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Gene Dmel\sec15

General Information
Symbol	Dmel\sec15	Species	D. melanogaster
Name	sec15	Annotation symbol	CG7034
Feature type	protein_coding_gene	FlyBase ID	FBgn0038856
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	93B12-93B12	Sequence location	3R:16,930,943..16,933,686 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene sec15 is referred to in FlyBase by the symbol Dmel\sec15 (CG7034, FBgn0038856). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: chaeta development; phototaxis; border follicle cell migration; axon guidance; endocytic recycling. 13 alleles are reported. The phenotype of these alleles is annotated with: border follicle cell. It has one annotated transcript and one annotated polypeptide. Protein features are: Exocyst complex subunit Sec15-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult thoracico-abdominal ganglion, larval Malpighian tubules, larval salivary gland, adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1636866_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of sec15. Gene sequence location is 3R:16930943..16933686.
External Summaries
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	References Williamson et al., 2010, J. Cell Biol. 189(5): 885--899 Sequence features HFA16179 BKN21759
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 93B12-93B12   Limits computationally determined from genome sequence between P{PZ}Atpα01164 and P{PZ}mod(mdg4)07038&P{lacW}mod(mdg4)L3101
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\sec15 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) sec15-RA FBtr0084034  NM_142685   2616   766
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein sec15-PA   FBpp0083436   88.7   766   6.37     NP_650942   AAF55848
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Exocyst complex subunit Sec15-like (IPR007225)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF55848   BF502056   BI369294   BI637790   BT003492 AAO39495   CK660488   CO153204   CO181255   CO186340   CO275099   CO282937   CO283753   CO302680   CO305905   CO319780   CO325817   EC078777   EC080029   EC085896   EC227485   EC232674   EC234095   EC237475   EC249305   EC250422   EC253018   EC263629   EV577495   GH748559   GH748974   GH749700   GH752259   GH752849   GH755804   GH757681   GH758611   GH759555   GH760223   GH761076   GH770285   GH771346   GH772991   GH774489   GH777499   GH781461   GH783516   GH784234   GH784814   GH787442   GH788464   GH788889   GH789124   GH789137   GH789176   GH789985   GH791830   GH791975   GH793952   GH795211   GH795632   GH797138   GH799320   GH801230   GH801843   GH802416   GH803872   GH804052   GH805212   GH807184   GH807222   GH808382   GH809022   GH811023   GH811367   GH814134   GH816036   GH818133   GH819427   GH819732   GH820737   GH822280   GH824300   GH824576   GH827385   GH827814   GH829175   GH830212   GH830457   GH831299   GH833122   GH837636   GH838454   GH839645   GH845306   GH845409   GH847969   GH848431   GH849458   GH850024   GH851436   GH853636   GH854351   GH854439   GH854814   GH855752   GH856647   GH858455   GH859495   GH859946   GH861647   GH865845   GH869660   GH869867   GH870705   GH872955   GH873690   GH875976   GH877620   GH879162   GH882480   GH882828   GH883640   GH884118   GH885980   GH886520   GH888239   GH888414   GH889008   GH890034   GH891171   GH893327   GH894270   GH895206   GH898690   GH906772   GH907374   GH908013   GH908251   GH909403   GH910142   GH911517   GH911597   GH913012   GH913456   GH913503   GH916496   GH921275   GH923090   GH925053   GH926356   GH929868   GH929988   GH932263   GH933766   GH934168   GH935457   GH936040   GH937637   GH938383   GH938662
UniProtKB/Swiss-Prot	Q9VDE6
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0038856    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0038856 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0038856 expression level Developmental Stage   Expression Level embryo 00-02hr    2866 embryo 02-04hr    820 embryo 04-06hr    603 embryo 06-08hr    892 embryo 08-10hr    835 embryo 10-12hr    951 embryo 12-14hr    709 embryo 14-16hr    578 embryo 16-18hr    490 embryo 18-20hr    336 embryo 20-22hr    293 embryo 22-24hr    337 larva L1    382 larva L2    409 larva L3 12hr old    324 larva L3 puffstage 1-2    426 larva L3 puffstage 3-6    593 larva L3 puffstage 7-9    824 white prepupae new    901 white prepupae 12hr    831 white prepupae 24hr    806 pupae 2d postWPP    671 pupae 3d postWPP    456 pupae 4d postWPP    280 adult male 01day    430 adult male 05day    432 adult male 30day    461 adult female 01day    925 adult female 05day    1718 adult female 30day    1755 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2866) embryo 02-04hr  (820) embryo 04-06hr  (603) embryo 06-08hr  (892) embryo 08-10hr  (835) embryo 10-12hr  (951) embryo 12-14hr  (709) embryo 14-16hr  (578) embryo 16-18hr  (490) embryo 18-20hr  (336) embryo 20-22hr  (293) embryo 22-24hr  (337) larva L1  (382) larva L2  (409) larva L3 12hr old  (324) larva L3 puffstage 1-2  (426) larva L3 puffstage 3-6  (593) larva L3 puffstage 7-9  (824) white prepupae new  (901) white prepupae 12hr  (831) white prepupae 24hr  (806) pupae 2d postWPP  (671) pupae 3d postWPP  (456) pupae 4d postWPP  (280) adult male 01day  (430) adult male 05day  (432) adult male 30day  (461) adult female 01day  (925) adult female 05day  (1718) adult female 30day  (1755) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2866) embryo 02-04hr    820 embryo 04-06hr    603 embryo 06-08hr    892 embryo 08-10hr    835 embryo 10-12hr    951 embryo 12-14hr    709 embryo 14-16hr    578 embryo 16-18hr    490 embryo 18-20hr    336 embryo 20-22hr    293 embryo 22-24hr    337 larva L1    382 larva L2    409 larva L3 12hr old    324 larva L3 puffstage 1-2    426 larva L3 puffstage 3-6    593 larva L3 puffstage 7-9    824 white prepupae new    901 white prepupae 12hr    831 white prepupae 24hr    806 pupae 2d postWPP    671 pupae 3d postWPP    456 pupae 4d postWPP    280 adult male 01day    430 adult male 05day    432 adult male 30day    461 adult female 01day    925 adult female 05day  (1718) adult female 30day  (1755) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2866 embryo 02-04hr    820 embryo 04-06hr    603 embryo 06-08hr    892 embryo 08-10hr    835 embryo 10-12hr    951 embryo 12-14hr    709 embryo 14-16hr    578 embryo 16-18hr    490 embryo 18-20hr    336 embryo 20-22hr    293 embryo 22-24hr    337 larva L1    382 larva L2    409 larva L3 12hr old    324 larva L3 puffstage 1-2    426 larva L3 puffstage 3-6    593 larva L3 puffstage 7-9    824 white prepupae new    901 white prepupae 12hr    831 white prepupae 24hr    806 pupae 2d postWPP    671 pupae 3d postWPP    456 pupae 4d postWPP    280 adult male 01day    430 adult male 05day    432 adult male 30day    461 adult female 01day    925 adult female 05day    1718 adult female 30day    1755 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2866 embryo 02-04hr    820 embryo 04-06hr    603 embryo 06-08hr    892 embryo 08-10hr    835 embryo 10-12hr    951 embryo 12-14hr    709 embryo 14-16hr    578 embryo 16-18hr    490 embryo 18-20hr    336 embryo 20-22hr    293 embryo 22-24hr    337 larva L1    382 larva L2    409 larva L3 12hr old    324 larva L3 puffstage 1-2    426 larva L3 puffstage 3-6    593 larva L3 puffstage 7-9    824 white prepupae new    901 white prepupae 12hr    831 white prepupae 24hr    806 pupae 2d postWPP    671 pupae 3d postWPP    456 pupae 4d postWPP    280 adult male 01day    430 adult male 05day    432 adult male 30day    461 adult female 01day    925 adult female 05day    1718 adult female 30day    1755 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0038856 expression level Developmental Stage   Expression Level embryo 00-02hr    2866 embryo 02-04hr    820 embryo 04-06hr    603 embryo 06-08hr    892 embryo 08-10hr    835 embryo 10-12hr    951 embryo 12-14hr    709 embryo 14-16hr    578 embryo 16-18hr    490 embryo 18-20hr    336 embryo 20-22hr    293 embryo 22-24hr    337 larva L1    382 larva L2    409 larva L3 12hr old    324 larva L3 puffstage 1-2    426 larva L3 puffstage 3-6    593 larva L3 puffstage 7-9    824 white prepupae new    901 white prepupae 12hr    831 white prepupae 24hr    806 pupae 2d postWPP    671 pupae 3d postWPP    456 pupae 4d postWPP    280 adult male 01day    430 adult male 05day    432 adult male 30day    461 adult female 01day    925 adult female 05day    1718 adult female 30day    1755 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2866) embryo 02-04hr  (820) embryo 04-06hr  (603) embryo 06-08hr  (892) embryo 08-10hr  (835) embryo 10-12hr  (951) embryo 12-14hr  (709) embryo 14-16hr  (578) embryo 16-18hr  (490) embryo 18-20hr  (336) embryo 20-22hr  (293) embryo 22-24hr  (337) larva L1  (382) larva L2  (409) larva L3 12hr old  (324) larva L3 puffstage 1-2  (426) larva L3 puffstage 3-6  (593) larva L3 puffstage 7-9  (824) white prepupae new  (901) white prepupae 12hr  (831) white prepupae 24hr  (806) pupae 2d postWPP  (671) pupae 3d postWPP  (456) pupae 4d postWPP  (280) adult male 01day  (430) adult male 05day  (432) adult male 30day  (461) adult female 01day  (925) adult female 05day  (1718) adult female 30day  (1755) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2866) embryo 02-04hr    820 embryo 04-06hr    603 embryo 06-08hr    892 embryo 08-10hr    835 embryo 10-12hr    951 embryo 12-14hr    709 embryo 14-16hr    578 embryo 16-18hr    490 embryo 18-20hr    336 embryo 20-22hr    293 embryo 22-24hr    337 larva L1    382 larva L2    409 larva L3 12hr old    324 larva L3 puffstage 1-2    426 larva L3 puffstage 3-6    593 larva L3 puffstage 7-9    824 white prepupae new    901 white prepupae 12hr    831 white prepupae 24hr    806 pupae 2d postWPP    671 pupae 3d postWPP    456 pupae 4d postWPP    280 adult male 01day    430 adult male 05day    432 adult male 30day    461 adult female 01day    925 adult female 05day  1718 adult female 30day  1755 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2866 embryo 02-04hr    820 embryo 04-06hr    603 embryo 06-08hr    892 embryo 08-10hr    835 embryo 10-12hr    951 embryo 12-14hr    709 embryo 14-16hr    578 embryo 16-18hr    490 embryo 18-20hr    336 embryo 20-22hr    293 embryo 22-24hr    337 larva L1    382 larva L2    409 larva L3 12hr old    324 larva L3 puffstage 1-2    426 larva L3 puffstage 3-6    593 larva L3 puffstage 7-9    824 white prepupae new    901 white prepupae 12hr    831 white prepupae 24hr    806 pupae 2d postWPP    671 pupae 3d postWPP    456 pupae 4d postWPP    280 adult male 01day    430 adult male 05day    432 adult male 30day    461 adult female 01day    925 adult female 05day    1718 adult female 30day    1755 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2866 embryo 02-04hr    820 embryo 04-06hr    603 embryo 06-08hr    892 embryo 08-10hr    835 embryo 10-12hr    951 embryo 12-14hr    709 embryo 14-16hr    578 embryo 16-18hr    490 embryo 18-20hr    336 embryo 20-22hr    293 embryo 22-24hr    337 larva L1    382 larva L2    409 larva L3 12hr old    324 larva L3 puffstage 1-2    426 larva L3 puffstage 3-6    593 larva L3 puffstage 7-9    824 white prepupae new    901 white prepupae 12hr    831 white prepupae 24hr    806 pupae 2d postWPP    671 pupae 3d postWPP    456 pupae 4d postWPP    280 adult male 01day    430 adult male 05day    432 adult male 30day    461 adult female 01day    925 adult female 05day    1718 adult female 30day    1755 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0038856    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0038856 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult thoracico-abdominal ganglion, larval Malpighian tubules, larval salivary gland, adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0038856 expression level Tissue   Expression Level Larval Central Nervous System    98.8 Larval Midgut    70.4 Larval Hindgut    94.4 Larval Malpighian Tubules    154.8 Larval Fat Body    72.9 Larval Salivary Gland    133 Larval Trachea    78.85 Larval Carcass    78.7 Adult Head    76.2 Adult Eye    70.825 Adult Brain    96.4 Adult Thoracic-Abdominal Ganglion    102.7 Adult Crop    86.5 Adult Midgut    74.2 Adult Hindgut    81.9 Adult Malpighian Tubules no informative data Adult Fat Body    54.3 Adult Salivary Gland no informative data Adult Heart    74.05 Adult VirginFemale Spermatheca    51.9 Adult InseminatedFemale Spermatheca    60.2 Adult Ovary    224.8 Adult Testis    59.4 Adult Male Accessory Gland    78.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    98.8 Larval Midgut    70.4 Larval Hindgut    94.4 Larval Malpighian Tubules    154.8 Larval Fat Body    72.9 Larval Salivary Gland    133 Larval Trachea    78.85 Larval Carcass    78.7 Adult Head    76.2 Adult Eye    70.825 Adult Brain    96.4 Adult Thoracic-Abdominal Ganglion    102.7 Adult Crop    86.5 Adult Midgut    74.2 Adult Hindgut    81.9 Adult Malpighian Tubules no informative data Adult Fat Body    54.3 Adult Salivary Gland no informative data Adult Heart    74.05 Adult VirginFemale Spermatheca    51.9 Adult InseminatedFemale Spermatheca    60.2 Adult Ovary    224.8 Adult Testis    59.4 Adult Male Accessory Gland    78.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    98.8 Larval Midgut    70.4 Larval Hindgut    94.4 Larval Malpighian Tubules    154.8 Larval Fat Body    72.9 Larval Salivary Gland    133 Larval Trachea    78.85 Larval Carcass    78.7 Adult Head    76.2 Adult Eye    70.825 Adult Brain    96.4 Adult Thoracic-Abdominal Ganglion    102.7 Adult Crop    86.5 Adult Midgut    74.2 Adult Hindgut    81.9 Adult Malpighian Tubules no informative data Adult Fat Body    54.3 Adult Salivary Gland no informative data Adult Heart    74.05 Adult VirginFemale Spermatheca    51.9 Adult InseminatedFemale Spermatheca    60.2 Adult Ovary    224.8 Adult Testis    59.4 Adult Male Accessory Gland    78.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    98.8 Larval Midgut    70.4 Larval Hindgut    94.4 Larval Malpighian Tubules    154.8 Larval Fat Body    72.9 Larval Salivary Gland    133 Larval Trachea    78.85 Larval Carcass    78.7 Adult Head    76.2 Adult Eye    70.825 Adult Brain    96.4 Adult Thoracic-Abdominal Ganglion    102.7 Adult Crop    86.5 Adult Midgut    74.2 Adult Hindgut    81.9 Adult Malpighian Tubules no informative data Adult Fat Body    54.3 Adult Salivary Gland no informative data Adult Heart    74.05 Adult VirginFemale Spermatheca    51.9 Adult InseminatedFemale Spermatheca    60.2 Adult Ovary    224.8 Adult Testis    59.4 Adult Male Accessory Gland    78.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0038856 expression level Tissue   Expression Level Larval Central Nervous System    98.8 Larval Midgut    70.4 Larval Hindgut    94.4 Larval Malpighian Tubules    154.8 Larval Fat Body    72.9 Larval Salivary Gland    133 Larval Trachea    78.85 Larval Carcass    78.7 Adult Head    76.2 Adult Eye    70.825 Adult Brain    96.4 Adult Thoracic-Abdominal Ganglion    102.7 Adult Crop    86.5 Adult Midgut    74.2 Adult Hindgut    81.9 Adult Malpighian Tubules no informative data Adult Fat Body    54.3 Adult Salivary Gland no informative data Adult Heart    74.05 Adult VirginFemale Spermatheca    51.9 Adult InseminatedFemale Spermatheca    60.2 Adult Ovary    224.8 Adult Testis    59.4 Adult Male Accessory Gland    78.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    98.8 Larval Midgut    70.4 Larval Hindgut    94.4 Larval Malpighian Tubules    154.8 Larval Fat Body    72.9 Larval Salivary Gland    133 Larval Trachea    78.85 Larval Carcass    78.7 Adult Head    76.2 Adult Eye    70.825 Adult Brain    96.4 Adult Thoracic-Abdominal Ganglion    102.7 Adult Crop    86.5 Adult Midgut    74.2 Adult Hindgut    81.9 Adult Malpighian Tubules no informative data Adult Fat Body    54.3 Adult Salivary Gland no informative data Adult Heart    74.05 Adult VirginFemale Spermatheca    51.9 Adult InseminatedFemale Spermatheca    60.2 Adult Ovary    224.8 Adult Testis    59.4 Adult Male Accessory Gland    78.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    98.8 Larval Midgut    70.4 Larval Hindgut    94.4 Larval Malpighian Tubules    154.8 Larval Fat Body    72.9 Larval Salivary Gland    133 Larval Trachea    78.85 Larval Carcass    78.7 Adult Head    76.2 Adult Eye    70.825 Adult Brain    96.4 Adult Thoracic-Abdominal Ganglion    102.7 Adult Crop    86.5 Adult Midgut    74.2 Adult Hindgut    81.9 Adult Malpighian Tubules no informative data Adult Fat Body    54.3 Adult Salivary Gland no informative data Adult Heart    74.05 Adult VirginFemale Spermatheca    51.9 Adult InseminatedFemale Spermatheca    60.2 Adult Ovary    224.8 Adult Testis    59.4 Adult Male Accessory Gland    78.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    98.8 Larval Midgut    70.4 Larval Hindgut    94.4 Larval Malpighian Tubules    154.8 Larval Fat Body    72.9 Larval Salivary Gland    133 Larval Trachea    78.85 Larval Carcass    78.7 Adult Head    76.2 Adult Eye    70.825 Adult Brain    96.4 Adult Thoracic-Abdominal Ganglion    102.7 Adult Crop    86.5 Adult Midgut    74.2 Adult Hindgut    81.9 Adult Malpighian Tubules no informative data Adult Fat Body    54.3 Adult Salivary Gland no informative data Adult Heart    74.05 Adult VirginFemale Spermatheca    51.9 Adult InseminatedFemale Spermatheca    60.2 Adult Ovary    224.8 Adult Testis    59.4 Adult Male Accessory Gland    78.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules no informative data Adult Fat Body     Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    76.2   NA  Eye    70.825   NA  Brain    96.4   98.8  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    102.7   NA  Crop    86.5   70.4  Midgut    74.2   94.4  Hindgut    81.9   154.8  Malpighian Tubules    no informative data   72.9  Fat Body    54.3   133  Salivary Gland    no informative data   NA  Heart    74.05   78.85  Trachea    NA   NA  VirginFemale Spermatheca    51.9   NA  InseminatedFemale Spermatheca    60.2   NA  Ovary    224.8   NA  Testis    59.4   NA  Male Accessory Gland    78.1   78.7  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_06
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038856 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7034-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | early third instar larval stage (with sec151) sec153 lethal | early third instar larval stage (with sec152) sec153 lethal | early third instar larval stage (with sec153) sec151 sec152 lethal | pupal stage, with Scer\GAL4pnr-MD237 sec15GD12109 lethal | recessive | second instar larval stage sec153 lethal | second instar larval stage (with Df(3R)e-R1) sec152 Other Phenotypes Allele neuroanatomy defective | somatic clone sec151 sec152 neurophysiology defective | somatic clone sec151 sec152 phototaxis behavior defective | somatic clone sec151 sec152 Phenotype manifest in Allele axon & photoreceptor cell R7 | somatic clone sec151 axon & photoreceptor cell R8 | somatic clone sec151 border follicle cell, with Scer\GAL4c306 sec15VDRC.cUa eo neuron & mesothoracic tergum & pupa | somatic clone | supernumerary sec153 macrochaeta & mesothoracic tergum | somatic clone sec153 medulla | somatic clone sec151 nerve terminal & optic cartridge | somatic clone sec151 nerve terminal & optic cartridge | somatic clone | cell autonomous sec152 optic lobe | somatic clone sec151 thecogen cell & mesothoracic tergum & pupa | somatic clone sec153 tormogen cell & mesothoracic tergum & pupa | somatic clone sec153
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of sec15 Class Mutagen Stocks Known lesion sec151 ethyl methanesulfonate 1 Yes sec152 ethyl methanesulfonate 1 Yes sec153 hypomorphic allele - genetic evidence ethyl methanesulfonate 0 Yes sec15unspecified 0 --
Alleles Carried on Transgenic Constructs ( 9 )
For All Alleles Carried on Transgenic Constructs Show
Allele of sec15 Class Mutagen Stocks Known lesion sec15GD12109 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes sec15JF02649 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes sec15KK101708 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes sec15+t5 in vitro construct - genomic fragment 0 Yes sec15C.Scer\UAS.T:Avic\GFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes sec15N.Scer\UAS.T:Avic\GFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes sec15Scer\UAS.T:Ivir\HA1 in vitro construct - coding region fusion in vitro construct - regulatory fusion 0 Yes sec15tCH322-152E24 in vitro construct - genomic fragment 0 Yes sec15VDRC.cUa in vitro construct - regulatory fusion in vitro construct - RNAi 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)e-R1 (Mehta et al., 2005) Df(3R)Exel6272 (Ryder, 2004.4.26)
Not duplicated in	Df(3R)e-N19 (Mehta et al., 2005)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD12109} NA P{KK101708} NA P{TRiP.JF02649} NA P{UAS-GFP.sec15} NA P{UAS-sec15.GFP} NA P{UAS-sec15.HA} NA characterization construct P{sec15.+t5} NA P{VDRC.sec15.U} NA PBac{CH322-152E24} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 13 unique terms )
Terms Based on Experimental Evidence ( 8 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
axon guidance inferred from mutant phenotype (Mehta et al., 2005) border follicle cell migration inferred from mutant phenotype (Assaker et al., 2010) chaeta development inferred from mutant phenotype (Jafar-Nejad et al., 2005) endocytic recycling inferred from mutant phenotype (Jafar-Nejad et al., 2005) phototaxis inferred from mutant phenotype (Mehta et al., 2005)
Cellular Component
CV term Evidence References
axon terminus inferred from direct assay (Mehta, 2005) cytoplasmic vesicle inferred from direct assay (Mehta, 2005, Jafar-Nejad et al., 2005) endosome inferred from direct assay (Jafar-Nejad et al., 2005)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
neurotransmitter secretion non-traceable author statement (Lloyd et al., 2000) synaptic vesicle docking involved in exocytosis inferred from sequence or structural similarity with UniProtKB:Q8TAG9 (assigned by UniProtKB) (Swiss-Prot Project Members, 2002.6.15) non-traceable author statement (Lloyd et al., 2000) synaptic vesicle targeting inferred from sequence or structural similarity with UniProtKB:Q8TAG9 (assigned by UniProtKB) (Swiss-Prot Project Members, 2002.6.15) non-traceable author statement (Lloyd et al., 2000) vesicle-mediated transport inferred from sequence or structural similarity (Littleton, 2000)
Cellular Component
CV term Evidence References
exocyst inferred from sequence or structural similarity (Littleton, 2000) inferred from sequence or structural similarity with EMBL:AF032668 (FlyBase, 1992-) inferred from sequence or structural similarity with UniProtKB:Q8TAG9 (assigned by UniProtKB) (Swiss-Prot Project Members, 2002.6.15) non-traceable author statement (Lloyd et al., 2000)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions sec15 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 67470 DroID - A comprehensive database of gene and protein interactions. • FBgn0038856 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42499
Orthologs
Genome-wide drosophilid orthologs	Dana\GF18516 Dere\GG14883 Dgri\GH19328 Dmoj\GI23938 Dper\GL22033 Dpse\GA20047 Dsec\GM15101 Dsim\GD20007 Dvir\GJ23727 Dwil\GK13077 Dyak\GE25017
Curated drosophilid orthologs	Dpse\GA20047
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL003736-PA Aedes aegypti (mosquito) AGAP006648-PA Anopheles gambiae (mosquito) XP_393572.2 Apis mellifera (honey bee) XP_001944089.1 Acyrthosiphon pisum (pea aphid) At3g56640.1 Arabidopsis thaliana (wall cress) 84790 Batrachochytrium dendrobatidis (chytrid fungus) 105117 Branchiostoma floridae (lancelet) XP_001893932.1 Brugia malayi (roundworm nematode) BGIBMGA006987-PA Bombyx mori (silk worm) ENSBTAP00000028134 Bos taurus (bovine) CAL0004495 Candida albicans (a form of yeast) CN28790 Caenorhabditis brenneri (small nematode) CBP18417 Caenorhabditis briggsae (nematode) CE37614 Caenorhabditis elegans (worm) ENSCAFP00000011202 Canis familiaris (dog) CAGL0H07909g Candida glabrata (haploid yeast) ENSCINP00000009986 Ciona intestinalis (sea squirt) JA05381 Caenorhabditis japonica (nematode) cn01234 Cryptococcus neoformans (yeast-like fungus) CPIJ005438 Culex pipens (mosquito) ENSCPOP00000003435 Cavia porcellus (guinea pig) RP38507 Caenorhabditis remanei (nematode) ENSCSAVP00000003865 Ciona savignyi (sedentary tunicate) 168993 Capitella spl (polychaete worm) DDB0233959 Dictyostelium discoideum (amoeba) DEHA2G16720g Debaryomyces Hansenii (yeast) 127521 Daphnia pulex (daphnia) ENSDARP00000026158 Danio rerio (zebra fish) ENSECAP00000017092 Equus caballus (horse) XP_656511 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000024865 Gymnopilus aculeatus (mushroom) ENSGALP00000025892 Gallus gallus (chicken) 157969 Hypsipyla robusta (cedar shoot borer) ENSP00000386634 Homo sapiens (human) ISCW004817-PA Ixodes scapularis (deer tick) KLLA0A01023g Kluyveromyces lactis (yeast) 115306 Lottia gigantea (owl limpet) 27374 Monocosta brevicollis (choanoflagellate) ENSMODP00000007986 Monodelphis domestica (gray opossum) ENSMMUP00000014255 Macaca mulatta (rhesus monkey) ENSMUSP00000064332 Mus musculus (house mouse) 20546 Nematostella vectensis (starlet anemone) XP_001600236.1 Nasonia vitripennis (wasp) ENSOANP00000024787 Ornithorynchus anatinus (platypus) ENSORLP00000018160 Oryzias latipes (japanese killifish) LOC_Os10g27990.1 Oryza sativa (asian rice) PHUM000266-PA Pediculus humanus (human body louse) 125337 Physcomitrella patens (moss) ENSPPYP00000013723 Pongo pygmaeus (orangutan) 78856 Phytophthora ramorum (sudden oak death pathogen) 133542 Phytophthora sojae (root rot pathogen) 652542 Populus trichocarpa (black cottonwood) ENSPTRP00000039422 Pan troglodytes (chimpanzee) 4869543 Sorghum bicolor (sorghum) YGL233W Saccharomyces cerevisiae (budding yeast) Smp_146100 Schistosoma mansoni (trematode parasite) SPCC1183.01 Schizosaccharomyces pombe (fission yeast) XP_001197185.1 Strongylocentrotus purpuratus (purple sea urchin) 60734 Trichoplax adhaerens (metazoa) XP_968337.1 Tribolium castaneum (red flour beetle) ENSTNIP00000008190 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000005981 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000039421 Xenopus tropicalis (frog) YALI0F12969g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV14232 LH23594 ISCW004817 FBgn0242107 FBgn0215086 FBgn0210824 FBgn0191490 FBgn0170021 JGI_V11_127521 FBgn0080043 FBgn0159626 FBgn0146663 FBgn0126793 FBgn0107138 FBgn0095534 CPIJ005438 BGIBMGA006987 ACYPI008098 GB13729 AGAP006648 AAEL003736 PB24248 PHUM332580 GLEAN_11021
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	27499 y1 v1; P{TRiP.JF02649}attP2 24889 yd2 w1118 P{ey-FLP.N}2 P{GMR-lacZ.C(38.1)}TPN1; P{neoFRT}82B sec151/TM3, P{GAL4-Kr.C}DC2, P{UAS-GFP.S65T}DC10, Sb1 24890 yd2 w1118 P{ey-FLP.N}2 P{GMR-lacZ.C(38.1)}TPN1; P{neoFRT}82B sec152/TM3, P{GAL4-Kr.C}DC2, P{UAS-GFP.S65T}DC10, Sb1
VDRC	v105126 P{KK101708}VIE-260B v35161 w1118; P{GD12109}v35161 v35162 w1118; P{GD12109}v35162/TM3
Genomic Clones ( 1 )
	BACR20N14 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 157 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE55430
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT17673 LP19106 SD19870
Other clones	14300 45758 61175 118843 146902 176046 184160 214571.64 522166 CK01.20B.B2 Dmel_dig_007107_0672_1512 EC13895 EK018828 EK116443 EK161815 EK164246 EK184710 EK249654 EK280713 EN01464 EP02561 RP003002985 RP003029247 RP003033243 RP003035307 RP003036505 RP003038785 RP003041498 RP003048705 RP003055726 RP003060466 RP003060653 RP003064217 RP003065617 RP003073650 RP003074102 RP003074631 RP003081313 RP003101368 RP003105639 RP003108767 RP003118272 RP003125342 RP003130165 RP003132657 RP003136066 RP003138347 RP003138614 RP003140203 RP003148257 RP003151380 RP003155532 RP003166409 RP003168529 RP003185444 RP003185946 RP003202429 RP003202973 RP003204262 RP003205770 RP003211546 RP003213084 RP003217292 RP003222026 RP003229042 RP003229629 RP003232233 RP003236606 RP003242640 RP003249286 RP003250314 RP003260946 RP003265200 RP003279219 RP003280731 RP003285857 RP003296200 RP003304991 RP003305543 RP003309333 RP003313998 RP003320336 RP003324488 RP003325516 RP003333172 RP003336692 RP003339418 RP003340456 RP003354174 RP003364819 RP003370011 RP003370900 RP003374132 RP003375775 RP003387336 RP003388288 RP003390621 RP003393707 RP003422341 RP003434253 RP003443788 RP003443999 RP003454284 RP003457039 RP003459995 RP003462370 RP003463454 RP003463861 RP003467482 RP003472493 RP003473553 RP003473839 RP003483404 RP003484105 RP003490208 RP003500725 RP003502571 RP003504212 RP003505377 RP003509821 RP003514270 RP003519413 RP003519442 RP003524144 RP003524413 RP003538348 RP003540317 RP003542484 RP003542544 RP003545512 RP003555216 RP003555747 RP003561106 RP003568577 RP003569679 RP003570234 RP003570770 RP003584427 RP003585094 RP003588013 RP003602856 RP003610773 RP003617302 RP003618336 RP003634143 RP003642955 RP003643795 RP003643844 RP003656316 RP003659729 RP003663541 RP003663722 RP003679445
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0038856 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42499
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: sec15 CG7034 (Verstreken and Bellen, 2000.9.4)
Source for database merge of
Additional comments	FlyBase curator comment: the insertion in the "d11525" Exelixis line (P{XP}rtetd11525) was originally assigned to the sec15 gene in FBrf0179797, resulting in the "sec15d11525" (FBal0158687) allele. However, FBrf0184340 shows that the insertion is actually within rtet. (Bloomington Drosophila Stock Center, 2004.11.6)
Other Comments
	S2 cells treated with dsRNA directed against sec15 show normal binding but significantly decreased internalization of E.coli and S.aureus in a phagocytosis assay. (Stuart et al., 2007) dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_142685 RefSeq (Proteins) • NP_650942 DDBJ / EMBL / GenBank • AAF55848 AAO39495 BI369294 BT003492 Entrez Gene - A searchable database of RefSeq genes. • 42499 UniProtKB/Swiss-Prot • Q9VDE6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Exocyst complex subunit Sec15-like (IPR007225)
Linkouts
	BioGRID - A database of protein and genetic interactions • 67470 DroID - A comprehensive database of gene and protein interactions. • FBgn0038856 DRSC - Results from RNAi screens. • FBgn0038856 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038856 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7034-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0038856 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42499 InParanoid A subset of ortholog calls from InParanoid. • AAEL003736-PA Aedes aegypti (mosquito) AGAP006648-PA Anopheles gambiae (mosquito) XP_393572.2 Apis mellifera (honey bee) XP_001944089.1 Acyrthosiphon pisum (pea aphid) At3g56640.1 Arabidopsis thaliana (wall cress) 84790 Batrachochytrium dendrobatidis (chytrid fungus) 105117 Branchiostoma floridae (lancelet) XP_001893932.1 Brugia malayi (roundworm nematode) BGIBMGA006987-PA Bombyx mori (silk worm) ENSBTAP00000028134 Bos taurus (bovine) CAL0004495 Candida albicans (a form of yeast) CN28790 Caenorhabditis brenneri (small nematode) CBP18417 Caenorhabditis briggsae (nematode) CE37614 Caenorhabditis elegans (worm) ENSCAFP00000011202 Canis familiaris (dog) CAGL0H07909g Candida glabrata (haploid yeast) ENSCINP00000009986 Ciona intestinalis (sea squirt) JA05381 Caenorhabditis japonica (nematode) cn01234 Cryptococcus neoformans (yeast-like fungus) CPIJ005438 Culex pipens (mosquito) ENSCPOP00000003435 Cavia porcellus (guinea pig) RP38507 Caenorhabditis remanei (nematode) ENSCSAVP00000003865 Ciona savignyi (sedentary tunicate) 168993 Capitella spl (polychaete worm) DDB0233959 Dictyostelium discoideum (amoeba) DEHA2G16720g Debaryomyces Hansenii (yeast) 127521 Daphnia pulex (daphnia) ENSDARP00000026158 Danio rerio (zebra fish) ENSECAP00000017092 Equus caballus (horse) XP_656511 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000024865 Gymnopilus aculeatus (mushroom) ENSGALP00000025892 Gallus gallus (chicken) 157969 Hypsipyla robusta (cedar shoot borer) ENSP00000386634 Homo sapiens (human) ISCW004817-PA Ixodes scapularis (deer tick) KLLA0A01023g Kluyveromyces lactis (yeast) 115306 Lottia gigantea (owl limpet) 27374 Monocosta brevicollis (choanoflagellate) ENSMODP00000007986 Monodelphis domestica (gray opossum) ENSMMUP00000014255 Macaca mulatta (rhesus monkey) ENSMUSP00000064332 Mus musculus (house mouse) 20546 Nematostella vectensis (starlet anemone) XP_001600236.1 Nasonia vitripennis (wasp) ENSOANP00000024787 Ornithorynchus anatinus (platypus) ENSORLP00000018160 Oryzias latipes (japanese killifish) LOC_Os10g27990.1 Oryza sativa (asian rice) PHUM000266-PA Pediculus humanus (human body louse) 125337 Physcomitrella patens (moss) ENSPPYP00000013723 Pongo pygmaeus (orangutan) 78856 Phytophthora ramorum (sudden oak death pathogen) 133542 Phytophthora sojae (root rot pathogen) 652542 Populus trichocarpa (black cottonwood) ENSPTRP00000039422 Pan troglodytes (chimpanzee) 4869543 Sorghum bicolor (sorghum) YGL233W Saccharomyces cerevisiae (budding yeast) Smp_146100 Schistosoma mansoni (trematode parasite) SPCC1183.01 Schizosaccharomyces pombe (fission yeast) XP_001197185.1 Strongylocentrotus purpuratus (purple sea urchin) 60734 Trichoplax adhaerens (metazoa) XP_968337.1 Tribolium castaneum (red flour beetle) ENSTNIP00000008190 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000005981 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000039421 Xenopus tropicalis (frog) YALI0F12969g Yarrowia lipolytica (nonconventional yeast) Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /sturtevant/sec15-1.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42499 modMine - Data generated by the modENCODE project. • FBgn0038856 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV14232 LH23594 ISCW004817 FBgn0242107 FBgn0215086 FBgn0210824 FBgn0191490 FBgn0170021 JGI_V11_127521 FBgn0080043 FBgn0159626 FBgn0146663 FBgn0126793 FBgn0107138 FBgn0095534 CPIJ005438 BGIBMGA006987 ACYPI008098 GB13729 AGAP006648 AAEL003736 PB24248 PHUM332580 GLEAN_11021
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	3R41 (Mehta et al., 2005) CG7034 (Whitfield et al., 2002, Keleman et al., 2009.8.5, Perkins et al., 2009) dsec15 (Lloyd et al., 2000) Sec15 (Littleton, 2000, Somers and Chia, 2005, Benhra et al., 2010, Gallagher and Knoblich, 2006, Wu et al., 2005, Tong et al., 2011, Williamson et al., 2010) sec15 (Gotta, 2005, Xu and Cohen, 2007, Hiesinger et al., 2006, Stuart et al., 2007, Nurminsky, 2007, Mehta et al., 2005, Mehta, 2005, Langevin et al., 2005, Jafar-Nejad, 2005, Jafar-Nejad et al., 2005, van IJzendoorn, 2006, Leibfried et al., 2008, Venken et al., 2009, Windler and Bilder, 2010, Tong et al., 2010, Guichard et al., 2010, Assaker et al., 2010, Wu et al., 2005) Sec15p (Littleton, 2000)
Name Synonym	sec15
Secondary FlyBase IDs
References ( 44 )
Generate a list of	All references relating to this gene ( 44 )
List References by type	Research paper  ( 20 ) Supplementary material  ( 6 ) Review  ( 2 ) Personal communication to FlyBase  ( 6 ) Abstract  ( 2 ) FlyBase analysis  ( 1 ) Letter  ( 1 ) Meeting report  ( 1 ) Conference report  ( 1 ) Protein sequence record  ( 1 ) Computer file  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 8 )
	Michel et al., 2011, Nat. Commun. 2: 415 Local BMP receptor activation at adherens junctions in the Drosophila germline stem cell niche. [FBrf0214604] Tong et al., 2011, Neuron 71(3): 447--459 Rich Regulates Target Specificity of Photoreceptor Cells and N-Cadherin Trafficking in the Drosophila Visual System via Rab6. [FBrf0214681] Assaker et al., 2010, Proc. Natl. Acad. Sci. U.S.A. 107(52): 22558--22563 Spatial restriction of receptor tyrosine kinase activity through a polarized endocytic cycle controls border cell migration. [FBrf0212585] Benhra et al., 2010, Mol. Biol. Cell 21(12): 2078--2086 Neuralized promotes Basal to apical transcytosis of delta in epithelial cells. [FBrf0211002] Guichard et al., 2010, Nature 467(7317): 854--858 Anthrax toxins cooperatively inhibit endocytic recycling by the Rab11/Sec15 exocyst. [FBrf0212093] Tong et al., 2010, Mol. Biol. Cell 21(5): 802--810 Numb independently antagonizes sanpodo membrane targeting and notch signaling in Drosophila sensory organ precursor cells. [FBrf0210112] Williamson et al., 2010, J. Cell Biol. 189(5): 885--899 A dual function of V0-ATPase a1 provides an endolysosomal degradation mechanism in Drosophila melanogaster photoreceptors. [FBrf0210877] Windler and Bilder, 2010, Curr. Biol. 20(6): 538--543 Endocytic internalization routes required for delta/notch signaling. [FBrf0210409] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...