Ubpy
Please see the GBrowse view of Dmel\Usp8 or the JBrowse view of Dmel\Usp8 for information on other features
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Gene model reviewed during 5.53
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Usp8 using the Feature Mapper tool.
Eye-enriched transcripts determined by ratio of expression level in wild-type heads. versus expression level in so heads.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Usp8 in GBrowse 23-71
3-71
3-73.7
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Ubpy CG5798
Source for identity of: Usp8 Ubpy
Changed symbol from 'Ubpy' to 'Usp8' because: i) The original symbol (from FBrf0211204) was based on the symbol of the mammalian/human ortholog, and this symbol is currently 'USP8'; ii) all other 'Usp' genes in D. melanogaster named for their molecular function/orthology have a 'Usp' prefix and reflect the current HGNC nomenclature of their human orthologs; iii) several key publications refer to this gene as 'Usp8' (FBrf0211204, FBrf0218247, FBrf0219991, FBrf0225968).
Usp8 is required cell autonomously for dendrite pruning in sensory neurons.
Shows particularly robust cycling of transcription in adult heads, as assessed by expression analysis using high density oligonucleotide arrays with probe generated during three 12-point time course experiments over the course of 6 days. Shows significant change of expression pattern in circadian mutant background; increased expression in per01, tim01 and decreased expression in ClkJrk background.
Identified as one of 10 highest fold cycling genes as assessed by expression analysis using high density oligonucleotide arrays with probe generated from adult heads harvested over six time points over the course of a day.
