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Gene Dmel\PSR

General Information
Symbol	Dmel\PSR	Species	D. melanogaster
Name	phosphatidylserine receptor	Annotation symbol	CG5383
Feature type	protein_coding_gene	FlyBase ID	FBgn0038948
Gene Model Status	Current	Stock availability	4 publicly available
Also Known As	dPSR
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	94A6-94A6	Sequence location	3R:18,186,504..18,188,255 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene phosphatidylserine receptor is referred to in FlyBase by the symbol Dmel\PSR (CG5383, FBgn0038948). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: negative regulation of apoptosis; cell competition in a multicellular organism; negative regulation of JNK cascade. 6 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; trichogen cell; male genitalia; wing; ommatidium. It has one annotated transcript and one annotated polypeptide. Protein features are: Transcription factor jumonji; Transcription factor jumonji/aspartyl beta-hydroxylase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, adult Malpighian tubules, larval salivary gland, larval trachea, adult ovary, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1640943_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of PSR. Gene sequence location is 3R:18186504..18188255.
External Summaries
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	References Andersen et al., 2010, Mol. Cell. Biol. 30(19): 4744--4755 Sequence features BKN27474 BKN45164 HFA15787
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 94A6-94A6   Limits computationally determined from genome sequence between P{lacW}l(3)L3560L3560 and P{PZ}l(3)rQ178rQ178
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\PSR for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.43
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) PSR-RA FBtr0084239  NM_142769   1752   408
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein PSR-PA   FBpp0083632   47.0   408   9.44     NP_651026   AAF55975
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Transcription factor jumonji/aspartyl beta-hydroxylase (IPR003347) Transcription factor jumonji (IPR013129)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA246248   AA246439   AA264531   AA391007   AA694734   AA696288   AA735370   AA821044   AA940716   AA940950   AA941457   AA941604   AA941818   AA950285   AA951036   AA979250   AE014297 AAF55975   AI292881   AI514315   AI518625   AI531999   AI532244   AW942817   AY051727 AAK93151   BF493489   BF493490   BF495672   BG635243   BI215154   BI232624   BI234244   BI242188   BI355678   BI374423   BI622368   BI641261   BP551595   CO265409   CO295838   CO325393   CO327992   EC066447   EC086708   EC212875   EC244639
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VD28
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0038948    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0038948 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0038948 expression level Developmental Stage   Expression Level embryo 00-02hr    6780 embryo 02-04hr    11796 embryo 04-06hr    11349 embryo 06-08hr    9375 embryo 08-10hr    7291 embryo 10-12hr    6505 embryo 12-14hr    3097 embryo 14-16hr    3958 embryo 16-18hr    2468 embryo 18-20hr    2193 embryo 20-22hr    2536 embryo 22-24hr    2166 larva L1    2539 larva L2    2141 larva L3 12hr old    1968 larva L3 puffstage 1-2    1495 larva L3 puffstage 3-6    1752 larva L3 puffstage 7-9    1668 white prepupae new    1595 white prepupae 12hr    1854 white prepupae 24hr    2229 pupae 2d postWPP    1512 pupae 3d postWPP    964 pupae 4d postWPP    1750 adult male 01day    1398 adult male 05day    1815 adult male 30day    1819 adult female 01day    3971 adult female 05day    4163 adult female 30day    4619 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (6780) embryo 02-04hr  (11796) embryo 04-06hr  (11349) embryo 06-08hr  (9375) embryo 08-10hr  (7291) embryo 10-12hr  (6505) embryo 12-14hr  (3097) embryo 14-16hr  (3958) embryo 16-18hr  (2468) embryo 18-20hr  (2193) embryo 20-22hr  (2536) embryo 22-24hr  (2166) larva L1  (2539) larva L2  (2141) larva L3 12hr old  (1968) larva L3 puffstage 1-2  (1495) larva L3 puffstage 3-6  (1752) larva L3 puffstage 7-9  (1668) white prepupae new  (1595) white prepupae 12hr  (1854) white prepupae 24hr  (2229) pupae 2d postWPP  (1512) pupae 3d postWPP  (964) pupae 4d postWPP  (1750) adult male 01day  (1398) adult male 05day  (1815) adult male 30day  (1819) adult female 01day  (3971) adult female 05day  (4163) adult female 30day  (4619) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (6780) embryo 02-04hr  (11796) embryo 04-06hr  (11349) embryo 06-08hr  (9375) embryo 08-10hr  (7291) embryo 10-12hr  (6505) embryo 12-14hr  (3097) embryo 14-16hr  (3958) embryo 16-18hr  (2468) embryo 18-20hr  (2193) embryo 20-22hr  (2536) embryo 22-24hr  (2166) larva L1  (2539) larva L2  (2141) larva L3 12hr old  (1968) larva L3 puffstage 1-2  1495 larva L3 puffstage 3-6  (1752) larva L3 puffstage 7-9  (1668) white prepupae new  (1595) white prepupae 12hr  (1854) white prepupae 24hr  (2229) pupae 2d postWPP  (1512) pupae 3d postWPP    964 pupae 4d postWPP  (1750) adult male 01day    1398 adult male 05day  (1815) adult male 30day  (1819) adult female 01day  (3971) adult female 05day  (4163) adult female 30day  (4619) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    6780 embryo 02-04hr  (11796) embryo 04-06hr  (11349) embryo 06-08hr    9375 embryo 08-10hr    7291 embryo 10-12hr    6505 embryo 12-14hr    3097 embryo 14-16hr    3958 embryo 16-18hr    2468 embryo 18-20hr    2193 embryo 20-22hr    2536 embryo 22-24hr    2166 larva L1    2539 larva L2    2141 larva L3 12hr old    1968 larva L3 puffstage 1-2    1495 larva L3 puffstage 3-6    1752 larva L3 puffstage 7-9    1668 white prepupae new    1595 white prepupae 12hr    1854 white prepupae 24hr    2229 pupae 2d postWPP    1512 pupae 3d postWPP    964 pupae 4d postWPP    1750 adult male 01day    1398 adult male 05day    1815 adult male 30day    1819 adult female 01day    3971 adult female 05day    4163 adult female 30day    4619 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    6780 embryo 02-04hr    11796 embryo 04-06hr    11349 embryo 06-08hr    9375 embryo 08-10hr    7291 embryo 10-12hr    6505 embryo 12-14hr    3097 embryo 14-16hr    3958 embryo 16-18hr    2468 embryo 18-20hr    2193 embryo 20-22hr    2536 embryo 22-24hr    2166 larva L1    2539 larva L2    2141 larva L3 12hr old    1968 larva L3 puffstage 1-2    1495 larva L3 puffstage 3-6    1752 larva L3 puffstage 7-9    1668 white prepupae new    1595 white prepupae 12hr    1854 white prepupae 24hr    2229 pupae 2d postWPP    1512 pupae 3d postWPP    964 pupae 4d postWPP    1750 adult male 01day    1398 adult male 05day    1815 adult male 30day    1819 adult female 01day    3971 adult female 05day    4163 adult female 30day    4619 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0038948 expression level Developmental Stage   Expression Level embryo 00-02hr    6780 embryo 02-04hr    11796 embryo 04-06hr    11349 embryo 06-08hr    9375 embryo 08-10hr    7291 embryo 10-12hr    6505 embryo 12-14hr    3097 embryo 14-16hr    3958 embryo 16-18hr    2468 embryo 18-20hr    2193 embryo 20-22hr    2536 embryo 22-24hr    2166 larva L1    2539 larva L2    2141 larva L3 12hr old    1968 larva L3 puffstage 1-2    1495 larva L3 puffstage 3-6    1752 larva L3 puffstage 7-9    1668 white prepupae new    1595 white prepupae 12hr    1854 white prepupae 24hr    2229 pupae 2d postWPP    1512 pupae 3d postWPP    964 pupae 4d postWPP    1750 adult male 01day    1398 adult male 05day    1815 adult male 30day    1819 adult female 01day    3971 adult female 05day    4163 adult female 30day    4619 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (6780) embryo 02-04hr  (11796) embryo 04-06hr  (11349) embryo 06-08hr  (9375) embryo 08-10hr  (7291) embryo 10-12hr  (6505) embryo 12-14hr  (3097) embryo 14-16hr  (3958) embryo 16-18hr  (2468) embryo 18-20hr  (2193) embryo 20-22hr  (2536) embryo 22-24hr  (2166) larva L1  (2539) larva L2  (2141) larva L3 12hr old  (1968) larva L3 puffstage 1-2  (1495) larva L3 puffstage 3-6  (1752) larva L3 puffstage 7-9  (1668) white prepupae new  (1595) white prepupae 12hr  (1854) white prepupae 24hr  (2229) pupae 2d postWPP  (1512) pupae 3d postWPP  (964) pupae 4d postWPP  (1750) adult male 01day  (1398) adult male 05day  (1815) adult male 30day  (1819) adult female 01day  (3971) adult female 05day  (4163) adult female 30day  (4619) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (6780) embryo 02-04hr  (11796) embryo 04-06hr  (11349) embryo 06-08hr  (9375) embryo 08-10hr  (7291) embryo 10-12hr  (6505) embryo 12-14hr  (3097) embryo 14-16hr  (3958) embryo 16-18hr  2468 embryo 18-20hr  2193 embryo 20-22hr  (2536) embryo 22-24hr  2166 larva L1  (2539) larva L2  2141 larva L3 12hr old  1968 larva L3 puffstage 1-2  1495 larva L3 puffstage 3-6  1752 larva L3 puffstage 7-9  1668 white prepupae new  1595 white prepupae 12hr  1854 white prepupae 24hr  2229 pupae 2d postWPP  1512 pupae 3d postWPP    964 pupae 4d postWPP  1750 adult male 01day    1398 adult male 05day  1815 adult male 30day  1819 adult female 01day  (3971) adult female 05day  (4163) adult female 30day  (4619) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    6780 embryo 02-04hr  11796 embryo 04-06hr  11349 embryo 06-08hr    9375 embryo 08-10hr    7291 embryo 10-12hr    6505 embryo 12-14hr    3097 embryo 14-16hr    3958 embryo 16-18hr    2468 embryo 18-20hr    2193 embryo 20-22hr    2536 embryo 22-24hr    2166 larva L1    2539 larva L2    2141 larva L3 12hr old    1968 larva L3 puffstage 1-2    1495 larva L3 puffstage 3-6    1752 larva L3 puffstage 7-9    1668 white prepupae new    1595 white prepupae 12hr    1854 white prepupae 24hr    2229 pupae 2d postWPP    1512 pupae 3d postWPP    964 pupae 4d postWPP    1750 adult male 01day    1398 adult male 05day    1815 adult male 30day    1819 adult female 01day    3971 adult female 05day    4163 adult female 30day    4619 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    6780 embryo 02-04hr    11796 embryo 04-06hr    11349 embryo 06-08hr    9375 embryo 08-10hr    7291 embryo 10-12hr    6505 embryo 12-14hr    3097 embryo 14-16hr    3958 embryo 16-18hr    2468 embryo 18-20hr    2193 embryo 20-22hr    2536 embryo 22-24hr    2166 larva L1    2539 larva L2    2141 larva L3 12hr old    1968 larva L3 puffstage 1-2    1495 larva L3 puffstage 3-6    1752 larva L3 puffstage 7-9    1668 white prepupae new    1595 white prepupae 12hr    1854 white prepupae 24hr    2229 pupae 2d postWPP    1512 pupae 3d postWPP    964 pupae 4d postWPP    1750 adult male 01day    1398 adult male 05day    1815 adult male 30day    1819 adult female 01day    3971 adult female 05day    4163 adult female 30day    4619 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0038948    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0038948 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, adult Malpighian tubules, larval salivary gland, larval trachea, adult ovary, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0038948 expression level Tissue   Expression Level Larval Central Nervous System    140.025 Larval Midgut    101.2 Larval Hindgut    146.2 Larval Malpighian Tubules    83.4 Larval Fat Body    68.6 Larval Salivary Gland    117.2 Larval Trachea    140.375 Larval Carcass    110 Adult Head    86.5 Adult Eye    77.6 Adult Brain    76.3 Adult Thoracic-Abdominal Ganglion    71.9 Adult Crop    129.4 Adult Midgut    118.2 Adult Hindgut    116.6 Adult Malpighian Tubules    153.5 Adult Fat Body    83.5 Adult Salivary Gland    93.8 Adult Heart    77.225 Adult VirginFemale Spermatheca    61.3 Adult InseminatedFemale Spermatheca    65.7 Adult Ovary    155.9 Adult Testis    63.1 Adult Male Accessory Gland    99.4 Adult Carcass    103.4 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    140.025 Larval Midgut    101.2 Larval Hindgut    146.2 Larval Malpighian Tubules    83.4 Larval Fat Body    68.6 Larval Salivary Gland    117.2 Larval Trachea    140.375 Larval Carcass    110 Adult Head    86.5 Adult Eye    77.6 Adult Brain    76.3 Adult Thoracic-Abdominal Ganglion    71.9 Adult Crop    129.4 Adult Midgut    118.2 Adult Hindgut    116.6 Adult Malpighian Tubules    153.5 Adult Fat Body    83.5 Adult Salivary Gland    93.8 Adult Heart    77.225 Adult VirginFemale Spermatheca    61.3 Adult InseminatedFemale Spermatheca    65.7 Adult Ovary    155.9 Adult Testis    63.1 Adult Male Accessory Gland    99.4 Adult Carcass    103.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    140.025 Larval Midgut    101.2 Larval Hindgut    146.2 Larval Malpighian Tubules    83.4 Larval Fat Body    68.6 Larval Salivary Gland    117.2 Larval Trachea    140.375 Larval Carcass    110 Adult Head    86.5 Adult Eye    77.6 Adult Brain    76.3 Adult Thoracic-Abdominal Ganglion    71.9 Adult Crop    129.4 Adult Midgut    118.2 Adult Hindgut    116.6 Adult Malpighian Tubules    153.5 Adult Fat Body    83.5 Adult Salivary Gland    93.8 Adult Heart    77.225 Adult VirginFemale Spermatheca    61.3 Adult InseminatedFemale Spermatheca    65.7 Adult Ovary    155.9 Adult Testis    63.1 Adult Male Accessory Gland    99.4 Adult Carcass    103.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    140.025 Larval Midgut    101.2 Larval Hindgut    146.2 Larval Malpighian Tubules    83.4 Larval Fat Body    68.6 Larval Salivary Gland    117.2 Larval Trachea    140.375 Larval Carcass    110 Adult Head    86.5 Adult Eye    77.6 Adult Brain    76.3 Adult Thoracic-Abdominal Ganglion    71.9 Adult Crop    129.4 Adult Midgut    118.2 Adult Hindgut    116.6 Adult Malpighian Tubules    153.5 Adult Fat Body    83.5 Adult Salivary Gland    93.8 Adult Heart    77.225 Adult VirginFemale Spermatheca    61.3 Adult InseminatedFemale Spermatheca    65.7 Adult Ovary    155.9 Adult Testis    63.1 Adult Male Accessory Gland    99.4 Adult Carcass    103.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0038948 expression level Tissue   Expression Level Larval Central Nervous System    140.025 Larval Midgut    101.2 Larval Hindgut    146.2 Larval Malpighian Tubules    83.4 Larval Fat Body    68.6 Larval Salivary Gland    117.2 Larval Trachea    140.375 Larval Carcass    110 Adult Head    86.5 Adult Eye    77.6 Adult Brain    76.3 Adult Thoracic-Abdominal Ganglion    71.9 Adult Crop    129.4 Adult Midgut    118.2 Adult Hindgut    116.6 Adult Malpighian Tubules    153.5 Adult Fat Body    83.5 Adult Salivary Gland    93.8 Adult Heart    77.225 Adult VirginFemale Spermatheca    61.3 Adult InseminatedFemale Spermatheca    65.7 Adult Ovary    155.9 Adult Testis    63.1 Adult Male Accessory Gland    99.4 Adult Carcass    103.4 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    140.025 Larval Midgut    101.2 Larval Hindgut    146.2 Larval Malpighian Tubules    83.4 Larval Fat Body    68.6 Larval Salivary Gland    117.2 Larval Trachea    140.375 Larval Carcass    110 Adult Head    86.5 Adult Eye    77.6 Adult Brain    76.3 Adult Thoracic-Abdominal Ganglion    71.9 Adult Crop    129.4 Adult Midgut    118.2 Adult Hindgut    116.6 Adult Malpighian Tubules    153.5 Adult Fat Body    83.5 Adult Salivary Gland    93.8 Adult Heart    77.225 Adult VirginFemale Spermatheca    61.3 Adult InseminatedFemale Spermatheca    65.7 Adult Ovary    155.9 Adult Testis    63.1 Adult Male Accessory Gland    99.4 Adult Carcass    103.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    140.025 Larval Midgut    101.2 Larval Hindgut    146.2 Larval Malpighian Tubules    83.4 Larval Fat Body    68.6 Larval Salivary Gland    117.2 Larval Trachea    140.375 Larval Carcass    110 Adult Head    86.5 Adult Eye    77.6 Adult Brain    76.3 Adult Thoracic-Abdominal Ganglion    71.9 Adult Crop    129.4 Adult Midgut    118.2 Adult Hindgut    116.6 Adult Malpighian Tubules    153.5 Adult Fat Body    83.5 Adult Salivary Gland    93.8 Adult Heart    77.225 Adult VirginFemale Spermatheca    61.3 Adult InseminatedFemale Spermatheca    65.7 Adult Ovary    155.9 Adult Testis    63.1 Adult Male Accessory Gland    99.4 Adult Carcass    103.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    140.025 Larval Midgut    101.2 Larval Hindgut    146.2 Larval Malpighian Tubules    83.4 Larval Fat Body    68.6 Larval Salivary Gland    117.2 Larval Trachea    140.375 Larval Carcass    110 Adult Head    86.5 Adult Eye    77.6 Adult Brain    76.3 Adult Thoracic-Abdominal Ganglion    71.9 Adult Crop    129.4 Adult Midgut    118.2 Adult Hindgut    116.6 Adult Malpighian Tubules    153.5 Adult Fat Body    83.5 Adult Salivary Gland    93.8 Adult Heart    77.225 Adult VirginFemale Spermatheca    61.3 Adult InseminatedFemale Spermatheca    65.7 Adult Ovary    155.9 Adult Testis    63.1 Adult Male Accessory Gland    99.4 Adult Carcass    103.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    86.5   NA  Eye    77.6   NA  Brain    76.3   140.025  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    71.9   NA  Crop    129.4   101.2  Midgut    118.2   146.2  Hindgut    116.6   83.4  Malpighian Tubules    153.5   68.6  Fat Body    83.5   117.2  Salivary Gland    93.8   NA  Heart    77.225   140.375  Trachea    NA   NA  VirginFemale Spermatheca    61.3   NA  InseminatedFemale Spermatheca    65.7   NA  Ovary    155.9   NA  Testis    63.1   NA  Male Accessory Gland    99.4   110  Carcass    103.4 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_08
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038948 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5383-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable PSRFM1 viable, with Scer\GAL4pnr-MD237 PSRGD11631 Sterility Allele fertile PSRFM1 Other Phenotypes Allele visible, with Scer\GAL4ap-md544 PSRScer\UAS.cKa visible, with Scer\GAL4pnr-MD237 PSRGD11631 visible | male, with Scer\GAL4Act5C.PU PSRScer\UAS.cKa visible | male, with Scer\GAL4tub.PU PSRScer\UAS.cKa Phenotype manifest in Allele eye disc, with Scer\GAL4GMR.PF PSRScer\UAS.cKa male genitalia, with Scer\GAL4Act5C.PU PSRScer\UAS.cKa male genitalia, with Scer\GAL4tub.PU PSRScer\UAS.cKa ommatidium PSRFM1 trichogen cell, with Scer\GAL4pnr-MD237 PSRGD11631 wing, with Scer\GAL4ap-md544 PSRScer\UAS.cKa
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of PSR Class Mutagen Stocks Known lesion PSREY07193 1 -- PSRFM1 Delta2-3 0 Yes PSRnull 0 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of PSR Class Mutagen Stocks Known lesion PSRGD11631 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes PSRHMS00576 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes PSRScer\UAS.cKa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6190 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD11631} NA P{TRiP.HMS00576} NA P{UAS-PSR.K} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}EP561 NA P{EPgy2}PSREY07193 NA miscellaneous insertions P{?EP}PSRFM1 NA
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
	There is no information supporting a molecular function term for this gene. (Based on a review of available data before: 2006)
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
cell competition in a multicellular organism inferred from mutant phenotype (Li and Baker, 2007) negative regulation of apoptosis inferred from genetic interaction with W (Krieser et al., 2007) inferred from mutant phenotype (Krieser et al., 2007) negative regulation of JNK cascade inferred from genetic interaction with puc (Krieser et al., 2007)
Cellular Component
CV term Evidence References
nucleus inferred from direct assay (Krieser et al., 2007)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
nucleus inferred from sequence or structural similarity with UniProtKB:Q6NYC1 (assigned by UniProtKB) (FBrf0198864)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions PSR allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 67574 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0038948 DroID - A comprehensive database of gene and protein interactions. • FBgn0038948 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42616
Orthologs
Genome-wide drosophilid orthologs	Dana\GF16939 Dere\GG12525 Dgri\GH19722 Dmoj\GI22281 Dper\GL24169 Dpse\GA18839 Dsec\GM23660 Dsim\GD18469 Dvir\GJ24074 Dwil\GK14253 Dyak\GE24049
Curated drosophilid orthologs	Dpse\GA18839
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL008084-PA Aedes aegypti (mosquito) AGAP000158-PA Anopheles gambiae (mosquito) XP_394543.2 Apis mellifera (honey bee) XP_001943315.1 Acyrthosiphon pisum (pea aphid) At5g06550.1 Arabidopsis thaliana (wall cress) 26004 Batrachochytrium dendrobatidis (chytrid fungus) 119552 Branchiostoma floridae (lancelet) 119559 Branchiostoma floridae (lancelet) BGIBMGA005792-PA Bombyx mori (silk worm) ENSBTAP00000025492 Bos taurus (bovine) CN03911 Caenorhabditis brenneri (small nematode) CN15625 Caenorhabditis brenneri (small nematode) CBP20972 Caenorhabditis briggsae (nematode) CE27146 Caenorhabditis elegans (worm) ENSCAFP00000007665 Canis familiaris (dog) ENSCINP00000014659 Ciona intestinalis (sea squirt) JA05521 Caenorhabditis japonica (nematode) CPIJ019866 Culex pipens (mosquito) ENSCPOP00000003815 Cavia porcellus (guinea pig) 120259 Chlamidomonas reinhardtii (green alga) RP35202 Caenorhabditis remanei (nematode) ENSCSAVP00000016921 Ciona savignyi (sedentary tunicate) 149082 Capitella spl (polychaete worm) DDB0238369 Dictyostelium discoideum (amoeba) 216924 Daphnia pulex (daphnia) ENSDARP00000022328 Danio rerio (zebra fish) ENSECAP00000018718 Equus caballus (horse) ENSGACP00000019814 Gymnopilus aculeatus (mushroom) ENSGALP00000002781 Gallus gallus (chicken) 192952 Hypsipyla robusta (cedar shoot borer) ENSP00000302916 Homo sapiens (human) ISCW020652-PA Ixodes scapularis (deer tick) 117140 Lottia gigantea (owl limpet) 1474 Monocosta brevicollis (choanoflagellate) ENSMODP00000032067 Monodelphis domestica (gray opossum) ENSMMUP00000029497 Macaca mulatta (rhesus monkey) ENSMUSP00000047570 Mus musculus (house mouse) 185932 Nematostella vectensis (starlet anemone) XP_001601114.1 Nasonia vitripennis (wasp) ENSOANP00000018329 Ornithorynchus anatinus (platypus) ENSORLP00000023114 Oryzias latipes (japanese killifish) 16032 Ostreococcus tauri (green alga) PHUM010147-PA Pediculus humanus (human body louse) PP06829 Pristionchus pacificus (nematode) ENSPPYP00000007838 Pongo pygmaeus (orangutan) 41695 Phytophthora ramorum (sudden oak death pathogen) 119111 Phytophthora sojae (root rot pathogen) ENSPTRP00000016473 Pan troglodytes (chimpanzee) ENSRNOP00000040900 Rattus norvegicus (norway rat) XP_001195394.1 Strongylocentrotus purpuratus (purple sea urchin) 49617 Trichoplax adhaerens (metazoa) XP_966727.1 Tribolium castaneum (red flour beetle) ENSTNIP00000009269 Tetraodon nigroviridis (green spotted pufferfish) 14890 Thalassiosira pseudonana (marine diatom) ENSTRUP00000002033 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000042228 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB12153 NV11308 LH12569 ISCW020652 FBgn0241188 FBgn0216259 FBgn0211159 FBgn0189992 FBgn0178525 JGI_V11_216924 FBgn0078839 FBgn0161759 FBgn0145009 FBgn0127186 FBgn0104813 FBgn0093958 CPIJ019866 BGIBMGA005792 ACYPI009937 GB15204 AGAP000158 AAEL013632 AAEL008084 PHUM477580 GLEAN_14173
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	16798 y1 w67c23; P{EPgy2}PSREY07193 33700 y1 sc* v1; P{TRiP.HMS00576}attP2
VDRC	v22689 w1118; P{GD11631}v22689 v22108 w1118; P{GD11631}v22108/TM3
Genomic Clones ( 1 )
	BACR09L14 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 42 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD25827
Other clones	DPiM_LD25827
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT01782 AT04631 AT31763 GH15904 GM01430 GM05463 GM05481 GM31853 LD05310 LD06051 LD07676 LD09902 LD21195 LD22859 LD23302 LD25607 LD27115 LD28790 LD31306 LD33615 LD36263 LD38244 RE21382 RE28722 RE29918 RE39458 RE62009 RH54228 SD03334 SD03667 SD24483
Other clones	31990 73834 78053 160235 EK142563 EK196406 EK211715 EP08405 FGM213G03
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0038948 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42616
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: PSR CG5383 (Krieser, 2004.3.4)
Source for database merge of	Source for merge of: PSR BEST:LD22859 (Rana, 2004.7.8)
Additional comments
Other Comments
	PSR is needed in wild-type cells for the death of Minute neighbours in cell competition experiments. (Li and Baker, 2007) Identification: in a screen for genes required for the phagocytosis of apoptotic cells in the Drosophila embryo using a panel of Drosophila strains carrying genomic deletions. Several candidate deletions were identified that displayed potential defects in this process. One of these was a large deletion that included the Drosophila homolog of the phosphatidylserine receptor (dPSR). (Krieser et al., 2004) May function to protect from death in Drosophila. (Krieser et al., 2004)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_142769 RefSeq (Proteins) • NP_651026 DDBJ / EMBL / GenBank • AA940716 AA941604 AAF55975 AAK93151 AW942817 AY051727 Entrez Gene - A searchable database of RefSeq genes. • 42616 UniProtKB/TrEMBL • Q9VD28
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Transcription factor jumonji/aspartyl beta-hydroxylase (IPR003347) Transcription factor jumonji (IPR013129)
Linkouts
	BioGRID - A database of protein and genetic interactions • 67574 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0038948 DroID - A comprehensive database of gene and protein interactions. • FBgn0038948 DRSC - Results from RNAi screens. • FBgn0038948 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038948 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5383-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0038948 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42616 InParanoid A subset of ortholog calls from InParanoid. • AAEL008084-PA Aedes aegypti (mosquito) AGAP000158-PA Anopheles gambiae (mosquito) XP_394543.2 Apis mellifera (honey bee) XP_001943315.1 Acyrthosiphon pisum (pea aphid) At5g06550.1 Arabidopsis thaliana (wall cress) 26004 Batrachochytrium dendrobatidis (chytrid fungus) 119552 Branchiostoma floridae (lancelet) 119559 Branchiostoma floridae (lancelet) BGIBMGA005792-PA Bombyx mori (silk worm) ENSBTAP00000025492 Bos taurus (bovine) CN03911 Caenorhabditis brenneri (small nematode) CN15625 Caenorhabditis brenneri (small nematode) CBP20972 Caenorhabditis briggsae (nematode) CE27146 Caenorhabditis elegans (worm) ENSCAFP00000007665 Canis familiaris (dog) ENSCINP00000014659 Ciona intestinalis (sea squirt) JA05521 Caenorhabditis japonica (nematode) CPIJ019866 Culex pipens (mosquito) ENSCPOP00000003815 Cavia porcellus (guinea pig) 120259 Chlamidomonas reinhardtii (green alga) RP35202 Caenorhabditis remanei (nematode) ENSCSAVP00000016921 Ciona savignyi (sedentary tunicate) 149082 Capitella spl (polychaete worm) DDB0238369 Dictyostelium discoideum (amoeba) 216924 Daphnia pulex (daphnia) ENSDARP00000022328 Danio rerio (zebra fish) ENSECAP00000018718 Equus caballus (horse) ENSGACP00000019814 Gymnopilus aculeatus (mushroom) ENSGALP00000002781 Gallus gallus (chicken) 192952 Hypsipyla robusta (cedar shoot borer) ENSP00000302916 Homo sapiens (human) ISCW020652-PA Ixodes scapularis (deer tick) 117140 Lottia gigantea (owl limpet) 1474 Monocosta brevicollis (choanoflagellate) ENSMODP00000032067 Monodelphis domestica (gray opossum) ENSMMUP00000029497 Macaca mulatta (rhesus monkey) ENSMUSP00000047570 Mus musculus (house mouse) 185932 Nematostella vectensis (starlet anemone) XP_001601114.1 Nasonia vitripennis (wasp) ENSOANP00000018329 Ornithorynchus anatinus (platypus) ENSORLP00000023114 Oryzias latipes (japanese killifish) 16032 Ostreococcus tauri (green alga) PHUM010147-PA Pediculus humanus (human body louse) PP06829 Pristionchus pacificus (nematode) ENSPPYP00000007838 Pongo pygmaeus (orangutan) 41695 Phytophthora ramorum (sudden oak death pathogen) 119111 Phytophthora sojae (root rot pathogen) ENSPTRP00000016473 Pan troglodytes (chimpanzee) ENSRNOP00000040900 Rattus norvegicus (norway rat) XP_001195394.1 Strongylocentrotus purpuratus (purple sea urchin) 49617 Trichoplax adhaerens (metazoa) XP_966727.1 Tribolium castaneum (red flour beetle) ENSTNIP00000009269 Tetraodon nigroviridis (green spotted pufferfish) 14890 Thalassiosira pseudonana (marine diatom) ENSTRUP00000002033 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000042228 Xenopus tropicalis (frog) Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /genebrief/phosph_ser_rec.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42616 modMine - Data generated by the modENCODE project. • FBgn0038948 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB12153 NV11308 LH12569 ISCW020652 FBgn0241188 FBgn0216259 FBgn0211159 FBgn0189992 FBgn0178525 JGI_V11_216924 FBgn0078839 FBgn0161759 FBgn0145009 FBgn0127186 FBgn0104813 FBgn0093958 CPIJ019866 BGIBMGA005792 ACYPI009937 GB15204 AGAP000158 AAEL013632 AAEL008084 PHUM477580 GLEAN_14173
Synonyms & Secondary IDs ( 10 )
Reported As
Symbol Synonym	BEST:LD22859   CG5383 (Rana, 2004.7.8, Klose et al., 2006, Curtis et al., 2011, Krieser et al., 2007, Ni et al., 2010.12.1) dPSR (Krieser et al., 2005, Krieser et al., 2004, Krieser et al., 2007, Krieser et al., 2007) L0022859 (Fadok et al., 2000) PS (Bangs et al., 2000) PSR (FBrf0198864, Curtis et al., 2011) psr (Li and Baker, 2007, Li and Baker, 2007) Psr (Andersen et al., 2010)
Name Synonym	phosphatidylserine receptor (Krieser et al., 2004, Li and Baker, 2007) phosphatidyl-serine receptor (Li and Baker, 2007)
Secondary FlyBase IDs
	FBgn0042088
References ( 24 )
Generate a list of	All references relating to this gene ( 24 )
List References by type	Research paper  ( 6 ) Supplementary material  ( 3 ) Review  ( 2 ) Personal communication to FlyBase  ( 5 ) Abstract  ( 3 ) FlyBase analysis  ( 2 ) Protein sequence record  ( 1 ) Computer file  ( 1 )
Recent research papers ( 2 )
	Curtis et al., 2011, Dev. Biol. 350(2): 534--547 Histone lysine demethylases function as co-repressors of SWI/SNF remodeling activities during Drosophila wing development. [FBrf0212876] Andersen et al., 2010, Mol. Cell. Biol. 30(19): 4744--4755 Drosophila MCRS2 Associates with RNA Polymerase II Complexes To Regulate Transcription. [FBrf0211794] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...