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Gene Dmel\CG3822

General Information
Symbol	Dmel\CG3822	Species	D. melanogaster
Name		Annotation symbol	CG3822
Feature type	protein_coding_gene	FlyBase ID	FBgn0038837
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	93A2-93A2	Sequence location	3R:16,685,909..16,691,953 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG3822 (FBgn0038837). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: kainate selective glutamate receptor activity. Based on sequence similarity, it is predicted to be involved in the biological process: regulation of synaptic activity. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Extracellular ligand-binding receptor; Glutamate receptor, L-glutamate/glycine-binding; Ionotropic glutamate receptor; NMDA receptor. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 12-18 embryonic stages, at stages throughout the pupal period. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system. Comments on Affy2 ProbeSet: ProbeSet 1634462_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG3822. Gene sequence location is 3R:16685909..16691953.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02	Controlled Vocabulary Terms regulation of synaptic activity plasma membrane
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 93A2-93A2   Limits computationally determined from genome sequence between P{EP}SyndEP409 and P{lacW}l(3)j5C7j5C7
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG3822 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.47
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG3822-RA FBtr0083987  NM_142668   3607   853
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG3822-PA   FBpp0083391   95.9   853   7.73     NP_650925   AAF55818
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Ionotropic glutamate receptor (IPR001320) NMDA receptor (IPR001508) Extracellular ligand-binding receptor (IPR001828) Glutamate receptor, L-glutamate/glycine-binding (IPR019594)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF55818   AY119103 AAM50963   BI166565   CO178875   CO273470   CO277449   CO277902   CO298033   CO308718   CO309566   CO325299   CO325323   CZ486077   CZ486078   EC066290   EC071982   EC072709   EC074873   EC199693   EC202962   EC223861   EC224966   EC241709   EC243676   EC244379   GH780970   GH781950   GH783414   GH789628   GH790171   GH794712   GH799353   GH802972   GH811189   GH812029   GH818724   GH828798   GH829537   GH832624   GH841479   GH841698   GH854728   GH855222   GH862173   GH864972   GH865163   GH867249   GH872135   GH882268   GH885766   GH890335   GH890680   GH891161   GH895448   GH898257   GH898758   GH902217   GH909600   GH909765   GH919841   GH922965   GH930722   GH932576   GH932849   GH933094   GH934433   GH935742   GH939174   GH940679
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VDH5 Q8MS48
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    120.8 Larval Midgut    4.8 Larval Hindgut    2.2 Larval Malpighian Tubules    1.6 Larval Fat Body    2.5 Larval Salivary Gland    2.5 Larval Trachea    2.425 Larval Carcass    2.1 Adult Head    24.2 Adult Eye    16.15 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    62.3 Adult Crop    3.8 Adult Midgut    5.1 Adult Hindgut    2.1 Adult Malpighian Tubules    3 Adult Fat Body    9 Adult Salivary Gland    2.3 Adult Heart    3.025 Adult VirginFemale Spermatheca    4.1 Adult InseminatedFemale Spermatheca    3.5 Adult Ovary    2 Adult Testis    2.9 Adult Male Accessory Gland    2.5 Adult Carcass    2.9 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    120.8 Larval Midgut    4.8 Larval Hindgut    2.2 Larval Malpighian Tubules    1.6 Larval Fat Body    2.5 Larval Salivary Gland    2.5 Larval Trachea    2.425 Larval Carcass    2.1 Adult Head    24.2 Adult Eye    16.15 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    62.3 Adult Crop    3.8 Adult Midgut    5.1 Adult Hindgut    2.1 Adult Malpighian Tubules    3 Adult Fat Body    9 Adult Salivary Gland    2.3 Adult Heart    3.025 Adult VirginFemale Spermatheca    4.1 Adult InseminatedFemale Spermatheca    3.5 Adult Ovary    2 Adult Testis    2.9 Adult Male Accessory Gland    2.5 Adult Carcass    2.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    120.8 Larval Midgut    4.8 Larval Hindgut    2.2 Larval Malpighian Tubules    1.6 Larval Fat Body    2.5 Larval Salivary Gland    2.5 Larval Trachea    2.425 Larval Carcass    2.1 Adult Head    24.2 Adult Eye    16.15 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    62.3 Adult Crop    3.8 Adult Midgut    5.1 Adult Hindgut    2.1 Adult Malpighian Tubules    3 Adult Fat Body    9 Adult Salivary Gland    2.3 Adult Heart    3.025 Adult VirginFemale Spermatheca    4.1 Adult InseminatedFemale Spermatheca    3.5 Adult Ovary    2 Adult Testis    2.9 Adult Male Accessory Gland    2.5 Adult Carcass    2.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    120.8 Larval Midgut    4.8 Larval Hindgut    2.2 Larval Malpighian Tubules    1.6 Larval Fat Body    2.5 Larval Salivary Gland    2.5 Larval Trachea    2.425 Larval Carcass    2.1 Adult Head    24.2 Adult Eye    16.15 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    62.3 Adult Crop    3.8 Adult Midgut    5.1 Adult Hindgut    2.1 Adult Malpighian Tubules    3 Adult Fat Body    9 Adult Salivary Gland    2.3 Adult Heart    3.025 Adult VirginFemale Spermatheca    4.1 Adult InseminatedFemale Spermatheca    3.5 Adult Ovary    2 Adult Testis    2.9 Adult Male Accessory Gland    2.5 Adult Carcass    2.9 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    120.8 Larval Midgut    4.8 Larval Hindgut    2.2 Larval Malpighian Tubules    1.6 Larval Fat Body    2.5 Larval Salivary Gland    2.5 Larval Trachea    2.425 Larval Carcass    2.1 Adult Head    24.2 Adult Eye    16.15 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    62.3 Adult Crop    3.8 Adult Midgut    5.1 Adult Hindgut    2.1 Adult Malpighian Tubules    3 Adult Fat Body    9 Adult Salivary Gland    2.3 Adult Heart    3.025 Adult VirginFemale Spermatheca    4.1 Adult InseminatedFemale Spermatheca    3.5 Adult Ovary    2 Adult Testis    2.9 Adult Male Accessory Gland    2.5 Adult Carcass    2.9 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    120.8 Larval Midgut    4.8 Larval Hindgut    2.2 Larval Malpighian Tubules    1.6 Larval Fat Body    2.5 Larval Salivary Gland    2.5 Larval Trachea    2.425 Larval Carcass    2.1 Adult Head    24.2 Adult Eye    16.15 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    62.3 Adult Crop    3.8 Adult Midgut    5.1 Adult Hindgut    2.1 Adult Malpighian Tubules    3 Adult Fat Body    9 Adult Salivary Gland    2.3 Adult Heart    3.025 Adult VirginFemale Spermatheca    4.1 Adult InseminatedFemale Spermatheca    3.5 Adult Ovary    2 Adult Testis    2.9 Adult Male Accessory Gland    2.5 Adult Carcass    2.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    120.8 Larval Midgut    4.8 Larval Hindgut    2.2 Larval Malpighian Tubules    1.6 Larval Fat Body    2.5 Larval Salivary Gland    2.5 Larval Trachea    2.425 Larval Carcass    2.1 Adult Head    24.2 Adult Eye    16.15 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    62.3 Adult Crop    3.8 Adult Midgut    5.1 Adult Hindgut    2.1 Adult Malpighian Tubules    3 Adult Fat Body    9 Adult Salivary Gland    2.3 Adult Heart    3.025 Adult VirginFemale Spermatheca    4.1 Adult InseminatedFemale Spermatheca    3.5 Adult Ovary    2 Adult Testis    2.9 Adult Male Accessory Gland    2.5 Adult Carcass    2.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    120.8 Larval Midgut    4.8 Larval Hindgut    2.2 Larval Malpighian Tubules    1.6 Larval Fat Body    2.5 Larval Salivary Gland    2.5 Larval Trachea    2.425 Larval Carcass    2.1 Adult Head    24.2 Adult Eye    16.15 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    62.3 Adult Crop    3.8 Adult Midgut    5.1 Adult Hindgut    2.1 Adult Malpighian Tubules    3 Adult Fat Body    9 Adult Salivary Gland    2.3 Adult Heart    3.025 Adult VirginFemale Spermatheca    4.1 Adult InseminatedFemale Spermatheca    3.5 Adult Ovary    2 Adult Testis    2.9 Adult Male Accessory Gland    2.5 Adult Carcass    2.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    24.2   NA  Eye    16.15   NA  Brain    177.5   120.8  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    62.3   NA  Crop    3.8   4.8  Midgut    5.1   2.2  Hindgut    2.1   1.6  Malpighian Tubules    3   2.5  Fat Body    9   2.5  Salivary Gland    2.3   NA  Heart    3.025   2.425  Trachea    NA   NA  VirginFemale Spermatheca    4.1   NA  InseminatedFemale Spermatheca    3.5   NA  Ovary    2   NA  Testis    2.9   NA  Male Accessory Gland    2.5   2.1  Carcass    2.9 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    29 central nervous system, pupae P8    103 head, virgin 1-day female    13 head, virgin 4-day female    10 head, virgin 20-day female    8 head, mated 1-day female    8 head, mated 4-day female    8 head, mated 20-day female    5 head, mated 1-day male    13 head, mated 4-day male    12 head, mated 20-day male    12 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    22 carcass, larvae L3 wandering    4 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3  (29) central nervous system, pupae P8  (103) head, virgin 1-day female    13 head, virgin 4-day female    10 head, virgin 20-day female    8 head, mated 1-day female    8 head, mated 4-day female    8 head, mated 20-day female    5 head, mated 1-day male    13 head, mated 4-day male    12 head, mated 20-day male    12 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    22 carcass, larvae L3 wandering    4 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    29 central nervous system, pupae P8  103 head, virgin 1-day female    13 head, virgin 4-day female    10 head, virgin 20-day female    8 head, mated 1-day female    8 head, mated 4-day female    8 head, mated 20-day female    5 head, mated 1-day male    13 head, mated 4-day male    12 head, mated 20-day male    12 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    22 carcass, larvae L3 wandering    4 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    29 central nervous system, pupae P8    103 head, virgin 1-day female    13 head, virgin 4-day female    10 head, virgin 20-day female    8 head, mated 1-day female    8 head, mated 4-day female    8 head, mated 20-day female    5 head, mated 1-day male    13 head, mated 4-day male    12 head, mated 20-day male    12 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    22 carcass, larvae L3 wandering    4 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    29 central nervous system, pupae P8    103 head, virgin 1-day female    13 head, virgin 4-day female    10 head, virgin 20-day female    8 head, mated 1-day female    8 head, mated 4-day female    8 head, mated 20-day female    5 head, mated 1-day male    13 head, mated 4-day male    12 head, mated 20-day male    12 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    22 carcass, larvae L3 wandering    4 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3  29 central nervous system, pupae P8  (103) head, virgin 1-day female    13 head, virgin 4-day female    10 head, virgin 20-day female    8 head, mated 1-day female    8 head, mated 4-day female    8 head, mated 20-day female    5 head, mated 1-day male    13 head, mated 4-day male    12 head, mated 20-day male    12 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    22 carcass, larvae L3 wandering    4 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    29 central nervous system, pupae P8  103 head, virgin 1-day female    13 head, virgin 4-day female    10 head, virgin 20-day female    8 head, mated 1-day female    8 head, mated 4-day female    8 head, mated 20-day female    5 head, mated 1-day male    13 head, mated 4-day male    12 head, mated 20-day male    12 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    22 carcass, larvae L3 wandering    4 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    29 central nervous system, pupae P8    103 head, virgin 1-day female    13 head, virgin 4-day female    10 head, virgin 20-day female    8 head, mated 1-day female    8 head, mated 4-day female    8 head, mated 20-day female    5 head, mated 1-day male    13 head, mated 4-day male    12 head, mated 20-day male    12 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    22 carcass, larvae L3 wandering    4 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 12-18 embryonic stages, at stages throughout the pupal period. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    7 embryo 12-14hr    12 embryo 14-16hr    21 embryo 16-18hr    19 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    10 larva L2    4 larva L3 12hr old    1 larva L3 puffstage 1-2    1 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    5 white prepupae 12hr    14 white prepupae 24hr    24 pupae 2d postWPP    24 pupae 3d postWPP    12 pupae 4d postWPP    3 adult male 01day    3 adult male 05day    2 adult male 30day    3 adult female 01day    1 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    7 embryo 12-14hr    12 embryo 14-16hr    21 embryo 16-18hr    19 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    10 larva L2    4 larva L3 12hr old    1 larva L3 puffstage 1-2    1 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    5 white prepupae 12hr    14 white prepupae 24hr    24 pupae 2d postWPP    24 pupae 3d postWPP    12 pupae 4d postWPP    3 adult male 01day    3 adult male 05day    2 adult male 30day    3 adult female 01day    1 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    7 embryo 12-14hr    12 embryo 14-16hr    21 embryo 16-18hr    19 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    10 larva L2    4 larva L3 12hr old    1 larva L3 puffstage 1-2    1 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    5 white prepupae 12hr    14 white prepupae 24hr    24 pupae 2d postWPP    24 pupae 3d postWPP    12 pupae 4d postWPP    3 adult male 01day    3 adult male 05day    2 adult male 30day    3 adult female 01day    1 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    7 embryo 12-14hr    12 embryo 14-16hr    21 embryo 16-18hr    19 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    10 larva L2    4 larva L3 12hr old    1 larva L3 puffstage 1-2    1 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    5 white prepupae 12hr    14 white prepupae 24hr    24 pupae 2d postWPP    24 pupae 3d postWPP    12 pupae 4d postWPP    3 adult male 01day    3 adult male 05day    2 adult male 30day    3 adult female 01day    1 adult female 05day    0 adult female 30day    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    7 embryo 12-14hr    12 embryo 14-16hr    21 embryo 16-18hr    19 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    10 larva L2    4 larva L3 12hr old    1 larva L3 puffstage 1-2    1 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    5 white prepupae 12hr    14 white prepupae 24hr    24 pupae 2d postWPP    24 pupae 3d postWPP    12 pupae 4d postWPP    3 adult male 01day    3 adult male 05day    2 adult male 30day    3 adult female 01day    1 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    7 embryo 12-14hr    12 embryo 14-16hr    21 embryo 16-18hr    19 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    10 larva L2    4 larva L3 12hr old    1 larva L3 puffstage 1-2    1 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    5 white prepupae 12hr    14 white prepupae 24hr    24 pupae 2d postWPP    24 pupae 3d postWPP    12 pupae 4d postWPP    3 adult male 01day    3 adult male 05day    2 adult male 30day    3 adult female 01day    1 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    7 embryo 12-14hr    12 embryo 14-16hr    21 embryo 16-18hr    19 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    10 larva L2    4 larva L3 12hr old    1 larva L3 puffstage 1-2    1 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    5 white prepupae 12hr    14 white prepupae 24hr    24 pupae 2d postWPP    24 pupae 3d postWPP    12 pupae 4d postWPP    3 adult male 01day    3 adult male 05day    2 adult male 30day    3 adult female 01day    1 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    7 embryo 12-14hr    12 embryo 14-16hr    21 embryo 16-18hr    19 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    10 larva L2    4 larva L3 12hr old    1 larva L3 puffstage 1-2    1 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    5 white prepupae 12hr    14 white prepupae 24hr    24 pupae 2d postWPP    24 pupae 3d postWPP    12 pupae 4d postWPP    3 adult male 01day    3 adult male 05day    2 adult male 30day    3 adult female 01day    1 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    5 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    6 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    6 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    6 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    6 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    6 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    6 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    6 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    6 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_29 mE1_20_mRNA_expression_cluster_11
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038837 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3822-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG3822f03502 viable, with Dcr-2Scer\UAS.cDa, Scer\GAL4e22c, Scer\GAL4sqh.PW CG3822GD3677 viable, with Scer\GAL4pnr-MD237 CG3822GD3677 Sterility Allele fertile CG3822f03502 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG3822 Class Mutagen Stocks Known lesion CG3822f03502 piggyBac transposase 2 -- CG3822MB01010 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG3822 Class Mutagen Stocks Known lesion CG3822GD3677 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG3822JF01873 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG3822KK102490 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD3677} NA P{KK102490} NA P{TRiP.JF01873} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{WH}CG3822f03502 NA insertion of enhancer trap binary system Mi{ET1}CG3822MB01010 No
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
extracellular-glutamate-gated ion channel activity inferred from electronic annotation with InterPro:IPR001320, InterPro:IPR001508, InterPro:IPR019594 (FlyBase Curators et al., 2004-) kainate selective glutamate receptor activity inferred from sequence or structural similarity (Littleton and Ganetzky, 2000) inferred from sequence or structural similarity with human GRIK1 (Curators, 2008--)
Biological Process
CV term Evidence References
ion transport inferred from electronic annotation with InterPro:IPR001508 (FlyBase Curators et al., 2004-) regulation of synaptic activity inferred from sequence or structural similarity with GluRIIA (Curators, 2008--)
Cellular Component
CV term Evidence References
plasma membrane inferred from sequence or structural similarity with GluRIIA (Curators, 2008--)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG3822 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0038837
Orthologs
OrthoDB Orthologs (85) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6VX2QN Dipteran inclusive ortholog search EOG68SH23 Insect inclusive ortholog search EOG6GHXJ1 Arthropod inclusive ortholog search EOG6S4MX2 Metazoa inclusive ortholog search EOG6B61ZS
Orthologs in Drosophila Species (EOG6VX2QN)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG3822     Drosophila simulans   Dsim\GD20025 Y   Drosophila sechellia   Dsec\GM23151 Y   Drosophila erecta   Dere\GG15059 Y   Drosophila yakuba   Dyak\GE25031 Y   Drosophila ananassae   Dana\GF17009 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA17711 Y   Drosophila persimilis   Dper\GL23254 Y   Drosophila willistoni   Dwil\GK22690 Y   Drosophila virilis   Dvir\GJ24267 Y   Drosophila mojavensis   Dmoj\GI22149 Y   Drosophila grimshawi   Dgri\GH17276 Y
Orthologs in non-Drosophila Dipterans (EOG68SH23)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL002506 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL002538 Y Anopheles gambiae Malaria mosquito  Agam\AGAP000801 Y Anopheles gambiae Malaria mosquito  Agam\AGAP000803 Y Anopheles gambiae Malaria mosquito  Agam\AGAP012447 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ018689 Y
Orthologs in non-Dipteran Insects (EOG6GHXJ1)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB49273 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG015255 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH18021 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO19233 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL22071 Y Linepithema humile Argentine ant  Lhum\LH24044 Y Linepithema humile Argentine ant  Lhum\LH24045 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB25136 Y Solenopsis invicta Red fire ant  Sinv\SINV25300 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI006975 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI087808 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI071399 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI004687 Y Bombyx mori Silkmoth  Bmor\BGIBMGA011529 Y Bombyx mori Silkmoth  Bmor\BGIBMGA011528 Y Pediculus humanus Human body louse  Phum\PHUM253980 Y Pediculus humanus Human body louse  Phum\PHUM518050 Y Tribolium castaneum Red flour beetle  Tcas\TC014487 Y Tribolium castaneum Red flour beetle  Tcas\TC012818 Y Tribolium castaneum Red flour beetle  Tcas\TC000367 Y Tribolium castaneum Red flour beetle  Tcas\TC001185 Y
Orthologs in non-Insect Arthropods (EOG6S4MX2)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\MCM10 Y Daphnia pulex Water flea  Dpux\KLHDC8A Y Daphnia pulex Water flea  Dpux\H3 Y Ixodes scapularis Deer tick  Isca\ISCW023274 Y Ixodes scapularis Deer tick  Isca\ISCW008265 Y Ixodes scapularis Deer tick  Isca\ISCW012402 Y Ixodes scapularis Deer tick  Isca\ISCW008266 Y Ixodes scapularis Deer tick  Isca\ISCW023268 Y
Orthologs in non-Arthropod Metazoa (EOG6B61ZS)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\glr-5 Y Caenorhabditis elegans Nematode  Cele\glr-3 Y Caenorhabditis elegans Nematode  Cele\glr-4 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015492gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_014664gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_028455gn Y Danio rerio Zebrafish  Drer\ENSDARG00000077715 Y Danio rerio Zebrafish  Drer\ENSDARG00000040627 Y Danio rerio Zebrafish  Drer\ENSDARG00000074515 Y Danio rerio Zebrafish  Drer\si:ch211-264f5.8 Y Danio rerio Zebrafish  Drer\grik5 Y Danio rerio Zebrafish  Drer\ENSDARG00000091173 Y Danio rerio Zebrafish  Drer\grik4 Y Danio rerio Zebrafish  Drer\grik1a Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000013277 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000014704 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000031503 Y Xenopus tropicalis Western clawed frog  Xtro\grik1 Y Xenopus tropicalis Western clawed frog  Xtro\grik4 Y Gallus gallus Domestic chicken  Ggal\GRIK1 Y Gallus gallus Domestic chicken  Ggal\GRIK4 Y Gallus gallus Domestic chicken  Ggal\GRIK3 Y Gallus gallus Domestic chicken  Ggal\GRIK2 Y Mus musculus House mouse  Mmus\Grik2 Y Mus musculus House mouse  Mmus\Grik3 Y Mus musculus House mouse  Mmus\Grik5 Y Mus musculus House mouse  Mmus\Grik1 Y Mus musculus House mouse  Mmus\Grik4 Y Rattus norvegicus Norway rat  Rnor\Grik3 Y Rattus norvegicus Norway rat  Rnor\Grik4 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000000368 Y Rattus norvegicus Norway rat  Rnor\Grik5 Y Rattus norvegicus Norway rat  Rnor\Grik1 Y Homo sapiens Human  Hsap\GRIK1 Y Homo sapiens Human  Hsap\GRIK2 Y Homo sapiens Human  Hsap\GRIK4 Y Homo sapiens Human  Hsap\GRIK3 Y Homo sapiens Human  Hsap\GRIK5 Y
Human Orthologs (5)
Gene OMIM HGNC Hsap\GRIK1     Hsap\GRIK2     Hsap\GRIK4     Hsap\GRIK3     Hsap\GRIK5
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD20025 Drosophila sechellia Dsec\GM23151 Drosophila erecta Dere\GG15059 Drosophila yakuba Dyak\GE25031 Drosophila ananassae Dana\GF17009 Drosophila pseudoobscura pseudoobscura Dpse\GA17711 Drosophila persimilis Dper\GL23254 Drosophila willistoni Dwil\GK22690 Drosophila virilis Dvir\GJ24267 Drosophila mojavensis Dmoj\GI22149 Drosophila grimshawi Dgri\GH17276
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	18663 w1118; PBac{WH}CG3822f03502 25852 y1 v1; P{TRiP.JF01873}attP2 22962 y1 w67c23; Mi{ET1}CG3822MB01010
Harvard	- PBac{WH}CG3822f03502
VDRC	v40985 w1118 P{GD3677}v40985
Genomic Clones ( 1 )
	BACR19P12 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 65 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE06730
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	5355 11048 15805 19137 47020 67169 67393 84007 118613 156306 CK01.73B.C10 EK057832 EK111056 EK124457 EK127605 EK171152 EK196051 EK196122 EK218424 EK259201 RP003059829 RP003063107 RP003067522 RP003107974 RP003110187 RP003117915 RP003155813 RP003156226 RP003163685 RP003164171 RP003197388 RP003200571 RP003203071 RP003223593 RP003291372 RP003294863 RP003296883 RP003314665 RP003333305 RP003334909 RP003343877 RP003349749 RP003392549 RP003447790 RP003461444 RP003472599 RP003484015 RP003494305 RP003495072 RP003495933 RP003505666 RP003529092 RP003541854 RP003546236 RP003547726 RP003560248 RP003569573 RP003579281 RP003582338 RP003589429 RP003610853 RP003644659 RP003668849 RP003678174
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0038837 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42473
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_142668 RefSeq (Proteins) • NP_650925 DDBJ / EMBL / GenBank • AAF55818 AAM50963 AY119103 BI166565 CZ486077 CZ486078 Entrez Gene - A searchable database of RefSeq genes. • 42473 UniProtKB/TrEMBL • Q8MS48 Q9VDH5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Ionotropic glutamate receptor (IPR001320) NMDA receptor (IPR001508) Extracellular ligand-binding receptor (IPR001828) Glutamate receptor, L-glutamate/glycine-binding (IPR019594)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0038837 DRSC - Results from RNAi screens. • FBgn0038837 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038837 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3822-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0038837 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42473 modMine - Data generated by the modENCODE project. • FBgn0038837
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	CG3822 (Guan et al., 2011, Lee et al., 2009, Perkins et al., 1.15.2009, Benton et al., 2009, Croset et al., 2010, Croset et al., 2010, Keleman et al., 2009.8.5, Tsubouchi et al., 2012) CT12759 (Littleton and Ganetzky, 2000) DmelCG3822 (Croset et al., 2010)
Name Synonym
Secondary FlyBase IDs
References ( 25 )
Generate a list of	All references relating to this gene ( 25 )
List References by type	Research paper  ( 7 ) Supplementary material  ( 5 ) Personal communication to FlyBase  ( 9 ) FlyBase analysis  ( 2 ) Curated genome annotation  ( 1 )
Recent research papers ( 2 )
	Baycin-Hizal et al., 2011, J. Proteome Res. 10(6): 2777--2784 GlycoFly: A Database of Drosophila N-linked Glycoproteins Identified Using SPEG-MS Techniques. [FBrf0213834] Guan et al., 2011, Learn. Mem. 18(4): 191--206 Altered gene regulation and synaptic morphology in Drosophila learning and memory mutants. [FBrf0213277] Show all research papers ...