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Gene Dmel\CG3508

General Information
Symbol	Dmel\CG3508	Species	D. melanogaster
Name		Annotation symbol	CG3508
Feature type	protein_coding_gene	FlyBase ID	FBgn0038251
Gene Model Status	Current	Stock availability	8 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	88C10-88C10	Sequence location	3R:10,485,163..10,486,899 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG3508 (FBgn0038251). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult hindgut, adult heart, larval trachea, adult ovary, adult testis, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1638651_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG3508. Gene sequence location is 3R:10485163..10486899.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features HFA15490 BKN25491
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 88C10-88C10   Limits computationally determined from genome sequence between P{PZ}put10460 and P{EP}CG33967EP666
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG3508 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.39
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG3508-RA FBtr0082967  NM_142124   1512   349 CG3508-RB FBtr0082968  NM_169595   1545   360
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG3508-PA   FBpp0082426   38.1   349   7.67     NP_650381   AAF55085 CG3508-PB   FBpp0082427   39.2   360   8.35     NP_731932   AAN13614
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA246631   AA246921   AA247053   AA264611   AA950637   AE014297 AAF55085   AE014297 AAN13614   AI389618   AI517870   AI534551   AW943035   AY051786 AAK93210   BI162465   BI162788   BI168289   BI170214   BI230354   BI230766   BI373785   BI485927   BI573904   BI578443   BI580435   BI581888   BI581923   BI611813   BI613408   BT001551 AAN71306   CK132220   CL868623   EV596615   GH747698   GH747766   GH749023   GH752749   GH755067   GH756338   GH759219   GH772602   GH773384   GH774603   GH778459   GH778485   GH784630   GH784992   GH785518   GH786669   GH790535   GH791286   GH792485   GH797179   GH798816   GH802362   GH803847   GH805812   GH806182   GH810339   GH810343   GH810888   GH811878   GH812859   GH815548   GH815872   GH820638   GH822132   GH822994   GH825135   GH826854   GH838311   GH843687   GH845525   GH846827   GH847895   GH848137   GH849719   GH852601   GH854609   GH855536   GH857036   GH857039   GH857623   GH859880   GH862427   GH864944   GH865685   GH868893   GH869964   GH870722   GH871066   GH874750   GH874896   GH874990   GH877474   GH881133   GH884098   GH885449   GH885767   GH888909   GH906333   GH906461   GH907141   GH908616   GH909477   GH909699   GH910863   GH911687   GH912465   GH912635   GH915248   GH915264   GH920143   GH920745   GH921684   GH922048   GH922731   GH924525   GH927366   GH928136   GH928257   GH928595   GH933312   GH938164
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8IGW8 Q8INF6 Q9VFH2
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0038251    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0038251 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0038251 expression level Developmental Stage   Expression Level embryo 00-02hr    5335 embryo 02-04hr    3387 embryo 04-06hr    1163 embryo 06-08hr    1527 embryo 08-10hr    2213 embryo 10-12hr    2157 embryo 12-14hr    1400 embryo 14-16hr    1363 embryo 16-18hr    1096 embryo 18-20hr    601 embryo 20-22hr    1351 embryo 22-24hr    887 larva L1    441 larva L2    335 larva L3 12hr old    366 larva L3 puffstage 1-2    540 larva L3 puffstage 3-6    806 larva L3 puffstage 7-9    963 white prepupae new    950 white prepupae 12hr    1393 white prepupae 24hr    1669 pupae 2d postWPP    1296 pupae 3d postWPP    920 pupae 4d postWPP    699 adult male 01day    1013 adult male 05day    1423 adult male 30day    1344 adult female 01day    1402 adult female 05day    2610 adult female 30day    2939 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (5335) embryo 02-04hr  (3387) embryo 04-06hr  (1163) embryo 06-08hr  (1527) embryo 08-10hr  (2213) embryo 10-12hr  (2157) embryo 12-14hr  (1400) embryo 14-16hr  (1363) embryo 16-18hr  (1096) embryo 18-20hr  (601) embryo 20-22hr  (1351) embryo 22-24hr  (887) larva L1  (441) larva L2  (335) larva L3 12hr old  (366) larva L3 puffstage 1-2  (540) larva L3 puffstage 3-6  (806) larva L3 puffstage 7-9  (963) white prepupae new  (950) white prepupae 12hr  (1393) white prepupae 24hr  (1669) pupae 2d postWPP  (1296) pupae 3d postWPP  (920) pupae 4d postWPP  (699) adult male 01day  (1013) adult male 05day  (1423) adult male 30day  (1344) adult female 01day  (1402) adult female 05day  (2610) adult female 30day  (2939) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (5335) embryo 02-04hr  (3387) embryo 04-06hr    1163 embryo 06-08hr  (1527) embryo 08-10hr  (2213) embryo 10-12hr  (2157) embryo 12-14hr    1400 embryo 14-16hr    1363 embryo 16-18hr    1096 embryo 18-20hr    601 embryo 20-22hr    1351 embryo 22-24hr    887 larva L1    441 larva L2    335 larva L3 12hr old    366 larva L3 puffstage 1-2    540 larva L3 puffstage 3-6    806 larva L3 puffstage 7-9    963 white prepupae new    950 white prepupae 12hr    1393 white prepupae 24hr  (1669) pupae 2d postWPP    1296 pupae 3d postWPP    920 pupae 4d postWPP    699 adult male 01day    1013 adult male 05day  1423 adult male 30day    1344 adult female 01day  1402 adult female 05day  (2610) adult female 30day  (2939) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5335 embryo 02-04hr    3387 embryo 04-06hr    1163 embryo 06-08hr    1527 embryo 08-10hr    2213 embryo 10-12hr    2157 embryo 12-14hr    1400 embryo 14-16hr    1363 embryo 16-18hr    1096 embryo 18-20hr    601 embryo 20-22hr    1351 embryo 22-24hr    887 larva L1    441 larva L2    335 larva L3 12hr old    366 larva L3 puffstage 1-2    540 larva L3 puffstage 3-6    806 larva L3 puffstage 7-9    963 white prepupae new    950 white prepupae 12hr    1393 white prepupae 24hr    1669 pupae 2d postWPP    1296 pupae 3d postWPP    920 pupae 4d postWPP    699 adult male 01day    1013 adult male 05day    1423 adult male 30day    1344 adult female 01day    1402 adult female 05day    2610 adult female 30day    2939 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5335 embryo 02-04hr    3387 embryo 04-06hr    1163 embryo 06-08hr    1527 embryo 08-10hr    2213 embryo 10-12hr    2157 embryo 12-14hr    1400 embryo 14-16hr    1363 embryo 16-18hr    1096 embryo 18-20hr    601 embryo 20-22hr    1351 embryo 22-24hr    887 larva L1    441 larva L2    335 larva L3 12hr old    366 larva L3 puffstage 1-2    540 larva L3 puffstage 3-6    806 larva L3 puffstage 7-9    963 white prepupae new    950 white prepupae 12hr    1393 white prepupae 24hr    1669 pupae 2d postWPP    1296 pupae 3d postWPP    920 pupae 4d postWPP    699 adult male 01day    1013 adult male 05day    1423 adult male 30day    1344 adult female 01day    1402 adult female 05day    2610 adult female 30day    2939 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0038251 expression level Developmental Stage   Expression Level embryo 00-02hr    5335 embryo 02-04hr    3387 embryo 04-06hr    1163 embryo 06-08hr    1527 embryo 08-10hr    2213 embryo 10-12hr    2157 embryo 12-14hr    1400 embryo 14-16hr    1363 embryo 16-18hr    1096 embryo 18-20hr    601 embryo 20-22hr    1351 embryo 22-24hr    887 larva L1    441 larva L2    335 larva L3 12hr old    366 larva L3 puffstage 1-2    540 larva L3 puffstage 3-6    806 larva L3 puffstage 7-9    963 white prepupae new    950 white prepupae 12hr    1393 white prepupae 24hr    1669 pupae 2d postWPP    1296 pupae 3d postWPP    920 pupae 4d postWPP    699 adult male 01day    1013 adult male 05day    1423 adult male 30day    1344 adult female 01day    1402 adult female 05day    2610 adult female 30day    2939 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (5335) embryo 02-04hr  (3387) embryo 04-06hr  (1163) embryo 06-08hr  (1527) embryo 08-10hr  (2213) embryo 10-12hr  (2157) embryo 12-14hr  (1400) embryo 14-16hr  (1363) embryo 16-18hr  (1096) embryo 18-20hr  (601) embryo 20-22hr  (1351) embryo 22-24hr  (887) larva L1  (441) larva L2  (335) larva L3 12hr old  (366) larva L3 puffstage 1-2  (540) larva L3 puffstage 3-6  (806) larva L3 puffstage 7-9  (963) white prepupae new  (950) white prepupae 12hr  (1393) white prepupae 24hr  (1669) pupae 2d postWPP  (1296) pupae 3d postWPP  (920) pupae 4d postWPP  (699) adult male 01day  (1013) adult male 05day  (1423) adult male 30day  (1344) adult female 01day  (1402) adult female 05day  (2610) adult female 30day  (2939) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (5335) embryo 02-04hr  (3387) embryo 04-06hr    1163 embryo 06-08hr  1527 embryo 08-10hr  2213 embryo 10-12hr  2157 embryo 12-14hr  1400 embryo 14-16hr    1363 embryo 16-18hr    1096 embryo 18-20hr    601 embryo 20-22hr    1351 embryo 22-24hr    887 larva L1    441 larva L2    335 larva L3 12hr old    366 larva L3 puffstage 1-2    540 larva L3 puffstage 3-6    806 larva L3 puffstage 7-9    963 white prepupae new    950 white prepupae 12hr    1393 white prepupae 24hr  1669 pupae 2d postWPP    1296 pupae 3d postWPP    920 pupae 4d postWPP    699 adult male 01day    1013 adult male 05day  1423 adult male 30day    1344 adult female 01day  1402 adult female 05day  (2610) adult female 30day  (2939) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5335 embryo 02-04hr    3387 embryo 04-06hr    1163 embryo 06-08hr    1527 embryo 08-10hr    2213 embryo 10-12hr    2157 embryo 12-14hr    1400 embryo 14-16hr    1363 embryo 16-18hr    1096 embryo 18-20hr    601 embryo 20-22hr    1351 embryo 22-24hr    887 larva L1    441 larva L2    335 larva L3 12hr old    366 larva L3 puffstage 1-2    540 larva L3 puffstage 3-6    806 larva L3 puffstage 7-9    963 white prepupae new    950 white prepupae 12hr    1393 white prepupae 24hr    1669 pupae 2d postWPP    1296 pupae 3d postWPP    920 pupae 4d postWPP    699 adult male 01day    1013 adult male 05day    1423 adult male 30day    1344 adult female 01day    1402 adult female 05day    2610 adult female 30day    2939 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5335 embryo 02-04hr    3387 embryo 04-06hr    1163 embryo 06-08hr    1527 embryo 08-10hr    2213 embryo 10-12hr    2157 embryo 12-14hr    1400 embryo 14-16hr    1363 embryo 16-18hr    1096 embryo 18-20hr    601 embryo 20-22hr    1351 embryo 22-24hr    887 larva L1    441 larva L2    335 larva L3 12hr old    366 larva L3 puffstage 1-2    540 larva L3 puffstage 3-6    806 larva L3 puffstage 7-9    963 white prepupae new    950 white prepupae 12hr    1393 white prepupae 24hr    1669 pupae 2d postWPP    1296 pupae 3d postWPP    920 pupae 4d postWPP    699 adult male 01day    1013 adult male 05day    1423 adult male 30day    1344 adult female 01day    1402 adult female 05day    2610 adult female 30day    2939 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0038251    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0038251 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult hindgut, adult heart, larval trachea, adult ovary, adult testis, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0038251 expression level Tissue   Expression Level Larval Central Nervous System    150.075 Larval Midgut    47.9 Larval Hindgut    85 Larval Malpighian Tubules    98.6 Larval Fat Body    87.7 Larval Salivary Gland no informative data Larval Trachea    152.475 Larval Carcass    83.375 Adult Head    118.4 Adult Eye    207.25 Adult Brain    157.2 Adult Thoracic-Abdominal Ganglion    160.1 Adult Crop    142.8 Adult Midgut no informative data Adult Hindgut    104 Adult Malpighian Tubules    83.6 Adult Fat Body    82.4 Adult Salivary Gland no informative data Adult Heart    131.875 Adult VirginFemale Spermatheca    92.5 Adult InseminatedFemale Spermatheca    92.3 Adult Ovary    443.1 Adult Testis    210.6 Adult Male Accessory Gland no informative data Adult Carcass    106.2 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    150.075 Larval Midgut    47.9 Larval Hindgut    85 Larval Malpighian Tubules    98.6 Larval Fat Body    87.7 Larval Salivary Gland no informative data Larval Trachea    152.475 Larval Carcass    83.375 Adult Head    118.4 Adult Eye    207.25 Adult Brain    157.2 Adult Thoracic-Abdominal Ganglion    160.1 Adult Crop    142.8 Adult Midgut no informative data Adult Hindgut    104 Adult Malpighian Tubules    83.6 Adult Fat Body    82.4 Adult Salivary Gland no informative data Adult Heart    131.875 Adult VirginFemale Spermatheca    92.5 Adult InseminatedFemale Spermatheca    92.3 Adult Ovary    443.1 Adult Testis    210.6 Adult Male Accessory Gland no informative data Adult Carcass    106.2 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    150.075 Larval Midgut    47.9 Larval Hindgut    85 Larval Malpighian Tubules    98.6 Larval Fat Body    87.7 Larval Salivary Gland no informative data Larval Trachea    152.475 Larval Carcass    83.375 Adult Head    118.4 Adult Eye    207.25 Adult Brain    157.2 Adult Thoracic-Abdominal Ganglion    160.1 Adult Crop    142.8 Adult Midgut no informative data Adult Hindgut    104 Adult Malpighian Tubules    83.6 Adult Fat Body    82.4 Adult Salivary Gland no informative data Adult Heart    131.875 Adult VirginFemale Spermatheca    92.5 Adult InseminatedFemale Spermatheca    92.3 Adult Ovary    443.1 Adult Testis    210.6 Adult Male Accessory Gland no informative data Adult Carcass    106.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    150.075 Larval Midgut    47.9 Larval Hindgut    85 Larval Malpighian Tubules    98.6 Larval Fat Body    87.7 Larval Salivary Gland no informative data Larval Trachea    152.475 Larval Carcass    83.375 Adult Head    118.4 Adult Eye    207.25 Adult Brain    157.2 Adult Thoracic-Abdominal Ganglion    160.1 Adult Crop    142.8 Adult Midgut no informative data Adult Hindgut    104 Adult Malpighian Tubules    83.6 Adult Fat Body    82.4 Adult Salivary Gland no informative data Adult Heart    131.875 Adult VirginFemale Spermatheca    92.5 Adult InseminatedFemale Spermatheca    92.3 Adult Ovary    443.1 Adult Testis    210.6 Adult Male Accessory Gland no informative data Adult Carcass    106.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0038251 expression level Tissue   Expression Level Larval Central Nervous System    150.075 Larval Midgut    47.9 Larval Hindgut    85 Larval Malpighian Tubules    98.6 Larval Fat Body    87.7 Larval Salivary Gland no informative data Larval Trachea    152.475 Larval Carcass    83.375 Adult Head    118.4 Adult Eye    207.25 Adult Brain    157.2 Adult Thoracic-Abdominal Ganglion    160.1 Adult Crop    142.8 Adult Midgut no informative data Adult Hindgut    104 Adult Malpighian Tubules    83.6 Adult Fat Body    82.4 Adult Salivary Gland no informative data Adult Heart    131.875 Adult VirginFemale Spermatheca    92.5 Adult InseminatedFemale Spermatheca    92.3 Adult Ovary    443.1 Adult Testis    210.6 Adult Male Accessory Gland no informative data Adult Carcass    106.2 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    150.075 Larval Midgut    47.9 Larval Hindgut    85 Larval Malpighian Tubules    98.6 Larval Fat Body    87.7 Larval Salivary Gland no informative data Larval Trachea    152.475 Larval Carcass    83.375 Adult Head    118.4 Adult Eye    207.25 Adult Brain    157.2 Adult Thoracic-Abdominal Ganglion    160.1 Adult Crop    142.8 Adult Midgut no informative data Adult Hindgut    104 Adult Malpighian Tubules    83.6 Adult Fat Body    82.4 Adult Salivary Gland no informative data Adult Heart    131.875 Adult VirginFemale Spermatheca    92.5 Adult InseminatedFemale Spermatheca    92.3 Adult Ovary    443.1 Adult Testis    210.6 Adult Male Accessory Gland no informative data Adult Carcass    106.2 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    150.075 Larval Midgut    47.9 Larval Hindgut    85 Larval Malpighian Tubules    98.6 Larval Fat Body    87.7 Larval Salivary Gland no informative data Larval Trachea    152.475 Larval Carcass    83.375 Adult Head    118.4 Adult Eye    207.25 Adult Brain    157.2 Adult Thoracic-Abdominal Ganglion    160.1 Adult Crop    142.8 Adult Midgut no informative data Adult Hindgut    104 Adult Malpighian Tubules    83.6 Adult Fat Body    82.4 Adult Salivary Gland no informative data Adult Heart    131.875 Adult VirginFemale Spermatheca    92.5 Adult InseminatedFemale Spermatheca    92.3 Adult Ovary    443.1 Adult Testis    210.6 Adult Male Accessory Gland no informative data Adult Carcass    106.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    150.075 Larval Midgut    47.9 Larval Hindgut    85 Larval Malpighian Tubules    98.6 Larval Fat Body    87.7 Larval Salivary Gland no informative data Larval Trachea    152.475 Larval Carcass    83.375 Adult Head    118.4 Adult Eye    207.25 Adult Brain    157.2 Adult Thoracic-Abdominal Ganglion    160.1 Adult Crop    142.8 Adult Midgut no informative data Adult Hindgut    104 Adult Malpighian Tubules    83.6 Adult Fat Body    82.4 Adult Salivary Gland no informative data Adult Heart    131.875 Adult VirginFemale Spermatheca    92.5 Adult InseminatedFemale Spermatheca    92.3 Adult Ovary    443.1 Adult Testis    210.6 Adult Male Accessory Gland no informative data Adult Carcass    106.2 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland no informative data Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut no informative data Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland no informative data Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    118.4   NA  Eye    207.25   NA  Brain    157.2   150.075  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    160.1   NA  Crop    142.8   47.9  Midgut    no informative data   85  Hindgut    104   98.6  Malpighian Tubules    83.6   87.7  Fat Body    82.4   no informative data  Salivary Gland    no informative data   NA  Heart    131.875   152.475  Trachea    NA   NA  VirginFemale Spermatheca    92.5   NA  InseminatedFemale Spermatheca    92.3   NA  Ovary    443.1   NA  Testis    210.6   NA  Male Accessory Gland    no informative data   83.375  Carcass    106.2 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_01
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038251 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3508-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4pnr-MD237 CG3508GD10991 lethal | pupal stage, with Scer\GAL4pnr-MD237 CG3508GD10991 viable CG3508e03375 CG3508EY14285 CG3508EY16325 Sterility Allele fertile CG3508e03375 CG3508EY14285 CG3508EY16325 Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of CG3508 Class Mutagen Stocks Known lesion CG3508e03375 piggyBac transposase 2 -- CG3508EY14285 P-element activity 1 -- CG3508EY16325 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG3508 Class Mutagen Stocks Known lesion CG3508GD10991 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG3508HMS00687 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG3508KK104531 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel8160 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD10991} NA P{KK104531} NA P{TRiP.HMS00687} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}CG3508EY14285 NA P{EPgy2}CG3508EY16325 NA miscellaneous insertions PBac{RB}CG3508e03375 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG3508 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 66852 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0038251 DroID - A comprehensive database of gene and protein interactions. • FBgn0038251 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41778
Orthologs
Genome-wide drosophilid orthologs	Dana\GF17451 Dere\GG16869 Dgri\GH18660 Dmoj\GI10685 Dper\GL24417 Dpse\GA17490 Dsec\GM24178 Dsim\GD18971 Dvir\GJ24355 Dwil\GK12813 Dyak\GE24250
Curated drosophilid orthologs	Dpse\GA17490
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL013291-PA Aedes aegypti (mosquito) AGAP002875-PA Anopheles gambiae (mosquito) XP_001121823.1 Apis mellifera (honey bee) BGIBMGA005043-PA Bombyx mori (silk worm) ENSBTAP00000034708 Bos taurus (bovine) ENSCAFP00000032853 Canis familiaris (dog) ENSCINP00000014561 Ciona intestinalis (sea squirt) CPIJ002766 Culex pipens (mosquito) 220611 Capitella spl (polychaete worm) ENSECAP00000015902 Equus caballus (horse) ENSP00000302276 Homo sapiens (human) 128589 Lottia gigantea (owl limpet) ENSMODP00000032615 Monodelphis domestica (gray opossum) ENSMMUP00000000967 Macaca mulatta (rhesus monkey) ENSMUSP00000102652 Mus musculus (house mouse) PHUM009824-PA Pediculus humanus (human body louse) ENSPPYP00000009338 Pongo pygmaeus (orangutan) ENSPTRP00000015808 Pan troglodytes (chimpanzee) ENSRNOP00000052039 Rattus norvegicus (norway rat) XP_971813.1 Tribolium castaneum (red flour beetle) ENSTNIP00000000136 Tetraodon nigroviridis (green spotted pufferfish) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV11295 LH12348 ISCW010097 FBgn0241379 FBgn0214822 FBgn0211435 FBgn0190480 FBgn0179042 FBgn0077501 FBgn0162006 FBgn0133449 FBgn0126127 FBgn0109097 FBgn0094469 CPIJ002766 BGIBMGA005043 ACYPI001117 GB17243 AGAP002875 PB23205 PHUM450560 GLEAN_09262
Stocks & Reagents
Stocks Listed in FlyBase ( 8 )
Bloomington	18151 w1118; PBac{RB}CG3508e03375 20799 y1 w67c23; P{EPgy2}CG3508EY14285 21200 y1 w67c23; P{EPgy2}CG3508EY16325 32898 y1 sc* v1; P{TRiP.HMS00687}attP2
Harvard	- PBac{RB}CG3508e03375
VDRC	v100500 P{KK104531}VIE-260B v34632 w1118; P{GD10991}v34632 v34633 w1118; P{GD10991}v34633/CyO
Genomic Clones ( 1 )
	BACR45M03 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 117 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD30520 RE11603
Other clones	DPiM_LD30520
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH20838 LD05551 LD05961 LD06191 LD08262 LD42990 LP13574 RE01773 RE02021 RE08892 RE10151 RE15204 RE61195 RE69285 RE72316 RE74628 RH18233 RH19711 RH19755 RH42557 SD07443
Other clones	Dmel_neb_015929_0897_2255 RH09369 RP003006503 RP003020291 RP003025719 RP003028457 RP003046419 RP003057060 RP003077827 RP003078421 RP003091005 RP003098445 RP003098472 RP003101659 RP003105884 RP003107073 RP003107087 RP003111417 RP003113657 RP003126006 RP003129031 RP003133022 RP003141982 RP003145302 RP003149276 RP003157811 RP003158411 RP003164928 RP003166087 RP003168878 RP003172087 RP003175376 RP003183299 RP003188412 RP003188838 RP003196883 RP003198558 RP003201467 RP003207778 RP003209480 RP003227423 RP003232602 RP003235812 RP003243038 RP003245579 RP003248352 RP003248750 RP003257424 RP003259769 RP003261945 RP003274475 RP003276392 RP003277875 RP003288142 RP003301741 RP003304031 RP003315931 RP003319197 RP003321006 RP003321936 RP003327628 RP003331071 RP003334513 RP003351942 RP003357677 RP003389997 RP003407930 RP003408891 RP003415739 RP003416554 RP003417894 RP003419167 RP003427349 RP003431424 RP003475695 RP003488200 RP003490919 RP003494354 RP003497179 RP003497488 RP003497945 RP003516875 RP003550319 RP003577686 RP003585090 RP003588345 RP003615782 RP003619036 RP003620275 RP003647276 RP003657291 RP003662348 RP003681050
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0038251 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41778
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_142124 NM_169595 RefSeq (Proteins) • NP_650381 NP_731932 DDBJ / EMBL / GenBank • AA950637 AAF55085 AAK93210 AAN13614 AAN71306 AW943035 AY051786 BI170214 BT001551 CL868623 Entrez Gene - A searchable database of RefSeq genes. • 41778 UniProtKB/TrEMBL • Q8IGW8 Q8INF6 Q9VFH2
Other Crossreferences
Linkouts
	BioGRID - A database of protein and genetic interactions • 66852 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0038251 DroID - A comprehensive database of gene and protein interactions. • FBgn0038251 DRSC - Results from RNAi screens. • FBgn0038251 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038251 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3508-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0038251 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41778 InParanoid A subset of ortholog calls from InParanoid. • AAEL013291-PA Aedes aegypti (mosquito) AGAP002875-PA Anopheles gambiae (mosquito) XP_001121823.1 Apis mellifera (honey bee) BGIBMGA005043-PA Bombyx mori (silk worm) ENSBTAP00000034708 Bos taurus (bovine) ENSCAFP00000032853 Canis familiaris (dog) ENSCINP00000014561 Ciona intestinalis (sea squirt) CPIJ002766 Culex pipens (mosquito) 220611 Capitella spl (polychaete worm) ENSECAP00000015902 Equus caballus (horse) ENSP00000302276 Homo sapiens (human) 128589 Lottia gigantea (owl limpet) ENSMODP00000032615 Monodelphis domestica (gray opossum) ENSMMUP00000000967 Macaca mulatta (rhesus monkey) ENSMUSP00000102652 Mus musculus (house mouse) PHUM009824-PA Pediculus humanus (human body louse) ENSPPYP00000009338 Pongo pygmaeus (orangutan) ENSPTRP00000015808 Pan troglodytes (chimpanzee) ENSRNOP00000052039 Rattus norvegicus (norway rat) XP_971813.1 Tribolium castaneum (red flour beetle) ENSTNIP00000000136 Tetraodon nigroviridis (green spotted pufferfish) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41778 modMine - Data generated by the modENCODE project. • FBgn0038251 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV11295 LH12348 ISCW010097 FBgn0241379 FBgn0214822 FBgn0211435 FBgn0190480 FBgn0179042 FBgn0077501 FBgn0162006 FBgn0133449 FBgn0126127 FBgn0109097 FBgn0094469 CPIJ002766 BGIBMGA005043 ACYPI001117 GB17243 AGAP002875 PB23205 PHUM450560 GLEAN_09262
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG3508 (Keleman et al., 2009.8.5, Ni et al., 2010.12.1)
Name Synonym
Secondary FlyBase IDs
References ( 11 )
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Ni et al., 2010.12.1, A genome-scale shRNA resource for transgenic RNAi in Drosophila. A genome-scale shRNA resource for transgenic RNAi in Drosophila. [FBrf0212437] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]