Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.47
There is only one protein coding transcript and one polypeptide associated with this gene
In the active form, heterodimer of a light chain and a heavy chain; disulfide-linked.
Proteolytically cleaved in response to Gram-negative bacterial or fungal infection; processing is likely to result in its activation (PubMed:16399077). Cleavage produces a light chain containing the CLIP domain and a catalytic heavy chain which remain covalently associated through an interchain disulfide bond (Probable).
The clip domain consists of 35-55 residues which are 'knitted' together usually by 3 conserved disulfide bonds forming a clip-like compact structure.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\SPE using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\SPE in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.