General Information Symbol Dmel\ PSRSpecies D. melanogaster Name phosphatidylserine receptor Annotation symbol CG5383 Feature type protein_coding_gene FlyBase ID FBgn0038948 Gene Model Status Current Stock availability 4 publicly
available Also Known As dPSR Genomic Location Chromosome (arm) 3R Recombination map Cytogenetic map 94A6-94A6 Sequence location 3R:18,186,504..18,188,093 [-]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information The gene
phosphatidylserine receptor is referred to in FlyBase by the symbol
Dmel\PSR (CG5383, FBgn0038948). It is a protein_coding_gene from
Drosophila melanogaster . Its
molecular function is unknown. There is experimental evidence that it is involved in the
biological process : negative regulation of apoptotic process; cell competition in a multicellular organism; negative regulation of JNK cascade.
7 alleles are reported . The
phenotypes of these alleles are annotated with: eye disc; trichogen cell; male genitalia; wing; ommatidium. It has
2 annotated transcripts and
2 annotated polypeptides .
Protein features are: JmjC domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, adult Malpighian tubules, larval salivary gland, larval trachea, adult ovary, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1640943_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of PSR. Gene sequence location is
3R:18186504..18188093 .
User Contributed Data External Summaries
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FB2013_03
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.43
gene_with_stop_codon_read_through ; SO:0000697
Stop-codon suppression (UGA) postulated; FBrf0216884.
Gene model reviewed during 5.44
Gene model reviewed during 5.49
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript Expression
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) inferred from direct assay
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
140.025
Larval Midgut
101.2
Larval Hindgut
146.2
Larval Malpighian Tubules
83.4
Larval Fat Body
68.6
Larval Salivary Gland
117.2
Larval Trachea
140.375
Larval Carcass
110
Adult Head
86.5
Adult Eye
77.6
Adult Brain
76.3
Adult Thoracic-Abdominal Ganglion
71.9
Adult Crop
129.4
Adult Midgut
118.2
Adult Hindgut
116.6
Adult Malpighian Tubules
153.5
Adult Fat Body
83.5
Adult Salivary Gland
93.8
Adult Heart
77.225
Adult VirginFemale Spermatheca
61.3
Adult InseminatedFemale Spermatheca
65.7
Adult Ovary
155.9
Adult Testis
63.1
Adult Male Accessory Gland
99.4
Adult Carcass
103.4
Expression Level Scale
None
Low
Moderate
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
140.025
Larval Midgut
101.2
Larval Hindgut
146.2
Larval Malpighian Tubules
83.4
Larval Fat Body
68.6
Larval Salivary Gland
117.2
Larval Trachea
140.375
Larval Carcass
110
Adult Head
86.5
Adult Eye
77.6
Adult Brain
76.3
Adult Thoracic-Abdominal Ganglion
71.9
Adult Crop
129.4
Adult Midgut
118.2
Adult Hindgut
116.6
Adult Malpighian Tubules
153.5
Adult Fat Body
83.5
Adult Salivary Gland
93.8
Adult Heart
77.225
Adult VirginFemale Spermatheca
61.3
Adult InseminatedFemale Spermatheca
65.7
Adult Ovary
155.9
Adult Testis
63.1
Adult Male Accessory Gland
99.4
Adult Carcass
103.4
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
140.025
Larval Midgut
101.2
Larval Hindgut
146.2
Larval Malpighian Tubules
83.4
Larval Fat Body
68.6
Larval Salivary Gland
117.2
Larval Trachea
140.375
Larval Carcass
110
Adult Head
86.5
Adult Eye
77.6
Adult Brain
76.3
Adult Thoracic-Abdominal Ganglion
71.9
Adult Crop
129.4
Adult Midgut
118.2
Adult Hindgut
116.6
Adult Malpighian Tubules
153.5
Adult Fat Body
83.5
Adult Salivary Gland
93.8
Adult Heart
77.225
Adult VirginFemale Spermatheca
61.3
Adult InseminatedFemale Spermatheca
65.7
Adult Ovary
155.9
Adult Testis
63.1
Adult Male Accessory Gland
99.4
Adult Carcass
103.4
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
140.025
Larval Midgut
101.2
Larval Hindgut
146.2
Larval Malpighian Tubules
83.4
Larval Fat Body
68.6
Larval Salivary Gland
117.2
Larval Trachea
140.375
Larval Carcass
110
Adult Head
86.5
Adult Eye
77.6
Adult Brain
76.3
Adult Thoracic-Abdominal Ganglion
71.9
Adult Crop
129.4
Adult Midgut
118.2
Adult Hindgut
116.6
Adult Malpighian Tubules
153.5
Adult Fat Body
83.5
Adult Salivary Gland
93.8
Adult Heart
77.225
Adult VirginFemale Spermatheca
61.3
Adult InseminatedFemale Spermatheca
65.7
Adult Ovary
155.9
Adult Testis
63.1
Adult Male Accessory Gland
99.4
Adult Carcass
103.4
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
140.025
Larval Midgut
101.2
Larval Hindgut
146.2
Larval Malpighian Tubules
83.4
Larval Fat Body
68.6
Larval Salivary Gland
117.2
Larval Trachea
140.375
Larval Carcass
110
Adult Head
86.5
Adult Eye
77.6
Adult Brain
76.3
Adult Thoracic-Abdominal Ganglion
71.9
Adult Crop
129.4
Adult Midgut
118.2
Adult Hindgut
116.6
Adult Malpighian Tubules
153.5
Adult Fat Body
83.5
Adult Salivary Gland
93.8
Adult Heart
77.225
Adult VirginFemale Spermatheca
61.3
Adult InseminatedFemale Spermatheca
65.7
Adult Ovary
155.9
Adult Testis
63.1
Adult Male Accessory Gland
99.4
Adult Carcass
103.4
Expression Level Scale
None
Low
Moderate
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
140.025
Larval Midgut
101.2
Larval Hindgut
146.2
Larval Malpighian Tubules
83.4
Larval Fat Body
68.6
Larval Salivary Gland
117.2
Larval Trachea
140.375
Larval Carcass
110
Adult Head
86.5
Adult Eye
77.6
Adult Brain
76.3
Adult Thoracic-Abdominal Ganglion
71.9
Adult Crop
129.4
Adult Midgut
118.2
Adult Hindgut
116.6
Adult Malpighian Tubules
153.5
Adult Fat Body
83.5
Adult Salivary Gland
93.8
Adult Heart
77.225
Adult VirginFemale Spermatheca
61.3
Adult InseminatedFemale Spermatheca
65.7
Adult Ovary
155.9
Adult Testis
63.1
Adult Male Accessory Gland
99.4
Adult Carcass
103.4
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
140.025
Larval Midgut
101.2
Larval Hindgut
146.2
Larval Malpighian Tubules
83.4
Larval Fat Body
68.6
Larval Salivary Gland
117.2
Larval Trachea
140.375
Larval Carcass
110
Adult Head
86.5
Adult Eye
77.6
Adult Brain
76.3
Adult Thoracic-Abdominal Ganglion
71.9
Adult Crop
129.4
Adult Midgut
118.2
Adult Hindgut
116.6
Adult Malpighian Tubules
153.5
Adult Fat Body
83.5
Adult Salivary Gland
93.8
Adult Heart
77.225
Adult VirginFemale Spermatheca
61.3
Adult InseminatedFemale Spermatheca
65.7
Adult Ovary
155.9
Adult Testis
63.1
Adult Male Accessory Gland
99.4
Adult Carcass
103.4
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
140.025
Larval Midgut
101.2
Larval Hindgut
146.2
Larval Malpighian Tubules
83.4
Larval Fat Body
68.6
Larval Salivary Gland
117.2
Larval Trachea
140.375
Larval Carcass
110
Adult Head
86.5
Adult Eye
77.6
Adult Brain
76.3
Adult Thoracic-Abdominal Ganglion
71.9
Adult Crop
129.4
Adult Midgut
118.2
Adult Hindgut
116.6
Adult Malpighian Tubules
153.5
Adult Fat Body
83.5
Adult Salivary Gland
93.8
Adult Heart
77.225
Adult VirginFemale Spermatheca
61.3
Adult InseminatedFemale Spermatheca
65.7
Adult Ovary
155.9
Adult Testis
63.1
Adult Male Accessory Gland
99.4
Adult Carcass
103.4
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
86.5
NA
Eye
77.6
NA
Brain
76.3
140.025
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
71.9
NA
Crop
129.4
101.2
Midgut
118.2
146.2
Hindgut
116.6
83.4
Malpighian Tubules
153.5
68.6
Fat Body
83.5
117.2
Salivary Gland
93.8
NA
Heart
77.225
140.375
Trachea
NA
NA
VirginFemale Spermatheca
61.3
NA
InseminatedFemale Spermatheca
65.7
NA
Ovary
155.9
NA
Testis
63.1
NA
Male Accessory Gland
99.4
110
Carcass
103.4
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
37
central nervous system, larvae L3
23
central nervous system, pupae P8
8
head, virgin 1-day female
6
head, virgin 4-day female
8
head, virgin 20-day female
10
head, mated 1-day female
7
head, mated 4-day female
6
head, mated 20-day female
8
head, mated 1-day male
8
head, mated 4-day male
8
head, mated 20-day male
11
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
3
digestive system, larvae L3 wandering
12
digestive system, 1-day adult
12
digestive system, 4-day adult
13
digestive system, 20-day adult
17
fat body, larvae L3 wandering
5
fat body, white prepupae
8
fat body, pupae P8
19
carcass, larvae L3 wandering
18
carcass, 1-day adult
8
carcass, 4-day adult
9
carcass, 20-day adult
11
ovary, virgin 4-day female
51
ovary, mated 4-day female
38
testis, mated 4-day male
32
accessory gland, mated 4-day male
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(37)
central nervous system, larvae L3
23
central nervous system, pupae P8
8
head, virgin 1-day female
6
head, virgin 4-day female
8
head, virgin 20-day female
10
head, mated 1-day female
7
head, mated 4-day female
6
head, mated 20-day female
8
head, mated 1-day male
8
head, mated 4-day male
8
head, mated 20-day male
11
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
3
digestive system, larvae L3 wandering
12
digestive system, 1-day adult
12
digestive system, 4-day adult
13
digestive system, 20-day adult
17
fat body, larvae L3 wandering
5
fat body, white prepupae
8
fat body, pupae P8
19
carcass, larvae L3 wandering
18
carcass, 1-day adult
8
carcass, 4-day adult
9
carcass, 20-day adult
11
ovary, virgin 4-day female
(51)
ovary, mated 4-day female
(38)
testis, mated 4-day male
(32)
accessory gland, mated 4-day male
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
37
central nervous system, larvae L3
23
central nervous system, pupae P8
8
head, virgin 1-day female
6
head, virgin 4-day female
8
head, virgin 20-day female
10
head, mated 1-day female
7
head, mated 4-day female
6
head, mated 20-day female
8
head, mated 1-day male
8
head, mated 4-day male
8
head, mated 20-day male
11
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
3
digestive system, larvae L3 wandering
12
digestive system, 1-day adult
12
digestive system, 4-day adult
13
digestive system, 20-day adult
17
fat body, larvae L3 wandering
5
fat body, white prepupae
8
fat body, pupae P8
19
carcass, larvae L3 wandering
18
carcass, 1-day adult
8
carcass, 4-day adult
9
carcass, 20-day adult
11
ovary, virgin 4-day female
51
ovary, mated 4-day female
38
testis, mated 4-day male
32
accessory gland, mated 4-day male
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
37
central nervous system, larvae L3
23
central nervous system, pupae P8
8
head, virgin 1-day female
6
head, virgin 4-day female
8
head, virgin 20-day female
10
head, mated 1-day female
7
head, mated 4-day female
6
head, mated 20-day female
8
head, mated 1-day male
8
head, mated 4-day male
8
head, mated 20-day male
11
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
3
digestive system, larvae L3 wandering
12
digestive system, 1-day adult
12
digestive system, 4-day adult
13
digestive system, 20-day adult
17
fat body, larvae L3 wandering
5
fat body, white prepupae
8
fat body, pupae P8
19
carcass, larvae L3 wandering
18
carcass, 1-day adult
8
carcass, 4-day adult
9
carcass, 20-day adult
11
ovary, virgin 4-day female
51
ovary, mated 4-day female
38
testis, mated 4-day male
32
accessory gland, mated 4-day male
10
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
37
central nervous system, larvae L3
23
central nervous system, pupae P8
8
head, virgin 1-day female
6
head, virgin 4-day female
8
head, virgin 20-day female
10
head, mated 1-day female
7
head, mated 4-day female
6
head, mated 20-day female
8
head, mated 1-day male
8
head, mated 4-day male
8
head, mated 20-day male
11
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
3
digestive system, larvae L3 wandering
12
digestive system, 1-day adult
12
digestive system, 4-day adult
13
digestive system, 20-day adult
17
fat body, larvae L3 wandering
5
fat body, white prepupae
8
fat body, pupae P8
19
carcass, larvae L3 wandering
18
carcass, 1-day adult
8
carcass, 4-day adult
9
carcass, 20-day adult
11
ovary, virgin 4-day female
51
ovary, mated 4-day female
38
testis, mated 4-day male
32
accessory gland, mated 4-day male
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(37)
central nervous system, larvae L3
23
central nervous system, pupae P8
8
head, virgin 1-day female
6
head, virgin 4-day female
8
head, virgin 20-day female
10
head, mated 1-day female
7
head, mated 4-day female
6
head, mated 20-day female
8
head, mated 1-day male
8
head, mated 4-day male
8
head, mated 20-day male
11
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
3
digestive system, larvae L3 wandering
12
digestive system, 1-day adult
12
digestive system, 4-day adult
13
digestive system, 20-day adult
17
fat body, larvae L3 wandering
5
fat body, white prepupae
8
fat body, pupae P8
19
carcass, larvae L3 wandering
18
carcass, 1-day adult
8
carcass, 4-day adult
9
carcass, 20-day adult
11
ovary, virgin 4-day female
(51)
ovary, mated 4-day female
(38)
testis, mated 4-day male
32
accessory gland, mated 4-day male
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
37
central nervous system, larvae L3
23
central nervous system, pupae P8
8
head, virgin 1-day female
6
head, virgin 4-day female
8
head, virgin 20-day female
10
head, mated 1-day female
7
head, mated 4-day female
6
head, mated 20-day female
8
head, mated 1-day male
8
head, mated 4-day male
8
head, mated 20-day male
11
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
3
digestive system, larvae L3 wandering
12
digestive system, 1-day adult
12
digestive system, 4-day adult
13
digestive system, 20-day adult
17
fat body, larvae L3 wandering
5
fat body, white prepupae
8
fat body, pupae P8
19
carcass, larvae L3 wandering
18
carcass, 1-day adult
8
carcass, 4-day adult
9
carcass, 20-day adult
11
ovary, virgin 4-day female
51
ovary, mated 4-day female
38
testis, mated 4-day male
32
accessory gland, mated 4-day male
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
37
central nervous system, larvae L3
23
central nervous system, pupae P8
8
head, virgin 1-day female
6
head, virgin 4-day female
8
head, virgin 20-day female
10
head, mated 1-day female
7
head, mated 4-day female
6
head, mated 20-day female
8
head, mated 1-day male
8
head, mated 4-day male
8
head, mated 20-day male
11
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
3
digestive system, larvae L3 wandering
12
digestive system, 1-day adult
12
digestive system, 4-day adult
13
digestive system, 20-day adult
17
fat body, larvae L3 wandering
5
fat body, white prepupae
8
fat body, pupae P8
19
carcass, larvae L3 wandering
18
carcass, 1-day adult
8
carcass, 4-day adult
9
carcass, 20-day adult
11
ovary, virgin 4-day female
51
ovary, mated 4-day female
38
testis, mated 4-day male
32
accessory gland, mated 4-day male
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
99
embryo 02-04hr
172
embryo 04-06hr
165
embryo 06-08hr
136
embryo 08-10hr
106
embryo 10-12hr
94
embryo 12-14hr
45
embryo 14-16hr
58
embryo 16-18hr
36
embryo 18-20hr
32
embryo 20-22hr
37
embryo 22-24hr
31
larva L1
37
larva L2
31
larva L3 12hr old
29
larva L3 puffstage 1-2
22
larva L3 puffstage 3-6
25
larva L3 puffstage 7-9
24
white prepupae new
23
white prepupae 12hr
27
white prepupae 24hr
32
pupae 2d postWPP
22
pupae 3d postWPP
14
pupae 4d postWPP
25
adult male 01day
20
adult male 05day
26
adult male 30day
26
adult female 01day
58
adult female 05day
61
adult female 30day
67
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(99)
embryo 02-04hr
(172)
embryo 04-06hr
(165)
embryo 06-08hr
(136)
embryo 08-10hr
(106)
embryo 10-12hr
(94)
embryo 12-14hr
(45)
embryo 14-16hr
(58)
embryo 16-18hr
(36)
embryo 18-20hr
(32)
embryo 20-22hr
(37)
embryo 22-24hr
(31)
larva L1
(37)
larva L2
(31)
larva L3 12hr old
(29)
larva L3 puffstage 1-2
22
larva L3 puffstage 3-6
25
larva L3 puffstage 7-9
24
white prepupae new
23
white prepupae 12hr
(27)
white prepupae 24hr
(32)
pupae 2d postWPP
22
pupae 3d postWPP
14
pupae 4d postWPP
25
adult male 01day
20
adult male 05day
26
adult male 30day
26
adult female 01day
(58)
adult female 05day
(61)
adult female 30day
(67)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
99
embryo 02-04hr
(172)
embryo 04-06hr
(165)
embryo 06-08hr
(136)
embryo 08-10hr
106
embryo 10-12hr
94
embryo 12-14hr
45
embryo 14-16hr
58
embryo 16-18hr
36
embryo 18-20hr
32
embryo 20-22hr
37
embryo 22-24hr
31
larva L1
37
larva L2
31
larva L3 12hr old
29
larva L3 puffstage 1-2
22
larva L3 puffstage 3-6
25
larva L3 puffstage 7-9
24
white prepupae new
23
white prepupae 12hr
27
white prepupae 24hr
32
pupae 2d postWPP
22
pupae 3d postWPP
14
pupae 4d postWPP
25
adult male 01day
20
adult male 05day
26
adult male 30day
26
adult female 01day
58
adult female 05day
61
adult female 30day
67
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
99
embryo 02-04hr
172
embryo 04-06hr
165
embryo 06-08hr
136
embryo 08-10hr
106
embryo 10-12hr
94
embryo 12-14hr
45
embryo 14-16hr
58
embryo 16-18hr
36
embryo 18-20hr
32
embryo 20-22hr
37
embryo 22-24hr
31
larva L1
37
larva L2
31
larva L3 12hr old
29
larva L3 puffstage 1-2
22
larva L3 puffstage 3-6
25
larva L3 puffstage 7-9
24
white prepupae new
23
white prepupae 12hr
27
white prepupae 24hr
32
pupae 2d postWPP
22
pupae 3d postWPP
14
pupae 4d postWPP
25
adult male 01day
20
adult male 05day
26
adult male 30day
26
adult female 01day
58
adult female 05day
61
adult female 30day
67
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
99
embryo 02-04hr
172
embryo 04-06hr
165
embryo 06-08hr
136
embryo 08-10hr
106
embryo 10-12hr
94
embryo 12-14hr
45
embryo 14-16hr
58
embryo 16-18hr
36
embryo 18-20hr
32
embryo 20-22hr
37
embryo 22-24hr
31
larva L1
37
larva L2
31
larva L3 12hr old
29
larva L3 puffstage 1-2
22
larva L3 puffstage 3-6
25
larva L3 puffstage 7-9
24
white prepupae new
23
white prepupae 12hr
27
white prepupae 24hr
32
pupae 2d postWPP
22
pupae 3d postWPP
14
pupae 4d postWPP
25
adult male 01day
20
adult male 05day
26
adult male 30day
26
adult female 01day
58
adult female 05day
61
adult female 30day
67
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(99)
embryo 02-04hr
(172)
embryo 04-06hr
(165)
embryo 06-08hr
(136)
embryo 08-10hr
(106)
embryo 10-12hr
(94)
embryo 12-14hr
(45)
embryo 14-16hr
(58)
embryo 16-18hr
(36)
embryo 18-20hr
32
embryo 20-22hr
(37)
embryo 22-24hr
31
larva L1
(37)
larva L2
31
larva L3 12hr old
29
larva L3 puffstage 1-2
22
larva L3 puffstage 3-6
25
larva L3 puffstage 7-9
24
white prepupae new
23
white prepupae 12hr
27
white prepupae 24hr
32
pupae 2d postWPP
22
pupae 3d postWPP
14
pupae 4d postWPP
25
adult male 01day
20
adult male 05day
26
adult male 30day
26
adult female 01day
(58)
adult female 05day
(61)
adult female 30day
(67)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
99
embryo 02-04hr
(172)
embryo 04-06hr
(165)
embryo 06-08hr
136
embryo 08-10hr
106
embryo 10-12hr
94
embryo 12-14hr
45
embryo 14-16hr
58
embryo 16-18hr
36
embryo 18-20hr
32
embryo 20-22hr
37
embryo 22-24hr
31
larva L1
37
larva L2
31
larva L3 12hr old
29
larva L3 puffstage 1-2
22
larva L3 puffstage 3-6
25
larva L3 puffstage 7-9
24
white prepupae new
23
white prepupae 12hr
27
white prepupae 24hr
32
pupae 2d postWPP
22
pupae 3d postWPP
14
pupae 4d postWPP
25
adult male 01day
20
adult male 05day
26
adult male 30day
26
adult female 01day
58
adult female 05day
61
adult female 30day
67
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
99
embryo 02-04hr
172
embryo 04-06hr
165
embryo 06-08hr
136
embryo 08-10hr
106
embryo 10-12hr
94
embryo 12-14hr
45
embryo 14-16hr
58
embryo 16-18hr
36
embryo 18-20hr
32
embryo 20-22hr
37
embryo 22-24hr
31
larva L1
37
larva L2
31
larva L3 12hr old
29
larva L3 puffstage 1-2
22
larva L3 puffstage 3-6
25
larva L3 puffstage 7-9
24
white prepupae new
23
white prepupae 12hr
27
white prepupae 24hr
32
pupae 2d postWPP
22
pupae 3d postWPP
14
pupae 4d postWPP
25
adult male 01day
20
adult male 05day
26
adult male 30day
26
adult female 01day
58
adult female 05day
61
adult female 30day
67
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
97
Schneider line 2 Sg4
59
embryonic 1182-4H
36
embryonic GM2
46
embryonic Kc167
79
embryonic S1
77
embryonic S3
42
leg disc CME L1
45
wing disc CME-W2
49
wing disc ML-DmD8
31
wing disc ML-DmD9
50
wing disc ML-DmD16-c3
39
wing disc ML-DmD21
75
wing disc ML-DmD32
55
haltere disc ML-DmD17-c3
45
eye-antennal disc ML-DmD11
62
antennal disc ML-DmD20-c5
91
mixed discs ML-DmD4-c1
27
CNS ML-DmBG1-c1
43
CNS ML-DmBG2-c2
29
tumorous blood cells mbn2
32
ovary fGS/OSS
32
ovary OSC
25
ovary OSS
8
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(97)
Schneider line 2 Sg4
(59)
embryonic 1182-4H
(36)
embryonic GM2
(46)
embryonic Kc167
(79)
embryonic S1
(77)
embryonic S3
(42)
leg disc CME L1
(45)
wing disc CME-W2
(49)
wing disc ML-DmD8
(31)
wing disc ML-DmD9
(50)
wing disc ML-DmD16-c3
(39)
wing disc ML-DmD21
(75)
wing disc ML-DmD32
(55)
haltere disc ML-DmD17-c3
(45)
eye-antennal disc ML-DmD11
(62)
antennal disc ML-DmD20-c5
(91)
mixed discs ML-DmD4-c1
(27)
CNS ML-DmBG1-c1
(43)
CNS ML-DmBG2-c2
(29)
tumorous blood cells mbn2
(32)
ovary fGS/OSS
(32)
ovary OSC
25
ovary OSS
8
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
97
Schneider line 2 Sg4
59
embryonic 1182-4H
36
embryonic GM2
46
embryonic Kc167
79
embryonic S1
77
embryonic S3
42
leg disc CME L1
45
wing disc CME-W2
49
wing disc ML-DmD8
31
wing disc ML-DmD9
50
wing disc ML-DmD16-c3
39
wing disc ML-DmD21
75
wing disc ML-DmD32
55
haltere disc ML-DmD17-c3
45
eye-antennal disc ML-DmD11
62
antennal disc ML-DmD20-c5
91
mixed discs ML-DmD4-c1
27
CNS ML-DmBG1-c1
43
CNS ML-DmBG2-c2
29
tumorous blood cells mbn2
32
ovary fGS/OSS
32
ovary OSC
25
ovary OSS
8
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
97
Schneider line 2 Sg4
59
embryonic 1182-4H
36
embryonic GM2
46
embryonic Kc167
79
embryonic S1
77
embryonic S3
42
leg disc CME L1
45
wing disc CME-W2
49
wing disc ML-DmD8
31
wing disc ML-DmD9
50
wing disc ML-DmD16-c3
39
wing disc ML-DmD21
75
wing disc ML-DmD32
55
haltere disc ML-DmD17-c3
45
eye-antennal disc ML-DmD11
62
antennal disc ML-DmD20-c5
91
mixed discs ML-DmD4-c1
27
CNS ML-DmBG1-c1
43
CNS ML-DmBG2-c2
29
tumorous blood cells mbn2
32
ovary fGS/OSS
32
ovary OSC
25
ovary OSS
8
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
97
Schneider line 2 Sg4
59
embryonic 1182-4H
36
embryonic GM2
46
embryonic Kc167
79
embryonic S1
77
embryonic S3
42
leg disc CME L1
45
wing disc CME-W2
49
wing disc ML-DmD8
31
wing disc ML-DmD9
50
wing disc ML-DmD16-c3
39
wing disc ML-DmD21
75
wing disc ML-DmD32
55
haltere disc ML-DmD17-c3
45
eye-antennal disc ML-DmD11
62
antennal disc ML-DmD20-c5
91
mixed discs ML-DmD4-c1
27
CNS ML-DmBG1-c1
43
CNS ML-DmBG2-c2
29
tumorous blood cells mbn2
32
ovary fGS/OSS
32
ovary OSC
25
ovary OSS
8
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(97)
Schneider line 2 Sg4
(59)
embryonic 1182-4H
(36)
embryonic GM2
(46)
embryonic Kc167
(79)
embryonic S1
(77)
embryonic S3
(42)
leg disc CME L1
(45)
wing disc CME-W2
(49)
wing disc ML-DmD8
31
wing disc ML-DmD9
(50)
wing disc ML-DmD16-c3
(39)
wing disc ML-DmD21
(75)
wing disc ML-DmD32
(55)
haltere disc ML-DmD17-c3
(45)
eye-antennal disc ML-DmD11
(62)
antennal disc ML-DmD20-c5
(91)
mixed discs ML-DmD4-c1
27
CNS ML-DmBG1-c1
(43)
CNS ML-DmBG2-c2
29
tumorous blood cells mbn2
32
ovary fGS/OSS
32
ovary OSC
25
ovary OSS
8
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
97
Schneider line 2 Sg4
59
embryonic 1182-4H
36
embryonic GM2
46
embryonic Kc167
79
embryonic S1
77
embryonic S3
42
leg disc CME L1
45
wing disc CME-W2
49
wing disc ML-DmD8
31
wing disc ML-DmD9
50
wing disc ML-DmD16-c3
39
wing disc ML-DmD21
75
wing disc ML-DmD32
55
haltere disc ML-DmD17-c3
45
eye-antennal disc ML-DmD11
62
antennal disc ML-DmD20-c5
91
mixed discs ML-DmD4-c1
27
CNS ML-DmBG1-c1
43
CNS ML-DmBG2-c2
29
tumorous blood cells mbn2
32
ovary fGS/OSS
32
ovary OSC
25
ovary OSS
8
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
97
Schneider line 2 Sg4
59
embryonic 1182-4H
36
embryonic GM2
46
embryonic Kc167
79
embryonic S1
77
embryonic S3
42
leg disc CME L1
45
wing disc CME-W2
49
wing disc ML-DmD8
31
wing disc ML-DmD9
50
wing disc ML-DmD16-c3
39
wing disc ML-DmD21
75
wing disc ML-DmD32
55
haltere disc ML-DmD17-c3
45
eye-antennal disc ML-DmD11
62
antennal disc ML-DmD20-c5
91
mixed discs ML-DmD4-c1
27
CNS ML-DmBG1-c1
43
CNS ML-DmBG2-c2
29
tumorous blood cells mbn2
32
ovary fGS/OSS
32
ovary OSC
25
ovary OSS
8
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
17
cold shock, 4-day adult
12
heat shock, 4-day adult
23
Cadmium 50 mM 6 hrs, larvae L3
19
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
20
Cadmium 100 mM 48 hrs, 4-day adult
28
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
13
Zinc 4.5 mM 48 hrs, 4-day adult
9
Ethanol 2.5% 3 hrs, larvae L3
41
Ethanol 5% 3 hrs, larvae L3
15
Ethanol 10% 3 hrs, larvae L3
17
Caffeine 1.5 mg/ml 4 hrs, larvae L3
16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
28
Caffeine 25 mg/ml 48 hrs, 4-day adult
12
Paraquat 5 mM 48 hrs, 4-day adult
28
Paraquat 10 mM 48 hrs, 4-day adult
36
Rotenone 2 μg 12 hrs, larvae L3
18
Rotenone 8 μg 12 hrs, larvae L3
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
17
cold shock, 4-day adult
12
heat shock, 4-day adult
23
Cadmium 50 mM 6 hrs, larvae L3
19
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
20
Cadmium 100 mM 48 hrs, 4-day adult
(28)
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
13
Zinc 4.5 mM 48 hrs, 4-day adult
9
Ethanol 2.5% 3 hrs, larvae L3
(41)
Ethanol 5% 3 hrs, larvae L3
15
Ethanol 10% 3 hrs, larvae L3
17
Caffeine 1.5 mg/ml 4 hrs, larvae L3
16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(28)
Caffeine 25 mg/ml 48 hrs, 4-day adult
12
Paraquat 5 mM 48 hrs, 4-day adult
(28)
Paraquat 10 mM 48 hrs, 4-day adult
(36)
Rotenone 2 μg 12 hrs, larvae L3
18
Rotenone 8 μg 12 hrs, larvae L3
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
17
cold shock, 4-day adult
12
heat shock, 4-day adult
23
Cadmium 50 mM 6 hrs, larvae L3
19
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
20
Cadmium 100 mM 48 hrs, 4-day adult
28
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
13
Zinc 4.5 mM 48 hrs, 4-day adult
9
Ethanol 2.5% 3 hrs, larvae L3
41
Ethanol 5% 3 hrs, larvae L3
15
Ethanol 10% 3 hrs, larvae L3
17
Caffeine 1.5 mg/ml 4 hrs, larvae L3
16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
28
Caffeine 25 mg/ml 48 hrs, 4-day adult
12
Paraquat 5 mM 48 hrs, 4-day adult
28
Paraquat 10 mM 48 hrs, 4-day adult
36
Rotenone 2 μg 12 hrs, larvae L3
18
Rotenone 8 μg 12 hrs, larvae L3
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
17
cold shock, 4-day adult
12
heat shock, 4-day adult
23
Cadmium 50 mM 6 hrs, larvae L3
19
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
20
Cadmium 100 mM 48 hrs, 4-day adult
28
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
13
Zinc 4.5 mM 48 hrs, 4-day adult
9
Ethanol 2.5% 3 hrs, larvae L3
41
Ethanol 5% 3 hrs, larvae L3
15
Ethanol 10% 3 hrs, larvae L3
17
Caffeine 1.5 mg/ml 4 hrs, larvae L3
16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
28
Caffeine 25 mg/ml 48 hrs, 4-day adult
12
Paraquat 5 mM 48 hrs, 4-day adult
28
Paraquat 10 mM 48 hrs, 4-day adult
36
Rotenone 2 μg 12 hrs, larvae L3
18
Rotenone 8 μg 12 hrs, larvae L3
22
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
17
cold shock, 4-day adult
12
heat shock, 4-day adult
23
Cadmium 50 mM 6 hrs, larvae L3
19
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
20
Cadmium 100 mM 48 hrs, 4-day adult
28
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
13
Zinc 4.5 mM 48 hrs, 4-day adult
9
Ethanol 2.5% 3 hrs, larvae L3
41
Ethanol 5% 3 hrs, larvae L3
15
Ethanol 10% 3 hrs, larvae L3
17
Caffeine 1.5 mg/ml 4 hrs, larvae L3
16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
28
Caffeine 25 mg/ml 48 hrs, 4-day adult
12
Paraquat 5 mM 48 hrs, 4-day adult
28
Paraquat 10 mM 48 hrs, 4-day adult
36
Rotenone 2 μg 12 hrs, larvae L3
18
Rotenone 8 μg 12 hrs, larvae L3
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
17
cold shock, 4-day adult
12
heat shock, 4-day adult
23
Cadmium 50 mM 6 hrs, larvae L3
19
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
20
Cadmium 100 mM 48 hrs, 4-day adult
28
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
13
Zinc 4.5 mM 48 hrs, 4-day adult
9
Ethanol 2.5% 3 hrs, larvae L3
(41)
Ethanol 5% 3 hrs, larvae L3
15
Ethanol 10% 3 hrs, larvae L3
17
Caffeine 1.5 mg/ml 4 hrs, larvae L3
16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
28
Caffeine 25 mg/ml 48 hrs, 4-day adult
12
Paraquat 5 mM 48 hrs, 4-day adult
28
Paraquat 10 mM 48 hrs, 4-day adult
(36)
Rotenone 2 μg 12 hrs, larvae L3
18
Rotenone 8 μg 12 hrs, larvae L3
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
17
cold shock, 4-day adult
12
heat shock, 4-day adult
23
Cadmium 50 mM 6 hrs, larvae L3
19
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
20
Cadmium 100 mM 48 hrs, 4-day adult
28
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
13
Zinc 4.5 mM 48 hrs, 4-day adult
9
Ethanol 2.5% 3 hrs, larvae L3
41
Ethanol 5% 3 hrs, larvae L3
15
Ethanol 10% 3 hrs, larvae L3
17
Caffeine 1.5 mg/ml 4 hrs, larvae L3
16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
28
Caffeine 25 mg/ml 48 hrs, 4-day adult
12
Paraquat 5 mM 48 hrs, 4-day adult
28
Paraquat 10 mM 48 hrs, 4-day adult
36
Rotenone 2 μg 12 hrs, larvae L3
18
Rotenone 8 μg 12 hrs, larvae L3
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
17
cold shock, 4-day adult
12
heat shock, 4-day adult
23
Cadmium 50 mM 6 hrs, larvae L3
19
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
20
Cadmium 100 mM 48 hrs, 4-day adult
28
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
13
Zinc 4.5 mM 48 hrs, 4-day adult
9
Ethanol 2.5% 3 hrs, larvae L3
41
Ethanol 5% 3 hrs, larvae L3
15
Ethanol 10% 3 hrs, larvae L3
17
Caffeine 1.5 mg/ml 4 hrs, larvae L3
16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
28
Caffeine 25 mg/ml 48 hrs, 4-day adult
12
Paraquat 5 mM 48 hrs, 4-day adult
28
Paraquat 10 mM 48 hrs, 4-day adult
36
Rotenone 2 μg 12 hrs, larvae L3
18
Rotenone 8 μg 12 hrs, larvae L3
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 3 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 4 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Disrupted in Transgenic Constructs & Insertions
Transgenic Constructs Insertions insertion of mobile activating element
Gene Ontology: Function, Process
& Cellular Component ( 4 unique terms )There is no information supporting a
molecular function term for this gene.
(Based on a review of available data before: 2006)
Terms Based on
Experimental Evidence ( 4 terms ) Molecular Function ( 0 terms) Biological Process inferred from mutant phenotype
inferred from genetic interaction with
W inferred from mutant phenotype
inferred from genetic interaction with
puc Cellular Component inferred from direct assay
Terms Based on Predictions or
Assertions ( 1 term ) Molecular Function ( 0 terms) Biological Process ( 0 terms) Cellular Component inferred from sequence or structural similarity with
UniProtKB:Q6NYC1
(assigned by UniProtKB)
Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
experimental knowledge based
experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
experimental knowledge based
experimental knowledge based
experimental knowledge based
experimental knowledge based
experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
experimental knowledge based
experimental knowledge based
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (39)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG6JHD1N )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG6NGGWC )
Aedes aegypti
Yellow fever mosquito
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG69W1B1 )
Apis mellifera
Western honey bee
Amel\GB46775
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG003028
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH13802
Atta cephalotes
Leafcutter ant
Acep\ACEP19226
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO14360
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL16545
Linepithema humile
Argentine ant
Lhum\LH12569
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB12153
Solenopsis invicta
Red fire ant
Sinv\SINV22638
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG60000W )
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa
(EOG647TN2 )
Caenorhabditis elegans
Nematode
Strongylocentrotus purpuratus
Purple sea urchin
Xenopus tropicalis
Western clawed frog
Gallus gallus
Domestic chicken
Rattus norvegicus
Norway rat
Human Orthologs (1)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 4 )Bloomington VDRC Genomic Clones ( 1 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 42 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for identity of: PSR CG5383
Source for database merge of Source for merge of: PSR BEST:LD22859
Additional comments Other Comments PSR is needed in wild-type cells for the death of Minute neighbours in cell competition experiments.
Identification: in a screen for genes required for the phagocytosis of apoptotic cells in the Drosophila embryo using a panel of Drosophila strains carrying genomic deletions. Several candidate deletions were identified that displayed potential defects in this process. One of these was a large deletion that included the Drosophila homolog of the phosphatidylserine receptor (dPSR).
May function to protect from death in Drosophila.
External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
- A cyberspace guide to Drosophila development and metazoan evolution
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 10 )Reported As Symbol Synonym Name Synonym phosphatidylserine receptor
phosphatidyl-serine receptor
Secondary FlyBase
IDs References ( 31 )Generate a list of List References by type
Recent research papers ( 3 )
Lolo et al., 2012, Cell Rep. 2(3): 526--539Cell competition time line: winners kill losers, which are extruded and engulfed by hemocytes. [FBrf0220993] Cernilogar et al., 2011, Nature 480(7377): 391--395Chromatin-associated RNA interference components contribute to transcriptional regulation in Drosophila. [FBrf0216979] Curtis et al., 2011, Dev. Biol. 350(2): 534--547Histone lysine demethylases function as co-repressors of SWI/SNF remodeling activities during Drosophila wing development. [FBrf0212876]
Recent reviews (0)
All reviews listed in FlyBase were published before 2011