Gene Dmel\dmrt93B

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General Information

Symbol

Dmel\dmrt93B

Species

D. melanogaster

Name

doublesex-Mab related 93B

Annotation symbol

CG5737

Feature type

protein_coding_gene

FlyBase ID

FBgn0038851

Gene Model Status

Current

Stock availability

5 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

93B10-93B10

Sequence location

3R:16,899,729..16,902,520 [+]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

The gene doublesex-Mab related 93B is referred to in FlyBase by the symbol Dmel\dmrt93B (CG5737, FBgn0038851). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: sex differentiation; regulation of transcription, DNA-dependent. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: DM DNA-binding; DMRT/protein doublesex/protein male abnormal 3; DMRTA motif. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very low expression to a trough of no expression detected. Peak expression observed within 06-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1632729_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of dmrt93B. Gene sequence location is 3R:16899729..16902520.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

93B10-93B10

Limits computationally determined from genome sequence between P{PZ}Atpα⁰¹¹⁶⁴ and P{PZ}mod(mdg4)⁰⁷⁰³⁸&P{lacW}mod(mdg4)^L3101

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\dmrt93B for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.48

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

dmrt93B-RA

FBtr0084007

NM_079704

978

325

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

dmrt93B-PA

FBpp0083410

35.6

325

9.51

NP_524428

AAF55843

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

DM DNA-binding (IPR001275)

DMRTA motif (IPR005173)

DMRT/protein doublesex/protein male abnormal 3 (IPR026607)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q9VDF1

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 13 -- 16

embryonic frontal ganglion

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		7.775
Larval Midgut		29.4
Larval Hindgut		9.4
Larval Malpighian Tubules		14.8
Larval Fat Body		30.9
Larval Salivary Gland		7
Larval Trachea		9.5
Larval Carcass		24.4
Adult Head		6.8
Adult Eye		3.675
Adult Brain		8.5
Adult Thoracic-Abdominal Ganglion		10.4
Adult Crop		13.7
Adult Midgut		16
Adult Hindgut		13.1
Adult Malpighian Tubules		15.6
Adult Fat Body		15.5
Adult Salivary Gland		30.4
Adult Heart		2
Adult VirginFemale Spermatheca		6.2
Adult InseminatedFemale Spermatheca		8.7
Adult Ovary		6.3
Adult Testis		35.4
Adult Male Accessory Gland		15.4
Adult Carcass		28.8
Expression Level Scale		None Low

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		7.775
Larval Midgut		29.4
Larval Hindgut		9.4
Larval Malpighian Tubules		14.8
Larval Fat Body		30.9
Larval Salivary Gland		7
Larval Trachea		9.5
Larval Carcass		24.4
Adult Head		6.8
Adult Eye		3.675
Adult Brain		8.5
Adult Thoracic-Abdominal Ganglion		10.4
Adult Crop		13.7
Adult Midgut		16
Adult Hindgut		13.1
Adult Malpighian Tubules		15.6
Adult Fat Body		15.5
Adult Salivary Gland		30.4
Adult Heart		2
Adult VirginFemale Spermatheca		6.2
Adult InseminatedFemale Spermatheca		8.7
Adult Ovary		6.3
Adult Testis		35.4
Adult Male Accessory Gland		15.4
Adult Carcass		28.8
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		7.775
Larval Midgut		29.4
Larval Hindgut		9.4
Larval Malpighian Tubules		14.8
Larval Fat Body		30.9
Larval Salivary Gland		7
Larval Trachea		9.5
Larval Carcass		24.4
Adult Head		6.8
Adult Eye		3.675
Adult Brain		8.5
Adult Thoracic-Abdominal Ganglion		10.4
Adult Crop		13.7
Adult Midgut		16
Adult Hindgut		13.1
Adult Malpighian Tubules		15.6
Adult Fat Body		15.5
Adult Salivary Gland		30.4
Adult Heart		2
Adult VirginFemale Spermatheca		6.2
Adult InseminatedFemale Spermatheca		8.7
Adult Ovary		6.3
Adult Testis		35.4
Adult Male Accessory Gland		15.4
Adult Carcass		28.8
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		7.775
Larval Midgut		29.4
Larval Hindgut		9.4
Larval Malpighian Tubules		14.8
Larval Fat Body		30.9
Larval Salivary Gland		7
Larval Trachea		9.5
Larval Carcass		24.4
Adult Head		6.8
Adult Eye		3.675
Adult Brain		8.5
Adult Thoracic-Abdominal Ganglion		10.4
Adult Crop		13.7
Adult Midgut		16
Adult Hindgut		13.1
Adult Malpighian Tubules		15.6
Adult Fat Body		15.5
Adult Salivary Gland		30.4
Adult Heart		2
Adult VirginFemale Spermatheca		6.2
Adult InseminatedFemale Spermatheca		8.7
Adult Ovary		6.3
Adult Testis		35.4
Adult Male Accessory Gland		15.4
Adult Carcass		28.8
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		7.775
Larval Midgut		29.4
Larval Hindgut		9.4
Larval Malpighian Tubules		14.8
Larval Fat Body		30.9
Larval Salivary Gland		7
Larval Trachea		9.5
Larval Carcass		24.4
Adult Head		6.8
Adult Eye		3.675
Adult Brain		8.5
Adult Thoracic-Abdominal Ganglion		10.4
Adult Crop		13.7
Adult Midgut		16
Adult Hindgut		13.1
Adult Malpighian Tubules		15.6
Adult Fat Body		15.5
Adult Salivary Gland		30.4
Adult Heart		2
Adult VirginFemale Spermatheca		6.2
Adult InseminatedFemale Spermatheca		8.7
Adult Ovary		6.3
Adult Testis		35.4
Adult Male Accessory Gland		15.4
Adult Carcass		28.8
Expression Level Scale		None Low

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		7.775
Larval Midgut		29.4
Larval Hindgut		9.4
Larval Malpighian Tubules		14.8
Larval Fat Body		30.9
Larval Salivary Gland		7
Larval Trachea		9.5
Larval Carcass		24.4
Adult Head		6.8
Adult Eye		3.675
Adult Brain		8.5
Adult Thoracic-Abdominal Ganglion		10.4
Adult Crop		13.7
Adult Midgut		16
Adult Hindgut		13.1
Adult Malpighian Tubules		15.6
Adult Fat Body		15.5
Adult Salivary Gland		30.4
Adult Heart		2
Adult VirginFemale Spermatheca		6.2
Adult InseminatedFemale Spermatheca		8.7
Adult Ovary		6.3
Adult Testis		35.4
Adult Male Accessory Gland		15.4
Adult Carcass		28.8
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		7.775
Larval Midgut		29.4
Larval Hindgut		9.4
Larval Malpighian Tubules		14.8
Larval Fat Body		30.9
Larval Salivary Gland		7
Larval Trachea		9.5
Larval Carcass		24.4
Adult Head		6.8
Adult Eye		3.675
Adult Brain		8.5
Adult Thoracic-Abdominal Ganglion		10.4
Adult Crop		13.7
Adult Midgut		16
Adult Hindgut		13.1
Adult Malpighian Tubules		15.6
Adult Fat Body		15.5
Adult Salivary Gland		30.4
Adult Heart		2
Adult VirginFemale Spermatheca		6.2
Adult InseminatedFemale Spermatheca		8.7
Adult Ovary		6.3
Adult Testis		35.4
Adult Male Accessory Gland		15.4
Adult Carcass		28.8
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		7.775
Larval Midgut		29.4
Larval Hindgut		9.4
Larval Malpighian Tubules		14.8
Larval Fat Body		30.9
Larval Salivary Gland		7
Larval Trachea		9.5
Larval Carcass		24.4
Adult Head		6.8
Adult Eye		3.675
Adult Brain		8.5
Adult Thoracic-Abdominal Ganglion		10.4
Adult Crop		13.7
Adult Midgut		16
Adult Hindgut		13.1
Adult Malpighian Tubules		15.6
Adult Fat Body		15.5
Adult Salivary Gland		30.4
Adult Heart		2
Adult VirginFemale Spermatheca		6.2
Adult InseminatedFemale Spermatheca		8.7
Adult Ovary		6.3
Adult Testis		35.4
Adult Male Accessory Gland		15.4
Adult Carcass		28.8
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	6.8
NA	Eye	3.675
NA	Brain	8.5
7.775	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	no informative data
NA	Crop	no informative data
no informative data	Midgut	no informative data
9.4	Hindgut	no informative data
no informative data	Malpighian Tubules	no informative data
no informative data	Fat Body	no informative data
7	Salivary Gland	no informative data
NA	Heart	2
9.5	Trachea	NA
NA	VirginFemale Spermatheca	6.2
NA	InseminatedFemale Spermatheca	8.7
NA	Ovary	6.3
NA	Testis	35.4
NA	Male Accessory Gland	no informative data
no informative data	Carcass	no informative data

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		0
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		1
fat body, white prepupae		0
fat body, pupae P8		0
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		0
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		0
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		1
fat body, white prepupae		0
fat body, pupae P8		0
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		0
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		0
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		1
fat body, white prepupae		0
fat body, pupae P8		0
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		0
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		1
fat body, white prepupae		0
fat body, pupae P8		0
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		0
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		0
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		1
fat body, white prepupae		0
fat body, pupae P8		0
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		0
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		0
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		1
fat body, white prepupae		0
fat body, pupae P8		0
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		0
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		0
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		1
fat body, white prepupae		0
fat body, pupae P8		0
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		0
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		1
fat body, white prepupae		0
fat body, pupae P8		0
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Treatments RNA-Seq

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(Graveley et al., 2011)

mE1_20_mRNA_expression_cluster_08

External Data & Images

Linkouts

BDGP expression data

•

PCSP6015

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0038851

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG5737-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable, with Scer\GAL4^pnr-MD237

dmrt93B^GD4332

Phenotype manifest in

Allele

Classical Alleles ( 1 )

For All Classical Alleles Show

Allele of dmrt93B	Class	Mutagen	Stocks	Known lesion
dmrt93B^MB02937			1	--

Alleles Carried on Transgenic Constructs ( 3 )

For All Alleles Carried on Transgenic Constructs Show

Allele of dmrt93B	Mutagen	Stocks	Known lesion
dmrt93B^GD4332	in vitro construct - RNAi in vitro construct - regulatory fusion	3	Yes
dmrt93B^JF02735	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
dmrt93B^NIG.5737R	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Disrupted in

Df(3R)Exel6272

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD4332}

P{NIG.5737R}

P{TRiP.JF02735}

Insertions

Type of insertions

Name

Expression data

insertion of enhancer trap binary system

Mi{ET1}dmrt93B^MB02937

insertion of mobile activating element

P{GSV1}EP-572^EP-572

Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 5 terms )

Molecular Function

CV term

Evidence

References

sequence-specific DNA binding

inferred from electronic annotation with InterPro:IPR001275

(FlyBase Curators et al., 2004-)

sequence-specific DNA binding transcription factor activity

inferred from sequence or structural similarity with EMBL:AF029676

(FlyBase, 1992-)

Biological Process

CV term

Evidence

References

regulation of transcription, DNA-dependent

inferred from electronic annotation with InterPro:IPR001275

(FlyBase Curators et al., 2004-)

sex differentiation

inferred from electronic annotation with InterPro:IPR001275

(FlyBase Curators et al., 2004-)

Cellular Component

CV term

Evidence

References

nucleus

inferred from sequence or structural similarity with EMBL:AF029676

(FlyBase, 1992-)

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

dmrt93B allele

Gene

References

External Data

Linkouts

BioGRID - A database of protein and genetic interactions

•

67465

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0038851

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

42494

Orthologs

OrthoDB Orthologs (34) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG6RNBVF

Dipteran inclusive ortholog search

EOG6RJG9B

Insect inclusive ortholog search

EOG68PKFW

Arthropod inclusive ortholog search

EOG6GQNMN

Metazoa inclusive ortholog search

EOG6CVV1R

Orthologs in Drosophila Species (EOG6RNBVF)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA19095

Drosophila persimilis

Dper\GL11942

Drosophila willistoni

Dwil\GK14181

Drosophila virilis

Dvir\GJ10903

Drosophila mojavensis

Dmoj\GI24085

Drosophila grimshawi

Dgri\GH18276

Orthologs in non-Drosophila Dipterans (EOG6RJG9B)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL004696

Anopheles gambiae

Malaria mosquito

Agam\AGAP001388

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ003316

Orthologs in non-Dipteran Insects (EOG68PKFW)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\LOC409455

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG015714

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH19753

Atta cephalotes

Leafcutter ant

Acep\ACEP15390

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO13095

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL19184

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL19185

Linepithema humile

Argentine ant

Lhum\LH13461

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB18113

Solenopsis invicta

Red fire ant

Sinv\SINV13886

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI007850

Pediculus humanus

Human body louse

Phum\PHUM041260

Orthologs in non-Insect Arthropods (EOG6GQNMN)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Daphnia pulex

Water flea

Dpux\Lamb3

Ixodes scapularis

Deer tick

Isca\ISCW007589

Ixodes scapularis

Deer tick

Isca\ISCW008284

Ixodes scapularis

Deer tick

Isca\ISCW023482

Ixodes scapularis

Deer tick

Isca\ISCW007591

Ixodes scapularis

Deer tick

Isca\ISCW002258

Orthologs in non-Arthropod Metazoa (EOG6CVV1R)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Caenorhabditis elegans

Nematode

Cele\dmd-4

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_028120gn

Human Orthologs (0)

Gene

OMIM

HGNC

AAA Orthologs (10) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA19095

Drosophila persimilis

Dper\GL11942

Drosophila willistoni

Dwil\GK14181

Drosophila virilis

Dvir\GJ10903

Drosophila mojavensis

Dmoj\GI24085

Drosophila grimshawi

Dgri\GH18276

Stocks & Reagents

Stocks Listed in FlyBase ( 5 )

Bloomington

27657

y¹ v¹; P{TRiP.JF02735}attP2

23594

w¹¹¹⁸; Mi{ET1}dmrt93B^MB02937

VDRC

v41047

w¹¹¹⁸; P{GD4332}v41047

v41048

w¹¹¹⁸; P{GD4332}v41048

v49213

w¹¹¹⁸; P{GD4332}v49213

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 1 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones