• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\CG6937

General Information
Symbol	Dmel\CG6937	Species	D. melanogaster
Name		Annotation symbol	CG6937
Feature type	protein_coding_gene	FlyBase ID	FBgn0038989
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	94B5-94B5	Sequence location	3R:18,410,495..18,411,931 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG6937 (FBgn0038989). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: mRNA binding. There is experimental evidence that it is involved in the biological process: neurogenesis. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Nucleotide-binding, alpha-beta plait; RNA recognition motif domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during early larval stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval trachea, adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1635058_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG6937. Gene sequence location is 3R:18410495..18411931.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 94B5-94B5   Limits computationally determined from genome sequence between P{lacW}Dph5L4910 and P{lacW}GclmL0580
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG6937 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.47
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG6937-RA FBtr0084266  NM_142809   1307   356
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG6937-PA   FBpp0083659   39.6   356   10.49     NP_651066   AAF56024
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • RNA recognition motif domain (IPR000504) Nucleotide-binding, alpha-beta plait (IPR012677)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA202006   AA264297   AA264892   AE014297 AAF56024   AY071293 AAL48915   BG640180   BI232103   BI236446   BP549999   BP550000   BQ103740   BT053677   CO266579   CO275919   EC197503   EC203436   EC210433   EC214959   EV582668   FD586282   FD586287   FD586725   FD586799   FD587448   GH741832   GH762504
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VCY1 Q8SYV4
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism   (Fisher et al., 2012) embryonic stage 7 -- 8   anterior endoderm anlage   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) hindgut anlage   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior endoderm   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 9 -- 10   anterior endoderm   (Fisher et al., 2012) foregut primordium   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) inclusive hindgut primordium   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior endoderm   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) dorsal pharyngeal muscle primordium   (Fisher et al., 2012) foregut primordium   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) hindgut proper primordium   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) salivary gland body primordium   (Fisher et al., 2012) Comment:reported as salivary gland primordium somatic muscle primordium   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) visceral muscle primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   dorsal pharyngeal muscle   (Fisher et al., 2012) embryonic anal pad   (Fisher et al., 2012) embryonic hindgut   (Fisher et al., 2012) embryonic/larval lymph gland   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) embryonic/larval muscle system   (Fisher et al., 2012) embryonic/larval somatic muscle   (Fisher et al., 2012) embryonic/larval visceral muscle   (Fisher et al., 2012) gonad   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval trachea, adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    136.3 Larval Midgut    38.4 Larval Hindgut    48.7 Larval Malpighian Tubules    12.3 Larval Fat Body    18.9 Larval Salivary Gland    89 Larval Trachea    140.375 Larval Carcass    78.775 Adult Head    27.2 Adult Eye    24.475 Adult Brain    34.4 Adult Thoracic-Abdominal Ganglion    25.9 Adult Crop    31.4 Adult Midgut    45.6 Adult Hindgut    30.9 Adult Malpighian Tubules    39.6 Adult Fat Body    58.9 Adult Salivary Gland    22.9 Adult Heart    35.35 Adult VirginFemale Spermatheca    22.7 Adult InseminatedFemale Spermatheca    37.5 Adult Ovary    412.9 Adult Testis    22.2 Adult Male Accessory Gland    98.2 Adult Carcass    27.7 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    136.3 Larval Midgut    38.4 Larval Hindgut    48.7 Larval Malpighian Tubules    12.3 Larval Fat Body    18.9 Larval Salivary Gland    89 Larval Trachea    140.375 Larval Carcass    78.775 Adult Head    27.2 Adult Eye    24.475 Adult Brain    34.4 Adult Thoracic-Abdominal Ganglion    25.9 Adult Crop    31.4 Adult Midgut    45.6 Adult Hindgut    30.9 Adult Malpighian Tubules    39.6 Adult Fat Body    58.9 Adult Salivary Gland    22.9 Adult Heart    35.35 Adult VirginFemale Spermatheca    22.7 Adult InseminatedFemale Spermatheca    37.5 Adult Ovary    412.9 Adult Testis    22.2 Adult Male Accessory Gland    98.2 Adult Carcass    27.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    136.3 Larval Midgut    38.4 Larval Hindgut    48.7 Larval Malpighian Tubules    12.3 Larval Fat Body    18.9 Larval Salivary Gland    89 Larval Trachea    140.375 Larval Carcass    78.775 Adult Head    27.2 Adult Eye    24.475 Adult Brain    34.4 Adult Thoracic-Abdominal Ganglion    25.9 Adult Crop    31.4 Adult Midgut    45.6 Adult Hindgut    30.9 Adult Malpighian Tubules    39.6 Adult Fat Body    58.9 Adult Salivary Gland    22.9 Adult Heart    35.35 Adult VirginFemale Spermatheca    22.7 Adult InseminatedFemale Spermatheca    37.5 Adult Ovary    412.9 Adult Testis    22.2 Adult Male Accessory Gland    98.2 Adult Carcass    27.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    136.3 Larval Midgut    38.4 Larval Hindgut    48.7 Larval Malpighian Tubules    12.3 Larval Fat Body    18.9 Larval Salivary Gland    89 Larval Trachea    140.375 Larval Carcass    78.775 Adult Head    27.2 Adult Eye    24.475 Adult Brain    34.4 Adult Thoracic-Abdominal Ganglion    25.9 Adult Crop    31.4 Adult Midgut    45.6 Adult Hindgut    30.9 Adult Malpighian Tubules    39.6 Adult Fat Body    58.9 Adult Salivary Gland    22.9 Adult Heart    35.35 Adult VirginFemale Spermatheca    22.7 Adult InseminatedFemale Spermatheca    37.5 Adult Ovary    412.9 Adult Testis    22.2 Adult Male Accessory Gland    98.2 Adult Carcass    27.7 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    136.3 Larval Midgut    38.4 Larval Hindgut    48.7 Larval Malpighian Tubules    12.3 Larval Fat Body    18.9 Larval Salivary Gland    89 Larval Trachea    140.375 Larval Carcass    78.775 Adult Head    27.2 Adult Eye    24.475 Adult Brain    34.4 Adult Thoracic-Abdominal Ganglion    25.9 Adult Crop    31.4 Adult Midgut    45.6 Adult Hindgut    30.9 Adult Malpighian Tubules    39.6 Adult Fat Body    58.9 Adult Salivary Gland    22.9 Adult Heart    35.35 Adult VirginFemale Spermatheca    22.7 Adult InseminatedFemale Spermatheca    37.5 Adult Ovary    412.9 Adult Testis    22.2 Adult Male Accessory Gland    98.2 Adult Carcass    27.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    136.3 Larval Midgut    38.4 Larval Hindgut    48.7 Larval Malpighian Tubules    12.3 Larval Fat Body    18.9 Larval Salivary Gland    89 Larval Trachea    140.375 Larval Carcass    78.775 Adult Head    27.2 Adult Eye    24.475 Adult Brain    34.4 Adult Thoracic-Abdominal Ganglion    25.9 Adult Crop    31.4 Adult Midgut    45.6 Adult Hindgut    30.9 Adult Malpighian Tubules    39.6 Adult Fat Body    58.9 Adult Salivary Gland    22.9 Adult Heart    35.35 Adult VirginFemale Spermatheca    22.7 Adult InseminatedFemale Spermatheca    37.5 Adult Ovary    412.9 Adult Testis    22.2 Adult Male Accessory Gland    98.2 Adult Carcass    27.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    136.3 Larval Midgut    38.4 Larval Hindgut    48.7 Larval Malpighian Tubules    12.3 Larval Fat Body    18.9 Larval Salivary Gland    89 Larval Trachea    140.375 Larval Carcass    78.775 Adult Head    27.2 Adult Eye    24.475 Adult Brain    34.4 Adult Thoracic-Abdominal Ganglion    25.9 Adult Crop    31.4 Adult Midgut    45.6 Adult Hindgut    30.9 Adult Malpighian Tubules    39.6 Adult Fat Body    58.9 Adult Salivary Gland    22.9 Adult Heart    35.35 Adult VirginFemale Spermatheca    22.7 Adult InseminatedFemale Spermatheca    37.5 Adult Ovary    412.9 Adult Testis    22.2 Adult Male Accessory Gland    98.2 Adult Carcass    27.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    136.3 Larval Midgut    38.4 Larval Hindgut    48.7 Larval Malpighian Tubules    12.3 Larval Fat Body    18.9 Larval Salivary Gland    89 Larval Trachea    140.375 Larval Carcass    78.775 Adult Head    27.2 Adult Eye    24.475 Adult Brain    34.4 Adult Thoracic-Abdominal Ganglion    25.9 Adult Crop    31.4 Adult Midgut    45.6 Adult Hindgut    30.9 Adult Malpighian Tubules    39.6 Adult Fat Body    58.9 Adult Salivary Gland    22.9 Adult Heart    35.35 Adult VirginFemale Spermatheca    22.7 Adult InseminatedFemale Spermatheca    37.5 Adult Ovary    412.9 Adult Testis    22.2 Adult Male Accessory Gland    98.2 Adult Carcass    27.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    27.2   NA  Eye    24.475   NA  Brain    34.4   136.3  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    25.9   NA  Crop    31.4   38.4  Midgut    45.6   48.7  Hindgut    30.9   no informative data  Malpighian Tubules    no informative data   no informative data  Fat Body    58.9   89  Salivary Gland    no informative data   NA  Heart    35.35   140.375  Trachea    NA   NA  VirginFemale Spermatheca    22.7   NA  InseminatedFemale Spermatheca    37.5   NA  Ovary    412.9   NA  Testis    22.2   NA  Male Accessory Gland    98.2   78.775  Carcass    no informative data FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    18 central nervous system, pupae P8    5 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    5 head, mated 1-day female    6 head, mated 4-day female    8 head, mated 20-day female    5 head, mated 1-day male    4 head, mated 4-day male    5 head, mated 20-day male    4 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    7 digestive system, 4-day adult    12 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    4 fat body, pupae P8    1 carcass, larvae L3 wandering    14 carcass, 1-day adult    5 carcass, 4-day adult    11 carcass, 20-day adult    8 ovary, virgin 4-day female    74 ovary, mated 4-day female    75 testis, mated 4-day male    13 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    18 central nervous system, pupae P8    5 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    5 head, mated 1-day female    6 head, mated 4-day female    8 head, mated 20-day female    5 head, mated 1-day male    4 head, mated 4-day male    5 head, mated 20-day male    4 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    7 digestive system, 4-day adult    12 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    4 fat body, pupae P8    1 carcass, larvae L3 wandering    14 carcass, 1-day adult    5 carcass, 4-day adult    11 carcass, 20-day adult    8 ovary, virgin 4-day female  (74) ovary, mated 4-day female  (75) testis, mated 4-day male    13 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    18 central nervous system, pupae P8    5 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    5 head, mated 1-day female    6 head, mated 4-day female    8 head, mated 20-day female    5 head, mated 1-day male    4 head, mated 4-day male    5 head, mated 20-day male    4 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    7 digestive system, 4-day adult    12 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    4 fat body, pupae P8    1 carcass, larvae L3 wandering    14 carcass, 1-day adult    5 carcass, 4-day adult    11 carcass, 20-day adult    8 ovary, virgin 4-day female    74 ovary, mated 4-day female    75 testis, mated 4-day male    13 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    18 central nervous system, pupae P8    5 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    5 head, mated 1-day female    6 head, mated 4-day female    8 head, mated 20-day female    5 head, mated 1-day male    4 head, mated 4-day male    5 head, mated 20-day male    4 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    7 digestive system, 4-day adult    12 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    4 fat body, pupae P8    1 carcass, larvae L3 wandering    14 carcass, 1-day adult    5 carcass, 4-day adult    11 carcass, 20-day adult    8 ovary, virgin 4-day female    74 ovary, mated 4-day female    75 testis, mated 4-day male    13 accessory gland, mated 4-day male    8 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    18 central nervous system, pupae P8    5 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    5 head, mated 1-day female    6 head, mated 4-day female    8 head, mated 20-day female    5 head, mated 1-day male    4 head, mated 4-day male    5 head, mated 20-day male    4 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    7 digestive system, 4-day adult    12 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    4 fat body, pupae P8    1 carcass, larvae L3 wandering    14 carcass, 1-day adult    5 carcass, 4-day adult    11 carcass, 20-day adult    8 ovary, virgin 4-day female    74 ovary, mated 4-day female    75 testis, mated 4-day male    13 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    18 central nervous system, pupae P8    5 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    5 head, mated 1-day female    6 head, mated 4-day female    8 head, mated 20-day female    5 head, mated 1-day male    4 head, mated 4-day male    5 head, mated 20-day male    4 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    7 digestive system, 4-day adult    12 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    4 fat body, pupae P8    1 carcass, larvae L3 wandering    14 carcass, 1-day adult    5 carcass, 4-day adult    11 carcass, 20-day adult    8 ovary, virgin 4-day female  (74) ovary, mated 4-day female  (75) testis, mated 4-day male    13 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    18 central nervous system, pupae P8    5 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    5 head, mated 1-day female    6 head, mated 4-day female    8 head, mated 20-day female    5 head, mated 1-day male    4 head, mated 4-day male    5 head, mated 20-day male    4 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    7 digestive system, 4-day adult    12 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    4 fat body, pupae P8    1 carcass, larvae L3 wandering    14 carcass, 1-day adult    5 carcass, 4-day adult    11 carcass, 20-day adult    8 ovary, virgin 4-day female    74 ovary, mated 4-day female    75 testis, mated 4-day male    13 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    18 central nervous system, pupae P8    5 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    5 head, mated 1-day female    6 head, mated 4-day female    8 head, mated 20-day female    5 head, mated 1-day male    4 head, mated 4-day male    5 head, mated 20-day male    4 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    7 digestive system, 4-day adult    12 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    4 fat body, pupae P8    1 carcass, larvae L3 wandering    14 carcass, 1-day adult    5 carcass, 4-day adult    11 carcass, 20-day adult    8 ovary, virgin 4-day female    74 ovary, mated 4-day female    75 testis, mated 4-day male    13 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during early larval stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    98 embryo 02-04hr    26 embryo 04-06hr    60 embryo 06-08hr    74 embryo 08-10hr    73 embryo 10-12hr    68 embryo 12-14hr    44 embryo 14-16hr    23 embryo 16-18hr    19 embryo 18-20hr    18 embryo 20-22hr    38 embryo 22-24hr    34 larva L1    68 larva L2    38 larva L3 12hr old    24 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    14 white prepupae 24hr    14 pupae 2d postWPP    12 pupae 3d postWPP    7 pupae 4d postWPP    8 adult male 01day    6 adult male 05day    7 adult male 30day    6 adult female 01day    37 adult female 05day    76 adult female 30day    78 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (98) embryo 02-04hr  26 embryo 04-06hr  (60) embryo 06-08hr  (74) embryo 08-10hr  (73) embryo 10-12hr  (68) embryo 12-14hr  (44) embryo 14-16hr    23 embryo 16-18hr    19 embryo 18-20hr    18 embryo 20-22hr  (38) embryo 22-24hr  (34) larva L1  (68) larva L2  (38) larva L3 12hr old    24 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    14 white prepupae 24hr    14 pupae 2d postWPP    12 pupae 3d postWPP    7 pupae 4d postWPP    8 adult male 01day    6 adult male 05day    7 adult male 30day    6 adult female 01day  (37) adult female 05day  (76) adult female 30day  (78) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    98 embryo 02-04hr    26 embryo 04-06hr    60 embryo 06-08hr    74 embryo 08-10hr    73 embryo 10-12hr    68 embryo 12-14hr    44 embryo 14-16hr    23 embryo 16-18hr    19 embryo 18-20hr    18 embryo 20-22hr    38 embryo 22-24hr    34 larva L1    68 larva L2    38 larva L3 12hr old    24 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    14 white prepupae 24hr    14 pupae 2d postWPP    12 pupae 3d postWPP    7 pupae 4d postWPP    8 adult male 01day    6 adult male 05day    7 adult male 30day    6 adult female 01day    37 adult female 05day    76 adult female 30day    78 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    98 embryo 02-04hr    26 embryo 04-06hr    60 embryo 06-08hr    74 embryo 08-10hr    73 embryo 10-12hr    68 embryo 12-14hr    44 embryo 14-16hr    23 embryo 16-18hr    19 embryo 18-20hr    18 embryo 20-22hr    38 embryo 22-24hr    34 larva L1    68 larva L2    38 larva L3 12hr old    24 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    14 white prepupae 24hr    14 pupae 2d postWPP    12 pupae 3d postWPP    7 pupae 4d postWPP    8 adult male 01day    6 adult male 05day    7 adult male 30day    6 adult female 01day    37 adult female 05day    76 adult female 30day    78 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    98 embryo 02-04hr    26 embryo 04-06hr    60 embryo 06-08hr    74 embryo 08-10hr    73 embryo 10-12hr    68 embryo 12-14hr    44 embryo 14-16hr    23 embryo 16-18hr    19 embryo 18-20hr    18 embryo 20-22hr    38 embryo 22-24hr    34 larva L1    68 larva L2    38 larva L3 12hr old    24 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    14 white prepupae 24hr    14 pupae 2d postWPP    12 pupae 3d postWPP    7 pupae 4d postWPP    8 adult male 01day    6 adult male 05day    7 adult male 30day    6 adult female 01day    37 adult female 05day    76 adult female 30day    78 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (98) embryo 02-04hr  26 embryo 04-06hr  (60) embryo 06-08hr  (74) embryo 08-10hr  (73) embryo 10-12hr  (68) embryo 12-14hr  (44) embryo 14-16hr    23 embryo 16-18hr    19 embryo 18-20hr    18 embryo 20-22hr  (38) embryo 22-24hr  (34) larva L1  (68) larva L2  (38) larva L3 12hr old    24 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    14 white prepupae 24hr    14 pupae 2d postWPP    12 pupae 3d postWPP    7 pupae 4d postWPP    8 adult male 01day    6 adult male 05day    7 adult male 30day    6 adult female 01day  (37) adult female 05day  (76) adult female 30day  (78) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    98 embryo 02-04hr    26 embryo 04-06hr    60 embryo 06-08hr    74 embryo 08-10hr    73 embryo 10-12hr    68 embryo 12-14hr    44 embryo 14-16hr    23 embryo 16-18hr    19 embryo 18-20hr    18 embryo 20-22hr    38 embryo 22-24hr    34 larva L1    68 larva L2    38 larva L3 12hr old    24 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    14 white prepupae 24hr    14 pupae 2d postWPP    12 pupae 3d postWPP    7 pupae 4d postWPP    8 adult male 01day    6 adult male 05day    7 adult male 30day    6 adult female 01day    37 adult female 05day    76 adult female 30day    78 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    98 embryo 02-04hr    26 embryo 04-06hr    60 embryo 06-08hr    74 embryo 08-10hr    73 embryo 10-12hr    68 embryo 12-14hr    44 embryo 14-16hr    23 embryo 16-18hr    19 embryo 18-20hr    18 embryo 20-22hr    38 embryo 22-24hr    34 larva L1    68 larva L2    38 larva L3 12hr old    24 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    14 white prepupae 24hr    14 pupae 2d postWPP    12 pupae 3d postWPP    7 pupae 4d postWPP    8 adult male 01day    6 adult male 05day    7 adult male 30day    6 adult female 01day    37 adult female 05day    76 adult female 30day    78 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    126 Schneider line 2 Sg4    48 embryonic 1182-4H    26 embryonic GM2    22 embryonic Kc167    40 embryonic S1    41 embryonic S3    47 leg disc CME L1    50 wing disc CME-W2    22 wing disc ML-DmD8    32 wing disc ML-DmD9    20 wing disc ML-DmD16-c3    49 wing disc ML-DmD21    51 wing disc ML-DmD32    56 haltere disc ML-DmD17-c3    35 eye-antennal disc ML-DmD11    38 antennal disc ML-DmD20-c5    42 mixed discs ML-DmD4-c1    55 CNS ML-DmBG1-c1    51 CNS ML-DmBG2-c2    26 tumorous blood cells mbn2    25 ovary fGS/OSS    21 ovary OSC    34 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (126) Schneider line 2 Sg4  (48) embryonic 1182-4H  26 embryonic GM2    22 embryonic Kc167  (40) embryonic S1  (41) embryonic S3  (47) leg disc CME L1  (50) wing disc CME-W2    22 wing disc ML-DmD8  (32) wing disc ML-DmD9    20 wing disc ML-DmD16-c3  (49) wing disc ML-DmD21  (51) wing disc ML-DmD32  (56) haltere disc ML-DmD17-c3  (35) eye-antennal disc ML-DmD11  (38) antennal disc ML-DmD20-c5  (42) mixed discs ML-DmD4-c1  (55) CNS ML-DmBG1-c1  (51) CNS ML-DmBG2-c2  26 tumorous blood cells mbn2    25 ovary fGS/OSS    21 ovary OSC  (34) ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (126) Schneider line 2 Sg4    48 embryonic 1182-4H    26 embryonic GM2    22 embryonic Kc167    40 embryonic S1    41 embryonic S3    47 leg disc CME L1    50 wing disc CME-W2    22 wing disc ML-DmD8    32 wing disc ML-DmD9    20 wing disc ML-DmD16-c3    49 wing disc ML-DmD21    51 wing disc ML-DmD32    56 haltere disc ML-DmD17-c3    35 eye-antennal disc ML-DmD11    38 antennal disc ML-DmD20-c5    42 mixed discs ML-DmD4-c1    55 CNS ML-DmBG1-c1    51 CNS ML-DmBG2-c2    26 tumorous blood cells mbn2    25 ovary fGS/OSS    21 ovary OSC    34 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    126 Schneider line 2 Sg4    48 embryonic 1182-4H    26 embryonic GM2    22 embryonic Kc167    40 embryonic S1    41 embryonic S3    47 leg disc CME L1    50 wing disc CME-W2    22 wing disc ML-DmD8    32 wing disc ML-DmD9    20 wing disc ML-DmD16-c3    49 wing disc ML-DmD21    51 wing disc ML-DmD32    56 haltere disc ML-DmD17-c3    35 eye-antennal disc ML-DmD11    38 antennal disc ML-DmD20-c5    42 mixed discs ML-DmD4-c1    55 CNS ML-DmBG1-c1    51 CNS ML-DmBG2-c2    26 tumorous blood cells mbn2    25 ovary fGS/OSS    21 ovary OSC    34 ovary OSS    17 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    126 Schneider line 2 Sg4    48 embryonic 1182-4H    26 embryonic GM2    22 embryonic Kc167    40 embryonic S1    41 embryonic S3    47 leg disc CME L1    50 wing disc CME-W2    22 wing disc ML-DmD8    32 wing disc ML-DmD9    20 wing disc ML-DmD16-c3    49 wing disc ML-DmD21    51 wing disc ML-DmD32    56 haltere disc ML-DmD17-c3    35 eye-antennal disc ML-DmD11    38 antennal disc ML-DmD20-c5    42 mixed discs ML-DmD4-c1    55 CNS ML-DmBG1-c1    51 CNS ML-DmBG2-c2    26 tumorous blood cells mbn2    25 ovary fGS/OSS    21 ovary OSC    34 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (126) Schneider line 2 Sg4  (48) embryonic 1182-4H  26 embryonic GM2    22 embryonic Kc167  (40) embryonic S1  (41) embryonic S3  (47) leg disc CME L1  (50) wing disc CME-W2    22 wing disc ML-DmD8  32 wing disc ML-DmD9    20 wing disc ML-DmD16-c3  (49) wing disc ML-DmD21  (51) wing disc ML-DmD32  (56) haltere disc ML-DmD17-c3  (35) eye-antennal disc ML-DmD11  (38) antennal disc ML-DmD20-c5  (42) mixed discs ML-DmD4-c1  (55) CNS ML-DmBG1-c1  (51) CNS ML-DmBG2-c2  26 tumorous blood cells mbn2    25 ovary fGS/OSS    21 ovary OSC  (34) ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  126 Schneider line 2 Sg4    48 embryonic 1182-4H    26 embryonic GM2    22 embryonic Kc167    40 embryonic S1    41 embryonic S3    47 leg disc CME L1    50 wing disc CME-W2    22 wing disc ML-DmD8    32 wing disc ML-DmD9    20 wing disc ML-DmD16-c3    49 wing disc ML-DmD21    51 wing disc ML-DmD32    56 haltere disc ML-DmD17-c3    35 eye-antennal disc ML-DmD11    38 antennal disc ML-DmD20-c5    42 mixed discs ML-DmD4-c1    55 CNS ML-DmBG1-c1    51 CNS ML-DmBG2-c2    26 tumorous blood cells mbn2    25 ovary fGS/OSS    21 ovary OSC    34 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    126 Schneider line 2 Sg4    48 embryonic 1182-4H    26 embryonic GM2    22 embryonic Kc167    40 embryonic S1    41 embryonic S3    47 leg disc CME L1    50 wing disc CME-W2    22 wing disc ML-DmD8    32 wing disc ML-DmD9    20 wing disc ML-DmD16-c3    49 wing disc ML-DmD21    51 wing disc ML-DmD32    56 haltere disc ML-DmD17-c3    35 eye-antennal disc ML-DmD11    38 antennal disc ML-DmD20-c5    42 mixed discs ML-DmD4-c1    55 CNS ML-DmBG1-c1    51 CNS ML-DmBG2-c2    26 tumorous blood cells mbn2    25 ovary fGS/OSS    21 ovary OSC    34 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    15 cold shock, 4-day adult    12 heat shock, 4-day adult    27 Cadmium 50 mM 6 hrs, larvae L3    12 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult    28 Cadmium 100 mM 48 hrs, 4-day adult    49 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    43 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    47 Caffeine 25 mg/ml 48 hrs, 4-day adult    21 Paraquat 5 mM 48 hrs, 4-day adult    40 Paraquat 10 mM 48 hrs, 4-day adult    28 Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    15 cold shock, 4-day adult    12 heat shock, 4-day adult  (27) Cadmium 50 mM 6 hrs, larvae L3    12 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult  (28) Cadmium 100 mM 48 hrs, 4-day adult  (49) Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3  (43) Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (47) Caffeine 25 mg/ml 48 hrs, 4-day adult    21 Paraquat 5 mM 48 hrs, 4-day adult  (40) Paraquat 10 mM 48 hrs, 4-day adult  (28) Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    20 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    15 cold shock, 4-day adult    12 heat shock, 4-day adult    27 Cadmium 50 mM 6 hrs, larvae L3    12 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult    28 Cadmium 100 mM 48 hrs, 4-day adult    49 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    43 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    47 Caffeine 25 mg/ml 48 hrs, 4-day adult    21 Paraquat 5 mM 48 hrs, 4-day adult    40 Paraquat 10 mM 48 hrs, 4-day adult    28 Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    15 cold shock, 4-day adult    12 heat shock, 4-day adult    27 Cadmium 50 mM 6 hrs, larvae L3    12 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult    28 Cadmium 100 mM 48 hrs, 4-day adult    49 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    43 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    47 Caffeine 25 mg/ml 48 hrs, 4-day adult    21 Paraquat 5 mM 48 hrs, 4-day adult    40 Paraquat 10 mM 48 hrs, 4-day adult    28 Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    20 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    15 cold shock, 4-day adult    12 heat shock, 4-day adult    27 Cadmium 50 mM 6 hrs, larvae L3    12 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult    28 Cadmium 100 mM 48 hrs, 4-day adult    49 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    43 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    47 Caffeine 25 mg/ml 48 hrs, 4-day adult    21 Paraquat 5 mM 48 hrs, 4-day adult    40 Paraquat 10 mM 48 hrs, 4-day adult    28 Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    15 cold shock, 4-day adult    12 heat shock, 4-day adult  27 Cadmium 50 mM 6 hrs, larvae L3    12 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult  28 Cadmium 100 mM 48 hrs, 4-day adult  (49) Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3  (43) Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (47) Caffeine 25 mg/ml 48 hrs, 4-day adult    21 Paraquat 5 mM 48 hrs, 4-day adult  (40) Paraquat 10 mM 48 hrs, 4-day adult  28 Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    20 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    15 cold shock, 4-day adult    12 heat shock, 4-day adult    27 Cadmium 50 mM 6 hrs, larvae L3    12 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult    28 Cadmium 100 mM 48 hrs, 4-day adult    49 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    43 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    47 Caffeine 25 mg/ml 48 hrs, 4-day adult    21 Paraquat 5 mM 48 hrs, 4-day adult    40 Paraquat 10 mM 48 hrs, 4-day adult    28 Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    15 cold shock, 4-day adult    12 heat shock, 4-day adult    27 Cadmium 50 mM 6 hrs, larvae L3    12 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult    28 Cadmium 100 mM 48 hrs, 4-day adult    49 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    43 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    47 Caffeine 25 mg/ml 48 hrs, 4-day adult    21 Paraquat 5 mM 48 hrs, 4-day adult    40 Paraquat 10 mM 48 hrs, 4-day adult    28 Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_08
External Data & Images
Linkouts	BDGP expression data • RE32504 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038989 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6937-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG6937 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal CG6937GD12080 lethal | pupal stage, with Scer\GAL4pnr-MD237 CG6937GD12080 Other Phenotypes Allele neuroanatomy defective | larval stage CG6937GD12080 Phenotype manifest in Allele embryonic/larval neuroblast | larval stage CG6937GD12080 ganglion mother cell | larval stage CG6937GD12080
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG6937 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG6937 Class Mutagen Stocks Known lesion CG6937GD12080 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG6937GL01252 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG6937KK102223 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG6937NIG.6937R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6273 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD12080} NA P{KK102223} NA P{NIG.6937R} NA P{TRiP.GL01252} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
neurogenesis inferred from mutant phenotype (Neumüller et al., 2011)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
mRNA binding inferred from sequence or structural similarity (Lasko, 2000) nucleic acid binding inferred from electronic annotation with InterPro:IPR000504 (FlyBase Curators et al., 2004-) nucleotide binding inferred from electronic annotation with InterPro:IPR012677 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG6937 - AP-2σ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - AR-2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Arf51F anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Arp1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Arpc4 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Ate1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Bsg anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Btk29A anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CDC45L anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG10086 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG10175 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG10209 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG10366 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG10465 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG10660 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG10681 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG10889 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG10934 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG10958 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG1105 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG1116 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG11190 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG11266 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG11279 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG11550 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG12171 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG12241 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG12818 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG13021 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG14020 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG14195 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG14722 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG14826 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG15096 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG15236 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG15343 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG15661 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG17601 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG17806 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG17841 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG1785 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG2519 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG30195 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG31111 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG31637 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG31694 experimental knowledge based (Guruharsha et al., 2011) CG6937 - CG31910 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG32278 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG32698 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG3530 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG3542 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG3838 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG3995 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG4151 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG4164 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG4302 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG4415 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG4610 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG4730 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG4766 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG4810 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG4815 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG4951 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG4962 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG5043 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG5087 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG5190 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG5196 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG5343 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG5516 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG5618 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG5660 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG5886 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG5961 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG6123 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG6227 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG6277 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG6652 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG6674 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG6927 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG7239 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG7542 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG7646 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG7845 experimental knowledge based (Guruharsha et al., 2011) CG6937 - CG8289 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG8765 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG8801 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) CG6937 - CG8924 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG8939 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) CG6937 - CG9062 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG9346 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CG9890 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CSN4 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Cct5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Cdc27 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Cen anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Chi anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CkIIα anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - CkIIα-i3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Clc anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Cyp6a21 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Df31 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Drat anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Drip anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - E(spl)m7-HLH anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Fas3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Gad1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - HDAC6 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Hcs anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Hph anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - ImpL2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Ip259 experimental knowledge based (Guruharsha et al., 2011) CG6937 - Jra anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Klp31E anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Kr-h1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Map205 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Mcm3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Mcm5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Mcm7 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Nle anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Ns1 experimental knowledge based (Guruharsha et al., 2011) CG6937 - Optix anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Osi9 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - PH4αSG1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Pi4KIIα anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Pitslre anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Pp1-87B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Rala anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Ran anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Rbm13 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Rcc1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Rcd5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Rho1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - RpL24-like anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - RpL7-like experimental knowledge based (Guruharsha et al., 2011) CG6937 - RpLP0 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - SNCF anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Sap130 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Sbp2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Socs44A anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Srp72 experimental knowledge based (Guruharsha et al., 2011) CG6937 - Sry-β anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Ssl anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - TM9SF4 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Timp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Tm1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - Tpc2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - ap anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - asun anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - botv anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - caup anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - cbx anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - dbe anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - dgo anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - dome anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - dpn anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - eIF-2α anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - eIF4E-6 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - elB anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - fabp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - grau anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - gus anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - l(1)G0020 experimental knowledge based (Guruharsha et al., 2011) CG6937 - l(1)G0193 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - l(1)G0469 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - lectin-46Ca anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - lkb1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - lwr anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - mts anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - phl anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - pit anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) CG6937 - sano anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - sc anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - skpA anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - slow anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - spoon anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - su(Hw) anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - tau anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - thoc5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - tra2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - vig anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - wdn anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - wupA anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - yellow-c anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6937 - zpg anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG6937 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 67616 DroID - A comprehensive database of gene and protein interactions. • FBgn0038989 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42662
Orthologs
OrthoDB Orthologs (35) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG605SMG Dipteran inclusive ortholog search EOG63R3WR Insect inclusive ortholog search EOG67H4MS Arthropod inclusive ortholog search EOG6K98VW Metazoa inclusive ortholog search EOG6Q5NHM
Orthologs in Drosophila Species (EOG605SMG)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG6937     Drosophila simulans   Dsim\GD20965 Y   Drosophila sechellia   Dsec\GM26446 Y   Drosophila erecta   Dere\GG11148 Y   Drosophila yakuba   Dyak\GE10313 Y   Drosophila ananassae   Dana\GF18861 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA19968 Y   Drosophila persimilis   Dper\GL13812 Y   Drosophila willistoni   Dwil\GK11303 Y   Drosophila virilis   Dvir\GJ23050 Y   Drosophila mojavensis   Dmoj\GI22244 Y   Drosophila grimshawi   Dgri\GH22444 Y
Orthologs in non-Drosophila Dipterans (EOG63R3WR)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL012100   Anopheles gambiae Malaria mosquito  Agam\AGAP006090   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ015549
Orthologs in non-Dipteran Insects (EOG67H4MS)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC552509   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG023378   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH23664   Atta cephalotes Leafcutter ant  Acep\ACEP14378   Camponotus floridanus Florida carpenter ant  Cflo\CFLO20292   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20087   Linepithema humile Argentine ant  Lhum\LH24948   Pogonomyrmex barbatus Red harvester ant  Pbar\PB21465   Acyrthosiphon pisum Pea aphid  Apim\ACYPI006149   Bombyx mori Silkmoth  Bmor\BGIBMGA004635   Tribolium castaneum Red flour beetle  Tcas\TC004828
Orthologs in non-Insect Arthropods (EOG6K98VW)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\COI
Orthologs in non-Arthropod Metazoa (EOG6Q5NHM)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\T04A8.6   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015927gn   Danio rerio Zebrafish  Drer\mki67ip   Xenopus tropicalis Western clawed frog  Xtro\mki67ip   Gallus gallus Domestic chicken  Ggal\MKI67IP   Mus musculus House mouse  Mmus\Mki67ip   Rattus norvegicus Norway rat  Rnor\Mki67ip   Homo sapiens Human  Hsap\MKI67IP
Human Orthologs (1)
Gene OMIM HGNC Hsap\MKI67IP
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD20965 Drosophila sechellia Dsec\GM26446 Drosophila erecta Dere\GG11148 Drosophila yakuba Dyak\GE10313 Drosophila ananassae Dana\GF18861 Drosophila pseudoobscura pseudoobscura Dpse\GA19968 Drosophila persimilis Dper\GL13812 Drosophila willistoni Dwil\GK11303 Drosophila virilis Dvir\GJ23050 Drosophila mojavensis Dmoj\GI22244 Drosophila grimshawi Dgri\GH22444
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	41824 y1 v1; P{TRiP.GL01252}attP2/TM3, Sb1
VDRC	v103728 P{KK102223}VIE-260B v22315 w1118; P{GD12080}v22315
Genomic Clones ( 2 )
	BACR02L12 BACR48C17 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 23 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE32504
Other clones	FI03269
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LD03888 LD07980 LD09522 RE28119 SD11143
Other clones	35861 146239 149632 CK01.144C.A2 Dmel_dig_018060_0599_2988 EK119133 EK146928 FGM104G01 RM04253 RM04353 RM04653 RM04853 RM04953 RP001044751 RP001051479 UUGC1151
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0038989 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42662
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	Identified as a potential component of the hh signalling pathway in a genome-wide RNAi screen. dsRNA made from templates generated with primers directed affects the extent of expression of a hh signaling reporter construct in Clone 8 cells. (Nybakken et al., 2005)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_142809 RefSeq (Proteins) • NP_651066 DDBJ / EMBL / GenBank • AAF56024 AAL48915 AY071293 BI236446 Entrez Gene - A searchable database of RefSeq genes. • 42662 UniProtKB/TrEMBL • Q8SYV4 Q9VCY1
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • RNA recognition motif domain (IPR000504) Nucleotide-binding, alpha-beta plait (IPR012677) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RE32504
Linkouts
	BioGRID - A database of protein and genetic interactions • 67616 DroID - A comprehensive database of gene and protein interactions. • FBgn0038989 DRSC - Results from RNAi screens. • FBgn0038989 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0038989 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6937-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0038989 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42662 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42662 modMine - Data generated by the modENCODE project. • FBgn0038989
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	cg6937 (Lasko, 2000) CG6937 (Nybakken et al., 2005, Somma et al., 2008, McGraw et al., 2008, Keleman et al., 2009.8.5, Japanese National Institute of Genetics, 2012.5.21, Ni et al., 2010.12.1)
Name Synonym
Secondary FlyBase IDs
References ( 23 )
Generate a list of	All references relating to this gene ( 23 )
List References by type	Research paper  ( 5 ) Supplementary material  ( 5 ) Personal communication to FlyBase  ( 7 ) FlyBase analysis  ( 1 ) Stock list  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...