PSR, dPSR, phosphatidylserine receptor
Gene model reviewed during 5.43
Stop-codon suppression (UGA) postulated; FBrf0216884.
Gene model reviewed during 5.44
Gene model reviewed during 5.49
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\JMJD6 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\JMJD6 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: PSR BEST:LD22859
'CG5383' was originally named 'PSR/phosphatidylserine receptor' based on the nomenclature used for the human homolog at the time (FBrf0178806). That nomenclature has since been shown to be inaccurate/misleading (https://www.uniprot.org/uniprot/Q6NYC1) and so the FlyBase gene symbol/name has been updated to reflect the current human gene nomenclature of 'JMJD6/jumonji domain containing 6'.
PSR is needed in wild-type cells for the death of Minute neighbours in cell competition experiments.
Identification: in a screen for genes required for the phagocytosis of apoptotic cells in the Drosophila embryo using a panel of Drosophila strains carrying genomic deletions. Several candidate deletions were identified that displayed potential defects in this process. One of these was a large deletion that included the Drosophila homolog of the phosphatidylserine receptor (dPSR).
May function to protect from death in Drosophila.