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Gene Dmel\Nup98-96

General Information
Symbol	Dmel\Nup98-96	Species	D. melanogaster
Name	Nucleoporin 98-96	Annotation symbol	CG10198
Feature type	protein_coding_gene	FlyBase ID	FBgn0039120
Gene Model Status	Current	Stock availability	5 publicly available
Also Known As	Nup98, Nup96, l(3)95BCd
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	95B1-95B5	Sequence location	3R:19,599,947..19,607,366 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Nucleoporin 98-96 is referred to in FlyBase by the symbol Dmel\Nup98-96 (CG10198, FBgn0039120). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: germ-line stem cell maintenance; SMAD protein import into nucleus; phagocytosis, engulfment. 14 alleles are reported. The phenotypes of these alleles are annotated with: female fusome; nurse cell spectrosome; male germline cell. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Nuclear protein 96; Peptidase S59, nucleoporin. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval salivary gland, larval trachea, adult ovary, adult testis, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1632194_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Nup98. Gene sequence location is 3R:19599947..19607366.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10	References Parrott et al., 2011, PLoS ONE 6(9): e25087
FB2012_01	Transgenic Constructs P{UAS-Nup98-96.P} P{UAS-Nup98.P} Controlled Vocabulary Terms germ-line stem cell maintenance Insertions pogo{}Nup98-96[2288] Alleles Nup98-96[Scer\UAS.cPa] Nup98-96[2288] Nup98-96[Scer\UAS.98] Sequence features HFA14209 HFA14210 BKN20484
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 95B1-95B5   Limits computationally determined from genome sequence between P{PZ}l(3)0468404684 and P{PZ}Atg600096
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Nup98-96 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	The larger Nup98-RA transcript encodes a single, large precursor polyprotein that, in other eukaryotes, and thus presumably in flies, autoproteolytically cleaves itself between residues Phe1028 and Ser1029, yielding separate Nup98 and Nup96 proteins (FBrf0159638). Gene model reviewed during 5.41
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Nup98-96-RA FBtr0084460  NM_142930   6647   1960 Nup98-96-RC FBtr0304567     3987   1179
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Nup98-96-PA   FBpp0083851   210.1   1960   6.50     NP_651187   AAF56190 Nup98-96-PC   FBpp0293109   121.6   1179   6.47
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Peptidase S59, nucleoporin (IPR007230) Nuclear protein 96 (IPR021967)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA390577   AA390606   AA392158   AA438836   AA440511   AA539270   AA694787   AA696859   AA801555   AA820976   AA941772   AA950532   AA950681   AE014297 AAF56190   AI456395   AI515774   AI515795   AI516387   AI519590   AI532857   AI542148   AI542372   AI546649   AW944554   AY250769 AAP13264   AY250770 AAP13266   AY250771 AAP13265   AY250772 AAP13267   AY250773 AAP13268   AY250774 AAP13269   AY250775 AAP13270   AY250776 AAP13271   AY250777 AAP13272   AY250778 AAP13273   AY250779 AAP13274   AY250780 AAP13275   AY250781 AAP13276   AY250782 AAP13277   AY250783 AAP13278   BF485591   BF486166   BF490143   BF493028   BF493029   BF498191   BF504079   BF505261   BF505742   BG638180   BG639010   BI230973   BI352015   BI370332   BT011076   BT056313   CK658004   CO153502   CO155990   CO189209   CO272942   CO275618   CO279924   CO294275   CO336996   CO338515   CO338630   EC059908   EC200257   EC216430   EC229819   EC235921   EC243792   EC261686   EC261809   EC266939   EC267568   EF057947 ABL84882   EF057948 ABL84883   EF057949 ABL84884   EF057950 ABL84885   EF057951 ABL84886   EF057952 ABL84887   EF057953 ABL84888   EF057954 ABL84889   EF057955 ABL84890   EF057956 ABL84891   EF057957 ABL84892   EF057958 ABL84893   EF057959 ABL84894   EF057960 ABL84895   EF057961 ABL84896   EL882236   EL882237   ES690236   GH738854   GH774023   GH777462   GH813174   GH847315
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q867H5 Q867M2 Q867M7 Q867W7 Q868A8 Q86G43 Q9VCH5 A1YK27 A1YK24 A1YK38 A1YK25 A1YK33 A1YK35 A1YK36
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0039120    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0039120 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0039120 expression level Developmental Stage   Expression Level embryo 00-02hr    5145 embryo 02-04hr    3831 embryo 04-06hr    4946 embryo 06-08hr    3703 embryo 08-10hr    2944 embryo 10-12hr    1618 embryo 12-14hr    1596 embryo 14-16hr    1285 embryo 16-18hr    1007 embryo 18-20hr    647 embryo 20-22hr    798 embryo 22-24hr    822 larva L1    1229 larva L2    1130 larva L3 12hr old    921 larva L3 puffstage 1-2    760 larva L3 puffstage 3-6    1193 larva L3 puffstage 7-9    1290 white prepupae new    1259 white prepupae 12hr    1407 white prepupae 24hr    1657 pupae 2d postWPP    1093 pupae 3d postWPP    675 pupae 4d postWPP    678 adult male 01day    840 adult male 05day    1208 adult male 30day    1074 adult female 01day    1710 adult female 05day    3412 adult female 30day    3380 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (5145) embryo 02-04hr  (3831) embryo 04-06hr  (4946) embryo 06-08hr  (3703) embryo 08-10hr  (2944) embryo 10-12hr  (1618) embryo 12-14hr  (1596) embryo 14-16hr  (1285) embryo 16-18hr  (1007) embryo 18-20hr  (647) embryo 20-22hr  (798) embryo 22-24hr  (822) larva L1  (1229) larva L2  (1130) larva L3 12hr old  (921) larva L3 puffstage 1-2  (760) larva L3 puffstage 3-6  (1193) larva L3 puffstage 7-9  (1290) white prepupae new  (1259) white prepupae 12hr  (1407) white prepupae 24hr  (1657) pupae 2d postWPP  (1093) pupae 3d postWPP  (675) pupae 4d postWPP  (678) adult male 01day  (840) adult male 05day  (1208) adult male 30day  (1074) adult female 01day  (1710) adult female 05day  (3412) adult female 30day  (3380) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (5145) embryo 02-04hr  (3831) embryo 04-06hr  (4946) embryo 06-08hr  (3703) embryo 08-10hr  (2944) embryo 10-12hr  (1618) embryo 12-14hr  (1596) embryo 14-16hr    1285 embryo 16-18hr    1007 embryo 18-20hr    647 embryo 20-22hr    798 embryo 22-24hr    822 larva L1    1229 larva L2    1130 larva L3 12hr old    921 larva L3 puffstage 1-2    760 larva L3 puffstage 3-6    1193 larva L3 puffstage 7-9    1290 white prepupae new    1259 white prepupae 12hr  1407 white prepupae 24hr  (1657) pupae 2d postWPP    1093 pupae 3d postWPP    675 pupae 4d postWPP    678 adult male 01day    840 adult male 05day    1208 adult male 30day    1074 adult female 01day  (1710) adult female 05day  (3412) adult female 30day  (3380) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5145 embryo 02-04hr    3831 embryo 04-06hr    4946 embryo 06-08hr    3703 embryo 08-10hr    2944 embryo 10-12hr    1618 embryo 12-14hr    1596 embryo 14-16hr    1285 embryo 16-18hr    1007 embryo 18-20hr    647 embryo 20-22hr    798 embryo 22-24hr    822 larva L1    1229 larva L2    1130 larva L3 12hr old    921 larva L3 puffstage 1-2    760 larva L3 puffstage 3-6    1193 larva L3 puffstage 7-9    1290 white prepupae new    1259 white prepupae 12hr    1407 white prepupae 24hr    1657 pupae 2d postWPP    1093 pupae 3d postWPP    675 pupae 4d postWPP    678 adult male 01day    840 adult male 05day    1208 adult male 30day    1074 adult female 01day    1710 adult female 05day    3412 adult female 30day    3380 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5145 embryo 02-04hr    3831 embryo 04-06hr    4946 embryo 06-08hr    3703 embryo 08-10hr    2944 embryo 10-12hr    1618 embryo 12-14hr    1596 embryo 14-16hr    1285 embryo 16-18hr    1007 embryo 18-20hr    647 embryo 20-22hr    798 embryo 22-24hr    822 larva L1    1229 larva L2    1130 larva L3 12hr old    921 larva L3 puffstage 1-2    760 larva L3 puffstage 3-6    1193 larva L3 puffstage 7-9    1290 white prepupae new    1259 white prepupae 12hr    1407 white prepupae 24hr    1657 pupae 2d postWPP    1093 pupae 3d postWPP    675 pupae 4d postWPP    678 adult male 01day    840 adult male 05day    1208 adult male 30day    1074 adult female 01day    1710 adult female 05day    3412 adult female 30day    3380 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0039120 expression level Developmental Stage   Expression Level embryo 00-02hr    5145 embryo 02-04hr    3831 embryo 04-06hr    4946 embryo 06-08hr    3703 embryo 08-10hr    2944 embryo 10-12hr    1618 embryo 12-14hr    1596 embryo 14-16hr    1285 embryo 16-18hr    1007 embryo 18-20hr    647 embryo 20-22hr    798 embryo 22-24hr    822 larva L1    1229 larva L2    1130 larva L3 12hr old    921 larva L3 puffstage 1-2    760 larva L3 puffstage 3-6    1193 larva L3 puffstage 7-9    1290 white prepupae new    1259 white prepupae 12hr    1407 white prepupae 24hr    1657 pupae 2d postWPP    1093 pupae 3d postWPP    675 pupae 4d postWPP    678 adult male 01day    840 adult male 05day    1208 adult male 30day    1074 adult female 01day    1710 adult female 05day    3412 adult female 30day    3380 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (5145) embryo 02-04hr  (3831) embryo 04-06hr  (4946) embryo 06-08hr  (3703) embryo 08-10hr  (2944) embryo 10-12hr  (1618) embryo 12-14hr  (1596) embryo 14-16hr  (1285) embryo 16-18hr  (1007) embryo 18-20hr  (647) embryo 20-22hr  (798) embryo 22-24hr  (822) larva L1  (1229) larva L2  (1130) larva L3 12hr old  (921) larva L3 puffstage 1-2  (760) larva L3 puffstage 3-6  (1193) larva L3 puffstage 7-9  (1290) white prepupae new  (1259) white prepupae 12hr  (1407) white prepupae 24hr  (1657) pupae 2d postWPP  (1093) pupae 3d postWPP  (675) pupae 4d postWPP  (678) adult male 01day  (840) adult male 05day  (1208) adult male 30day  (1074) adult female 01day  (1710) adult female 05day  (3412) adult female 30day  (3380) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (5145) embryo 02-04hr  (3831) embryo 04-06hr  (4946) embryo 06-08hr  (3703) embryo 08-10hr  (2944) embryo 10-12hr  1618 embryo 12-14hr  1596 embryo 14-16hr    1285 embryo 16-18hr    1007 embryo 18-20hr    647 embryo 20-22hr    798 embryo 22-24hr    822 larva L1    1229 larva L2    1130 larva L3 12hr old    921 larva L3 puffstage 1-2    760 larva L3 puffstage 3-6    1193 larva L3 puffstage 7-9    1290 white prepupae new    1259 white prepupae 12hr  1407 white prepupae 24hr  1657 pupae 2d postWPP    1093 pupae 3d postWPP    675 pupae 4d postWPP    678 adult male 01day    840 adult male 05day    1208 adult male 30day    1074 adult female 01day  1710 adult female 05day  (3412) adult female 30day  (3380) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5145 embryo 02-04hr    3831 embryo 04-06hr    4946 embryo 06-08hr    3703 embryo 08-10hr    2944 embryo 10-12hr    1618 embryo 12-14hr    1596 embryo 14-16hr    1285 embryo 16-18hr    1007 embryo 18-20hr    647 embryo 20-22hr    798 embryo 22-24hr    822 larva L1    1229 larva L2    1130 larva L3 12hr old    921 larva L3 puffstage 1-2    760 larva L3 puffstage 3-6    1193 larva L3 puffstage 7-9    1290 white prepupae new    1259 white prepupae 12hr    1407 white prepupae 24hr    1657 pupae 2d postWPP    1093 pupae 3d postWPP    675 pupae 4d postWPP    678 adult male 01day    840 adult male 05day    1208 adult male 30day    1074 adult female 01day    1710 adult female 05day    3412 adult female 30day    3380 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5145 embryo 02-04hr    3831 embryo 04-06hr    4946 embryo 06-08hr    3703 embryo 08-10hr    2944 embryo 10-12hr    1618 embryo 12-14hr    1596 embryo 14-16hr    1285 embryo 16-18hr    1007 embryo 18-20hr    647 embryo 20-22hr    798 embryo 22-24hr    822 larva L1    1229 larva L2    1130 larva L3 12hr old    921 larva L3 puffstage 1-2    760 larva L3 puffstage 3-6    1193 larva L3 puffstage 7-9    1290 white prepupae new    1259 white prepupae 12hr    1407 white prepupae 24hr    1657 pupae 2d postWPP    1093 pupae 3d postWPP    675 pupae 4d postWPP    678 adult male 01day    840 adult male 05day    1208 adult male 30day    1074 adult female 01day    1710 adult female 05day    3412 adult female 30day    3380 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0039120    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0039120 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval salivary gland, larval trachea, adult ovary, adult testis, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0039120 expression level Tissue   Expression Level Larval Central Nervous System    218.075 Larval Midgut no informative data Larval Hindgut    89.2 Larval Malpighian Tubules    57.3 Larval Fat Body    67.2 Larval Salivary Gland    113.8 Larval Trachea    147.85 Larval Carcass    105.3 Adult Head    41.9 Adult Eye    31.525 Adult Brain    64.6 Adult Thoracic-Abdominal Ganglion    57.2 Adult Crop    44.6 Adult Midgut no informative data Adult Hindgut    50.9 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    32.875 Adult VirginFemale Spermatheca    34.5 Adult InseminatedFemale Spermatheca    43.1 Adult Ovary    277.2 Adult Testis    120.5 Adult Male Accessory Gland    67.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    218.075 Larval Midgut no informative data Larval Hindgut    89.2 Larval Malpighian Tubules    57.3 Larval Fat Body    67.2 Larval Salivary Gland    113.8 Larval Trachea    147.85 Larval Carcass    105.3 Adult Head    41.9 Adult Eye    31.525 Adult Brain    64.6 Adult Thoracic-Abdominal Ganglion    57.2 Adult Crop    44.6 Adult Midgut no informative data Adult Hindgut    50.9 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    32.875 Adult VirginFemale Spermatheca    34.5 Adult InseminatedFemale Spermatheca    43.1 Adult Ovary    277.2 Adult Testis    120.5 Adult Male Accessory Gland    67.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    218.075 Larval Midgut no informative data Larval Hindgut    89.2 Larval Malpighian Tubules    57.3 Larval Fat Body    67.2 Larval Salivary Gland    113.8 Larval Trachea    147.85 Larval Carcass    105.3 Adult Head    41.9 Adult Eye    31.525 Adult Brain    64.6 Adult Thoracic-Abdominal Ganglion    57.2 Adult Crop    44.6 Adult Midgut no informative data Adult Hindgut    50.9 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    32.875 Adult VirginFemale Spermatheca    34.5 Adult InseminatedFemale Spermatheca    43.1 Adult Ovary    277.2 Adult Testis    120.5 Adult Male Accessory Gland    67.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    218.075 Larval Midgut no informative data Larval Hindgut    89.2 Larval Malpighian Tubules    57.3 Larval Fat Body    67.2 Larval Salivary Gland    113.8 Larval Trachea    147.85 Larval Carcass    105.3 Adult Head    41.9 Adult Eye    31.525 Adult Brain    64.6 Adult Thoracic-Abdominal Ganglion    57.2 Adult Crop    44.6 Adult Midgut no informative data Adult Hindgut    50.9 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    32.875 Adult VirginFemale Spermatheca    34.5 Adult InseminatedFemale Spermatheca    43.1 Adult Ovary    277.2 Adult Testis    120.5 Adult Male Accessory Gland    67.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0039120 expression level Tissue   Expression Level Larval Central Nervous System    218.075 Larval Midgut no informative data Larval Hindgut    89.2 Larval Malpighian Tubules    57.3 Larval Fat Body    67.2 Larval Salivary Gland    113.8 Larval Trachea    147.85 Larval Carcass    105.3 Adult Head    41.9 Adult Eye    31.525 Adult Brain    64.6 Adult Thoracic-Abdominal Ganglion    57.2 Adult Crop    44.6 Adult Midgut no informative data Adult Hindgut    50.9 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    32.875 Adult VirginFemale Spermatheca    34.5 Adult InseminatedFemale Spermatheca    43.1 Adult Ovary    277.2 Adult Testis    120.5 Adult Male Accessory Gland    67.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    218.075 Larval Midgut no informative data Larval Hindgut    89.2 Larval Malpighian Tubules    57.3 Larval Fat Body    67.2 Larval Salivary Gland    113.8 Larval Trachea    147.85 Larval Carcass    105.3 Adult Head    41.9 Adult Eye    31.525 Adult Brain    64.6 Adult Thoracic-Abdominal Ganglion    57.2 Adult Crop    44.6 Adult Midgut no informative data Adult Hindgut    50.9 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    32.875 Adult VirginFemale Spermatheca    34.5 Adult InseminatedFemale Spermatheca    43.1 Adult Ovary    277.2 Adult Testis    120.5 Adult Male Accessory Gland    67.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    218.075 Larval Midgut no informative data Larval Hindgut    89.2 Larval Malpighian Tubules    57.3 Larval Fat Body    67.2 Larval Salivary Gland    113.8 Larval Trachea    147.85 Larval Carcass    105.3 Adult Head    41.9 Adult Eye    31.525 Adult Brain    64.6 Adult Thoracic-Abdominal Ganglion    57.2 Adult Crop    44.6 Adult Midgut no informative data Adult Hindgut    50.9 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    32.875 Adult VirginFemale Spermatheca    34.5 Adult InseminatedFemale Spermatheca    43.1 Adult Ovary    277.2 Adult Testis    120.5 Adult Male Accessory Gland    67.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    218.075 Larval Midgut no informative data Larval Hindgut    89.2 Larval Malpighian Tubules    57.3 Larval Fat Body    67.2 Larval Salivary Gland    113.8 Larval Trachea    147.85 Larval Carcass    105.3 Adult Head    41.9 Adult Eye    31.525 Adult Brain    64.6 Adult Thoracic-Abdominal Ganglion    57.2 Adult Crop    44.6 Adult Midgut no informative data Adult Hindgut    50.9 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    32.875 Adult VirginFemale Spermatheca    34.5 Adult InseminatedFemale Spermatheca    43.1 Adult Ovary    277.2 Adult Testis    120.5 Adult Male Accessory Gland    67.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut no informative data Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut no informative data Adult Hindgut     Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    41.9   NA  Eye    31.525   NA  Brain    64.6   218.075  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    57.2   NA  Crop    44.6   no informative data  Midgut    no informative data   89.2  Hindgut    50.9   57.3  Malpighian Tubules    no informative data   67.2  Fat Body    no informative data   113.8  Salivary Gland    no informative data   NA  Heart    32.875   147.85  Trachea    NA   NA  VirginFemale Spermatheca    34.5   NA  InseminatedFemale Spermatheca    43.1   NA  Ovary    277.2   NA  Testis    120.5   NA  Male Accessory Gland    67.6   105.3  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_13
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039120 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10198-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4pnr-MD237 Nup98-96GD6897 lethal | recessive Nup98-96339 Other Phenotypes Allele cell growth defective Nup98-96dsRNA.cMa Phenotype manifest in Allele female fusome Nup98-962288 female fusome (with Df(3R)mbc-R1) Nup98-962288 female germline cell | adult stage (with Df(3R)mbc-R1) Nup98-962288 male fusome | adult stage (with Df(3R)mbc-R1) Nup98-962288 male fusome | third instar larval stage (with Df(3R)mbc-R1) Nup98-962288 male germline cell, with Scer\GAL4nos.UTR.T:Hsim\VP16 Nup98-96GD6897 male germline cell | adult stage (with Df(3R)mbc-R1) Nup98-962288 male germline stem cell | third instar larval stage (with Df(3R)mbc-R1) Nup98-962288 nurse cell spectrosome Nup98-962288 nurse cell spectrosome (with Df(3R)mbc-R1) Nup98-962288 primary gonial cell | third instar larval stage (with Df(3R)mbc-R1) Nup98-962288 spermatogonium | third instar larval stage (with Df(3R)mbc-R1) Nup98-962288
Classical Alleles ( 8 )
For All Classical Alleles Show
Allele of Nup98-96 Class Mutagen Stocks Known lesion Nup98-96339 1 Yes Nup98-96G2120 P-element activity 1 -- Nup98-962288 0 Yes Nup98-96C14.7 0 -- Nup98-96E53.1 0 Yes Nup98-96F1.13 0 Yes Nup98-96F1.15 0 Yes Nup98-96F8.5 0 Yes
Alleles Carried on Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Nup98-96 Class Mutagen Stocks Known lesion Nup98-96GD6897 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes Nup98-96HM05048 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Nup98-96dsRNA.cMa in vitro construct - RNAi 0 Yes Nup98-96KK100388 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes Nup98-96Scer\UAS.98 in vitro construct - deletion 0 Yes Nup98-96Scer\UAS.cPa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)CA15 (Erickson et al., 1997) Df(3R)Exel9013 (Ryder, 2004.4.26) Df(3R)Exel9014 (Ryder, 2004.4.26) Df(3R)mbc-15A (Presgraves et al., 2003, Erickson et al., 1997) Df(3R)mbc-30 (Keller et al., 1998, Presgraves et al., 2003, Erickson et al., 1997, Parrott et al., 2011) Df(3R)mbc-BG1 (Presgraves et al., 2003) Df(3R)mbc-F5.3 (Presgraves et al., 2003, Erickson et al., 1997) Df(3R)mbc-R1 (Presgraves et al., 2003, Parrott et al., 2011) Df(3R)mbc-R.1 (Erickson et al., 1997) Df(3R)nau-9 (Keller et al., 1998, Presgraves et al., 2003) Df(3R)γ20 (Keller et al., 1998)
Not disrupted in	Df(3R)CA (Keller et al., 1998, Presgraves et al., 2003) Df(3R)CA2 (Erickson et al., 1997) Df(3R)nau-4A (Keller et al., 1998, Presgraves et al., 2003) Df(3R)nau-11a4 (Keller et al., 1998, Presgraves et al., 2003)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{UAS-Nup98-96.P} NA P{UAS-Nup98.P} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}Nup98-96G2120 NA miscellaneous insertions pogo{}Nup98-962288 NA
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 3 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
germ-line stem cell maintenance inferred from mutant phenotype (Parrott et al., 2011) phagocytosis, engulfment inferred from mutant phenotype (Stroschein-Stevenson et al., 2006) SMAD protein import into nucleus inferred from mutant phenotype (Chen and Xu, 2010)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
nuclear pore inferred from sequence or structural similarity with EMBL:AF071076 AND inferred from sequence or structural similarity with UniProtKB:P49793 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Nup98-96 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 67753 DroID - A comprehensive database of gene and protein interactions. • FBgn0039120 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42816
Orthologs
Genome-wide drosophilid orthologs	Dana\GF18736 Dere\GG12402 Dgri\GH10992 Dmoj\GI24505 Dper\GL24268 Dpse\GA10149 Dsec\GM23537 Dsim\Nup98 Dvir\GJ24642 Dwil\GK13519 Dyak\GE23921
Curated drosophilid orthologs	Dmau\Nup98   Dpse\GA10149   Dsim\Nup98   Dyak\GE23921
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL007586-PA Aedes aegypti (mosquito) AGAP002351-PA Anopheles gambiae (mosquito) XP_001943615.1 Acyrthosiphon pisum (pea aphid) At1g10390.1 Arabidopsis thaliana (wall cress) 86195 Batrachochytrium dendrobatidis (chytrid fungus) 117134 Branchiostoma floridae (lancelet) 117137 Branchiostoma floridae (lancelet) BGIBMGA001818-PA Bombyx mori (silk worm) ENSBTAP00000011092 Bos taurus (bovine) CAL0005513 Candida albicans (a form of yeast) CN05740 Caenorhabditis brenneri (small nematode) CBP33864 Caenorhabditis briggsae (nematode) CE34448 Caenorhabditis elegans (worm) ENSCAFP00000008797 Canis familiaris (dog) CAGL0H03069g Candida glabrata (haploid yeast) JA09550 Caenorhabditis japonica (nematode) CMB112C Cyanidioschyzon merolae (red alga) cn02461 Cryptococcus neoformans (yeast-like fungus) cgd3_2360 Cryptosporidium parvum (protozoan parasite) CPIJ002761 Culex pipens (mosquito) ENSCPOP00000005856 Cavia porcellus (guinea pig) RP37348 Caenorhabditis remanei (nematode) 222010 Capitella spl (polychaete worm) DDB0235244 Dictyostelium discoideum (amoeba) DEHA2C14696g Debaryomyces Hansenii (yeast) 198208 Daphnia pulex (daphnia) ENSDARP00000071337 Danio rerio (zebra fish) ENSECAP00000013468 Equus caballus (horse) ENSGACP00000002533 Gymnopilus aculeatus (mushroom) ENSGALP00000022023 Gallus gallus (chicken) 191188 Hypsipyla robusta (cedar shoot borer) ENSP00000316032 Homo sapiens (human) ISCW013985-PA Ixodes scapularis (deer tick) KLLA0F26697g Kluyveromyces lactis (yeast) LmjF27.0380 Leishmania major (virus) 34592 Monocosta brevicollis (choanoflagellate) ENSMODP00000010305 Monodelphis domestica (gray opossum) ENSMMUP00000005278 Macaca mulatta (rhesus monkey) ENSMUSP00000094405 Mus musculus (house mouse) 103213 Nematostella vectensis (starlet anemone) ENSOANP00000008201 Ornithorynchus anatinus (platypus) LOC_Os12g06870.1 Oryza sativa (asian rice) PHUM002393-PA Pediculus humanus (human body louse) PP17057 Pristionchus pacificus (nematode) ENSPPYP00000004152 Pongo pygmaeus (orangutan) 73295 Phytophthora ramorum (sudden oak death pathogen) 131301 Phytophthora sojae (root rot pathogen) 554860 Populus trichocarpa (black cottonwood) ENSPTRP00000041699 Pan troglodytes (chimpanzee) PVX_100825 Plasmodium vivax (protozoal parasite) ENSRNOP00000027546 Rattus norvegicus (norway rat) 5057408 Sorghum bicolor (sorghum) YGL092W Saccharomyces cerevisiae (budding yeast) Smp_027890 Schistosoma mansoni (trematode parasite) SPAC1486.05 Schizosaccharomyces pombe (fission yeast) XP_001190561.1 Strongylocentrotus purpuratus (purple sea urchin) 56476 Trichoplax adhaerens (metazoa) XP_968362.1 Tribolium castaneum (red flour beetle) ENSTNIP00000010498 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000006218 Takifugu rubripes (pufferfish Takifugu) 3684.m00120 Tetrahymena thermophila (ciliate protozoa) YALI0F28281g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV24349 NV23669 NV17085 LH14813 ISCW013985 ISCW003758 FBgn0066139 FBgn0215527 FBgn0211719 FBgn0066160 FBgn0178403 JGI_V11_120178 JGI_V11_198208 JGI_V11_118557 FBgn0070208 FBgn0161858 FBgn0147227 FBgn0118473 FBgn0104690 FBgn0095753 CPIJ002761 BGIBMGA001818 ACYPI53840 ACYPI007866 ACYPI001279 GB12688 AGAP002351 AAEL013293 AAEL007586 AAEL004394 PB24904 PHUM598450 GLEAN_13629
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	4951 Nup98-96339/TM3, Sb1 28562 y1 v1; P{TRiP.HM05048}attP2 28433 y1 w*; P{EP}Nup98-96G2120/TM3, Sb1 Ser1
VDRC	v31198 w1118; P{GD6897}v31198 v31199 w1118; P{GD6897}v31199
Genomic Clones ( 1 )
	BACR11E07 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 62 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE74545 SD08263
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT05364 AT07449 AT08029 AT12565 AT19515 AT20377 AT26440 GM01543 GM08563 GM17245 HL06651 LD09476 LD09677 LD11041 LD13201 LD14529 LD24940 LD25956 LD30367 LD30635 LD36408 LD39229 LD41466 LD42241 LP14480 RE16647 RE56809 SD04491 SD08666 SD09825
Other clones	9848 58218 76588 194857 522478 527036 562055 572861 AT01311 CK01.53D.G7 CK01.141D.F4 EK043428 EK108924 EK118054 EK136409 EK206458 EN02115 EN07150 EN13628 EN17004 EN17229 IP11993 LD18952 LD41443 RC0-DA0007-130700-013-E07 RP01313 RP003117421 RP003126206 RP003215536 RP003639413
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0039120 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42816
Antibody Information
	polyclonal (Parrott et al., 2011)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG10198 CG10201 (FlyBase, 1996-) Source for merge of: l(3)95BCd Nup98 (Presgraves et al., 2003)
Additional comments	FlyBase Curator comment: Correspondence with author Lan Xu revealed that 'nup145' = CG10198. (Chen and Xu, 2010) Source for merge of CG10198 CG10201 was a shared cDNA (date:010720). (FlyBase, 1996-)
Other Comments
	S2 cells treated with dsRNA directed against Nup98 show decreased uptake of S.aureus by phagocytosis compared to control cells. (Stuart et al., 2007) S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells. (Stroschein-Stevenson et al., 2006) Identified as a potential component of the hh signalling pathway in a genome-wide RNAi screen. dsRNA made from templates generated with primers directed affects the extent of expression of a hh signaling reporter construct in Clone 8 cells. (Nybakken et al., 2005) This gene is alternatively transcribed, giving rise to a minor 3.5kb Nup98 transcript and a major 7.3kb Nup98-Nup96 transcript. Which may autoproteolytically cleaves itself yielding separate Nup98 and Nup96 proteins. (Presgraves et al., 2003) Nup98 causes epistatic inviability in hybrids between D.melanogaster and D.simulans. (Presgraves et al., 2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_142930 RefSeq (Proteins) • NP_651187 DDBJ / EMBL / GenBank • AAF56190 AAP13264 AAP13265 AAP13266 AAP13267 AAP13268 AAP13269 AAP13270 AAP13271 AAP13272 AAP13273 AAP13274 AAP13275 AAP13276 AAP13277 AAP13278 ABL84882 ABL84883 ABL84884 ABL84885 ABL84886 ABL84887 ABL84888 ABL84889 ABL84890 ABL84891 ABL84892 ABL84893 ABL84894 ABL84895 ABL84896 AI542148 AW944554 AY250769 AY250770 AY250771 AY250772 AY250773 AY250774 AY250775 AY250776 AY250777 AY250778 AY250779 AY250780 AY250781 AY250782 AY250783 EF057947 EF057948 EF057949 EF057950 EF057951 EF057952 EF057953 EF057954 EF057955 EF057956 EF057957 EF057958 EF057959 EF057960 EF057961 Entrez Gene - A searchable database of RefSeq genes. • 42816 UniProtKB/TrEMBL • A1YK24 A1YK25 A1YK27 A1YK33 A1YK35 A1YK36 A1YK38 Q9VCH5 Q86G43 Q867H5 Q867M2 Q867M7 Q867W7 Q868A8
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Peptidase S59, nucleoporin (IPR007230) Nuclear protein 96 (IPR021967)
Linkouts
	BioGRID - A database of protein and genetic interactions • 67753 DroID - A comprehensive database of gene and protein interactions. • FBgn0039120 DRSC - Results from RNAi screens. • FBgn0039120 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039120 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10198-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0039120 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42816 InParanoid A subset of ortholog calls from InParanoid. • AAEL007586-PA Aedes aegypti (mosquito) AGAP002351-PA Anopheles gambiae (mosquito) XP_001943615.1 Acyrthosiphon pisum (pea aphid) At1g10390.1 Arabidopsis thaliana (wall cress) 86195 Batrachochytrium dendrobatidis (chytrid fungus) 117134 Branchiostoma floridae (lancelet) 117137 Branchiostoma floridae (lancelet) BGIBMGA001818-PA Bombyx mori (silk worm) ENSBTAP00000011092 Bos taurus (bovine) CAL0005513 Candida albicans (a form of yeast) CN05740 Caenorhabditis brenneri (small nematode) CBP33864 Caenorhabditis briggsae (nematode) CE34448 Caenorhabditis elegans (worm) ENSCAFP00000008797 Canis familiaris (dog) CAGL0H03069g Candida glabrata (haploid yeast) JA09550 Caenorhabditis japonica (nematode) CMB112C Cyanidioschyzon merolae (red alga) cn02461 Cryptococcus neoformans (yeast-like fungus) cgd3_2360 Cryptosporidium parvum (protozoan parasite) CPIJ002761 Culex pipens (mosquito) ENSCPOP00000005856 Cavia porcellus (guinea pig) RP37348 Caenorhabditis remanei (nematode) 222010 Capitella spl (polychaete worm) DDB0235244 Dictyostelium discoideum (amoeba) DEHA2C14696g Debaryomyces Hansenii (yeast) 198208 Daphnia pulex (daphnia) ENSDARP00000071337 Danio rerio (zebra fish) ENSECAP00000013468 Equus caballus (horse) ENSGACP00000002533 Gymnopilus aculeatus (mushroom) ENSGALP00000022023 Gallus gallus (chicken) 191188 Hypsipyla robusta (cedar shoot borer) ENSP00000316032 Homo sapiens (human) ISCW013985-PA Ixodes scapularis (deer tick) KLLA0F26697g Kluyveromyces lactis (yeast) LmjF27.0380 Leishmania major (virus) 34592 Monocosta brevicollis (choanoflagellate) ENSMODP00000010305 Monodelphis domestica (gray opossum) ENSMMUP00000005278 Macaca mulatta (rhesus monkey) ENSMUSP00000094405 Mus musculus (house mouse) 103213 Nematostella vectensis (starlet anemone) ENSOANP00000008201 Ornithorynchus anatinus (platypus) LOC_Os12g06870.1 Oryza sativa (asian rice) PHUM002393-PA Pediculus humanus (human body louse) PP17057 Pristionchus pacificus (nematode) ENSPPYP00000004152 Pongo pygmaeus (orangutan) 73295 Phytophthora ramorum (sudden oak death pathogen) 131301 Phytophthora sojae (root rot pathogen) 554860 Populus trichocarpa (black cottonwood) ENSPTRP00000041699 Pan troglodytes (chimpanzee) PVX_100825 Plasmodium vivax (protozoal parasite) ENSRNOP00000027546 Rattus norvegicus (norway rat) 5057408 Sorghum bicolor (sorghum) YGL092W Saccharomyces cerevisiae (budding yeast) Smp_027890 Schistosoma mansoni (trematode parasite) SPAC1486.05 Schizosaccharomyces pombe (fission yeast) XP_001190561.1 Strongylocentrotus purpuratus (purple sea urchin) 56476 Trichoplax adhaerens (metazoa) XP_968362.1 Tribolium castaneum (red flour beetle) ENSTNIP00000010498 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000006218 Takifugu rubripes (pufferfish Takifugu) 3684.m00120 Tetrahymena thermophila (ciliate protozoa) YALI0F28281g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42816 modMine - Data generated by the modENCODE project. • FBgn0039120 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV24349 NV23669 NV17085 LH14813 ISCW013985 ISCW003758 FBgn0066139 FBgn0215527 FBgn0211719 FBgn0066160 FBgn0178403 JGI_V11_120178 JGI_V11_198208 JGI_V11_118557 FBgn0070208 FBgn0161858 FBgn0147227 FBgn0118473 FBgn0104690 FBgn0095753 CPIJ002761 BGIBMGA001818 ACYPI53840 ACYPI007866 ACYPI001279 GB12688 AGAP002351 AAEL013293 AAEL007586 AAEL004394 PB24904 PHUM598450 GLEAN_13629
Synonyms & Secondary IDs ( 15 )
Reported As
Symbol Synonym	CG10198 (Presgraves et al., 2003, Giot et al., 2003, Stuart et al., 2007, Nybakken et al., 2005, Perkins et al., 2009, Keleman et al., 2009.8.5) CG10201   l(3)95BCd (Bloomington Drosophila Stock Center, 1999.6.28, Keller et al., 1998, Erickson et al., 1997, ) Nup96 (Albert, 2005, Orr, 2005, Orr et al., 2004, Swanson, 2003, Presgraves et al., 2003, Presgraves and Stephan, 2007, Pennisi, 2006, Barbash, 2007, Capelson et al., 2010) Nup 96 (Clark and Aquadro, 2010) Nup98 (Finan et al., 2011, Mendjan et al., 2006, Presgraves and Stephan, 2007, Stroschein-Stevenson et al., 2006, Stuart et al., 2007, Nybakken et al., 2005, Baeg et al., 2007, Barbash, 2007, Doheny et al., 2008, Capelson et al., 2010, Kalverda et al., 2010) Nup 98 (Clark and Aquadro, 2010) Nup98-96   nup98-96 (Parrott et al., 2011) Nup98/96 (Sarkar et al., 2006) Nup98-Nup96 (Presgraves et al., 2003) nup145 (Chen and Xu, 2010)
Name Synonym	Nucleoporin 98   nucleoporin98-96 (Parrott et al., 2011) Nucleoporin 98-96   Nup98
Secondary FlyBase IDs
	FBgn0021781 FBgn0039119
References ( 41 )
Generate a list of	All references relating to this gene ( 41 )
List References by type	Research paper  ( 19 ) Supplementary material  ( 3 ) Review  ( 6 ) Erratum  ( 1 ) Personal communication to FlyBase  ( 6 ) Abstract  ( 1 ) FlyBase analysis  ( 2 ) Computer file  ( 1 ) Automatic genome annotation  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 6 )
	Finan et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(14): 5566--5571 From the Cover: Proteomics approach to study the functions of Drosophila myosin VI through identification of multiple cargo-binding proteins. [FBrf0213355] Parrott et al., 2011, PLoS ONE 6(9): e25087 Nucleoporin98-96 Function Is Required for Transit Amplification Divisions in the Germ Line of Drosophila melanogaster. [FBrf0216255] Capelson et al., 2010, Cell 140(3): 372--383 Chromatin-Bound Nuclear Pore Components Regulate Gene Expression in Higher Eukaryotes. [FBrf0209890] Chen and Xu, 2010, Mol. Cell. Biol. 30(16): 4022--4034 Specific nucleoporin requirement for smad nuclear translocation. [FBrf0211334] Clark and Aquadro, 2010, Mol. Biol. Evol. 27(5): 1152--1161 A novel method to detect proteins evolving at correlated rates: identifying new functional relationships between coevolving proteins. [FBrf0210693] Kalverda et al., 2010, Cell 140(3): 360--371 Nucleoporins Directly Stimulate Expression of Developmental and Cell-Cycle Genes Inside the Nucleoplasm. [FBrf0209913] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...