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Gene Dmel\CG5516

General Information
Symbol	Dmel\CG5516	Species	D. melanogaster
Name		Annotation symbol	CG5516
Feature type	protein_coding_gene	FlyBase ID	FBgn0038389
Gene Model Status	Current	Stock availability	8 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	89A8-89A8	Sequence location	3R:11,789,589..11,790,483 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG5516 (FBgn0038389). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding; nucleic acid binding. The biological processes in which it is involved are not known. 5 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Zinc finger, CCHC retroviral-type; Zinc finger, CCHC-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, larval fat body, larval trachea, adult ovary, adult testis. Comments on Affy2 ProbeSet: ProbeSet 1626986_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG5516. Gene sequence location is 3R:11789589..11790483.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN32705 HFA15826
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 89A8-89A8   Limits computationally determined from genome sequence between P{PZ}blp01618 and P{PZ}gish04895&P{EP}EP3171
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG5516 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.43
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG5516-RA FBtr0083212  NM_142258   813   176 CG5516-RB FBtr0302549  NM_001202299   750   176
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG5516-PA   FBpp0082666   18.9   176   9.48     NP_650515   AAF55257 CG5516-PB   FBpp0291705   18.9   176   9.48     NP_001189228   ADV37319
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, CCHC-type (IPR001878) Zinc finger, CCHC retroviral-type (IPR013084)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF55257   AE014297 ADV37319   AY071154 AAL48776   BI213091   BP554629   CO179581   CO279272   CO287512   CO287866   CO287955   CO287958   CZ479787   EC072758   EC218942   EC229984   EC230560   GH758691   GH771596   GH781872   GH790034   GH791920   GH791921   GH794596   GH799933   GH807455   GH809827   GH817024   GH817453   GH824909   GH826008   GH827009   GH827190   GH828228   GH830134   GH837175   GH851678   GH851935   GH854801   GH858011   GH899629   GH901294   GH905594   GH911157   GH916342   GH921640   GH926109
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VF05
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0038389    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0038389 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0038389 expression level Developmental Stage   Expression Level embryo 00-02hr    2921 embryo 02-04hr    3435 embryo 04-06hr    3850 embryo 06-08hr    2344 embryo 08-10hr    2188 embryo 10-12hr    2078 embryo 12-14hr    1325 embryo 14-16hr    831 embryo 16-18hr    838 embryo 18-20hr    448 embryo 20-22hr    705 embryo 22-24hr    706 larva L1    618 larva L2    1067 larva L3 12hr old    753 larva L3 puffstage 1-2    996 larva L3 puffstage 3-6    1276 larva L3 puffstage 7-9    1589 white prepupae new    1406 white prepupae 12hr    1769 white prepupae 24hr    2308 pupae 2d postWPP    2123 pupae 3d postWPP    949 pupae 4d postWPP    506 adult male 01day    1212 adult male 05day    1424 adult male 30day    1097 adult female 01day    774 adult female 05day    1624 adult female 30day    1722 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2921) embryo 02-04hr  (3435) embryo 04-06hr  (3850) embryo 06-08hr  (2344) embryo 08-10hr  (2188) embryo 10-12hr  (2078) embryo 12-14hr  (1325) embryo 14-16hr  (831) embryo 16-18hr  (838) embryo 18-20hr  (448) embryo 20-22hr  (705) embryo 22-24hr  (706) larva L1  (618) larva L2  (1067) larva L3 12hr old  (753) larva L3 puffstage 1-2  (996) larva L3 puffstage 3-6  (1276) larva L3 puffstage 7-9  (1589) white prepupae new  (1406) white prepupae 12hr  (1769) white prepupae 24hr  (2308) pupae 2d postWPP  (2123) pupae 3d postWPP  (949) pupae 4d postWPP  (506) adult male 01day  (1212) adult male 05day  (1424) adult male 30day  (1097) adult female 01day  (774) adult female 05day  (1624) adult female 30day  (1722) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2921) embryo 02-04hr  (3435) embryo 04-06hr  (3850) embryo 06-08hr  (2344) embryo 08-10hr  (2188) embryo 10-12hr  (2078) embryo 12-14hr    1325 embryo 14-16hr    831 embryo 16-18hr    838 embryo 18-20hr    448 embryo 20-22hr    705 embryo 22-24hr    706 larva L1    618 larva L2    1067 larva L3 12hr old    753 larva L3 puffstage 1-2    996 larva L3 puffstage 3-6    1276 larva L3 puffstage 7-9  (1589) white prepupae new  1406 white prepupae 12hr  (1769) white prepupae 24hr  (2308) pupae 2d postWPP  (2123) pupae 3d postWPP    949 pupae 4d postWPP    506 adult male 01day    1212 adult male 05day  1424 adult male 30day    1097 adult female 01day    774 adult female 05day  (1624) adult female 30day  (1722) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2921 embryo 02-04hr    3435 embryo 04-06hr    3850 embryo 06-08hr    2344 embryo 08-10hr    2188 embryo 10-12hr    2078 embryo 12-14hr    1325 embryo 14-16hr    831 embryo 16-18hr    838 embryo 18-20hr    448 embryo 20-22hr    705 embryo 22-24hr    706 larva L1    618 larva L2    1067 larva L3 12hr old    753 larva L3 puffstage 1-2    996 larva L3 puffstage 3-6    1276 larva L3 puffstage 7-9    1589 white prepupae new    1406 white prepupae 12hr    1769 white prepupae 24hr    2308 pupae 2d postWPP    2123 pupae 3d postWPP    949 pupae 4d postWPP    506 adult male 01day    1212 adult male 05day    1424 adult male 30day    1097 adult female 01day    774 adult female 05day    1624 adult female 30day    1722 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2921 embryo 02-04hr    3435 embryo 04-06hr    3850 embryo 06-08hr    2344 embryo 08-10hr    2188 embryo 10-12hr    2078 embryo 12-14hr    1325 embryo 14-16hr    831 embryo 16-18hr    838 embryo 18-20hr    448 embryo 20-22hr    705 embryo 22-24hr    706 larva L1    618 larva L2    1067 larva L3 12hr old    753 larva L3 puffstage 1-2    996 larva L3 puffstage 3-6    1276 larva L3 puffstage 7-9    1589 white prepupae new    1406 white prepupae 12hr    1769 white prepupae 24hr    2308 pupae 2d postWPP    2123 pupae 3d postWPP    949 pupae 4d postWPP    506 adult male 01day    1212 adult male 05day    1424 adult male 30day    1097 adult female 01day    774 adult female 05day    1624 adult female 30day    1722 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0038389 expression level Developmental Stage   Expression Level embryo 00-02hr    2921 embryo 02-04hr    3435 embryo 04-06hr    3850 embryo 06-08hr    2344 embryo 08-10hr    2188 embryo 10-12hr    2078 embryo 12-14hr    1325 embryo 14-16hr    831 embryo 16-18hr    838 embryo 18-20hr    448 embryo 20-22hr    705 embryo 22-24hr    706 larva L1    618 larva L2    1067 larva L3 12hr old    753 larva L3 puffstage 1-2    996 larva L3 puffstage 3-6    1276 larva L3 puffstage 7-9    1589 white prepupae new    1406 white prepupae 12hr    1769 white prepupae 24hr    2308 pupae 2d postWPP    2123 pupae 3d postWPP    949 pupae 4d postWPP    506 adult male 01day    1212 adult male 05day    1424 adult male 30day    1097 adult female 01day    774 adult female 05day    1624 adult female 30day    1722 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2921) embryo 02-04hr  (3435) embryo 04-06hr  (3850) embryo 06-08hr  (2344) embryo 08-10hr  (2188) embryo 10-12hr  (2078) embryo 12-14hr  (1325) embryo 14-16hr  (831) embryo 16-18hr  (838) embryo 18-20hr  (448) embryo 20-22hr  (705) embryo 22-24hr  (706) larva L1  (618) larva L2  (1067) larva L3 12hr old  (753) larva L3 puffstage 1-2  (996) larva L3 puffstage 3-6  (1276) larva L3 puffstage 7-9  (1589) white prepupae new  (1406) white prepupae 12hr  (1769) white prepupae 24hr  (2308) pupae 2d postWPP  (2123) pupae 3d postWPP  (949) pupae 4d postWPP  (506) adult male 01day  (1212) adult male 05day  (1424) adult male 30day  (1097) adult female 01day  (774) adult female 05day  (1624) adult female 30day  (1722) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2921) embryo 02-04hr  (3435) embryo 04-06hr  (3850) embryo 06-08hr  2344 embryo 08-10hr  2188 embryo 10-12hr  2078 embryo 12-14hr    1325 embryo 14-16hr    831 embryo 16-18hr    838 embryo 18-20hr    448 embryo 20-22hr    705 embryo 22-24hr    706 larva L1    618 larva L2    1067 larva L3 12hr old    753 larva L3 puffstage 1-2    996 larva L3 puffstage 3-6    1276 larva L3 puffstage 7-9  1589 white prepupae new  1406 white prepupae 12hr  1769 white prepupae 24hr  2308 pupae 2d postWPP  2123 pupae 3d postWPP    949 pupae 4d postWPP    506 adult male 01day    1212 adult male 05day  1424 adult male 30day    1097 adult female 01day    774 adult female 05day  1624 adult female 30day  1722 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2921 embryo 02-04hr    3435 embryo 04-06hr    3850 embryo 06-08hr    2344 embryo 08-10hr    2188 embryo 10-12hr    2078 embryo 12-14hr    1325 embryo 14-16hr    831 embryo 16-18hr    838 embryo 18-20hr    448 embryo 20-22hr    705 embryo 22-24hr    706 larva L1    618 larva L2    1067 larva L3 12hr old    753 larva L3 puffstage 1-2    996 larva L3 puffstage 3-6    1276 larva L3 puffstage 7-9    1589 white prepupae new    1406 white prepupae 12hr    1769 white prepupae 24hr    2308 pupae 2d postWPP    2123 pupae 3d postWPP    949 pupae 4d postWPP    506 adult male 01day    1212 adult male 05day    1424 adult male 30day    1097 adult female 01day    774 adult female 05day    1624 adult female 30day    1722 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2921 embryo 02-04hr    3435 embryo 04-06hr    3850 embryo 06-08hr    2344 embryo 08-10hr    2188 embryo 10-12hr    2078 embryo 12-14hr    1325 embryo 14-16hr    831 embryo 16-18hr    838 embryo 18-20hr    448 embryo 20-22hr    705 embryo 22-24hr    706 larva L1    618 larva L2    1067 larva L3 12hr old    753 larva L3 puffstage 1-2    996 larva L3 puffstage 3-6    1276 larva L3 puffstage 7-9    1589 white prepupae new    1406 white prepupae 12hr    1769 white prepupae 24hr    2308 pupae 2d postWPP    2123 pupae 3d postWPP    949 pupae 4d postWPP    506 adult male 01day    1212 adult male 05day    1424 adult male 30day    1097 adult female 01day    774 adult female 05day    1624 adult female 30day    1722 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0038389    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0038389 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, larval fat body, larval trachea, adult ovary, adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0038389 expression level Tissue   Expression Level Larval Central Nervous System    173.8 Larval Midgut    46.2 Larval Hindgut    62.9 Larval Malpighian Tubules    79.5 Larval Fat Body    104.9 Larval Salivary Gland    95 Larval Trachea    150.1 Larval Carcass    63.95 Adult Head    93.9 Adult Eye    163.425 Adult Brain    144.5 Adult Thoracic-Abdominal Ganglion    104.3 Adult Crop    78.5 Adult Midgut    56.7 Adult Hindgut    72.4 Adult Malpighian Tubules no informative data Adult Fat Body    57.2 Adult Salivary Gland    54.3 Adult Heart    84.8 Adult VirginFemale Spermatheca    35.2 Adult InseminatedFemale Spermatheca    40.4 Adult Ovary    236.5 Adult Testis    126.4 Adult Male Accessory Gland    99.3 Adult Carcass    56.4 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    173.8 Larval Midgut    46.2 Larval Hindgut    62.9 Larval Malpighian Tubules    79.5 Larval Fat Body    104.9 Larval Salivary Gland    95 Larval Trachea    150.1 Larval Carcass    63.95 Adult Head    93.9 Adult Eye    163.425 Adult Brain    144.5 Adult Thoracic-Abdominal Ganglion    104.3 Adult Crop    78.5 Adult Midgut    56.7 Adult Hindgut    72.4 Adult Malpighian Tubules no informative data Adult Fat Body    57.2 Adult Salivary Gland    54.3 Adult Heart    84.8 Adult VirginFemale Spermatheca    35.2 Adult InseminatedFemale Spermatheca    40.4 Adult Ovary    236.5 Adult Testis    126.4 Adult Male Accessory Gland    99.3 Adult Carcass    56.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    173.8 Larval Midgut    46.2 Larval Hindgut    62.9 Larval Malpighian Tubules    79.5 Larval Fat Body    104.9 Larval Salivary Gland    95 Larval Trachea    150.1 Larval Carcass    63.95 Adult Head    93.9 Adult Eye    163.425 Adult Brain    144.5 Adult Thoracic-Abdominal Ganglion    104.3 Adult Crop    78.5 Adult Midgut    56.7 Adult Hindgut    72.4 Adult Malpighian Tubules no informative data Adult Fat Body    57.2 Adult Salivary Gland    54.3 Adult Heart    84.8 Adult VirginFemale Spermatheca    35.2 Adult InseminatedFemale Spermatheca    40.4 Adult Ovary    236.5 Adult Testis    126.4 Adult Male Accessory Gland    99.3 Adult Carcass    56.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    173.8 Larval Midgut    46.2 Larval Hindgut    62.9 Larval Malpighian Tubules    79.5 Larval Fat Body    104.9 Larval Salivary Gland    95 Larval Trachea    150.1 Larval Carcass    63.95 Adult Head    93.9 Adult Eye    163.425 Adult Brain    144.5 Adult Thoracic-Abdominal Ganglion    104.3 Adult Crop    78.5 Adult Midgut    56.7 Adult Hindgut    72.4 Adult Malpighian Tubules no informative data Adult Fat Body    57.2 Adult Salivary Gland    54.3 Adult Heart    84.8 Adult VirginFemale Spermatheca    35.2 Adult InseminatedFemale Spermatheca    40.4 Adult Ovary    236.5 Adult Testis    126.4 Adult Male Accessory Gland    99.3 Adult Carcass    56.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0038389 expression level Tissue   Expression Level Larval Central Nervous System    173.8 Larval Midgut    46.2 Larval Hindgut    62.9 Larval Malpighian Tubules    79.5 Larval Fat Body    104.9 Larval Salivary Gland    95 Larval Trachea    150.1 Larval Carcass    63.95 Adult Head    93.9 Adult Eye    163.425 Adult Brain    144.5 Adult Thoracic-Abdominal Ganglion    104.3 Adult Crop    78.5 Adult Midgut    56.7 Adult Hindgut    72.4 Adult Malpighian Tubules no informative data Adult Fat Body    57.2 Adult Salivary Gland    54.3 Adult Heart    84.8 Adult VirginFemale Spermatheca    35.2 Adult InseminatedFemale Spermatheca    40.4 Adult Ovary    236.5 Adult Testis    126.4 Adult Male Accessory Gland    99.3 Adult Carcass    56.4 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    173.8 Larval Midgut    46.2 Larval Hindgut    62.9 Larval Malpighian Tubules    79.5 Larval Fat Body    104.9 Larval Salivary Gland    95 Larval Trachea    150.1 Larval Carcass    63.95 Adult Head    93.9 Adult Eye    163.425 Adult Brain    144.5 Adult Thoracic-Abdominal Ganglion    104.3 Adult Crop    78.5 Adult Midgut    56.7 Adult Hindgut    72.4 Adult Malpighian Tubules no informative data Adult Fat Body    57.2 Adult Salivary Gland    54.3 Adult Heart    84.8 Adult VirginFemale Spermatheca    35.2 Adult InseminatedFemale Spermatheca    40.4 Adult Ovary    236.5 Adult Testis    126.4 Adult Male Accessory Gland    99.3 Adult Carcass    56.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    173.8 Larval Midgut    46.2 Larval Hindgut    62.9 Larval Malpighian Tubules    79.5 Larval Fat Body    104.9 Larval Salivary Gland    95 Larval Trachea    150.1 Larval Carcass    63.95 Adult Head    93.9 Adult Eye    163.425 Adult Brain    144.5 Adult Thoracic-Abdominal Ganglion    104.3 Adult Crop    78.5 Adult Midgut    56.7 Adult Hindgut    72.4 Adult Malpighian Tubules no informative data Adult Fat Body    57.2 Adult Salivary Gland    54.3 Adult Heart    84.8 Adult VirginFemale Spermatheca    35.2 Adult InseminatedFemale Spermatheca    40.4 Adult Ovary    236.5 Adult Testis    126.4 Adult Male Accessory Gland    99.3 Adult Carcass    56.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    173.8 Larval Midgut    46.2 Larval Hindgut    62.9 Larval Malpighian Tubules    79.5 Larval Fat Body    104.9 Larval Salivary Gland    95 Larval Trachea    150.1 Larval Carcass    63.95 Adult Head    93.9 Adult Eye    163.425 Adult Brain    144.5 Adult Thoracic-Abdominal Ganglion    104.3 Adult Crop    78.5 Adult Midgut    56.7 Adult Hindgut    72.4 Adult Malpighian Tubules no informative data Adult Fat Body    57.2 Adult Salivary Gland    54.3 Adult Heart    84.8 Adult VirginFemale Spermatheca    35.2 Adult InseminatedFemale Spermatheca    40.4 Adult Ovary    236.5 Adult Testis    126.4 Adult Male Accessory Gland    99.3 Adult Carcass    56.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules no informative data Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    93.9   NA  Eye    163.425   NA  Brain    144.5   173.8  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    104.3   NA  Crop    78.5   46.2  Midgut    56.7   62.9  Hindgut    72.4   79.5  Malpighian Tubules    no informative data   104.9  Fat Body    57.2   95  Salivary Gland    54.3   NA  Heart    84.8   150.1  Trachea    NA   NA  VirginFemale Spermatheca    35.2   NA  InseminatedFemale Spermatheca    40.4   NA  Ovary    236.5   NA  Testis    126.4   NA  Male Accessory Gland    99.3   63.95  Carcass    56.4 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_06
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038389 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5516-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG5516GD11679 Other Phenotypes Allele body color defective, with Scer\GAL4pnr-MD237 CG5516GD11679 visible, with Scer\GAL4pnr-MD237 CG5516GD11679 Phenotype manifest in Allele mesothoracic tergum, with Scer\GAL4pnr-MD237 CG5516GD11679 trichogen cell, with Scer\GAL4pnr-MD237 CG5516GD11679
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG5516 Class Mutagen Stocks Known lesion CG5516e01979 piggyBac transposase 1 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG5516 Class Mutagen Stocks Known lesion CG5516GD11679 in vitro construct - RNAi in vitro construct - regulatory fusion 6 Yes CG5516KK112705 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG5516tSa in vitro construct - genomic fragment 0 Yes CG5516tSb in vitro construct - genomic fragment 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel7327 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD11679} NA P{KK112705} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{RB}CG5516e01979 NA insertion of enhancer trap P{lacW}P16C3 No
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
nucleic acid binding inferred from electronic annotation with InterPro:IPR001878, InterPro:IPR013084 (FlyBase Curators et al., 2004-) zinc ion binding inferred from electronic annotation with InterPro:IPR001878, InterPro:IPR013084 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG5516 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 66994 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0038389 DroID - A comprehensive database of gene and protein interactions. • FBgn0038389 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41940
Orthologs
Genome-wide drosophilid orthologs	Dpse\GA18942
Curated drosophilid orthologs	Dpse\GA18942   Dsim\CG5516 (Swanson et al., 2001)
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AGAP004274-PA Anopheles gambiae (mosquito) XP_001944254.1 Acyrthosiphon pisum (pea aphid) At5g49400.1 Arabidopsis thaliana (wall cress) 123288 Branchiostoma floridae (lancelet) BGIBMGA008619-PA Bombyx mori (silk worm) ENSBTAP00000007079 Bos taurus (bovine) ENSCAFP00000033844 Canis familiaris (dog) cn03642 Cryptococcus neoformans (yeast-like fungus) CPIJ002557 Culex pipens (mosquito) ENSCPOP00000009719 Cavia porcellus (guinea pig) 150649 Chlamidomonas reinhardtii (green alga) DDB0191782 Dictyostelium discoideum (amoeba) 94039 Daphnia pulex (daphnia) ENSGACP00000027412 Gymnopilus aculeatus (mushroom) ENSGALP00000011547 Gallus gallus (chicken) ENSP00000347533 Homo sapiens (human) 234550 Lottia gigantea (owl limpet) ENSMODP00000017284 Monodelphis domestica (gray opossum) ENSMMUP00000023193 Macaca mulatta (rhesus monkey) ENSMUSP00000018383 Mus musculus (house mouse) XP_001603916.1 Nasonia vitripennis (wasp) ENSOANP00000011829 Ornithorynchus anatinus (platypus) ENSORLP00000001696 Oryzias latipes (japanese killifish) LOC_Os11g09310.1 Oryza sativa (asian rice) PHUM008528-PA Pediculus humanus (human body louse) 161790 Physcomitrella patens (moss) ENSPPYP00000017642 Pongo pygmaeus (orangutan) 564405 Populus trichocarpa (black cottonwood) ENSPTRP00000045563 Pan troglodytes (chimpanzee) ENSRNOP00000009098 Rattus norvegicus (norway rat) 5000912 Sorghum bicolor (sorghum) Smp_145010 Schistosoma mansoni (trematode parasite) XP_001192527.1 Strongylocentrotus purpuratus (purple sea urchin) XP_966939.1 Tribolium castaneum (red flour beetle) ENSTRUP00000020936 Takifugu rubripes (pufferfish Takifugu) 3706.m00101 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000009053 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16771 NV14879 LH13552 JGI_V11_299818 FBgn0078941 CPIJ002557 BGIBMGA008619 ACYPI001288 GB18428 AGAP004274 PHUM318530 GLEAN_10699
Stocks & Reagents
Stocks Listed in FlyBase ( 8 )
Harvard	- PBac{RB}CG5516e01979
VDRC	v103265 P{KK112705}VIE-260B v45562 w1118; P{GD11679}v45562 v45563 w1118; P{GD11679}v45563 v45564 w1118; P{GD11679}v45564 v51402 w1118; P{GD11679}v51402 v27449 w1118; P{GD11679}v27449/TM3 v45565 w1118; P{GD11679}v45565/TM3
Genomic Clones ( 1 )
	BACR04C07 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 43 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE18415
Other clones	DPiM_RE18415
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	20184 CK01.61D.E3 CK01.85A.D1 CK01.85A.E1 EK059908 EK066052 EK067007 EK067413 EK067417 EK133933 FGM230H06 RP003015699 RP003019113 RP003021045 RP003042652 RP003046846 RP003056319 RP003065954 RP003082296 RP003096609 RP003109341 RP003177865 RP003180667 RP003187872 RP003248487 RP003297040 RP003304286 RP003311309 RP003311541 RP003311568 RP003318467 RP003335690 RP003355261 RP003362510 RP003384107 RP003473225 RP003480095 RP003505710 RP003505752 RP003555250 RP003625575
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0038389 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41940
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_142258 NM_001202299 RefSeq (Proteins) • NP_650515 NP_001189228 DDBJ / EMBL / GenBank • AAF55257 AAL48776 ADV37319 AY071154 BI213091 CZ479787 Entrez Gene - A searchable database of RefSeq genes. • 41940 UniProtKB/TrEMBL • Q9VF05
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, CCHC-type (IPR001878) Zinc finger, CCHC retroviral-type (IPR013084)
Linkouts
	BioGRID - A database of protein and genetic interactions • 66994 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0038389 DroID - A comprehensive database of gene and protein interactions. • FBgn0038389 DRSC - Results from RNAi screens. • FBgn0038389 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038389 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5516-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0038389 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41940 InParanoid A subset of ortholog calls from InParanoid. • AGAP004274-PA Anopheles gambiae (mosquito) XP_001944254.1 Acyrthosiphon pisum (pea aphid) At5g49400.1 Arabidopsis thaliana (wall cress) 123288 Branchiostoma floridae (lancelet) BGIBMGA008619-PA Bombyx mori (silk worm) ENSBTAP00000007079 Bos taurus (bovine) ENSCAFP00000033844 Canis familiaris (dog) cn03642 Cryptococcus neoformans (yeast-like fungus) CPIJ002557 Culex pipens (mosquito) ENSCPOP00000009719 Cavia porcellus (guinea pig) 150649 Chlamidomonas reinhardtii (green alga) DDB0191782 Dictyostelium discoideum (amoeba) 94039 Daphnia pulex (daphnia) ENSGACP00000027412 Gymnopilus aculeatus (mushroom) ENSGALP00000011547 Gallus gallus (chicken) ENSP00000347533 Homo sapiens (human) 234550 Lottia gigantea (owl limpet) ENSMODP00000017284 Monodelphis domestica (gray opossum) ENSMMUP00000023193 Macaca mulatta (rhesus monkey) ENSMUSP00000018383 Mus musculus (house mouse) XP_001603916.1 Nasonia vitripennis (wasp) ENSOANP00000011829 Ornithorynchus anatinus (platypus) ENSORLP00000001696 Oryzias latipes (japanese killifish) LOC_Os11g09310.1 Oryza sativa (asian rice) PHUM008528-PA Pediculus humanus (human body louse) 161790 Physcomitrella patens (moss) ENSPPYP00000017642 Pongo pygmaeus (orangutan) 564405 Populus trichocarpa (black cottonwood) ENSPTRP00000045563 Pan troglodytes (chimpanzee) ENSRNOP00000009098 Rattus norvegicus (norway rat) 5000912 Sorghum bicolor (sorghum) Smp_145010 Schistosoma mansoni (trematode parasite) XP_001192527.1 Strongylocentrotus purpuratus (purple sea urchin) XP_966939.1 Tribolium castaneum (red flour beetle) ENSTRUP00000020936 Takifugu rubripes (pufferfish Takifugu) 3706.m00101 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000009053 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41940 modMine - Data generated by the modENCODE project. • FBgn0038389 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16771 NV14879 LH13552 JGI_V11_299818 FBgn0078941 CPIJ002557 BGIBMGA008619 ACYPI001288 GB18428 AGAP004274 PHUM318530 GLEAN_10699
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG5516 (Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 14 )
Research paper	Dottorini et al., 2011, BMC Bioinformatics 12: 34 Gepoclu: a software tool for identifying and analyzing gene positional clusters in large-scale gene expression analysis. [FBrf0214379]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452] Swanson et al., 2001, Proc. Natl. Acad. Sci. USA 98: Gene characteristics and dN/dS ratios of Drosophila simulans. [FBrf0137427]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Stevaux, 2002.3.12, Deletions in the CG4287 and CG5516 genes. Deletions in the CG4287 and CG5516 genes. [FBrf0146770]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]