Gene Dmel\CG5191

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General Information

Symbol

Dmel\CG5191

Species

D. melanogaster

Name

Annotation symbol

CG5191

Feature type

protein_coding_gene

FlyBase ID

FBgn0038803

Gene Model Status

Current

Stock availability

11 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

92F1-92F2

Sequence location

3R:16,386,587..16,398,722 [+]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG5191 (FBgn0038803). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. The biological processes in which it is involved are not known. 10 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Amidase; Amidase signature domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 12-18 embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, adult hindgut, larval trachea, adult female reproductive system. Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval/adult midgut, larval hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1636244_s_at completely aligns to an exonic region common to each of the 5 FlyBase-annotated transcript isoforms of CG5191. Gene sequence location is 3R:16386587..16398722.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

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Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

92F1-92F2

Limits computationally determined from genome sequence between P{PZ}l(3)10585¹⁰⁵⁸⁵ and P{EP}Synd^EP409

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG5191 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.47

Low-frequency RNA-Seq exon junction(s) not annotated.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG5191-RA

FBtr0083904

NM_169904

2449

429

CG5191-RB

FBtr0083905

NM_142636

2630

552

CG5191-RC

FBtr0083908

NM_169902

2778

528

CG5191-RD

FBtr0083906

NM_169905

2506

429

CG5191-RE

FBtr0083907

NM_169903

2687

528

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG5191-PA

FBpp0083312

47.4

429

9.51

NP_732525

AAF55778

CG5191-PB

FBpp0083313

62.0

552

9.82

NP_650893

AAG22162

CG5191-PC

FBpp0083316

59.1

528

9.78

NP_732523

AAN14353

CG5191-PD

FBpp0083314

47.4

429

9.51

NP_732526

AAN14355

CG5191-PE

FBpp0083315

59.1

528

9.78

NP_732524

AAN14354

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Amidase (IPR000120)

Amidase signature domain (IPR023631)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, adult hindgut, larval trachea, adult female reproductive system. Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval/adult midgut, larval hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, adult male reproductive system, larval/adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		271.95
Larval Midgut		148.2
Larval Hindgut		282.1
Larval Malpighian Tubules		262.2
Larval Fat Body		98.9
Larval Salivary Gland		134.9
Larval Trachea		819.8
Larval Carcass		281.75
Adult Head		911.8
Adult Eye		1406.35
Adult Brain		635.5
Adult Thoracic-Abdominal Ganglion		765.7
Adult Crop		4215.6
Adult Midgut		221.4
Adult Hindgut		2352
Adult Malpighian Tubules		228.9
Adult Fat Body		320.8
Adult Salivary Gland		382.2
Adult Heart		208.75
Adult VirginFemale Spermatheca		568.1
Adult InseminatedFemale Spermatheca		516.9
Adult Ovary		567.5
Adult Testis		168.1
Adult Male Accessory Gland		204.1
Adult Carcass		443.6
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		271.95
Larval Midgut		148.2
Larval Hindgut		282.1
Larval Malpighian Tubules		262.2
Larval Fat Body		98.9
Larval Salivary Gland		134.9
Larval Trachea		(819.8)
Larval Carcass		281.75
Adult Head		(911.8)
Adult Eye		(1406.35)
Adult Brain		(635.5)
Adult Thoracic-Abdominal Ganglion		(765.7)
Adult Crop		(4215.6)
Adult Midgut		221.4
Adult Hindgut		(2352)
Adult Malpighian Tubules		228.9
Adult Fat Body		320.8
Adult Salivary Gland		382.2
Adult Heart		208.75
Adult VirginFemale Spermatheca		(568.1)
Adult InseminatedFemale Spermatheca		516.9
Adult Ovary		(567.5)
Adult Testis		168.1
Adult Male Accessory Gland		204.1
Adult Carcass		443.6
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		271.95
Larval Midgut		148.2
Larval Hindgut		282.1
Larval Malpighian Tubules		262.2
Larval Fat Body		98.9
Larval Salivary Gland		134.9
Larval Trachea		819.8
Larval Carcass		281.75
Adult Head		911.8
Adult Eye		(1406.35)
Adult Brain		635.5
Adult Thoracic-Abdominal Ganglion		765.7
Adult Crop		(4215.6)
Adult Midgut		221.4
Adult Hindgut		(2352)
Adult Malpighian Tubules		228.9
Adult Fat Body		320.8
Adult Salivary Gland		382.2
Adult Heart		208.75
Adult VirginFemale Spermatheca		568.1
Adult InseminatedFemale Spermatheca		516.9
Adult Ovary		567.5
Adult Testis		168.1
Adult Male Accessory Gland		204.1
Adult Carcass		443.6
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		271.95
Larval Midgut		148.2
Larval Hindgut		282.1
Larval Malpighian Tubules		262.2
Larval Fat Body		98.9
Larval Salivary Gland		134.9
Larval Trachea		819.8
Larval Carcass		281.75
Adult Head		911.8
Adult Eye		1406.35
Adult Brain		635.5
Adult Thoracic-Abdominal Ganglion		765.7
Adult Crop		4215.6
Adult Midgut		221.4
Adult Hindgut		2352
Adult Malpighian Tubules		228.9
Adult Fat Body		320.8
Adult Salivary Gland		382.2
Adult Heart		208.75
Adult VirginFemale Spermatheca		568.1
Adult InseminatedFemale Spermatheca		516.9
Adult Ovary		567.5
Adult Testis		168.1
Adult Male Accessory Gland		204.1
Adult Carcass		443.6
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		271.95
Larval Midgut		148.2
Larval Hindgut		282.1
Larval Malpighian Tubules		262.2
Larval Fat Body		98.9
Larval Salivary Gland		134.9
Larval Trachea		819.8
Larval Carcass		281.75
Adult Head		911.8
Adult Eye		1406.35
Adult Brain		635.5
Adult Thoracic-Abdominal Ganglion		765.7
Adult Crop		4215.6
Adult Midgut		221.4
Adult Hindgut		2352
Adult Malpighian Tubules		228.9
Adult Fat Body		320.8
Adult Salivary Gland		382.2
Adult Heart		208.75
Adult VirginFemale Spermatheca		568.1
Adult InseminatedFemale Spermatheca		516.9
Adult Ovary		567.5
Adult Testis		168.1
Adult Male Accessory Gland		204.1
Adult Carcass		443.6
Expression Level Scale		None Low Moderate High Very high

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		271.95
Larval Midgut		148.2
Larval Hindgut		282.1
Larval Malpighian Tubules		262.2
Larval Fat Body		98.9
Larval Salivary Gland		134.9
Larval Trachea		(819.8)
Larval Carcass		281.75
Adult Head		(911.8)
Adult Eye		(1406.35)
Adult Brain		635.5
Adult Thoracic-Abdominal Ganglion		765.7
Adult Crop		(4215.6)
Adult Midgut		221.4
Adult Hindgut		(2352)
Adult Malpighian Tubules		228.9
Adult Fat Body		320.8
Adult Salivary Gland		382.2
Adult Heart		208.75
Adult VirginFemale Spermatheca		568.1
Adult InseminatedFemale Spermatheca		516.9
Adult Ovary		567.5
Adult Testis		168.1
Adult Male Accessory Gland		204.1
Adult Carcass		443.6
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		271.95
Larval Midgut		148.2
Larval Hindgut		282.1
Larval Malpighian Tubules		262.2
Larval Fat Body		98.9
Larval Salivary Gland		134.9
Larval Trachea		819.8
Larval Carcass		281.75
Adult Head		911.8
Adult Eye		1406.35
Adult Brain		635.5
Adult Thoracic-Abdominal Ganglion		765.7
Adult Crop		(4215.6)
Adult Midgut		221.4
Adult Hindgut		(2352)
Adult Malpighian Tubules		228.9
Adult Fat Body		320.8
Adult Salivary Gland		382.2
Adult Heart		208.75
Adult VirginFemale Spermatheca		568.1
Adult InseminatedFemale Spermatheca		516.9
Adult Ovary		567.5
Adult Testis		168.1
Adult Male Accessory Gland		204.1
Adult Carcass		443.6
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		271.95
Larval Midgut		148.2
Larval Hindgut		282.1
Larval Malpighian Tubules		262.2
Larval Fat Body		98.9
Larval Salivary Gland		134.9
Larval Trachea		819.8
Larval Carcass		281.75
Adult Head		911.8
Adult Eye		1406.35
Adult Brain		635.5
Adult Thoracic-Abdominal Ganglion		765.7
Adult Crop		4215.6
Adult Midgut		221.4
Adult Hindgut		2352
Adult Malpighian Tubules		228.9
Adult Fat Body		320.8
Adult Salivary Gland		382.2
Adult Heart		208.75
Adult VirginFemale Spermatheca		568.1
Adult InseminatedFemale Spermatheca		516.9
Adult Ovary		567.5
Adult Testis		168.1
Adult Male Accessory Gland		204.1
Adult Carcass		443.6
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	911.8
NA	Eye	1406.35
NA	Brain	635.5
271.95	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	765.7
NA	Crop	4215.6
148.2	Midgut	221.4
282.1	Hindgut	2352
262.2	Malpighian Tubules	228.9
98.9	Fat Body	320.8
134.9	Salivary Gland	382.2
NA	Heart	208.75
819.8	Trachea	NA
NA	VirginFemale Spermatheca	568.1
NA	InseminatedFemale Spermatheca	516.9
NA	Ovary	567.5
NA	Testis	168.1
NA	Male Accessory Gland	204.1
281.75	Carcass	443.6

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		7
central nervous system, larvae L3		6
central nervous system, pupae P8		16
head, virgin 1-day female		18
head, virgin 4-day female		19
head, virgin 20-day female		17
head, mated 1-day female		17
head, mated 4-day female		12
head, mated 20-day female		13
head, mated 1-day male		24
head, mated 4-day male		17
head, mated 20-day male		19
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		12
digestive system, 4-day adult		9
digestive system, 20-day adult		8
fat body, larvae L3 wandering		1
fat body, white prepupae		6
fat body, pupae P8		22
carcass, larvae L3 wandering		12
carcass, 1-day adult		7
carcass, 4-day adult		7
carcass, 20-day adult		11
ovary, virgin 4-day female		13
ovary, mated 4-day female		11
testis, mated 4-day male		5
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		7
central nervous system, larvae L3		6
central nervous system, pupae P8		16
head, virgin 1-day female		18
head, virgin 4-day female		19
head, virgin 20-day female		17
head, mated 1-day female		17
head, mated 4-day female		12
head, mated 20-day female		13
head, mated 1-day male		24
head, mated 4-day male		17
head, mated 20-day male		19
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		12
digestive system, 4-day adult		9
digestive system, 20-day adult		8
fat body, larvae L3 wandering		1
fat body, white prepupae		6
fat body, pupae P8		22
carcass, larvae L3 wandering		12
carcass, 1-day adult		7
carcass, 4-day adult		7
carcass, 20-day adult		11
ovary, virgin 4-day female		13
ovary, mated 4-day female		11
testis, mated 4-day male		5
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		7
central nervous system, larvae L3		6
central nervous system, pupae P8		16
head, virgin 1-day female		18
head, virgin 4-day female		19
head, virgin 20-day female		17
head, mated 1-day female		17
head, mated 4-day female		12
head, mated 20-day female		13
head, mated 1-day male		24
head, mated 4-day male		17
head, mated 20-day male		19
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		12
digestive system, 4-day adult		9
digestive system, 20-day adult		8
fat body, larvae L3 wandering		1
fat body, white prepupae		6
fat body, pupae P8		22
carcass, larvae L3 wandering		12
carcass, 1-day adult		7
carcass, 4-day adult		7
carcass, 20-day adult		11
ovary, virgin 4-day female		13
ovary, mated 4-day female		11
testis, mated 4-day male		5
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		7
central nervous system, larvae L3		6
central nervous system, pupae P8		16
head, virgin 1-day female		18
head, virgin 4-day female		19
head, virgin 20-day female		17
head, mated 1-day female		17
head, mated 4-day female		12
head, mated 20-day female		13
head, mated 1-day male		24
head, mated 4-day male		17
head, mated 20-day male		19
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		12
digestive system, 4-day adult		9
digestive system, 20-day adult		8
fat body, larvae L3 wandering		1
fat body, white prepupae		6
fat body, pupae P8		22
carcass, larvae L3 wandering		12
carcass, 1-day adult		7
carcass, 4-day adult		7
carcass, 20-day adult		11
ovary, virgin 4-day female		13
ovary, mated 4-day female		11
testis, mated 4-day male		5
accessory gland, mated 4-day male		3
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		7
central nervous system, larvae L3		6
central nervous system, pupae P8		16
head, virgin 1-day female		18
head, virgin 4-day female		19
head, virgin 20-day female		17
head, mated 1-day female		17
head, mated 4-day female		12
head, mated 20-day female		13
head, mated 1-day male		24
head, mated 4-day male		17
head, mated 20-day male		19
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		12
digestive system, 4-day adult		9
digestive system, 20-day adult		8
fat body, larvae L3 wandering		1
fat body, white prepupae		6
fat body, pupae P8		22
carcass, larvae L3 wandering		12
carcass, 1-day adult		7
carcass, 4-day adult		7
carcass, 20-day adult		11
ovary, virgin 4-day female		13
ovary, mated 4-day female		11
testis, mated 4-day male		5
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		7
central nervous system, larvae L3		6
central nervous system, pupae P8		16
head, virgin 1-day female		18
head, virgin 4-day female		19
head, virgin 20-day female		17
head, mated 1-day female		17
head, mated 4-day female		12
head, mated 20-day female		13
head, mated 1-day male		24
head, mated 4-day male		17
head, mated 20-day male		19
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		12
digestive system, 4-day adult		9
digestive system, 20-day adult		8
fat body, larvae L3 wandering		1
fat body, white prepupae		6
fat body, pupae P8		22
carcass, larvae L3 wandering		12
carcass, 1-day adult		7
carcass, 4-day adult		7
carcass, 20-day adult		11
ovary, virgin 4-day female		13
ovary, mated 4-day female		11
testis, mated 4-day male		5
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		7
central nervous system, larvae L3		6
central nervous system, pupae P8		16
head, virgin 1-day female		18
head, virgin 4-day female		19
head, virgin 20-day female		17
head, mated 1-day female		17
head, mated 4-day female		12
head, mated 20-day female		13
head, mated 1-day male		24
head, mated 4-day male		17
head, mated 20-day male		19
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		12
digestive system, 4-day adult		9
digestive system, 20-day adult		8
fat body, larvae L3 wandering		1
fat body, white prepupae		6
fat body, pupae P8		22
carcass, larvae L3 wandering		12
carcass, 1-day adult		7
carcass, 4-day adult		7
carcass, 20-day adult		11
ovary, virgin 4-day female		13
ovary, mated 4-day female		11
testis, mated 4-day male		5
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		7
central nervous system, larvae L3		6
central nervous system, pupae P8		16
head, virgin 1-day female		18
head, virgin 4-day female		19
head, virgin 20-day female		17
head, mated 1-day female		17
head, mated 4-day female		12
head, mated 20-day female		13
head, mated 1-day male		24
head, mated 4-day male		17
head, mated 20-day male		19
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		12
digestive system, 4-day adult		9
digestive system, 20-day adult		8
fat body, larvae L3 wandering		1
fat body, white prepupae		6
fat body, pupae P8		22
carcass, larvae L3 wandering		12
carcass, 1-day adult		7
carcass, 4-day adult		7
carcass, 20-day adult		11
ovary, virgin 4-day female		13
ovary, mated 4-day female		11
testis, mated 4-day male		5
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 12-18 embryonic stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		20
embryo 02-04hr		24
embryo 04-06hr		29
embryo 06-08hr		14
embryo 08-10hr		11
embryo 10-12hr		18
embryo 12-14hr		23
embryo 14-16hr		57
embryo 16-18hr		59
embryo 18-20hr		41
embryo 20-22hr		19
embryo 22-24hr		20
larva L1		8
larva L2		4
larva L3 12hr old		6
larva L3 puffstage 1-2		4
larva L3 puffstage 3-6		7
larva L3 puffstage 7-9		8
white prepupae new		6
white prepupae 12hr		42
white prepupae 24hr		21
pupae 2d postWPP		21
pupae 3d postWPP		41
pupae 4d postWPP		12
adult male 01day		14
adult male 05day		16
adult male 30day		16
adult female 01day		14
adult female 05day		15
adult female 30day		17
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		20
embryo 02-04hr		24
embryo 04-06hr		(29)
embryo 06-08hr		14
embryo 08-10hr		11
embryo 10-12hr		18
embryo 12-14hr		23
embryo 14-16hr		(57)
embryo 16-18hr		(59)
embryo 18-20hr		(41)
embryo 20-22hr		19
embryo 22-24hr		20
larva L1		8
larva L2		4
larva L3 12hr old		6
larva L3 puffstage 1-2		4
larva L3 puffstage 3-6		7
larva L3 puffstage 7-9		8
white prepupae new		6
white prepupae 12hr		(42)
white prepupae 24hr		21
pupae 2d postWPP		21
pupae 3d postWPP		(41)
pupae 4d postWPP		12
adult male 01day		14
adult male 05day		16
adult male 30day		16
adult female 01day		14
adult female 05day		15
adult female 30day		17
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		20
embryo 02-04hr		24
embryo 04-06hr		29
embryo 06-08hr		14
embryo 08-10hr		11
embryo 10-12hr		18
embryo 12-14hr		23
embryo 14-16hr		57
embryo 16-18hr		59
embryo 18-20hr		41
embryo 20-22hr		19
embryo 22-24hr		20
larva L1		8
larva L2		4
larva L3 12hr old		6
larva L3 puffstage 1-2		4
larva L3 puffstage 3-6		7
larva L3 puffstage 7-9		8
white prepupae new		6
white prepupae 12hr		42
white prepupae 24hr		21
pupae 2d postWPP		21
pupae 3d postWPP		41
pupae 4d postWPP		12
adult male 01day		14
adult male 05day		16
adult male 30day		16
adult female 01day		14
adult female 05day		15
adult female 30day		17
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		20
embryo 02-04hr		24
embryo 04-06hr		29
embryo 06-08hr		14
embryo 08-10hr		11
embryo 10-12hr		18
embryo 12-14hr		23
embryo 14-16hr		57
embryo 16-18hr		59
embryo 18-20hr		41
embryo 20-22hr		19
embryo 22-24hr		20
larva L1		8
larva L2		4
larva L3 12hr old		6
larva L3 puffstage 1-2		4
larva L3 puffstage 3-6		7
larva L3 puffstage 7-9		8
white prepupae new		6
white prepupae 12hr		42
white prepupae 24hr		21
pupae 2d postWPP		21
pupae 3d postWPP		41
pupae 4d postWPP		12
adult male 01day		14
adult male 05day		16
adult male 30day		16
adult female 01day		14
adult female 05day		15
adult female 30day		17
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		20
embryo 02-04hr		24
embryo 04-06hr		29
embryo 06-08hr		14
embryo 08-10hr		11
embryo 10-12hr		18
embryo 12-14hr		23
embryo 14-16hr		57
embryo 16-18hr		59
embryo 18-20hr		41
embryo 20-22hr		19
embryo 22-24hr		20
larva L1		8
larva L2		4
larva L3 12hr old		6
larva L3 puffstage 1-2		4
larva L3 puffstage 3-6		7
larva L3 puffstage 7-9		8
white prepupae new		6
white prepupae 12hr		42
white prepupae 24hr		21
pupae 2d postWPP		21
pupae 3d postWPP		41
pupae 4d postWPP		12
adult male 01day		14
adult male 05day		16
adult male 30day		16
adult female 01day		14
adult female 05day		15
adult female 30day		17
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		20
embryo 02-04hr		24
embryo 04-06hr		29
embryo 06-08hr		14
embryo 08-10hr		11
embryo 10-12hr		18
embryo 12-14hr		23
embryo 14-16hr		(57)
embryo 16-18hr		(59)
embryo 18-20hr		(41)
embryo 20-22hr		19
embryo 22-24hr		20
larva L1		8
larva L2		4
larva L3 12hr old		6
larva L3 puffstage 1-2		4
larva L3 puffstage 3-6		7
larva L3 puffstage 7-9		8
white prepupae new		6
white prepupae 12hr		(42)
white prepupae 24hr		21
pupae 2d postWPP		21
pupae 3d postWPP		(41)
pupae 4d postWPP		12
adult male 01day		14
adult male 05day		16
adult male 30day		16
adult female 01day		14
adult female 05day		15
adult female 30day		17
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		20
embryo 02-04hr		24
embryo 04-06hr		29
embryo 06-08hr		14
embryo 08-10hr		11
embryo 10-12hr		18
embryo 12-14hr		23
embryo 14-16hr		57
embryo 16-18hr		59
embryo 18-20hr		41
embryo 20-22hr		19
embryo 22-24hr		20
larva L1		8
larva L2		4
larva L3 12hr old		6
larva L3 puffstage 1-2		4
larva L3 puffstage 3-6		7
larva L3 puffstage 7-9		8
white prepupae new		6
white prepupae 12hr		42
white prepupae 24hr		21
pupae 2d postWPP		21
pupae 3d postWPP		41
pupae 4d postWPP		12
adult male 01day		14
adult male 05day		16
adult male 30day		16
adult female 01day		14
adult female 05day		15
adult female 30day		17
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		20
embryo 02-04hr		24
embryo 04-06hr		29
embryo 06-08hr		14
embryo 08-10hr		11
embryo 10-12hr		18
embryo 12-14hr		23
embryo 14-16hr		57
embryo 16-18hr		59
embryo 18-20hr		41
embryo 20-22hr		19
embryo 22-24hr		20
larva L1		8
larva L2		4
larva L3 12hr old		6
larva L3 puffstage 1-2		4
larva L3 puffstage 3-6		7
larva L3 puffstage 7-9		8
white prepupae new		6
white prepupae 12hr		42
white prepupae 24hr		21
pupae 2d postWPP		21
pupae 3d postWPP		41
pupae 4d postWPP		12
adult male 01day		14
adult male 05day		16
adult male 30day		16
adult female 01day		14
adult female 05day		15
adult female 30day		17
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		10
Schneider line 2 Sg4		6
embryonic 1182-4H		2
embryonic GM2		0
embryonic Kc167		4
embryonic S1		8
embryonic S3		16
leg disc CME L1		7
wing disc CME-W2		3
wing disc ML-DmD8		8
wing disc ML-DmD9		6
wing disc ML-DmD16-c3		4
wing disc ML-DmD21		2
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		4
eye-antennal disc ML-DmD11		1
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		27
CNS ML-DmBG1-c1		1
CNS ML-DmBG2-c2		1
tumorous blood cells mbn2		5
ovary fGS/OSS		29
ovary OSC		35
ovary OSS		27
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		10
Schneider line 2 Sg4		6
embryonic 1182-4H		2
embryonic GM2		0
embryonic Kc167		4
embryonic S1		8
embryonic S3		16
leg disc CME L1		7
wing disc CME-W2		3
wing disc ML-DmD8		8
wing disc ML-DmD9		6
wing disc ML-DmD16-c3		4
wing disc ML-DmD21		2
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		4
eye-antennal disc ML-DmD11		1
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		(27)
CNS ML-DmBG1-c1		1
CNS ML-DmBG2-c2		1
tumorous blood cells mbn2		5
ovary fGS/OSS		(29)
ovary OSC		(35)
ovary OSS		(27)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		10
Schneider line 2 Sg4		6
embryonic 1182-4H		2
embryonic GM2		0
embryonic Kc167		4
embryonic S1		8
embryonic S3		16
leg disc CME L1		7
wing disc CME-W2		3
wing disc ML-DmD8		8
wing disc ML-DmD9		6
wing disc ML-DmD16-c3		4
wing disc ML-DmD21		2
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		4
eye-antennal disc ML-DmD11		1
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		27
CNS ML-DmBG1-c1		1
CNS ML-DmBG2-c2		1
tumorous blood cells mbn2		5
ovary fGS/OSS		29
ovary OSC		35
ovary OSS		27
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		10
Schneider line 2 Sg4		6
embryonic 1182-4H		2
embryonic GM2		0
embryonic Kc167		4
embryonic S1		8
embryonic S3		16
leg disc CME L1		7
wing disc CME-W2		3
wing disc ML-DmD8		8
wing disc ML-DmD9		6
wing disc ML-DmD16-c3		4
wing disc ML-DmD21		2
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		4
eye-antennal disc ML-DmD11		1
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		27
CNS ML-DmBG1-c1		1
CNS ML-DmBG2-c2		1
tumorous blood cells mbn2		5
ovary fGS/OSS		29
ovary OSC		35
ovary OSS		27
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		10
Schneider line 2 Sg4		6
embryonic 1182-4H		2
embryonic GM2		0
embryonic Kc167		4
embryonic S1		8
embryonic S3		16
leg disc CME L1		7
wing disc CME-W2		3
wing disc ML-DmD8		8
wing disc ML-DmD9		6
wing disc ML-DmD16-c3		4
wing disc ML-DmD21		2
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		4
eye-antennal disc ML-DmD11		1
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		27
CNS ML-DmBG1-c1		1
CNS ML-DmBG2-c2		1
tumorous blood cells mbn2		5
ovary fGS/OSS		29
ovary OSC		35
ovary OSS		27
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		10
Schneider line 2 Sg4		6
embryonic 1182-4H		2
embryonic GM2		0
embryonic Kc167		4
embryonic S1		8
embryonic S3		16
leg disc CME L1		7
wing disc CME-W2		3
wing disc ML-DmD8		8
wing disc ML-DmD9		6
wing disc ML-DmD16-c3		4
wing disc ML-DmD21		2
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		4
eye-antennal disc ML-DmD11		1
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		27
CNS ML-DmBG1-c1		1
CNS ML-DmBG2-c2		1
tumorous blood cells mbn2		5
ovary fGS/OSS		29
ovary OSC		(35)
ovary OSS		27
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		10
Schneider line 2 Sg4		6
embryonic 1182-4H		2
embryonic GM2		0
embryonic Kc167		4
embryonic S1		8
embryonic S3		16
leg disc CME L1		7
wing disc CME-W2		3
wing disc ML-DmD8		8
wing disc ML-DmD9		6
wing disc ML-DmD16-c3		4
wing disc ML-DmD21		2
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		4
eye-antennal disc ML-DmD11		1
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		27
CNS ML-DmBG1-c1		1
CNS ML-DmBG2-c2		1
tumorous blood cells mbn2		5
ovary fGS/OSS		29
ovary OSC		35
ovary OSS		27
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		10
Schneider line 2 Sg4		6
embryonic 1182-4H		2
embryonic GM2		0
embryonic Kc167		4
embryonic S1		8
embryonic S3		16
leg disc CME L1		7
wing disc CME-W2		3
wing disc ML-DmD8		8
wing disc ML-DmD9		6
wing disc ML-DmD16-c3		4
wing disc ML-DmD21		2
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		4
eye-antennal disc ML-DmD11		1
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		27
CNS ML-DmBG1-c1		1
CNS ML-DmBG2-c2		1
tumorous blood cells mbn2		5
ovary fGS/OSS		29
ovary OSC		35
ovary OSS		27
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		8
cold shock, 4-day adult		4
heat shock, 4-day adult		6
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		4
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		15
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		6
Zinc 5 mM 12 hrs, larvae L3		3
Zinc 4.5 mM 48 hrs, 4-day adult		8
Ethanol 2.5% 3 hrs, larvae L3		15
Ethanol 5% 3 hrs, larvae L3		8
Ethanol 10% 3 hrs, larvae L3		5
Caffeine 1.5 mg/ml 4 hrs, larvae L3		9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		13
Caffeine 25 mg/ml 48 hrs, 4-day adult		6
Paraquat 5 mM 48 hrs, 4-day adult		12
Paraquat 10 mM 48 hrs, 4-day adult		14
Rotenone 2 μg 12 hrs, larvae L3		3
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		8
cold shock, 4-day adult		4
heat shock, 4-day adult		6
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		4
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		15
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		6
Zinc 5 mM 12 hrs, larvae L3		3
Zinc 4.5 mM 48 hrs, 4-day adult		8
Ethanol 2.5% 3 hrs, larvae L3		15
Ethanol 5% 3 hrs, larvae L3		8
Ethanol 10% 3 hrs, larvae L3		5
Caffeine 1.5 mg/ml 4 hrs, larvae L3		9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		13
Caffeine 25 mg/ml 48 hrs, 4-day adult		6
Paraquat 5 mM 48 hrs, 4-day adult		12
Paraquat 10 mM 48 hrs, 4-day adult		14
Rotenone 2 μg 12 hrs, larvae L3		3
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		8
cold shock, 4-day adult		4
heat shock, 4-day adult		6
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		4
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		15
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		6
Zinc 5 mM 12 hrs, larvae L3		3
Zinc 4.5 mM 48 hrs, 4-day adult		8
Ethanol 2.5% 3 hrs, larvae L3		15
Ethanol 5% 3 hrs, larvae L3		8
Ethanol 10% 3 hrs, larvae L3		5
Caffeine 1.5 mg/ml 4 hrs, larvae L3		9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		13
Caffeine 25 mg/ml 48 hrs, 4-day adult		6
Paraquat 5 mM 48 hrs, 4-day adult		12
Paraquat 10 mM 48 hrs, 4-day adult		14
Rotenone 2 μg 12 hrs, larvae L3		3
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		8
cold shock, 4-day adult		4
heat shock, 4-day adult		6
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		4
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		15
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		6
Zinc 5 mM 12 hrs, larvae L3		3
Zinc 4.5 mM 48 hrs, 4-day adult		8
Ethanol 2.5% 3 hrs, larvae L3		15
Ethanol 5% 3 hrs, larvae L3		8
Ethanol 10% 3 hrs, larvae L3		5
Caffeine 1.5 mg/ml 4 hrs, larvae L3		9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		13
Caffeine 25 mg/ml 48 hrs, 4-day adult		6
Paraquat 5 mM 48 hrs, 4-day adult		12
Paraquat 10 mM 48 hrs, 4-day adult		14
Rotenone 2 μg 12 hrs, larvae L3		3
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		8
cold shock, 4-day adult		4
heat shock, 4-day adult		6
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		4
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		15
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		6
Zinc 5 mM 12 hrs, larvae L3		3
Zinc 4.5 mM 48 hrs, 4-day adult		8
Ethanol 2.5% 3 hrs, larvae L3		15
Ethanol 5% 3 hrs, larvae L3		8
Ethanol 10% 3 hrs, larvae L3		5
Caffeine 1.5 mg/ml 4 hrs, larvae L3		9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		13
Caffeine 25 mg/ml 48 hrs, 4-day adult		6
Paraquat 5 mM 48 hrs, 4-day adult		12
Paraquat 10 mM 48 hrs, 4-day adult		14
Rotenone 2 μg 12 hrs, larvae L3		3
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		8
cold shock, 4-day adult		4
heat shock, 4-day adult		6
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		4
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		15
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		6
Zinc 5 mM 12 hrs, larvae L3		3
Zinc 4.5 mM 48 hrs, 4-day adult		8
Ethanol 2.5% 3 hrs, larvae L3		15
Ethanol 5% 3 hrs, larvae L3		8
Ethanol 10% 3 hrs, larvae L3		5
Caffeine 1.5 mg/ml 4 hrs, larvae L3		9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		13
Caffeine 25 mg/ml 48 hrs, 4-day adult		6
Paraquat 5 mM 48 hrs, 4-day adult		12
Paraquat 10 mM 48 hrs, 4-day adult		14
Rotenone 2 μg 12 hrs, larvae L3		3
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		8
cold shock, 4-day adult		4
heat shock, 4-day adult		6
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		4
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		15
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		6
Zinc 5 mM 12 hrs, larvae L3		3
Zinc 4.5 mM 48 hrs, 4-day adult		8
Ethanol 2.5% 3 hrs, larvae L3		15
Ethanol 5% 3 hrs, larvae L3		8
Ethanol 10% 3 hrs, larvae L3		5
Caffeine 1.5 mg/ml 4 hrs, larvae L3		9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		13
Caffeine 25 mg/ml 48 hrs, 4-day adult		6
Paraquat 5 mM 48 hrs, 4-day adult		12
Paraquat 10 mM 48 hrs, 4-day adult		14
Rotenone 2 μg 12 hrs, larvae L3		3
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		8
cold shock, 4-day adult		4
heat shock, 4-day adult		6
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		4
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		15
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		6
Zinc 5 mM 12 hrs, larvae L3		3
Zinc 4.5 mM 48 hrs, 4-day adult		8
Ethanol 2.5% 3 hrs, larvae L3		15
Ethanol 5% 3 hrs, larvae L3		8
Ethanol 10% 3 hrs, larvae L3		5
Caffeine 1.5 mg/ml 4 hrs, larvae L3		9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		13
Caffeine 25 mg/ml 48 hrs, 4-day adult		6
Paraquat 5 mM 48 hrs, 4-day adult		12
Paraquat 10 mM 48 hrs, 4-day adult		14
Rotenone 2 μg 12 hrs, larvae L3		3
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0038803

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG5191-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable

viable, with Scer\GAL4^pnr-MD237

CG5191^GD5170

Sterility

Allele

fertile

Phenotype manifest in

Allele

Classical Alleles ( 7 )

For All Classical Alleles Show

Allele of CG5191	Mutagen	Stocks	Known lesion
CG5191^c00205	piggyBac transposase	2	--
CG5191^e01351	piggyBac transposase	2	--
CG5191^e01473	piggyBac transposase	1	--
CG5191^f05441	piggyBac transposase	1	--
CG5191^MB00040		1	--
CG5191^MI01991		1	--
CG5191^MI07551		1	--

Alleles Carried on Transgenic Constructs ( 3 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG5191	Mutagen	Stocks	Known lesion
CG5191^GD5170	in vitro construct - RNAi in vitro construct - regulatory fusion	2	Yes
CG5191^KK109828	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes
CG5191^NIG.5191R	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD5170}

P{KK109828}

P{NIG.5191R}

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

Mi{MIC}CG5191^MI01991

Mi{MIC}CG5191^MI07551

PBac{PB}CG5191^c00205

PBac{RB}CG5191^e01351

PBac{RB}CG5191^e01473

PBac{WH}CG5191^f05441

insertion of enhancer trap binary system

Mi{ET1}CG5191^MB00040

Gene Ontology: Function, Process & Cellular Component ( 1 unique term )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 1 term )

Molecular Function

CV term

Evidence

References

glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity

inferred from sequence or structural similarity with EMBL:AE000968

(FlyBase, 1992-)

Biological Process ( 0 terms)

Cellular Component ( 0 terms)

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG5191 allele

Gene

References

External Data

Linkouts

BioGRID - A database of protein and genetic interactions

•

67409

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0038803

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

42431

Orthologs

OrthoDB Orthologs (24) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG612MR3

Dipteran inclusive ortholog search

EOG6XH07D

Insect inclusive ortholog search

EOG68W9XD

Arthropod inclusive ortholog search

No orthologs identified

Metazoa inclusive ortholog search

No orthologs identified

Orthologs in Drosophila Species (EOG612MR3)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA18724

Drosophila persimilis

Dper\GL13563

Drosophila willistoni

Dwil\GK22453

Drosophila virilis

Dvir\GJ23043

Drosophila mojavensis

Dmoj\GI22238

Drosophila grimshawi

Dgri\GH14157

Orthologs in non-Drosophila Dipterans (EOG6XH07D)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL006181

Anopheles gambiae

Malaria mosquito

Agam\AGAP001699

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ001362

Orthologs in non-Dipteran Insects (EOG68W9XD)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH11280

Atta cephalotes

Leafcutter ant

Acep\ACEP14275

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO22915

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL16686

Linepithema humile

Argentine ant

Lhum\LH16327

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB17561

Solenopsis invicta

Red fire ant

Sinv\SINV10948

Bombyx mori

Silkmoth

Bmor\BGIBMGA012491

Tribolium castaneum

Red flour beetle

Tcas\TC000675

Orthologs in non-Insect Arthropods (None identified)

No non-Insect Arthropod orthologies identified

Orthologs in non-Arthropod Metazoa (None identified)

No non-Arthropod Metazoa orthologies identified

Human Orthologs (0)

Gene

OMIM

HGNC

AAA Orthologs (11) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA18724

Drosophila persimilis

Dper\GL13563

Drosophila willistoni

Dwil\GK22453

Drosophila virilis

Dvir\GJ23043

Drosophila mojavensis

Dmoj\GI22238

Drosophila grimshawi

Dgri\GH14157

Stocks & Reagents

Stocks Listed in FlyBase ( 11 )

Bloomington

10025

w¹¹¹⁸; PBac{PB}CG5191^c00205

17947

w¹¹¹⁸; PBac{RB}CG5191^e01351

43726

y¹ w^*; Mi{MIC}CG5191^MI07551

22681

y¹ w^67c23; Mi{ET1}CG5191^MB00040

41025

y¹ w^*; Mi{MIC}CG5191^MI01991/TM3, Sb¹ Ser¹

Harvard

PBac{PB}CG5191^c00205

PBac{RB}CG5191^e01351

PBac{RB}CG5191^e01473

PBac{WH}CG5191^f05441

VDRC

v41188

w¹¹¹⁸ P{GD5170}v41188

v41187

w¹¹¹⁸; P{GD5170}v41187/TM3

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 87 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones