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Gene Dmel\CG8483

General Information
Symbol	Dmel\CG8483	Species	D. melanogaster
Name		Annotation symbol	CG8483
Feature type	protein_coding_gene	FlyBase ID	FBgn0038126
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	87E2-87E2	Sequence location	3R:9,034,470..9,040,187 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG8483 (FBgn0038126). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: Allergen V5/Tpx-1-related; Allergen V5/Tpx-1-related, conserved site; CAP domain; Ves allergen. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed at stages throughout the pupal period. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval trachea, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult crop, larval hindgut, adult salivary gland. Comments on Affy2 ProbeSet: ProbeSet 1639838_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG8483. Gene sequence location is 3R:9034470..9040187.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10	References FlyBase Curators, 2010-, Gene Ontology (GO) annotation review.
FB2012_01	Sequence features HFA16430 BKN21606
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 87E2-87E2   Limits computationally determined from genome sequence between P{PZ}CtBP03463 and P{lacW}B52s2249&P{lacW}flflL4179
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG8483 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG8483-RA FBtr0082782  NM_142007   1875   392
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG8483-PA   FBpp0082250   43.6   392   8.59     NP_650264   AAF54913
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Allergen V5/Tpx-1-related (IPR001283) Ves allergen (IPR002413) Allergen V5/Tpx-1-related, conserved site (IPR018244) CAP domain (IPR014044)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF54913   AI294220   AI297569   AI404083   AI519425   AW943449   AY051901 AAK93325   CO280796   EC213411   ES695714   GH942909   GH961831   GH979050   GH982781
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VFY2
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
expression microarray Stage Tissue/Position (including subcellular localization) Reference adult stage   eye   (Xu et al., 2004)
Additional Descriptive Data
	Eye-enriched transcripts determined by ratio of expression level in wild-type heads. versus expression level in so heads. (Xu et al., 2004)
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0038126    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0038126 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed at stages throughout the pupal period. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0038126 expression level Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    23 embryo 04-06hr    36 embryo 06-08hr    157 embryo 08-10hr    291 embryo 10-12hr    1262 embryo 12-14hr    1107 embryo 14-16hr    1259 embryo 16-18hr    300 embryo 18-20hr    567 embryo 20-22hr    690 embryo 22-24hr    819 larva L1    2167 larva L2    2441 larva L3 12hr old    2523 larva L3 puffstage 1-2    418 larva L3 puffstage 3-6    643 larva L3 puffstage 7-9    2954 white prepupae new    4083 white prepupae 12hr    18168 white prepupae 24hr    837 pupae 2d postWPP    1626 pupae 3d postWPP    849 pupae 4d postWPP    44957 adult male 01day    736 adult male 05day    149 adult male 30day    86 adult female 01day    745 adult female 05day    37 adult female 30day    40 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    23 embryo 04-06hr    36 embryo 06-08hr  (157) embryo 08-10hr  (291) embryo 10-12hr  (1262) embryo 12-14hr  (1107) embryo 14-16hr  (1259) embryo 16-18hr  (300) embryo 18-20hr  (567) embryo 20-22hr  (690) embryo 22-24hr  (819) larva L1  (2167) larva L2  (2441) larva L3 12hr old  (2523) larva L3 puffstage 1-2  (418) larva L3 puffstage 3-6  (643) larva L3 puffstage 7-9  (2954) white prepupae new  (4083) white prepupae 12hr  (18168) white prepupae 24hr  (837) pupae 2d postWPP  (1626) pupae 3d postWPP  (849) pupae 4d postWPP  (44957) adult male 01day  (736) adult male 05day  (149) adult male 30day    86 adult female 01day  (745) adult female 05day    37 adult female 30day    40 Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    23 embryo 04-06hr    36 embryo 06-08hr    157 embryo 08-10hr    291 embryo 10-12hr    1262 embryo 12-14hr    1107 embryo 14-16hr    1259 embryo 16-18hr    300 embryo 18-20hr    567 embryo 20-22hr    690 embryo 22-24hr    819 larva L1  (2167) larva L2  (2441) larva L3 12hr old  (2523) larva L3 puffstage 1-2    418 larva L3 puffstage 3-6    643 larva L3 puffstage 7-9  (2954) white prepupae new  (4083) white prepupae 12hr  (18168) white prepupae 24hr    837 pupae 2d postWPP  (1626) pupae 3d postWPP    849 pupae 4d postWPP  (44957) adult male 01day    736 adult male 05day    149 adult male 30day    86 adult female 01day    745 adult female 05day    37 adult female 30day    40 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    23 embryo 04-06hr    36 embryo 06-08hr    157 embryo 08-10hr    291 embryo 10-12hr    1262 embryo 12-14hr    1107 embryo 14-16hr    1259 embryo 16-18hr    300 embryo 18-20hr    567 embryo 20-22hr    690 embryo 22-24hr    819 larva L1    2167 larva L2    2441 larva L3 12hr old    2523 larva L3 puffstage 1-2    418 larva L3 puffstage 3-6    643 larva L3 puffstage 7-9    2954 white prepupae new    4083 white prepupae 12hr  (18168) white prepupae 24hr    837 pupae 2d postWPP    1626 pupae 3d postWPP    849 pupae 4d postWPP  (44957) adult male 01day    736 adult male 05day    149 adult male 30day    86 adult female 01day    745 adult female 05day    37 adult female 30day    40 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    23 embryo 04-06hr    36 embryo 06-08hr    157 embryo 08-10hr    291 embryo 10-12hr    1262 embryo 12-14hr    1107 embryo 14-16hr    1259 embryo 16-18hr    300 embryo 18-20hr    567 embryo 20-22hr    690 embryo 22-24hr    819 larva L1    2167 larva L2    2441 larva L3 12hr old    2523 larva L3 puffstage 1-2    418 larva L3 puffstage 3-6    643 larva L3 puffstage 7-9    2954 white prepupae new    4083 white prepupae 12hr    18168 white prepupae 24hr    837 pupae 2d postWPP    1626 pupae 3d postWPP    849 pupae 4d postWPP    44957 adult male 01day    736 adult male 05day    149 adult male 30day    86 adult female 01day    745 adult female 05day    37 adult female 30day    40 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0038126 expression level Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    23 embryo 04-06hr    36 embryo 06-08hr    157 embryo 08-10hr    291 embryo 10-12hr    1262 embryo 12-14hr    1107 embryo 14-16hr    1259 embryo 16-18hr    300 embryo 18-20hr    567 embryo 20-22hr    690 embryo 22-24hr    819 larva L1    2167 larva L2    2441 larva L3 12hr old    2523 larva L3 puffstage 1-2    418 larva L3 puffstage 3-6    643 larva L3 puffstage 7-9    2954 white prepupae new    4083 white prepupae 12hr    18168 white prepupae 24hr    837 pupae 2d postWPP    1626 pupae 3d postWPP    849 pupae 4d postWPP    44957 adult male 01day    736 adult male 05day    149 adult male 30day    86 adult female 01day    745 adult female 05day    37 adult female 30day    40 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    23 embryo 04-06hr    36 embryo 06-08hr  (157) embryo 08-10hr  (291) embryo 10-12hr  (1262) embryo 12-14hr  (1107) embryo 14-16hr  (1259) embryo 16-18hr  (300) embryo 18-20hr  (567) embryo 20-22hr  (690) embryo 22-24hr  (819) larva L1  (2167) larva L2  (2441) larva L3 12hr old  (2523) larva L3 puffstage 1-2  (418) larva L3 puffstage 3-6  (643) larva L3 puffstage 7-9  (2954) white prepupae new  (4083) white prepupae 12hr  (18168) white prepupae 24hr  (837) pupae 2d postWPP  (1626) pupae 3d postWPP  (849) pupae 4d postWPP  (44957) adult male 01day  (736) adult male 05day  (149) adult male 30day    86 adult female 01day  (745) adult female 05day    37 adult female 30day    40 Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    23 embryo 04-06hr    36 embryo 06-08hr    157 embryo 08-10hr    291 embryo 10-12hr    1262 embryo 12-14hr    1107 embryo 14-16hr    1259 embryo 16-18hr    300 embryo 18-20hr    567 embryo 20-22hr    690 embryo 22-24hr    819 larva L1  2167 larva L2  2441 larva L3 12hr old  (2523) larva L3 puffstage 1-2    418 larva L3 puffstage 3-6    643 larva L3 puffstage 7-9  (2954) white prepupae new  (4083) white prepupae 12hr  (18168) white prepupae 24hr    837 pupae 2d postWPP  1626 pupae 3d postWPP    849 pupae 4d postWPP  (44957) adult male 01day    736 adult male 05day    149 adult male 30day    86 adult female 01day    745 adult female 05day    37 adult female 30day    40 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    23 embryo 04-06hr    36 embryo 06-08hr    157 embryo 08-10hr    291 embryo 10-12hr    1262 embryo 12-14hr    1107 embryo 14-16hr    1259 embryo 16-18hr    300 embryo 18-20hr    567 embryo 20-22hr    690 embryo 22-24hr    819 larva L1    2167 larva L2    2441 larva L3 12hr old    2523 larva L3 puffstage 1-2    418 larva L3 puffstage 3-6    643 larva L3 puffstage 7-9    2954 white prepupae new    4083 white prepupae 12hr  18168 white prepupae 24hr    837 pupae 2d postWPP    1626 pupae 3d postWPP    849 pupae 4d postWPP  (44957) adult male 01day    736 adult male 05day    149 adult male 30day    86 adult female 01day    745 adult female 05day    37 adult female 30day    40 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    23 embryo 04-06hr    36 embryo 06-08hr    157 embryo 08-10hr    291 embryo 10-12hr    1262 embryo 12-14hr    1107 embryo 14-16hr    1259 embryo 16-18hr    300 embryo 18-20hr    567 embryo 20-22hr    690 embryo 22-24hr    819 larva L1    2167 larva L2    2441 larva L3 12hr old    2523 larva L3 puffstage 1-2    418 larva L3 puffstage 3-6    643 larva L3 puffstage 7-9    2954 white prepupae new    4083 white prepupae 12hr    18168 white prepupae 24hr    837 pupae 2d postWPP    1626 pupae 3d postWPP    849 pupae 4d postWPP    44957 adult male 01day    736 adult male 05day    149 adult male 30day    86 adult female 01day    745 adult female 05day    37 adult female 30day    40 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0038126    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0038126 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval trachea, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult crop, larval hindgut, adult salivary gland. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0038126 expression level Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut    37.4 Larval Hindgut    212.3 Larval Malpighian Tubules    3.1 Larval Fat Body    4.5 Larval Salivary Gland no informative data Larval Trachea    1152.35 Larval Carcass    544.85 Adult Head no informative data Adult Eye no informative data Adult Brain    8.2 Adult Thoracic-Abdominal Ganglion    7.3 Adult Crop    252 Adult Midgut    27 Adult Hindgut    34.4 Adult Malpighian Tubules    6.5 Adult Fat Body no informative data Adult Salivary Gland    278.6 Adult Heart    4.85 Adult VirginFemale Spermatheca    9.2 Adult InseminatedFemale Spermatheca    5.3 Adult Ovary    1.2 Adult Testis    3 Adult Male Accessory Gland    1.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut    37.4 Larval Hindgut    212.3 Larval Malpighian Tubules    3.1 Larval Fat Body    4.5 Larval Salivary Gland no informative data Larval Trachea  (1152.35) Larval Carcass  (544.85) Adult Head no informative data Adult Eye no informative data Adult Brain    8.2 Adult Thoracic-Abdominal Ganglion    7.3 Adult Crop    252 Adult Midgut    27 Adult Hindgut    34.4 Adult Malpighian Tubules    6.5 Adult Fat Body no informative data Adult Salivary Gland    278.6 Adult Heart    4.85 Adult VirginFemale Spermatheca    9.2 Adult InseminatedFemale Spermatheca    5.3 Adult Ovary    1.2 Adult Testis    3 Adult Male Accessory Gland    1.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut    37.4 Larval Hindgut    212.3 Larval Malpighian Tubules    3.1 Larval Fat Body    4.5 Larval Salivary Gland no informative data Larval Trachea  (1152.35) Larval Carcass    544.85 Adult Head no informative data Adult Eye no informative data Adult Brain    8.2 Adult Thoracic-Abdominal Ganglion    7.3 Adult Crop    252 Adult Midgut    27 Adult Hindgut    34.4 Adult Malpighian Tubules    6.5 Adult Fat Body no informative data Adult Salivary Gland    278.6 Adult Heart    4.85 Adult VirginFemale Spermatheca    9.2 Adult InseminatedFemale Spermatheca    5.3 Adult Ovary    1.2 Adult Testis    3 Adult Male Accessory Gland    1.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut    37.4 Larval Hindgut    212.3 Larval Malpighian Tubules    3.1 Larval Fat Body    4.5 Larval Salivary Gland no informative data Larval Trachea    1152.35 Larval Carcass    544.85 Adult Head no informative data Adult Eye no informative data Adult Brain    8.2 Adult Thoracic-Abdominal Ganglion    7.3 Adult Crop    252 Adult Midgut    27 Adult Hindgut    34.4 Adult Malpighian Tubules    6.5 Adult Fat Body no informative data Adult Salivary Gland    278.6 Adult Heart    4.85 Adult VirginFemale Spermatheca    9.2 Adult InseminatedFemale Spermatheca    5.3 Adult Ovary    1.2 Adult Testis    3 Adult Male Accessory Gland    1.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0038126 expression level Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut    37.4 Larval Hindgut    212.3 Larval Malpighian Tubules    3.1 Larval Fat Body    4.5 Larval Salivary Gland no informative data Larval Trachea    1152.35 Larval Carcass    544.85 Adult Head no informative data Adult Eye no informative data Adult Brain    8.2 Adult Thoracic-Abdominal Ganglion    7.3 Adult Crop    252 Adult Midgut    27 Adult Hindgut    34.4 Adult Malpighian Tubules    6.5 Adult Fat Body no informative data Adult Salivary Gland    278.6 Adult Heart    4.85 Adult VirginFemale Spermatheca    9.2 Adult InseminatedFemale Spermatheca    5.3 Adult Ovary    1.2 Adult Testis    3 Adult Male Accessory Gland    1.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut    37.4 Larval Hindgut    212.3 Larval Malpighian Tubules    3.1 Larval Fat Body    4.5 Larval Salivary Gland no informative data Larval Trachea  (1152.35) Larval Carcass  544.85 Adult Head no informative data Adult Eye no informative data Adult Brain    8.2 Adult Thoracic-Abdominal Ganglion    7.3 Adult Crop    252 Adult Midgut    27 Adult Hindgut    34.4 Adult Malpighian Tubules    6.5 Adult Fat Body no informative data Adult Salivary Gland    278.6 Adult Heart    4.85 Adult VirginFemale Spermatheca    9.2 Adult InseminatedFemale Spermatheca    5.3 Adult Ovary    1.2 Adult Testis    3 Adult Male Accessory Gland    1.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut    37.4 Larval Hindgut    212.3 Larval Malpighian Tubules    3.1 Larval Fat Body    4.5 Larval Salivary Gland no informative data Larval Trachea  1152.35 Larval Carcass    544.85 Adult Head no informative data Adult Eye no informative data Adult Brain    8.2 Adult Thoracic-Abdominal Ganglion    7.3 Adult Crop    252 Adult Midgut    27 Adult Hindgut    34.4 Adult Malpighian Tubules    6.5 Adult Fat Body no informative data Adult Salivary Gland    278.6 Adult Heart    4.85 Adult VirginFemale Spermatheca    9.2 Adult InseminatedFemale Spermatheca    5.3 Adult Ovary    1.2 Adult Testis    3 Adult Male Accessory Gland    1.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut    37.4 Larval Hindgut    212.3 Larval Malpighian Tubules    3.1 Larval Fat Body    4.5 Larval Salivary Gland no informative data Larval Trachea    1152.35 Larval Carcass    544.85 Adult Head no informative data Adult Eye no informative data Adult Brain    8.2 Adult Thoracic-Abdominal Ganglion    7.3 Adult Crop    252 Adult Midgut    27 Adult Hindgut    34.4 Adult Malpighian Tubules    6.5 Adult Fat Body no informative data Adult Salivary Gland    278.6 Adult Heart    4.85 Adult VirginFemale Spermatheca    9.2 Adult InseminatedFemale Spermatheca    5.3 Adult Ovary    1.2 Adult Testis    3 Adult Male Accessory Gland    1.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland no informative data Larval Trachea     Larval Carcass     Adult Head no informative data Adult Eye no informative data Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body no informative data Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    no informative data   NA  Eye    no informative data   NA  Brain    8.2   no informative data  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    7.3   NA  Crop    252   37.4  Midgut    27   212.3  Hindgut    34.4   3.1  Malpighian Tubules    6.5   4.5  Fat Body    no informative data   no informative data  Salivary Gland    278.6   NA  Heart    4.85   1152.35  Trachea    NA   NA  VirginFemale Spermatheca    9.2   NA  InseminatedFemale Spermatheca    5.3   NA  Ovary    1.2   NA  Testis    3   NA  Male Accessory Gland    1.6   544.85  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_25
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038126 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8483-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG8483 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pharate adult stage, with Scer\GAL4αTub84B.PL CG8483Scer\UAS.cJa lethal | pupal stage, with Scer\GAL4αTub84B.PL CG8483Scer\UAS.cJa semi-lethal | pupal stage, with Scer\GAL4pnr-MD237 CG8483GD5593 Other Phenotypes Allele body color defective, with Scer\GAL4pnr-MD237 CG8483GD5593 visible, with Scer\GAL4pnr-MD237 CG8483GD5593 Phenotype manifest in Allele chaeta | supernumerary, with Scer\GAL4pnr-MD237 CG8483GD5593 mesothoracic tergum, with Scer\GAL4pnr-MD237 CG8483GD5593
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG8483 Class Mutagen Stocks Known lesion CG8483MB07625 1 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG8483 Class Mutagen Stocks Known lesion CG8483GD5593 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG8483KK101555 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG8483dsRNA.Scer\UAS in vitro construct - regulatory fusion in vitro construct - RNAi 0 Yes CG8483Scer\UAS.cJa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6167 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD5593} NA P{KK101555} NA P{UAS-CG8483.J} NA P{UAS-CG8483.RNAi} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap binary system Mi{ET1}CG8483MB07625 No
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
	There is no information supporting a biological process or molecular function term for this gene. (Based on a review of available data on: 2011-08-18)
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
extracellular region inferred from electronic annotation with InterPro:IPR018244 (FlyBase Curators et al., 2004-) inferred from sequence model (Kovalick and Griffin, 2005)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG8483 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 66707 DroID - A comprehensive database of gene and protein interactions. • FBgn0038126 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41623
Orthologs
Genome-wide drosophilid orthologs	Dana\GF17401 Dere\GG17074 Dgri\GH19187 Dmoj\GI24221 Dper\GL23137 Dpse\GA21107 Dsec\GM25958 Dsim\GD20518 Dvir\GJ10792 Dwil\GK22774 Dyak\GE24462
Curated drosophilid orthologs	Dpse\GA21107
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL012136-PA Aedes aegypti (mosquito) XP_001946213.1 Acyrthosiphon pisum (pea aphid) XP_001895158.1 Brugia malayi (roundworm nematode) BGIBMGA012521-PA Bombyx mori (silk worm) ENSBTAP00000002703 Bos taurus (bovine) CN02748 Caenorhabditis brenneri (small nematode) CN05666 Caenorhabditis brenneri (small nematode) CBP28923 Caenorhabditis briggsae (nematode) CE01953 Caenorhabditis elegans (worm) ENSCINP00000009221 Ciona intestinalis (sea squirt) JA07423 Caenorhabditis japonica (nematode) JA17718 Caenorhabditis japonica (nematode) cgd5_2020 Cryptosporidium parvum (protozoan parasite) ENSCPOP00000009992 Cavia porcellus (guinea pig) RP00202 Caenorhabditis remanei (nematode) ENSCSAVP00000003463 Ciona savignyi (sedentary tunicate) 196237 Capitella spl (polychaete worm) 221885 Daphnia pulex (daphnia) ENSDARP00000022523 Danio rerio (zebra fish) ENSECAP00000017781 Equus caballus (horse) ENSGACP00000025712 Gymnopilus aculeatus (mushroom) ENSGALP00000026867 Gallus gallus (chicken) ISCW018564-PA Ixodes scapularis (deer tick) ENSMODP00000023511 Monodelphis domestica (gray opossum) ENSMUSP00000104809 Mus musculus (house mouse) XP_001605587.1 Nasonia vitripennis (wasp) ENSORLP00000020674 Oryzias latipes (japanese killifish) PP06433 Pristionchus pacificus (nematode) 73685 Phytophthora ramorum (sudden oak death pathogen) ENSPTRP00000014163 Pan troglodytes (chimpanzee) ENSRNOP00000000632 Rattus norvegicus (norway rat) Smp_159290 Schistosoma mansoni (trematode parasite) XP_001175890.1 Strongylocentrotus purpuratus (purple sea urchin) XP_001195938.1 Strongylocentrotus purpuratus (purple sea urchin) XP_971010.1 Tribolium castaneum (red flour beetle) ENSXETP00000024375 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV12499 LH22257 LH22255 ISCW018564 FBgn0241578 FBgn0224746 FBgn0198064 FBgn0191988 FBgn0180814 JGI_V11_221885 FBgn0081095 FBgn0160727 FBgn0146944 FBgn0126654 FBgn0109302 FBgn0094419 CPIJ000661 BGIBMGA012521 GB17780 AGAP003354 AAEL012136 AAEL011802 PB22781 GLEAN_00982
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	26081 w1118; Mi{ET1}CG8483MB07625
VDRC	v108588 P{KK101555}VIE-260B v41263 w1118 P{GD5593}v41263 v41264 w1118; P{GD5593}v41264
Genomic Clones ( 2 )
	BACR05K08 BACR48D15 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 10 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD39025
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH23674 LP07541 LP11896
Other clones	98355 EK154904 RP004217197 RP004253774 RP004254011 RP004531943
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0038126 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41623
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_142007 RefSeq (Proteins) • NP_650264 DDBJ / EMBL / GenBank • AAF54913 AAK93325 AI519425 AW943449 AY051901 Entrez Gene - A searchable database of RefSeq genes. • 41623 UniProtKB/TrEMBL • Q9VFY2
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Allergen V5/Tpx-1-related (IPR001283) Ves allergen (IPR002413) Allergen V5/Tpx-1-related, conserved site (IPR018244) CAP domain (IPR014044)
Linkouts
	BioGRID - A database of protein and genetic interactions • 66707 DroID - A comprehensive database of gene and protein interactions. • FBgn0038126 DRSC - Results from RNAi screens. • FBgn0038126 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038126 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8483-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0038126 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41623 InParanoid A subset of ortholog calls from InParanoid. • AAEL012136-PA Aedes aegypti (mosquito) XP_001946213.1 Acyrthosiphon pisum (pea aphid) XP_001895158.1 Brugia malayi (roundworm nematode) BGIBMGA012521-PA Bombyx mori (silk worm) ENSBTAP00000002703 Bos taurus (bovine) CN02748 Caenorhabditis brenneri (small nematode) CN05666 Caenorhabditis brenneri (small nematode) CBP28923 Caenorhabditis briggsae (nematode) CE01953 Caenorhabditis elegans (worm) ENSCINP00000009221 Ciona intestinalis (sea squirt) JA07423 Caenorhabditis japonica (nematode) JA17718 Caenorhabditis japonica (nematode) cgd5_2020 Cryptosporidium parvum (protozoan parasite) ENSCPOP00000009992 Cavia porcellus (guinea pig) RP00202 Caenorhabditis remanei (nematode) ENSCSAVP00000003463 Ciona savignyi (sedentary tunicate) 196237 Capitella spl (polychaete worm) 221885 Daphnia pulex (daphnia) ENSDARP00000022523 Danio rerio (zebra fish) ENSECAP00000017781 Equus caballus (horse) ENSGACP00000025712 Gymnopilus aculeatus (mushroom) ENSGALP00000026867 Gallus gallus (chicken) ISCW018564-PA Ixodes scapularis (deer tick) ENSMODP00000023511 Monodelphis domestica (gray opossum) ENSMUSP00000104809 Mus musculus (house mouse) XP_001605587.1 Nasonia vitripennis (wasp) ENSORLP00000020674 Oryzias latipes (japanese killifish) PP06433 Pristionchus pacificus (nematode) 73685 Phytophthora ramorum (sudden oak death pathogen) ENSPTRP00000014163 Pan troglodytes (chimpanzee) ENSRNOP00000000632 Rattus norvegicus (norway rat) Smp_159290 Schistosoma mansoni (trematode parasite) XP_001175890.1 Strongylocentrotus purpuratus (purple sea urchin) XP_001195938.1 Strongylocentrotus purpuratus (purple sea urchin) XP_971010.1 Tribolium castaneum (red flour beetle) ENSXETP00000024375 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41623 modMine - Data generated by the modENCODE project. • FBgn0038126 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV12499 LH22257 LH22255 ISCW018564 FBgn0241578 FBgn0224746 FBgn0198064 FBgn0191988 FBgn0180814 JGI_V11_221885 FBgn0081095 FBgn0160727 FBgn0146944 FBgn0126654 FBgn0109302 FBgn0094419 CPIJ000661 BGIBMGA012521 GB17780 AGAP003354 AAEL012136 AAEL011802 PB22781 GLEAN_00982
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG8483 (Kovalick and Griffin, 2005, Jacobsen et al., 2006, Keleman et al., 2009.8.5, Firth and Baker, 2007, Beckstead et al., 2005)
Name Synonym
Secondary FlyBase IDs
References ( 20 )
Research paper	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Firth and Baker, 2007, Dev. Biol. 307(2): 521--538 Spitz from the retina regulates genes transcribed in the second mitotic wave, peripodial epithelium, glia and plasmatocytes of the Drosophila eye imaginal disc. [FBrf0201413] Jacobsen et al., 2006, Genetics 174(4): 1973--1982 Functional analysis of genes differentially expressed in the Drosophila wing disc: role of transcripts enriched in the wing region. [FBrf0194659] Beckstead et al., 2005, GenomeBiol. 6(12): The genomic response to 20-hydroxyecdysone at the onset of Drosophila metamorphosis. [FBrf0190800] Kovalick and Griffin, 2005, Insect Biochem. Molec. Biol. 35(8): 825--835 Characterization of the SCP/TAPS gene family in Drosophila melanogaster. [FBrf0187745] Arbeitman et al., 2004, Development 131(9): 2007--2021 A genomic analysis of Drosophila somatic sexual differentiation and its regulation. [FBrf0174573] Xu et al., 2004, EMBO J. 23(4): 811--822 A lysosomal tetraspanin associated with retinal degeneration identified via a genome-wide screen. [FBrf0174603] Butler et al., 2003, Development 130(4): 659--670 Discovery of genes with highly restricted expression patterns in the Drosophila wing disc using DNA oligonucleotide microarrays. [FBrf0155718]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Bellen, 2008.11.7, set816.xml set816.xml [FBrf0206132] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase Curators, 2010-, Gene Ontology (GO) annotation review. Gene Ontology (GO) annotation review. [FBrf0216433] FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]