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Gene Dmel\CG18012

General Information
Symbol	Dmel\CG18012	Species	D. melanogaster
Name		Annotation symbol	CG18012
Feature type	protein_coding_gene	FlyBase ID	FBgn0038552
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	90C6-90C6	Sequence location	3R:13,635,123..13,636,848 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG18012 (FBgn0038552). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: beta-1,4-mannosyltransferase activity. Based on sequence similarity, it is predicted to be involved in the biological process: protein glycosylation. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Glycosyl transferase, family 1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult spermathecae, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult ovary, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1638157_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG18012. Gene sequence location is 3R:13635123..13636848.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features HFA15297 BKN46187 BKN28058
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 90C6-90C6   Limits computationally determined from genome sequence between P{PZ}l(3)0788207882 and P{EP}cpoEP3679
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG18012 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG18012-RA FBtr0083523  NM_142405   1607   446 CG18012-RB FBtr0303011  NM_001202317   1516   356
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG18012-PA   FBpp0082947   51.0   446   7.01     NP_650662   AAF55475 CG18012-PB   FBpp0292133   40.5   356   6.51     NP_001189246   ADV37337
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Glycosyl transferase, family 1 (IPR001296)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA141173   AA817319   AA978980   AE014297 AAF55475   AE014297 ADV37337   AI257231   AI455280   AI534999   AY118918 AAM50778   BF501372   BF505135   BG636795   BI212479   BI229605   BI358294   BI372508   BI483260   BI564378   BI567082   BI567863   BI568215   BI572629   BI572673   BI575391   BI575467   BI575731   BI576603   BI579156   BI583872   BI586036   BI586061   BI588384   BI591159   BI593249   BI610402   BI610786   BI626612   BI630060   BI634223   BI639239   BI639312   CK660029   CO190675   CO285174   CO285652   CO301015   CO335594   EC057181   EC069512   EC074121   EC200380   EC218297   EC223305   EC234454   EC262798   ES695526   ES695531   EV582033   EV583141
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VEE9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0038552    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0038552 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0038552 expression level Developmental Stage   Expression Level embryo 00-02hr    4454 embryo 02-04hr    3847 embryo 04-06hr    7143 embryo 06-08hr    5847 embryo 08-10hr    4181 embryo 10-12hr    3742 embryo 12-14hr    2022 embryo 14-16hr    1849 embryo 16-18hr    1621 embryo 18-20hr    2238 embryo 20-22hr    2087 embryo 22-24hr    1974 larva L1    2391 larva L2    2363 larva L3 12hr old    2306 larva L3 puffstage 1-2    1971 larva L3 puffstage 3-6    2061 larva L3 puffstage 7-9    1801 white prepupae new    1696 white prepupae 12hr    1356 white prepupae 24hr    1293 pupae 2d postWPP    991 pupae 3d postWPP    841 pupae 4d postWPP    1048 adult male 01day    1489 adult male 05day    1836 adult male 30day    1809 adult female 01day    2450 adult female 05day    2907 adult female 30day    3004 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4454) embryo 02-04hr  (3847) embryo 04-06hr  (7143) embryo 06-08hr  (5847) embryo 08-10hr  (4181) embryo 10-12hr  (3742) embryo 12-14hr  (2022) embryo 14-16hr  (1849) embryo 16-18hr  (1621) embryo 18-20hr  (2238) embryo 20-22hr  (2087) embryo 22-24hr  (1974) larva L1  (2391) larva L2  (2363) larva L3 12hr old  (2306) larva L3 puffstage 1-2  (1971) larva L3 puffstage 3-6  (2061) larva L3 puffstage 7-9  (1801) white prepupae new  (1696) white prepupae 12hr  (1356) white prepupae 24hr  (1293) pupae 2d postWPP  (991) pupae 3d postWPP  (841) pupae 4d postWPP  (1048) adult male 01day  (1489) adult male 05day  (1836) adult male 30day  (1809) adult female 01day  (2450) adult female 05day  (2907) adult female 30day  (3004) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4454) embryo 02-04hr  (3847) embryo 04-06hr  (7143) embryo 06-08hr  (5847) embryo 08-10hr  (4181) embryo 10-12hr  (3742) embryo 12-14hr  (2022) embryo 14-16hr  (1849) embryo 16-18hr  (1621) embryo 18-20hr  (2238) embryo 20-22hr  (2087) embryo 22-24hr  (1974) larva L1  (2391) larva L2  (2363) larva L3 12hr old  (2306) larva L3 puffstage 1-2  (1971) larva L3 puffstage 3-6  (2061) larva L3 puffstage 7-9  (1801) white prepupae new  (1696) white prepupae 12hr    1356 white prepupae 24hr    1293 pupae 2d postWPP    991 pupae 3d postWPP    841 pupae 4d postWPP    1048 adult male 01day  1489 adult male 05day  (1836) adult male 30day  (1809) adult female 01day  (2450) adult female 05day  (2907) adult female 30day  (3004) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4454 embryo 02-04hr    3847 embryo 04-06hr    7143 embryo 06-08hr    5847 embryo 08-10hr    4181 embryo 10-12hr    3742 embryo 12-14hr    2022 embryo 14-16hr    1849 embryo 16-18hr    1621 embryo 18-20hr    2238 embryo 20-22hr    2087 embryo 22-24hr    1974 larva L1    2391 larva L2    2363 larva L3 12hr old    2306 larva L3 puffstage 1-2    1971 larva L3 puffstage 3-6    2061 larva L3 puffstage 7-9    1801 white prepupae new    1696 white prepupae 12hr    1356 white prepupae 24hr    1293 pupae 2d postWPP    991 pupae 3d postWPP    841 pupae 4d postWPP    1048 adult male 01day    1489 adult male 05day    1836 adult male 30day    1809 adult female 01day    2450 adult female 05day    2907 adult female 30day    3004 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4454 embryo 02-04hr    3847 embryo 04-06hr    7143 embryo 06-08hr    5847 embryo 08-10hr    4181 embryo 10-12hr    3742 embryo 12-14hr    2022 embryo 14-16hr    1849 embryo 16-18hr    1621 embryo 18-20hr    2238 embryo 20-22hr    2087 embryo 22-24hr    1974 larva L1    2391 larva L2    2363 larva L3 12hr old    2306 larva L3 puffstage 1-2    1971 larva L3 puffstage 3-6    2061 larva L3 puffstage 7-9    1801 white prepupae new    1696 white prepupae 12hr    1356 white prepupae 24hr    1293 pupae 2d postWPP    991 pupae 3d postWPP    841 pupae 4d postWPP    1048 adult male 01day    1489 adult male 05day    1836 adult male 30day    1809 adult female 01day    2450 adult female 05day    2907 adult female 30day    3004 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0038552 expression level Developmental Stage   Expression Level embryo 00-02hr    4454 embryo 02-04hr    3847 embryo 04-06hr    7143 embryo 06-08hr    5847 embryo 08-10hr    4181 embryo 10-12hr    3742 embryo 12-14hr    2022 embryo 14-16hr    1849 embryo 16-18hr    1621 embryo 18-20hr    2238 embryo 20-22hr    2087 embryo 22-24hr    1974 larva L1    2391 larva L2    2363 larva L3 12hr old    2306 larva L3 puffstage 1-2    1971 larva L3 puffstage 3-6    2061 larva L3 puffstage 7-9    1801 white prepupae new    1696 white prepupae 12hr    1356 white prepupae 24hr    1293 pupae 2d postWPP    991 pupae 3d postWPP    841 pupae 4d postWPP    1048 adult male 01day    1489 adult male 05day    1836 adult male 30day    1809 adult female 01day    2450 adult female 05day    2907 adult female 30day    3004 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4454) embryo 02-04hr  (3847) embryo 04-06hr  (7143) embryo 06-08hr  (5847) embryo 08-10hr  (4181) embryo 10-12hr  (3742) embryo 12-14hr  (2022) embryo 14-16hr  (1849) embryo 16-18hr  (1621) embryo 18-20hr  (2238) embryo 20-22hr  (2087) embryo 22-24hr  (1974) larva L1  (2391) larva L2  (2363) larva L3 12hr old  (2306) larva L3 puffstage 1-2  (1971) larva L3 puffstage 3-6  (2061) larva L3 puffstage 7-9  (1801) white prepupae new  (1696) white prepupae 12hr  (1356) white prepupae 24hr  (1293) pupae 2d postWPP  (991) pupae 3d postWPP  (841) pupae 4d postWPP  (1048) adult male 01day  (1489) adult male 05day  (1836) adult male 30day  (1809) adult female 01day  (2450) adult female 05day  (2907) adult female 30day  (3004) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4454) embryo 02-04hr  (3847) embryo 04-06hr  (7143) embryo 06-08hr  (5847) embryo 08-10hr  (4181) embryo 10-12hr  (3742) embryo 12-14hr  2022 embryo 14-16hr  1849 embryo 16-18hr  1621 embryo 18-20hr  2238 embryo 20-22hr  2087 embryo 22-24hr  1974 larva L1  2391 larva L2  2363 larva L3 12hr old  2306 larva L3 puffstage 1-2  1971 larva L3 puffstage 3-6  2061 larva L3 puffstage 7-9  1801 white prepupae new  1696 white prepupae 12hr    1356 white prepupae 24hr    1293 pupae 2d postWPP    991 pupae 3d postWPP    841 pupae 4d postWPP    1048 adult male 01day  1489 adult male 05day  1836 adult male 30day  1809 adult female 01day  2450 adult female 05day  (2907) adult female 30day  (3004) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4454 embryo 02-04hr    3847 embryo 04-06hr    7143 embryo 06-08hr    5847 embryo 08-10hr    4181 embryo 10-12hr    3742 embryo 12-14hr    2022 embryo 14-16hr    1849 embryo 16-18hr    1621 embryo 18-20hr    2238 embryo 20-22hr    2087 embryo 22-24hr    1974 larva L1    2391 larva L2    2363 larva L3 12hr old    2306 larva L3 puffstage 1-2    1971 larva L3 puffstage 3-6    2061 larva L3 puffstage 7-9    1801 white prepupae new    1696 white prepupae 12hr    1356 white prepupae 24hr    1293 pupae 2d postWPP    991 pupae 3d postWPP    841 pupae 4d postWPP    1048 adult male 01day    1489 adult male 05day    1836 adult male 30day    1809 adult female 01day    2450 adult female 05day    2907 adult female 30day    3004 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4454 embryo 02-04hr    3847 embryo 04-06hr    7143 embryo 06-08hr    5847 embryo 08-10hr    4181 embryo 10-12hr    3742 embryo 12-14hr    2022 embryo 14-16hr    1849 embryo 16-18hr    1621 embryo 18-20hr    2238 embryo 20-22hr    2087 embryo 22-24hr    1974 larva L1    2391 larva L2    2363 larva L3 12hr old    2306 larva L3 puffstage 1-2    1971 larva L3 puffstage 3-6    2061 larva L3 puffstage 7-9    1801 white prepupae new    1696 white prepupae 12hr    1356 white prepupae 24hr    1293 pupae 2d postWPP    991 pupae 3d postWPP    841 pupae 4d postWPP    1048 adult male 01day    1489 adult male 05day    1836 adult male 30day    1809 adult female 01day    2450 adult female 05day    2907 adult female 30day    3004 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0038552    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0038552 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult spermathecae, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult ovary, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0038552 expression level Tissue   Expression Level Larval Central Nervous System    133.9 Larval Midgut    267.2 Larval Hindgut    209.5 Larval Malpighian Tubules    140.6 Larval Fat Body    228.6 Larval Salivary Gland    362.7 Larval Trachea    293.1 Larval Carcass    144.45 Adult Head    201.4 Adult Eye    181.1 Adult Brain    86.6 Adult Thoracic-Abdominal Ganglion    98.6 Adult Crop    242.1 Adult Midgut    295.6 Adult Hindgut    203.1 Adult Malpighian Tubules    175.1 Adult Fat Body    407.1 Adult Salivary Gland    359.6 Adult Heart    308.5 Adult VirginFemale Spermatheca    775.6 Adult InseminatedFemale Spermatheca    761.8 Adult Ovary    291.8 Adult Testis    52.3 Adult Male Accessory Gland    731.3 Adult Carcass    228.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    133.9 Larval Midgut    267.2 Larval Hindgut    209.5 Larval Malpighian Tubules    140.6 Larval Fat Body    228.6 Larval Salivary Gland    362.7 Larval Trachea    293.1 Larval Carcass    144.45 Adult Head    201.4 Adult Eye    181.1 Adult Brain    86.6 Adult Thoracic-Abdominal Ganglion    98.6 Adult Crop    242.1 Adult Midgut    295.6 Adult Hindgut    203.1 Adult Malpighian Tubules    175.1 Adult Fat Body    407.1 Adult Salivary Gland    359.6 Adult Heart    308.5 Adult VirginFemale Spermatheca  (775.6) Adult InseminatedFemale Spermatheca  (761.8) Adult Ovary    291.8 Adult Testis    52.3 Adult Male Accessory Gland  (731.3) Adult Carcass    228.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    133.9 Larval Midgut    267.2 Larval Hindgut    209.5 Larval Malpighian Tubules    140.6 Larval Fat Body    228.6 Larval Salivary Gland    362.7 Larval Trachea    293.1 Larval Carcass    144.45 Adult Head    201.4 Adult Eye    181.1 Adult Brain    86.6 Adult Thoracic-Abdominal Ganglion    98.6 Adult Crop    242.1 Adult Midgut    295.6 Adult Hindgut    203.1 Adult Malpighian Tubules    175.1 Adult Fat Body    407.1 Adult Salivary Gland    359.6 Adult Heart    308.5 Adult VirginFemale Spermatheca    775.6 Adult InseminatedFemale Spermatheca    761.8 Adult Ovary    291.8 Adult Testis    52.3 Adult Male Accessory Gland    731.3 Adult Carcass    228.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    133.9 Larval Midgut    267.2 Larval Hindgut    209.5 Larval Malpighian Tubules    140.6 Larval Fat Body    228.6 Larval Salivary Gland    362.7 Larval Trachea    293.1 Larval Carcass    144.45 Adult Head    201.4 Adult Eye    181.1 Adult Brain    86.6 Adult Thoracic-Abdominal Ganglion    98.6 Adult Crop    242.1 Adult Midgut    295.6 Adult Hindgut    203.1 Adult Malpighian Tubules    175.1 Adult Fat Body    407.1 Adult Salivary Gland    359.6 Adult Heart    308.5 Adult VirginFemale Spermatheca    775.6 Adult InseminatedFemale Spermatheca    761.8 Adult Ovary    291.8 Adult Testis    52.3 Adult Male Accessory Gland    731.3 Adult Carcass    228.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0038552 expression level Tissue   Expression Level Larval Central Nervous System    133.9 Larval Midgut    267.2 Larval Hindgut    209.5 Larval Malpighian Tubules    140.6 Larval Fat Body    228.6 Larval Salivary Gland    362.7 Larval Trachea    293.1 Larval Carcass    144.45 Adult Head    201.4 Adult Eye    181.1 Adult Brain    86.6 Adult Thoracic-Abdominal Ganglion    98.6 Adult Crop    242.1 Adult Midgut    295.6 Adult Hindgut    203.1 Adult Malpighian Tubules    175.1 Adult Fat Body    407.1 Adult Salivary Gland    359.6 Adult Heart    308.5 Adult VirginFemale Spermatheca    775.6 Adult InseminatedFemale Spermatheca    761.8 Adult Ovary    291.8 Adult Testis    52.3 Adult Male Accessory Gland    731.3 Adult Carcass    228.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    133.9 Larval Midgut    267.2 Larval Hindgut    209.5 Larval Malpighian Tubules    140.6 Larval Fat Body    228.6 Larval Salivary Gland    362.7 Larval Trachea    293.1 Larval Carcass    144.45 Adult Head    201.4 Adult Eye    181.1 Adult Brain    86.6 Adult Thoracic-Abdominal Ganglion    98.6 Adult Crop    242.1 Adult Midgut    295.6 Adult Hindgut    203.1 Adult Malpighian Tubules    175.1 Adult Fat Body    407.1 Adult Salivary Gland    359.6 Adult Heart    308.5 Adult VirginFemale Spermatheca  775.6 Adult InseminatedFemale Spermatheca  761.8 Adult Ovary    291.8 Adult Testis    52.3 Adult Male Accessory Gland  731.3 Adult Carcass    228.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    133.9 Larval Midgut    267.2 Larval Hindgut    209.5 Larval Malpighian Tubules    140.6 Larval Fat Body    228.6 Larval Salivary Gland    362.7 Larval Trachea    293.1 Larval Carcass    144.45 Adult Head    201.4 Adult Eye    181.1 Adult Brain    86.6 Adult Thoracic-Abdominal Ganglion    98.6 Adult Crop    242.1 Adult Midgut    295.6 Adult Hindgut    203.1 Adult Malpighian Tubules    175.1 Adult Fat Body    407.1 Adult Salivary Gland    359.6 Adult Heart    308.5 Adult VirginFemale Spermatheca    775.6 Adult InseminatedFemale Spermatheca    761.8 Adult Ovary    291.8 Adult Testis    52.3 Adult Male Accessory Gland    731.3 Adult Carcass    228.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    133.9 Larval Midgut    267.2 Larval Hindgut    209.5 Larval Malpighian Tubules    140.6 Larval Fat Body    228.6 Larval Salivary Gland    362.7 Larval Trachea    293.1 Larval Carcass    144.45 Adult Head    201.4 Adult Eye    181.1 Adult Brain    86.6 Adult Thoracic-Abdominal Ganglion    98.6 Adult Crop    242.1 Adult Midgut    295.6 Adult Hindgut    203.1 Adult Malpighian Tubules    175.1 Adult Fat Body    407.1 Adult Salivary Gland    359.6 Adult Heart    308.5 Adult VirginFemale Spermatheca    775.6 Adult InseminatedFemale Spermatheca    761.8 Adult Ovary    291.8 Adult Testis    52.3 Adult Male Accessory Gland    731.3 Adult Carcass    228.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    201.4   NA  Eye    181.1   NA  Brain    86.6   133.9  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    98.6   NA  Crop    242.1   267.2  Midgut    295.6   209.5  Hindgut    203.1   140.6  Malpighian Tubules    175.1   228.6  Fat Body    407.1   362.7  Salivary Gland    359.6   NA  Heart    308.5   293.1  Trachea    NA   NA  VirginFemale Spermatheca    775.6   NA  InseminatedFemale Spermatheca    761.8   NA  Ovary    291.8   NA  Testis    52.3   NA  Male Accessory Gland    731.3   144.45  Carcass    228.5 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_03
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038552 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG18012-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pupal stage, with Scer\GAL4pnr-MD237 CG18012GD9500 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG18012 Class Mutagen Stocks Known lesion CG18012CB-0272-3 1 -- CG18012DG30611 1 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG18012 Class Mutagen Stocks Known lesion CG18012GD9500 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD9500} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{RS3}CG18012CB-0272-3 NA P{wHy}CG18012DG30611 NA insertion of mobile activating element P{Mae-UAS.6.11}UY2517UY2517 NA
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
beta-1,4-mannosyltransferase activity inferred from sequence or structural similarity with Saccharomyces ALG1 (FlyBase, 1992-)
Biological Process
CV term Evidence References
protein glycosylation inferred from sequence or structural similarity with Saccharomyces ALG1 (FlyBase, 1992-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG18012 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 67178 DroID - A comprehensive database of gene and protein interactions. • FBgn0038552 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42146
Orthologs
Genome-wide drosophilid orthologs	Dana\GF18249 Dere\GG16746 Dgri\GH17347 Dmoj\GI23885 Dper\GL12024 Dpse\GA26165 Dsec\GM15332 Dsim\GD20206 Dvir\GJ23978 Dwil\GK11839 Dyak\GE25241
Curated drosophilid orthologs
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL000451-PA Aedes aegypti (mosquito) AGAP003551-PA Anopheles gambiae (mosquito) XP_623777.2 Apis mellifera (honey bee) XP_001952785.1 Acyrthosiphon pisum (pea aphid) At1g16570.1 Arabidopsis thaliana (wall cress) 10975 Batrachochytrium dendrobatidis (chytrid fungus) 125098 Branchiostoma floridae (lancelet) XP_001902976.1 Brugia malayi (roundworm nematode) BGIBMGA011976-PA Bombyx mori (silk worm) ENSBTAP00000002836 Bos taurus (bovine) CAL0001745 Candida albicans (a form of yeast) CN19741 Caenorhabditis brenneri (small nematode) CBP31850 Caenorhabditis briggsae (nematode) CE42024 Caenorhabditis elegans (worm) ENSCAFP00000028202 Canis familiaris (dog) CAGL0K12342g Candida glabrata (haploid yeast) ENSCINP00000014812 Ciona intestinalis (sea squirt) JA04623 Caenorhabditis japonica (nematode) CMR050C Cyanidioschyzon merolae (red alga) cn01659 Cryptococcus neoformans (yeast-like fungus) cgd7_1810 Cryptosporidium parvum (protozoan parasite) CPIJ007482 Culex pipens (mosquito) ENSCPOP00000012445 Cavia porcellus (guinea pig) 108570 Chlamidomonas reinhardtii (green alga) RP40044 Caenorhabditis remanei (nematode) 145760 Capitella spl (polychaete worm) DDB0191150 Dictyostelium discoideum (amoeba) DEHA2D10516g Debaryomyces Hansenii (yeast) 304651 Daphnia pulex (daphnia) ENSDARP00000071703 Danio rerio (zebra fish) ENSECAP00000006228 Equus caballus (horse) XP_650919 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000019722 Gymnopilus aculeatus (mushroom) ENSGALP00000003213 Gallus gallus (chicken) 101462 Hypsipyla robusta (cedar shoot borer) ENSP00000262374 Homo sapiens (human) KLLA0B09405g Kluyveromyces lactis (yeast) 210506 Lottia gigantea (owl limpet) LmjF18.0900 Leishmania major (virus) 29828 Monocosta brevicollis (choanoflagellate) ENSMODP00000007326 Monodelphis domestica (gray opossum) ENSMMUP00000009839 Macaca mulatta (rhesus monkey) ENSMUSP00000097770 Mus musculus (house mouse) 212177 Nematostella vectensis (starlet anemone) XP_001601332.1 Nasonia vitripennis (wasp) ENSORLP00000000403 Oryzias latipes (japanese killifish) LOC_Os03g08300.1 Oryza sativa (asian rice) 21721 Ostreococcus tauri (green alga) PHUM004531-PA Pediculus humanus (human body louse) 50684 Physcomitrella patens (moss) ENSPPYP00000008002 Pongo pygmaeus (orangutan) 46727 Phytophthora ramorum (sudden oak death pathogen) 113542 Phytophthora sojae (root rot pathogen) 583054 Populus trichocarpa (black cottonwood) ENSPTRP00000013215 Pan troglodytes (chimpanzee) ENSRNOP00000003856 Rattus norvegicus (norway rat) 4745601 Sorghum bicolor (sorghum) YBR110W Saccharomyces cerevisiae (budding yeast) Smp_005010 Schistosoma mansoni (trematode parasite) SPAC23C4.14 Schizosaccharomyces pombe (fission yeast) XP_001179998.1 Strongylocentrotus purpuratus (purple sea urchin) 33634 Trichoplax adhaerens (metazoa) XP_975242.1 Tribolium castaneum (red flour beetle) Tc00.1047053504215.20 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000001995 Tetraodon nigroviridis (green spotted pufferfish) ENSTNIP00000010949 Tetraodon nigroviridis (green spotted pufferfish) 14643 Thalassiosira pseudonana (marine diatom) ENSTRUP00000000968 Takifugu rubripes (pufferfish Takifugu) 176.m00069 Tetrahymena thermophila (ciliate protozoa) 82312.m00036 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000054572 Xenopus tropicalis (frog) YALI0E34133g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17822 NV17559 LH17054 ISCW018248 FBgn0242324 FBgn0213850 FBgn0211065 FBgn0191684 FBgn0170252 JGI_V11_304651 FBgn0247541 FBgn0149632 FBgn0146610 FBgn0124817 FBgn0108976 FBgn0095267 CPIJ007482 BGIBMGA011976 ACYPI007591 GB14557 AGAP003551 AAEL000451 PHUM232220 GLEAN_03528
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	21333 y1 w67c23; P{wHy}CG18012DG30611/TM3, Sb1 Ser1
Kyoto	123101 w1118; P{RS3}CG18012CB-0272-3
VDRC	v20580 w1118; P{GD9500}v20580
Genomic Clones ( 2 )
	BACR14A01 BACR45M04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 54 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD22559
Other clones	DPiM_LD22559
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT07307 AT16667 LD33208 LP05538 LP18248 RE17576 RE27422 RE45027 RE59487 RE66131 RE73142 RH04883 RH08217 RH08270 RH11234 RH15861 RH16589 RH22584 RH25756 RH25788 RH29580 RH31012 RH31136 RH32033 RH33193 RH36923 RH37273 RH37650 RH38563 RH39612 RH59023 RH67610 SD01326 SD14581 SD21769 SD21867
Other clones	54812 56957 59844 60003 523284 CK01.10B.B6 CK01.60B.G1 CK01.60D.F12 CK01316 Dmel_dig_006726_0682_3463 Dmel_dig_014569_0671_0750 EK049042 EK168431 EK169760 EK179911 EN10803
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0038552 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42146
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_142405 NM_001202317 RefSeq (Proteins) • NP_650662 NP_001189246 DDBJ / EMBL / GenBank • AA817319 AAF55475 AAM50778 ADV37337 AI455280 AY118918 Entrez Gene - A searchable database of RefSeq genes. • 42146 UniProtKB/TrEMBL • Q9VEE9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Glycosyl transferase, family 1 (IPR001296)
Linkouts
	BioGRID - A database of protein and genetic interactions • 67178 DroID - A comprehensive database of gene and protein interactions. • FBgn0038552 DRSC - Results from RNAi screens. • FBgn0038552 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038552 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG18012-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0038552 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42146 InParanoid A subset of ortholog calls from InParanoid. • AAEL000451-PA Aedes aegypti (mosquito) AGAP003551-PA Anopheles gambiae (mosquito) XP_623777.2 Apis mellifera (honey bee) XP_001952785.1 Acyrthosiphon pisum (pea aphid) At1g16570.1 Arabidopsis thaliana (wall cress) 10975 Batrachochytrium dendrobatidis (chytrid fungus) 125098 Branchiostoma floridae (lancelet) XP_001902976.1 Brugia malayi (roundworm nematode) BGIBMGA011976-PA Bombyx mori (silk worm) ENSBTAP00000002836 Bos taurus (bovine) CAL0001745 Candida albicans (a form of yeast) CN19741 Caenorhabditis brenneri (small nematode) CBP31850 Caenorhabditis briggsae (nematode) CE42024 Caenorhabditis elegans (worm) ENSCAFP00000028202 Canis familiaris (dog) CAGL0K12342g Candida glabrata (haploid yeast) ENSCINP00000014812 Ciona intestinalis (sea squirt) JA04623 Caenorhabditis japonica (nematode) CMR050C Cyanidioschyzon merolae (red alga) cn01659 Cryptococcus neoformans (yeast-like fungus) cgd7_1810 Cryptosporidium parvum (protozoan parasite) CPIJ007482 Culex pipens (mosquito) ENSCPOP00000012445 Cavia porcellus (guinea pig) 108570 Chlamidomonas reinhardtii (green alga) RP40044 Caenorhabditis remanei (nematode) 145760 Capitella spl (polychaete worm) DDB0191150 Dictyostelium discoideum (amoeba) DEHA2D10516g Debaryomyces Hansenii (yeast) 304651 Daphnia pulex (daphnia) ENSDARP00000071703 Danio rerio (zebra fish) ENSECAP00000006228 Equus caballus (horse) XP_650919 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000019722 Gymnopilus aculeatus (mushroom) ENSGALP00000003213 Gallus gallus (chicken) 101462 Hypsipyla robusta (cedar shoot borer) ENSP00000262374 Homo sapiens (human) KLLA0B09405g Kluyveromyces lactis (yeast) 210506 Lottia gigantea (owl limpet) LmjF18.0900 Leishmania major (virus) 29828 Monocosta brevicollis (choanoflagellate) ENSMODP00000007326 Monodelphis domestica (gray opossum) ENSMMUP00000009839 Macaca mulatta (rhesus monkey) ENSMUSP00000097770 Mus musculus (house mouse) 212177 Nematostella vectensis (starlet anemone) XP_001601332.1 Nasonia vitripennis (wasp) ENSORLP00000000403 Oryzias latipes (japanese killifish) LOC_Os03g08300.1 Oryza sativa (asian rice) 21721 Ostreococcus tauri (green alga) PHUM004531-PA Pediculus humanus (human body louse) 50684 Physcomitrella patens (moss) ENSPPYP00000008002 Pongo pygmaeus (orangutan) 46727 Phytophthora ramorum (sudden oak death pathogen) 113542 Phytophthora sojae (root rot pathogen) 583054 Populus trichocarpa (black cottonwood) ENSPTRP00000013215 Pan troglodytes (chimpanzee) ENSRNOP00000003856 Rattus norvegicus (norway rat) 4745601 Sorghum bicolor (sorghum) YBR110W Saccharomyces cerevisiae (budding yeast) Smp_005010 Schistosoma mansoni (trematode parasite) SPAC23C4.14 Schizosaccharomyces pombe (fission yeast) XP_001179998.1 Strongylocentrotus purpuratus (purple sea urchin) 33634 Trichoplax adhaerens (metazoa) XP_975242.1 Tribolium castaneum (red flour beetle) Tc00.1047053504215.20 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000001995 Tetraodon nigroviridis (green spotted pufferfish) ENSTNIP00000010949 Tetraodon nigroviridis (green spotted pufferfish) 14643 Thalassiosira pseudonana (marine diatom) ENSTRUP00000000968 Takifugu rubripes (pufferfish Takifugu) 176.m00069 Tetrahymena thermophila (ciliate protozoa) 82312.m00036 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000054572 Xenopus tropicalis (frog) YALI0E34133g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42146 modMine - Data generated by the modENCODE project. • FBgn0038552 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17822 NV17559 LH17054 ISCW018248 FBgn0242324 FBgn0213850 FBgn0211065 FBgn0191684 FBgn0170252 JGI_V11_304651 FBgn0247541 FBgn0149632 FBgn0146610 FBgn0124817 FBgn0108976 FBgn0095267 CPIJ007482 BGIBMGA011976 ACYPI007591 GB14557 AGAP003551 AAEL000451 PHUM232220 GLEAN_03528
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG18012 (Li et al., 2009)
Name Synonym
Secondary FlyBase IDs
References ( 16 )
Research paper	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Li et al., 2009, Insect Molec. Biol. 18(1): 21--31 Transcriptional signatures in response to wheat germ agglutinin and starvation in Drosophila melanogaster larval midgut. [FBrf0206697] Bjorklund et al., 2006, Nature 439(7079): 1009--1013 Identification of pathways regulating cell size and cell-cycle progression by RNAi. [FBrf0191233] Orian et al., 2003, Genes Dev. 17(9): 1101--1114 Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. [FBrf0158942] Monnier et al., 2002, genesis 34(1-2): 76--79 Modulation of oxidative stress resistance in Drosophila melanogaster by gene overexpression. [FBrf0152382]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Gelbart, 2008.3.31, DG.xml DG.xml [FBrf0204101] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Myrick et al., 2005.5.16, Deletion Generator Project genomic insertion collection. Deletion Generator Project genomic insertion collection. [FBrf0188490] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]