• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • CytoSearch
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Downloads:
  • Precomputed files
  • Archived data
  • Releases (FTP)
  • Genomes (FTP)
  • AAA data (FTP)
  • Lists:
  • Transposons (Dmel)
  • Transposons (other)
  • Vectors & Constructs
  • Anatomical Terms
  • Map Conversion
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Other links:
  • BDGP
  • DGRC
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\EloA

General Information
Symbol	Dmel\EloA	Species	D. melanogaster
Name	Elongin A	Annotation symbol	CG6755
Feature type	protein_coding_gene	FlyBase ID	FBgn0039066
Gene Model Status	Current	Stock availability	2 publicly available
Also Known As	dEloA
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	94E9-94E9	Sequence location	3R:19,077,266..19,080,793 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Elongin A is referred to in FlyBase by the symbol Dmel\EloA (CG6755, FBgn0039066). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: DNA binding. There is experimental evidence that it is involved in the biological process: positive regulation of transcription elongation from RNA polymerase II promoter. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: RNA polymerase II transcription factor SIII, subunit A; Transcription factor IIS, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, larval/adult salivary gland, adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1632158_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of EloA. Gene sequence location is 3R:19077266..19080793.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features HFA16109 BKN21222 Controlled Vocabulary Terms nucleus positive regulation of transcription elongation from RNA polymerase II promoter transcriptionally active chromatin elongin complex
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 94E9-94E9   Limits computationally determined from genome sequence between P{PZ}cnc03921 and P{PZ}l(3)0690606906
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\EloA for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) EloA-RA FBtr0084374  NM_170061   2888   643 EloA-RB FBtr0084375  NM_142878   2716   566
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein EloA-PA   FBpp0083766   71.2   643   10.45     NP_732846   AAF56117 EloA-PB   FBpp0083767   62.5   566   10.45     NP_651135   AAN13934
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • RNA polymerase II transcription factor SIII, subunit A (IPR010684) Transcription factor IIS, N-terminal (IPR017923)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201913   AA263345   AA439279   AA441123   AA735476   AA950135   AA979507   AE014297 AAF56117   AE014297 AAN13934   AI512004   AI514717   AW942902   AY061363 AAL28911   BF492426   BF499873   BF504565   BG639000   BG639099   BI170730   BI172176   BI172898   BI173022   BI215691   BI229297   BI229631   BI231278   BI232048   BI232065   BI234327   BI243169   BI356543   BI373151   BI483224   BI483625   BI485987   BI486991   BT003775   CA806799   CO187582   CO265672   CO276910   CO279536   CO297923   CO318849   CO319479   CO328785   CO332551   CO333181   CO342992   EC060730   EC066075   EC071698   EC088341   EC199918   EC201261   EC206555   EC210234   EC224476   EC227299   EC228294   EC233257   EC251156   EC251349   GH751032   GH753325   GH753330   GH756446   GH760746   GH760787   GH770317   GH777415   GH777685   GH777730   GH779925   GH782645   GH783134   GH786446   GH787045   GH791695   GH792277   GH792813   GH794795   GH795415   GH795548   GH796465   GH801362   GH801791   GH802299   GH803016   GH803038   GH804275   GH810470   GH817618   GH819214   GH831603   GH832892   GH834688   GH836941   GH840670   GH841922   GH846977   GH848388   GH848641   GH851529   GH852194   GH852256   GH853542   GH854636   GH855338   GH855482   GH856126   GH856644   GH857872   GH860650   GH864685   GH864905   GH865528   GH866168   GH867268   GH873384   GH875260   GH880579   GH880904   GH882774   GH885975   GH886051   GH890759   GH892311   GH894320   GH894642   GH894952   GH899027   GH910219   GH915100   GH919913   GH921878   GH929208   GH929643   GH931216   GH932667   GH933593   GH934457   GH934819
UniProtKB/Swiss-Prot	Q9VCP0
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0039066    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0039066 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0039066 expression level Developmental Stage   Expression Level embryo 00-02hr    4986 embryo 02-04hr    4814 embryo 04-06hr    3967 embryo 06-08hr    2588 embryo 08-10hr    2600 embryo 10-12hr    1868 embryo 12-14hr    1987 embryo 14-16hr    1642 embryo 16-18hr    1500 embryo 18-20hr    963 embryo 20-22hr    2386 embryo 22-24hr    2249 larva L1    546 larva L2    648 larva L3 12hr old    516 larva L3 puffstage 1-2    562 larva L3 puffstage 3-6    921 larva L3 puffstage 7-9    1316 white prepupae new    1305 white prepupae 12hr    1145 white prepupae 24hr    1213 pupae 2d postWPP    1142 pupae 3d postWPP    800 pupae 4d postWPP    736 adult male 01day    943 adult male 05day    1151 adult male 30day    966 adult female 01day    1228 adult female 05day    2620 adult female 30day    2744 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4986) embryo 02-04hr  (4814) embryo 04-06hr  (3967) embryo 06-08hr  (2588) embryo 08-10hr  (2600) embryo 10-12hr  (1868) embryo 12-14hr  (1987) embryo 14-16hr  (1642) embryo 16-18hr  (1500) embryo 18-20hr  (963) embryo 20-22hr  (2386) embryo 22-24hr  (2249) larva L1  (546) larva L2  (648) larva L3 12hr old  (516) larva L3 puffstage 1-2  (562) larva L3 puffstage 3-6  (921) larva L3 puffstage 7-9  (1316) white prepupae new  (1305) white prepupae 12hr  (1145) white prepupae 24hr  (1213) pupae 2d postWPP  (1142) pupae 3d postWPP  (800) pupae 4d postWPP  (736) adult male 01day  (943) adult male 05day  (1151) adult male 30day  (966) adult female 01day  (1228) adult female 05day  (2620) adult female 30day  (2744) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4986) embryo 02-04hr  (4814) embryo 04-06hr  (3967) embryo 06-08hr  (2588) embryo 08-10hr  (2600) embryo 10-12hr  (1868) embryo 12-14hr  (1987) embryo 14-16hr  (1642) embryo 16-18hr  1500 embryo 18-20hr    963 embryo 20-22hr  (2386) embryo 22-24hr  (2249) larva L1    546 larva L2    648 larva L3 12hr old    516 larva L3 puffstage 1-2    562 larva L3 puffstage 3-6    921 larva L3 puffstage 7-9    1316 white prepupae new    1305 white prepupae 12hr    1145 white prepupae 24hr    1213 pupae 2d postWPP    1142 pupae 3d postWPP    800 pupae 4d postWPP    736 adult male 01day    943 adult male 05day    1151 adult male 30day    966 adult female 01day    1228 adult female 05day  (2620) adult female 30day  (2744) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4986 embryo 02-04hr    4814 embryo 04-06hr    3967 embryo 06-08hr    2588 embryo 08-10hr    2600 embryo 10-12hr    1868 embryo 12-14hr    1987 embryo 14-16hr    1642 embryo 16-18hr    1500 embryo 18-20hr    963 embryo 20-22hr    2386 embryo 22-24hr    2249 larva L1    546 larva L2    648 larva L3 12hr old    516 larva L3 puffstage 1-2    562 larva L3 puffstage 3-6    921 larva L3 puffstage 7-9    1316 white prepupae new    1305 white prepupae 12hr    1145 white prepupae 24hr    1213 pupae 2d postWPP    1142 pupae 3d postWPP    800 pupae 4d postWPP    736 adult male 01day    943 adult male 05day    1151 adult male 30day    966 adult female 01day    1228 adult female 05day    2620 adult female 30day    2744 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4986 embryo 02-04hr    4814 embryo 04-06hr    3967 embryo 06-08hr    2588 embryo 08-10hr    2600 embryo 10-12hr    1868 embryo 12-14hr    1987 embryo 14-16hr    1642 embryo 16-18hr    1500 embryo 18-20hr    963 embryo 20-22hr    2386 embryo 22-24hr    2249 larva L1    546 larva L2    648 larva L3 12hr old    516 larva L3 puffstage 1-2    562 larva L3 puffstage 3-6    921 larva L3 puffstage 7-9    1316 white prepupae new    1305 white prepupae 12hr    1145 white prepupae 24hr    1213 pupae 2d postWPP    1142 pupae 3d postWPP    800 pupae 4d postWPP    736 adult male 01day    943 adult male 05day    1151 adult male 30day    966 adult female 01day    1228 adult female 05day    2620 adult female 30day    2744 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0039066 expression level Developmental Stage   Expression Level embryo 00-02hr    4986 embryo 02-04hr    4814 embryo 04-06hr    3967 embryo 06-08hr    2588 embryo 08-10hr    2600 embryo 10-12hr    1868 embryo 12-14hr    1987 embryo 14-16hr    1642 embryo 16-18hr    1500 embryo 18-20hr    963 embryo 20-22hr    2386 embryo 22-24hr    2249 larva L1    546 larva L2    648 larva L3 12hr old    516 larva L3 puffstage 1-2    562 larva L3 puffstage 3-6    921 larva L3 puffstage 7-9    1316 white prepupae new    1305 white prepupae 12hr    1145 white prepupae 24hr    1213 pupae 2d postWPP    1142 pupae 3d postWPP    800 pupae 4d postWPP    736 adult male 01day    943 adult male 05day    1151 adult male 30day    966 adult female 01day    1228 adult female 05day    2620 adult female 30day    2744 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4986) embryo 02-04hr  (4814) embryo 04-06hr  (3967) embryo 06-08hr  (2588) embryo 08-10hr  (2600) embryo 10-12hr  (1868) embryo 12-14hr  (1987) embryo 14-16hr  (1642) embryo 16-18hr  (1500) embryo 18-20hr  (963) embryo 20-22hr  (2386) embryo 22-24hr  (2249) larva L1  (546) larva L2  (648) larva L3 12hr old  (516) larva L3 puffstage 1-2  (562) larva L3 puffstage 3-6  (921) larva L3 puffstage 7-9  (1316) white prepupae new  (1305) white prepupae 12hr  (1145) white prepupae 24hr  (1213) pupae 2d postWPP  (1142) pupae 3d postWPP  (800) pupae 4d postWPP  (736) adult male 01day  (943) adult male 05day  (1151) adult male 30day  (966) adult female 01day  (1228) adult female 05day  (2620) adult female 30day  (2744) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4986) embryo 02-04hr  (4814) embryo 04-06hr  (3967) embryo 06-08hr  (2588) embryo 08-10hr  (2600) embryo 10-12hr  1868 embryo 12-14hr  1987 embryo 14-16hr  1642 embryo 16-18hr  1500 embryo 18-20hr    963 embryo 20-22hr  2386 embryo 22-24hr  2249 larva L1    546 larva L2    648 larva L3 12hr old    516 larva L3 puffstage 1-2    562 larva L3 puffstage 3-6    921 larva L3 puffstage 7-9    1316 white prepupae new    1305 white prepupae 12hr    1145 white prepupae 24hr    1213 pupae 2d postWPP    1142 pupae 3d postWPP    800 pupae 4d postWPP    736 adult male 01day    943 adult male 05day    1151 adult male 30day    966 adult female 01day    1228 adult female 05day  (2620) adult female 30day  (2744) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4986 embryo 02-04hr    4814 embryo 04-06hr    3967 embryo 06-08hr    2588 embryo 08-10hr    2600 embryo 10-12hr    1868 embryo 12-14hr    1987 embryo 14-16hr    1642 embryo 16-18hr    1500 embryo 18-20hr    963 embryo 20-22hr    2386 embryo 22-24hr    2249 larva L1    546 larva L2    648 larva L3 12hr old    516 larva L3 puffstage 1-2    562 larva L3 puffstage 3-6    921 larva L3 puffstage 7-9    1316 white prepupae new    1305 white prepupae 12hr    1145 white prepupae 24hr    1213 pupae 2d postWPP    1142 pupae 3d postWPP    800 pupae 4d postWPP    736 adult male 01day    943 adult male 05day    1151 adult male 30day    966 adult female 01day    1228 adult female 05day    2620 adult female 30day    2744 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4986 embryo 02-04hr    4814 embryo 04-06hr    3967 embryo 06-08hr    2588 embryo 08-10hr    2600 embryo 10-12hr    1868 embryo 12-14hr    1987 embryo 14-16hr    1642 embryo 16-18hr    1500 embryo 18-20hr    963 embryo 20-22hr    2386 embryo 22-24hr    2249 larva L1    546 larva L2    648 larva L3 12hr old    516 larva L3 puffstage 1-2    562 larva L3 puffstage 3-6    921 larva L3 puffstage 7-9    1316 white prepupae new    1305 white prepupae 12hr    1145 white prepupae 24hr    1213 pupae 2d postWPP    1142 pupae 3d postWPP    800 pupae 4d postWPP    736 adult male 01day    943 adult male 05day    1151 adult male 30day    966 adult female 01day    1228 adult female 05day    2620 adult female 30day    2744 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0039066    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0039066 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, larval/adult salivary gland, adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0039066 expression level Tissue   Expression Level Larval Central Nervous System    142.1 Larval Midgut    81.5 Larval Hindgut    89.1 Larval Malpighian Tubules    88.2 Larval Fat Body    95.1 Larval Salivary Gland    133.6 Larval Trachea    94.225 Larval Carcass    91.4 Adult Head    59.9 Adult Eye    79.15 Adult Brain    137.6 Adult Thoracic-Abdominal Ganglion    122.7 Adult Crop    80.3 Adult Midgut    67.3 Adult Hindgut    65.6 Adult Malpighian Tubules    70.2 Adult Fat Body    79.7 Adult Salivary Gland    121.2 Adult Heart    77.9 Adult VirginFemale Spermatheca    53.9 Adult InseminatedFemale Spermatheca    56.1 Adult Ovary    347.8 Adult Testis    94.5 Adult Male Accessory Gland    62.9 Adult Carcass    74.3 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    142.1 Larval Midgut    81.5 Larval Hindgut    89.1 Larval Malpighian Tubules    88.2 Larval Fat Body    95.1 Larval Salivary Gland    133.6 Larval Trachea    94.225 Larval Carcass    91.4 Adult Head    59.9 Adult Eye    79.15 Adult Brain    137.6 Adult Thoracic-Abdominal Ganglion    122.7 Adult Crop    80.3 Adult Midgut    67.3 Adult Hindgut    65.6 Adult Malpighian Tubules    70.2 Adult Fat Body    79.7 Adult Salivary Gland    121.2 Adult Heart    77.9 Adult VirginFemale Spermatheca    53.9 Adult InseminatedFemale Spermatheca    56.1 Adult Ovary    347.8 Adult Testis    94.5 Adult Male Accessory Gland    62.9 Adult Carcass    74.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    142.1 Larval Midgut    81.5 Larval Hindgut    89.1 Larval Malpighian Tubules    88.2 Larval Fat Body    95.1 Larval Salivary Gland    133.6 Larval Trachea    94.225 Larval Carcass    91.4 Adult Head    59.9 Adult Eye    79.15 Adult Brain    137.6 Adult Thoracic-Abdominal Ganglion    122.7 Adult Crop    80.3 Adult Midgut    67.3 Adult Hindgut    65.6 Adult Malpighian Tubules    70.2 Adult Fat Body    79.7 Adult Salivary Gland    121.2 Adult Heart    77.9 Adult VirginFemale Spermatheca    53.9 Adult InseminatedFemale Spermatheca    56.1 Adult Ovary    347.8 Adult Testis    94.5 Adult Male Accessory Gland    62.9 Adult Carcass    74.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    142.1 Larval Midgut    81.5 Larval Hindgut    89.1 Larval Malpighian Tubules    88.2 Larval Fat Body    95.1 Larval Salivary Gland    133.6 Larval Trachea    94.225 Larval Carcass    91.4 Adult Head    59.9 Adult Eye    79.15 Adult Brain    137.6 Adult Thoracic-Abdominal Ganglion    122.7 Adult Crop    80.3 Adult Midgut    67.3 Adult Hindgut    65.6 Adult Malpighian Tubules    70.2 Adult Fat Body    79.7 Adult Salivary Gland    121.2 Adult Heart    77.9 Adult VirginFemale Spermatheca    53.9 Adult InseminatedFemale Spermatheca    56.1 Adult Ovary    347.8 Adult Testis    94.5 Adult Male Accessory Gland    62.9 Adult Carcass    74.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0039066 expression level Tissue   Expression Level Larval Central Nervous System    142.1 Larval Midgut    81.5 Larval Hindgut    89.1 Larval Malpighian Tubules    88.2 Larval Fat Body    95.1 Larval Salivary Gland    133.6 Larval Trachea    94.225 Larval Carcass    91.4 Adult Head    59.9 Adult Eye    79.15 Adult Brain    137.6 Adult Thoracic-Abdominal Ganglion    122.7 Adult Crop    80.3 Adult Midgut    67.3 Adult Hindgut    65.6 Adult Malpighian Tubules    70.2 Adult Fat Body    79.7 Adult Salivary Gland    121.2 Adult Heart    77.9 Adult VirginFemale Spermatheca    53.9 Adult InseminatedFemale Spermatheca    56.1 Adult Ovary    347.8 Adult Testis    94.5 Adult Male Accessory Gland    62.9 Adult Carcass    74.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    142.1 Larval Midgut    81.5 Larval Hindgut    89.1 Larval Malpighian Tubules    88.2 Larval Fat Body    95.1 Larval Salivary Gland    133.6 Larval Trachea    94.225 Larval Carcass    91.4 Adult Head    59.9 Adult Eye    79.15 Adult Brain    137.6 Adult Thoracic-Abdominal Ganglion    122.7 Adult Crop    80.3 Adult Midgut    67.3 Adult Hindgut    65.6 Adult Malpighian Tubules    70.2 Adult Fat Body    79.7 Adult Salivary Gland    121.2 Adult Heart    77.9 Adult VirginFemale Spermatheca    53.9 Adult InseminatedFemale Spermatheca    56.1 Adult Ovary    347.8 Adult Testis    94.5 Adult Male Accessory Gland    62.9 Adult Carcass    74.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    142.1 Larval Midgut    81.5 Larval Hindgut    89.1 Larval Malpighian Tubules    88.2 Larval Fat Body    95.1 Larval Salivary Gland    133.6 Larval Trachea    94.225 Larval Carcass    91.4 Adult Head    59.9 Adult Eye    79.15 Adult Brain    137.6 Adult Thoracic-Abdominal Ganglion    122.7 Adult Crop    80.3 Adult Midgut    67.3 Adult Hindgut    65.6 Adult Malpighian Tubules    70.2 Adult Fat Body    79.7 Adult Salivary Gland    121.2 Adult Heart    77.9 Adult VirginFemale Spermatheca    53.9 Adult InseminatedFemale Spermatheca    56.1 Adult Ovary    347.8 Adult Testis    94.5 Adult Male Accessory Gland    62.9 Adult Carcass    74.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    142.1 Larval Midgut    81.5 Larval Hindgut    89.1 Larval Malpighian Tubules    88.2 Larval Fat Body    95.1 Larval Salivary Gland    133.6 Larval Trachea    94.225 Larval Carcass    91.4 Adult Head    59.9 Adult Eye    79.15 Adult Brain    137.6 Adult Thoracic-Abdominal Ganglion    122.7 Adult Crop    80.3 Adult Midgut    67.3 Adult Hindgut    65.6 Adult Malpighian Tubules    70.2 Adult Fat Body    79.7 Adult Salivary Gland    121.2 Adult Heart    77.9 Adult VirginFemale Spermatheca    53.9 Adult InseminatedFemale Spermatheca    56.1 Adult Ovary    347.8 Adult Testis    94.5 Adult Male Accessory Gland    62.9 Adult Carcass    74.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    59.9   NA  Eye    79.15   NA  Brain    137.6   142.1  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    122.7   NA  Crop    80.3   81.5  Midgut    67.3   89.1  Hindgut    65.6   88.2  Malpighian Tubules    70.2   95.1  Fat Body    79.7   133.6  Salivary Gland    121.2   NA  Heart    77.9   94.225  Trachea    NA   NA  VirginFemale Spermatheca    53.9   NA  InseminatedFemale Spermatheca    56.1   NA  Ovary    347.8   NA  Testis    94.5   NA  Male Accessory Gland    62.9   91.4  Carcass    74.3 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_01
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039066 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6755-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for EloA Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4Act5C.PU EloAdsRNA.Sym.Scer\UAS lethal | pupal stage, with Scer\GAL4da.G32 EloAdsRNA.Sym.Scer\UAS viable, with Scer\GAL4pnr-MD237 EloAGD1290 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of EloA Class Mutagen Stocks Known lesion EloAG4930 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of EloA Class Mutagen Stocks Known lesion EloAGD1290 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes EloAdsRNA.Sym.Scer\UAS in vitro construct - regulatory fusion in vitro construct - RNAi 0 Yes EloAKK101126 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6274 (Ryder, 2004.4.26) Df(3R)Exel6280 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD1290} NA P{KK101126} NA P{Sym-UAS-EloA} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}EloAG4930 NA P{GSV1}C411C411 NA P{GSV1}EP-820EP-820 NA
Gene Ontology: Function, Process & Cellular Component ( 8 unique terms )
Terms Based on Experimental Evidence ( 3 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
positive regulation of transcription elongation from RNA polymerase II promoter inferred from direct assay (Gerber et al., 2004)
Cellular Component
CV term Evidence References
nucleus inferred from direct assay (Gerber et al., 2004) colocalizes_with transcriptionally active chromatin inferred from direct assay (Gerber et al., 2004)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
DNA binding inferred from electronic annotation with InterPro:IPR017923 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
transcription elongation from RNA polymerase II promoter inferred from sequence or structural similarity with UniProtKB:Q63187 (assigned by UniProtKB) (Swiss-Prot Project Members, 2004.10.25)
Cellular Component
CV term Evidence References
elongin complex inferred from sequence or structural similarity with rat Tceb3 (Gerber et al., 2004) integral to membrane inferred from electronic annotation with InterPro:IPR010684 (FlyBase Curators et al., 2004-) transcription elongation factor complex inferred from sequence or structural similarity with UniProtKB:Q63187 (assigned by UniProtKB) (Swiss-Prot Project Members, 2004.10.25)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions EloA allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 67692 DroID - A comprehensive database of gene and protein interactions. • FBgn0039066 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42749
Orthologs
Genome-wide drosophilid orthologs	Dana\GF16986 Dere\GG11195 Dgri\GH18516 Dmoj\GI24361 Dper\GL24491 Dpse\GA19837 Dsec\GM26494 Dsim\GD21008 Dvir\GJ24371 Dwil\GK14059 Dyak\GE10362
Curated drosophilid orthologs	Dpse\GA19837
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL010723-PA Aedes aegypti (mosquito) XP_396851.3 Apis mellifera (honey bee) XP_001944769.1 Acyrthosiphon pisum (pea aphid) 89229 Branchiostoma floridae (lancelet) BGIBMGA006506-PA Bombyx mori (silk worm) CN04710 Caenorhabditis brenneri (small nematode) CBP11615 Caenorhabditis briggsae (nematode) CE01611 Caenorhabditis elegans (worm) ENSCAFP00000019484 Canis familiaris (dog) ENSCINP00000008547 Ciona intestinalis (sea squirt) JA03534 Caenorhabditis japonica (nematode) CPIJ003427 Culex pipens (mosquito) ENSCPOP00000007754 Cavia porcellus (guinea pig) RP23940 Caenorhabditis remanei (nematode) 220355 Capitella spl (polychaete worm) 221473 Daphnia pulex (daphnia) ENSDARP00000027752 Danio rerio (zebra fish) ENSECAP00000015945 Equus caballus (horse) ENSGACP00000002713 Gymnopilus aculeatus (mushroom) ENSGALP00000034307 Gallus gallus (chicken) ENSP00000363662 Homo sapiens (human) ISCW007299-PA Ixodes scapularis (deer tick) 171838 Lottia gigantea (owl limpet) ENSMODP00000016070 Monodelphis domestica (gray opossum) ENSMMUP00000004240 Macaca mulatta (rhesus monkey) ENSMUSP00000030427 Mus musculus (house mouse) 199556 Nematostella vectensis (starlet anemone) XP_001607275.1 Nasonia vitripennis (wasp) ENSOANP00000008726 Ornithorynchus anatinus (platypus) ENSORLP00000012323 Oryzias latipes (japanese killifish) LOC_Os11g06650.1 Oryza sativa (asian rice) PHUM006929-PA Pediculus humanus (human body louse) PP27394 Pristionchus pacificus (nematode) ENSPPYP00000002009 Pongo pygmaeus (orangutan) ENSPTRP00000000585 Pan troglodytes (chimpanzee) ENSRNOP00000015649 Rattus norvegicus (norway rat) Smp_143350 Schistosoma mansoni (trematode parasite) XP_797640.2 Strongylocentrotus purpuratus (purple sea urchin) XP_966848.1 Tribolium castaneum (red flour beetle) ENSTNIP00000019663 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000009784 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000046737 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV14080 LH22664 ISCW007299 FBgn0228229 FBgn0216065 FBgn0211451 FBgn0192463 FBgn0181347 JGI_V11_221473 FBgn0079833 FBgn0162080 FBgn0147084 FBgn0125983 FBgn0103496 FBgn0094005 CPIJ003427 BGIBMGA006506 ACYPI006169 GB12764 AGAP004363 AAEL010723 PB21793 PHUM128980 GLEAN_01477
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
Bloomington	30108 w1118; P{EP}EloAG4930
VDRC	v6282 w1118; P{GD1290}v6282
Genomic Clones ( 2 )
	BACR01E13 BACR03N12 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 136 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD28673 RE20724
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT06148 AT14646 AT29366 LD03995 LD06469 LD13802 LD16016 LD21376 LD34114 RE12282 RE14461 RE15592 RE15753 RE22277 RE27053 RE27451 RE28050 RE28072 RE30017 RE40733 RE42720 RE60373 RE66085 RE66542 RE69352 RE70483
Other clones	1308 19298 21132 32879 53553 73694 76965 117997 148089 173839 277118 281266 283489 CK01.35D.B10 EK030538 EK122362 EK135110 EK143345 EK170927 EK274502 EK278335 EK291416 EK303841 EK306127 EP15903 ESG015a.E21_C09 LD41213 LD43605 RP003012682 RP003021714 RP003021739 RP003027254 RP003036396 RP003053058 RP003067603 RP003078539 RP003078950 RP003089351 RP003090554 RP003101539 RP003108041 RP003142473 RP003162337 RP003168281 RP003168351 RP003190232 RP003193924 RP003199562 RP003211471 RP003212549 RP003212921 RP003218910 RP003218954 RP003225196 RP003229880 RP003233389 RP003245222 RP003258909 RP003291501 RP003307631 RP003317007 RP003323145 RP003330236 RP003345847 RP003356952 RP003378467 RP003380347 RP003393994 RP003416176 RP003418792 RP003419830 RP003427906 RP003439744 RP003441322 RP003449620 RP003462158 RP003471270 RP003474977 RP003488973 RP003491147 RP003499729 RP003503843 RP003505353 RP003511849 RP003517655 RP003528656 RP003529630 RP003534214 RP003556877 RP003559580 RP003562089 RP003567734 RP003576856 RP003579760 RP003593589 RP003599092 RP003631056 RP003631777 RP003632808 RP003640959 RP003646569 RP003648694 RP003650491 RP003652877 RP003656502 RP003659444 RP003662254 RP003677154
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0039066 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42749
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: EloA CG6755 (Gerber et al., 2004)
Source for database merge of
Additional comments
Other Comments
	Shows particularly robust cycling of transcription in adult heads, as assessed by expression analysis using high density oligonucleotide arrays with probe generated during three 12-point time course experiments over the course of 6 days. (Claridge-Chang et al., 2001)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_142878 NM_170061 RefSeq (Proteins) • NP_651135 NP_732846 DDBJ / EMBL / GenBank • AA201913 AA950135 AAF56117 AAL28911 AAN13934 AW942902 AY061363 BI231278 Entrez Gene - A searchable database of RefSeq genes. • 42749 UniProtKB/Swiss-Prot • Q9VCP0
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • RNA polymerase II transcription factor SIII, subunit A (IPR010684) Transcription factor IIS, N-terminal (IPR017923)
Linkouts
	BioGRID - A database of protein and genetic interactions • 67692 DroID - A comprehensive database of gene and protein interactions. • FBgn0039066 DRSC - Results from RNAi screens. • FBgn0039066 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039066 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6755-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0039066 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42749 InParanoid A subset of ortholog calls from InParanoid. • AAEL010723-PA Aedes aegypti (mosquito) XP_396851.3 Apis mellifera (honey bee) XP_001944769.1 Acyrthosiphon pisum (pea aphid) 89229 Branchiostoma floridae (lancelet) BGIBMGA006506-PA Bombyx mori (silk worm) CN04710 Caenorhabditis brenneri (small nematode) CBP11615 Caenorhabditis briggsae (nematode) CE01611 Caenorhabditis elegans (worm) ENSCAFP00000019484 Canis familiaris (dog) ENSCINP00000008547 Ciona intestinalis (sea squirt) JA03534 Caenorhabditis japonica (nematode) CPIJ003427 Culex pipens (mosquito) ENSCPOP00000007754 Cavia porcellus (guinea pig) RP23940 Caenorhabditis remanei (nematode) 220355 Capitella spl (polychaete worm) 221473 Daphnia pulex (daphnia) ENSDARP00000027752 Danio rerio (zebra fish) ENSECAP00000015945 Equus caballus (horse) ENSGACP00000002713 Gymnopilus aculeatus (mushroom) ENSGALP00000034307 Gallus gallus (chicken) ENSP00000363662 Homo sapiens (human) ISCW007299-PA Ixodes scapularis (deer tick) 171838 Lottia gigantea (owl limpet) ENSMODP00000016070 Monodelphis domestica (gray opossum) ENSMMUP00000004240 Macaca mulatta (rhesus monkey) ENSMUSP00000030427 Mus musculus (house mouse) 199556 Nematostella vectensis (starlet anemone) XP_001607275.1 Nasonia vitripennis (wasp) ENSOANP00000008726 Ornithorynchus anatinus (platypus) ENSORLP00000012323 Oryzias latipes (japanese killifish) LOC_Os11g06650.1 Oryza sativa (asian rice) PHUM006929-PA Pediculus humanus (human body louse) PP27394 Pristionchus pacificus (nematode) ENSPPYP00000002009 Pongo pygmaeus (orangutan) ENSPTRP00000000585 Pan troglodytes (chimpanzee) ENSRNOP00000015649 Rattus norvegicus (norway rat) Smp_143350 Schistosoma mansoni (trematode parasite) XP_797640.2 Strongylocentrotus purpuratus (purple sea urchin) XP_966848.1 Tribolium castaneum (red flour beetle) ENSTNIP00000019663 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000009784 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000046737 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42749 modMine - Data generated by the modENCODE project. • FBgn0039066 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV14080 LH22664 ISCW007299 FBgn0228229 FBgn0216065 FBgn0211451 FBgn0192463 FBgn0181347 JGI_V11_221473 FBgn0079833 FBgn0162080 FBgn0147084 FBgn0125983 FBgn0103496 FBgn0094005 CPIJ003427 BGIBMGA006506 ACYPI006169 GB12764 AGAP004363 AAEL010723 PB21793 PHUM128980 GLEAN_01477
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	CG6755 (Gerber et al., 2004, Claridge-Chang et al., 2001, Giot et al., 2003, Molnar et al., 2006, Gandhi et al., 2007, Keleman et al., 2009.8.5) dEloA (Gerber et al., 2005, Gerber et al., 2004, Tenney et al., 2006) EloA (Tenney et al., 2006) Elo-A (Chopra et al., 2009)
Name Synonym	Elongin A (Gerber et al., 2004, Eissenberg et al., 2007, Chopra and Levine, 2008) Elongin-A (Chopra et al., 2009)
Secondary FlyBase IDs
References ( 22 )
Generate a list of	All references relating to this gene ( 22 )
List References by type	Research paper  ( 7 ) Supplementary material  ( 4 ) Personal communication to FlyBase  ( 5 ) Abstract  ( 1 ) FlyBase analysis  ( 1 ) Protein sequence record  ( 1 ) Computer file  ( 1 ) Automatic genome annotation  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2010 Show research papers ...