General Information Symbol Dmel\ CG12207Species D. melanogaster Name Annotation symbol CG12207 Feature type protein_coding_gene FlyBase ID FBgn0038220 Gene Model Status Current Stock availability 5 publicly
available Genomic Location Chromosome (arm) 3R Recombination map Cytogenetic map 88B1-88B3 Sequence location 3R:10,114,794..10,127,998 [+]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information This gene is referred to in FlyBase by the symbol
Dmel\CG12207 (FBgn0038220). It is a protein_coding_gene from
Drosophila melanogaster . Its
molecular function is unknown. An electronic pipeline based on InterPro domains suggests that it is involved in the
biological process : cell wall macromolecule catabolic process.
9 alleles are reported . No phenotypic data is available. It has
6 annotated transcripts and
6 annotated polypeptides .
Protein features are: Peptidoglycan-binding Lysin subgroup; Peptidoglycan-binding lysin domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, larval hindgut, larval/adult Malpighian tubules. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult hindgut, larval fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1628761_s_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of CG12207. Gene sequence location is
3R:10114794..10127998 .
User Contributed Data
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FB2013_03
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.41
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: maternally deposited
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
173.325
Larval Midgut
999.1
Larval Hindgut
647.7
Larval Malpighian Tubules
703.6
Larval Fat Body
254.6
Larval Salivary Gland
183.9
Larval Trachea
230.4
Larval Carcass
221.4
Adult Head
259.1
Adult Eye
316.225
Adult Brain
341.4
Adult Thoracic-Abdominal Ganglion
242.2
Adult Crop
232.8
Adult Midgut
697.8
Adult Hindgut
327.1
Adult Malpighian Tubules
1297.2
Adult Fat Body
90.7
Adult Salivary Gland
493.7
Adult Heart
92.125
Adult VirginFemale Spermatheca
100.3
Adult InseminatedFemale Spermatheca
97.4
Adult Ovary
407
Adult Testis
136.1
Adult Male Accessory Gland
149.1
Adult Carcass
242
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
173.325
Larval Midgut
(999.1)
Larval Hindgut
(647.7)
Larval Malpighian Tubules
(703.6)
Larval Fat Body
254.6
Larval Salivary Gland
183.9
Larval Trachea
230.4
Larval Carcass
221.4
Adult Head
259.1
Adult Eye
316.225
Adult Brain
341.4
Adult Thoracic-Abdominal Ganglion
242.2
Adult Crop
232.8
Adult Midgut
(697.8)
Adult Hindgut
327.1
Adult Malpighian Tubules
(1297.2)
Adult Fat Body
90.7
Adult Salivary Gland
493.7
Adult Heart
92.125
Adult VirginFemale Spermatheca
100.3
Adult InseminatedFemale Spermatheca
97.4
Adult Ovary
407
Adult Testis
136.1
Adult Male Accessory Gland
149.1
Adult Carcass
242
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
173.325
Larval Midgut
999.1
Larval Hindgut
647.7
Larval Malpighian Tubules
703.6
Larval Fat Body
254.6
Larval Salivary Gland
183.9
Larval Trachea
230.4
Larval Carcass
221.4
Adult Head
259.1
Adult Eye
316.225
Adult Brain
341.4
Adult Thoracic-Abdominal Ganglion
242.2
Adult Crop
232.8
Adult Midgut
697.8
Adult Hindgut
327.1
Adult Malpighian Tubules
(1297.2)
Adult Fat Body
90.7
Adult Salivary Gland
493.7
Adult Heart
92.125
Adult VirginFemale Spermatheca
100.3
Adult InseminatedFemale Spermatheca
97.4
Adult Ovary
407
Adult Testis
136.1
Adult Male Accessory Gland
149.1
Adult Carcass
242
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
173.325
Larval Midgut
999.1
Larval Hindgut
647.7
Larval Malpighian Tubules
703.6
Larval Fat Body
254.6
Larval Salivary Gland
183.9
Larval Trachea
230.4
Larval Carcass
221.4
Adult Head
259.1
Adult Eye
316.225
Adult Brain
341.4
Adult Thoracic-Abdominal Ganglion
242.2
Adult Crop
232.8
Adult Midgut
697.8
Adult Hindgut
327.1
Adult Malpighian Tubules
1297.2
Adult Fat Body
90.7
Adult Salivary Gland
493.7
Adult Heart
92.125
Adult VirginFemale Spermatheca
100.3
Adult InseminatedFemale Spermatheca
97.4
Adult Ovary
407
Adult Testis
136.1
Adult Male Accessory Gland
149.1
Adult Carcass
242
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
173.325
Larval Midgut
999.1
Larval Hindgut
647.7
Larval Malpighian Tubules
703.6
Larval Fat Body
254.6
Larval Salivary Gland
183.9
Larval Trachea
230.4
Larval Carcass
221.4
Adult Head
259.1
Adult Eye
316.225
Adult Brain
341.4
Adult Thoracic-Abdominal Ganglion
242.2
Adult Crop
232.8
Adult Midgut
697.8
Adult Hindgut
327.1
Adult Malpighian Tubules
1297.2
Adult Fat Body
90.7
Adult Salivary Gland
493.7
Adult Heart
92.125
Adult VirginFemale Spermatheca
100.3
Adult InseminatedFemale Spermatheca
97.4
Adult Ovary
407
Adult Testis
136.1
Adult Male Accessory Gland
149.1
Adult Carcass
242
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
173.325
Larval Midgut
(999.1)
Larval Hindgut
647.7
Larval Malpighian Tubules
703.6
Larval Fat Body
254.6
Larval Salivary Gland
183.9
Larval Trachea
230.4
Larval Carcass
221.4
Adult Head
259.1
Adult Eye
316.225
Adult Brain
341.4
Adult Thoracic-Abdominal Ganglion
242.2
Adult Crop
232.8
Adult Midgut
697.8
Adult Hindgut
327.1
Adult Malpighian Tubules
(1297.2)
Adult Fat Body
90.7
Adult Salivary Gland
493.7
Adult Heart
92.125
Adult VirginFemale Spermatheca
100.3
Adult InseminatedFemale Spermatheca
97.4
Adult Ovary
407
Adult Testis
136.1
Adult Male Accessory Gland
149.1
Adult Carcass
242
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
173.325
Larval Midgut
999.1
Larval Hindgut
647.7
Larval Malpighian Tubules
703.6
Larval Fat Body
254.6
Larval Salivary Gland
183.9
Larval Trachea
230.4
Larval Carcass
221.4
Adult Head
259.1
Adult Eye
316.225
Adult Brain
341.4
Adult Thoracic-Abdominal Ganglion
242.2
Adult Crop
232.8
Adult Midgut
697.8
Adult Hindgut
327.1
Adult Malpighian Tubules
1297.2
Adult Fat Body
90.7
Adult Salivary Gland
493.7
Adult Heart
92.125
Adult VirginFemale Spermatheca
100.3
Adult InseminatedFemale Spermatheca
97.4
Adult Ovary
407
Adult Testis
136.1
Adult Male Accessory Gland
149.1
Adult Carcass
242
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
173.325
Larval Midgut
999.1
Larval Hindgut
647.7
Larval Malpighian Tubules
703.6
Larval Fat Body
254.6
Larval Salivary Gland
183.9
Larval Trachea
230.4
Larval Carcass
221.4
Adult Head
259.1
Adult Eye
316.225
Adult Brain
341.4
Adult Thoracic-Abdominal Ganglion
242.2
Adult Crop
232.8
Adult Midgut
697.8
Adult Hindgut
327.1
Adult Malpighian Tubules
1297.2
Adult Fat Body
90.7
Adult Salivary Gland
493.7
Adult Heart
92.125
Adult VirginFemale Spermatheca
100.3
Adult InseminatedFemale Spermatheca
97.4
Adult Ovary
407
Adult Testis
136.1
Adult Male Accessory Gland
149.1
Adult Carcass
242
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
259.1
NA
Eye
316.225
NA
Brain
341.4
173.325
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
242.2
NA
Crop
232.8
999.1
Midgut
697.8
647.7
Hindgut
327.1
703.6
Malpighian Tubules
1297.2
254.6
Fat Body
90.7
183.9
Salivary Gland
493.7
NA
Heart
92.125
230.4
Trachea
NA
NA
VirginFemale Spermatheca
100.3
NA
InseminatedFemale Spermatheca
97.4
NA
Ovary
407
NA
Testis
136.1
NA
Male Accessory Gland
149.1
221.4
Carcass
242
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
81
central nervous system, larvae L3
28
central nervous system, pupae P8
27
head, virgin 1-day female
38
head, virgin 4-day female
38
head, virgin 20-day female
36
head, mated 1-day female
34
head, mated 4-day female
32
head, mated 20-day female
31
head, mated 1-day male
57
head, mated 4-day male
62
head, mated 20-day male
64
salivary gland, larvae L3 wandering
6
salivary gland, white prepupae
35
digestive system, larvae L3 wandering
128
digestive system, 1-day adult
64
digestive system, 4-day adult
61
digestive system, 20-day adult
63
fat body, larvae L3 wandering
11
fat body, white prepupae
58
fat body, pupae P8
25
carcass, larvae L3 wandering
36
carcass, 1-day adult
30
carcass, 4-day adult
33
carcass, 20-day adult
32
ovary, virgin 4-day female
103
ovary, mated 4-day female
82
testis, mated 4-day male
84
accessory gland, mated 4-day male
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(81)
central nervous system, larvae L3
(28)
central nervous system, pupae P8
(27)
head, virgin 1-day female
(38)
head, virgin 4-day female
(38)
head, virgin 20-day female
(36)
head, mated 1-day female
(34)
head, mated 4-day female
(32)
head, mated 20-day female
(31)
head, mated 1-day male
(57)
head, mated 4-day male
(62)
head, mated 20-day male
(64)
salivary gland, larvae L3 wandering
6
salivary gland, white prepupae
(35)
digestive system, larvae L3 wandering
(128)
digestive system, 1-day adult
(64)
digestive system, 4-day adult
(61)
digestive system, 20-day adult
(63)
fat body, larvae L3 wandering
11
fat body, white prepupae
(58)
fat body, pupae P8
25
carcass, larvae L3 wandering
(36)
carcass, 1-day adult
(30)
carcass, 4-day adult
(33)
carcass, 20-day adult
(32)
ovary, virgin 4-day female
(103)
ovary, mated 4-day female
(82)
testis, mated 4-day male
(84)
accessory gland, mated 4-day male
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
81
central nervous system, larvae L3
28
central nervous system, pupae P8
27
head, virgin 1-day female
38
head, virgin 4-day female
38
head, virgin 20-day female
36
head, mated 1-day female
34
head, mated 4-day female
32
head, mated 20-day female
31
head, mated 1-day male
57
head, mated 4-day male
62
head, mated 20-day male
64
salivary gland, larvae L3 wandering
6
salivary gland, white prepupae
35
digestive system, larvae L3 wandering
(128)
digestive system, 1-day adult
64
digestive system, 4-day adult
61
digestive system, 20-day adult
63
fat body, larvae L3 wandering
11
fat body, white prepupae
58
fat body, pupae P8
25
carcass, larvae L3 wandering
36
carcass, 1-day adult
30
carcass, 4-day adult
33
carcass, 20-day adult
32
ovary, virgin 4-day female
103
ovary, mated 4-day female
82
testis, mated 4-day male
84
accessory gland, mated 4-day male
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
81
central nervous system, larvae L3
28
central nervous system, pupae P8
27
head, virgin 1-day female
38
head, virgin 4-day female
38
head, virgin 20-day female
36
head, mated 1-day female
34
head, mated 4-day female
32
head, mated 20-day female
31
head, mated 1-day male
57
head, mated 4-day male
62
head, mated 20-day male
64
salivary gland, larvae L3 wandering
6
salivary gland, white prepupae
35
digestive system, larvae L3 wandering
128
digestive system, 1-day adult
64
digestive system, 4-day adult
61
digestive system, 20-day adult
63
fat body, larvae L3 wandering
11
fat body, white prepupae
58
fat body, pupae P8
25
carcass, larvae L3 wandering
36
carcass, 1-day adult
30
carcass, 4-day adult
33
carcass, 20-day adult
32
ovary, virgin 4-day female
103
ovary, mated 4-day female
82
testis, mated 4-day male
84
accessory gland, mated 4-day male
23
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
81
central nervous system, larvae L3
28
central nervous system, pupae P8
27
head, virgin 1-day female
38
head, virgin 4-day female
38
head, virgin 20-day female
36
head, mated 1-day female
34
head, mated 4-day female
32
head, mated 20-day female
31
head, mated 1-day male
57
head, mated 4-day male
62
head, mated 20-day male
64
salivary gland, larvae L3 wandering
6
salivary gland, white prepupae
35
digestive system, larvae L3 wandering
128
digestive system, 1-day adult
64
digestive system, 4-day adult
61
digestive system, 20-day adult
63
fat body, larvae L3 wandering
11
fat body, white prepupae
58
fat body, pupae P8
25
carcass, larvae L3 wandering
36
carcass, 1-day adult
30
carcass, 4-day adult
33
carcass, 20-day adult
32
ovary, virgin 4-day female
103
ovary, mated 4-day female
82
testis, mated 4-day male
84
accessory gland, mated 4-day male
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(81)
central nervous system, larvae L3
28
central nervous system, pupae P8
27
head, virgin 1-day female
(38)
head, virgin 4-day female
(38)
head, virgin 20-day female
(36)
head, mated 1-day female
(34)
head, mated 4-day female
32
head, mated 20-day female
31
head, mated 1-day male
(57)
head, mated 4-day male
(62)
head, mated 20-day male
(64)
salivary gland, larvae L3 wandering
6
salivary gland, white prepupae
(35)
digestive system, larvae L3 wandering
(128)
digestive system, 1-day adult
(64)
digestive system, 4-day adult
(61)
digestive system, 20-day adult
(63)
fat body, larvae L3 wandering
11
fat body, white prepupae
(58)
fat body, pupae P8
25
carcass, larvae L3 wandering
(36)
carcass, 1-day adult
30
carcass, 4-day adult
(33)
carcass, 20-day adult
32
ovary, virgin 4-day female
(103)
ovary, mated 4-day female
(82)
testis, mated 4-day male
(84)
accessory gland, mated 4-day male
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
81
central nervous system, larvae L3
28
central nervous system, pupae P8
27
head, virgin 1-day female
38
head, virgin 4-day female
38
head, virgin 20-day female
36
head, mated 1-day female
34
head, mated 4-day female
32
head, mated 20-day female
31
head, mated 1-day male
57
head, mated 4-day male
62
head, mated 20-day male
64
salivary gland, larvae L3 wandering
6
salivary gland, white prepupae
35
digestive system, larvae L3 wandering
128
digestive system, 1-day adult
64
digestive system, 4-day adult
61
digestive system, 20-day adult
63
fat body, larvae L3 wandering
11
fat body, white prepupae
58
fat body, pupae P8
25
carcass, larvae L3 wandering
36
carcass, 1-day adult
30
carcass, 4-day adult
33
carcass, 20-day adult
32
ovary, virgin 4-day female
103
ovary, mated 4-day female
82
testis, mated 4-day male
84
accessory gland, mated 4-day male
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
81
central nervous system, larvae L3
28
central nervous system, pupae P8
27
head, virgin 1-day female
38
head, virgin 4-day female
38
head, virgin 20-day female
36
head, mated 1-day female
34
head, mated 4-day female
32
head, mated 20-day female
31
head, mated 1-day male
57
head, mated 4-day male
62
head, mated 20-day male
64
salivary gland, larvae L3 wandering
6
salivary gland, white prepupae
35
digestive system, larvae L3 wandering
128
digestive system, 1-day adult
64
digestive system, 4-day adult
61
digestive system, 20-day adult
63
fat body, larvae L3 wandering
11
fat body, white prepupae
58
fat body, pupae P8
25
carcass, larvae L3 wandering
36
carcass, 1-day adult
30
carcass, 4-day adult
33
carcass, 20-day adult
32
ovary, virgin 4-day female
103
ovary, mated 4-day female
82
testis, mated 4-day male
84
accessory gland, mated 4-day male
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
42
embryo 02-04hr
19
embryo 04-06hr
14
embryo 06-08hr
30
embryo 08-10hr
33
embryo 10-12hr
30
embryo 12-14hr
25
embryo 14-16hr
22
embryo 16-18hr
30
embryo 18-20hr
47
embryo 20-22hr
24
embryo 22-24hr
27
larva L1
16
larva L2
15
larva L3 12hr old
15
larva L3 puffstage 1-2
21
larva L3 puffstage 3-6
35
larva L3 puffstage 7-9
38
white prepupae new
36
white prepupae 12hr
45
white prepupae 24hr
34
pupae 2d postWPP
35
pupae 3d postWPP
27
pupae 4d postWPP
42
adult male 01day
40
adult male 05day
53
adult male 30day
48
adult female 01day
28
adult female 05day
36
adult female 30day
38
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(42)
embryo 02-04hr
19
embryo 04-06hr
14
embryo 06-08hr
(30)
embryo 08-10hr
(33)
embryo 10-12hr
(30)
embryo 12-14hr
25
embryo 14-16hr
22
embryo 16-18hr
(30)
embryo 18-20hr
(47)
embryo 20-22hr
24
embryo 22-24hr
(27)
larva L1
16
larva L2
15
larva L3 12hr old
15
larva L3 puffstage 1-2
21
larva L3 puffstage 3-6
(35)
larva L3 puffstage 7-9
(38)
white prepupae new
(36)
white prepupae 12hr
(45)
white prepupae 24hr
(34)
pupae 2d postWPP
(35)
pupae 3d postWPP
(27)
pupae 4d postWPP
(42)
adult male 01day
(40)
adult male 05day
(53)
adult male 30day
(48)
adult female 01day
(28)
adult female 05day
(36)
adult female 30day
(38)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
42
embryo 02-04hr
19
embryo 04-06hr
14
embryo 06-08hr
30
embryo 08-10hr
33
embryo 10-12hr
30
embryo 12-14hr
25
embryo 14-16hr
22
embryo 16-18hr
30
embryo 18-20hr
47
embryo 20-22hr
24
embryo 22-24hr
27
larva L1
16
larva L2
15
larva L3 12hr old
15
larva L3 puffstage 1-2
21
larva L3 puffstage 3-6
35
larva L3 puffstage 7-9
38
white prepupae new
36
white prepupae 12hr
45
white prepupae 24hr
34
pupae 2d postWPP
35
pupae 3d postWPP
27
pupae 4d postWPP
42
adult male 01day
40
adult male 05day
53
adult male 30day
48
adult female 01day
28
adult female 05day
36
adult female 30day
38
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
42
embryo 02-04hr
19
embryo 04-06hr
14
embryo 06-08hr
30
embryo 08-10hr
33
embryo 10-12hr
30
embryo 12-14hr
25
embryo 14-16hr
22
embryo 16-18hr
30
embryo 18-20hr
47
embryo 20-22hr
24
embryo 22-24hr
27
larva L1
16
larva L2
15
larva L3 12hr old
15
larva L3 puffstage 1-2
21
larva L3 puffstage 3-6
35
larva L3 puffstage 7-9
38
white prepupae new
36
white prepupae 12hr
45
white prepupae 24hr
34
pupae 2d postWPP
35
pupae 3d postWPP
27
pupae 4d postWPP
42
adult male 01day
40
adult male 05day
53
adult male 30day
48
adult female 01day
28
adult female 05day
36
adult female 30day
38
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
42
embryo 02-04hr
19
embryo 04-06hr
14
embryo 06-08hr
30
embryo 08-10hr
33
embryo 10-12hr
30
embryo 12-14hr
25
embryo 14-16hr
22
embryo 16-18hr
30
embryo 18-20hr
47
embryo 20-22hr
24
embryo 22-24hr
27
larva L1
16
larva L2
15
larva L3 12hr old
15
larva L3 puffstage 1-2
21
larva L3 puffstage 3-6
35
larva L3 puffstage 7-9
38
white prepupae new
36
white prepupae 12hr
45
white prepupae 24hr
34
pupae 2d postWPP
35
pupae 3d postWPP
27
pupae 4d postWPP
42
adult male 01day
40
adult male 05day
53
adult male 30day
48
adult female 01day
28
adult female 05day
36
adult female 30day
38
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(42)
embryo 02-04hr
19
embryo 04-06hr
14
embryo 06-08hr
30
embryo 08-10hr
(33)
embryo 10-12hr
30
embryo 12-14hr
25
embryo 14-16hr
22
embryo 16-18hr
30
embryo 18-20hr
(47)
embryo 20-22hr
24
embryo 22-24hr
27
larva L1
16
larva L2
15
larva L3 12hr old
15
larva L3 puffstage 1-2
21
larva L3 puffstage 3-6
(35)
larva L3 puffstage 7-9
(38)
white prepupae new
(36)
white prepupae 12hr
(45)
white prepupae 24hr
(34)
pupae 2d postWPP
(35)
pupae 3d postWPP
27
pupae 4d postWPP
(42)
adult male 01day
(40)
adult male 05day
(53)
adult male 30day
(48)
adult female 01day
28
adult female 05day
(36)
adult female 30day
(38)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
42
embryo 02-04hr
19
embryo 04-06hr
14
embryo 06-08hr
30
embryo 08-10hr
33
embryo 10-12hr
30
embryo 12-14hr
25
embryo 14-16hr
22
embryo 16-18hr
30
embryo 18-20hr
47
embryo 20-22hr
24
embryo 22-24hr
27
larva L1
16
larva L2
15
larva L3 12hr old
15
larva L3 puffstage 1-2
21
larva L3 puffstage 3-6
35
larva L3 puffstage 7-9
38
white prepupae new
36
white prepupae 12hr
45
white prepupae 24hr
34
pupae 2d postWPP
35
pupae 3d postWPP
27
pupae 4d postWPP
42
adult male 01day
40
adult male 05day
53
adult male 30day
48
adult female 01day
28
adult female 05day
36
adult female 30day
38
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
42
embryo 02-04hr
19
embryo 04-06hr
14
embryo 06-08hr
30
embryo 08-10hr
33
embryo 10-12hr
30
embryo 12-14hr
25
embryo 14-16hr
22
embryo 16-18hr
30
embryo 18-20hr
47
embryo 20-22hr
24
embryo 22-24hr
27
larva L1
16
larva L2
15
larva L3 12hr old
15
larva L3 puffstage 1-2
21
larva L3 puffstage 3-6
35
larva L3 puffstage 7-9
38
white prepupae new
36
white prepupae 12hr
45
white prepupae 24hr
34
pupae 2d postWPP
35
pupae 3d postWPP
27
pupae 4d postWPP
42
adult male 01day
40
adult male 05day
53
adult male 30day
48
adult female 01day
28
adult female 05day
36
adult female 30day
38
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
16
Schneider line 2 Sg4
17
embryonic 1182-4H
49
embryonic GM2
47
embryonic Kc167
32
embryonic S1
39
embryonic S3
15
leg disc CME L1
19
wing disc CME-W2
33
wing disc ML-DmD8
23
wing disc ML-DmD9
30
wing disc ML-DmD16-c3
33
wing disc ML-DmD21
22
wing disc ML-DmD32
37
haltere disc ML-DmD17-c3
30
eye-antennal disc ML-DmD11
27
antennal disc ML-DmD20-c5
34
mixed discs ML-DmD4-c1
19
CNS ML-DmBG1-c1
24
CNS ML-DmBG2-c2
34
tumorous blood cells mbn2
16
ovary fGS/OSS
12
ovary OSC
17
ovary OSS
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
16
Schneider line 2 Sg4
17
embryonic 1182-4H
(49)
embryonic GM2
(47)
embryonic Kc167
(32)
embryonic S1
(39)
embryonic S3
15
leg disc CME L1
19
wing disc CME-W2
(33)
wing disc ML-DmD8
23
wing disc ML-DmD9
(30)
wing disc ML-DmD16-c3
(33)
wing disc ML-DmD21
22
wing disc ML-DmD32
(37)
haltere disc ML-DmD17-c3
(30)
eye-antennal disc ML-DmD11
(27)
antennal disc ML-DmD20-c5
(34)
mixed discs ML-DmD4-c1
19
CNS ML-DmBG1-c1
24
CNS ML-DmBG2-c2
(34)
tumorous blood cells mbn2
16
ovary fGS/OSS
12
ovary OSC
17
ovary OSS
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
16
Schneider line 2 Sg4
17
embryonic 1182-4H
49
embryonic GM2
47
embryonic Kc167
32
embryonic S1
39
embryonic S3
15
leg disc CME L1
19
wing disc CME-W2
33
wing disc ML-DmD8
23
wing disc ML-DmD9
30
wing disc ML-DmD16-c3
33
wing disc ML-DmD21
22
wing disc ML-DmD32
37
haltere disc ML-DmD17-c3
30
eye-antennal disc ML-DmD11
27
antennal disc ML-DmD20-c5
34
mixed discs ML-DmD4-c1
19
CNS ML-DmBG1-c1
24
CNS ML-DmBG2-c2
34
tumorous blood cells mbn2
16
ovary fGS/OSS
12
ovary OSC
17
ovary OSS
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
16
Schneider line 2 Sg4
17
embryonic 1182-4H
49
embryonic GM2
47
embryonic Kc167
32
embryonic S1
39
embryonic S3
15
leg disc CME L1
19
wing disc CME-W2
33
wing disc ML-DmD8
23
wing disc ML-DmD9
30
wing disc ML-DmD16-c3
33
wing disc ML-DmD21
22
wing disc ML-DmD32
37
haltere disc ML-DmD17-c3
30
eye-antennal disc ML-DmD11
27
antennal disc ML-DmD20-c5
34
mixed discs ML-DmD4-c1
19
CNS ML-DmBG1-c1
24
CNS ML-DmBG2-c2
34
tumorous blood cells mbn2
16
ovary fGS/OSS
12
ovary OSC
17
ovary OSS
5
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
16
Schneider line 2 Sg4
17
embryonic 1182-4H
49
embryonic GM2
47
embryonic Kc167
32
embryonic S1
39
embryonic S3
15
leg disc CME L1
19
wing disc CME-W2
33
wing disc ML-DmD8
23
wing disc ML-DmD9
30
wing disc ML-DmD16-c3
33
wing disc ML-DmD21
22
wing disc ML-DmD32
37
haltere disc ML-DmD17-c3
30
eye-antennal disc ML-DmD11
27
antennal disc ML-DmD20-c5
34
mixed discs ML-DmD4-c1
19
CNS ML-DmBG1-c1
24
CNS ML-DmBG2-c2
34
tumorous blood cells mbn2
16
ovary fGS/OSS
12
ovary OSC
17
ovary OSS
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
16
Schneider line 2 Sg4
17
embryonic 1182-4H
(49)
embryonic GM2
(47)
embryonic Kc167
32
embryonic S1
(39)
embryonic S3
15
leg disc CME L1
19
wing disc CME-W2
(33)
wing disc ML-DmD8
23
wing disc ML-DmD9
30
wing disc ML-DmD16-c3
(33)
wing disc ML-DmD21
22
wing disc ML-DmD32
(37)
haltere disc ML-DmD17-c3
30
eye-antennal disc ML-DmD11
27
antennal disc ML-DmD20-c5
(34)
mixed discs ML-DmD4-c1
19
CNS ML-DmBG1-c1
24
CNS ML-DmBG2-c2
(34)
tumorous blood cells mbn2
16
ovary fGS/OSS
12
ovary OSC
17
ovary OSS
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
16
Schneider line 2 Sg4
17
embryonic 1182-4H
49
embryonic GM2
47
embryonic Kc167
32
embryonic S1
39
embryonic S3
15
leg disc CME L1
19
wing disc CME-W2
33
wing disc ML-DmD8
23
wing disc ML-DmD9
30
wing disc ML-DmD16-c3
33
wing disc ML-DmD21
22
wing disc ML-DmD32
37
haltere disc ML-DmD17-c3
30
eye-antennal disc ML-DmD11
27
antennal disc ML-DmD20-c5
34
mixed discs ML-DmD4-c1
19
CNS ML-DmBG1-c1
24
CNS ML-DmBG2-c2
34
tumorous blood cells mbn2
16
ovary fGS/OSS
12
ovary OSC
17
ovary OSS
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
16
Schneider line 2 Sg4
17
embryonic 1182-4H
49
embryonic GM2
47
embryonic Kc167
32
embryonic S1
39
embryonic S3
15
leg disc CME L1
19
wing disc CME-W2
33
wing disc ML-DmD8
23
wing disc ML-DmD9
30
wing disc ML-DmD16-c3
33
wing disc ML-DmD21
22
wing disc ML-DmD32
37
haltere disc ML-DmD17-c3
30
eye-antennal disc ML-DmD11
27
antennal disc ML-DmD20-c5
34
mixed discs ML-DmD4-c1
19
CNS ML-DmBG1-c1
24
CNS ML-DmBG2-c2
34
tumorous blood cells mbn2
16
ovary fGS/OSS
12
ovary OSC
17
ovary OSS
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
34
cold shock, 4-day adult
30
heat shock, 4-day adult
40
Cadmium 50 mM 6 hrs, larvae L3
34
Cadmium 50 mM 12 hrs, larvae L3
47
Cadmium 50 mM 48 hrs, 4-day adult
42
Cadmium 100 mM 48 hrs, 4-day adult
70
Copper 0.5 mM 12 hrs, larvae L3
24
Copper 15 mM 48 hrs, 4-day adult
56
Zinc 5 mM 12 hrs, larvae L3
16
Zinc 4.5 mM 48 hrs, 4-day adult
45
Ethanol 2.5% 3 hrs, larvae L3
54
Ethanol 5% 3 hrs, larvae L3
42
Ethanol 10% 3 hrs, larvae L3
28
Caffeine 1.5 mg/ml 4 hrs, larvae L3
45
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
64
Caffeine 25 mg/ml 48 hrs, 4-day adult
33
Paraquat 5 mM 48 hrs, 4-day adult
61
Paraquat 10 mM 48 hrs, 4-day adult
59
Rotenone 2 μg 12 hrs, larvae L3
38
Rotenone 8 μg 12 hrs, larvae L3
27
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
(34)
cold shock, 4-day adult
(30)
heat shock, 4-day adult
(40)
Cadmium 50 mM 6 hrs, larvae L3
(34)
Cadmium 50 mM 12 hrs, larvae L3
(47)
Cadmium 50 mM 48 hrs, 4-day adult
(42)
Cadmium 100 mM 48 hrs, 4-day adult
(70)
Copper 0.5 mM 12 hrs, larvae L3
24
Copper 15 mM 48 hrs, 4-day adult
(56)
Zinc 5 mM 12 hrs, larvae L3
16
Zinc 4.5 mM 48 hrs, 4-day adult
(45)
Ethanol 2.5% 3 hrs, larvae L3
(54)
Ethanol 5% 3 hrs, larvae L3
(42)
Ethanol 10% 3 hrs, larvae L3
(28)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(45)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(64)
Caffeine 25 mg/ml 48 hrs, 4-day adult
(33)
Paraquat 5 mM 48 hrs, 4-day adult
(61)
Paraquat 10 mM 48 hrs, 4-day adult
(59)
Rotenone 2 μg 12 hrs, larvae L3
(38)
Rotenone 8 μg 12 hrs, larvae L3
(27)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
34
cold shock, 4-day adult
30
heat shock, 4-day adult
40
Cadmium 50 mM 6 hrs, larvae L3
34
Cadmium 50 mM 12 hrs, larvae L3
47
Cadmium 50 mM 48 hrs, 4-day adult
42
Cadmium 100 mM 48 hrs, 4-day adult
70
Copper 0.5 mM 12 hrs, larvae L3
24
Copper 15 mM 48 hrs, 4-day adult
56
Zinc 5 mM 12 hrs, larvae L3
16
Zinc 4.5 mM 48 hrs, 4-day adult
45
Ethanol 2.5% 3 hrs, larvae L3
54
Ethanol 5% 3 hrs, larvae L3
42
Ethanol 10% 3 hrs, larvae L3
28
Caffeine 1.5 mg/ml 4 hrs, larvae L3
45
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
64
Caffeine 25 mg/ml 48 hrs, 4-day adult
33
Paraquat 5 mM 48 hrs, 4-day adult
61
Paraquat 10 mM 48 hrs, 4-day adult
59
Rotenone 2 μg 12 hrs, larvae L3
38
Rotenone 8 μg 12 hrs, larvae L3
27
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
34
cold shock, 4-day adult
30
heat shock, 4-day adult
40
Cadmium 50 mM 6 hrs, larvae L3
34
Cadmium 50 mM 12 hrs, larvae L3
47
Cadmium 50 mM 48 hrs, 4-day adult
42
Cadmium 100 mM 48 hrs, 4-day adult
70
Copper 0.5 mM 12 hrs, larvae L3
24
Copper 15 mM 48 hrs, 4-day adult
56
Zinc 5 mM 12 hrs, larvae L3
16
Zinc 4.5 mM 48 hrs, 4-day adult
45
Ethanol 2.5% 3 hrs, larvae L3
54
Ethanol 5% 3 hrs, larvae L3
42
Ethanol 10% 3 hrs, larvae L3
28
Caffeine 1.5 mg/ml 4 hrs, larvae L3
45
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
64
Caffeine 25 mg/ml 48 hrs, 4-day adult
33
Paraquat 5 mM 48 hrs, 4-day adult
61
Paraquat 10 mM 48 hrs, 4-day adult
59
Rotenone 2 μg 12 hrs, larvae L3
38
Rotenone 8 μg 12 hrs, larvae L3
27
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
34
cold shock, 4-day adult
30
heat shock, 4-day adult
40
Cadmium 50 mM 6 hrs, larvae L3
34
Cadmium 50 mM 12 hrs, larvae L3
47
Cadmium 50 mM 48 hrs, 4-day adult
42
Cadmium 100 mM 48 hrs, 4-day adult
70
Copper 0.5 mM 12 hrs, larvae L3
24
Copper 15 mM 48 hrs, 4-day adult
56
Zinc 5 mM 12 hrs, larvae L3
16
Zinc 4.5 mM 48 hrs, 4-day adult
45
Ethanol 2.5% 3 hrs, larvae L3
54
Ethanol 5% 3 hrs, larvae L3
42
Ethanol 10% 3 hrs, larvae L3
28
Caffeine 1.5 mg/ml 4 hrs, larvae L3
45
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
64
Caffeine 25 mg/ml 48 hrs, 4-day adult
33
Paraquat 5 mM 48 hrs, 4-day adult
61
Paraquat 10 mM 48 hrs, 4-day adult
59
Rotenone 2 μg 12 hrs, larvae L3
38
Rotenone 8 μg 12 hrs, larvae L3
27
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
(34)
cold shock, 4-day adult
30
heat shock, 4-day adult
(40)
Cadmium 50 mM 6 hrs, larvae L3
(34)
Cadmium 50 mM 12 hrs, larvae L3
(47)
Cadmium 50 mM 48 hrs, 4-day adult
(42)
Cadmium 100 mM 48 hrs, 4-day adult
(70)
Copper 0.5 mM 12 hrs, larvae L3
24
Copper 15 mM 48 hrs, 4-day adult
(56)
Zinc 5 mM 12 hrs, larvae L3
16
Zinc 4.5 mM 48 hrs, 4-day adult
(45)
Ethanol 2.5% 3 hrs, larvae L3
(54)
Ethanol 5% 3 hrs, larvae L3
(42)
Ethanol 10% 3 hrs, larvae L3
28
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(45)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(64)
Caffeine 25 mg/ml 48 hrs, 4-day adult
(33)
Paraquat 5 mM 48 hrs, 4-day adult
(61)
Paraquat 10 mM 48 hrs, 4-day adult
(59)
Rotenone 2 μg 12 hrs, larvae L3
(38)
Rotenone 8 μg 12 hrs, larvae L3
27
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
34
cold shock, 4-day adult
30
heat shock, 4-day adult
40
Cadmium 50 mM 6 hrs, larvae L3
34
Cadmium 50 mM 12 hrs, larvae L3
47
Cadmium 50 mM 48 hrs, 4-day adult
42
Cadmium 100 mM 48 hrs, 4-day adult
70
Copper 0.5 mM 12 hrs, larvae L3
24
Copper 15 mM 48 hrs, 4-day adult
56
Zinc 5 mM 12 hrs, larvae L3
16
Zinc 4.5 mM 48 hrs, 4-day adult
45
Ethanol 2.5% 3 hrs, larvae L3
54
Ethanol 5% 3 hrs, larvae L3
42
Ethanol 10% 3 hrs, larvae L3
28
Caffeine 1.5 mg/ml 4 hrs, larvae L3
45
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
64
Caffeine 25 mg/ml 48 hrs, 4-day adult
33
Paraquat 5 mM 48 hrs, 4-day adult
61
Paraquat 10 mM 48 hrs, 4-day adult
59
Rotenone 2 μg 12 hrs, larvae L3
38
Rotenone 8 μg 12 hrs, larvae L3
27
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
34
cold shock, 4-day adult
30
heat shock, 4-day adult
40
Cadmium 50 mM 6 hrs, larvae L3
34
Cadmium 50 mM 12 hrs, larvae L3
47
Cadmium 50 mM 48 hrs, 4-day adult
42
Cadmium 100 mM 48 hrs, 4-day adult
70
Copper 0.5 mM 12 hrs, larvae L3
24
Copper 15 mM 48 hrs, 4-day adult
56
Zinc 5 mM 12 hrs, larvae L3
16
Zinc 4.5 mM 48 hrs, 4-day adult
45
Ethanol 2.5% 3 hrs, larvae L3
54
Ethanol 5% 3 hrs, larvae L3
42
Ethanol 10% 3 hrs, larvae L3
28
Caffeine 1.5 mg/ml 4 hrs, larvae L3
45
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
64
Caffeine 25 mg/ml 48 hrs, 4-day adult
33
Paraquat 5 mM 48 hrs, 4-day adult
61
Paraquat 10 mM 48 hrs, 4-day adult
59
Rotenone 2 μg 12 hrs, larvae L3
38
Rotenone 8 μg 12 hrs, larvae L3
27
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 6 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 3 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Disrupted in Transgenic Constructs & Insertions
Transgenic Constructs Insertions insertion of mobile activating element
insertion of enhancer trap binary system
Gene Ontology: Function, Process
& Cellular Component ( 1 unique term ) Terms Based on
Experimental Evidence ( 0 terms ) Terms Based on Predictions or
Assertions ( 1 term ) Molecular Function ( 0 terms) Biological Process Cellular Component ( 0 terms) Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
Orthologs
OrthoDB Orthologs (30)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
No orthologs identified
Orthologs in Drosophila Species
(EOG65TD7D )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG6JWVPF )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG6S4NC4 )
Apis mellifera
Western honey bee
Amel\GB48369
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG005983
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH13944
Atta cephalotes
Leafcutter ant
Acep\ACEP16261
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO17739
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL20827
Linepithema humile
Argentine ant
Lhum\LH22321
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB19593
Solenopsis invicta
Red fire ant
Sinv\SINV19414
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG6RV177 )
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)AAA Orthologs (10)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 5 )Bloomington Harvard VDRC Genomic Clones ( 2 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 97 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for database merge of Additional comments FlyBase curator comment: The molecular map shown in Figure 4. of
FBrf0054607 indicates that the "red" transcription unit must map between
trx and
su(Hw) . The release 5.19 D.melanogaster genome has two annotations in this region - CG12207 and CG3259, one of which likely corresponds to "red". Molecular mapping of "red" mutations suggest that it is more likely that "red" corresponds to CG12207 rather than "CG3259".
Other Comments RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 1 )Reported As Symbol Synonym Name Synonym Secondary FlyBase
IDs References ( 23 )Generate a list of List References by type
Recent research papers (0)
All research papers listed in FlyBase were published before 2011