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Gene Dmel\CG16941

General Information
Symbol	Dmel\CG16941	Species	D. melanogaster
Name		Annotation symbol	CG16941
Feature type	protein_coding_gene	FlyBase ID	FBgn0038464
Gene Model Status	Current	Stock availability	4 publicly available
Also Known As	SF3a1
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	89E6-89E7	Sequence location	3R:12,825,106..12,828,077 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG16941 (FBgn0038464). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: RNA binding. There is experimental evidence that it is involved in the biological process: mitosis; mitotic spindle organization; regulation of alternative mRNA splicing, via spliceosome. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Pre-mRNA splicing factor PRP21-like protein; SWAP/Surp; Ubiquitin; Ubiquitin subgroup; Ubiquitin supergroup. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1639977_at partially aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG16941: 6 out of 14 probes fall into this exonic region. Gene sequence location is 3R:12825106..12828077.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 89E6-89E7   Limits computationally determined from genome sequence between P{EP}MESK4EP1015 and P{EP}CG5208EP562&P{EP}DadEP3196
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG16941 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.48
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG16941-RA FBtr0083374  NM_142326   2558   784
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG16941-PA   FBpp0082817   88.1   784   6.33     NP_650583   AAF55372
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • SWAP/Surp (IPR000061) Ubiquitin (IPR000626) Ubiquitin supergroup (IPR019955) Ubiquitin subgroup (IPR019956) Pre-mRNA splicing factor PRP21-like protein (IPR022030)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA538802   AA538854   AA801720   AA803010   AA940728   AA952166   AE014297 AAF55372   AI063629   AI401918   AI404747   AI513700   AY047530 AAK77262   BF489486   BF489988   BF490798   BF506097   BI171538   BI243874   BI353095   BI353387   BI356694   BI357216   BI363818   BI365381   BI369960   BI375836   BI481549   BI612432   CO178029   CO194666   CO275896   CO282185   CO319997   CO322661   CO327160   CO330372   CO333430   CO339637   CO339750   EC069065   EC071898   EC073511   EC090758   EC195083   EC197470   EC204892   EC218557   EC239131   EC246920   EC250004   EC255361   EC258941   EC259826   EV583818   GH941494   GH944743   GH947088   GH951638   GH953555   GH953898   GH955789   GH956358   GH956846   GH957566   GH960485   GH961248   GH962547   GH968768   GH971096   GH975244   GH975571   GH976343   GH978234   GH978287   GH978979   GH981644   GH982411   GH983553   GH983587   GH984136   GH984246
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VEP9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic brain   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) ventral nerve cord   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
catalytic step 2 spliceosome inferred from direct assay (Herold et al., 2009) precatalytic spliceosome inferred from direct assay (Herold et al., 2009)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    39.4 Larval Midgut    31 Larval Hindgut    46.4 Larval Malpighian Tubules    55.3 Larval Fat Body    32.8 Larval Salivary Gland    58.9 Larval Trachea    40.55 Larval Carcass    43.65 Adult Head    31.5 Adult Eye    30.15 Adult Brain    26 Adult Thoracic-Abdominal Ganglion    30 Adult Crop    30.9 Adult Midgut    23.9 Adult Hindgut    32.1 Adult Malpighian Tubules    41.7 Adult Fat Body    49.7 Adult Salivary Gland    33.4 Adult Heart    36.875 Adult VirginFemale Spermatheca    48.5 Adult InseminatedFemale Spermatheca    44.7 Adult Ovary    55.9 Adult Testis    21.8 Adult Male Accessory Gland    53.8 Adult Carcass    36 Expression Level Scale  None   Low  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    39.4 Larval Midgut    31 Larval Hindgut    46.4 Larval Malpighian Tubules    55.3 Larval Fat Body    32.8 Larval Salivary Gland    58.9 Larval Trachea    40.55 Larval Carcass    43.65 Adult Head    31.5 Adult Eye    30.15 Adult Brain    26 Adult Thoracic-Abdominal Ganglion    30 Adult Crop    30.9 Adult Midgut    23.9 Adult Hindgut    32.1 Adult Malpighian Tubules    41.7 Adult Fat Body    49.7 Adult Salivary Gland    33.4 Adult Heart    36.875 Adult VirginFemale Spermatheca    48.5 Adult InseminatedFemale Spermatheca    44.7 Adult Ovary    55.9 Adult Testis    21.8 Adult Male Accessory Gland    53.8 Adult Carcass    36 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    39.4 Larval Midgut    31 Larval Hindgut    46.4 Larval Malpighian Tubules    55.3 Larval Fat Body    32.8 Larval Salivary Gland    58.9 Larval Trachea    40.55 Larval Carcass    43.65 Adult Head    31.5 Adult Eye    30.15 Adult Brain    26 Adult Thoracic-Abdominal Ganglion    30 Adult Crop    30.9 Adult Midgut    23.9 Adult Hindgut    32.1 Adult Malpighian Tubules    41.7 Adult Fat Body    49.7 Adult Salivary Gland    33.4 Adult Heart    36.875 Adult VirginFemale Spermatheca    48.5 Adult InseminatedFemale Spermatheca    44.7 Adult Ovary    55.9 Adult Testis    21.8 Adult Male Accessory Gland    53.8 Adult Carcass    36 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    39.4 Larval Midgut    31 Larval Hindgut    46.4 Larval Malpighian Tubules    55.3 Larval Fat Body    32.8 Larval Salivary Gland    58.9 Larval Trachea    40.55 Larval Carcass    43.65 Adult Head    31.5 Adult Eye    30.15 Adult Brain    26 Adult Thoracic-Abdominal Ganglion    30 Adult Crop    30.9 Adult Midgut    23.9 Adult Hindgut    32.1 Adult Malpighian Tubules    41.7 Adult Fat Body    49.7 Adult Salivary Gland    33.4 Adult Heart    36.875 Adult VirginFemale Spermatheca    48.5 Adult InseminatedFemale Spermatheca    44.7 Adult Ovary    55.9 Adult Testis    21.8 Adult Male Accessory Gland    53.8 Adult Carcass    36 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    39.4 Larval Midgut    31 Larval Hindgut    46.4 Larval Malpighian Tubules    55.3 Larval Fat Body    32.8 Larval Salivary Gland    58.9 Larval Trachea    40.55 Larval Carcass    43.65 Adult Head    31.5 Adult Eye    30.15 Adult Brain    26 Adult Thoracic-Abdominal Ganglion    30 Adult Crop    30.9 Adult Midgut    23.9 Adult Hindgut    32.1 Adult Malpighian Tubules    41.7 Adult Fat Body    49.7 Adult Salivary Gland    33.4 Adult Heart    36.875 Adult VirginFemale Spermatheca    48.5 Adult InseminatedFemale Spermatheca    44.7 Adult Ovary    55.9 Adult Testis    21.8 Adult Male Accessory Gland    53.8 Adult Carcass    36 Expression Level Scale  None   Low  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    39.4 Larval Midgut    31 Larval Hindgut    46.4 Larval Malpighian Tubules    55.3 Larval Fat Body    32.8 Larval Salivary Gland    58.9 Larval Trachea    40.55 Larval Carcass    43.65 Adult Head    31.5 Adult Eye    30.15 Adult Brain    26 Adult Thoracic-Abdominal Ganglion    30 Adult Crop    30.9 Adult Midgut    23.9 Adult Hindgut    32.1 Adult Malpighian Tubules    41.7 Adult Fat Body    49.7 Adult Salivary Gland    33.4 Adult Heart    36.875 Adult VirginFemale Spermatheca    48.5 Adult InseminatedFemale Spermatheca    44.7 Adult Ovary    55.9 Adult Testis    21.8 Adult Male Accessory Gland    53.8 Adult Carcass    36 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    39.4 Larval Midgut    31 Larval Hindgut    46.4 Larval Malpighian Tubules    55.3 Larval Fat Body    32.8 Larval Salivary Gland    58.9 Larval Trachea    40.55 Larval Carcass    43.65 Adult Head    31.5 Adult Eye    30.15 Adult Brain    26 Adult Thoracic-Abdominal Ganglion    30 Adult Crop    30.9 Adult Midgut    23.9 Adult Hindgut    32.1 Adult Malpighian Tubules    41.7 Adult Fat Body    49.7 Adult Salivary Gland    33.4 Adult Heart    36.875 Adult VirginFemale Spermatheca    48.5 Adult InseminatedFemale Spermatheca    44.7 Adult Ovary    55.9 Adult Testis    21.8 Adult Male Accessory Gland    53.8 Adult Carcass    36 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    39.4 Larval Midgut    31 Larval Hindgut    46.4 Larval Malpighian Tubules    55.3 Larval Fat Body    32.8 Larval Salivary Gland    58.9 Larval Trachea    40.55 Larval Carcass    43.65 Adult Head    31.5 Adult Eye    30.15 Adult Brain    26 Adult Thoracic-Abdominal Ganglion    30 Adult Crop    30.9 Adult Midgut    23.9 Adult Hindgut    32.1 Adult Malpighian Tubules    41.7 Adult Fat Body    49.7 Adult Salivary Gland    33.4 Adult Heart    36.875 Adult VirginFemale Spermatheca    48.5 Adult InseminatedFemale Spermatheca    44.7 Adult Ovary    55.9 Adult Testis    21.8 Adult Male Accessory Gland    53.8 Adult Carcass    36 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    31.5   NA  Eye    30.15   NA  Brain    26   39.4  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    no informative data   NA  Crop    30.9   31  Midgut    no informative data   46.4  Hindgut    32.1   55.3  Malpighian Tubules    41.7   no informative data  Fat Body    49.7   58.9  Salivary Gland    no informative data   NA  Heart    36.875   40.55  Trachea    NA   NA  VirginFemale Spermatheca    48.5   NA  InseminatedFemale Spermatheca    44.7   NA  Ovary    55.9   NA  Testis    21.8   NA  Male Accessory Gland    53.8   43.65  Carcass    36 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    37 central nervous system, larvae L3    43 central nervous system, pupae P8    17 head, virgin 1-day female    6 head, virgin 4-day female    9 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    8 head, mated 20-day female    6 head, mated 1-day male    10 head, mated 4-day male    11 head, mated 20-day male    14 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    4 digestive system, 4-day adult    9 digestive system, 20-day adult    8 fat body, larvae L3 wandering    5 fat body, white prepupae    8 fat body, pupae P8    11 carcass, larvae L3 wandering    24 carcass, 1-day adult    4 carcass, 4-day adult    6 carcass, 20-day adult    7 ovary, virgin 4-day female    40 ovary, mated 4-day female    47 testis, mated 4-day male    15 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (37) central nervous system, larvae L3  (43) central nervous system, pupae P8    17 head, virgin 1-day female    6 head, virgin 4-day female    9 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    8 head, mated 20-day female    6 head, mated 1-day male    10 head, mated 4-day male    11 head, mated 20-day male    14 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    4 digestive system, 4-day adult    9 digestive system, 20-day adult    8 fat body, larvae L3 wandering    5 fat body, white prepupae    8 fat body, pupae P8    11 carcass, larvae L3 wandering    24 carcass, 1-day adult    4 carcass, 4-day adult    6 carcass, 20-day adult    7 ovary, virgin 4-day female  (40) ovary, mated 4-day female  (47) testis, mated 4-day male    15 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    37 central nervous system, larvae L3    43 central nervous system, pupae P8    17 head, virgin 1-day female    6 head, virgin 4-day female    9 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    8 head, mated 20-day female    6 head, mated 1-day male    10 head, mated 4-day male    11 head, mated 20-day male    14 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    4 digestive system, 4-day adult    9 digestive system, 20-day adult    8 fat body, larvae L3 wandering    5 fat body, white prepupae    8 fat body, pupae P8    11 carcass, larvae L3 wandering    24 carcass, 1-day adult    4 carcass, 4-day adult    6 carcass, 20-day adult    7 ovary, virgin 4-day female    40 ovary, mated 4-day female    47 testis, mated 4-day male    15 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    37 central nervous system, larvae L3    43 central nervous system, pupae P8    17 head, virgin 1-day female    6 head, virgin 4-day female    9 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    8 head, mated 20-day female    6 head, mated 1-day male    10 head, mated 4-day male    11 head, mated 20-day male    14 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    4 digestive system, 4-day adult    9 digestive system, 20-day adult    8 fat body, larvae L3 wandering    5 fat body, white prepupae    8 fat body, pupae P8    11 carcass, larvae L3 wandering    24 carcass, 1-day adult    4 carcass, 4-day adult    6 carcass, 20-day adult    7 ovary, virgin 4-day female    40 ovary, mated 4-day female    47 testis, mated 4-day male    15 accessory gland, mated 4-day male    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    37 central nervous system, larvae L3    43 central nervous system, pupae P8    17 head, virgin 1-day female    6 head, virgin 4-day female    9 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    8 head, mated 20-day female    6 head, mated 1-day male    10 head, mated 4-day male    11 head, mated 20-day male    14 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    4 digestive system, 4-day adult    9 digestive system, 20-day adult    8 fat body, larvae L3 wandering    5 fat body, white prepupae    8 fat body, pupae P8    11 carcass, larvae L3 wandering    24 carcass, 1-day adult    4 carcass, 4-day adult    6 carcass, 20-day adult    7 ovary, virgin 4-day female    40 ovary, mated 4-day female    47 testis, mated 4-day male    15 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (37) central nervous system, larvae L3  (43) central nervous system, pupae P8    17 head, virgin 1-day female    6 head, virgin 4-day female    9 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    8 head, mated 20-day female    6 head, mated 1-day male    10 head, mated 4-day male    11 head, mated 20-day male    14 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    4 digestive system, 4-day adult    9 digestive system, 20-day adult    8 fat body, larvae L3 wandering    5 fat body, white prepupae    8 fat body, pupae P8    11 carcass, larvae L3 wandering    24 carcass, 1-day adult    4 carcass, 4-day adult    6 carcass, 20-day adult    7 ovary, virgin 4-day female  (40) ovary, mated 4-day female  (47) testis, mated 4-day male    15 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    37 central nervous system, larvae L3    43 central nervous system, pupae P8    17 head, virgin 1-day female    6 head, virgin 4-day female    9 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    8 head, mated 20-day female    6 head, mated 1-day male    10 head, mated 4-day male    11 head, mated 20-day male    14 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    4 digestive system, 4-day adult    9 digestive system, 20-day adult    8 fat body, larvae L3 wandering    5 fat body, white prepupae    8 fat body, pupae P8    11 carcass, larvae L3 wandering    24 carcass, 1-day adult    4 carcass, 4-day adult    6 carcass, 20-day adult    7 ovary, virgin 4-day female    40 ovary, mated 4-day female    47 testis, mated 4-day male    15 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    37 central nervous system, larvae L3    43 central nervous system, pupae P8    17 head, virgin 1-day female    6 head, virgin 4-day female    9 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    8 head, mated 20-day female    6 head, mated 1-day male    10 head, mated 4-day male    11 head, mated 20-day male    14 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    4 digestive system, 4-day adult    9 digestive system, 20-day adult    8 fat body, larvae L3 wandering    5 fat body, white prepupae    8 fat body, pupae P8    11 carcass, larvae L3 wandering    24 carcass, 1-day adult    4 carcass, 4-day adult    6 carcass, 20-day adult    7 ovary, virgin 4-day female    40 ovary, mated 4-day female    47 testis, mated 4-day male    15 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    47 embryo 02-04hr    58 embryo 04-06hr    60 embryo 06-08hr    60 embryo 08-10hr    43 embryo 10-12hr    29 embryo 12-14hr    25 embryo 14-16hr    22 embryo 16-18hr    15 embryo 18-20hr    10 embryo 20-22hr    14 embryo 22-24hr    11 larva L1    16 larva L2    14 larva L3 12hr old    11 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    17 larva L3 puffstage 7-9    19 white prepupae new    20 white prepupae 12hr    22 white prepupae 24hr    29 pupae 2d postWPP    17 pupae 3d postWPP    8 pupae 4d postWPP    7 adult male 01day    9 adult male 05day    12 adult male 30day    13 adult female 01day    22 adult female 05day    32 adult female 30day    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (47) embryo 02-04hr  (58) embryo 04-06hr  (60) embryo 06-08hr  (60) embryo 08-10hr  (43) embryo 10-12hr  (29) embryo 12-14hr    25 embryo 14-16hr    22 embryo 16-18hr    15 embryo 18-20hr    10 embryo 20-22hr    14 embryo 22-24hr    11 larva L1    16 larva L2    14 larva L3 12hr old    11 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    17 larva L3 puffstage 7-9    19 white prepupae new    20 white prepupae 12hr    22 white prepupae 24hr  (29) pupae 2d postWPP    17 pupae 3d postWPP    8 pupae 4d postWPP    7 adult male 01day    9 adult male 05day    12 adult male 30day    13 adult female 01day    22 adult female 05day  (32) adult female 30day  (32) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    47 embryo 02-04hr    58 embryo 04-06hr    60 embryo 06-08hr    60 embryo 08-10hr    43 embryo 10-12hr    29 embryo 12-14hr    25 embryo 14-16hr    22 embryo 16-18hr    15 embryo 18-20hr    10 embryo 20-22hr    14 embryo 22-24hr    11 larva L1    16 larva L2    14 larva L3 12hr old    11 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    17 larva L3 puffstage 7-9    19 white prepupae new    20 white prepupae 12hr    22 white prepupae 24hr    29 pupae 2d postWPP    17 pupae 3d postWPP    8 pupae 4d postWPP    7 adult male 01day    9 adult male 05day    12 adult male 30day    13 adult female 01day    22 adult female 05day    32 adult female 30day    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    47 embryo 02-04hr    58 embryo 04-06hr    60 embryo 06-08hr    60 embryo 08-10hr    43 embryo 10-12hr    29 embryo 12-14hr    25 embryo 14-16hr    22 embryo 16-18hr    15 embryo 18-20hr    10 embryo 20-22hr    14 embryo 22-24hr    11 larva L1    16 larva L2    14 larva L3 12hr old    11 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    17 larva L3 puffstage 7-9    19 white prepupae new    20 white prepupae 12hr    22 white prepupae 24hr    29 pupae 2d postWPP    17 pupae 3d postWPP    8 pupae 4d postWPP    7 adult male 01day    9 adult male 05day    12 adult male 30day    13 adult female 01day    22 adult female 05day    32 adult female 30day    32 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    47 embryo 02-04hr    58 embryo 04-06hr    60 embryo 06-08hr    60 embryo 08-10hr    43 embryo 10-12hr    29 embryo 12-14hr    25 embryo 14-16hr    22 embryo 16-18hr    15 embryo 18-20hr    10 embryo 20-22hr    14 embryo 22-24hr    11 larva L1    16 larva L2    14 larva L3 12hr old    11 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    17 larva L3 puffstage 7-9    19 white prepupae new    20 white prepupae 12hr    22 white prepupae 24hr    29 pupae 2d postWPP    17 pupae 3d postWPP    8 pupae 4d postWPP    7 adult male 01day    9 adult male 05day    12 adult male 30day    13 adult female 01day    22 adult female 05day    32 adult female 30day    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (47) embryo 02-04hr  (58) embryo 04-06hr  (60) embryo 06-08hr  (60) embryo 08-10hr  (43) embryo 10-12hr  29 embryo 12-14hr    25 embryo 14-16hr    22 embryo 16-18hr    15 embryo 18-20hr    10 embryo 20-22hr    14 embryo 22-24hr    11 larva L1    16 larva L2    14 larva L3 12hr old    11 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    17 larva L3 puffstage 7-9    19 white prepupae new    20 white prepupae 12hr    22 white prepupae 24hr  29 pupae 2d postWPP    17 pupae 3d postWPP    8 pupae 4d postWPP    7 adult male 01day    9 adult male 05day    12 adult male 30day    13 adult female 01day    22 adult female 05day  32 adult female 30day  32 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    47 embryo 02-04hr    58 embryo 04-06hr    60 embryo 06-08hr    60 embryo 08-10hr    43 embryo 10-12hr    29 embryo 12-14hr    25 embryo 14-16hr    22 embryo 16-18hr    15 embryo 18-20hr    10 embryo 20-22hr    14 embryo 22-24hr    11 larva L1    16 larva L2    14 larva L3 12hr old    11 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    17 larva L3 puffstage 7-9    19 white prepupae new    20 white prepupae 12hr    22 white prepupae 24hr    29 pupae 2d postWPP    17 pupae 3d postWPP    8 pupae 4d postWPP    7 adult male 01day    9 adult male 05day    12 adult male 30day    13 adult female 01day    22 adult female 05day    32 adult female 30day    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    47 embryo 02-04hr    58 embryo 04-06hr    60 embryo 06-08hr    60 embryo 08-10hr    43 embryo 10-12hr    29 embryo 12-14hr    25 embryo 14-16hr    22 embryo 16-18hr    15 embryo 18-20hr    10 embryo 20-22hr    14 embryo 22-24hr    11 larva L1    16 larva L2    14 larva L3 12hr old    11 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    17 larva L3 puffstage 7-9    19 white prepupae new    20 white prepupae 12hr    22 white prepupae 24hr    29 pupae 2d postWPP    17 pupae 3d postWPP    8 pupae 4d postWPP    7 adult male 01day    9 adult male 05day    12 adult male 30day    13 adult female 01day    22 adult female 05day    32 adult female 30day    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    44 Schneider line 2 Sg4    38 embryonic 1182-4H    29 embryonic GM2    30 embryonic Kc167    33 embryonic S1    51 embryonic S3    34 leg disc CME L1    42 wing disc CME-W2    35 wing disc ML-DmD8    28 wing disc ML-DmD9    38 wing disc ML-DmD16-c3    34 wing disc ML-DmD21    37 wing disc ML-DmD32    32 haltere disc ML-DmD17-c3    38 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    27 mixed discs ML-DmD4-c1    37 CNS ML-DmBG1-c1    39 CNS ML-DmBG2-c2    26 tumorous blood cells mbn2    28 ovary fGS/OSS    46 ovary OSC    27 ovary OSS    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (44) Schneider line 2 Sg4  (38) embryonic 1182-4H  (29) embryonic GM2  (30) embryonic Kc167  (33) embryonic S1  (51) embryonic S3  (34) leg disc CME L1  (42) wing disc CME-W2  (35) wing disc ML-DmD8  (28) wing disc ML-DmD9  (38) wing disc ML-DmD16-c3  (34) wing disc ML-DmD21  (37) wing disc ML-DmD32  (32) haltere disc ML-DmD17-c3  (38) eye-antennal disc ML-DmD11  (29) antennal disc ML-DmD20-c5  (27) mixed discs ML-DmD4-c1  (37) CNS ML-DmBG1-c1  (39) CNS ML-DmBG2-c2  26 tumorous blood cells mbn2  (28) ovary fGS/OSS  (46) ovary OSC  (27) ovary OSS    22 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    44 Schneider line 2 Sg4    38 embryonic 1182-4H    29 embryonic GM2    30 embryonic Kc167    33 embryonic S1    51 embryonic S3    34 leg disc CME L1    42 wing disc CME-W2    35 wing disc ML-DmD8    28 wing disc ML-DmD9    38 wing disc ML-DmD16-c3    34 wing disc ML-DmD21    37 wing disc ML-DmD32    32 haltere disc ML-DmD17-c3    38 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    27 mixed discs ML-DmD4-c1    37 CNS ML-DmBG1-c1    39 CNS ML-DmBG2-c2    26 tumorous blood cells mbn2    28 ovary fGS/OSS    46 ovary OSC    27 ovary OSS    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    44 Schneider line 2 Sg4    38 embryonic 1182-4H    29 embryonic GM2    30 embryonic Kc167    33 embryonic S1    51 embryonic S3    34 leg disc CME L1    42 wing disc CME-W2    35 wing disc ML-DmD8    28 wing disc ML-DmD9    38 wing disc ML-DmD16-c3    34 wing disc ML-DmD21    37 wing disc ML-DmD32    32 haltere disc ML-DmD17-c3    38 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    27 mixed discs ML-DmD4-c1    37 CNS ML-DmBG1-c1    39 CNS ML-DmBG2-c2    26 tumorous blood cells mbn2    28 ovary fGS/OSS    46 ovary OSC    27 ovary OSS    22 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    44 Schneider line 2 Sg4    38 embryonic 1182-4H    29 embryonic GM2    30 embryonic Kc167    33 embryonic S1    51 embryonic S3    34 leg disc CME L1    42 wing disc CME-W2    35 wing disc ML-DmD8    28 wing disc ML-DmD9    38 wing disc ML-DmD16-c3    34 wing disc ML-DmD21    37 wing disc ML-DmD32    32 haltere disc ML-DmD17-c3    38 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    27 mixed discs ML-DmD4-c1    37 CNS ML-DmBG1-c1    39 CNS ML-DmBG2-c2    26 tumorous blood cells mbn2    28 ovary fGS/OSS    46 ovary OSC    27 ovary OSS    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (44) Schneider line 2 Sg4  (38) embryonic 1182-4H  29 embryonic GM2  30 embryonic Kc167  (33) embryonic S1  (51) embryonic S3  (34) leg disc CME L1  (42) wing disc CME-W2  (35) wing disc ML-DmD8  28 wing disc ML-DmD9  (38) wing disc ML-DmD16-c3  (34) wing disc ML-DmD21  (37) wing disc ML-DmD32  32 haltere disc ML-DmD17-c3  (38) eye-antennal disc ML-DmD11  29 antennal disc ML-DmD20-c5  27 mixed discs ML-DmD4-c1  (37) CNS ML-DmBG1-c1  (39) CNS ML-DmBG2-c2  26 tumorous blood cells mbn2  28 ovary fGS/OSS  (46) ovary OSC  27 ovary OSS    22 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    44 Schneider line 2 Sg4    38 embryonic 1182-4H    29 embryonic GM2    30 embryonic Kc167    33 embryonic S1    51 embryonic S3    34 leg disc CME L1    42 wing disc CME-W2    35 wing disc ML-DmD8    28 wing disc ML-DmD9    38 wing disc ML-DmD16-c3    34 wing disc ML-DmD21    37 wing disc ML-DmD32    32 haltere disc ML-DmD17-c3    38 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    27 mixed discs ML-DmD4-c1    37 CNS ML-DmBG1-c1    39 CNS ML-DmBG2-c2    26 tumorous blood cells mbn2    28 ovary fGS/OSS    46 ovary OSC    27 ovary OSS    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    44 Schneider line 2 Sg4    38 embryonic 1182-4H    29 embryonic GM2    30 embryonic Kc167    33 embryonic S1    51 embryonic S3    34 leg disc CME L1    42 wing disc CME-W2    35 wing disc ML-DmD8    28 wing disc ML-DmD9    38 wing disc ML-DmD16-c3    34 wing disc ML-DmD21    37 wing disc ML-DmD32    32 haltere disc ML-DmD17-c3    38 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    27 mixed discs ML-DmD4-c1    37 CNS ML-DmBG1-c1    39 CNS ML-DmBG2-c2    26 tumorous blood cells mbn2    28 ovary fGS/OSS    46 ovary OSC    27 ovary OSS    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    16 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    33 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    27 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    27 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    16 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult  (33) Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3  (36) Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (27) Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult  26 Paraquat 10 mM 48 hrs, 4-day adult  (27) Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    16 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    33 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    27 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    27 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    16 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    33 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    27 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    27 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    16 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    33 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    27 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    27 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    16 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult  (33) Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3  (36) Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  27 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult  26 Paraquat 10 mM 48 hrs, 4-day adult  27 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    16 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    33 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    27 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    27 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    16 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    33 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    27 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    27 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_17 mE1_20_mRNA_expression_cluster_04
External Data & Images
Linkouts	BDGP expression data • GH03554 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038464 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG16941-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4pnr-MD237 CG16941GD9241 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG16941 Class Mutagen Stocks Known lesion CG16941SH146 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG16941 Class Mutagen Stocks Known lesion CG16941GD9241 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG16941HMS00157 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG16941KK102272 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD9241} NA P{KK102272} NA P{TRiP.HMS00157} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{lacW}CG16941SH146 No
Gene Ontology: Function, Process & Cellular Component ( 10 unique terms )
Terms Based on Experimental Evidence ( 5 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
mitosis inferred from mutant phenotype (Ducat et al., 2008) mitotic spindle organization inferred from mutant phenotype (Goshima et al., 2007) regulation of alternative mRNA splicing, via spliceosome inferred from mutant phenotype (Park et al., 2004)
Cellular Component
CV term Evidence References
catalytic step 2 spliceosome inferred from direct assay (Herold et al., 2009) precatalytic spliceosome inferred from direct assay (Herold et al., 2009)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
RNA binding inferred from electronic annotation with InterPro:IPR000061 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
mRNA splicing, via spliceosome inferred by curator from GO:0071011|GO:0071013 (Herold et al., 2009) inferred from sequence or structural similarity with NCBI_gi:5032087 (FlyBase, 1992-) inferred from sequence or structural similarity with NCBI:NP_005868 AND inferred from sequence or structural similarity with Saccharomyces PRP21 (Mount and Salz, 2000)
Cellular Component
CV term Evidence References
nucleus inferred by curator from GO:0000381 (Park et al., 2004) spliceosomal complex inferred from sequence or structural similarity with NCBI_gi:5032087 (FlyBase, 1992-) U2 snRNP inferred from sequence or structural similarity with NCBI:NP_005868 AND inferred from sequence or structural similarity with Saccharomyces PRP21 (Mount and Salz, 2000)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG16941 - 14-3-3ζ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG16941 - Arpc2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG16941 - BEAF-32 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG16941 - CG10306 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG16941 - CG10754 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) CG16941 - CG11107 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG16941 - CG11266 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG16941 - CG11505 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG16941 - CG3817 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG16941 - Hsp23 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG16941 - Imp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG16941 - Ote anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG16941 - RpS19a anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG16941 - Syp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG16941 - ana2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG16941 - flw anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG16941 - kst anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG16941 - mRpL22 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG16941 - mRpS24 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG16941 - mRpS28 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG16941 - noi experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG16941 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 67089 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0038464 DroID - A comprehensive database of gene and protein interactions. • FBgn0038464 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42048
Orthologs
OrthoDB Orthologs (45) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6VQB7S Dipteran inclusive ortholog search EOG6Z36NW Insect inclusive ortholog search EOG6TX9MX Arthropod inclusive ortholog search EOG6JSXMK Metazoa inclusive ortholog search EOG6ND05P
Orthologs in Drosophila Species (EOG6VQB7S)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG16941     Drosophila simulans   Dsim\GD15098 Y   Drosophila sechellia   Dsec\GM15394 Y   Drosophila erecta   Dere\GG16800 Y   Drosophila yakuba   Dyak\GE26116 Y   Drosophila ananassae   Dana\GF17916 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA14228 Y   Drosophila persimilis   Dper\GL22994     Drosophila persimilis   Dper\GL22993     Drosophila willistoni   Dwil\GK12756 Y   Drosophila virilis   Dvir\GJ10593 Y   Drosophila mojavensis   Dmoj\GI23747 Y   Drosophila grimshawi   Dgri\GH18068 Y
Orthologs in non-Drosophila Dipterans (EOG6Z36NW)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL013818   Anopheles gambiae Malaria mosquito  Agam\AGAP011328   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ015416
Orthologs in non-Dipteran Insects (EOG6TX9MX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\SF3A1   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG004600   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG004590   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH14356   Atta cephalotes Leafcutter ant  Acep\ACEP26226   Atta cephalotes Leafcutter ant  Acep\ACEP21300   Camponotus floridanus Florida carpenter ant  Cflo\CFLO22942   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL21478   Linepithema humile Argentine ant  Lhum\LH10601   Pogonomyrmex barbatus Red harvester ant  Pbar\PB13984   Solenopsis invicta Red fire ant  Sinv\SINV22038   Acyrthosiphon pisum Pea aphid  Apim\ACYPI065062   Acyrthosiphon pisum Pea aphid  Apim\ACYPI001764   Bombyx mori Silkmoth  Bmor\BGIBMGA013595   Bombyx mori Silkmoth  Bmor\BGIBMGA013594   Pediculus humanus Human body louse  Phum\PHUM259560   Tribolium castaneum Red flour beetle  Tcas\TC004839
Orthologs in non-Insect Arthropods (EOG6JSXMK)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_196815
Orthologs in non-Arthropod Metazoa (EOG6ND05P)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\prp-21   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_012647gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_027895gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_026806gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_013513gn   Danio rerio Zebrafish  Drer\sf3a1   Xenopus tropicalis Western clawed frog  Xtro\sf3a1   Gallus gallus Domestic chicken  Ggal\SF3A1   Mus musculus House mouse  Mmus\Sf3a1   Rattus norvegicus Norway rat  Rnor\Sf3a1   Homo sapiens Human  Hsap\SF3A1
Human Orthologs (1)
Gene OMIM HGNC Hsap\SF3A1
AAA Orthologs (10) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD15098 Drosophila sechellia Dsec\GM15394 Drosophila erecta Dere\GG16800 Drosophila yakuba Dyak\GE26116 Drosophila ananassae Dana\GF17916 Drosophila pseudoobscura pseudoobscura Dpse\GA14228 Drosophila willistoni Dwil\GK12756 Drosophila virilis Dvir\GJ10593 Drosophila mojavensis Dmoj\GI23747 Drosophila grimshawi Dgri\GH18068
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	34840 y1 sc* v1; P{TRiP.HMS00157}attP2 29470 w*; P{neoFRT}82B P{lacW}CG16941SH146/TM3, Sb1
VDRC	v107162 P{KK102272}VIE-260B v20338 w1118; P{GD9241}v20338
Genomic Clones ( 1 )
	BACR03M20 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 78 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH03554
Other clones	DPiM_GH03554
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT08480 AT25441 AT26247 AT27393 GH24568 GH26755 GM03401 GM06771 GM22195 GM23414 LD18413 LD18480 LD22893 LD29245 RE13341 RE41677 RE42889 RE43635 RE48768 RE50668 RE56312 RE63722 RE64121 RH41303
Other clones	9779 44251 70384 164863 176908 191571 214415.39 214415.40 214569.33 281711 CK01.33C.D11 CK01.68D.C6 CK01.142B.G10 Dmel_dig_004988_0714_1335 EC38993 EK055033 EK119057 EK159739 EK188607 EK281664 EK295058 EK306924 EP02430 EP06038 EP09338 RP004055642 RP004070095 RP004081022 RP004090892 RP004122386 RP004128144 RP004156139 RP004200227 RP004201318 RP004207400 RP004209423 RP004212480 RP004221176 RP004229256 RP004238146 RP004256976 RP004261610 RP004263180 RP004266561 RP004321719 RP004339809 RP004347279 RP004417844 RP004450766 RP004524553 RP004537404 RP004545510
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0038464 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42048
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	RNAi screen using dsRNA made from templates generated with primers directed against this gene results in a long metaphase spindle with misaligned chromosomes when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA. (Goshima et al., 2007) Identified as a potential component of the hh signalling pathway in a genome-wide RNAi screen. dsRNA made from templates generated with primers directed affects the extent of expression of a hh signaling reporter construct in Clone 8 cells. (Nybakken et al., 2005) RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells. (Boutros et al., 2004)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_142326 RefSeq (Proteins) • NP_650583 DDBJ / EMBL / GenBank • AAF55372 AAK77262 AI063629 AI401918 AY047530 Entrez Gene - A searchable database of RefSeq genes. • 42048 UniProtKB/TrEMBL • Q9VEP9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • SWAP/Surp (IPR000061) Ubiquitin (IPR000626) Ubiquitin supergroup (IPR019955) Ubiquitin subgroup (IPR019956) Pre-mRNA splicing factor PRP21-like protein (IPR022030) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GH03554
Linkouts
	BioGRID - A database of protein and genetic interactions • 67089 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0038464 DroID - A comprehensive database of gene and protein interactions. • FBgn0038464 DRSC - Results from RNAi screens. • FBgn0038464 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038464 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG16941-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0038464 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42048 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42048 modMine - Data generated by the modENCODE project. • FBgn0038464
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	CG16941 (Nybakken et al., 2005, Goshima et al., 2007, Lin et al., 2010, Ducat et al., 2008, Keleman et al., 2009.8.5, Herold et al., 2009, McIntyre et al., 2006, Zhou et al., 2008, Pessa et al., 2010, Ni et al., 2011.7.19, Praveen et al., 2012, Lotti et al., 2012) SF3a1 (Pessa et al., 2010) Sf3a1 (Lotti et al., 2012) SF3a120 (Park et al., 2004)
Name Synonym	Splicing factor 3a, subunit 1 (Ducat et al., 2008)
Secondary FlyBase IDs
References ( 30 )
Generate a list of	All references relating to this gene ( 30 )
List References by type	Research paper  ( 11 ) Supplementary material  ( 8 ) Personal communication to FlyBase  ( 6 ) FlyBase analysis  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 2 )
	Lotti et al., 2012, Cell 151(2): 440--454 An SMN-Dependent U12 Splicing Event Essential for Motor Circuit Function. [FBrf0219670] Praveen et al., 2012, Cell Rep. 1(6): 624--631 A Drosophila Model of Spinal Muscular Atrophy Uncouples snRNP Biogenesis Functions of Survival Motor Neuron from Locomotion and Viability Defects. [FBrf0218971] Show all research papers ...