYPI40503 ACYPI006994 GB30485 GB19716 AGAP001996 AAEL006051 PB22546 PHUM361350 GLEAN_04520
Synonyms & Secondary IDs ( 9 )
Reported As
Symbol Synonym	CG5657 (Dekkers et al., 2004, Perkins et al., 2009) DmSCG-β (Greener and Roberts, 2000) dscgβ (Hashimoto and Yamaguchi, 2006, Hashimoto and Yamaguchi, 2007, Hashimoto and Yamaguchi, 2006) Scgbeta (Driscoll and Gerstbrein, 2003) Scgβ   scg-β (Johnson et al., 2010)
Name Synonym	Sarcoglycan β (Greener, 2000.6.14) β-sarcoglycan (Hashimoto and Yamaguchi, 2007) β-sarcolgycan (Hashimoto and Yamaguchi, 2006)
Secondary FlyBase IDs
References ( 17 )
Research paper	Johnson et al., 2010, PLoS Genet. 6(3): e1000872 PPS, a Large Multidomain Protein, Functions with Sex-Lethal to Regulate Alternative Splicing in Drosophila. [FBrf0210202] Hashimoto and Yamaguchi, 2006, Biochem. biophys. Res. Commun. 348(1): 212--221 Genetic link between beta-sarcoglycan and the Egfr signaling pathway. [FBrf0194118] Dekkers et al., 2004, Gene Expression Patterns 4(2): 153--159 Embryonic expression patterns of the Drosophila dystrophin-associated glycoprotein complex orthologs. [FBrf0174640]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Driscoll and Gerstbrein, 2003, Nature Rev. Genet. 4(3): Dying for a cause: invertebrate genetics takes on human neurodegeneration. [FBrf0159901]
Review	Pilgram et al., 2010, Molec. Neurobiol. 41(1): 1--21 The roles of the dystrophin-associated glycoprotein complex at the synapse. [FBrf0212855] Greener and Roberts, 2000, FEBS Lett. 482(1-2): 13--18 Conservation of components of the dystrophin complex in Drosophila. [FBrf0129834]
Personal communication to FlyBase	Perkins et al., 2009, Update to TRiP stock collection. Update to TRiP stock collection. [FBrf0208864] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
Abstract	Hashimoto and Yamaguchi, 2007, Europ. Dros. Res. Conf. 20: A032 GENETIC LINK BETWEEN BETA-SARCOGLYCAN AND EGFR SIGNALING IN DROSOPHILA. [FBrf0199596] Hashimoto and Yamaguchi, 2006, A. Dros. Res. Conf. 47: 826C Knocking down of scgb in Drosophila eye imaginal discs induces severe morphological aberration in adult compound eyes. [FBrf0188813]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946]
DNA/RNA sequence record	Greener, 2000.6.14, GenBank/EMBL/DDBJ: AF277392 Drosophila melanogaster beta-sarcoglycan-like protein SCG-BETA (Scg-Beta) mRNA, partial cds. [FBrf0130694]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]