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Gene Dmel\pad

General Information
Symbol	Dmel\pad	Species	D. melanogaster
Name	poils au dos	Annotation symbol	CG10309
Feature type	protein_coding_gene	FlyBase ID	FBgn0038418
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	89B13-89B13	Sequence location	3R:12,168,040..12,171,551 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene poils au dos is referred to in FlyBase by the symbol Dmel\pad (CG10309, FBgn0038418). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding; nucleic acid binding. There is experimental evidence that it is involved in the biological process: chaeta morphogenesis; negative regulation of transcription from RNA polymerase II promoter. 8 alleles are reported. The phenotypes of these alleles are annotated with: presutural bristle; leg; microchaeta. It has one annotated transcript and one annotated polypeptide. Protein features are: Zinc finger, AD-type; Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1635101_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of pad. Gene sequence location is 3R:12168040..12171551.
External Summaries
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features BKN24955 HFA14227 Controlled Vocabulary Terms negative regulation of transcription from RNA polymerase II promoter
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 89B13-89B13   Limits computationally determined from genome sequence between P{PZ}gish04895&P{EP}EP3171 and P{lacW}CSN5L4032
Experimentally Determined Cytological Location
Cytogenetic map Notes References 89B13-89D1   Cytological map position inferred from a combination of meiotic recombination, SNP mapping and deficiency mapping.   (Gibert et al., 2005)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\pad for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) pad-RB FBtr0301514  NM_142277   3276   924
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein pad-PB   FBpp0290729   100.3   924   10.26     NP_650534   AAF55301
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, C2H2 (IPR007087) Zinc finger, AD-type (IPR012934) Zinc finger, C2H2-type/integrase, DNA-binding (IPR013087) Zinc finger, C2H2-like (IPR015880)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF55301   BT022205   CO269420   CO278626   CO329137   CO331722   EC071270   EC233222   EC258361   EV584580
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VEW6
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0038418    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0038418 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0038418 expression level Developmental Stage   Expression Level embryo 00-02hr    1917 embryo 02-04hr    427 embryo 04-06hr    607 embryo 06-08hr    534 embryo 08-10hr    385 embryo 10-12hr    278 embryo 12-14hr    252 embryo 14-16hr    195 embryo 16-18hr    181 embryo 18-20hr    184 embryo 20-22hr    138 embryo 22-24hr    143 larva L1    176 larva L2    98 larva L3 12hr old    115 larva L3 puffstage 1-2    132 larva L3 puffstage 3-6    225 larva L3 puffstage 7-9    315 white prepupae new    282 white prepupae 12hr    352 white prepupae 24hr    353 pupae 2d postWPP    225 pupae 3d postWPP    133 pupae 4d postWPP    105 adult male 01day    154 adult male 05day    209 adult male 30day    186 adult female 01day    453 adult female 05day    961 adult female 30day    1038 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1917) embryo 02-04hr  (427) embryo 04-06hr  (607) embryo 06-08hr  (534) embryo 08-10hr  (385) embryo 10-12hr  (278) embryo 12-14hr  (252) embryo 14-16hr  (195) embryo 16-18hr  (181) embryo 18-20hr  (184) embryo 20-22hr  (138) embryo 22-24hr  (143) larva L1  (176) larva L2    98 larva L3 12hr old  (115) larva L3 puffstage 1-2  (132) larva L3 puffstage 3-6  (225) larva L3 puffstage 7-9  (315) white prepupae new  (282) white prepupae 12hr  (352) white prepupae 24hr  (353) pupae 2d postWPP  (225) pupae 3d postWPP  (133) pupae 4d postWPP  105 adult male 01day  (154) adult male 05day  (209) adult male 30day  (186) adult female 01day  (453) adult female 05day  (961) adult female 30day  (1038) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1917) embryo 02-04hr    427 embryo 04-06hr    607 embryo 06-08hr    534 embryo 08-10hr    385 embryo 10-12hr    278 embryo 12-14hr    252 embryo 14-16hr    195 embryo 16-18hr    181 embryo 18-20hr    184 embryo 20-22hr    138 embryo 22-24hr    143 larva L1    176 larva L2    98 larva L3 12hr old    115 larva L3 puffstage 1-2    132 larva L3 puffstage 3-6    225 larva L3 puffstage 7-9    315 white prepupae new    282 white prepupae 12hr    352 white prepupae 24hr    353 pupae 2d postWPP    225 pupae 3d postWPP    133 pupae 4d postWPP    105 adult male 01day    154 adult male 05day    209 adult male 30day    186 adult female 01day    453 adult female 05day    961 adult female 30day    1038 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1917 embryo 02-04hr    427 embryo 04-06hr    607 embryo 06-08hr    534 embryo 08-10hr    385 embryo 10-12hr    278 embryo 12-14hr    252 embryo 14-16hr    195 embryo 16-18hr    181 embryo 18-20hr    184 embryo 20-22hr    138 embryo 22-24hr    143 larva L1    176 larva L2    98 larva L3 12hr old    115 larva L3 puffstage 1-2    132 larva L3 puffstage 3-6    225 larva L3 puffstage 7-9    315 white prepupae new    282 white prepupae 12hr    352 white prepupae 24hr    353 pupae 2d postWPP    225 pupae 3d postWPP    133 pupae 4d postWPP    105 adult male 01day    154 adult male 05day    209 adult male 30day    186 adult female 01day    453 adult female 05day    961 adult female 30day    1038 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1917 embryo 02-04hr    427 embryo 04-06hr    607 embryo 06-08hr    534 embryo 08-10hr    385 embryo 10-12hr    278 embryo 12-14hr    252 embryo 14-16hr    195 embryo 16-18hr    181 embryo 18-20hr    184 embryo 20-22hr    138 embryo 22-24hr    143 larva L1    176 larva L2    98 larva L3 12hr old    115 larva L3 puffstage 1-2    132 larva L3 puffstage 3-6    225 larva L3 puffstage 7-9    315 white prepupae new    282 white prepupae 12hr    352 white prepupae 24hr    353 pupae 2d postWPP    225 pupae 3d postWPP    133 pupae 4d postWPP    105 adult male 01day    154 adult male 05day    209 adult male 30day    186 adult female 01day    453 adult female 05day    961 adult female 30day    1038 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0038418 expression level Developmental Stage   Expression Level embryo 00-02hr    1917 embryo 02-04hr    427 embryo 04-06hr    607 embryo 06-08hr    534 embryo 08-10hr    385 embryo 10-12hr    278 embryo 12-14hr    252 embryo 14-16hr    195 embryo 16-18hr    181 embryo 18-20hr    184 embryo 20-22hr    138 embryo 22-24hr    143 larva L1    176 larva L2    98 larva L3 12hr old    115 larva L3 puffstage 1-2    132 larva L3 puffstage 3-6    225 larva L3 puffstage 7-9    315 white prepupae new    282 white prepupae 12hr    352 white prepupae 24hr    353 pupae 2d postWPP    225 pupae 3d postWPP    133 pupae 4d postWPP    105 adult male 01day    154 adult male 05day    209 adult male 30day    186 adult female 01day    453 adult female 05day    961 adult female 30day    1038 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1917) embryo 02-04hr  (427) embryo 04-06hr  (607) embryo 06-08hr  (534) embryo 08-10hr  (385) embryo 10-12hr  (278) embryo 12-14hr  (252) embryo 14-16hr  (195) embryo 16-18hr  (181) embryo 18-20hr  (184) embryo 20-22hr  138 embryo 22-24hr  143 larva L1  (176) larva L2    98 larva L3 12hr old  115 larva L3 puffstage 1-2  132 larva L3 puffstage 3-6  (225) larva L3 puffstage 7-9  (315) white prepupae new  (282) white prepupae 12hr  (352) white prepupae 24hr  (353) pupae 2d postWPP  (225) pupae 3d postWPP  133 pupae 4d postWPP  105 adult male 01day  (154) adult male 05day  (209) adult male 30day  (186) adult female 01day  (453) adult female 05day  (961) adult female 30day  (1038) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  1917 embryo 02-04hr    427 embryo 04-06hr    607 embryo 06-08hr    534 embryo 08-10hr    385 embryo 10-12hr    278 embryo 12-14hr    252 embryo 14-16hr    195 embryo 16-18hr    181 embryo 18-20hr    184 embryo 20-22hr    138 embryo 22-24hr    143 larva L1    176 larva L2    98 larva L3 12hr old    115 larva L3 puffstage 1-2    132 larva L3 puffstage 3-6    225 larva L3 puffstage 7-9    315 white prepupae new    282 white prepupae 12hr    352 white prepupae 24hr    353 pupae 2d postWPP    225 pupae 3d postWPP    133 pupae 4d postWPP    105 adult male 01day    154 adult male 05day    209 adult male 30day    186 adult female 01day    453 adult female 05day    961 adult female 30day    1038 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1917 embryo 02-04hr    427 embryo 04-06hr    607 embryo 06-08hr    534 embryo 08-10hr    385 embryo 10-12hr    278 embryo 12-14hr    252 embryo 14-16hr    195 embryo 16-18hr    181 embryo 18-20hr    184 embryo 20-22hr    138 embryo 22-24hr    143 larva L1    176 larva L2    98 larva L3 12hr old    115 larva L3 puffstage 1-2    132 larva L3 puffstage 3-6    225 larva L3 puffstage 7-9    315 white prepupae new    282 white prepupae 12hr    352 white prepupae 24hr    353 pupae 2d postWPP    225 pupae 3d postWPP    133 pupae 4d postWPP    105 adult male 01day    154 adult male 05day    209 adult male 30day    186 adult female 01day    453 adult female 05day    961 adult female 30day    1038 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1917 embryo 02-04hr    427 embryo 04-06hr    607 embryo 06-08hr    534 embryo 08-10hr    385 embryo 10-12hr    278 embryo 12-14hr    252 embryo 14-16hr    195 embryo 16-18hr    181 embryo 18-20hr    184 embryo 20-22hr    138 embryo 22-24hr    143 larva L1    176 larva L2    98 larva L3 12hr old    115 larva L3 puffstage 1-2    132 larva L3 puffstage 3-6    225 larva L3 puffstage 7-9    315 white prepupae new    282 white prepupae 12hr    352 white prepupae 24hr    353 pupae 2d postWPP    225 pupae 3d postWPP    133 pupae 4d postWPP    105 adult male 01day    154 adult male 05day    209 adult male 30day    186 adult female 01day    453 adult female 05day    961 adult female 30day    1038 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0038418    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0038418 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0038418 expression level Tissue   Expression Level Larval Central Nervous System    39.525 Larval Midgut    5.5 Larval Hindgut    9.4 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland    17.5 Larval Trachea    12.7 Larval Carcass    9.85 Adult Head no informative data Adult Eye    9.65 Adult Brain    28.9 Adult Thoracic-Abdominal Ganglion    14.6 Adult Crop no informative data Adult Midgut no informative data Adult Hindgut    15.6 Adult Malpighian Tubules    8.2 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    9.075 Adult VirginFemale Spermatheca    8.7 Adult InseminatedFemale Spermatheca no informative data Adult Ovary    107.6 Adult Testis    17.4 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    39.525 Larval Midgut    5.5 Larval Hindgut    9.4 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland    17.5 Larval Trachea    12.7 Larval Carcass    9.85 Adult Head no informative data Adult Eye    9.65 Adult Brain    28.9 Adult Thoracic-Abdominal Ganglion    14.6 Adult Crop no informative data Adult Midgut no informative data Adult Hindgut    15.6 Adult Malpighian Tubules    8.2 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    9.075 Adult VirginFemale Spermatheca    8.7 Adult InseminatedFemale Spermatheca no informative data Adult Ovary    107.6 Adult Testis    17.4 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    39.525 Larval Midgut    5.5 Larval Hindgut    9.4 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland    17.5 Larval Trachea    12.7 Larval Carcass    9.85 Adult Head no informative data Adult Eye    9.65 Adult Brain    28.9 Adult Thoracic-Abdominal Ganglion    14.6 Adult Crop no informative data Adult Midgut no informative data Adult Hindgut    15.6 Adult Malpighian Tubules    8.2 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    9.075 Adult VirginFemale Spermatheca    8.7 Adult InseminatedFemale Spermatheca no informative data Adult Ovary    107.6 Adult Testis    17.4 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    39.525 Larval Midgut    5.5 Larval Hindgut    9.4 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland    17.5 Larval Trachea    12.7 Larval Carcass    9.85 Adult Head no informative data Adult Eye    9.65 Adult Brain    28.9 Adult Thoracic-Abdominal Ganglion    14.6 Adult Crop no informative data Adult Midgut no informative data Adult Hindgut    15.6 Adult Malpighian Tubules    8.2 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    9.075 Adult VirginFemale Spermatheca    8.7 Adult InseminatedFemale Spermatheca no informative data Adult Ovary    107.6 Adult Testis    17.4 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0038418 expression level Tissue   Expression Level Larval Central Nervous System    39.525 Larval Midgut    5.5 Larval Hindgut    9.4 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland    17.5 Larval Trachea    12.7 Larval Carcass    9.85 Adult Head no informative data Adult Eye    9.65 Adult Brain    28.9 Adult Thoracic-Abdominal Ganglion    14.6 Adult Crop no informative data Adult Midgut no informative data Adult Hindgut    15.6 Adult Malpighian Tubules    8.2 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    9.075 Adult VirginFemale Spermatheca    8.7 Adult InseminatedFemale Spermatheca no informative data Adult Ovary    107.6 Adult Testis    17.4 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    39.525 Larval Midgut    5.5 Larval Hindgut    9.4 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland    17.5 Larval Trachea    12.7 Larval Carcass    9.85 Adult Head no informative data Adult Eye    9.65 Adult Brain    28.9 Adult Thoracic-Abdominal Ganglion    14.6 Adult Crop no informative data Adult Midgut no informative data Adult Hindgut    15.6 Adult Malpighian Tubules    8.2 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    9.075 Adult VirginFemale Spermatheca    8.7 Adult InseminatedFemale Spermatheca no informative data Adult Ovary    107.6 Adult Testis    17.4 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    39.525 Larval Midgut    5.5 Larval Hindgut    9.4 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland    17.5 Larval Trachea    12.7 Larval Carcass    9.85 Adult Head no informative data Adult Eye    9.65 Adult Brain    28.9 Adult Thoracic-Abdominal Ganglion    14.6 Adult Crop no informative data Adult Midgut no informative data Adult Hindgut    15.6 Adult Malpighian Tubules    8.2 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    9.075 Adult VirginFemale Spermatheca    8.7 Adult InseminatedFemale Spermatheca no informative data Adult Ovary    107.6 Adult Testis    17.4 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    39.525 Larval Midgut    5.5 Larval Hindgut    9.4 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland    17.5 Larval Trachea    12.7 Larval Carcass    9.85 Adult Head no informative data Adult Eye    9.65 Adult Brain    28.9 Adult Thoracic-Abdominal Ganglion    14.6 Adult Crop no informative data Adult Midgut no informative data Adult Hindgut    15.6 Adult Malpighian Tubules    8.2 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    9.075 Adult VirginFemale Spermatheca    8.7 Adult InseminatedFemale Spermatheca no informative data Adult Ovary    107.6 Adult Testis    17.4 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head no informative data Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop no informative data Adult Midgut no informative data Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca no informative data Adult Ovary     Adult Testis     Adult Male Accessory Gland no informative data Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    no informative data   NA  Eye    9.65   NA  Brain    28.9   39.525  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    14.6   NA  Crop    no informative data   5.5  Midgut    no informative data   9.4  Hindgut    15.6   no informative data  Malpighian Tubules    8.2   no informative data  Fat Body    no informative data   17.5  Salivary Gland    no informative data   NA  Heart    9.075   12.7  Trachea    NA   NA  VirginFemale Spermatheca    8.7   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    107.6   NA  Testis    17.4   NA  Male Accessory Gland    no informative data   9.85  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_13
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038418 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10309-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pupal stage pad2 pad3 pad4 viable | recessive pad1 Sterility Allele fertile | recessive pad1 Phenotype manifest in Allele anterior scutellar bristle | female | supernumerary pad1 leg pad2 pad3 pad4 mesothoracic tergum & macrochaeta | ectopic pad1 pad2 pad3 pad4 mesothoracic tergum & macrochaeta | ectopic (with Df(3R)sbd26) pad1 mesothoracic tergum & macrochaeta | ectopic (with Tp(3;1)P115) pad1 mesothoracic tergum & microchaeta pad1 pad2 microchaeta pad3 pad4 posterior postalar bristle | female | supernumerary pad1 posterior supraalar bristle | female | supernumerary pad1 presutural bristle pad1 sensillum campaniformium & wing | supernumerary pad1
Classical Alleles ( 5 )
For All Classical Alleles Show
Allele of pad Class Mutagen Stocks Known lesion pad1 natural population 1 Yes padEY23329 P-element activity 1 -- pad2 Delta2-3 0 Yes pad3 Delta2-3 0 Yes pad4 Delta2-3 0 Yes
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of pad Class Mutagen Stocks Known lesion padJF02235 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes padKK103995 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes padGD6937 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6269 (Ryder, 2004.4.26) Df(3R)Exel7329 (Ryder, 2004.4.26) Df(3R)pad3 (Gibert et al., 2005) Df(3R)pad4 (Gibert et al., 2005) Df(3R)sbd26 (Gibert et al., 2005) Tp(3;1)P115 (Gibert et al., 2005)
Not disrupted in	Df(1)91B (Gibert et al., 2005) Df(1)115 (Gibert et al., 2005) In(1)ac3 (Gibert et al., 2005) In(1)sc4 (Gibert et al., 2005)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD6937} NA P{KK103995} NA P{TRiP.JF02235} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}padEY23329 NA
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
chaeta morphogenesis inferred from mutant phenotype (Gibert et al., 2005) negative regulation of transcription from RNA polymerase II promoter inferred from mutant phenotype (Gibert et al., 2005)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
nucleic acid binding inferred from electronic annotation with InterPro:IPR013087 (FlyBase Curators et al., 2004-) zinc ion binding inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR012934, InterPro:IPR015880 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
nucleus inferred from electronic annotation with InterPro:IPR012934 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions pad allele Gene References unspecified h (Gibert et al., 2005) put (Gibert et al., 2005) sc (Gibert et al., 2005) tkv (Gibert et al., 2005)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 67026 DroID - A comprehensive database of gene and protein interactions. • FBgn0038418 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41981
Orthologs
Genome-wide drosophilid orthologs	Dana\GF18492 Dere\GG16998 Dgri\GH19547 Dmoj\GI22947 Dper\GL21600 Dpse\GA10237 Dsec\GM15150 Dsim\GD19092 Dvir\GJ23725 Dwil\GK13775 Dyak\GE24391
Curated drosophilid orthologs	Dpse\GA10237
Linkouts	OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17794 NV10543 LH25571 FBgn0241511 FBgn0215783 FBgn0210822 FBgn0190599 FBgn0170070 FBgn0070295 FBgn0159193 FBgn0145674 FBgn0127012 FBgn0109226 FBgn0095510 CPIJ012234 CPIJ012233 ACYPI006795 ACYPI001131 GB11295 AGAP006758 AAEL011003 AAEL007630 AAEL007627 PHUM504490 GLEAN_15411
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	31944 y1 v1; P{TRiP.JF02235}attP2 22623 y1 w67c23; P{EPgy2}padEY23329 36532 P{neoFRT}82B ry506 pad1/TM3, Sb1
VDRC	v108173 P{KK103995}VIE-260B
Genomic Clones ( 2 )
	BACR01H23 BACR05P04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 9 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	IP01015
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	18684 214243.43 CK01.124B.G10 Dmel_dig_018530_0646_3586 EK094459 EK130612 EK292110 EK301502
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0038418 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41981
Antibody Information
Other Information
Discoverer
Etymology
	The name "poils au dos" is French for "hairy back" and refers to the ectopic bristle phenotype of pad mutants. (Gibert et al., 2005)
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: pad CG10309 (Gibert et al., 2005)
Source for database merge of
Additional comments
Other Comments
	pad may be a repressor of ac and sc. The target sequences of pad activity are confined to a 14kb region around sc. (Gibert et al., 2005)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_142277 RefSeq (Proteins) • NP_650534 DDBJ / EMBL / GenBank • AAF55301 Entrez Gene - A searchable database of RefSeq genes. • 41981 UniProtKB/TrEMBL • Q9VEW6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, C2H2 (IPR007087) Zinc finger, AD-type (IPR012934) Zinc finger, C2H2-type/integrase, DNA-binding (IPR013087) Zinc finger, C2H2-like (IPR015880)
Linkouts
	BioGRID - A database of protein and genetic interactions • 67026 DroID - A comprehensive database of gene and protein interactions. • FBgn0038418 DRSC - Results from RNAi screens. • FBgn0038418 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038418 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10309-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0038418 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41981 Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /hjmuller/poils-au-dos1.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41981 modMine - Data generated by the modENCODE project. • FBgn0038418 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17794 NV10543 LH25571 FBgn0241511 FBgn0215783 FBgn0210822 FBgn0190599 FBgn0170070 FBgn0070295 FBgn0159193 FBgn0145674 FBgn0127012 FBgn0109226 FBgn0095510 CPIJ012234 CPIJ012233 ACYPI006795 ACYPI001131 GB11295 AGAP006758 AAEL011003 AAEL007630 AAEL007627 PHUM504490 GLEAN_15411
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	CG10309 (Brody et al., 2002, Hoskins et al., 2005, Keleman et al., 2009.8.5, Perkins et al., 2009) pad
Name Synonym	poils au dos (Gibert et al., 2005, Munoz-Descalzo et al., 2007)
Secondary FlyBase IDs
References ( 15 )
Research paper	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Munoz-Descalzo et al., 2007, Dev. Genes Evol. 217(4): 289--298 Identification and analysis of cabut orthologs in invertebrates and vertebrates. [FBrf0201250] Gibert et al., 2005, Dev. Biol. 288(1): 194--205 A major bristle QTL from a selected population of Drosophila uncovers the zinc-finger transcription factor Poils-au-dos, a repressor of achaete-scute. [FBrf0190122] Hoskins et al., 2005, Nucleic Acids Res. 33(21): e185 Rapid and efficient cDNA library screening by self-ligation of inverse PCR products (SLIP). [FBrf0191341] Brody et al., 2002, Mech. Dev. 113(1): 41--59 Identification of novel Drosophila neural precursor genes using a differential embryonic head cDNA screen. [FBrf0147137]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Dietzl et al., 2007, Nature 448(7150): Supplementary Table 1. [FBrf0202579]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Perkins et al., 2009, Update to TRiP stock collection. Update to TRiP stock collection. [FBrf0208864] Bellen, 2006.8.3, MBBatch686_2.xml MBBatch686_2.xml [FBrf0191805] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]
Curated genome annotation	Li, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126682]