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Gene Dmel\CG12360

General Information
Symbol	Dmel\CG12360	Species	D. melanogaster
Name		Annotation symbol	CG12360
Feature type	protein_coding_gene	FlyBase ID	FBgn0038111
Gene Model Status	Current	Stock availability	7 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	87D9-87D9	Sequence location	3R:8,852,747..8,856,372 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG12360 (FBgn0038111). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Pheromone shutdown, TraB. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: larval Malpighian tubules, larval/adult salivary gland, adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, larval/adult fat body, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1636280_s_at completely aligns to an exonic region of only a subset of 2 of the 3 FlyBase-annotated transcript isoforms of CG12360. Gene sequence location is 3R:8852747..8856372.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN46384 BKN20609 HFA14505
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 87D9-87D9   Limits computationally determined from genome sequence between P{PZ}CtBP03463 and P{lacW}B52s2249&P{lacW}flflL4179
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG12360 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG12360-RA FBtr0082717  NM_141996   2215   532 CG12360-RB FBtr0082718  NM_169493   2053   532 CG12360-RC FBtr0113229  NM_001104295   1310   333
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG12360-PA   FBpp0082185   58.8   532   6.05     NP_650253   AAF54893 CG12360-PB   FBpp0082186   58.8   532   6.05     NP_731765   AAN14341 CG12360-PC   FBpp0112141   38.9   333   6.36     NP_001097765   ABW08656
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Pheromone shutdown, TraB (IPR002816)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA392714   AA695806   AA803995   AE014297 AAF54893   AE014297 AAN14341   AE014297 ABW08656   AI530967   AI945083   AY070575 AAL48046   BF486027   BF486362   BF487308   BF490007   BF490140   BF492312   BF496504   BF497716   BF503851   BF505253   BG633967   BG635147   BI170566   BI173449   BI214935   BI230059   BI240840   BI354477   BI354500   BI367559   BI368201   BI368951   BI573251   BI573252   BI623508   BI632969   BT029708   CO192259   CO196476   CO262006   CO265462   CO270349   CO270872   CO271118   CO281050   CO287115   CO287188   CO291141   CO296991   CO303779   CO311407   CO319637   CO327798   CO339191   CO342705   CZ487524   CZ487525   EC059876   EC061375   EC069696   EC079889   EC081976   EC084585   EC201835   EC207500   EC212200   EC228679   EC245012   EC248241   EC255766   EC256685   EC257273   EL885976   EL885977
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VG01 A1A735
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0038111    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0038111 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0038111 expression level Developmental Stage   Expression Level embryo 00-02hr    2946 embryo 02-04hr    2520 embryo 04-06hr    2335 embryo 06-08hr    2280 embryo 08-10hr    2129 embryo 10-12hr    1838 embryo 12-14hr    1696 embryo 14-16hr    1449 embryo 16-18hr    1442 embryo 18-20hr    1084 embryo 20-22hr    768 embryo 22-24hr    775 larva L1    914 larva L2    1332 larva L3 12hr old    1054 larva L3 puffstage 1-2    1523 larva L3 puffstage 3-6    2066 larva L3 puffstage 7-9    2344 white prepupae new    2236 white prepupae 12hr    2280 white prepupae 24hr    2885 pupae 2d postWPP    3076 pupae 3d postWPP    2454 pupae 4d postWPP    1986 adult male 01day    3038 adult male 05day    4516 adult male 30day    3882 adult female 01day    1205 adult female 05day    1956 adult female 30day    1984 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2946) embryo 02-04hr  (2520) embryo 04-06hr  (2335) embryo 06-08hr  (2280) embryo 08-10hr  (2129) embryo 10-12hr  (1838) embryo 12-14hr  (1696) embryo 14-16hr  (1449) embryo 16-18hr  (1442) embryo 18-20hr  (1084) embryo 20-22hr  (768) embryo 22-24hr  (775) larva L1  (914) larva L2  (1332) larva L3 12hr old  (1054) larva L3 puffstage 1-2  (1523) larva L3 puffstage 3-6  (2066) larva L3 puffstage 7-9  (2344) white prepupae new  (2236) white prepupae 12hr  (2280) white prepupae 24hr  (2885) pupae 2d postWPP  (3076) pupae 3d postWPP  (2454) pupae 4d postWPP  (1986) adult male 01day  (3038) adult male 05day  (4516) adult male 30day  (3882) adult female 01day  (1205) adult female 05day  (1956) adult female 30day  (1984) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2946) embryo 02-04hr  (2520) embryo 04-06hr  (2335) embryo 06-08hr  (2280) embryo 08-10hr  (2129) embryo 10-12hr  (1838) embryo 12-14hr  (1696) embryo 14-16hr  1449 embryo 16-18hr  1442 embryo 18-20hr    1084 embryo 20-22hr    768 embryo 22-24hr    775 larva L1    914 larva L2    1332 larva L3 12hr old    1054 larva L3 puffstage 1-2  (1523) larva L3 puffstage 3-6  (2066) larva L3 puffstage 7-9  (2344) white prepupae new  (2236) white prepupae 12hr  (2280) white prepupae 24hr  (2885) pupae 2d postWPP  (3076) pupae 3d postWPP  (2454) pupae 4d postWPP  (1986) adult male 01day  (3038) adult male 05day  (4516) adult male 30day  (3882) adult female 01day    1205 adult female 05day  (1956) adult female 30day  (1984) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2946 embryo 02-04hr    2520 embryo 04-06hr    2335 embryo 06-08hr    2280 embryo 08-10hr    2129 embryo 10-12hr    1838 embryo 12-14hr    1696 embryo 14-16hr    1449 embryo 16-18hr    1442 embryo 18-20hr    1084 embryo 20-22hr    768 embryo 22-24hr    775 larva L1    914 larva L2    1332 larva L3 12hr old    1054 larva L3 puffstage 1-2    1523 larva L3 puffstage 3-6    2066 larva L3 puffstage 7-9    2344 white prepupae new    2236 white prepupae 12hr    2280 white prepupae 24hr    2885 pupae 2d postWPP    3076 pupae 3d postWPP    2454 pupae 4d postWPP    1986 adult male 01day    3038 adult male 05day    4516 adult male 30day    3882 adult female 01day    1205 adult female 05day    1956 adult female 30day    1984 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2946 embryo 02-04hr    2520 embryo 04-06hr    2335 embryo 06-08hr    2280 embryo 08-10hr    2129 embryo 10-12hr    1838 embryo 12-14hr    1696 embryo 14-16hr    1449 embryo 16-18hr    1442 embryo 18-20hr    1084 embryo 20-22hr    768 embryo 22-24hr    775 larva L1    914 larva L2    1332 larva L3 12hr old    1054 larva L3 puffstage 1-2    1523 larva L3 puffstage 3-6    2066 larva L3 puffstage 7-9    2344 white prepupae new    2236 white prepupae 12hr    2280 white prepupae 24hr    2885 pupae 2d postWPP    3076 pupae 3d postWPP    2454 pupae 4d postWPP    1986 adult male 01day    3038 adult male 05day    4516 adult male 30day    3882 adult female 01day    1205 adult female 05day    1956 adult female 30day    1984 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0038111 expression level Developmental Stage   Expression Level embryo 00-02hr    2946 embryo 02-04hr    2520 embryo 04-06hr    2335 embryo 06-08hr    2280 embryo 08-10hr    2129 embryo 10-12hr    1838 embryo 12-14hr    1696 embryo 14-16hr    1449 embryo 16-18hr    1442 embryo 18-20hr    1084 embryo 20-22hr    768 embryo 22-24hr    775 larva L1    914 larva L2    1332 larva L3 12hr old    1054 larva L3 puffstage 1-2    1523 larva L3 puffstage 3-6    2066 larva L3 puffstage 7-9    2344 white prepupae new    2236 white prepupae 12hr    2280 white prepupae 24hr    2885 pupae 2d postWPP    3076 pupae 3d postWPP    2454 pupae 4d postWPP    1986 adult male 01day    3038 adult male 05day    4516 adult male 30day    3882 adult female 01day    1205 adult female 05day    1956 adult female 30day    1984 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2946) embryo 02-04hr  (2520) embryo 04-06hr  (2335) embryo 06-08hr  (2280) embryo 08-10hr  (2129) embryo 10-12hr  (1838) embryo 12-14hr  (1696) embryo 14-16hr  (1449) embryo 16-18hr  (1442) embryo 18-20hr  (1084) embryo 20-22hr  (768) embryo 22-24hr  (775) larva L1  (914) larva L2  (1332) larva L3 12hr old  (1054) larva L3 puffstage 1-2  (1523) larva L3 puffstage 3-6  (2066) larva L3 puffstage 7-9  (2344) white prepupae new  (2236) white prepupae 12hr  (2280) white prepupae 24hr  (2885) pupae 2d postWPP  (3076) pupae 3d postWPP  (2454) pupae 4d postWPP  (1986) adult male 01day  (3038) adult male 05day  (4516) adult male 30day  (3882) adult female 01day  (1205) adult female 05day  (1956) adult female 30day  (1984) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2946) embryo 02-04hr  (2520) embryo 04-06hr  2335 embryo 06-08hr  2280 embryo 08-10hr  2129 embryo 10-12hr  1838 embryo 12-14hr  1696 embryo 14-16hr  1449 embryo 16-18hr  1442 embryo 18-20hr    1084 embryo 20-22hr    768 embryo 22-24hr    775 larva L1    914 larva L2    1332 larva L3 12hr old    1054 larva L3 puffstage 1-2  1523 larva L3 puffstage 3-6  2066 larva L3 puffstage 7-9  2344 white prepupae new  2236 white prepupae 12hr  2280 white prepupae 24hr  (2885) pupae 2d postWPP  (3076) pupae 3d postWPP  2454 pupae 4d postWPP  1986 adult male 01day  (3038) adult male 05day  (4516) adult male 30day  (3882) adult female 01day    1205 adult female 05day  1956 adult female 30day  1984 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2946 embryo 02-04hr    2520 embryo 04-06hr    2335 embryo 06-08hr    2280 embryo 08-10hr    2129 embryo 10-12hr    1838 embryo 12-14hr    1696 embryo 14-16hr    1449 embryo 16-18hr    1442 embryo 18-20hr    1084 embryo 20-22hr    768 embryo 22-24hr    775 larva L1    914 larva L2    1332 larva L3 12hr old    1054 larva L3 puffstage 1-2    1523 larva L3 puffstage 3-6    2066 larva L3 puffstage 7-9    2344 white prepupae new    2236 white prepupae 12hr    2280 white prepupae 24hr    2885 pupae 2d postWPP    3076 pupae 3d postWPP    2454 pupae 4d postWPP    1986 adult male 01day    3038 adult male 05day    4516 adult male 30day    3882 adult female 01day    1205 adult female 05day    1956 adult female 30day    1984 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2946 embryo 02-04hr    2520 embryo 04-06hr    2335 embryo 06-08hr    2280 embryo 08-10hr    2129 embryo 10-12hr    1838 embryo 12-14hr    1696 embryo 14-16hr    1449 embryo 16-18hr    1442 embryo 18-20hr    1084 embryo 20-22hr    768 embryo 22-24hr    775 larva L1    914 larva L2    1332 larva L3 12hr old    1054 larva L3 puffstage 1-2    1523 larva L3 puffstage 3-6    2066 larva L3 puffstage 7-9    2344 white prepupae new    2236 white prepupae 12hr    2280 white prepupae 24hr    2885 pupae 2d postWPP    3076 pupae 3d postWPP    2454 pupae 4d postWPP    1986 adult male 01day    3038 adult male 05day    4516 adult male 30day    3882 adult female 01day    1205 adult female 05day    1956 adult female 30day    1984 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0038111    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0038111 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: larval Malpighian tubules, larval/adult salivary gland, adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, larval/adult fat body, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0038111 expression level Tissue   Expression Level Larval Central Nervous System    173.575 Larval Midgut    203 Larval Hindgut    136.2 Larval Malpighian Tubules    659.4 Larval Fat Body    419.9 Larval Salivary Gland    666.6 Larval Trachea    126.075 Larval Carcass    105.15 Adult Head    121.2 Adult Eye    151.95 Adult Brain    204.8 Adult Thoracic-Abdominal Ganglion    120.9 Adult Crop    133.6 Adult Midgut    193.1 Adult Hindgut    105.6 Adult Malpighian Tubules    376.9 Adult Fat Body    121.5 Adult Salivary Gland    555.8 Adult Heart    104.375 Adult VirginFemale Spermatheca    64.8 Adult InseminatedFemale Spermatheca    103.8 Adult Ovary    355.2 Adult Testis    1148.6 Adult Male Accessory Gland    165.1 Adult Carcass    109.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    173.575 Larval Midgut    203 Larval Hindgut    136.2 Larval Malpighian Tubules  (659.4) Larval Fat Body    419.9 Larval Salivary Gland  (666.6) Larval Trachea    126.075 Larval Carcass    105.15 Adult Head    121.2 Adult Eye    151.95 Adult Brain    204.8 Adult Thoracic-Abdominal Ganglion    120.9 Adult Crop    133.6 Adult Midgut    193.1 Adult Hindgut    105.6 Adult Malpighian Tubules    376.9 Adult Fat Body    121.5 Adult Salivary Gland  (555.8) Adult Heart    104.375 Adult VirginFemale Spermatheca    64.8 Adult InseminatedFemale Spermatheca    103.8 Adult Ovary    355.2 Adult Testis  (1148.6) Adult Male Accessory Gland    165.1 Adult Carcass    109.2 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    173.575 Larval Midgut    203 Larval Hindgut    136.2 Larval Malpighian Tubules    659.4 Larval Fat Body    419.9 Larval Salivary Gland    666.6 Larval Trachea    126.075 Larval Carcass    105.15 Adult Head    121.2 Adult Eye    151.95 Adult Brain    204.8 Adult Thoracic-Abdominal Ganglion    120.9 Adult Crop    133.6 Adult Midgut    193.1 Adult Hindgut    105.6 Adult Malpighian Tubules    376.9 Adult Fat Body    121.5 Adult Salivary Gland    555.8 Adult Heart    104.375 Adult VirginFemale Spermatheca    64.8 Adult InseminatedFemale Spermatheca    103.8 Adult Ovary    355.2 Adult Testis  (1148.6) Adult Male Accessory Gland    165.1 Adult Carcass    109.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    173.575 Larval Midgut    203 Larval Hindgut    136.2 Larval Malpighian Tubules    659.4 Larval Fat Body    419.9 Larval Salivary Gland    666.6 Larval Trachea    126.075 Larval Carcass    105.15 Adult Head    121.2 Adult Eye    151.95 Adult Brain    204.8 Adult Thoracic-Abdominal Ganglion    120.9 Adult Crop    133.6 Adult Midgut    193.1 Adult Hindgut    105.6 Adult Malpighian Tubules    376.9 Adult Fat Body    121.5 Adult Salivary Gland    555.8 Adult Heart    104.375 Adult VirginFemale Spermatheca    64.8 Adult InseminatedFemale Spermatheca    103.8 Adult Ovary    355.2 Adult Testis    1148.6 Adult Male Accessory Gland    165.1 Adult Carcass    109.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0038111 expression level Tissue   Expression Level Larval Central Nervous System    173.575 Larval Midgut    203 Larval Hindgut    136.2 Larval Malpighian Tubules    659.4 Larval Fat Body    419.9 Larval Salivary Gland    666.6 Larval Trachea    126.075 Larval Carcass    105.15 Adult Head    121.2 Adult Eye    151.95 Adult Brain    204.8 Adult Thoracic-Abdominal Ganglion    120.9 Adult Crop    133.6 Adult Midgut    193.1 Adult Hindgut    105.6 Adult Malpighian Tubules    376.9 Adult Fat Body    121.5 Adult Salivary Gland    555.8 Adult Heart    104.375 Adult VirginFemale Spermatheca    64.8 Adult InseminatedFemale Spermatheca    103.8 Adult Ovary    355.2 Adult Testis    1148.6 Adult Male Accessory Gland    165.1 Adult Carcass    109.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    173.575 Larval Midgut    203 Larval Hindgut    136.2 Larval Malpighian Tubules  659.4 Larval Fat Body    419.9 Larval Salivary Gland  666.6 Larval Trachea    126.075 Larval Carcass    105.15 Adult Head    121.2 Adult Eye    151.95 Adult Brain    204.8 Adult Thoracic-Abdominal Ganglion    120.9 Adult Crop    133.6 Adult Midgut    193.1 Adult Hindgut    105.6 Adult Malpighian Tubules    376.9 Adult Fat Body    121.5 Adult Salivary Gland  555.8 Adult Heart    104.375 Adult VirginFemale Spermatheca    64.8 Adult InseminatedFemale Spermatheca    103.8 Adult Ovary    355.2 Adult Testis  (1148.6) Adult Male Accessory Gland    165.1 Adult Carcass    109.2 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    173.575 Larval Midgut    203 Larval Hindgut    136.2 Larval Malpighian Tubules    659.4 Larval Fat Body    419.9 Larval Salivary Gland    666.6 Larval Trachea    126.075 Larval Carcass    105.15 Adult Head    121.2 Adult Eye    151.95 Adult Brain    204.8 Adult Thoracic-Abdominal Ganglion    120.9 Adult Crop    133.6 Adult Midgut    193.1 Adult Hindgut    105.6 Adult Malpighian Tubules    376.9 Adult Fat Body    121.5 Adult Salivary Gland    555.8 Adult Heart    104.375 Adult VirginFemale Spermatheca    64.8 Adult InseminatedFemale Spermatheca    103.8 Adult Ovary    355.2 Adult Testis  1148.6 Adult Male Accessory Gland    165.1 Adult Carcass    109.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    173.575 Larval Midgut    203 Larval Hindgut    136.2 Larval Malpighian Tubules    659.4 Larval Fat Body    419.9 Larval Salivary Gland    666.6 Larval Trachea    126.075 Larval Carcass    105.15 Adult Head    121.2 Adult Eye    151.95 Adult Brain    204.8 Adult Thoracic-Abdominal Ganglion    120.9 Adult Crop    133.6 Adult Midgut    193.1 Adult Hindgut    105.6 Adult Malpighian Tubules    376.9 Adult Fat Body    121.5 Adult Salivary Gland    555.8 Adult Heart    104.375 Adult VirginFemale Spermatheca    64.8 Adult InseminatedFemale Spermatheca    103.8 Adult Ovary    355.2 Adult Testis    1148.6 Adult Male Accessory Gland    165.1 Adult Carcass    109.2 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    121.2   NA  Eye    151.95   NA  Brain    204.8   173.575  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    120.9   NA  Crop    133.6   203  Midgut    193.1   136.2  Hindgut    105.6   659.4  Malpighian Tubules    376.9   419.9  Fat Body    121.5   666.6  Salivary Gland    555.8   NA  Heart    104.375   126.075  Trachea    NA   NA  VirginFemale Spermatheca    64.8   NA  InseminatedFemale Spermatheca    103.8   NA  Ovary    355.2   NA  Testis    1148.6   NA  Male Accessory Gland    165.1   105.15  Carcass    109.2 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_21
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038111 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12360-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG12360 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG12360e03481 viable, with Scer\GAL4pnr-MD237 CG12360GD7582 Sterility Allele fertile CG12360e03481 Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of CG12360 Class Mutagen Stocks Known lesion CG12360e03481 piggyBac transposase 2 -- CG12360f04938 piggyBac transposase 1 -- CG12360MI01939 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG12360 Class Mutagen Stocks Known lesion CG12360GD7582 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG12360HMS01329 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel8157 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7582} NA P{TRiP.HMS01329} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions Mi{MIC}CG12360MI01939 NA P{PTT-GB}CB02135 NA PBac{RB}CG12360e03481 NA PBac{WH}CG12360f04938 NA insertion of mobile activating element P{GSV1}EP-650EP-650 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG12360 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 66691 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0038111 DroID - A comprehensive database of gene and protein interactions. • FBgn0038111 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41603
Orthologs
Genome-wide drosophilid orthologs	Dana\GF18088 Dere\GG17082 Dgri\GH19196 Dmoj\GI24230 Dper\GL23149 Dpse\GA27159 Dsec\GM25964 Dsim\GD20525 Dvir\GJ10803 Dwil\GK10854 Dyak\GE24471
Curated drosophilid orthologs
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL008613-PA Aedes aegypti (mosquito) AGAP004340-PA Anopheles gambiae (mosquito) XP_397164.3 Apis mellifera (honey bee) At1g05270.1 Arabidopsis thaliana (wall cress) 203438 Branchiostoma floridae (lancelet) XP_001891831.1 Brugia malayi (roundworm nematode) CN20302 Caenorhabditis brenneri (small nematode) CBP31498 Caenorhabditis briggsae (nematode) CE34010 Caenorhabditis elegans (worm) ENSCAFP00000000997 Canis familiaris (dog) ENSCINP00000012765 Ciona intestinalis (sea squirt) JA15363 Caenorhabditis japonica (nematode) CPIJ005378 Culex pipens (mosquito) ENSCPOP00000015515 Cavia porcellus (guinea pig) RP25369 Caenorhabditis remanei (nematode) 182788 Capitella spl (polychaete worm) DDB0187247 Dictyostelium discoideum (amoeba) 95443 Daphnia pulex (daphnia) ENSDARP00000015662 Danio rerio (zebra fish) ENSECAP00000019771 Equus caballus (horse) ENSGACP00000017788 Gymnopilus aculeatus (mushroom) ENSGALP00000014151 Gallus gallus (chicken) 66410 Hypsipyla robusta (cedar shoot borer) ENSP00000379173 Homo sapiens (human) ISCW013325-PA Ixodes scapularis (deer tick) 113686 Lottia gigantea (owl limpet) ENSMODP00000006797 Monodelphis domestica (gray opossum) ENSMMUP00000018524 Macaca mulatta (rhesus monkey) 51463 Nematostella vectensis (starlet anemone) XP_001604739.1 Nasonia vitripennis (wasp) PHUM009090-PA Pediculus humanus (human body louse) 99700 Physcomitrella patens (moss) ENSPPYP00000013359 Pongo pygmaeus (orangutan) 216753 Populus trichocarpa (black cottonwood) ENSRNOP00000039102 Rattus norvegicus (norway rat) Smp_050430 Schistosoma mansoni (trematode parasite) XP_001197364.1 Strongylocentrotus purpuratus (purple sea urchin) XP_969585.1 Tribolium castaneum (red flour beetle) ENSTNIP00000011196 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000011722 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000048193 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16648 NV16419 LH14308 ISCW013325 FBgn0241587 FBgn0212865 FBgn0198074 FBgn0191995 FBgn0180820 JGI_V11_95443 FBgn0160739 FBgn0146953 FBgn0126663 FBgn0109310 FBgn0095106 CPIJ005378 BGIBMGA000289 BGIBMGA000288 ACYPI48508 ACYPI005592 AGAP004340 AAEL008613 PHUM381560 GLEAN_16318
Stocks & Reagents
Stocks Listed in FlyBase ( 7 )
Bloomington	18161 w1118; PBac{RB}CG12360e03481 35955 y1 w*; Mi{MIC}CG12360MI01939 34341 y1 sc* v1; P{TRiP.HMS01329}attP2
Harvard	- PBac{RB}CG12360e03481 - PBac{WH}CG12360f04938
VDRC	v41487 w1118; P{GD7582}v41487 v41486 w1118; P{GD7582}v41486/CyO
Genomic Clones ( 1 )
	BACR17F05 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 66 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	IP17475 RE12073
Other clones	DPiM_RE12073
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT05068 AT07441 AT10443 AT11974 AT20156 AT20638 AT22068 AT26271 AT26434 AT29231 AT29966 AT31638 GM04512 GM12484 GM26964 GM27047 LD11819 RE16369 RE21089 RE27985 RE37775 RE53351 RE54128 RE55016 RH55787 SD01779 SD26879
Other clones	32836 37345 37409.1 66744 82196 103104 214339.44 214373.49 214449.45 bs08g08 CK01.17B.C8 CK01.64B.F10 CK01.82B.B8 CK01.98C.F8 CK01.116A.D4 CK01.133B.F11 EC33441 EK004808 EK064940 EK065153 EK076240 EK083605 EK098607 EK100905 EK102022 EK142727 EK155851 EK215626 EK224509 EK242735 EK279705 EP01041 EP08045 EP15354 IP17275 RH08951
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0038111 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41603
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_141996 NM_169493 NM_001104295 RefSeq (Proteins) • NP_650253 NP_731765 NP_001097765 DDBJ / EMBL / GenBank • AAF54893 AAL48046 AAN14341 ABW08656 AI530967 AI945083 AY070575 BI170566 CZ487524 CZ487525 Entrez Gene - A searchable database of RefSeq genes. • 41603 UniProtKB/TrEMBL • A1A735 Q9VG01
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Pheromone shutdown, TraB (IPR002816)
Linkouts
	BioGRID - A database of protein and genetic interactions • 66691 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0038111 DroID - A comprehensive database of gene and protein interactions. • FBgn0038111 DRSC - Results from RNAi screens. • FBgn0038111 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038111 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12360-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0038111 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41603 InParanoid A subset of ortholog calls from InParanoid. • AAEL008613-PA Aedes aegypti (mosquito) AGAP004340-PA Anopheles gambiae (mosquito) XP_397164.3 Apis mellifera (honey bee) At1g05270.1 Arabidopsis thaliana (wall cress) 203438 Branchiostoma floridae (lancelet) XP_001891831.1 Brugia malayi (roundworm nematode) CN20302 Caenorhabditis brenneri (small nematode) CBP31498 Caenorhabditis briggsae (nematode) CE34010 Caenorhabditis elegans (worm) ENSCAFP00000000997 Canis familiaris (dog) ENSCINP00000012765 Ciona intestinalis (sea squirt) JA15363 Caenorhabditis japonica (nematode) CPIJ005378 Culex pipens (mosquito) ENSCPOP00000015515 Cavia porcellus (guinea pig) RP25369 Caenorhabditis remanei (nematode) 182788 Capitella spl (polychaete worm) DDB0187247 Dictyostelium discoideum (amoeba) 95443 Daphnia pulex (daphnia) ENSDARP00000015662 Danio rerio (zebra fish) ENSECAP00000019771 Equus caballus (horse) ENSGACP00000017788 Gymnopilus aculeatus (mushroom) ENSGALP00000014151 Gallus gallus (chicken) 66410 Hypsipyla robusta (cedar shoot borer) ENSP00000379173 Homo sapiens (human) ISCW013325-PA Ixodes scapularis (deer tick) 113686 Lottia gigantea (owl limpet) ENSMODP00000006797 Monodelphis domestica (gray opossum) ENSMMUP00000018524 Macaca mulatta (rhesus monkey) 51463 Nematostella vectensis (starlet anemone) XP_001604739.1 Nasonia vitripennis (wasp) PHUM009090-PA Pediculus humanus (human body louse) 99700 Physcomitrella patens (moss) ENSPPYP00000013359 Pongo pygmaeus (orangutan) 216753 Populus trichocarpa (black cottonwood) ENSRNOP00000039102 Rattus norvegicus (norway rat) Smp_050430 Schistosoma mansoni (trematode parasite) XP_001197364.1 Strongylocentrotus purpuratus (purple sea urchin) XP_969585.1 Tribolium castaneum (red flour beetle) ENSTNIP00000011196 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000011722 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000048193 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41603 modMine - Data generated by the modENCODE project. • FBgn0038111 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16648 NV16419 LH14308 ISCW013325 FBgn0241587 FBgn0212865 FBgn0198074 FBgn0191995 FBgn0180820 JGI_V11_95443 FBgn0160739 FBgn0146953 FBgn0126663 FBgn0109310 FBgn0095106 CPIJ005378 BGIBMGA000289 BGIBMGA000288 ACYPI48508 ACYPI005592 AGAP004340 AAEL008613 PHUM381560 GLEAN_16318
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG12360 (Buszczak et al., 2007, Molnar et al., 2006, Gan et al., 2010, Ni et al., 2010.12.1)
Name Synonym
Secondary FlyBase IDs
References ( 18 )
Research paper	Gan et al., 2010, Cell Res. 20(7): 763--783 Dynamic regulation of alternative splicing and chromatin structure in Drosophila gonads revealed by RNA-seq. [FBrf0211191] Buszczak et al., 2007, Genetics 175(3): 1505--1531 The Carnegie protein trap library: A versatile tool for Drosophila developmental studies. [FBrf0200345] Molnar et al., 2006, Genetics 174(3): 1635--1659 A gain-of-function screen identifying genes required for vein formation in the Drosophila melanogaster wing. [FBrf0195387] Li and White, 2003, Dev. Cell 5(1): 59--72 Tissue-specific gene expression and ecdysone-regulated genomic networks in Drosophila. [FBrf0160735]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Bellen, 2011.5.24, set932.xml set932.xml [FBrf0213718] Ni et al., 2010.12.1, A genome-scale shRNA resource for transgenic RNAi in Drosophila. A genome-scale shRNA resource for transgenic RNAi in Drosophila. [FBrf0212437] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Oliver, 2001.8.16, File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). [FBrf0137492]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]