General Information Symbol Dmel\ CG17202Species D. melanogaster Name Annotation symbol CG17202 Feature type protein_coding_gene FlyBase ID FBgn0038043 Gene Model Status Current Stock availability 3 publicly
available Genomic Location Chromosome (arm) 3R Recombination map Cytogenetic map 87B9-87B9 Sequence location 3R:8,248,490..8,249,328 [+]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information This gene is referred to in FlyBase by the symbol
Dmel\CG17202 (FBgn0038043). It is a protein_coding_gene from
Drosophila melanogaster . An electronic pipeline based on InterPro domains suggests that it has the
molecular function : transcription coactivator activity; cAMP-dependent protein kinase regulator activity. An electronic pipeline based on InterPro domains suggests that it is involved in the
biological process : signal transduction; regulation of transcription, DNA-dependent.
4 alleles are reported . No phenotypic data is available. It has
one annotated transcript and
one annotated polypeptide .
Protein features are: Associate of Myc 1; cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, adult midgut, larval hindgut, larval Malpighian tubules, larval fat body, larval salivary gland, larval trachea, adult ovary, adult male reproductive system, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1635603_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG17202. Gene sequence location is
3R:8248490..8249328 .
User Contributed Data
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FB2013_03
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.50
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: maternally deposited
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
397.25
Larval Midgut
94
Larval Hindgut
106.7
Larval Malpighian Tubules
102
Larval Fat Body
167.5
Larval Salivary Gland
210.9
Larval Trachea
244.275
Larval Carcass
113.675
Adult Head
98.2
Adult Eye
174.35
Adult Brain
191.1
Adult Thoracic-Abdominal Ganglion
134.5
Adult Crop
57.4
Adult Midgut
101.8
Adult Hindgut
83.7
Adult Malpighian Tubules
51.9
Adult Fat Body
76.9
Adult Salivary Gland
92.1
Adult Heart
78.05
Adult VirginFemale Spermatheca
48.2
Adult InseminatedFemale Spermatheca
52.5
Adult Ovary
456.6
Adult Testis
251.2
Adult Male Accessory Gland
317.3
Adult Carcass
61.7
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
397.25
Larval Midgut
94
Larval Hindgut
106.7
Larval Malpighian Tubules
102
Larval Fat Body
167.5
Larval Salivary Gland
210.9
Larval Trachea
244.275
Larval Carcass
113.675
Adult Head
98.2
Adult Eye
174.35
Adult Brain
191.1
Adult Thoracic-Abdominal Ganglion
134.5
Adult Crop
57.4
Adult Midgut
101.8
Adult Hindgut
83.7
Adult Malpighian Tubules
51.9
Adult Fat Body
76.9
Adult Salivary Gland
92.1
Adult Heart
78.05
Adult VirginFemale Spermatheca
48.2
Adult InseminatedFemale Spermatheca
52.5
Adult Ovary
456.6
Adult Testis
251.2
Adult Male Accessory Gland
317.3
Adult Carcass
61.7
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
397.25
Larval Midgut
94
Larval Hindgut
106.7
Larval Malpighian Tubules
102
Larval Fat Body
167.5
Larval Salivary Gland
210.9
Larval Trachea
244.275
Larval Carcass
113.675
Adult Head
98.2
Adult Eye
174.35
Adult Brain
191.1
Adult Thoracic-Abdominal Ganglion
134.5
Adult Crop
57.4
Adult Midgut
101.8
Adult Hindgut
83.7
Adult Malpighian Tubules
51.9
Adult Fat Body
76.9
Adult Salivary Gland
92.1
Adult Heart
78.05
Adult VirginFemale Spermatheca
48.2
Adult InseminatedFemale Spermatheca
52.5
Adult Ovary
456.6
Adult Testis
251.2
Adult Male Accessory Gland
317.3
Adult Carcass
61.7
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
397.25
Larval Midgut
94
Larval Hindgut
106.7
Larval Malpighian Tubules
102
Larval Fat Body
167.5
Larval Salivary Gland
210.9
Larval Trachea
244.275
Larval Carcass
113.675
Adult Head
98.2
Adult Eye
174.35
Adult Brain
191.1
Adult Thoracic-Abdominal Ganglion
134.5
Adult Crop
57.4
Adult Midgut
101.8
Adult Hindgut
83.7
Adult Malpighian Tubules
51.9
Adult Fat Body
76.9
Adult Salivary Gland
92.1
Adult Heart
78.05
Adult VirginFemale Spermatheca
48.2
Adult InseminatedFemale Spermatheca
52.5
Adult Ovary
456.6
Adult Testis
251.2
Adult Male Accessory Gland
317.3
Adult Carcass
61.7
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
397.25
Larval Midgut
94
Larval Hindgut
106.7
Larval Malpighian Tubules
102
Larval Fat Body
167.5
Larval Salivary Gland
210.9
Larval Trachea
244.275
Larval Carcass
113.675
Adult Head
98.2
Adult Eye
174.35
Adult Brain
191.1
Adult Thoracic-Abdominal Ganglion
134.5
Adult Crop
57.4
Adult Midgut
101.8
Adult Hindgut
83.7
Adult Malpighian Tubules
51.9
Adult Fat Body
76.9
Adult Salivary Gland
92.1
Adult Heart
78.05
Adult VirginFemale Spermatheca
48.2
Adult InseminatedFemale Spermatheca
52.5
Adult Ovary
456.6
Adult Testis
251.2
Adult Male Accessory Gland
317.3
Adult Carcass
61.7
Expression Level Scale
None
Low
Moderate
High
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
397.25
Larval Midgut
94
Larval Hindgut
106.7
Larval Malpighian Tubules
102
Larval Fat Body
167.5
Larval Salivary Gland
210.9
Larval Trachea
244.275
Larval Carcass
113.675
Adult Head
98.2
Adult Eye
174.35
Adult Brain
191.1
Adult Thoracic-Abdominal Ganglion
134.5
Adult Crop
57.4
Adult Midgut
101.8
Adult Hindgut
83.7
Adult Malpighian Tubules
51.9
Adult Fat Body
76.9
Adult Salivary Gland
92.1
Adult Heart
78.05
Adult VirginFemale Spermatheca
48.2
Adult InseminatedFemale Spermatheca
52.5
Adult Ovary
456.6
Adult Testis
251.2
Adult Male Accessory Gland
317.3
Adult Carcass
61.7
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
397.25
Larval Midgut
94
Larval Hindgut
106.7
Larval Malpighian Tubules
102
Larval Fat Body
167.5
Larval Salivary Gland
210.9
Larval Trachea
244.275
Larval Carcass
113.675
Adult Head
98.2
Adult Eye
174.35
Adult Brain
191.1
Adult Thoracic-Abdominal Ganglion
134.5
Adult Crop
57.4
Adult Midgut
101.8
Adult Hindgut
83.7
Adult Malpighian Tubules
51.9
Adult Fat Body
76.9
Adult Salivary Gland
92.1
Adult Heart
78.05
Adult VirginFemale Spermatheca
48.2
Adult InseminatedFemale Spermatheca
52.5
Adult Ovary
456.6
Adult Testis
251.2
Adult Male Accessory Gland
317.3
Adult Carcass
61.7
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
397.25
Larval Midgut
94
Larval Hindgut
106.7
Larval Malpighian Tubules
102
Larval Fat Body
167.5
Larval Salivary Gland
210.9
Larval Trachea
244.275
Larval Carcass
113.675
Adult Head
98.2
Adult Eye
174.35
Adult Brain
191.1
Adult Thoracic-Abdominal Ganglion
134.5
Adult Crop
57.4
Adult Midgut
101.8
Adult Hindgut
83.7
Adult Malpighian Tubules
51.9
Adult Fat Body
76.9
Adult Salivary Gland
92.1
Adult Heart
78.05
Adult VirginFemale Spermatheca
48.2
Adult InseminatedFemale Spermatheca
52.5
Adult Ovary
456.6
Adult Testis
251.2
Adult Male Accessory Gland
317.3
Adult Carcass
61.7
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
98.2
NA
Eye
174.35
NA
Brain
191.1
397.25
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
134.5
NA
Crop
57.4
94
Midgut
101.8
106.7
Hindgut
83.7
102
Malpighian Tubules
51.9
167.5
Fat Body
76.9
210.9
Salivary Gland
92.1
NA
Heart
78.05
244.275
Trachea
NA
NA
VirginFemale Spermatheca
48.2
NA
InseminatedFemale Spermatheca
52.5
NA
Ovary
456.6
NA
Testis
251.2
NA
Male Accessory Gland
317.3
113.675
Carcass
61.7
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
134
central nervous system, larvae L3
165
central nervous system, pupae P8
52
head, virgin 1-day female
26
head, virgin 4-day female
21
head, virgin 20-day female
18
head, mated 1-day female
29
head, mated 4-day female
23
head, mated 20-day female
20
head, mated 1-day male
31
head, mated 4-day male
37
head, mated 20-day male
45
salivary gland, larvae L3 wandering
23
salivary gland, white prepupae
41
digestive system, larvae L3 wandering
59
digestive system, 1-day adult
35
digestive system, 4-day adult
43
digestive system, 20-day adult
36
fat body, larvae L3 wandering
30
fat body, white prepupae
75
fat body, pupae P8
199
carcass, larvae L3 wandering
87
carcass, 1-day adult
16
carcass, 4-day adult
26
carcass, 20-day adult
25
ovary, virgin 4-day female
249
ovary, mated 4-day female
244
testis, mated 4-day male
238
accessory gland, mated 4-day male
76
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(134)
central nervous system, larvae L3
(165)
central nervous system, pupae P8
(52)
head, virgin 1-day female
26
head, virgin 4-day female
21
head, virgin 20-day female
18
head, mated 1-day female
(29)
head, mated 4-day female
23
head, mated 20-day female
20
head, mated 1-day male
(31)
head, mated 4-day male
(37)
head, mated 20-day male
(45)
salivary gland, larvae L3 wandering
23
salivary gland, white prepupae
(41)
digestive system, larvae L3 wandering
(59)
digestive system, 1-day adult
(35)
digestive system, 4-day adult
(43)
digestive system, 20-day adult
(36)
fat body, larvae L3 wandering
(30)
fat body, white prepupae
(75)
fat body, pupae P8
(199)
carcass, larvae L3 wandering
(87)
carcass, 1-day adult
16
carcass, 4-day adult
26
carcass, 20-day adult
25
ovary, virgin 4-day female
(249)
ovary, mated 4-day female
(244)
testis, mated 4-day male
(238)
accessory gland, mated 4-day male
(76)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(134)
central nervous system, larvae L3
(165)
central nervous system, pupae P8
52
head, virgin 1-day female
26
head, virgin 4-day female
21
head, virgin 20-day female
18
head, mated 1-day female
29
head, mated 4-day female
23
head, mated 20-day female
20
head, mated 1-day male
31
head, mated 4-day male
37
head, mated 20-day male
45
salivary gland, larvae L3 wandering
23
salivary gland, white prepupae
41
digestive system, larvae L3 wandering
59
digestive system, 1-day adult
35
digestive system, 4-day adult
43
digestive system, 20-day adult
36
fat body, larvae L3 wandering
30
fat body, white prepupae
75
fat body, pupae P8
(199)
carcass, larvae L3 wandering
87
carcass, 1-day adult
16
carcass, 4-day adult
26
carcass, 20-day adult
25
ovary, virgin 4-day female
(249)
ovary, mated 4-day female
(244)
testis, mated 4-day male
(238)
accessory gland, mated 4-day male
76
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
134
central nervous system, larvae L3
165
central nervous system, pupae P8
52
head, virgin 1-day female
26
head, virgin 4-day female
21
head, virgin 20-day female
18
head, mated 1-day female
29
head, mated 4-day female
23
head, mated 20-day female
20
head, mated 1-day male
31
head, mated 4-day male
37
head, mated 20-day male
45
salivary gland, larvae L3 wandering
23
salivary gland, white prepupae
41
digestive system, larvae L3 wandering
59
digestive system, 1-day adult
35
digestive system, 4-day adult
43
digestive system, 20-day adult
36
fat body, larvae L3 wandering
30
fat body, white prepupae
75
fat body, pupae P8
199
carcass, larvae L3 wandering
87
carcass, 1-day adult
16
carcass, 4-day adult
26
carcass, 20-day adult
25
ovary, virgin 4-day female
249
ovary, mated 4-day female
244
testis, mated 4-day male
238
accessory gland, mated 4-day male
76
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
134
central nervous system, larvae L3
165
central nervous system, pupae P8
52
head, virgin 1-day female
26
head, virgin 4-day female
21
head, virgin 20-day female
18
head, mated 1-day female
29
head, mated 4-day female
23
head, mated 20-day female
20
head, mated 1-day male
31
head, mated 4-day male
37
head, mated 20-day male
45
salivary gland, larvae L3 wandering
23
salivary gland, white prepupae
41
digestive system, larvae L3 wandering
59
digestive system, 1-day adult
35
digestive system, 4-day adult
43
digestive system, 20-day adult
36
fat body, larvae L3 wandering
30
fat body, white prepupae
75
fat body, pupae P8
199
carcass, larvae L3 wandering
87
carcass, 1-day adult
16
carcass, 4-day adult
26
carcass, 20-day adult
25
ovary, virgin 4-day female
249
ovary, mated 4-day female
244
testis, mated 4-day male
238
accessory gland, mated 4-day male
76
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(134)
central nervous system, larvae L3
(165)
central nervous system, pupae P8
(52)
head, virgin 1-day female
26
head, virgin 4-day female
21
head, virgin 20-day female
18
head, mated 1-day female
29
head, mated 4-day female
23
head, mated 20-day female
20
head, mated 1-day male
31
head, mated 4-day male
(37)
head, mated 20-day male
(45)
salivary gland, larvae L3 wandering
23
salivary gland, white prepupae
(41)
digestive system, larvae L3 wandering
(59)
digestive system, 1-day adult
(35)
digestive system, 4-day adult
(43)
digestive system, 20-day adult
(36)
fat body, larvae L3 wandering
30
fat body, white prepupae
(75)
fat body, pupae P8
(199)
carcass, larvae L3 wandering
(87)
carcass, 1-day adult
16
carcass, 4-day adult
26
carcass, 20-day adult
25
ovary, virgin 4-day female
(249)
ovary, mated 4-day female
(244)
testis, mated 4-day male
(238)
accessory gland, mated 4-day male
(76)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
134
central nervous system, larvae L3
(165)
central nervous system, pupae P8
52
head, virgin 1-day female
26
head, virgin 4-day female
21
head, virgin 20-day female
18
head, mated 1-day female
29
head, mated 4-day female
23
head, mated 20-day female
20
head, mated 1-day male
31
head, mated 4-day male
37
head, mated 20-day male
45
salivary gland, larvae L3 wandering
23
salivary gland, white prepupae
41
digestive system, larvae L3 wandering
59
digestive system, 1-day adult
35
digestive system, 4-day adult
43
digestive system, 20-day adult
36
fat body, larvae L3 wandering
30
fat body, white prepupae
75
fat body, pupae P8
(199)
carcass, larvae L3 wandering
87
carcass, 1-day adult
16
carcass, 4-day adult
26
carcass, 20-day adult
25
ovary, virgin 4-day female
(249)
ovary, mated 4-day female
(244)
testis, mated 4-day male
(238)
accessory gland, mated 4-day male
76
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
134
central nervous system, larvae L3
165
central nervous system, pupae P8
52
head, virgin 1-day female
26
head, virgin 4-day female
21
head, virgin 20-day female
18
head, mated 1-day female
29
head, mated 4-day female
23
head, mated 20-day female
20
head, mated 1-day male
31
head, mated 4-day male
37
head, mated 20-day male
45
salivary gland, larvae L3 wandering
23
salivary gland, white prepupae
41
digestive system, larvae L3 wandering
59
digestive system, 1-day adult
35
digestive system, 4-day adult
43
digestive system, 20-day adult
36
fat body, larvae L3 wandering
30
fat body, white prepupae
75
fat body, pupae P8
199
carcass, larvae L3 wandering
87
carcass, 1-day adult
16
carcass, 4-day adult
26
carcass, 20-day adult
25
ovary, virgin 4-day female
249
ovary, mated 4-day female
244
testis, mated 4-day male
238
accessory gland, mated 4-day male
76
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
141
embryo 02-04hr
11
embryo 04-06hr
24
embryo 06-08hr
50
embryo 08-10hr
47
embryo 10-12hr
45
embryo 12-14hr
25
embryo 14-16hr
23
embryo 16-18hr
19
embryo 18-20hr
23
embryo 20-22hr
18
embryo 22-24hr
14
larva L1
22
larva L2
27
larva L3 12hr old
28
larva L3 puffstage 1-2
35
larva L3 puffstage 3-6
57
larva L3 puffstage 7-9
63
white prepupae new
64
white prepupae 12hr
58
white prepupae 24hr
69
pupae 2d postWPP
44
pupae 3d postWPP
26
pupae 4d postWPP
23
adult male 01day
29
adult male 05day
45
adult male 30day
36
adult female 01day
63
adult female 05day
116
adult female 30day
129
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(141)
embryo 02-04hr
11
embryo 04-06hr
24
embryo 06-08hr
(50)
embryo 08-10hr
(47)
embryo 10-12hr
(45)
embryo 12-14hr
25
embryo 14-16hr
23
embryo 16-18hr
19
embryo 18-20hr
23
embryo 20-22hr
18
embryo 22-24hr
14
larva L1
22
larva L2
(27)
larva L3 12hr old
(28)
larva L3 puffstage 1-2
(35)
larva L3 puffstage 3-6
(57)
larva L3 puffstage 7-9
(63)
white prepupae new
(64)
white prepupae 12hr
(58)
white prepupae 24hr
(69)
pupae 2d postWPP
(44)
pupae 3d postWPP
26
pupae 4d postWPP
23
adult male 01day
(29)
adult male 05day
(45)
adult male 30day
(36)
adult female 01day
(63)
adult female 05day
(116)
adult female 30day
(129)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
(141)
embryo 02-04hr
11
embryo 04-06hr
24
embryo 06-08hr
50
embryo 08-10hr
47
embryo 10-12hr
45
embryo 12-14hr
25
embryo 14-16hr
23
embryo 16-18hr
19
embryo 18-20hr
23
embryo 20-22hr
18
embryo 22-24hr
14
larva L1
22
larva L2
27
larva L3 12hr old
28
larva L3 puffstage 1-2
35
larva L3 puffstage 3-6
57
larva L3 puffstage 7-9
63
white prepupae new
64
white prepupae 12hr
58
white prepupae 24hr
69
pupae 2d postWPP
44
pupae 3d postWPP
26
pupae 4d postWPP
23
adult male 01day
29
adult male 05day
45
adult male 30day
36
adult female 01day
63
adult female 05day
(116)
adult female 30day
(129)
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
141
embryo 02-04hr
11
embryo 04-06hr
24
embryo 06-08hr
50
embryo 08-10hr
47
embryo 10-12hr
45
embryo 12-14hr
25
embryo 14-16hr
23
embryo 16-18hr
19
embryo 18-20hr
23
embryo 20-22hr
18
embryo 22-24hr
14
larva L1
22
larva L2
27
larva L3 12hr old
28
larva L3 puffstage 1-2
35
larva L3 puffstage 3-6
57
larva L3 puffstage 7-9
63
white prepupae new
64
white prepupae 12hr
58
white prepupae 24hr
69
pupae 2d postWPP
44
pupae 3d postWPP
26
pupae 4d postWPP
23
adult male 01day
29
adult male 05day
45
adult male 30day
36
adult female 01day
63
adult female 05day
116
adult female 30day
129
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
141
embryo 02-04hr
11
embryo 04-06hr
24
embryo 06-08hr
50
embryo 08-10hr
47
embryo 10-12hr
45
embryo 12-14hr
25
embryo 14-16hr
23
embryo 16-18hr
19
embryo 18-20hr
23
embryo 20-22hr
18
embryo 22-24hr
14
larva L1
22
larva L2
27
larva L3 12hr old
28
larva L3 puffstage 1-2
35
larva L3 puffstage 3-6
57
larva L3 puffstage 7-9
63
white prepupae new
64
white prepupae 12hr
58
white prepupae 24hr
69
pupae 2d postWPP
44
pupae 3d postWPP
26
pupae 4d postWPP
23
adult male 01day
29
adult male 05day
45
adult male 30day
36
adult female 01day
63
adult female 05day
116
adult female 30day
129
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(141)
embryo 02-04hr
11
embryo 04-06hr
24
embryo 06-08hr
(50)
embryo 08-10hr
(47)
embryo 10-12hr
(45)
embryo 12-14hr
25
embryo 14-16hr
23
embryo 16-18hr
19
embryo 18-20hr
23
embryo 20-22hr
18
embryo 22-24hr
14
larva L1
22
larva L2
27
larva L3 12hr old
28
larva L3 puffstage 1-2
(35)
larva L3 puffstage 3-6
(57)
larva L3 puffstage 7-9
(63)
white prepupae new
(64)
white prepupae 12hr
(58)
white prepupae 24hr
(69)
pupae 2d postWPP
(44)
pupae 3d postWPP
26
pupae 4d postWPP
23
adult male 01day
29
adult male 05day
(45)
adult male 30day
(36)
adult female 01day
(63)
adult female 05day
(116)
adult female 30day
(129)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
141
embryo 02-04hr
11
embryo 04-06hr
24
embryo 06-08hr
50
embryo 08-10hr
47
embryo 10-12hr
45
embryo 12-14hr
25
embryo 14-16hr
23
embryo 16-18hr
19
embryo 18-20hr
23
embryo 20-22hr
18
embryo 22-24hr
14
larva L1
22
larva L2
27
larva L3 12hr old
28
larva L3 puffstage 1-2
35
larva L3 puffstage 3-6
57
larva L3 puffstage 7-9
63
white prepupae new
64
white prepupae 12hr
58
white prepupae 24hr
69
pupae 2d postWPP
44
pupae 3d postWPP
26
pupae 4d postWPP
23
adult male 01day
29
adult male 05day
45
adult male 30day
36
adult female 01day
63
adult female 05day
116
adult female 30day
129
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
141
embryo 02-04hr
11
embryo 04-06hr
24
embryo 06-08hr
50
embryo 08-10hr
47
embryo 10-12hr
45
embryo 12-14hr
25
embryo 14-16hr
23
embryo 16-18hr
19
embryo 18-20hr
23
embryo 20-22hr
18
embryo 22-24hr
14
larva L1
22
larva L2
27
larva L3 12hr old
28
larva L3 puffstage 1-2
35
larva L3 puffstage 3-6
57
larva L3 puffstage 7-9
63
white prepupae new
64
white prepupae 12hr
58
white prepupae 24hr
69
pupae 2d postWPP
44
pupae 3d postWPP
26
pupae 4d postWPP
23
adult male 01day
29
adult male 05day
45
adult male 30day
36
adult female 01day
63
adult female 05day
116
adult female 30day
129
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
81
Schneider line 2 Sg4
72
embryonic 1182-4H
57
embryonic GM2
64
embryonic Kc167
23
embryonic S1
138
embryonic S3
73
leg disc CME L1
121
wing disc CME-W2
94
wing disc ML-DmD8
80
wing disc ML-DmD9
88
wing disc ML-DmD16-c3
105
wing disc ML-DmD21
204
wing disc ML-DmD32
104
haltere disc ML-DmD17-c3
87
eye-antennal disc ML-DmD11
103
antennal disc ML-DmD20-c5
97
mixed discs ML-DmD4-c1
100
CNS ML-DmBG1-c1
112
CNS ML-DmBG2-c2
63
tumorous blood cells mbn2
49
ovary fGS/OSS
145
ovary OSC
200
ovary OSS
131
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(81)
Schneider line 2 Sg4
(72)
embryonic 1182-4H
(57)
embryonic GM2
(64)
embryonic Kc167
23
embryonic S1
(138)
embryonic S3
(73)
leg disc CME L1
(121)
wing disc CME-W2
(94)
wing disc ML-DmD8
(80)
wing disc ML-DmD9
(88)
wing disc ML-DmD16-c3
(105)
wing disc ML-DmD21
(204)
wing disc ML-DmD32
(104)
haltere disc ML-DmD17-c3
(87)
eye-antennal disc ML-DmD11
(103)
antennal disc ML-DmD20-c5
(97)
mixed discs ML-DmD4-c1
(100)
CNS ML-DmBG1-c1
(112)
CNS ML-DmBG2-c2
(63)
tumorous blood cells mbn2
(49)
ovary fGS/OSS
(145)
ovary OSC
(200)
ovary OSS
(131)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
81
Schneider line 2 Sg4
72
embryonic 1182-4H
57
embryonic GM2
64
embryonic Kc167
23
embryonic S1
(138)
embryonic S3
73
leg disc CME L1
(121)
wing disc CME-W2
94
wing disc ML-DmD8
80
wing disc ML-DmD9
88
wing disc ML-DmD16-c3
105
wing disc ML-DmD21
(204)
wing disc ML-DmD32
104
haltere disc ML-DmD17-c3
87
eye-antennal disc ML-DmD11
103
antennal disc ML-DmD20-c5
97
mixed discs ML-DmD4-c1
100
CNS ML-DmBG1-c1
(112)
CNS ML-DmBG2-c2
63
tumorous blood cells mbn2
49
ovary fGS/OSS
(145)
ovary OSC
(200)
ovary OSS
(131)
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
81
Schneider line 2 Sg4
72
embryonic 1182-4H
57
embryonic GM2
64
embryonic Kc167
23
embryonic S1
138
embryonic S3
73
leg disc CME L1
121
wing disc CME-W2
94
wing disc ML-DmD8
80
wing disc ML-DmD9
88
wing disc ML-DmD16-c3
105
wing disc ML-DmD21
204
wing disc ML-DmD32
104
haltere disc ML-DmD17-c3
87
eye-antennal disc ML-DmD11
103
antennal disc ML-DmD20-c5
97
mixed discs ML-DmD4-c1
100
CNS ML-DmBG1-c1
112
CNS ML-DmBG2-c2
63
tumorous blood cells mbn2
49
ovary fGS/OSS
145
ovary OSC
200
ovary OSS
131
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
81
Schneider line 2 Sg4
72
embryonic 1182-4H
57
embryonic GM2
64
embryonic Kc167
23
embryonic S1
138
embryonic S3
73
leg disc CME L1
121
wing disc CME-W2
94
wing disc ML-DmD8
80
wing disc ML-DmD9
88
wing disc ML-DmD16-c3
105
wing disc ML-DmD21
204
wing disc ML-DmD32
104
haltere disc ML-DmD17-c3
87
eye-antennal disc ML-DmD11
103
antennal disc ML-DmD20-c5
97
mixed discs ML-DmD4-c1
100
CNS ML-DmBG1-c1
112
CNS ML-DmBG2-c2
63
tumorous blood cells mbn2
49
ovary fGS/OSS
145
ovary OSC
200
ovary OSS
131
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(81)
Schneider line 2 Sg4
(72)
embryonic 1182-4H
(57)
embryonic GM2
(64)
embryonic Kc167
23
embryonic S1
(138)
embryonic S3
(73)
leg disc CME L1
(121)
wing disc CME-W2
(94)
wing disc ML-DmD8
(80)
wing disc ML-DmD9
(88)
wing disc ML-DmD16-c3
(105)
wing disc ML-DmD21
(204)
wing disc ML-DmD32
(104)
haltere disc ML-DmD17-c3
(87)
eye-antennal disc ML-DmD11
(103)
antennal disc ML-DmD20-c5
(97)
mixed discs ML-DmD4-c1
(100)
CNS ML-DmBG1-c1
(112)
CNS ML-DmBG2-c2
(63)
tumorous blood cells mbn2
(49)
ovary fGS/OSS
(145)
ovary OSC
(200)
ovary OSS
(131)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
81
Schneider line 2 Sg4
72
embryonic 1182-4H
57
embryonic GM2
64
embryonic Kc167
23
embryonic S1
138
embryonic S3
73
leg disc CME L1
121
wing disc CME-W2
94
wing disc ML-DmD8
80
wing disc ML-DmD9
88
wing disc ML-DmD16-c3
105
wing disc ML-DmD21
(204)
wing disc ML-DmD32
104
haltere disc ML-DmD17-c3
87
eye-antennal disc ML-DmD11
103
antennal disc ML-DmD20-c5
97
mixed discs ML-DmD4-c1
100
CNS ML-DmBG1-c1
112
CNS ML-DmBG2-c2
63
tumorous blood cells mbn2
49
ovary fGS/OSS
(145)
ovary OSC
(200)
ovary OSS
131
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
81
Schneider line 2 Sg4
72
embryonic 1182-4H
57
embryonic GM2
64
embryonic Kc167
23
embryonic S1
138
embryonic S3
73
leg disc CME L1
121
wing disc CME-W2
94
wing disc ML-DmD8
80
wing disc ML-DmD9
88
wing disc ML-DmD16-c3
105
wing disc ML-DmD21
204
wing disc ML-DmD32
104
haltere disc ML-DmD17-c3
87
eye-antennal disc ML-DmD11
103
antennal disc ML-DmD20-c5
97
mixed discs ML-DmD4-c1
100
CNS ML-DmBG1-c1
112
CNS ML-DmBG2-c2
63
tumorous blood cells mbn2
49
ovary fGS/OSS
145
ovary OSC
200
ovary OSS
131
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
93
cold shock, 4-day adult
66
heat shock, 4-day adult
73
Cadmium 50 mM 6 hrs, larvae L3
33
Cadmium 50 mM 12 hrs, larvae L3
45
Cadmium 50 mM 48 hrs, 4-day adult
69
Cadmium 100 mM 48 hrs, 4-day adult
165
Copper 0.5 mM 12 hrs, larvae L3
48
Copper 15 mM 48 hrs, 4-day adult
125
Zinc 5 mM 12 hrs, larvae L3
39
Zinc 4.5 mM 48 hrs, 4-day adult
56
Ethanol 2.5% 3 hrs, larvae L3
142
Ethanol 5% 3 hrs, larvae L3
26
Ethanol 10% 3 hrs, larvae L3
32
Caffeine 1.5 mg/ml 4 hrs, larvae L3
24
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
166
Caffeine 25 mg/ml 48 hrs, 4-day adult
76
Paraquat 5 mM 48 hrs, 4-day adult
120
Paraquat 10 mM 48 hrs, 4-day adult
99
Rotenone 2 μg 12 hrs, larvae L3
33
Rotenone 8 μg 12 hrs, larvae L3
36
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
(93)
cold shock, 4-day adult
(66)
heat shock, 4-day adult
(73)
Cadmium 50 mM 6 hrs, larvae L3
(33)
Cadmium 50 mM 12 hrs, larvae L3
(45)
Cadmium 50 mM 48 hrs, 4-day adult
(69)
Cadmium 100 mM 48 hrs, 4-day adult
(165)
Copper 0.5 mM 12 hrs, larvae L3
(48)
Copper 15 mM 48 hrs, 4-day adult
(125)
Zinc 5 mM 12 hrs, larvae L3
(39)
Zinc 4.5 mM 48 hrs, 4-day adult
(56)
Ethanol 2.5% 3 hrs, larvae L3
(142)
Ethanol 5% 3 hrs, larvae L3
26
Ethanol 10% 3 hrs, larvae L3
(32)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
24
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(166)
Caffeine 25 mg/ml 48 hrs, 4-day adult
(76)
Paraquat 5 mM 48 hrs, 4-day adult
(120)
Paraquat 10 mM 48 hrs, 4-day adult
(99)
Rotenone 2 μg 12 hrs, larvae L3
(33)
Rotenone 8 μg 12 hrs, larvae L3
(36)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
93
cold shock, 4-day adult
66
heat shock, 4-day adult
73
Cadmium 50 mM 6 hrs, larvae L3
33
Cadmium 50 mM 12 hrs, larvae L3
45
Cadmium 50 mM 48 hrs, 4-day adult
69
Cadmium 100 mM 48 hrs, 4-day adult
(165)
Copper 0.5 mM 12 hrs, larvae L3
48
Copper 15 mM 48 hrs, 4-day adult
(125)
Zinc 5 mM 12 hrs, larvae L3
39
Zinc 4.5 mM 48 hrs, 4-day adult
56
Ethanol 2.5% 3 hrs, larvae L3
(142)
Ethanol 5% 3 hrs, larvae L3
26
Ethanol 10% 3 hrs, larvae L3
32
Caffeine 1.5 mg/ml 4 hrs, larvae L3
24
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(166)
Caffeine 25 mg/ml 48 hrs, 4-day adult
76
Paraquat 5 mM 48 hrs, 4-day adult
(120)
Paraquat 10 mM 48 hrs, 4-day adult
99
Rotenone 2 μg 12 hrs, larvae L3
33
Rotenone 8 μg 12 hrs, larvae L3
36
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
93
cold shock, 4-day adult
66
heat shock, 4-day adult
73
Cadmium 50 mM 6 hrs, larvae L3
33
Cadmium 50 mM 12 hrs, larvae L3
45
Cadmium 50 mM 48 hrs, 4-day adult
69
Cadmium 100 mM 48 hrs, 4-day adult
165
Copper 0.5 mM 12 hrs, larvae L3
48
Copper 15 mM 48 hrs, 4-day adult
125
Zinc 5 mM 12 hrs, larvae L3
39
Zinc 4.5 mM 48 hrs, 4-day adult
56
Ethanol 2.5% 3 hrs, larvae L3
142
Ethanol 5% 3 hrs, larvae L3
26
Ethanol 10% 3 hrs, larvae L3
32
Caffeine 1.5 mg/ml 4 hrs, larvae L3
24
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
166
Caffeine 25 mg/ml 48 hrs, 4-day adult
76
Paraquat 5 mM 48 hrs, 4-day adult
120
Paraquat 10 mM 48 hrs, 4-day adult
99
Rotenone 2 μg 12 hrs, larvae L3
33
Rotenone 8 μg 12 hrs, larvae L3
36
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
93
cold shock, 4-day adult
66
heat shock, 4-day adult
73
Cadmium 50 mM 6 hrs, larvae L3
33
Cadmium 50 mM 12 hrs, larvae L3
45
Cadmium 50 mM 48 hrs, 4-day adult
69
Cadmium 100 mM 48 hrs, 4-day adult
165
Copper 0.5 mM 12 hrs, larvae L3
48
Copper 15 mM 48 hrs, 4-day adult
125
Zinc 5 mM 12 hrs, larvae L3
39
Zinc 4.5 mM 48 hrs, 4-day adult
56
Ethanol 2.5% 3 hrs, larvae L3
142
Ethanol 5% 3 hrs, larvae L3
26
Ethanol 10% 3 hrs, larvae L3
32
Caffeine 1.5 mg/ml 4 hrs, larvae L3
24
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
166
Caffeine 25 mg/ml 48 hrs, 4-day adult
76
Paraquat 5 mM 48 hrs, 4-day adult
120
Paraquat 10 mM 48 hrs, 4-day adult
99
Rotenone 2 μg 12 hrs, larvae L3
33
Rotenone 8 μg 12 hrs, larvae L3
36
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
(93)
cold shock, 4-day adult
(66)
heat shock, 4-day adult
(73)
Cadmium 50 mM 6 hrs, larvae L3
(33)
Cadmium 50 mM 12 hrs, larvae L3
(45)
Cadmium 50 mM 48 hrs, 4-day adult
(69)
Cadmium 100 mM 48 hrs, 4-day adult
(165)
Copper 0.5 mM 12 hrs, larvae L3
(48)
Copper 15 mM 48 hrs, 4-day adult
(125)
Zinc 5 mM 12 hrs, larvae L3
(39)
Zinc 4.5 mM 48 hrs, 4-day adult
(56)
Ethanol 2.5% 3 hrs, larvae L3
(142)
Ethanol 5% 3 hrs, larvae L3
26
Ethanol 10% 3 hrs, larvae L3
32
Caffeine 1.5 mg/ml 4 hrs, larvae L3
24
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(166)
Caffeine 25 mg/ml 48 hrs, 4-day adult
(76)
Paraquat 5 mM 48 hrs, 4-day adult
(120)
Paraquat 10 mM 48 hrs, 4-day adult
(99)
Rotenone 2 μg 12 hrs, larvae L3
(33)
Rotenone 8 μg 12 hrs, larvae L3
(36)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
93
cold shock, 4-day adult
66
heat shock, 4-day adult
73
Cadmium 50 mM 6 hrs, larvae L3
33
Cadmium 50 mM 12 hrs, larvae L3
45
Cadmium 50 mM 48 hrs, 4-day adult
69
Cadmium 100 mM 48 hrs, 4-day adult
(165)
Copper 0.5 mM 12 hrs, larvae L3
48
Copper 15 mM 48 hrs, 4-day adult
125
Zinc 5 mM 12 hrs, larvae L3
39
Zinc 4.5 mM 48 hrs, 4-day adult
56
Ethanol 2.5% 3 hrs, larvae L3
142
Ethanol 5% 3 hrs, larvae L3
26
Ethanol 10% 3 hrs, larvae L3
32
Caffeine 1.5 mg/ml 4 hrs, larvae L3
24
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(166)
Caffeine 25 mg/ml 48 hrs, 4-day adult
76
Paraquat 5 mM 48 hrs, 4-day adult
120
Paraquat 10 mM 48 hrs, 4-day adult
99
Rotenone 2 μg 12 hrs, larvae L3
33
Rotenone 8 μg 12 hrs, larvae L3
36
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
93
cold shock, 4-day adult
66
heat shock, 4-day adult
73
Cadmium 50 mM 6 hrs, larvae L3
33
Cadmium 50 mM 12 hrs, larvae L3
45
Cadmium 50 mM 48 hrs, 4-day adult
69
Cadmium 100 mM 48 hrs, 4-day adult
165
Copper 0.5 mM 12 hrs, larvae L3
48
Copper 15 mM 48 hrs, 4-day adult
125
Zinc 5 mM 12 hrs, larvae L3
39
Zinc 4.5 mM 48 hrs, 4-day adult
56
Ethanol 2.5% 3 hrs, larvae L3
142
Ethanol 5% 3 hrs, larvae L3
26
Ethanol 10% 3 hrs, larvae L3
32
Caffeine 1.5 mg/ml 4 hrs, larvae L3
24
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
166
Caffeine 25 mg/ml 48 hrs, 4-day adult
76
Paraquat 5 mM 48 hrs, 4-day adult
120
Paraquat 10 mM 48 hrs, 4-day adult
99
Rotenone 2 μg 12 hrs, larvae L3
33
Rotenone 8 μg 12 hrs, larvae L3
36
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 2 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 2 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Disrupted in Transgenic Constructs & Insertions
Transgenic Constructs characterization construct
Insertions Gene Ontology: Function, Process
& Cellular Component ( 5 unique terms ) Terms Based on
Experimental Evidence ( 0 terms ) Terms Based on Predictions or
Assertions ( 5 terms ) Molecular Function Biological Process Cellular Component inferred from sequence or structural similarity with
UniProtKB:Q99417
(assigned by UniProtKB)
Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A comprehensive database of gene and protein interactions.
Orthologs
OrthoDB Orthologs (16)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
No orthologs identified
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
No orthologs identified
Orthologs in Drosophila Species
(EOG6HDTF6 )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG6PCB2M )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods
(EOG6NGF4W )
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 3 )Bloomington Harvard VDRC Genomic Clones ( 1 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 6 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for database merge of Source for merge of: CG17202 BcDNA:RH21090
Additional comments Source for merge of CG17202 BcDNA:RH21090 was a shared cDNA (date:030728).
Other Comments External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 2 )Reported As Symbol Synonym Name Synonym Secondary FlyBase
IDs References ( 16 )Research paper Johnson et al., 2010, PLoS Genet. 6(3): e1000872PPS, a Large Multidomain Protein, Functions with Sex-Lethal to Regulate Alternative Splicing in Drosophila. [FBrf0210202] Geng and MacDonald, 2007, Fly 1(5): 259--267Identification of genes that influence gurken expression. [FBrf0205043] Supplementary material Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Personal communication to FlyBase Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi CenterRNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] GOA Curators et al., 2007, Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity. [FBrf0212479] Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file)Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase.Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data.Exelixis CG deletion data. [FBrf0184335] Gene Disruption Project members, 2001-, (Computer file)(Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file)Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078] FlyBase analysis FlyBase Curators, 2010-, Gene Ontology (GO) annotation review.Gene Ontology (GO) annotation review. [FBrf0216433] FlyBase, 1996-, FlyBase inference based on genome sequence analysis.FlyBase inference based on genome sequence analysis. [FBrf0104946] Website Fisher et al., 2012, BDGP insitu homepageBDGP insitu homepage [FBrf0219073] Protein sequence record Swiss-Prot Project Members, 2002.3.1, UniProtKB: Q9VG76C-Myc binding protein homolog. [FBrf0151089]