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Gene Dmel\mats

General Information
Symbol	Dmel\mats	Species	D. melanogaster
Name	mob as tumor suppressor	Annotation symbol	CG13852
Feature type	protein_coding_gene	FlyBase ID	FBgn0038965
Gene Model Status	Current	Stock availability	7 publicly available
Also Known As	DMob1
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	94A12-94A12	Sequence location	3R:18,246,877..18,248,568 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene mob as tumor suppressor is referred to in FlyBase by the symbol Dmel\mats (CG13852, FBgn0038965). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: apoptotic process; cell proliferation; signal transduction. 11 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum; denticle; imaginal disc. It has one annotated transcript and one annotated polypeptide. Protein features are: Mob1/phocein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, larval Malpighian tubules, adult heart, larval fat body, larval salivary gland, larval trachea, adult ovary, adult male reproductive system, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1632919_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of mats. Gene sequence location is 3R:18246877..18248568.
External Summaries
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10	References Truscott et al., 2011, Genes Dev. 25(17): 1820--1834
FB2012_01	References Poon et al., 2011, Dev. Cell 21(5): 896--906 Sequence features BKN20236 HFA14702 HFA13562
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 94A12-94A12   Limits computationally determined from genome sequence between P{PZ}l(3)rQ178rQ178 and P{lacW}Dph5L4910
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\mats for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) mats-RA FBtr0084229  NM_142784   1266   219
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein mats-PA   FBpp0083624   25.2   219   6.60     NP_651041   AAF55993
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Mob1/phocein (IPR005301)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201430   AA696512   AA735696   AE014297 AAF55993   AI256930   AI515650   AW943919   AX094179   AY061520 AAL29068   BF502994   BI162884   BI172583   CO279736   CO282257   CO308509   CO308753   CO323292   CO325464   CO333051   CZ480841   CZ480842   CZ480844   EC060765   EC074582   EC079335   EC238196   EC238220   EC249027   EC250239
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q95RA8
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0038965    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0038965 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0038965 expression level Developmental Stage   Expression Level embryo 00-02hr    5664 embryo 02-04hr    2058 embryo 04-06hr    1619 embryo 06-08hr    3391 embryo 08-10hr    3760 embryo 10-12hr    3504 embryo 12-14hr    3634 embryo 14-16hr    3894 embryo 16-18hr    2650 embryo 18-20hr    1709 embryo 20-22hr    1221 embryo 22-24hr    1355 larva L1    1328 larva L2    1501 larva L3 12hr old    1164 larva L3 puffstage 1-2    1706 larva L3 puffstage 3-6    2853 larva L3 puffstage 7-9    5227 white prepupae new    7867 white prepupae 12hr    5790 white prepupae 24hr    4461 pupae 2d postWPP    3676 pupae 3d postWPP    1862 pupae 4d postWPP    1497 adult male 01day    1636 adult male 05day    1980 adult male 30day    1777 adult female 01day    2837 adult female 05day    4584 adult female 30day    4520 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (5664) embryo 02-04hr  (2058) embryo 04-06hr  (1619) embryo 06-08hr  (3391) embryo 08-10hr  (3760) embryo 10-12hr  (3504) embryo 12-14hr  (3634) embryo 14-16hr  (3894) embryo 16-18hr  (2650) embryo 18-20hr  (1709) embryo 20-22hr  (1221) embryo 22-24hr  (1355) larva L1  (1328) larva L2  (1501) larva L3 12hr old  (1164) larva L3 puffstage 1-2  (1706) larva L3 puffstage 3-6  (2853) larva L3 puffstage 7-9  (5227) white prepupae new  (7867) white prepupae 12hr  (5790) white prepupae 24hr  (4461) pupae 2d postWPP  (3676) pupae 3d postWPP  (1862) pupae 4d postWPP  (1497) adult male 01day  (1636) adult male 05day  (1980) adult male 30day  (1777) adult female 01day  (2837) adult female 05day  (4584) adult female 30day  (4520) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (5664) embryo 02-04hr  (2058) embryo 04-06hr  (1619) embryo 06-08hr  (3391) embryo 08-10hr  (3760) embryo 10-12hr  (3504) embryo 12-14hr  (3634) embryo 14-16hr  (3894) embryo 16-18hr  (2650) embryo 18-20hr  (1709) embryo 20-22hr    1221 embryo 22-24hr    1355 larva L1    1328 larva L2  1501 larva L3 12hr old    1164 larva L3 puffstage 1-2  (1706) larva L3 puffstage 3-6  (2853) larva L3 puffstage 7-9  (5227) white prepupae new  (7867) white prepupae 12hr  (5790) white prepupae 24hr  (4461) pupae 2d postWPP  (3676) pupae 3d postWPP  (1862) pupae 4d postWPP  1497 adult male 01day  (1636) adult male 05day  (1980) adult male 30day  (1777) adult female 01day  (2837) adult female 05day  (4584) adult female 30day  (4520) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5664 embryo 02-04hr    2058 embryo 04-06hr    1619 embryo 06-08hr    3391 embryo 08-10hr    3760 embryo 10-12hr    3504 embryo 12-14hr    3634 embryo 14-16hr    3894 embryo 16-18hr    2650 embryo 18-20hr    1709 embryo 20-22hr    1221 embryo 22-24hr    1355 larva L1    1328 larva L2    1501 larva L3 12hr old    1164 larva L3 puffstage 1-2    1706 larva L3 puffstage 3-6    2853 larva L3 puffstage 7-9    5227 white prepupae new    7867 white prepupae 12hr    5790 white prepupae 24hr    4461 pupae 2d postWPP    3676 pupae 3d postWPP    1862 pupae 4d postWPP    1497 adult male 01day    1636 adult male 05day    1980 adult male 30day    1777 adult female 01day    2837 adult female 05day    4584 adult female 30day    4520 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5664 embryo 02-04hr    2058 embryo 04-06hr    1619 embryo 06-08hr    3391 embryo 08-10hr    3760 embryo 10-12hr    3504 embryo 12-14hr    3634 embryo 14-16hr    3894 embryo 16-18hr    2650 embryo 18-20hr    1709 embryo 20-22hr    1221 embryo 22-24hr    1355 larva L1    1328 larva L2    1501 larva L3 12hr old    1164 larva L3 puffstage 1-2    1706 larva L3 puffstage 3-6    2853 larva L3 puffstage 7-9    5227 white prepupae new    7867 white prepupae 12hr    5790 white prepupae 24hr    4461 pupae 2d postWPP    3676 pupae 3d postWPP    1862 pupae 4d postWPP    1497 adult male 01day    1636 adult male 05day    1980 adult male 30day    1777 adult female 01day    2837 adult female 05day    4584 adult female 30day    4520 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0038965 expression level Developmental Stage   Expression Level embryo 00-02hr    5664 embryo 02-04hr    2058 embryo 04-06hr    1619 embryo 06-08hr    3391 embryo 08-10hr    3760 embryo 10-12hr    3504 embryo 12-14hr    3634 embryo 14-16hr    3894 embryo 16-18hr    2650 embryo 18-20hr    1709 embryo 20-22hr    1221 embryo 22-24hr    1355 larva L1    1328 larva L2    1501 larva L3 12hr old    1164 larva L3 puffstage 1-2    1706 larva L3 puffstage 3-6    2853 larva L3 puffstage 7-9    5227 white prepupae new    7867 white prepupae 12hr    5790 white prepupae 24hr    4461 pupae 2d postWPP    3676 pupae 3d postWPP    1862 pupae 4d postWPP    1497 adult male 01day    1636 adult male 05day    1980 adult male 30day    1777 adult female 01day    2837 adult female 05day    4584 adult female 30day    4520 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (5664) embryo 02-04hr  (2058) embryo 04-06hr  (1619) embryo 06-08hr  (3391) embryo 08-10hr  (3760) embryo 10-12hr  (3504) embryo 12-14hr  (3634) embryo 14-16hr  (3894) embryo 16-18hr  (2650) embryo 18-20hr  (1709) embryo 20-22hr  (1221) embryo 22-24hr  (1355) larva L1  (1328) larva L2  (1501) larva L3 12hr old  (1164) larva L3 puffstage 1-2  (1706) larva L3 puffstage 3-6  (2853) larva L3 puffstage 7-9  (5227) white prepupae new  (7867) white prepupae 12hr  (5790) white prepupae 24hr  (4461) pupae 2d postWPP  (3676) pupae 3d postWPP  (1862) pupae 4d postWPP  (1497) adult male 01day  (1636) adult male 05day  (1980) adult male 30day  (1777) adult female 01day  (2837) adult female 05day  (4584) adult female 30day  (4520) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (5664) embryo 02-04hr  2058 embryo 04-06hr  1619 embryo 06-08hr  (3391) embryo 08-10hr  (3760) embryo 10-12hr  (3504) embryo 12-14hr  (3634) embryo 14-16hr  (3894) embryo 16-18hr  (2650) embryo 18-20hr  1709 embryo 20-22hr    1221 embryo 22-24hr    1355 larva L1    1328 larva L2  1501 larva L3 12hr old    1164 larva L3 puffstage 1-2  1706 larva L3 puffstage 3-6  (2853) larva L3 puffstage 7-9  (5227) white prepupae new  (7867) white prepupae 12hr  (5790) white prepupae 24hr  (4461) pupae 2d postWPP  (3676) pupae 3d postWPP  1862 pupae 4d postWPP  1497 adult male 01day  1636 adult male 05day  1980 adult male 30day  1777 adult female 01day  (2837) adult female 05day  (4584) adult female 30day  (4520) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5664 embryo 02-04hr    2058 embryo 04-06hr    1619 embryo 06-08hr    3391 embryo 08-10hr    3760 embryo 10-12hr    3504 embryo 12-14hr    3634 embryo 14-16hr    3894 embryo 16-18hr    2650 embryo 18-20hr    1709 embryo 20-22hr    1221 embryo 22-24hr    1355 larva L1    1328 larva L2    1501 larva L3 12hr old    1164 larva L3 puffstage 1-2    1706 larva L3 puffstage 3-6    2853 larva L3 puffstage 7-9    5227 white prepupae new    7867 white prepupae 12hr    5790 white prepupae 24hr    4461 pupae 2d postWPP    3676 pupae 3d postWPP    1862 pupae 4d postWPP    1497 adult male 01day    1636 adult male 05day    1980 adult male 30day    1777 adult female 01day    2837 adult female 05day    4584 adult female 30day    4520 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5664 embryo 02-04hr    2058 embryo 04-06hr    1619 embryo 06-08hr    3391 embryo 08-10hr    3760 embryo 10-12hr    3504 embryo 12-14hr    3634 embryo 14-16hr    3894 embryo 16-18hr    2650 embryo 18-20hr    1709 embryo 20-22hr    1221 embryo 22-24hr    1355 larva L1    1328 larva L2    1501 larva L3 12hr old    1164 larva L3 puffstage 1-2    1706 larva L3 puffstage 3-6    2853 larva L3 puffstage 7-9    5227 white prepupae new    7867 white prepupae 12hr    5790 white prepupae 24hr    4461 pupae 2d postWPP    3676 pupae 3d postWPP    1862 pupae 4d postWPP    1497 adult male 01day    1636 adult male 05day    1980 adult male 30day    1777 adult female 01day    2837 adult female 05day    4584 adult female 30day    4520 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0038965    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0038965 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, larval Malpighian tubules, adult heart, larval fat body, larval salivary gland, larval trachea, adult ovary, adult male reproductive system, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0038965 expression level Tissue   Expression Level Larval Central Nervous System    138.65 Larval Midgut    99.2 Larval Hindgut    89.2 Larval Malpighian Tubules    224.8 Larval Fat Body    134.4 Larval Salivary Gland    156.7 Larval Trachea    129.325 Larval Carcass    103.025 Adult Head    75.6 Adult Eye    71.85 Adult Brain    67.9 Adult Thoracic-Abdominal Ganglion    50.9 Adult Crop    133.2 Adult Midgut    86.9 Adult Hindgut    82.6 Adult Malpighian Tubules    76.4 Adult Fat Body    88.4 Adult Salivary Gland    83.4 Adult Heart    131.925 Adult VirginFemale Spermatheca    72.3 Adult InseminatedFemale Spermatheca    68.1 Adult Ovary    291.7 Adult Testis    178.7 Adult Male Accessory Gland    103.9 Adult Carcass    72.7 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    138.65 Larval Midgut    99.2 Larval Hindgut    89.2 Larval Malpighian Tubules    224.8 Larval Fat Body    134.4 Larval Salivary Gland    156.7 Larval Trachea    129.325 Larval Carcass    103.025 Adult Head    75.6 Adult Eye    71.85 Adult Brain    67.9 Adult Thoracic-Abdominal Ganglion    50.9 Adult Crop    133.2 Adult Midgut    86.9 Adult Hindgut    82.6 Adult Malpighian Tubules    76.4 Adult Fat Body    88.4 Adult Salivary Gland    83.4 Adult Heart    131.925 Adult VirginFemale Spermatheca    72.3 Adult InseminatedFemale Spermatheca    68.1 Adult Ovary    291.7 Adult Testis    178.7 Adult Male Accessory Gland    103.9 Adult Carcass    72.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    138.65 Larval Midgut    99.2 Larval Hindgut    89.2 Larval Malpighian Tubules    224.8 Larval Fat Body    134.4 Larval Salivary Gland    156.7 Larval Trachea    129.325 Larval Carcass    103.025 Adult Head    75.6 Adult Eye    71.85 Adult Brain    67.9 Adult Thoracic-Abdominal Ganglion    50.9 Adult Crop    133.2 Adult Midgut    86.9 Adult Hindgut    82.6 Adult Malpighian Tubules    76.4 Adult Fat Body    88.4 Adult Salivary Gland    83.4 Adult Heart    131.925 Adult VirginFemale Spermatheca    72.3 Adult InseminatedFemale Spermatheca    68.1 Adult Ovary    291.7 Adult Testis    178.7 Adult Male Accessory Gland    103.9 Adult Carcass    72.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    138.65 Larval Midgut    99.2 Larval Hindgut    89.2 Larval Malpighian Tubules    224.8 Larval Fat Body    134.4 Larval Salivary Gland    156.7 Larval Trachea    129.325 Larval Carcass    103.025 Adult Head    75.6 Adult Eye    71.85 Adult Brain    67.9 Adult Thoracic-Abdominal Ganglion    50.9 Adult Crop    133.2 Adult Midgut    86.9 Adult Hindgut    82.6 Adult Malpighian Tubules    76.4 Adult Fat Body    88.4 Adult Salivary Gland    83.4 Adult Heart    131.925 Adult VirginFemale Spermatheca    72.3 Adult InseminatedFemale Spermatheca    68.1 Adult Ovary    291.7 Adult Testis    178.7 Adult Male Accessory Gland    103.9 Adult Carcass    72.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0038965 expression level Tissue   Expression Level Larval Central Nervous System    138.65 Larval Midgut    99.2 Larval Hindgut    89.2 Larval Malpighian Tubules    224.8 Larval Fat Body    134.4 Larval Salivary Gland    156.7 Larval Trachea    129.325 Larval Carcass    103.025 Adult Head    75.6 Adult Eye    71.85 Adult Brain    67.9 Adult Thoracic-Abdominal Ganglion    50.9 Adult Crop    133.2 Adult Midgut    86.9 Adult Hindgut    82.6 Adult Malpighian Tubules    76.4 Adult Fat Body    88.4 Adult Salivary Gland    83.4 Adult Heart    131.925 Adult VirginFemale Spermatheca    72.3 Adult InseminatedFemale Spermatheca    68.1 Adult Ovary    291.7 Adult Testis    178.7 Adult Male Accessory Gland    103.9 Adult Carcass    72.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    138.65 Larval Midgut    99.2 Larval Hindgut    89.2 Larval Malpighian Tubules    224.8 Larval Fat Body    134.4 Larval Salivary Gland    156.7 Larval Trachea    129.325 Larval Carcass    103.025 Adult Head    75.6 Adult Eye    71.85 Adult Brain    67.9 Adult Thoracic-Abdominal Ganglion    50.9 Adult Crop    133.2 Adult Midgut    86.9 Adult Hindgut    82.6 Adult Malpighian Tubules    76.4 Adult Fat Body    88.4 Adult Salivary Gland    83.4 Adult Heart    131.925 Adult VirginFemale Spermatheca    72.3 Adult InseminatedFemale Spermatheca    68.1 Adult Ovary    291.7 Adult Testis    178.7 Adult Male Accessory Gland    103.9 Adult Carcass    72.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    138.65 Larval Midgut    99.2 Larval Hindgut    89.2 Larval Malpighian Tubules    224.8 Larval Fat Body    134.4 Larval Salivary Gland    156.7 Larval Trachea    129.325 Larval Carcass    103.025 Adult Head    75.6 Adult Eye    71.85 Adult Brain    67.9 Adult Thoracic-Abdominal Ganglion    50.9 Adult Crop    133.2 Adult Midgut    86.9 Adult Hindgut    82.6 Adult Malpighian Tubules    76.4 Adult Fat Body    88.4 Adult Salivary Gland    83.4 Adult Heart    131.925 Adult VirginFemale Spermatheca    72.3 Adult InseminatedFemale Spermatheca    68.1 Adult Ovary    291.7 Adult Testis    178.7 Adult Male Accessory Gland    103.9 Adult Carcass    72.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    138.65 Larval Midgut    99.2 Larval Hindgut    89.2 Larval Malpighian Tubules    224.8 Larval Fat Body    134.4 Larval Salivary Gland    156.7 Larval Trachea    129.325 Larval Carcass    103.025 Adult Head    75.6 Adult Eye    71.85 Adult Brain    67.9 Adult Thoracic-Abdominal Ganglion    50.9 Adult Crop    133.2 Adult Midgut    86.9 Adult Hindgut    82.6 Adult Malpighian Tubules    76.4 Adult Fat Body    88.4 Adult Salivary Gland    83.4 Adult Heart    131.925 Adult VirginFemale Spermatheca    72.3 Adult InseminatedFemale Spermatheca    68.1 Adult Ovary    291.7 Adult Testis    178.7 Adult Male Accessory Gland    103.9 Adult Carcass    72.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    75.6   NA  Eye    71.85   NA  Brain    67.9   138.65  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    50.9   NA  Crop    133.2   99.2  Midgut    86.9   89.2  Hindgut    82.6   224.8  Malpighian Tubules    76.4   134.4  Fat Body    88.4   156.7  Salivary Gland    83.4   NA  Heart    131.925   129.325  Trachea    NA   NA  VirginFemale Spermatheca    72.3   NA  InseminatedFemale Spermatheca    68.1   NA  Ovary    291.7   NA  Testis    178.7   NA  Male Accessory Gland    103.9   103.025  Carcass    72.7 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_23
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038965 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG13852-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for mats Stages(s) 1-3 Stages(s) 4-6 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal matse03077 lethal (with Df(3R)Exel6191) matse03077 lethal (with matse235) matse03077 lethal (with matse03077) matse235 lethal | recessive | second instar larval stage matse235 matsroo viable, with Scer\GAL4ey.PH matsScer\UAS.cLa viable, with Scer\GAL4pnr-MD237 matsGD8136 Other Phenotypes Allele body color defective, with Scer\GAL4pnr-MD237 matsGD8136 body color defective | somatic clone matse03077 mitotic cell cycle defective | somatic clone matse235 neuroanatomy defective | somatic clone matsunspecified tumorigenic | somatic clone matse235 matsroo visible, with Scer\GAL4pnr-MD237 matsGD8136 visible | somatic clone matse03077 wild-type, with Scer\GAL4ey.PH matsScer\UAS.cLa Phenotype manifest in Allele denticle matse03077 imaginal disc matsunspecified mesothoracic tergum, with Scer\GAL4pnr-MD237 matsGD8136 mushroom body | somatic clone matsunspecified trichogen cell, with Scer\GAL4pnr-MD237 matsGD8136 wing | somatic clone matse03077 wing hair | somatic clone matse03077 wing hair | somatic clone | supernumerary matse03077
Classical Alleles ( 6 )
For All Classical Alleles Show
Allele of mats Class Mutagen Stocks Known lesion matse03077 loss of function allele piggyBac transposase 2 -- matse03078 piggyBac transposase 0 -- matse235 P-element activity 0 Yes matsPBrv piggyBac transposase 0 -- matsroo transposable element activity 0 Yes matsunspecified 0 --
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of mats Class Mutagen Stocks Known lesion matsGD8136 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes matsHMS00475 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes matsJF03246 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes matsKK100140 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes matsScer\UAS.cLa in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6191 (Ryder, 2004.4.26) Df(3R)matse325 (Lai et al., 2005)
Partially disrupted in	Df(3R)matse325 (Lai et al., 2005)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD8136} NA P{KK100140} NA P{TRiP.HMS00475} NA P{TRiP.JF03246} NA P{UAS-mats.L} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{RB}matse03077 NA PBac{RB}matse03078 NA roo{}matsroo NA
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
	There is no information supporting a cellular component term for this gene. (Based on a review of available data on: 2007-02-19)
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function
CV term Evidence References
protein binding inferred from physical interaction with UniProtKB:Q9NBK5 (assigned by UniProtKB) (He et al., 2005) inferred from physical interaction with UniProtKB:Q9VA38 (assigned by UniProtKB) (Lai et al., 2005)
Biological Process
CV term Evidence References
apoptotic process inferred from mutant phenotype (assigned by UniProtKB) (Lai et al., 2005) cell proliferation inferred from mutant phenotype (assigned by UniProtKB) (Lai et al., 2005) signal transduction inferred from mutant phenotype (assigned by UniProtKB) (He et al., 2005)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions mats allele Gene References matse325 wts (Lai et al., 2005) matsScer\UAS.cLa wts (Lai et al., 2005) unspecified trc (He et al., 2005)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 67590 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0038965 DroID - A comprehensive database of gene and protein interactions. • FBgn0038965 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42634
Orthologs
Genome-wide drosophilid orthologs	Dana\GF18448 Dere\GG11134 Dgri\GH13388 Dmoj\GI22385 Dper\GL24215 Dpse\GA26541 Dsec\GM26432 Dsim\GD20949 Dvir\GJ24418 Dwil\GK13074 Dyak\GE10299
Curated drosophilid orthologs	Dpse\GA12572
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL010046-PB Aedes aegypti (mosquito) AGAP002066-PA Anopheles gambiae (mosquito) XP_393046.2 Apis mellifera (honey bee) XP_001949733.1 Acyrthosiphon pisum (pea aphid) At5g45550.1 Arabidopsis thaliana (wall cress) 30301 Batrachochytrium dendrobatidis (chytrid fungus) 131298 Branchiostoma floridae (lancelet) BGIBMGA013463-PA Bombyx mori (silk worm) ENSBTAP00000021671 Bos taurus (bovine) CAL0006122 Candida albicans (a form of yeast) ENSCAFP00000004332 Canis familiaris (dog) ENSCAFP00000012856 Canis familiaris (dog) CAGL0G02805g Candida glabrata (haploid yeast) ENSCINP00000006737 Ciona intestinalis (sea squirt) cn12194 Cryptococcus neoformans (yeast-like fungus) CPIJ003355 Culex pipens (mosquito) ENSCPOP00000010425 Cavia porcellus (guinea pig) 133994 Chlamidomonas reinhardtii (green alga) ENSCSAVP00000019672 Ciona savignyi (sedentary tunicate) 21709 Capitella spl (polychaete worm) DDB0232218 Dictyostelium discoideum (amoeba) DEHA2A06600g Debaryomyces Hansenii (yeast) 223739 Daphnia pulex (daphnia) ENSDARP00000088385 Danio rerio (zebra fish) ENSECAP00000021254 Equus caballus (horse) XP_650241 Entamoeba histolytica (anaerobic protozoan) XP_653257 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000011015 Gymnopilus aculeatus (mushroom) ENSGACP00000020943 Gymnopilus aculeatus (mushroom) ENSGALP00000018856 Gallus gallus (chicken) GL50803_11044 Giardia lamblia (flagellated protozoan) 185118 Hypsipyla robusta (cedar shoot borer) ENSP00000310189 Homo sapiens (human) ISCW013173-PA Ixodes scapularis (deer tick) KLLA0F03795g Kluyveromyces lactis (yeast) 238983 Lottia gigantea (owl limpet) LmjF06.0960 Leishmania major (virus) 35182 Monocosta brevicollis (choanoflagellate) ENSMODP00000013126 Monodelphis domestica (gray opossum) ENSMMUP00000036457 Macaca mulatta (rhesus monkey) ENSMUSP00000054452 Mus musculus (house mouse) ENSMUSP00000108855 Mus musculus (house mouse) 244739 Nematostella vectensis (starlet anemone) XP_001604409.1 Nasonia vitripennis (wasp) ENSOANP00000021601 Ornithorynchus anatinus (platypus) ENSORLP00000007848 Oryzias latipes (japanese killifish) LOC_Os03g38020.1 Oryza sativa (asian rice) PP04681 Pristionchus pacificus (nematode) 214279 Physcomitrella patens (moss) 221484 Physcomitrella patens (moss) ENSPPYP00000016542 Pongo pygmaeus (orangutan) 71513 Phytophthora ramorum (sudden oak death pathogen) 108781 Phytophthora sojae (root rot pathogen) 836365 Populus trichocarpa (black cottonwood) ENSPTRP00000027740 Pan troglodytes (chimpanzee) ENSRNOP00000014650 Rattus norvegicus (norway rat) 4890283 Sorghum bicolor (sorghum) YIL106W Saccharomyces cerevisiae (budding yeast) Smp_070610.2 Schistosoma mansoni (trematode parasite) SPBC428.13c Schizosaccharomyces pombe (fission yeast) XP_001179470.1 Strongylocentrotus purpuratus (purple sea urchin) 59290 Trichoplax adhaerens (metazoa) XP_971775.1 Tribolium castaneum (red flour beetle) Tc00.1047053510303.190 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000010293 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000025917 Takifugu rubripes (pufferfish Takifugu) 3673.m00043 Tetrahymena thermophila (ciliate protozoa) 92185.m00038 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000026404 Xenopus tropicalis (frog) ENSXETP00000051026 Xenopus tropicalis (frog) YALI0D08580g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17565 NV15091 LH16328 ISCW013173 FBgn0228171 FBgn0215083 FBgn0211498 FBgn0192406 FBgn0181285 JGI_V11_223739 FBgn0247915 FBgn0161805 FBgn0145113 FBgn0120864 FBgn0103436 FBgn0095466 CPIJ003355 BGIBMGA013463 ACYPI001756 GB15922 AGAP002066 AAEL010046 GLEAN_04387
Stocks & Reagents
Stocks Listed in FlyBase ( 7 )
Bloomington	32095 w*; P{UAS-mats.L}3a P{UAS-mats.L}3b 29567 y1 v1; P{TRiP.JF03246}attP2 34959 y1 sc* v1; P{TRiP.HMS00475}attP2 18115 w1118; PBac{RB}matse03077/TM6B, Tb1
Harvard	- PBac{RB}matse03077
VDRC	v108080 P{KK100140}VIE-260B v17716 w1118; P{GD8136}v17716
Genomic Clones ( 1 )
	BACR30J14 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 22 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD47553
Other clones	DPiM_LD47553
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT18877 GM07814 GM09547 LP03690 RE02151 RE15113
Other clones	28148 63283 122171 153990 155621 173922 280774 EK135759 EK160102 EK190123 EK196603 EK258549 EK259246 EK305543
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0038965 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42634
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: CG13852 mats (Lai et al., 2005)
Source for database merge of	Source for merge of: CG13852 anon-WO0118547.303 (FlyBase, 1996-)
Additional comments	Source for merge of CG13852 anon-WO0118547.303 was sequence comparison (date:051113). (FlyBase, 1996-)
Other Comments
	Area matching Drosophila EST AA201430. (Davies, 2001.3.15)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_142784 RefSeq (Proteins) • NP_651041 DDBJ / EMBL / GenBank • AA201430 AAF55993 AAL29068 AI515650 AW943919 AX094179 AY061520 CZ480841 CZ480842 CZ480844 Entrez Gene - A searchable database of RefSeq genes. • 42634 UniProtKB/TrEMBL • Q95RA8
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Mob1/phocein (IPR005301)
Linkouts
	BioGRID - A database of protein and genetic interactions • 67590 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0038965 DroID - A comprehensive database of gene and protein interactions. • FBgn0038965 DRSC - Results from RNAi screens. • FBgn0038965 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038965 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG13852-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0038965 FlyReactome - A curated knowledgebase of Drosophila melanogaster pathways • 237599 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42634 InParanoid A subset of ortholog calls from InParanoid. • AAEL010046-PB Aedes aegypti (mosquito) AGAP002066-PA Anopheles gambiae (mosquito) XP_393046.2 Apis mellifera (honey bee) XP_001949733.1 Acyrthosiphon pisum (pea aphid) At5g45550.1 Arabidopsis thaliana (wall cress) 30301 Batrachochytrium dendrobatidis (chytrid fungus) 131298 Branchiostoma floridae (lancelet) BGIBMGA013463-PA Bombyx mori (silk worm) ENSBTAP00000021671 Bos taurus (bovine) CAL0006122 Candida albicans (a form of yeast) ENSCAFP00000004332 Canis familiaris (dog) ENSCAFP00000012856 Canis familiaris (dog) CAGL0G02805g Candida glabrata (haploid yeast) ENSCINP00000006737 Ciona intestinalis (sea squirt) cn12194 Cryptococcus neoformans (yeast-like fungus) CPIJ003355 Culex pipens (mosquito) ENSCPOP00000010425 Cavia porcellus (guinea pig) 133994 Chlamidomonas reinhardtii (green alga) ENSCSAVP00000019672 Ciona savignyi (sedentary tunicate) 21709 Capitella spl (polychaete worm) DDB0232218 Dictyostelium discoideum (amoeba) DEHA2A06600g Debaryomyces Hansenii (yeast) 223739 Daphnia pulex (daphnia) ENSDARP00000088385 Danio rerio (zebra fish) ENSECAP00000021254 Equus caballus (horse) XP_650241 Entamoeba histolytica (anaerobic protozoan) XP_653257 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000011015 Gymnopilus aculeatus (mushroom) ENSGACP00000020943 Gymnopilus aculeatus (mushroom) ENSGALP00000018856 Gallus gallus (chicken) GL50803_11044 Giardia lamblia (flagellated protozoan) 185118 Hypsipyla robusta (cedar shoot borer) ENSP00000310189 Homo sapiens (human) ISCW013173-PA Ixodes scapularis (deer tick) KLLA0F03795g Kluyveromyces lactis (yeast) 238983 Lottia gigantea (owl limpet) LmjF06.0960 Leishmania major (virus) 35182 Monocosta brevicollis (choanoflagellate) ENSMODP00000013126 Monodelphis domestica (gray opossum) ENSMMUP00000036457 Macaca mulatta (rhesus monkey) ENSMUSP00000054452 Mus musculus (house mouse) ENSMUSP00000108855 Mus musculus (house mouse) 244739 Nematostella vectensis (starlet anemone) XP_001604409.1 Nasonia vitripennis (wasp) ENSOANP00000021601 Ornithorynchus anatinus (platypus) ENSORLP00000007848 Oryzias latipes (japanese killifish) LOC_Os03g38020.1 Oryza sativa (asian rice) PP04681 Pristionchus pacificus (nematode) 214279 Physcomitrella patens (moss) 221484 Physcomitrella patens (moss) ENSPPYP00000016542 Pongo pygmaeus (orangutan) 71513 Phytophthora ramorum (sudden oak death pathogen) 108781 Phytophthora sojae (root rot pathogen) 836365 Populus trichocarpa (black cottonwood) ENSPTRP00000027740 Pan troglodytes (chimpanzee) ENSRNOP00000014650 Rattus norvegicus (norway rat) 4890283 Sorghum bicolor (sorghum) YIL106W Saccharomyces cerevisiae (budding yeast) Smp_070610.2 Schistosoma mansoni (trematode parasite) SPBC428.13c Schizosaccharomyces pombe (fission yeast) XP_001179470.1 Strongylocentrotus purpuratus (purple sea urchin) 59290 Trichoplax adhaerens (metazoa) XP_971775.1 Tribolium castaneum (red flour beetle) Tc00.1047053510303.190 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000010293 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000025917 Takifugu rubripes (pufferfish Takifugu) 3673.m00043 Tetrahymena thermophila (ciliate protozoa) 92185.m00038 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000026404 Xenopus tropicalis (frog) ENSXETP00000051026 Xenopus tropicalis (frog) YALI0D08580g Yarrowia lipolytica (nonconventional yeast) Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /sturtevant/mob-mats1.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42634 modMine - Data generated by the modENCODE project. • FBgn0038965 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17565 NV15091 LH16328 ISCW013173 FBgn0228171 FBgn0215083 FBgn0211498 FBgn0192406 FBgn0181285 JGI_V11_223739 FBgn0247915 FBgn0161805 FBgn0145113 FBgn0120864 FBgn0103436 FBgn0095466 CPIJ003355 BGIBMGA013463 ACYPI001756 GB15922 AGAP002066 AAEL010046 GLEAN_04387
Synonyms & Secondary IDs ( 10 )
Reported As
Symbol Synonym	anon-WO0118547.303   CG13852 (Robertson, 2001.7.7, O'Farrell, 2001.9.11, Giot et al., 2003, Davies et al., 2001, He et al., 2005, Keleman et al., 2009.8.5, Perkins et al., 2009, Schulte et al., 2010, Ni et al., 2011.7.19) DMob1 (Domingues et al., 2005) dmob1 (Wainman et al., 2004) Dmob1 (He et al., 2005) mats (Tyler et al., 2007, Fang and Adler, 2007, Wei et al., 2007, Shimizu et al., 2008, Fernández et al., 2011, Truscott et al., 2011, He et al., 2005, Sun et al., 2008, Yang et al., 2008, Menut et al., 2007, Wei et al., 2007, Schuldiner et al., 2008, Oh and Irvine, 2008, Polesello and Tapon, 2007, Dutta and Baehrecke, 2008, Cho et al., 2006, Ho et al., 2010, Fang and Adler, 2010, Schulte et al., 2010, Kong et al., 2010, Rauskolb et al., 2011) Mats (Ren et al., 2010, Bateman and McNeill, 2005, Polesello et al., 2006, Hariharan, 2006) Mob1 (Schulte et al., 2010)
Name Synonym	mats (Xu and Bergmann, 2008) mob as tumor suppressor (Lai et al., 2005, Edgar, 2006, Shimizu et al., 2008, Sun et al., 2008, Yang et al., 2008, Cho et al., 2006, Mummery-Widmer et al., 2009) Mob as tumor suppressor (Colombani et al., 2006, Wei et al., 2007, Ho et al., 2010)
Secondary FlyBase IDs
	FBgn0062109
References ( 58 )
Generate a list of	All references relating to this gene ( 58 )
List References by type	Research paper  ( 26 ) Supplementary material  ( 3 ) Review  ( 4 ) Personal communication to FlyBase  ( 8 ) Abstract  ( 10 ) FlyBase analysis  ( 2 ) Patent  ( 1 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 3 )
Recent research papers ( 10 )
	Fernández et al., 2011, Development 138(11): 2337--2346 Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila. [FBrf0213674] Nicolay et al., 2011, Genes Dev. 25(4): 323--335 Cooperation between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exit. [FBrf0214348] Poon et al., 2011, Dev. Cell 21(5): 896--906 The Sterile 20-like Kinase Tao-1 Controls Tissue Growth by Regulating the Salvador-Warts-Hippo Pathway. [FBrf0216620] Rauskolb et al., 2011, PLoS Biol. 9(6): e1000624 Zyxin links fat signaling to the hippo pathway. [FBrf0213900] Truscott et al., 2011, Genes Dev. 25(17): 1820--1834 mir-11 limits the proapoptotic function of its host gene, dE2f1. [FBrf0215211] Fang and Adler, 2010, Dev. Biol. 341(2): 360--374 Regulation of cell shape, wing hair initiation and the actin cytoskeleton by Trc/Fry and Wts/Mats complexes. [FBrf0210701] Ho et al., 2010, Dev. Biol. 337(2): 274--283 Mob as tumor suppressor is activated at the cell membrane to control tissue growth and organ size in Drosophila. [FBrf0209794] Kong et al., 2010, Alcoholism, Clin. Exp. Res. 34(2): 302--316 Ethanol-regulated genes that contribute to ethanol sensitivity and rapid tolerance in Drosophila. [FBrf0209720] Ren et al., 2010, Dev. Biol. 337(2): 303--312 Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms. [FBrf0209792] Schulte et al., 2010, J. Neurosci. 30(15): 5189--5203 DMob4/Phocein regulates synapse formation, axonal transport, and microtubule organization. [FBrf0210612] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...