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Gene Dmel\CG14291

General Information
Symbol	Dmel\CG14291	Species	D. melanogaster
Name		Annotation symbol	CG14291
Feature type	protein_coding_gene	FlyBase ID	FBgn0038660
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	91D4-91D4	Sequence location	3R:14,736,773..14,738,641 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG14291 (FBgn0038660). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: N-sulfoglucosamine sulfohydrolase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: metabolic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Alkaline phosphatase-like, alpha/beta/alpha; Alkaline-phosphatase-like, core domain; Sulfatase; Sulfatase, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 06-18 hour embryonic stages, during late pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval fat body. Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval hindgut, larval trachea, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1639834_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG14291. Gene sequence location is 3R:14736773..14738641.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features BKN21258 HFA14771
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 91D4-91D4   Limits computationally determined from genome sequence between P{PZ}sprd05284 and P{PZ}cdi07013&P{lacW}nosj3B6
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG14291 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG14291-RA FBtr0083724  NM_142503   1869   524
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG14291-PA   FBpp0083138   59.9   524   7.09     NP_650760   AAF55607
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Sulfatase (IPR000917) Alkaline phosphatase-like, alpha/beta/alpha (IPR017849) Alkaline-phosphatase-like, core domain (IPR017850) Sulfatase, conserved site (IPR024607)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF55607   AY071569 AAL49191   BI167030   BI167040   BI170719   BI212677   BI212766   BI214866   BI355982   BI358141   BI375460   CO297312   EC064440   EC220924
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VE24
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0038660    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0038660 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 06-18 hour embryonic stages, during late pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0038660 expression level Developmental Stage   Expression Level embryo 00-02hr    32 embryo 02-04hr    326 embryo 04-06hr    1489 embryo 06-08hr    2133 embryo 08-10hr    2728 embryo 10-12hr    4513 embryo 12-14hr    4468 embryo 14-16hr    2626 embryo 16-18hr    676 embryo 18-20hr    268 embryo 20-22hr    80 embryo 22-24hr    106 larva L1    198 larva L2    1645 larva L3 12hr old    1086 larva L3 puffstage 1-2    1653 larva L3 puffstage 3-6    2441 larva L3 puffstage 7-9    2441 white prepupae new    2730 white prepupae 12hr    1216 white prepupae 24hr    3286 pupae 2d postWPP    8106 pupae 3d postWPP    622 pupae 4d postWPP    216 adult male 01day    189 adult male 05day    182 adult male 30day    210 adult female 01day    126 adult female 05day    63 adult female 30day    59 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    32 embryo 02-04hr  (326) embryo 04-06hr  (1489) embryo 06-08hr  (2133) embryo 08-10hr  (2728) embryo 10-12hr  (4513) embryo 12-14hr  (4468) embryo 14-16hr  (2626) embryo 16-18hr  (676) embryo 18-20hr  (268) embryo 20-22hr    80 embryo 22-24hr  106 larva L1  (198) larva L2  (1645) larva L3 12hr old  (1086) larva L3 puffstage 1-2  (1653) larva L3 puffstage 3-6  (2441) larva L3 puffstage 7-9  (2441) white prepupae new  (2730) white prepupae 12hr  (1216) white prepupae 24hr  (3286) pupae 2d postWPP  (8106) pupae 3d postWPP  (622) pupae 4d postWPP  (216) adult male 01day  (189) adult male 05day  (182) adult male 30day  (210) adult female 01day  (126) adult female 05day    63 adult female 30day    59 Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    32 embryo 02-04hr    326 embryo 04-06hr  1489 embryo 06-08hr  (2133) embryo 08-10hr  (2728) embryo 10-12hr  (4513) embryo 12-14hr  (4468) embryo 14-16hr  (2626) embryo 16-18hr    676 embryo 18-20hr    268 embryo 20-22hr    80 embryo 22-24hr    106 larva L1    198 larva L2  (1645) larva L3 12hr old    1086 larva L3 puffstage 1-2  (1653) larva L3 puffstage 3-6  (2441) larva L3 puffstage 7-9  (2441) white prepupae new  (2730) white prepupae 12hr    1216 white prepupae 24hr  (3286) pupae 2d postWPP  (8106) pupae 3d postWPP    622 pupae 4d postWPP    216 adult male 01day    189 adult male 05day    182 adult male 30day    210 adult female 01day    126 adult female 05day    63 adult female 30day    59 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    32 embryo 02-04hr    326 embryo 04-06hr    1489 embryo 06-08hr    2133 embryo 08-10hr    2728 embryo 10-12hr    4513 embryo 12-14hr    4468 embryo 14-16hr    2626 embryo 16-18hr    676 embryo 18-20hr    268 embryo 20-22hr    80 embryo 22-24hr    106 larva L1    198 larva L2    1645 larva L3 12hr old    1086 larva L3 puffstage 1-2    1653 larva L3 puffstage 3-6    2441 larva L3 puffstage 7-9    2441 white prepupae new    2730 white prepupae 12hr    1216 white prepupae 24hr    3286 pupae 2d postWPP    8106 pupae 3d postWPP    622 pupae 4d postWPP    216 adult male 01day    189 adult male 05day    182 adult male 30day    210 adult female 01day    126 adult female 05day    63 adult female 30day    59 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    32 embryo 02-04hr    326 embryo 04-06hr    1489 embryo 06-08hr    2133 embryo 08-10hr    2728 embryo 10-12hr    4513 embryo 12-14hr    4468 embryo 14-16hr    2626 embryo 16-18hr    676 embryo 18-20hr    268 embryo 20-22hr    80 embryo 22-24hr    106 larva L1    198 larva L2    1645 larva L3 12hr old    1086 larva L3 puffstage 1-2    1653 larva L3 puffstage 3-6    2441 larva L3 puffstage 7-9    2441 white prepupae new    2730 white prepupae 12hr    1216 white prepupae 24hr    3286 pupae 2d postWPP    8106 pupae 3d postWPP    622 pupae 4d postWPP    216 adult male 01day    189 adult male 05day    182 adult male 30day    210 adult female 01day    126 adult female 05day    63 adult female 30day    59 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0038660 expression level Developmental Stage   Expression Level embryo 00-02hr    32 embryo 02-04hr    326 embryo 04-06hr    1489 embryo 06-08hr    2133 embryo 08-10hr    2728 embryo 10-12hr    4513 embryo 12-14hr    4468 embryo 14-16hr    2626 embryo 16-18hr    676 embryo 18-20hr    268 embryo 20-22hr    80 embryo 22-24hr    106 larva L1    198 larva L2    1645 larva L3 12hr old    1086 larva L3 puffstage 1-2    1653 larva L3 puffstage 3-6    2441 larva L3 puffstage 7-9    2441 white prepupae new    2730 white prepupae 12hr    1216 white prepupae 24hr    3286 pupae 2d postWPP    8106 pupae 3d postWPP    622 pupae 4d postWPP    216 adult male 01day    189 adult male 05day    182 adult male 30day    210 adult female 01day    126 adult female 05day    63 adult female 30day    59 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    32 embryo 02-04hr  (326) embryo 04-06hr  (1489) embryo 06-08hr  (2133) embryo 08-10hr  (2728) embryo 10-12hr  (4513) embryo 12-14hr  (4468) embryo 14-16hr  (2626) embryo 16-18hr  (676) embryo 18-20hr  (268) embryo 20-22hr    80 embryo 22-24hr  106 larva L1  (198) larva L2  (1645) larva L3 12hr old  (1086) larva L3 puffstage 1-2  (1653) larva L3 puffstage 3-6  (2441) larva L3 puffstage 7-9  (2441) white prepupae new  (2730) white prepupae 12hr  (1216) white prepupae 24hr  (3286) pupae 2d postWPP  (8106) pupae 3d postWPP  (622) pupae 4d postWPP  (216) adult male 01day  (189) adult male 05day  (182) adult male 30day  (210) adult female 01day  126 adult female 05day    63 adult female 30day    59 Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    32 embryo 02-04hr    326 embryo 04-06hr  1489 embryo 06-08hr  2133 embryo 08-10hr  (2728) embryo 10-12hr  (4513) embryo 12-14hr  (4468) embryo 14-16hr  (2626) embryo 16-18hr    676 embryo 18-20hr    268 embryo 20-22hr    80 embryo 22-24hr    106 larva L1    198 larva L2  1645 larva L3 12hr old    1086 larva L3 puffstage 1-2  1653 larva L3 puffstage 3-6  2441 larva L3 puffstage 7-9  2441 white prepupae new  (2730) white prepupae 12hr    1216 white prepupae 24hr  (3286) pupae 2d postWPP  (8106) pupae 3d postWPP    622 pupae 4d postWPP    216 adult male 01day    189 adult male 05day    182 adult male 30day    210 adult female 01day    126 adult female 05day    63 adult female 30day    59 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    32 embryo 02-04hr    326 embryo 04-06hr    1489 embryo 06-08hr    2133 embryo 08-10hr    2728 embryo 10-12hr    4513 embryo 12-14hr    4468 embryo 14-16hr    2626 embryo 16-18hr    676 embryo 18-20hr    268 embryo 20-22hr    80 embryo 22-24hr    106 larva L1    198 larva L2    1645 larva L3 12hr old    1086 larva L3 puffstage 1-2    1653 larva L3 puffstage 3-6    2441 larva L3 puffstage 7-9    2441 white prepupae new    2730 white prepupae 12hr    1216 white prepupae 24hr    3286 pupae 2d postWPP    8106 pupae 3d postWPP    622 pupae 4d postWPP    216 adult male 01day    189 adult male 05day    182 adult male 30day    210 adult female 01day    126 adult female 05day    63 adult female 30day    59 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    32 embryo 02-04hr    326 embryo 04-06hr    1489 embryo 06-08hr    2133 embryo 08-10hr    2728 embryo 10-12hr    4513 embryo 12-14hr    4468 embryo 14-16hr    2626 embryo 16-18hr    676 embryo 18-20hr    268 embryo 20-22hr    80 embryo 22-24hr    106 larva L1    198 larva L2    1645 larva L3 12hr old    1086 larva L3 puffstage 1-2    1653 larva L3 puffstage 3-6    2441 larva L3 puffstage 7-9    2441 white prepupae new    2730 white prepupae 12hr    1216 white prepupae 24hr    3286 pupae 2d postWPP    8106 pupae 3d postWPP    622 pupae 4d postWPP    216 adult male 01day    189 adult male 05day    182 adult male 30day    210 adult female 01day    126 adult female 05day    63 adult female 30day    59 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0038660    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0038660 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval fat body. Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval hindgut, larval trachea, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0038660 expression level Tissue   Expression Level Larval Central Nervous System    111.325 Larval Midgut    29.1 Larval Hindgut    136.4 Larval Malpighian Tubules    48.9 Larval Fat Body    770.8 Larval Salivary Gland    36.9 Larval Trachea    495.225 Larval Carcass    292.075 Adult Head    53.7 Adult Eye    20.375 Adult Brain    82.7 Adult Thoracic-Abdominal Ganglion    95.3 Adult Crop    11.7 Adult Midgut    15.4 Adult Hindgut    24.5 Adult Malpighian Tubules no informative data Adult Fat Body    17.8 Adult Salivary Gland    34.2 Adult Heart    33.525 Adult VirginFemale Spermatheca    21.3 Adult InseminatedFemale Spermatheca    35.6 Adult Ovary    7.5 Adult Testis    14.1 Adult Male Accessory Gland    40.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    111.325 Larval Midgut    29.1 Larval Hindgut    136.4 Larval Malpighian Tubules    48.9 Larval Fat Body  (770.8) Larval Salivary Gland    36.9 Larval Trachea    495.225 Larval Carcass    292.075 Adult Head    53.7 Adult Eye    20.375 Adult Brain    82.7 Adult Thoracic-Abdominal Ganglion    95.3 Adult Crop    11.7 Adult Midgut    15.4 Adult Hindgut    24.5 Adult Malpighian Tubules no informative data Adult Fat Body    17.8 Adult Salivary Gland    34.2 Adult Heart    33.525 Adult VirginFemale Spermatheca    21.3 Adult InseminatedFemale Spermatheca    35.6 Adult Ovary    7.5 Adult Testis    14.1 Adult Male Accessory Gland    40.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    111.325 Larval Midgut    29.1 Larval Hindgut    136.4 Larval Malpighian Tubules    48.9 Larval Fat Body    770.8 Larval Salivary Gland    36.9 Larval Trachea    495.225 Larval Carcass    292.075 Adult Head    53.7 Adult Eye    20.375 Adult Brain    82.7 Adult Thoracic-Abdominal Ganglion    95.3 Adult Crop    11.7 Adult Midgut    15.4 Adult Hindgut    24.5 Adult Malpighian Tubules no informative data Adult Fat Body    17.8 Adult Salivary Gland    34.2 Adult Heart    33.525 Adult VirginFemale Spermatheca    21.3 Adult InseminatedFemale Spermatheca    35.6 Adult Ovary    7.5 Adult Testis    14.1 Adult Male Accessory Gland    40.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    111.325 Larval Midgut    29.1 Larval Hindgut    136.4 Larval Malpighian Tubules    48.9 Larval Fat Body    770.8 Larval Salivary Gland    36.9 Larval Trachea    495.225 Larval Carcass    292.075 Adult Head    53.7 Adult Eye    20.375 Adult Brain    82.7 Adult Thoracic-Abdominal Ganglion    95.3 Adult Crop    11.7 Adult Midgut    15.4 Adult Hindgut    24.5 Adult Malpighian Tubules no informative data Adult Fat Body    17.8 Adult Salivary Gland    34.2 Adult Heart    33.525 Adult VirginFemale Spermatheca    21.3 Adult InseminatedFemale Spermatheca    35.6 Adult Ovary    7.5 Adult Testis    14.1 Adult Male Accessory Gland    40.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0038660 expression level Tissue   Expression Level Larval Central Nervous System    111.325 Larval Midgut    29.1 Larval Hindgut    136.4 Larval Malpighian Tubules    48.9 Larval Fat Body    770.8 Larval Salivary Gland    36.9 Larval Trachea    495.225 Larval Carcass    292.075 Adult Head    53.7 Adult Eye    20.375 Adult Brain    82.7 Adult Thoracic-Abdominal Ganglion    95.3 Adult Crop    11.7 Adult Midgut    15.4 Adult Hindgut    24.5 Adult Malpighian Tubules no informative data Adult Fat Body    17.8 Adult Salivary Gland    34.2 Adult Heart    33.525 Adult VirginFemale Spermatheca    21.3 Adult InseminatedFemale Spermatheca    35.6 Adult Ovary    7.5 Adult Testis    14.1 Adult Male Accessory Gland    40.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    111.325 Larval Midgut    29.1 Larval Hindgut    136.4 Larval Malpighian Tubules    48.9 Larval Fat Body  770.8 Larval Salivary Gland    36.9 Larval Trachea    495.225 Larval Carcass    292.075 Adult Head    53.7 Adult Eye    20.375 Adult Brain    82.7 Adult Thoracic-Abdominal Ganglion    95.3 Adult Crop    11.7 Adult Midgut    15.4 Adult Hindgut    24.5 Adult Malpighian Tubules no informative data Adult Fat Body    17.8 Adult Salivary Gland    34.2 Adult Heart    33.525 Adult VirginFemale Spermatheca    21.3 Adult InseminatedFemale Spermatheca    35.6 Adult Ovary    7.5 Adult Testis    14.1 Adult Male Accessory Gland    40.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    111.325 Larval Midgut    29.1 Larval Hindgut    136.4 Larval Malpighian Tubules    48.9 Larval Fat Body    770.8 Larval Salivary Gland    36.9 Larval Trachea    495.225 Larval Carcass    292.075 Adult Head    53.7 Adult Eye    20.375 Adult Brain    82.7 Adult Thoracic-Abdominal Ganglion    95.3 Adult Crop    11.7 Adult Midgut    15.4 Adult Hindgut    24.5 Adult Malpighian Tubules no informative data Adult Fat Body    17.8 Adult Salivary Gland    34.2 Adult Heart    33.525 Adult VirginFemale Spermatheca    21.3 Adult InseminatedFemale Spermatheca    35.6 Adult Ovary    7.5 Adult Testis    14.1 Adult Male Accessory Gland    40.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    111.325 Larval Midgut    29.1 Larval Hindgut    136.4 Larval Malpighian Tubules    48.9 Larval Fat Body    770.8 Larval Salivary Gland    36.9 Larval Trachea    495.225 Larval Carcass    292.075 Adult Head    53.7 Adult Eye    20.375 Adult Brain    82.7 Adult Thoracic-Abdominal Ganglion    95.3 Adult Crop    11.7 Adult Midgut    15.4 Adult Hindgut    24.5 Adult Malpighian Tubules no informative data Adult Fat Body    17.8 Adult Salivary Gland    34.2 Adult Heart    33.525 Adult VirginFemale Spermatheca    21.3 Adult InseminatedFemale Spermatheca    35.6 Adult Ovary    7.5 Adult Testis    14.1 Adult Male Accessory Gland    40.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules no informative data Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    53.7   NA  Eye    20.375   NA  Brain    82.7   111.325  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    95.3   NA  Crop    11.7   29.1  Midgut    15.4   136.4  Hindgut    24.5   48.9  Malpighian Tubules    no informative data   770.8  Fat Body    17.8   36.9  Salivary Gland    34.2   NA  Heart    33.525   495.225  Trachea    NA   NA  VirginFemale Spermatheca    21.3   NA  InseminatedFemale Spermatheca    35.6   NA  Ovary    7.5   NA  Testis    14.1   NA  Male Accessory Gland    40.4   292.075  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_25
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038660 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14291-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG14291 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG14291GD1578 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG14291 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG14291 Class Mutagen Stocks Known lesion CG14291GD1578 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG14291KK101207 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6181 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD1578} NA P{KK101207} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{SUPor-P}KG01422 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
N-sulfoglucosamine sulfohydrolase activity inferred from sequence or structural similarity with UniProtKB:P51688 (FlyBase, 1992-) sulfuric ester hydrolase activity inferred from electronic annotation with InterPro:IPR000917 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
metabolic process inferred from electronic annotation with InterPro:IPR000917, InterPro:IPR017849, InterPro:IPR017850 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG14291 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0038660
Orthologs
Genome-wide drosophilid orthologs	Dana\GF23012 Dere\GG16284 Dgri\GH18737 Dmoj\GI24623 Dper\GL24108 Dpse\GA12883 Dsec\GM18674 Dsim\GD20144 Dvir\GJ14185 Dwil\GK22437 Dyak\GE25163
Curated drosophilid orthologs	Dere\GG16284   Dpse\GA12883   Dvir\GJ14185   Dwil\GK22437
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL010437-PA Aedes aegypti (mosquito) AGAP004205-PA Anopheles gambiae (mosquito) XP_623278.1 Apis mellifera (honey bee) 118993 Branchiostoma floridae (lancelet) 287628 Branchiostoma floridae (lancelet) BGIBMGA005529-PA Bombyx mori (silk worm) ENSBTAP00000020308 Bos taurus (bovine) ENSCAFP00000008421 Canis familiaris (dog) ENSCINP00000018523 Ciona intestinalis (sea squirt) ENSCPOP00000004673 Cavia porcellus (guinea pig) ENSCSAVP00000003472 Ciona savignyi (sedentary tunicate) 155123 Capitella spl (polychaete worm) 327208 Daphnia pulex (daphnia) ENSDARP00000063146 Danio rerio (zebra fish) ENSECAP00000003441 Equus caballus (horse) ENSGACP00000025132 Gymnopilus aculeatus (mushroom) ENSP00000314606 Homo sapiens (human) 230682 Lottia gigantea (owl limpet) ENSMODP00000002707 Monodelphis domestica (gray opossum) ENSMMUP00000003811 Macaca mulatta (rhesus monkey) ENSMUSP00000005173 Mus musculus (house mouse) 235706 Nematostella vectensis (starlet anemone) XP_001605082.1 Nasonia vitripennis (wasp) ENSORLP00000015131 Oryzias latipes (japanese killifish) PHUM003132-PA Pediculus humanus (human body louse) ENSPPYP00000009781 Pongo pygmaeus (orangutan) ENSPTRP00000016571 Pan troglodytes (chimpanzee) XP_001175998.1 Strongylocentrotus purpuratus (purple sea urchin) XP_970679.1 Tribolium castaneum (red flour beetle) ENSTNIP00000017066 Tetraodon nigroviridis (green spotted pufferfish) 2824 Thalassiosira pseudonana (marine diatom) ENSTRUP00000028966 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000042530 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17829 NV16394 LH12766 ISCW005581 FBgn0242249 FBgn0064298 FBgn0086440 FBgn0191623 FBgn0173580 JGI_V11_327208 FBgn0064440 FBgn0161698 FBgn0147345 FBgn0126204 FBgn0064645 FBgn0100006 CPIJ010201 BGIBMGA005529 GB14747 AGAP004205 AAEL010437 PHUM328420 GLEAN_06555
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v107384 P{KK101207}VIE-260B v16897 w1118; P{GD1578}v16897
Genomic Clones ( 1 )
	BACR44N12 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 12 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE63280
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RE07307 RE07319 RE12269 RE17807 RE18011 RE21009 RE37056 RE44822
Other clones	12488 82951 EK216639
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0038660 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42266
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_142503 RefSeq (Proteins) • NP_650760 DDBJ / EMBL / GenBank • AAF55607 AAL49191 AY071569 BI375460 Entrez Gene - A searchable database of RefSeq genes. • 42266 UniProtKB/TrEMBL • Q9VE24
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Sulfatase (IPR000917) Alkaline phosphatase-like, alpha/beta/alpha (IPR017849) Alkaline-phosphatase-like, core domain (IPR017850) Sulfatase, conserved site (IPR024607)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0038660 DRSC - Results from RNAi screens. • FBgn0038660 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038660 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14291-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0038660 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42266 InParanoid A subset of ortholog calls from InParanoid. • AAEL010437-PA Aedes aegypti (mosquito) AGAP004205-PA Anopheles gambiae (mosquito) XP_623278.1 Apis mellifera (honey bee) 118993 Branchiostoma floridae (lancelet) 287628 Branchiostoma floridae (lancelet) BGIBMGA005529-PA Bombyx mori (silk worm) ENSBTAP00000020308 Bos taurus (bovine) ENSCAFP00000008421 Canis familiaris (dog) ENSCINP00000018523 Ciona intestinalis (sea squirt) ENSCPOP00000004673 Cavia porcellus (guinea pig) ENSCSAVP00000003472 Ciona savignyi (sedentary tunicate) 155123 Capitella spl (polychaete worm) 327208 Daphnia pulex (daphnia) ENSDARP00000063146 Danio rerio (zebra fish) ENSECAP00000003441 Equus caballus (horse) ENSGACP00000025132 Gymnopilus aculeatus (mushroom) ENSP00000314606 Homo sapiens (human) 230682 Lottia gigantea (owl limpet) ENSMODP00000002707 Monodelphis domestica (gray opossum) ENSMMUP00000003811 Macaca mulatta (rhesus monkey) ENSMUSP00000005173 Mus musculus (house mouse) 235706 Nematostella vectensis (starlet anemone) XP_001605082.1 Nasonia vitripennis (wasp) ENSORLP00000015131 Oryzias latipes (japanese killifish) PHUM003132-PA Pediculus humanus (human body louse) ENSPPYP00000009781 Pongo pygmaeus (orangutan) ENSPTRP00000016571 Pan troglodytes (chimpanzee) XP_001175998.1 Strongylocentrotus purpuratus (purple sea urchin) XP_970679.1 Tribolium castaneum (red flour beetle) ENSTNIP00000017066 Tetraodon nigroviridis (green spotted pufferfish) 2824 Thalassiosira pseudonana (marine diatom) ENSTRUP00000028966 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000042530 Xenopus tropicalis (frog) modMine - Data generated by the modENCODE project. • FBgn0038660 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17829 NV16394 LH12766 ISCW005581 FBgn0242249 FBgn0064298 FBgn0086440 FBgn0191623 FBgn0173580 JGI_V11_327208 FBgn0064440 FBgn0161698 FBgn0147345 FBgn0126204 FBgn0064645 FBgn0100006 CPIJ010201 BGIBMGA005529 GB14747 AGAP004205 AAEL010437 PHUM328420 GLEAN_06555
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG14291 (Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 14 )
Research paper	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Inlow and Restifo, 2004, Genetics 166(2): 835--881 Molecular and comparative genetics of mental retardation. [FBrf0174714]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Curated genome annotation	Evangelista, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126663]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]