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Gene Dmel\CG5835

General Information
Symbol	Dmel\CG5835	Species	D. melanogaster
Name		Annotation symbol	CG5835
Feature type	protein_coding_gene	FlyBase ID	FBgn0038682
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	91F4-91F4	Sequence location	3R:14,974,354..14,979,408 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG5835 (FBgn0038682). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, larval/adult hindgut, adult Malpighian tubules, adult salivary gland, larval trachea, adult spermathecae, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1627354_at aligns to a genomic region shared by exons of 2 FlyBase-annotated genes; hence it is impossible to interpret the expression pattern and levels of CG5835 expression signal. See the GBrowse view of CG5835 to determine the overlapping gene(s). Gene sequence location is 3R:14974354..14979408.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 91F4-91F4   Limits computationally determined from genome sequence between P{PZ}cdi07013&P{lacW}nosj3B6 and P{PZ}l(3)0334603346
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG5835 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.47
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG5835-RA FBtr0083751  NM_142528   1344   237
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG5835-PA   FBpp0083165   25.8   237   4.10     NP_650785   AAF55638
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA246373   AE014297 AAF55638   AY058409   AY089695 AAL90433   BG637823   BI213375   BI237136   BI237542   BI240367   BI358214   BI579074   BI604745   BP550748   BP550749   BT088859   CK661724   CL525903   CO189024   CO344161   CZ485684   CZ485685   EC254641   EC256271   GH747933   GH749486   GH759487   GH774660   GH774885   GH775608   GH778520   GH780629   GH781759   GH793412   GH794588   GH794678   GH795562   GH798220   GH798718   GH801935   GH802209   GH804391   GH812984   GH813886   GH830843   GH833082   GH837661   GH837985   GH838104   GH842171   GH843808   GH846262   GH848152   GH849953   GH857639   GH860712   GH863207   GH869186   GH869260   GH869477   GH870788   GH872638   GH875474   GH882891   GH883558   GH884690   GH886283   GH886947   GH887945   GH889043   GH892248   GH892962   GH893054   GH895519   GH896589   GH901277   GH902712   GH903398   GH905929   GH913812   GH917931   GH918560   GH919340   GH921502   GH931238   GH935049   GH935855   GH936241   GH936303   GH936684   GH937409
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VDZ9 Q8SXD8
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, larval/adult hindgut, adult Malpighian tubules, adult salivary gland, larval trachea, adult spermathecae, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    14.45 Larval Midgut    794.6 Larval Hindgut    163.5 Larval Malpighian Tubules    90.1 Larval Fat Body    26.2 Larval Salivary Gland    16.8 Larval Trachea    290.75 Larval Carcass    204.625 Adult Head    255.5 Adult Eye    143.725 Adult Brain    182.5 Adult Thoracic-Abdominal Ganglion    267.7 Adult Crop    98.1 Adult Midgut    1253.4 Adult Hindgut    210.5 Adult Malpighian Tubules    159.9 Adult Fat Body    15.5 Adult Salivary Gland    317.3 Adult Heart    19.2 Adult VirginFemale Spermatheca    114.5 Adult InseminatedFemale Spermatheca    133.3 Adult Ovary    38.7 Adult Testis    34 Adult Male Accessory Gland    67 Adult Carcass    298.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    14.45 Larval Midgut  (794.6) Larval Hindgut    163.5 Larval Malpighian Tubules    90.1 Larval Fat Body    26.2 Larval Salivary Gland    16.8 Larval Trachea    290.75 Larval Carcass    204.625 Adult Head    255.5 Adult Eye    143.725 Adult Brain    182.5 Adult Thoracic-Abdominal Ganglion    267.7 Adult Crop    98.1 Adult Midgut  (1253.4) Adult Hindgut    210.5 Adult Malpighian Tubules    159.9 Adult Fat Body    15.5 Adult Salivary Gland    317.3 Adult Heart    19.2 Adult VirginFemale Spermatheca    114.5 Adult InseminatedFemale Spermatheca    133.3 Adult Ovary    38.7 Adult Testis    34 Adult Male Accessory Gland    67 Adult Carcass    298.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    14.45 Larval Midgut    794.6 Larval Hindgut    163.5 Larval Malpighian Tubules    90.1 Larval Fat Body    26.2 Larval Salivary Gland    16.8 Larval Trachea    290.75 Larval Carcass    204.625 Adult Head    255.5 Adult Eye    143.725 Adult Brain    182.5 Adult Thoracic-Abdominal Ganglion    267.7 Adult Crop    98.1 Adult Midgut  (1253.4) Adult Hindgut    210.5 Adult Malpighian Tubules    159.9 Adult Fat Body    15.5 Adult Salivary Gland    317.3 Adult Heart    19.2 Adult VirginFemale Spermatheca    114.5 Adult InseminatedFemale Spermatheca    133.3 Adult Ovary    38.7 Adult Testis    34 Adult Male Accessory Gland    67 Adult Carcass    298.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    14.45 Larval Midgut    794.6 Larval Hindgut    163.5 Larval Malpighian Tubules    90.1 Larval Fat Body    26.2 Larval Salivary Gland    16.8 Larval Trachea    290.75 Larval Carcass    204.625 Adult Head    255.5 Adult Eye    143.725 Adult Brain    182.5 Adult Thoracic-Abdominal Ganglion    267.7 Adult Crop    98.1 Adult Midgut    1253.4 Adult Hindgut    210.5 Adult Malpighian Tubules    159.9 Adult Fat Body    15.5 Adult Salivary Gland    317.3 Adult Heart    19.2 Adult VirginFemale Spermatheca    114.5 Adult InseminatedFemale Spermatheca    133.3 Adult Ovary    38.7 Adult Testis    34 Adult Male Accessory Gland    67 Adult Carcass    298.4 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    14.45 Larval Midgut    794.6 Larval Hindgut    163.5 Larval Malpighian Tubules    90.1 Larval Fat Body    26.2 Larval Salivary Gland    16.8 Larval Trachea    290.75 Larval Carcass    204.625 Adult Head    255.5 Adult Eye    143.725 Adult Brain    182.5 Adult Thoracic-Abdominal Ganglion    267.7 Adult Crop    98.1 Adult Midgut    1253.4 Adult Hindgut    210.5 Adult Malpighian Tubules    159.9 Adult Fat Body    15.5 Adult Salivary Gland    317.3 Adult Heart    19.2 Adult VirginFemale Spermatheca    114.5 Adult InseminatedFemale Spermatheca    133.3 Adult Ovary    38.7 Adult Testis    34 Adult Male Accessory Gland    67 Adult Carcass    298.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    14.45 Larval Midgut  794.6 Larval Hindgut    163.5 Larval Malpighian Tubules    90.1 Larval Fat Body    26.2 Larval Salivary Gland    16.8 Larval Trachea    290.75 Larval Carcass    204.625 Adult Head    255.5 Adult Eye    143.725 Adult Brain    182.5 Adult Thoracic-Abdominal Ganglion    267.7 Adult Crop    98.1 Adult Midgut  (1253.4) Adult Hindgut    210.5 Adult Malpighian Tubules    159.9 Adult Fat Body    15.5 Adult Salivary Gland    317.3 Adult Heart    19.2 Adult VirginFemale Spermatheca    114.5 Adult InseminatedFemale Spermatheca    133.3 Adult Ovary    38.7 Adult Testis    34 Adult Male Accessory Gland    67 Adult Carcass    298.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    14.45 Larval Midgut    794.6 Larval Hindgut    163.5 Larval Malpighian Tubules    90.1 Larval Fat Body    26.2 Larval Salivary Gland    16.8 Larval Trachea    290.75 Larval Carcass    204.625 Adult Head    255.5 Adult Eye    143.725 Adult Brain    182.5 Adult Thoracic-Abdominal Ganglion    267.7 Adult Crop    98.1 Adult Midgut  1253.4 Adult Hindgut    210.5 Adult Malpighian Tubules    159.9 Adult Fat Body    15.5 Adult Salivary Gland    317.3 Adult Heart    19.2 Adult VirginFemale Spermatheca    114.5 Adult InseminatedFemale Spermatheca    133.3 Adult Ovary    38.7 Adult Testis    34 Adult Male Accessory Gland    67 Adult Carcass    298.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    14.45 Larval Midgut    794.6 Larval Hindgut    163.5 Larval Malpighian Tubules    90.1 Larval Fat Body    26.2 Larval Salivary Gland    16.8 Larval Trachea    290.75 Larval Carcass    204.625 Adult Head    255.5 Adult Eye    143.725 Adult Brain    182.5 Adult Thoracic-Abdominal Ganglion    267.7 Adult Crop    98.1 Adult Midgut    1253.4 Adult Hindgut    210.5 Adult Malpighian Tubules    159.9 Adult Fat Body    15.5 Adult Salivary Gland    317.3 Adult Heart    19.2 Adult VirginFemale Spermatheca    114.5 Adult InseminatedFemale Spermatheca    133.3 Adult Ovary    38.7 Adult Testis    34 Adult Male Accessory Gland    67 Adult Carcass    298.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    255.5   NA  Eye    143.725   NA  Brain    182.5   14.45  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    267.7   NA  Crop    98.1   794.6  Midgut    1253.4   163.5  Hindgut    210.5   90.1  Malpighian Tubules    159.9   26.2  Fat Body    15.5   16.8  Salivary Gland    317.3   NA  Heart    19.2   290.75  Trachea    NA   NA  VirginFemale Spermatheca    114.5   NA  InseminatedFemale Spermatheca    133.3   NA  Ovary    38.7   NA  Testis    34   NA  Male Accessory Gland    67   204.625  Carcass    298.4 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    3 central nervous system, pupae P8    1 head, virgin 1-day female    9 head, virgin 4-day female    8 head, virgin 20-day female    9 head, mated 1-day female    9 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    14 head, mated 4-day male    14 head, mated 20-day male    24 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    32 digestive system, 1-day adult    45 digestive system, 4-day adult    32 digestive system, 20-day adult    38 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    19 carcass, 1-day adult    16 carcass, 4-day adult    15 carcass, 20-day adult    18 ovary, virgin 4-day female    3 ovary, mated 4-day female    2 testis, mated 4-day male    6 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    3 central nervous system, pupae P8    1 head, virgin 1-day female    9 head, virgin 4-day female    8 head, virgin 20-day female    9 head, mated 1-day female    9 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    14 head, mated 4-day male    14 head, mated 20-day male    24 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    6 digestive system, larvae L3 wandering  (32) digestive system, 1-day adult  (45) digestive system, 4-day adult  (32) digestive system, 20-day adult  (38) fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    19 carcass, 1-day adult    16 carcass, 4-day adult    15 carcass, 20-day adult    18 ovary, virgin 4-day female    3 ovary, mated 4-day female    2 testis, mated 4-day male    6 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    3 central nervous system, pupae P8    1 head, virgin 1-day female    9 head, virgin 4-day female    8 head, virgin 20-day female    9 head, mated 1-day female    9 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    14 head, mated 4-day male    14 head, mated 20-day male    24 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    32 digestive system, 1-day adult    45 digestive system, 4-day adult    32 digestive system, 20-day adult    38 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    19 carcass, 1-day adult    16 carcass, 4-day adult    15 carcass, 20-day adult    18 ovary, virgin 4-day female    3 ovary, mated 4-day female    2 testis, mated 4-day male    6 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    3 central nervous system, pupae P8    1 head, virgin 1-day female    9 head, virgin 4-day female    8 head, virgin 20-day female    9 head, mated 1-day female    9 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    14 head, mated 4-day male    14 head, mated 20-day male    24 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    32 digestive system, 1-day adult    45 digestive system, 4-day adult    32 digestive system, 20-day adult    38 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    19 carcass, 1-day adult    16 carcass, 4-day adult    15 carcass, 20-day adult    18 ovary, virgin 4-day female    3 ovary, mated 4-day female    2 testis, mated 4-day male    6 accessory gland, mated 4-day male    6 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    3 central nervous system, pupae P8    1 head, virgin 1-day female    9 head, virgin 4-day female    8 head, virgin 20-day female    9 head, mated 1-day female    9 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    14 head, mated 4-day male    14 head, mated 20-day male    24 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    32 digestive system, 1-day adult    45 digestive system, 4-day adult    32 digestive system, 20-day adult    38 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    19 carcass, 1-day adult    16 carcass, 4-day adult    15 carcass, 20-day adult    18 ovary, virgin 4-day female    3 ovary, mated 4-day female    2 testis, mated 4-day male    6 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    3 central nervous system, pupae P8    1 head, virgin 1-day female    9 head, virgin 4-day female    8 head, virgin 20-day female    9 head, mated 1-day female    9 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    14 head, mated 4-day male    14 head, mated 20-day male    24 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    6 digestive system, larvae L3 wandering  32 digestive system, 1-day adult  (45) digestive system, 4-day adult  32 digestive system, 20-day adult  (38) fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    19 carcass, 1-day adult    16 carcass, 4-day adult    15 carcass, 20-day adult    18 ovary, virgin 4-day female    3 ovary, mated 4-day female    2 testis, mated 4-day male    6 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    3 central nervous system, pupae P8    1 head, virgin 1-day female    9 head, virgin 4-day female    8 head, virgin 20-day female    9 head, mated 1-day female    9 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    14 head, mated 4-day male    14 head, mated 20-day male    24 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    32 digestive system, 1-day adult    45 digestive system, 4-day adult    32 digestive system, 20-day adult    38 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    19 carcass, 1-day adult    16 carcass, 4-day adult    15 carcass, 20-day adult    18 ovary, virgin 4-day female    3 ovary, mated 4-day female    2 testis, mated 4-day male    6 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    3 central nervous system, pupae P8    1 head, virgin 1-day female    9 head, virgin 4-day female    8 head, virgin 20-day female    9 head, mated 1-day female    9 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    14 head, mated 4-day male    14 head, mated 20-day male    24 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    32 digestive system, 1-day adult    45 digestive system, 4-day adult    32 digestive system, 20-day adult    38 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    19 carcass, 1-day adult    16 carcass, 4-day adult    15 carcass, 20-day adult    18 ovary, virgin 4-day female    3 ovary, mated 4-day female    2 testis, mated 4-day male    6 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed during early pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    3 embryo 10-12hr    18 embryo 12-14hr    22 embryo 14-16hr    16 embryo 16-18hr    14 embryo 18-20hr    16 embryo 20-22hr    28 embryo 22-24hr    30 larva L1    17 larva L2    32 larva L3 12hr old    26 larva L3 puffstage 1-2    31 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    30 white prepupae new    122 white prepupae 12hr    137 white prepupae 24hr    45 pupae 2d postWPP    27 pupae 3d postWPP    10 pupae 4d postWPP    17 adult male 01day    26 adult male 05day    25 adult male 30day    23 adult female 01day    23 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    3 embryo 10-12hr    18 embryo 12-14hr    22 embryo 14-16hr    16 embryo 16-18hr    14 embryo 18-20hr    16 embryo 20-22hr  (28) embryo 22-24hr  (30) larva L1    17 larva L2  (32) larva L3 12hr old  26 larva L3 puffstage 1-2  (31) larva L3 puffstage 3-6    22 larva L3 puffstage 7-9  (30) white prepupae new  (122) white prepupae 12hr  (137) white prepupae 24hr  (45) pupae 2d postWPP  (27) pupae 3d postWPP    10 pupae 4d postWPP    17 adult male 01day  26 adult male 05day    25 adult male 30day    23 adult female 01day    23 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    3 embryo 10-12hr    18 embryo 12-14hr    22 embryo 14-16hr    16 embryo 16-18hr    14 embryo 18-20hr    16 embryo 20-22hr    28 embryo 22-24hr    30 larva L1    17 larva L2    32 larva L3 12hr old    26 larva L3 puffstage 1-2    31 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    30 white prepupae new  (122) white prepupae 12hr  (137) white prepupae 24hr    45 pupae 2d postWPP    27 pupae 3d postWPP    10 pupae 4d postWPP    17 adult male 01day    26 adult male 05day    25 adult male 30day    23 adult female 01day    23 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    3 embryo 10-12hr    18 embryo 12-14hr    22 embryo 14-16hr    16 embryo 16-18hr    14 embryo 18-20hr    16 embryo 20-22hr    28 embryo 22-24hr    30 larva L1    17 larva L2    32 larva L3 12hr old    26 larva L3 puffstage 1-2    31 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    30 white prepupae new    122 white prepupae 12hr    137 white prepupae 24hr    45 pupae 2d postWPP    27 pupae 3d postWPP    10 pupae 4d postWPP    17 adult male 01day    26 adult male 05day    25 adult male 30day    23 adult female 01day    23 adult female 05day    15 adult female 30day    16 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    3 embryo 10-12hr    18 embryo 12-14hr    22 embryo 14-16hr    16 embryo 16-18hr    14 embryo 18-20hr    16 embryo 20-22hr    28 embryo 22-24hr    30 larva L1    17 larva L2    32 larva L3 12hr old    26 larva L3 puffstage 1-2    31 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    30 white prepupae new    122 white prepupae 12hr    137 white prepupae 24hr    45 pupae 2d postWPP    27 pupae 3d postWPP    10 pupae 4d postWPP    17 adult male 01day    26 adult male 05day    25 adult male 30day    23 adult female 01day    23 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    3 embryo 10-12hr    18 embryo 12-14hr    22 embryo 14-16hr    16 embryo 16-18hr    14 embryo 18-20hr    16 embryo 20-22hr  28 embryo 22-24hr  30 larva L1    17 larva L2  32 larva L3 12hr old  26 larva L3 puffstage 1-2  31 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9  30 white prepupae new  (122) white prepupae 12hr  (137) white prepupae 24hr  (45) pupae 2d postWPP  27 pupae 3d postWPP    10 pupae 4d postWPP    17 adult male 01day  26 adult male 05day    25 adult male 30day    23 adult female 01day    23 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    3 embryo 10-12hr    18 embryo 12-14hr    22 embryo 14-16hr    16 embryo 16-18hr    14 embryo 18-20hr    16 embryo 20-22hr    28 embryo 22-24hr    30 larva L1    17 larva L2    32 larva L3 12hr old    26 larva L3 puffstage 1-2    31 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    30 white prepupae new  122 white prepupae 12hr  137 white prepupae 24hr    45 pupae 2d postWPP    27 pupae 3d postWPP    10 pupae 4d postWPP    17 adult male 01day    26 adult male 05day    25 adult male 30day    23 adult female 01day    23 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    3 embryo 10-12hr    18 embryo 12-14hr    22 embryo 14-16hr    16 embryo 16-18hr    14 embryo 18-20hr    16 embryo 20-22hr    28 embryo 22-24hr    30 larva L1    17 larva L2    32 larva L3 12hr old    26 larva L3 puffstage 1-2    31 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    30 white prepupae new    122 white prepupae 12hr    137 white prepupae 24hr    45 pupae 2d postWPP    27 pupae 3d postWPP    10 pupae 4d postWPP    17 adult male 01day    26 adult male 05day    25 adult male 30day    23 adult female 01day    23 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    4 Schneider line 2 Sg4    3 embryonic 1182-4H    2 embryonic GM2    6 embryonic Kc167    3 embryonic S1    8 embryonic S3    11 leg disc CME L1    6 wing disc CME-W2    4 wing disc ML-DmD8    5 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    7 wing disc ML-DmD21    9 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    3 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    24 ovary fGS/OSS    7 ovary OSC    6 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    4 Schneider line 2 Sg4    3 embryonic 1182-4H    2 embryonic GM2    6 embryonic Kc167    3 embryonic S1    8 embryonic S3    11 leg disc CME L1    6 wing disc CME-W2    4 wing disc ML-DmD8    5 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    7 wing disc ML-DmD21    9 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    3 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    24 ovary fGS/OSS    7 ovary OSC    6 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    4 Schneider line 2 Sg4    3 embryonic 1182-4H    2 embryonic GM2    6 embryonic Kc167    3 embryonic S1    8 embryonic S3    11 leg disc CME L1    6 wing disc CME-W2    4 wing disc ML-DmD8    5 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    7 wing disc ML-DmD21    9 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    3 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    24 ovary fGS/OSS    7 ovary OSC    6 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    4 Schneider line 2 Sg4    3 embryonic 1182-4H    2 embryonic GM2    6 embryonic Kc167    3 embryonic S1    8 embryonic S3    11 leg disc CME L1    6 wing disc CME-W2    4 wing disc ML-DmD8    5 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    7 wing disc ML-DmD21    9 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    3 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    24 ovary fGS/OSS    7 ovary OSC    6 ovary OSS    11 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    4 Schneider line 2 Sg4    3 embryonic 1182-4H    2 embryonic GM2    6 embryonic Kc167    3 embryonic S1    8 embryonic S3    11 leg disc CME L1    6 wing disc CME-W2    4 wing disc ML-DmD8    5 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    7 wing disc ML-DmD21    9 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    3 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    24 ovary fGS/OSS    7 ovary OSC    6 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    4 Schneider line 2 Sg4    3 embryonic 1182-4H    2 embryonic GM2    6 embryonic Kc167    3 embryonic S1    8 embryonic S3    11 leg disc CME L1    6 wing disc CME-W2    4 wing disc ML-DmD8    5 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    7 wing disc ML-DmD21    9 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    3 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    24 ovary fGS/OSS    7 ovary OSC    6 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    4 Schneider line 2 Sg4    3 embryonic 1182-4H    2 embryonic GM2    6 embryonic Kc167    3 embryonic S1    8 embryonic S3    11 leg disc CME L1    6 wing disc CME-W2    4 wing disc ML-DmD8    5 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    7 wing disc ML-DmD21    9 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    3 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    24 ovary fGS/OSS    7 ovary OSC    6 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    4 Schneider line 2 Sg4    3 embryonic 1182-4H    2 embryonic GM2    6 embryonic Kc167    3 embryonic S1    8 embryonic S3    11 leg disc CME L1    6 wing disc CME-W2    4 wing disc ML-DmD8    5 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    7 wing disc ML-DmD21    9 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    3 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    24 ovary fGS/OSS    7 ovary OSC    6 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    11 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    15 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    21 Ethanol 10% 3 hrs, larvae L3    16 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    5 Caffeine 25 mg/ml 48 hrs, 4-day adult    12 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    11 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    15 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    21 Ethanol 10% 3 hrs, larvae L3    16 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    5 Caffeine 25 mg/ml 48 hrs, 4-day adult    12 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    11 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    15 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    21 Ethanol 10% 3 hrs, larvae L3    16 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    5 Caffeine 25 mg/ml 48 hrs, 4-day adult    12 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    11 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    15 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    21 Ethanol 10% 3 hrs, larvae L3    16 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    5 Caffeine 25 mg/ml 48 hrs, 4-day adult    12 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    11 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    15 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    21 Ethanol 10% 3 hrs, larvae L3    16 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    5 Caffeine 25 mg/ml 48 hrs, 4-day adult    12 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    11 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    15 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    21 Ethanol 10% 3 hrs, larvae L3    16 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    5 Caffeine 25 mg/ml 48 hrs, 4-day adult    12 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    11 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    15 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    21 Ethanol 10% 3 hrs, larvae L3    16 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    5 Caffeine 25 mg/ml 48 hrs, 4-day adult    12 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    11 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    15 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    21 Ethanol 10% 3 hrs, larvae L3    16 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    5 Caffeine 25 mg/ml 48 hrs, 4-day adult    12 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_18 mE1_20_mRNA_expression_cluster_15
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038682 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5835-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG5835EY08453 Sterility Allele fertile CG5835EY08453 Phenotype manifest in Allele
Classical Alleles ( 5 )
For All Classical Alleles Show
Allele of CG5835 Class Mutagen Stocks Known lesion CG5835A245 1 -- CG5835EY05431 P-element activity 1 -- CG5835EY08453 P-element activity 1 -- CG5835f03135 piggyBac transposase 1 -- CG5835NP7034 1 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG5835 Class Mutagen Stocks Known lesion CG5835KK111136 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6183 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{KK111136} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}CG5835EY05431 NA P{EPgy2}CG5835EY08453 NA insertion of enhancer trap binary system P{GawB}CG5835NP7034 No miscellaneous insertions PBac{5HPw+}CG5835A245 NA PBac{WH}CG5835f03135 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG5835 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 67294 DroID - A comprehensive database of gene and protein interactions. • FBgn0038682 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42296
Orthologs
OrthoDB Orthologs (14) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6CVGTH Dipteran inclusive ortholog search EOG6Z0BG3 Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6CVGTH)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG5835     Drosophila simulans   Dsim\GD20132 Y   Drosophila sechellia   Dsec\GM10045 Y   Drosophila erecta   Dere\GG16163 Y   Drosophila yakuba   Dyak\GE25150 Y   Drosophila ananassae   Dana\GF18941 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA19166 Y   Drosophila persimilis   Dper\GL23706 Y   Drosophila willistoni   Dwil\GK13238 Y   Drosophila virilis   Dvir\GJ23682 Y   Drosophila mojavensis   Dmoj\GI24056 Y   Drosophila grimshawi   Dgri\GH18478 Y
Orthologs in non-Drosophila Dipterans (EOG6Z0BG3)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL004230   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ011512
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD20132 Drosophila sechellia Dsec\GM10045 Drosophila erecta Dere\GG16163 Drosophila yakuba Dyak\GE25150 Drosophila ananassae Dana\GF18941 Drosophila pseudoobscura pseudoobscura Dpse\GA19166 Drosophila persimilis Dper\GL23706 Drosophila willistoni Dwil\GK13238 Drosophila virilis Dvir\GJ23682 Drosophila mojavensis Dmoj\GI24056 Drosophila grimshawi Dgri\GH18478
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	17345 y1 w67c23; P{EPgy2}CG5835EY05431 17464 y1 w67c23; P{EPgy2}CG5835EY08453 16076 y1 w1118; PBac{5HPw+}CG5835A245
Harvard	- PBac{WH}CG5835f03135
Kyoto	105341 y* w*; P{GawB}CG5835NP7034 / TM6, P{UAS-lacZ.UW23-1}UW23-1
VDRC	v102220 P{KK111136}VIE-260B
Genomic Clones ( 2 )
	BACR17F04 BACR48G05 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 83 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH18370 RH70210
Other clones	FI04548
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LP21391 RE18761 RE33305 RE33786 RE37195 RE44909 RE73047
Other clones	214537.71 214537.72 EK042808 EP18754 FGM208H06 LD05245 RP003039607 RP003042452 RP003046778 RP003049838 RP003068016 RP003099983 RP003113876 RP003125881 RP003136350 RP003138747 RP003143593 RP003146377 RP003166989 RP003178774 RP003208052 RP003239997 RP003248725 RP003255317 RP003256349 RP003264584 RP003271836 RP003275873 RP003282944 RP003285549 RP003288996 RP003302627 RP003316517 RP003324193 RP003325461 RP003364984 RP003365182 RP003428591 RP003449713 RP003467176 RP003476459 RP003479614 RP003483442 RP003490205 RP003491966 RP003509459 RP003515862 RP003527123 RP003531498 RP003536102 RP003538258 RP003547600 RP003548096 RP003553022 RP003555190 RP003556621 RP003556741 RP003558435 RP003558489 RP003568997 RP003577678 RP003599276 RP003605429 RP003605489 RP003608692 RP003615456 RP003615515 RP003642696 RP003646935 RP003656271 RP003656300 RP003669443 RP003681245
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0038682 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42296
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_142528 RefSeq (Proteins) • NP_650785 DDBJ / EMBL / GenBank • AAF55638 AAF55638.2 AAL90433 AY089695 BI604745 CL525903 CZ485684 CZ485685 Entrez Gene - A searchable database of RefSeq genes. • 42296 UniProtKB/TrEMBL • Q8SXD8 Q9VDZ9
Other Crossreferences
Linkouts
	BioGRID - A database of protein and genetic interactions • 67294 DroID - A comprehensive database of gene and protein interactions. • FBgn0038682 DRSC - Results from RNAi screens. • FBgn0038682 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038682 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5835-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0038682 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42296 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42296 modMine - Data generated by the modENCODE project. • FBgn0038682
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG5835 (Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 15 )
Research paper	Bogwitz et al., 2005, Proc. Natl. Acad. Sci. U.S.A. 102(36): 12807--12812 Cyp12a4 confers lufenuron resistance in a natural population of Drosophila melanogaster. [FBrf0188252] Park et al., 2004, Genes Dev. 18(5): 584--594 Targeting of TAK1 by the NF-kappa B protein Relish regulates the JNK-mediated immune response in Drosophila. [FBrf0174647] Michaut et al., 2003, Proc. Natl. Acad. Sci. U.S.A. 100(7): 4024--4029 Analysis of the eye developmental pathway in Drosophila using DNA microarrays. [FBrf0159295]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Berkeley Drosophila Genome Project, 2006.4.26, BDGP TI submission. BDGP TI submission. [FBrf0188739] Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file) Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]