FB2025_01 , released February 20, 2025
Gene: Dmel\CG14297
Open Close
General Information
Symbol
Dmel\CG14297
Species
D. melanogaster
Name
Annotation Symbol
CG14297
Feature Type
protein_coding_gene
FlyBase ID
FBgn0038655
Gene Model Status
Current
Stock Availability
7 publicly available
Enzyme Name (EC)
protein-tyrosine-phosphatase (3.1.3.48)
Gene Summary
Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; conduct disorder; diabetes mellitus (multiple); diabetic retinopathy; and obesity. Orthologous to human ACP1 (acid phosphatase 1). (Alliance, FBgn0038655 )
Contribute a Gene Snapshot for this gene.
All Summaries
Key Links
Genomic Location
Cytogenetic map
91D4-91D4
Sequence location
Recombination map
3-65
RefSeq locus
NT_033777 REGION:18898121..18899342
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function

GO Summary Ribbons

enzyme
regulator
receptor
receptor binding
transporter
structural molecule
cytoskeletal binding
DNA binding
RNA binding
transcription factor
small molecule binding
metal ion binding
lipid binding
carbohydrate binding
other molecular_function
molecular function
cell cycle/proliferation
cell organization/biogenesis
transport/localization
development
reproduction
immune system
nervous system process
behavior
response to stimulus
signaling
gene expression
protein metabolism
DNA metabolism
small molecule metabolism
other biological_process
biological process
extracellular region
cytosol
cytoskeleton
mitochondrion
nucleus
chromosome
membrane
cell periphery
cell junction
cell projection
endomembrane system
synapse
macromolecular complex
other cellular_component
cellular component
Gene Ontology (GO) Annotations (3 terms)
Molecular Function (1 term)
Biological Process (0 terms)
Cellular Component (2 terms)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Catalytic Activity (EC/Rhea)
protein tyrosine phosphatase activity
O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate (3.1.3.48)
RHEA 10684:
Summaries
Gene Model and Products
Expression Data

Gene ToolKit

Alleles, Insertions, Transgenic Constructs, and Aberrations
Variants
Phenotypes
Orthologs
Paralogs
Human Disease Associations
Functional Complementation Data
Interactions
Pathways
Class of Gene
Genomic Location and Detailed Mapping Data
Stocks and Reagents
Other Comments
Relationship to Other Genes
Nomenclature History
Synonyms and Secondary IDs (2)
Datasets (0)
External Crossreferences and Linkouts ( 31 )
References (27)