General Information Symbol Dmel\ CG5315Species D. melanogaster Name Annotation symbol CG5315 Feature type protein_coding_gene FlyBase ID FBgn0038984 Gene Model Status Current Stock availability 5 publicly
available Genomic Location Chromosome (arm) 3R Recombination map Cytogenetic map 94B3-94B3 Sequence location 3R:18,369,415..18,373,568 [-]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information This gene is referred to in FlyBase by the symbol
Dmel\CG5315 (FBgn0038984). It is a protein_coding_gene from
Drosophila melanogaster . Based on sequence similarity, it is predicted to have
molecular function : hormone binding. Based on sequence similarity, it is predicted to be involved in the
biological process : hormone-mediated signaling pathway; fatty acid oxidation.
5 alleles are reported . No phenotypic data is available. It has
5 annotated transcripts and
5 annotated polypeptides .
Protein features are: Hly-III-related. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult midgut, adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, adult salivary gland, adult spermathecae, adult male accessory gland, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval hindgut, larval salivary gland, larval trachea, adult ovary, adult testis, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1636967_a_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of CG5315. Gene sequence location is
3R:18369415..18373568 .
User Contributed Data
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FB2013_03
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.40
Gene model reviewed during 5.47
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: maternally deposited
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
414.475
Larval Midgut
642.7
Larval Hindgut
427.6
Larval Malpighian Tubules
674
Larval Fat Body
702
Larval Salivary Gland
386.3
Larval Trachea
438.65
Larval Carcass
272.975
Adult Head
2183.5
Adult Eye
2811.925
Adult Brain
1021.9
Adult Thoracic-Abdominal Ganglion
1139.6
Adult Crop
2719.1
Adult Midgut
957.5
Adult Hindgut
1990.9
Adult Malpighian Tubules
551
Adult Fat Body
3572.2
Adult Salivary Gland
1225.3
Adult Heart
3391.8
Adult VirginFemale Spermatheca
4414.2
Adult InseminatedFemale Spermatheca
3933.4
Adult Ovary
134.8
Adult Testis
107.8
Adult Male Accessory Gland
1042.6
Adult Carcass
2573.9
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
414.475
Larval Midgut
(642.7)
Larval Hindgut
427.6
Larval Malpighian Tubules
(674)
Larval Fat Body
(702)
Larval Salivary Gland
386.3
Larval Trachea
438.65
Larval Carcass
272.975
Adult Head
(2183.5)
Adult Eye
(2811.925)
Adult Brain
(1021.9)
Adult Thoracic-Abdominal Ganglion
(1139.6)
Adult Crop
(2719.1)
Adult Midgut
(957.5)
Adult Hindgut
(1990.9)
Adult Malpighian Tubules
(551)
Adult Fat Body
(3572.2)
Adult Salivary Gland
(1225.3)
Adult Heart
(3391.8)
Adult VirginFemale Spermatheca
(4414.2)
Adult InseminatedFemale Spermatheca
(3933.4)
Adult Ovary
134.8
Adult Testis
107.8
Adult Male Accessory Gland
(1042.6)
Adult Carcass
(2573.9)
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
414.475
Larval Midgut
642.7
Larval Hindgut
427.6
Larval Malpighian Tubules
674
Larval Fat Body
702
Larval Salivary Gland
386.3
Larval Trachea
438.65
Larval Carcass
272.975
Adult Head
(2183.5)
Adult Eye
(2811.925)
Adult Brain
1021.9
Adult Thoracic-Abdominal Ganglion
(1139.6)
Adult Crop
(2719.1)
Adult Midgut
957.5
Adult Hindgut
(1990.9)
Adult Malpighian Tubules
551
Adult Fat Body
(3572.2)
Adult Salivary Gland
(1225.3)
Adult Heart
(3391.8)
Adult VirginFemale Spermatheca
(4414.2)
Adult InseminatedFemale Spermatheca
(3933.4)
Adult Ovary
134.8
Adult Testis
107.8
Adult Male Accessory Gland
1042.6
Adult Carcass
(2573.9)
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
414.475
Larval Midgut
642.7
Larval Hindgut
427.6
Larval Malpighian Tubules
674
Larval Fat Body
702
Larval Salivary Gland
386.3
Larval Trachea
438.65
Larval Carcass
272.975
Adult Head
2183.5
Adult Eye
2811.925
Adult Brain
1021.9
Adult Thoracic-Abdominal Ganglion
1139.6
Adult Crop
2719.1
Adult Midgut
957.5
Adult Hindgut
1990.9
Adult Malpighian Tubules
551
Adult Fat Body
3572.2
Adult Salivary Gland
1225.3
Adult Heart
3391.8
Adult VirginFemale Spermatheca
4414.2
Adult InseminatedFemale Spermatheca
3933.4
Adult Ovary
134.8
Adult Testis
107.8
Adult Male Accessory Gland
1042.6
Adult Carcass
2573.9
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
414.475
Larval Midgut
642.7
Larval Hindgut
427.6
Larval Malpighian Tubules
674
Larval Fat Body
702
Larval Salivary Gland
386.3
Larval Trachea
438.65
Larval Carcass
272.975
Adult Head
2183.5
Adult Eye
2811.925
Adult Brain
1021.9
Adult Thoracic-Abdominal Ganglion
1139.6
Adult Crop
2719.1
Adult Midgut
957.5
Adult Hindgut
1990.9
Adult Malpighian Tubules
551
Adult Fat Body
3572.2
Adult Salivary Gland
1225.3
Adult Heart
3391.8
Adult VirginFemale Spermatheca
4414.2
Adult InseminatedFemale Spermatheca
3933.4
Adult Ovary
134.8
Adult Testis
107.8
Adult Male Accessory Gland
1042.6
Adult Carcass
2573.9
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
414.475
Larval Midgut
642.7
Larval Hindgut
427.6
Larval Malpighian Tubules
674
Larval Fat Body
702
Larval Salivary Gland
386.3
Larval Trachea
438.65
Larval Carcass
272.975
Adult Head
(2183.5)
Adult Eye
(2811.925)
Adult Brain
(1021.9)
Adult Thoracic-Abdominal Ganglion
(1139.6)
Adult Crop
(2719.1)
Adult Midgut
(957.5)
Adult Hindgut
(1990.9)
Adult Malpighian Tubules
551
Adult Fat Body
(3572.2)
Adult Salivary Gland
(1225.3)
Adult Heart
(3391.8)
Adult VirginFemale Spermatheca
(4414.2)
Adult InseminatedFemale Spermatheca
(3933.4)
Adult Ovary
134.8
Adult Testis
107.8
Adult Male Accessory Gland
(1042.6)
Adult Carcass
(2573.9)
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
414.475
Larval Midgut
642.7
Larval Hindgut
427.6
Larval Malpighian Tubules
674
Larval Fat Body
702
Larval Salivary Gland
386.3
Larval Trachea
438.65
Larval Carcass
272.975
Adult Head
(2183.5)
Adult Eye
(2811.925)
Adult Brain
1021.9
Adult Thoracic-Abdominal Ganglion
1139.6
Adult Crop
(2719.1)
Adult Midgut
957.5
Adult Hindgut
(1990.9)
Adult Malpighian Tubules
551
Adult Fat Body
(3572.2)
Adult Salivary Gland
1225.3
Adult Heart
(3391.8)
Adult VirginFemale Spermatheca
(4414.2)
Adult InseminatedFemale Spermatheca
(3933.4)
Adult Ovary
134.8
Adult Testis
107.8
Adult Male Accessory Gland
1042.6
Adult Carcass
(2573.9)
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
414.475
Larval Midgut
642.7
Larval Hindgut
427.6
Larval Malpighian Tubules
674
Larval Fat Body
702
Larval Salivary Gland
386.3
Larval Trachea
438.65
Larval Carcass
272.975
Adult Head
2183.5
Adult Eye
2811.925
Adult Brain
1021.9
Adult Thoracic-Abdominal Ganglion
1139.6
Adult Crop
2719.1
Adult Midgut
957.5
Adult Hindgut
1990.9
Adult Malpighian Tubules
551
Adult Fat Body
3572.2
Adult Salivary Gland
1225.3
Adult Heart
3391.8
Adult VirginFemale Spermatheca
4414.2
Adult InseminatedFemale Spermatheca
3933.4
Adult Ovary
134.8
Adult Testis
107.8
Adult Male Accessory Gland
1042.6
Adult Carcass
2573.9
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
2183.5
NA
Eye
2811.925
NA
Brain
1021.9
414.475
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
1139.6
NA
Crop
2719.1
642.7
Midgut
957.5
427.6
Hindgut
1990.9
674
Malpighian Tubules
551
702
Fat Body
3572.2
386.3
Salivary Gland
1225.3
NA
Heart
3391.8
438.65
Trachea
NA
NA
VirginFemale Spermatheca
4414.2
NA
InseminatedFemale Spermatheca
3933.4
NA
Ovary
134.8
NA
Testis
107.8
NA
Male Accessory Gland
1042.6
272.975
Carcass
2573.9
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
49
central nervous system, larvae L3
22
central nervous system, pupae P8
54
head, virgin 1-day female
90
head, virgin 4-day female
129
head, virgin 20-day female
190
head, mated 1-day female
84
head, mated 4-day female
133
head, mated 20-day female
133
head, mated 1-day male
104
head, mated 4-day male
131
head, mated 20-day male
147
salivary gland, larvae L3 wandering
13
salivary gland, white prepupae
27
digestive system, larvae L3 wandering
52
digestive system, 1-day adult
55
digestive system, 4-day adult
54
digestive system, 20-day adult
46
fat body, larvae L3 wandering
27
fat body, white prepupae
27
fat body, pupae P8
52
carcass, larvae L3 wandering
22
carcass, 1-day adult
80
carcass, 4-day adult
102
carcass, 20-day adult
130
ovary, virgin 4-day female
39
ovary, mated 4-day female
26
testis, mated 4-day male
86
accessory gland, mated 4-day male
46
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(49)
central nervous system, larvae L3
22
central nervous system, pupae P8
(54)
head, virgin 1-day female
(90)
head, virgin 4-day female
(129)
head, virgin 20-day female
(190)
head, mated 1-day female
(84)
head, mated 4-day female
(133)
head, mated 20-day female
(133)
head, mated 1-day male
(104)
head, mated 4-day male
(131)
head, mated 20-day male
(147)
salivary gland, larvae L3 wandering
13
salivary gland, white prepupae
(27)
digestive system, larvae L3 wandering
(52)
digestive system, 1-day adult
(55)
digestive system, 4-day adult
(54)
digestive system, 20-day adult
(46)
fat body, larvae L3 wandering
(27)
fat body, white prepupae
(27)
fat body, pupae P8
(52)
carcass, larvae L3 wandering
22
carcass, 1-day adult
(80)
carcass, 4-day adult
(102)
carcass, 20-day adult
(130)
ovary, virgin 4-day female
(39)
ovary, mated 4-day female
26
testis, mated 4-day male
(86)
accessory gland, mated 4-day male
(46)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
49
central nervous system, larvae L3
22
central nervous system, pupae P8
54
head, virgin 1-day female
90
head, virgin 4-day female
(129)
head, virgin 20-day female
(190)
head, mated 1-day female
84
head, mated 4-day female
(133)
head, mated 20-day female
(133)
head, mated 1-day male
104
head, mated 4-day male
(131)
head, mated 20-day male
(147)
salivary gland, larvae L3 wandering
13
salivary gland, white prepupae
27
digestive system, larvae L3 wandering
52
digestive system, 1-day adult
55
digestive system, 4-day adult
54
digestive system, 20-day adult
46
fat body, larvae L3 wandering
27
fat body, white prepupae
27
fat body, pupae P8
52
carcass, larvae L3 wandering
22
carcass, 1-day adult
80
carcass, 4-day adult
102
carcass, 20-day adult
(130)
ovary, virgin 4-day female
39
ovary, mated 4-day female
26
testis, mated 4-day male
86
accessory gland, mated 4-day male
46
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
49
central nervous system, larvae L3
22
central nervous system, pupae P8
54
head, virgin 1-day female
90
head, virgin 4-day female
129
head, virgin 20-day female
190
head, mated 1-day female
84
head, mated 4-day female
133
head, mated 20-day female
133
head, mated 1-day male
104
head, mated 4-day male
131
head, mated 20-day male
147
salivary gland, larvae L3 wandering
13
salivary gland, white prepupae
27
digestive system, larvae L3 wandering
52
digestive system, 1-day adult
55
digestive system, 4-day adult
54
digestive system, 20-day adult
46
fat body, larvae L3 wandering
27
fat body, white prepupae
27
fat body, pupae P8
52
carcass, larvae L3 wandering
22
carcass, 1-day adult
80
carcass, 4-day adult
102
carcass, 20-day adult
130
ovary, virgin 4-day female
39
ovary, mated 4-day female
26
testis, mated 4-day male
86
accessory gland, mated 4-day male
46
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
49
central nervous system, larvae L3
22
central nervous system, pupae P8
54
head, virgin 1-day female
90
head, virgin 4-day female
129
head, virgin 20-day female
190
head, mated 1-day female
84
head, mated 4-day female
133
head, mated 20-day female
133
head, mated 1-day male
104
head, mated 4-day male
131
head, mated 20-day male
147
salivary gland, larvae L3 wandering
13
salivary gland, white prepupae
27
digestive system, larvae L3 wandering
52
digestive system, 1-day adult
55
digestive system, 4-day adult
54
digestive system, 20-day adult
46
fat body, larvae L3 wandering
27
fat body, white prepupae
27
fat body, pupae P8
52
carcass, larvae L3 wandering
22
carcass, 1-day adult
80
carcass, 4-day adult
102
carcass, 20-day adult
130
ovary, virgin 4-day female
39
ovary, mated 4-day female
26
testis, mated 4-day male
86
accessory gland, mated 4-day male
46
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(49)
central nervous system, larvae L3
22
central nervous system, pupae P8
(54)
head, virgin 1-day female
(90)
head, virgin 4-day female
(129)
head, virgin 20-day female
(190)
head, mated 1-day female
(84)
head, mated 4-day female
(133)
head, mated 20-day female
(133)
head, mated 1-day male
(104)
head, mated 4-day male
(131)
head, mated 20-day male
(147)
salivary gland, larvae L3 wandering
13
salivary gland, white prepupae
27
digestive system, larvae L3 wandering
(52)
digestive system, 1-day adult
(55)
digestive system, 4-day adult
(54)
digestive system, 20-day adult
(46)
fat body, larvae L3 wandering
27
fat body, white prepupae
27
fat body, pupae P8
(52)
carcass, larvae L3 wandering
22
carcass, 1-day adult
(80)
carcass, 4-day adult
(102)
carcass, 20-day adult
(130)
ovary, virgin 4-day female
(39)
ovary, mated 4-day female
26
testis, mated 4-day male
(86)
accessory gland, mated 4-day male
(46)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
49
central nervous system, larvae L3
22
central nervous system, pupae P8
54
head, virgin 1-day female
90
head, virgin 4-day female
129
head, virgin 20-day female
(190)
head, mated 1-day female
84
head, mated 4-day female
133
head, mated 20-day female
133
head, mated 1-day male
104
head, mated 4-day male
131
head, mated 20-day male
(147)
salivary gland, larvae L3 wandering
13
salivary gland, white prepupae
27
digestive system, larvae L3 wandering
52
digestive system, 1-day adult
55
digestive system, 4-day adult
54
digestive system, 20-day adult
46
fat body, larvae L3 wandering
27
fat body, white prepupae
27
fat body, pupae P8
52
carcass, larvae L3 wandering
22
carcass, 1-day adult
80
carcass, 4-day adult
102
carcass, 20-day adult
130
ovary, virgin 4-day female
39
ovary, mated 4-day female
26
testis, mated 4-day male
86
accessory gland, mated 4-day male
46
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
49
central nervous system, larvae L3
22
central nervous system, pupae P8
54
head, virgin 1-day female
90
head, virgin 4-day female
129
head, virgin 20-day female
190
head, mated 1-day female
84
head, mated 4-day female
133
head, mated 20-day female
133
head, mated 1-day male
104
head, mated 4-day male
131
head, mated 20-day male
147
salivary gland, larvae L3 wandering
13
salivary gland, white prepupae
27
digestive system, larvae L3 wandering
52
digestive system, 1-day adult
55
digestive system, 4-day adult
54
digestive system, 20-day adult
46
fat body, larvae L3 wandering
27
fat body, white prepupae
27
fat body, pupae P8
52
carcass, larvae L3 wandering
22
carcass, 1-day adult
80
carcass, 4-day adult
102
carcass, 20-day adult
130
ovary, virgin 4-day female
39
ovary, mated 4-day female
26
testis, mated 4-day male
86
accessory gland, mated 4-day male
46
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
50
embryo 02-04hr
38
embryo 04-06hr
69
embryo 06-08hr
76
embryo 08-10hr
77
embryo 10-12hr
101
embryo 12-14hr
80
embryo 14-16hr
66
embryo 16-18hr
65
embryo 18-20hr
54
embryo 20-22hr
33
embryo 22-24hr
42
larva L1
34
larva L2
41
larva L3 12hr old
41
larva L3 puffstage 1-2
36
larva L3 puffstage 3-6
49
larva L3 puffstage 7-9
60
white prepupae new
67
white prepupae 12hr
64
white prepupae 24hr
49
pupae 2d postWPP
70
pupae 3d postWPP
58
pupae 4d postWPP
50
adult male 01day
104
adult male 05day
106
adult male 30day
86
adult female 01day
61
adult female 05day
68
adult female 30day
63
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(50)
embryo 02-04hr
(38)
embryo 04-06hr
(69)
embryo 06-08hr
(76)
embryo 08-10hr
(77)
embryo 10-12hr
(101)
embryo 12-14hr
(80)
embryo 14-16hr
(66)
embryo 16-18hr
(65)
embryo 18-20hr
(54)
embryo 20-22hr
(33)
embryo 22-24hr
(42)
larva L1
(34)
larva L2
(41)
larva L3 12hr old
(41)
larva L3 puffstage 1-2
(36)
larva L3 puffstage 3-6
(49)
larva L3 puffstage 7-9
(60)
white prepupae new
(67)
white prepupae 12hr
(64)
white prepupae 24hr
(49)
pupae 2d postWPP
(70)
pupae 3d postWPP
(58)
pupae 4d postWPP
(50)
adult male 01day
(104)
adult male 05day
(106)
adult male 30day
(86)
adult female 01day
(61)
adult female 05day
(68)
adult female 30day
(63)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
50
embryo 02-04hr
38
embryo 04-06hr
69
embryo 06-08hr
76
embryo 08-10hr
77
embryo 10-12hr
101
embryo 12-14hr
80
embryo 14-16hr
66
embryo 16-18hr
65
embryo 18-20hr
54
embryo 20-22hr
33
embryo 22-24hr
42
larva L1
34
larva L2
41
larva L3 12hr old
41
larva L3 puffstage 1-2
36
larva L3 puffstage 3-6
49
larva L3 puffstage 7-9
60
white prepupae new
67
white prepupae 12hr
64
white prepupae 24hr
49
pupae 2d postWPP
70
pupae 3d postWPP
58
pupae 4d postWPP
50
adult male 01day
104
adult male 05day
106
adult male 30day
86
adult female 01day
61
adult female 05day
68
adult female 30day
63
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
50
embryo 02-04hr
38
embryo 04-06hr
69
embryo 06-08hr
76
embryo 08-10hr
77
embryo 10-12hr
101
embryo 12-14hr
80
embryo 14-16hr
66
embryo 16-18hr
65
embryo 18-20hr
54
embryo 20-22hr
33
embryo 22-24hr
42
larva L1
34
larva L2
41
larva L3 12hr old
41
larva L3 puffstage 1-2
36
larva L3 puffstage 3-6
49
larva L3 puffstage 7-9
60
white prepupae new
67
white prepupae 12hr
64
white prepupae 24hr
49
pupae 2d postWPP
70
pupae 3d postWPP
58
pupae 4d postWPP
50
adult male 01day
104
adult male 05day
106
adult male 30day
86
adult female 01day
61
adult female 05day
68
adult female 30day
63
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
50
embryo 02-04hr
38
embryo 04-06hr
69
embryo 06-08hr
76
embryo 08-10hr
77
embryo 10-12hr
101
embryo 12-14hr
80
embryo 14-16hr
66
embryo 16-18hr
65
embryo 18-20hr
54
embryo 20-22hr
33
embryo 22-24hr
42
larva L1
34
larva L2
41
larva L3 12hr old
41
larva L3 puffstage 1-2
36
larva L3 puffstage 3-6
49
larva L3 puffstage 7-9
60
white prepupae new
67
white prepupae 12hr
64
white prepupae 24hr
49
pupae 2d postWPP
70
pupae 3d postWPP
58
pupae 4d postWPP
50
adult male 01day
104
adult male 05day
106
adult male 30day
86
adult female 01day
61
adult female 05day
68
adult female 30day
63
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(50)
embryo 02-04hr
(38)
embryo 04-06hr
(69)
embryo 06-08hr
(76)
embryo 08-10hr
(77)
embryo 10-12hr
(101)
embryo 12-14hr
(80)
embryo 14-16hr
(66)
embryo 16-18hr
(65)
embryo 18-20hr
(54)
embryo 20-22hr
(33)
embryo 22-24hr
(42)
larva L1
(34)
larva L2
(41)
larva L3 12hr old
(41)
larva L3 puffstage 1-2
(36)
larva L3 puffstage 3-6
(49)
larva L3 puffstage 7-9
(60)
white prepupae new
(67)
white prepupae 12hr
(64)
white prepupae 24hr
(49)
pupae 2d postWPP
(70)
pupae 3d postWPP
(58)
pupae 4d postWPP
(50)
adult male 01day
(104)
adult male 05day
(106)
adult male 30day
(86)
adult female 01day
(61)
adult female 05day
(68)
adult female 30day
(63)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
50
embryo 02-04hr
38
embryo 04-06hr
69
embryo 06-08hr
76
embryo 08-10hr
77
embryo 10-12hr
101
embryo 12-14hr
80
embryo 14-16hr
66
embryo 16-18hr
65
embryo 18-20hr
54
embryo 20-22hr
33
embryo 22-24hr
42
larva L1
34
larva L2
41
larva L3 12hr old
41
larva L3 puffstage 1-2
36
larva L3 puffstage 3-6
49
larva L3 puffstage 7-9
60
white prepupae new
67
white prepupae 12hr
64
white prepupae 24hr
49
pupae 2d postWPP
70
pupae 3d postWPP
58
pupae 4d postWPP
50
adult male 01day
104
adult male 05day
106
adult male 30day
86
adult female 01day
61
adult female 05day
68
adult female 30day
63
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
50
embryo 02-04hr
38
embryo 04-06hr
69
embryo 06-08hr
76
embryo 08-10hr
77
embryo 10-12hr
101
embryo 12-14hr
80
embryo 14-16hr
66
embryo 16-18hr
65
embryo 18-20hr
54
embryo 20-22hr
33
embryo 22-24hr
42
larva L1
34
larva L2
41
larva L3 12hr old
41
larva L3 puffstage 1-2
36
larva L3 puffstage 3-6
49
larva L3 puffstage 7-9
60
white prepupae new
67
white prepupae 12hr
64
white prepupae 24hr
49
pupae 2d postWPP
70
pupae 3d postWPP
58
pupae 4d postWPP
50
adult male 01day
104
adult male 05day
106
adult male 30day
86
adult female 01day
61
adult female 05day
68
adult female 30day
63
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
103
Schneider line 2 Sg4
56
embryonic 1182-4H
24
embryonic GM2
64
embryonic Kc167
57
embryonic S1
29
embryonic S3
70
leg disc CME L1
36
wing disc CME-W2
68
wing disc ML-DmD8
29
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
29
wing disc ML-DmD21
30
wing disc ML-DmD32
22
haltere disc ML-DmD17-c3
34
eye-antennal disc ML-DmD11
26
antennal disc ML-DmD20-c5
40
mixed discs ML-DmD4-c1
43
CNS ML-DmBG1-c1
29
CNS ML-DmBG2-c2
49
tumorous blood cells mbn2
54
ovary fGS/OSS
22
ovary OSC
17
ovary OSS
13
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(103)
Schneider line 2 Sg4
(56)
embryonic 1182-4H
24
embryonic GM2
(64)
embryonic Kc167
(57)
embryonic S1
(29)
embryonic S3
(70)
leg disc CME L1
(36)
wing disc CME-W2
(68)
wing disc ML-DmD8
(29)
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
(29)
wing disc ML-DmD21
(30)
wing disc ML-DmD32
22
haltere disc ML-DmD17-c3
(34)
eye-antennal disc ML-DmD11
26
antennal disc ML-DmD20-c5
(40)
mixed discs ML-DmD4-c1
(43)
CNS ML-DmBG1-c1
(29)
CNS ML-DmBG2-c2
(49)
tumorous blood cells mbn2
(54)
ovary fGS/OSS
22
ovary OSC
17
ovary OSS
13
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
103
Schneider line 2 Sg4
56
embryonic 1182-4H
24
embryonic GM2
64
embryonic Kc167
57
embryonic S1
29
embryonic S3
70
leg disc CME L1
36
wing disc CME-W2
68
wing disc ML-DmD8
29
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
29
wing disc ML-DmD21
30
wing disc ML-DmD32
22
haltere disc ML-DmD17-c3
34
eye-antennal disc ML-DmD11
26
antennal disc ML-DmD20-c5
40
mixed discs ML-DmD4-c1
43
CNS ML-DmBG1-c1
29
CNS ML-DmBG2-c2
49
tumorous blood cells mbn2
54
ovary fGS/OSS
22
ovary OSC
17
ovary OSS
13
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
103
Schneider line 2 Sg4
56
embryonic 1182-4H
24
embryonic GM2
64
embryonic Kc167
57
embryonic S1
29
embryonic S3
70
leg disc CME L1
36
wing disc CME-W2
68
wing disc ML-DmD8
29
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
29
wing disc ML-DmD21
30
wing disc ML-DmD32
22
haltere disc ML-DmD17-c3
34
eye-antennal disc ML-DmD11
26
antennal disc ML-DmD20-c5
40
mixed discs ML-DmD4-c1
43
CNS ML-DmBG1-c1
29
CNS ML-DmBG2-c2
49
tumorous blood cells mbn2
54
ovary fGS/OSS
22
ovary OSC
17
ovary OSS
13
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
103
Schneider line 2 Sg4
56
embryonic 1182-4H
24
embryonic GM2
64
embryonic Kc167
57
embryonic S1
29
embryonic S3
70
leg disc CME L1
36
wing disc CME-W2
68
wing disc ML-DmD8
29
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
29
wing disc ML-DmD21
30
wing disc ML-DmD32
22
haltere disc ML-DmD17-c3
34
eye-antennal disc ML-DmD11
26
antennal disc ML-DmD20-c5
40
mixed discs ML-DmD4-c1
43
CNS ML-DmBG1-c1
29
CNS ML-DmBG2-c2
49
tumorous blood cells mbn2
54
ovary fGS/OSS
22
ovary OSC
17
ovary OSS
13
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(103)
Schneider line 2 Sg4
(56)
embryonic 1182-4H
24
embryonic GM2
(64)
embryonic Kc167
(57)
embryonic S1
29
embryonic S3
(70)
leg disc CME L1
(36)
wing disc CME-W2
(68)
wing disc ML-DmD8
29
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
29
wing disc ML-DmD21
30
wing disc ML-DmD32
22
haltere disc ML-DmD17-c3
(34)
eye-antennal disc ML-DmD11
26
antennal disc ML-DmD20-c5
(40)
mixed discs ML-DmD4-c1
(43)
CNS ML-DmBG1-c1
29
CNS ML-DmBG2-c2
(49)
tumorous blood cells mbn2
(54)
ovary fGS/OSS
22
ovary OSC
17
ovary OSS
13
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
103
Schneider line 2 Sg4
56
embryonic 1182-4H
24
embryonic GM2
64
embryonic Kc167
57
embryonic S1
29
embryonic S3
70
leg disc CME L1
36
wing disc CME-W2
68
wing disc ML-DmD8
29
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
29
wing disc ML-DmD21
30
wing disc ML-DmD32
22
haltere disc ML-DmD17-c3
34
eye-antennal disc ML-DmD11
26
antennal disc ML-DmD20-c5
40
mixed discs ML-DmD4-c1
43
CNS ML-DmBG1-c1
29
CNS ML-DmBG2-c2
49
tumorous blood cells mbn2
54
ovary fGS/OSS
22
ovary OSC
17
ovary OSS
13
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
103
Schneider line 2 Sg4
56
embryonic 1182-4H
24
embryonic GM2
64
embryonic Kc167
57
embryonic S1
29
embryonic S3
70
leg disc CME L1
36
wing disc CME-W2
68
wing disc ML-DmD8
29
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
29
wing disc ML-DmD21
30
wing disc ML-DmD32
22
haltere disc ML-DmD17-c3
34
eye-antennal disc ML-DmD11
26
antennal disc ML-DmD20-c5
40
mixed discs ML-DmD4-c1
43
CNS ML-DmBG1-c1
29
CNS ML-DmBG2-c2
49
tumorous blood cells mbn2
54
ovary fGS/OSS
22
ovary OSC
17
ovary OSS
13
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
19
cold shock, 4-day adult
12
heat shock, 4-day adult
37
Cadmium 50 mM 6 hrs, larvae L3
32
Cadmium 50 mM 12 hrs, larvae L3
49
Cadmium 50 mM 48 hrs, 4-day adult
39
Cadmium 100 mM 48 hrs, 4-day adult
57
Copper 0.5 mM 12 hrs, larvae L3
13
Copper 15 mM 48 hrs, 4-day adult
98
Zinc 5 mM 12 hrs, larvae L3
11
Zinc 4.5 mM 48 hrs, 4-day adult
91
Ethanol 2.5% 3 hrs, larvae L3
54
Ethanol 5% 3 hrs, larvae L3
45
Ethanol 10% 3 hrs, larvae L3
31
Caffeine 1.5 mg/ml 4 hrs, larvae L3
38
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
75
Caffeine 25 mg/ml 48 hrs, 4-day adult
24
Paraquat 5 mM 48 hrs, 4-day adult
77
Paraquat 10 mM 48 hrs, 4-day adult
66
Rotenone 2 μg 12 hrs, larvae L3
43
Rotenone 8 μg 12 hrs, larvae L3
29
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
19
cold shock, 4-day adult
12
heat shock, 4-day adult
(37)
Cadmium 50 mM 6 hrs, larvae L3
(32)
Cadmium 50 mM 12 hrs, larvae L3
(49)
Cadmium 50 mM 48 hrs, 4-day adult
(39)
Cadmium 100 mM 48 hrs, 4-day adult
(57)
Copper 0.5 mM 12 hrs, larvae L3
13
Copper 15 mM 48 hrs, 4-day adult
(98)
Zinc 5 mM 12 hrs, larvae L3
11
Zinc 4.5 mM 48 hrs, 4-day adult
(91)
Ethanol 2.5% 3 hrs, larvae L3
(54)
Ethanol 5% 3 hrs, larvae L3
(45)
Ethanol 10% 3 hrs, larvae L3
(31)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(38)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(75)
Caffeine 25 mg/ml 48 hrs, 4-day adult
24
Paraquat 5 mM 48 hrs, 4-day adult
(77)
Paraquat 10 mM 48 hrs, 4-day adult
(66)
Rotenone 2 μg 12 hrs, larvae L3
(43)
Rotenone 8 μg 12 hrs, larvae L3
(29)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
19
cold shock, 4-day adult
12
heat shock, 4-day adult
37
Cadmium 50 mM 6 hrs, larvae L3
32
Cadmium 50 mM 12 hrs, larvae L3
49
Cadmium 50 mM 48 hrs, 4-day adult
39
Cadmium 100 mM 48 hrs, 4-day adult
57
Copper 0.5 mM 12 hrs, larvae L3
13
Copper 15 mM 48 hrs, 4-day adult
98
Zinc 5 mM 12 hrs, larvae L3
11
Zinc 4.5 mM 48 hrs, 4-day adult
91
Ethanol 2.5% 3 hrs, larvae L3
54
Ethanol 5% 3 hrs, larvae L3
45
Ethanol 10% 3 hrs, larvae L3
31
Caffeine 1.5 mg/ml 4 hrs, larvae L3
38
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
75
Caffeine 25 mg/ml 48 hrs, 4-day adult
24
Paraquat 5 mM 48 hrs, 4-day adult
77
Paraquat 10 mM 48 hrs, 4-day adult
66
Rotenone 2 μg 12 hrs, larvae L3
43
Rotenone 8 μg 12 hrs, larvae L3
29
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
19
cold shock, 4-day adult
12
heat shock, 4-day adult
37
Cadmium 50 mM 6 hrs, larvae L3
32
Cadmium 50 mM 12 hrs, larvae L3
49
Cadmium 50 mM 48 hrs, 4-day adult
39
Cadmium 100 mM 48 hrs, 4-day adult
57
Copper 0.5 mM 12 hrs, larvae L3
13
Copper 15 mM 48 hrs, 4-day adult
98
Zinc 5 mM 12 hrs, larvae L3
11
Zinc 4.5 mM 48 hrs, 4-day adult
91
Ethanol 2.5% 3 hrs, larvae L3
54
Ethanol 5% 3 hrs, larvae L3
45
Ethanol 10% 3 hrs, larvae L3
31
Caffeine 1.5 mg/ml 4 hrs, larvae L3
38
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
75
Caffeine 25 mg/ml 48 hrs, 4-day adult
24
Paraquat 5 mM 48 hrs, 4-day adult
77
Paraquat 10 mM 48 hrs, 4-day adult
66
Rotenone 2 μg 12 hrs, larvae L3
43
Rotenone 8 μg 12 hrs, larvae L3
29
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
19
cold shock, 4-day adult
12
heat shock, 4-day adult
37
Cadmium 50 mM 6 hrs, larvae L3
32
Cadmium 50 mM 12 hrs, larvae L3
49
Cadmium 50 mM 48 hrs, 4-day adult
39
Cadmium 100 mM 48 hrs, 4-day adult
57
Copper 0.5 mM 12 hrs, larvae L3
13
Copper 15 mM 48 hrs, 4-day adult
98
Zinc 5 mM 12 hrs, larvae L3
11
Zinc 4.5 mM 48 hrs, 4-day adult
91
Ethanol 2.5% 3 hrs, larvae L3
54
Ethanol 5% 3 hrs, larvae L3
45
Ethanol 10% 3 hrs, larvae L3
31
Caffeine 1.5 mg/ml 4 hrs, larvae L3
38
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
75
Caffeine 25 mg/ml 48 hrs, 4-day adult
24
Paraquat 5 mM 48 hrs, 4-day adult
77
Paraquat 10 mM 48 hrs, 4-day adult
66
Rotenone 2 μg 12 hrs, larvae L3
43
Rotenone 8 μg 12 hrs, larvae L3
29
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
19
cold shock, 4-day adult
12
heat shock, 4-day adult
(37)
Cadmium 50 mM 6 hrs, larvae L3
32
Cadmium 50 mM 12 hrs, larvae L3
(49)
Cadmium 50 mM 48 hrs, 4-day adult
(39)
Cadmium 100 mM 48 hrs, 4-day adult
(57)
Copper 0.5 mM 12 hrs, larvae L3
13
Copper 15 mM 48 hrs, 4-day adult
(98)
Zinc 5 mM 12 hrs, larvae L3
11
Zinc 4.5 mM 48 hrs, 4-day adult
(91)
Ethanol 2.5% 3 hrs, larvae L3
(54)
Ethanol 5% 3 hrs, larvae L3
(45)
Ethanol 10% 3 hrs, larvae L3
31
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(38)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(75)
Caffeine 25 mg/ml 48 hrs, 4-day adult
24
Paraquat 5 mM 48 hrs, 4-day adult
(77)
Paraquat 10 mM 48 hrs, 4-day adult
(66)
Rotenone 2 μg 12 hrs, larvae L3
(43)
Rotenone 8 μg 12 hrs, larvae L3
29
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
19
cold shock, 4-day adult
12
heat shock, 4-day adult
37
Cadmium 50 mM 6 hrs, larvae L3
32
Cadmium 50 mM 12 hrs, larvae L3
49
Cadmium 50 mM 48 hrs, 4-day adult
39
Cadmium 100 mM 48 hrs, 4-day adult
57
Copper 0.5 mM 12 hrs, larvae L3
13
Copper 15 mM 48 hrs, 4-day adult
98
Zinc 5 mM 12 hrs, larvae L3
11
Zinc 4.5 mM 48 hrs, 4-day adult
91
Ethanol 2.5% 3 hrs, larvae L3
54
Ethanol 5% 3 hrs, larvae L3
45
Ethanol 10% 3 hrs, larvae L3
31
Caffeine 1.5 mg/ml 4 hrs, larvae L3
38
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
75
Caffeine 25 mg/ml 48 hrs, 4-day adult
24
Paraquat 5 mM 48 hrs, 4-day adult
77
Paraquat 10 mM 48 hrs, 4-day adult
66
Rotenone 2 μg 12 hrs, larvae L3
43
Rotenone 8 μg 12 hrs, larvae L3
29
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
19
cold shock, 4-day adult
12
heat shock, 4-day adult
37
Cadmium 50 mM 6 hrs, larvae L3
32
Cadmium 50 mM 12 hrs, larvae L3
49
Cadmium 50 mM 48 hrs, 4-day adult
39
Cadmium 100 mM 48 hrs, 4-day adult
57
Copper 0.5 mM 12 hrs, larvae L3
13
Copper 15 mM 48 hrs, 4-day adult
98
Zinc 5 mM 12 hrs, larvae L3
11
Zinc 4.5 mM 48 hrs, 4-day adult
91
Ethanol 2.5% 3 hrs, larvae L3
54
Ethanol 5% 3 hrs, larvae L3
45
Ethanol 10% 3 hrs, larvae L3
31
Caffeine 1.5 mg/ml 4 hrs, larvae L3
38
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
75
Caffeine 25 mg/ml 48 hrs, 4-day adult
24
Paraquat 5 mM 48 hrs, 4-day adult
77
Paraquat 10 mM 48 hrs, 4-day adult
66
Rotenone 2 μg 12 hrs, larvae L3
43
Rotenone 8 μg 12 hrs, larvae L3
29
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 3 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 2 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Disrupted in Transgenic Constructs & Insertions
Transgenic Constructs Insertions insertion of enhancer trap
insertion of mobile activating element
Gene Ontology: Function, Process
& Cellular Component ( 4 unique terms ) Terms Based on
Experimental Evidence ( 0 terms ) Terms Based on Predictions or
Assertions ( 4 terms ) Molecular Function inferred from sequence or structural similarity with
UniProtKB:Q96A54
(assigned by UniProtKB)
Biological Process inferred from sequence or structural similarity with
UniProtKB:Q96A54
(assigned by UniProtKB)
inferred from sequence or structural similarity with
UniProtKB:Q96A54
(assigned by UniProtKB)
Cellular Component inferred from sequence or structural similarity with
UniProtKB:Q96A54
(assigned by UniProtKB)
Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A database of protein and genetic interactions
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (47)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG66WZV7 )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG6D7ZF6 )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG6SQVS4 )
Apis mellifera
Western honey bee
Amel\LOC550659
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG013710
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH19165
Atta cephalotes
Leafcutter ant
Acep\ACEP18105
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO18027
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL19706
Linepithema humile
Argentine ant
Lhum\LH18563
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB21075
Solenopsis invicta
Red fire ant
Sinv\SINV15268
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG6WDBT7 )
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa
(EOG6TTVBC )
Caenorhabditis elegans
Nematode
Caenorhabditis elegans
Nematode
Strongylocentrotus purpuratus
Purple sea urchin
Xenopus tropicalis
Western clawed frog
Xenopus tropicalis
Western clawed frog
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Rattus norvegicus
Norway rat
Rattus norvegicus
Norway rat
Human Orthologs (2)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 5 )Bloomington Harvard VDRC Genomic Clones ( 2 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 163 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for database merge of Additional comments Other Comments The
Hrp59 protein binds preferentially to a subset of mRNAs, including
CG5315 mRNA.
External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- A database of protein and genetic interactions
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 1 )Reported As Symbol Synonym Name Synonym Secondary FlyBase
IDs References ( 21 )Generate a list of List References by type
Recent research papers ( 2 )
Krauchunas et al., 2012, Dev. Biol. 370(1): 125--134Protein phosphorylation changes reveal new candidates in the regulation of egg activation and early embryogenesis in D. melanogaster. [FBrf0219342] Weber et al., 2012, PLoS ONE 7(4): e34745Genome-Wide Association Analysis of Oxidative Stress Resistance in Drosophila melanogaster. [FBrf0218073]