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Gene Dmel\CG8925

General Information
Symbol	Dmel\CG8925	Species	D. melanogaster
Name		Annotation symbol	CG8925
Feature type	protein_coding_gene	FlyBase ID	FBgn0038404
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	89B6-89B6	Sequence location	3R:11,997,731..12,006,200 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG8925 (FBgn0038404). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: carnitine transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: transmembrane transport. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain; Major facilitator superfamily domain, general substrate transporter; Sugar transporter, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed during late larval stages, during late pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult midgut, adult salivary gland, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1629455_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG8925. Gene sequence location is 3R:11997731..12006200.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features HFA16457 HFA16455 BKN26998 HFA16456
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 89B6-89B6   Limits computationally determined from genome sequence between P{PZ}blp01618 and P{PZ}gish04895&P{EP}EP3171
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG8925 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG8925-RA FBtr0083253  NM_142269   2383   670 CG8925-RB FBtr0113241  NM_001104343   2191   606
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG8925-PA   FBpp0082707   74.1   670   6.50     NP_650526   AAF55282 CG8925-PB   FBpp0112153   66.8   606   6.89     NP_001097813   ABW08687
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Sugar transporter, conserved site (IPR005829) Major facilitator superfamily domain, general substrate transporter (IPR016196) Major facilitator superfamily (IPR011701) Major facilitator superfamily domain (IPR020846)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF55282   AE014297 ABW08687   BT022777   EC213137   EL873596   EL873597   EL873674   EL873675   EL873782   EL873783
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VEY1 Q4V579
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0038404    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0038404 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed during late larval stages, during late pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0038404 expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    2 embryo 06-08hr    11 embryo 08-10hr    18 embryo 10-12hr    113 embryo 12-14hr    214 embryo 14-16hr    236 embryo 16-18hr    505 embryo 18-20hr    696 embryo 20-22hr    466 embryo 22-24hr    453 larva L1    517 larva L2    287 larva L3 12hr old    254 larva L3 puffstage 1-2    278 larva L3 puffstage 3-6    733 larva L3 puffstage 7-9    1536 white prepupae new    747 white prepupae 12hr    167 white prepupae 24hr    52 pupae 2d postWPP    144 pupae 3d postWPP    902 pupae 4d postWPP    2359 adult male 01day    392 adult male 05day    414 adult male 30day    373 adult female 01day    279 adult female 05day    96 adult female 30day    104 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    2 embryo 06-08hr    11 embryo 08-10hr    18 embryo 10-12hr  (113) embryo 12-14hr  (214) embryo 14-16hr  (236) embryo 16-18hr  (505) embryo 18-20hr  (696) embryo 20-22hr  (466) embryo 22-24hr  (453) larva L1  (517) larva L2  (287) larva L3 12hr old  (254) larva L3 puffstage 1-2  (278) larva L3 puffstage 3-6  (733) larva L3 puffstage 7-9  (1536) white prepupae new  (747) white prepupae 12hr  (167) white prepupae 24hr    52 pupae 2d postWPP  (144) pupae 3d postWPP  (902) pupae 4d postWPP  (2359) adult male 01day  (392) adult male 05day  (414) adult male 30day  (373) adult female 01day  (279) adult female 05day    96 adult female 30day  104 Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    2 embryo 06-08hr    11 embryo 08-10hr    18 embryo 10-12hr    113 embryo 12-14hr    214 embryo 14-16hr    236 embryo 16-18hr    505 embryo 18-20hr    696 embryo 20-22hr    466 embryo 22-24hr    453 larva L1    517 larva L2    287 larva L3 12hr old    254 larva L3 puffstage 1-2    278 larva L3 puffstage 3-6    733 larva L3 puffstage 7-9  (1536) white prepupae new    747 white prepupae 12hr    167 white prepupae 24hr    52 pupae 2d postWPP    144 pupae 3d postWPP    902 pupae 4d postWPP  (2359) adult male 01day    392 adult male 05day    414 adult male 30day    373 adult female 01day    279 adult female 05day    96 adult female 30day    104 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    2 embryo 06-08hr    11 embryo 08-10hr    18 embryo 10-12hr    113 embryo 12-14hr    214 embryo 14-16hr    236 embryo 16-18hr    505 embryo 18-20hr    696 embryo 20-22hr    466 embryo 22-24hr    453 larva L1    517 larva L2    287 larva L3 12hr old    254 larva L3 puffstage 1-2    278 larva L3 puffstage 3-6    733 larva L3 puffstage 7-9    1536 white prepupae new    747 white prepupae 12hr    167 white prepupae 24hr    52 pupae 2d postWPP    144 pupae 3d postWPP    902 pupae 4d postWPP    2359 adult male 01day    392 adult male 05day    414 adult male 30day    373 adult female 01day    279 adult female 05day    96 adult female 30day    104 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    2 embryo 06-08hr    11 embryo 08-10hr    18 embryo 10-12hr    113 embryo 12-14hr    214 embryo 14-16hr    236 embryo 16-18hr    505 embryo 18-20hr    696 embryo 20-22hr    466 embryo 22-24hr    453 larva L1    517 larva L2    287 larva L3 12hr old    254 larva L3 puffstage 1-2    278 larva L3 puffstage 3-6    733 larva L3 puffstage 7-9    1536 white prepupae new    747 white prepupae 12hr    167 white prepupae 24hr    52 pupae 2d postWPP    144 pupae 3d postWPP    902 pupae 4d postWPP    2359 adult male 01day    392 adult male 05day    414 adult male 30day    373 adult female 01day    279 adult female 05day    96 adult female 30day    104 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0038404 expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    2 embryo 06-08hr    11 embryo 08-10hr    18 embryo 10-12hr    113 embryo 12-14hr    214 embryo 14-16hr    236 embryo 16-18hr    505 embryo 18-20hr    696 embryo 20-22hr    466 embryo 22-24hr    453 larva L1    517 larva L2    287 larva L3 12hr old    254 larva L3 puffstage 1-2    278 larva L3 puffstage 3-6    733 larva L3 puffstage 7-9    1536 white prepupae new    747 white prepupae 12hr    167 white prepupae 24hr    52 pupae 2d postWPP    144 pupae 3d postWPP    902 pupae 4d postWPP    2359 adult male 01day    392 adult male 05day    414 adult male 30day    373 adult female 01day    279 adult female 05day    96 adult female 30day    104 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    2 embryo 06-08hr    11 embryo 08-10hr    18 embryo 10-12hr  113 embryo 12-14hr  (214) embryo 14-16hr  (236) embryo 16-18hr  (505) embryo 18-20hr  (696) embryo 20-22hr  (466) embryo 22-24hr  (453) larva L1  (517) larva L2  (287) larva L3 12hr old  (254) larva L3 puffstage 1-2  (278) larva L3 puffstage 3-6  (733) larva L3 puffstage 7-9  (1536) white prepupae new  (747) white prepupae 12hr  (167) white prepupae 24hr    52 pupae 2d postWPP  (144) pupae 3d postWPP  (902) pupae 4d postWPP  (2359) adult male 01day  (392) adult male 05day  (414) adult male 30day  (373) adult female 01day  (279) adult female 05day    96 adult female 30day  104 Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    2 embryo 06-08hr    11 embryo 08-10hr    18 embryo 10-12hr    113 embryo 12-14hr    214 embryo 14-16hr    236 embryo 16-18hr    505 embryo 18-20hr    696 embryo 20-22hr    466 embryo 22-24hr    453 larva L1    517 larva L2    287 larva L3 12hr old    254 larva L3 puffstage 1-2    278 larva L3 puffstage 3-6    733 larva L3 puffstage 7-9  1536 white prepupae new    747 white prepupae 12hr    167 white prepupae 24hr    52 pupae 2d postWPP    144 pupae 3d postWPP    902 pupae 4d postWPP  2359 adult male 01day    392 adult male 05day    414 adult male 30day    373 adult female 01day    279 adult female 05day    96 adult female 30day    104 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    2 embryo 06-08hr    11 embryo 08-10hr    18 embryo 10-12hr    113 embryo 12-14hr    214 embryo 14-16hr    236 embryo 16-18hr    505 embryo 18-20hr    696 embryo 20-22hr    466 embryo 22-24hr    453 larva L1    517 larva L2    287 larva L3 12hr old    254 larva L3 puffstage 1-2    278 larva L3 puffstage 3-6    733 larva L3 puffstage 7-9    1536 white prepupae new    747 white prepupae 12hr    167 white prepupae 24hr    52 pupae 2d postWPP    144 pupae 3d postWPP    902 pupae 4d postWPP    2359 adult male 01day    392 adult male 05day    414 adult male 30day    373 adult female 01day    279 adult female 05day    96 adult female 30day    104 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    2 embryo 06-08hr    11 embryo 08-10hr    18 embryo 10-12hr    113 embryo 12-14hr    214 embryo 14-16hr    236 embryo 16-18hr    505 embryo 18-20hr    696 embryo 20-22hr    466 embryo 22-24hr    453 larva L1    517 larva L2    287 larva L3 12hr old    254 larva L3 puffstage 1-2    278 larva L3 puffstage 3-6    733 larva L3 puffstage 7-9    1536 white prepupae new    747 white prepupae 12hr    167 white prepupae 24hr    52 pupae 2d postWPP    144 pupae 3d postWPP    902 pupae 4d postWPP    2359 adult male 01day    392 adult male 05day    414 adult male 30day    373 adult female 01day    279 adult female 05day    96 adult female 30day    104 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0038404    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0038404 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult midgut, adult salivary gland, adult male accessory gland. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0038404 expression level Tissue   Expression Level Larval Central Nervous System    8.025 Larval Midgut    61.7 Larval Hindgut no informative data Larval Malpighian Tubules    9.2 Larval Fat Body    7 Larval Salivary Gland    35.9 Larval Trachea    44.05 Larval Carcass    83.25 Adult Head    36.1 Adult Eye    18.575 Adult Brain    9.6 Adult Thoracic-Abdominal Ganglion    8.7 Adult Crop no informative data Adult Midgut    226.3 Adult Hindgut    26 Adult Malpighian Tubules    8.7 Adult Fat Body no informative data Adult Salivary Gland    166.7 Adult Heart    8.1 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    4.4 Adult Testis    7.9 Adult Male Accessory Gland    116.3 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    8.025 Larval Midgut    61.7 Larval Hindgut no informative data Larval Malpighian Tubules    9.2 Larval Fat Body    7 Larval Salivary Gland    35.9 Larval Trachea    44.05 Larval Carcass    83.25 Adult Head    36.1 Adult Eye    18.575 Adult Brain    9.6 Adult Thoracic-Abdominal Ganglion    8.7 Adult Crop no informative data Adult Midgut    226.3 Adult Hindgut    26 Adult Malpighian Tubules    8.7 Adult Fat Body no informative data Adult Salivary Gland    166.7 Adult Heart    8.1 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    4.4 Adult Testis    7.9 Adult Male Accessory Gland    116.3 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    8.025 Larval Midgut    61.7 Larval Hindgut no informative data Larval Malpighian Tubules    9.2 Larval Fat Body    7 Larval Salivary Gland    35.9 Larval Trachea    44.05 Larval Carcass    83.25 Adult Head    36.1 Adult Eye    18.575 Adult Brain    9.6 Adult Thoracic-Abdominal Ganglion    8.7 Adult Crop no informative data Adult Midgut    226.3 Adult Hindgut    26 Adult Malpighian Tubules    8.7 Adult Fat Body no informative data Adult Salivary Gland    166.7 Adult Heart    8.1 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    4.4 Adult Testis    7.9 Adult Male Accessory Gland    116.3 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    8.025 Larval Midgut    61.7 Larval Hindgut no informative data Larval Malpighian Tubules    9.2 Larval Fat Body    7 Larval Salivary Gland    35.9 Larval Trachea    44.05 Larval Carcass    83.25 Adult Head    36.1 Adult Eye    18.575 Adult Brain    9.6 Adult Thoracic-Abdominal Ganglion    8.7 Adult Crop no informative data Adult Midgut    226.3 Adult Hindgut    26 Adult Malpighian Tubules    8.7 Adult Fat Body no informative data Adult Salivary Gland    166.7 Adult Heart    8.1 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    4.4 Adult Testis    7.9 Adult Male Accessory Gland    116.3 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0038404 expression level Tissue   Expression Level Larval Central Nervous System    8.025 Larval Midgut    61.7 Larval Hindgut no informative data Larval Malpighian Tubules    9.2 Larval Fat Body    7 Larval Salivary Gland    35.9 Larval Trachea    44.05 Larval Carcass    83.25 Adult Head    36.1 Adult Eye    18.575 Adult Brain    9.6 Adult Thoracic-Abdominal Ganglion    8.7 Adult Crop no informative data Adult Midgut    226.3 Adult Hindgut    26 Adult Malpighian Tubules    8.7 Adult Fat Body no informative data Adult Salivary Gland    166.7 Adult Heart    8.1 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    4.4 Adult Testis    7.9 Adult Male Accessory Gland    116.3 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    8.025 Larval Midgut    61.7 Larval Hindgut no informative data Larval Malpighian Tubules    9.2 Larval Fat Body    7 Larval Salivary Gland    35.9 Larval Trachea    44.05 Larval Carcass    83.25 Adult Head    36.1 Adult Eye    18.575 Adult Brain    9.6 Adult Thoracic-Abdominal Ganglion    8.7 Adult Crop no informative data Adult Midgut    226.3 Adult Hindgut    26 Adult Malpighian Tubules    8.7 Adult Fat Body no informative data Adult Salivary Gland    166.7 Adult Heart    8.1 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    4.4 Adult Testis    7.9 Adult Male Accessory Gland    116.3 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    8.025 Larval Midgut    61.7 Larval Hindgut no informative data Larval Malpighian Tubules    9.2 Larval Fat Body    7 Larval Salivary Gland    35.9 Larval Trachea    44.05 Larval Carcass    83.25 Adult Head    36.1 Adult Eye    18.575 Adult Brain    9.6 Adult Thoracic-Abdominal Ganglion    8.7 Adult Crop no informative data Adult Midgut    226.3 Adult Hindgut    26 Adult Malpighian Tubules    8.7 Adult Fat Body no informative data Adult Salivary Gland    166.7 Adult Heart    8.1 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    4.4 Adult Testis    7.9 Adult Male Accessory Gland    116.3 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    8.025 Larval Midgut    61.7 Larval Hindgut no informative data Larval Malpighian Tubules    9.2 Larval Fat Body    7 Larval Salivary Gland    35.9 Larval Trachea    44.05 Larval Carcass    83.25 Adult Head    36.1 Adult Eye    18.575 Adult Brain    9.6 Adult Thoracic-Abdominal Ganglion    8.7 Adult Crop no informative data Adult Midgut    226.3 Adult Hindgut    26 Adult Malpighian Tubules    8.7 Adult Fat Body no informative data Adult Salivary Gland    166.7 Adult Heart    8.1 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    4.4 Adult Testis    7.9 Adult Male Accessory Gland    116.3 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut no informative data Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop no informative data Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body no informative data Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    36.1   NA  Eye    18.575   NA  Brain    9.6   8.025  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    8.7   NA  Crop    no informative data   61.7  Midgut    226.3   no informative data  Hindgut    26   9.2  Malpighian Tubules    8.7   7  Fat Body    no informative data   35.9  Salivary Gland    166.7   NA  Heart    8.1   44.05  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    4.4   NA  Testis    7.9   NA  Male Accessory Gland    116.3   83.25  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_18
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038404 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8925-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG8925GD3645 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG8925 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG8925 Class Mutagen Stocks Known lesion CG8925GD3645 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG8925KK106998 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6268 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD3645} NA P{KK106998} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
carnitine transporter activity inferred from sequence or structural similarity with EMBL:AF111425 (FlyBase, 1992-)
Biological Process
CV term Evidence References
transmembrane transport inferred from electronic annotation with InterPro:IPR005829, InterPro:IPR011701 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR011701 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG8925 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 67014 DroID - A comprehensive database of gene and protein interactions. • FBgn0038404 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41963
Orthologs
Genome-wide drosophilid orthologs	Dana\GF16159 Dere\GG16984 Dgri\GH18769 Dmoj\GI22660 Dper\GL12226 Dpse\GA26233 Dsec\GM24289 Dsim\GD19078 Dvir\GJ23388 Dwil\GK13266 Dyak\GE24374
Curated drosophilid orthologs	Dpse\GA21413   Dsim\CG8925 (Swanson et al., 2001)
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL004464-PA Aedes aegypti (mosquito) AGAP003038-PA Anopheles gambiae (mosquito) CPIJ019487 Culex pipens (mosquito) 3707.m00170 Tetrahymena thermophila (ciliate protozoa) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0241495 FBgn0215275 FBgn0210489 FBgn0190585 FBgn0179153 FBgn0247607 FBgn0149833 FBgn0145388 FBgn0126236 FBgn0109212 FBgn0093181 CPIJ019487 AGAP003038 AAEL004464
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v101128 P{KK106998}VIE-260B v37461 w1118; P{GD3645}v37461
Genomic Clones ( 1 )
	BACR37I18 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 5 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	IP13966
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	81588 IP13666 IP13766 IP13866
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0038404 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41963
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_142269 NM_001104343 RefSeq (Proteins) • NP_650526 NP_001097813 DDBJ / EMBL / GenBank • AAF55282 ABW08687 Entrez Gene - A searchable database of RefSeq genes. • 41963 UniProtKB/TrEMBL • Q4V579 Q9VEY1
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Sugar transporter, conserved site (IPR005829) Major facilitator superfamily domain, general substrate transporter (IPR016196) Major facilitator superfamily (IPR011701) Major facilitator superfamily domain (IPR020846)
Linkouts
	BioGRID - A database of protein and genetic interactions • 67014 DroID - A comprehensive database of gene and protein interactions. • FBgn0038404 DRSC - Results from RNAi screens. • FBgn0038404 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038404 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8925-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0038404 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41963 InParanoid A subset of ortholog calls from InParanoid. • AAEL004464-PA Aedes aegypti (mosquito) AGAP003038-PA Anopheles gambiae (mosquito) CPIJ019487 Culex pipens (mosquito) 3707.m00170 Tetrahymena thermophila (ciliate protozoa) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41963 modMine - Data generated by the modENCODE project. • FBgn0038404 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0241495 FBgn0215275 FBgn0210489 FBgn0190585 FBgn0179153 FBgn0247607 FBgn0149833 FBgn0145388 FBgn0126236 FBgn0109212 FBgn0093181 CPIJ019487 AGAP003038 AAEL004464
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG8925 (Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 12 )
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452] Swanson et al., 2001, Proc. Natl. Acad. Sci. USA 98: Gene characteristics and dN/dS ratios of Drosophila simulans. [FBrf0137427]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]
Curated genome annotation	Ketchum, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126677]