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Gene Dmel\CG6129

General Information
Symbol	Dmel\CG6129	Species	D. melanogaster
Name		Annotation symbol	CG6129
Feature type	protein_coding_gene	FlyBase ID	FBgn0039152
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	95E1-95E1	Sequence location	3R:19,939,317..19,953,915 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG6129 (FBgn0039152). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Protein of unknown function DUF827, plant. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 18-24 hour embryonic stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult fat body, adult spermathecae, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1634341_a_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG6129. Gene sequence location is 3R:19939317..19953915.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features HFA15972 BKN22275
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 95E1-95E1   Limits computationally determined from genome sequence between P{PZ}Syx1A06737&P{PZ}Syx1A10660 and P{PZ}crb07207&P{PZ}BRWD305842
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG6129 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	DGC clone AT16851 appears problematic: incomplete CDS
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG6129-RD FBtr0304161  NM_142959   6731   2048
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG6129-PD   FBpp0293091   232.7   2048   6.13     NP_651216   AAF56238
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Protein of unknown function DUF827, plant (IPR008545)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF56238   AY118691 AAM50551   BE975282   BF489448   BF490369   BF492365   BF493278   BF494230   BF495950   BF495951   BF497937   BF498622   BF501493   BF501584   BF501980   BF502257   BF502909   BF504351   BG631982   CK661653   CO334054   EY198849
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8MSN3 Q9VCD1
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 5 of adulthood & male -- day 7 of adulthood & male   spermatozoon   (Wasbrough et al., 2010)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0039152    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0039152 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 18-24 hour embryonic stages, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0039152 expression level Developmental Stage   Expression Level embryo 00-02hr    12 embryo 02-04hr    25 embryo 04-06hr    43 embryo 06-08hr    131 embryo 08-10hr    289 embryo 10-12hr    411 embryo 12-14hr    524 embryo 14-16hr    872 embryo 16-18hr    1199 embryo 18-20hr    1625 embryo 20-22hr    794 embryo 22-24hr    839 larva L1    349 larva L2    140 larva L3 12hr old    646 larva L3 puffstage 1-2    870 larva L3 puffstage 3-6    717 larva L3 puffstage 7-9    785 white prepupae new    867 white prepupae 12hr    687 white prepupae 24hr    1032 pupae 2d postWPP    1146 pupae 3d postWPP    1032 pupae 4d postWPP    825 adult male 01day    1496 adult male 05day    2135 adult male 30day    1979 adult female 01day    89 adult female 05day    158 adult female 30day    324 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    12 embryo 02-04hr    25 embryo 04-06hr    43 embryo 06-08hr  (131) embryo 08-10hr  (289) embryo 10-12hr  (411) embryo 12-14hr  (524) embryo 14-16hr  (872) embryo 16-18hr  (1199) embryo 18-20hr  (1625) embryo 20-22hr  (794) embryo 22-24hr  (839) larva L1  (349) larva L2  (140) larva L3 12hr old  (646) larva L3 puffstage 1-2  (870) larva L3 puffstage 3-6  (717) larva L3 puffstage 7-9  (785) white prepupae new  (867) white prepupae 12hr  (687) white prepupae 24hr  (1032) pupae 2d postWPP  (1146) pupae 3d postWPP  (1032) pupae 4d postWPP  (825) adult male 01day  (1496) adult male 05day  (2135) adult male 30day  (1979) adult female 01day    89 adult female 05day  (158) adult female 30day  (324) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    12 embryo 02-04hr    25 embryo 04-06hr    43 embryo 06-08hr    131 embryo 08-10hr    289 embryo 10-12hr    411 embryo 12-14hr    524 embryo 14-16hr    872 embryo 16-18hr    1199 embryo 18-20hr  (1625) embryo 20-22hr    794 embryo 22-24hr    839 larva L1    349 larva L2    140 larva L3 12hr old    646 larva L3 puffstage 1-2    870 larva L3 puffstage 3-6    717 larva L3 puffstage 7-9    785 white prepupae new    867 white prepupae 12hr    687 white prepupae 24hr    1032 pupae 2d postWPP    1146 pupae 3d postWPP    1032 pupae 4d postWPP    825 adult male 01day  1496 adult male 05day  (2135) adult male 30day  (1979) adult female 01day    89 adult female 05day    158 adult female 30day    324 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    12 embryo 02-04hr    25 embryo 04-06hr    43 embryo 06-08hr    131 embryo 08-10hr    289 embryo 10-12hr    411 embryo 12-14hr    524 embryo 14-16hr    872 embryo 16-18hr    1199 embryo 18-20hr    1625 embryo 20-22hr    794 embryo 22-24hr    839 larva L1    349 larva L2    140 larva L3 12hr old    646 larva L3 puffstage 1-2    870 larva L3 puffstage 3-6    717 larva L3 puffstage 7-9    785 white prepupae new    867 white prepupae 12hr    687 white prepupae 24hr    1032 pupae 2d postWPP    1146 pupae 3d postWPP    1032 pupae 4d postWPP    825 adult male 01day    1496 adult male 05day    2135 adult male 30day    1979 adult female 01day    89 adult female 05day    158 adult female 30day    324 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    12 embryo 02-04hr    25 embryo 04-06hr    43 embryo 06-08hr    131 embryo 08-10hr    289 embryo 10-12hr    411 embryo 12-14hr    524 embryo 14-16hr    872 embryo 16-18hr    1199 embryo 18-20hr    1625 embryo 20-22hr    794 embryo 22-24hr    839 larva L1    349 larva L2    140 larva L3 12hr old    646 larva L3 puffstage 1-2    870 larva L3 puffstage 3-6    717 larva L3 puffstage 7-9    785 white prepupae new    867 white prepupae 12hr    687 white prepupae 24hr    1032 pupae 2d postWPP    1146 pupae 3d postWPP    1032 pupae 4d postWPP    825 adult male 01day    1496 adult male 05day    2135 adult male 30day    1979 adult female 01day    89 adult female 05day    158 adult female 30day    324 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0039152 expression level Developmental Stage   Expression Level embryo 00-02hr    12 embryo 02-04hr    25 embryo 04-06hr    43 embryo 06-08hr    131 embryo 08-10hr    289 embryo 10-12hr    411 embryo 12-14hr    524 embryo 14-16hr    872 embryo 16-18hr    1199 embryo 18-20hr    1625 embryo 20-22hr    794 embryo 22-24hr    839 larva L1    349 larva L2    140 larva L3 12hr old    646 larva L3 puffstage 1-2    870 larva L3 puffstage 3-6    717 larva L3 puffstage 7-9    785 white prepupae new    867 white prepupae 12hr    687 white prepupae 24hr    1032 pupae 2d postWPP    1146 pupae 3d postWPP    1032 pupae 4d postWPP    825 adult male 01day    1496 adult male 05day    2135 adult male 30day    1979 adult female 01day    89 adult female 05day    158 adult female 30day    324 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    12 embryo 02-04hr    25 embryo 04-06hr    43 embryo 06-08hr  131 embryo 08-10hr  (289) embryo 10-12hr  (411) embryo 12-14hr  (524) embryo 14-16hr  (872) embryo 16-18hr  (1199) embryo 18-20hr  (1625) embryo 20-22hr  (794) embryo 22-24hr  (839) larva L1  (349) larva L2  140 larva L3 12hr old  (646) larva L3 puffstage 1-2  (870) larva L3 puffstage 3-6  (717) larva L3 puffstage 7-9  (785) white prepupae new  (867) white prepupae 12hr  (687) white prepupae 24hr  (1032) pupae 2d postWPP  (1146) pupae 3d postWPP  (1032) pupae 4d postWPP  (825) adult male 01day  (1496) adult male 05day  (2135) adult male 30day  (1979) adult female 01day    89 adult female 05day  (158) adult female 30day  (324) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    12 embryo 02-04hr    25 embryo 04-06hr    43 embryo 06-08hr    131 embryo 08-10hr    289 embryo 10-12hr    411 embryo 12-14hr    524 embryo 14-16hr    872 embryo 16-18hr    1199 embryo 18-20hr  1625 embryo 20-22hr    794 embryo 22-24hr    839 larva L1    349 larva L2    140 larva L3 12hr old    646 larva L3 puffstage 1-2    870 larva L3 puffstage 3-6    717 larva L3 puffstage 7-9    785 white prepupae new    867 white prepupae 12hr    687 white prepupae 24hr    1032 pupae 2d postWPP    1146 pupae 3d postWPP    1032 pupae 4d postWPP    825 adult male 01day  1496 adult male 05day  2135 adult male 30day  1979 adult female 01day    89 adult female 05day    158 adult female 30day    324 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    12 embryo 02-04hr    25 embryo 04-06hr    43 embryo 06-08hr    131 embryo 08-10hr    289 embryo 10-12hr    411 embryo 12-14hr    524 embryo 14-16hr    872 embryo 16-18hr    1199 embryo 18-20hr    1625 embryo 20-22hr    794 embryo 22-24hr    839 larva L1    349 larva L2    140 larva L3 12hr old    646 larva L3 puffstage 1-2    870 larva L3 puffstage 3-6    717 larva L3 puffstage 7-9    785 white prepupae new    867 white prepupae 12hr    687 white prepupae 24hr    1032 pupae 2d postWPP    1146 pupae 3d postWPP    1032 pupae 4d postWPP    825 adult male 01day    1496 adult male 05day    2135 adult male 30day    1979 adult female 01day    89 adult female 05day    158 adult female 30day    324 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    12 embryo 02-04hr    25 embryo 04-06hr    43 embryo 06-08hr    131 embryo 08-10hr    289 embryo 10-12hr    411 embryo 12-14hr    524 embryo 14-16hr    872 embryo 16-18hr    1199 embryo 18-20hr    1625 embryo 20-22hr    794 embryo 22-24hr    839 larva L1    349 larva L2    140 larva L3 12hr old    646 larva L3 puffstage 1-2    870 larva L3 puffstage 3-6    717 larva L3 puffstage 7-9    785 white prepupae new    867 white prepupae 12hr    687 white prepupae 24hr    1032 pupae 2d postWPP    1146 pupae 3d postWPP    1032 pupae 4d postWPP    825 adult male 01day    1496 adult male 05day    2135 adult male 30day    1979 adult female 01day    89 adult female 05day    158 adult female 30day    324 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0039152    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0039152 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult fat body, adult spermathecae, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0039152 expression level Tissue   Expression Level Larval Central Nervous System    37.625 Larval Midgut    21.3 Larval Hindgut    4.8 Larval Malpighian Tubules    9.1 Larval Fat Body    486.4 Larval Salivary Gland    27.9 Larval Trachea    8.825 Larval Carcass no informative data Adult Head    55.9 Adult Eye    27.4 Adult Brain    6.2 Adult Thoracic-Abdominal Ganglion    8.7 Adult Crop    8.2 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules    8.2 Adult Fat Body    313.3 Adult Salivary Gland no informative data Adult Heart    80.025 Adult VirginFemale Spermatheca    130 Adult InseminatedFemale Spermatheca    390.6 Adult Ovary    6.3 Adult Testis    610 Adult Male Accessory Gland    9.8 Adult Carcass    102.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    37.625 Larval Midgut    21.3 Larval Hindgut    4.8 Larval Malpighian Tubules    9.1 Larval Fat Body    486.4 Larval Salivary Gland    27.9 Larval Trachea    8.825 Larval Carcass no informative data Adult Head    55.9 Adult Eye    27.4 Adult Brain    6.2 Adult Thoracic-Abdominal Ganglion    8.7 Adult Crop    8.2 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules    8.2 Adult Fat Body    313.3 Adult Salivary Gland no informative data Adult Heart    80.025 Adult VirginFemale Spermatheca    130 Adult InseminatedFemale Spermatheca    390.6 Adult Ovary    6.3 Adult Testis  (610) Adult Male Accessory Gland    9.8 Adult Carcass    102.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    37.625 Larval Midgut    21.3 Larval Hindgut    4.8 Larval Malpighian Tubules    9.1 Larval Fat Body    486.4 Larval Salivary Gland    27.9 Larval Trachea    8.825 Larval Carcass no informative data Adult Head    55.9 Adult Eye    27.4 Adult Brain    6.2 Adult Thoracic-Abdominal Ganglion    8.7 Adult Crop    8.2 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules    8.2 Adult Fat Body    313.3 Adult Salivary Gland no informative data Adult Heart    80.025 Adult VirginFemale Spermatheca    130 Adult InseminatedFemale Spermatheca    390.6 Adult Ovary    6.3 Adult Testis    610 Adult Male Accessory Gland    9.8 Adult Carcass    102.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    37.625 Larval Midgut    21.3 Larval Hindgut    4.8 Larval Malpighian Tubules    9.1 Larval Fat Body    486.4 Larval Salivary Gland    27.9 Larval Trachea    8.825 Larval Carcass no informative data Adult Head    55.9 Adult Eye    27.4 Adult Brain    6.2 Adult Thoracic-Abdominal Ganglion    8.7 Adult Crop    8.2 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules    8.2 Adult Fat Body    313.3 Adult Salivary Gland no informative data Adult Heart    80.025 Adult VirginFemale Spermatheca    130 Adult InseminatedFemale Spermatheca    390.6 Adult Ovary    6.3 Adult Testis    610 Adult Male Accessory Gland    9.8 Adult Carcass    102.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0039152 expression level Tissue   Expression Level Larval Central Nervous System    37.625 Larval Midgut    21.3 Larval Hindgut    4.8 Larval Malpighian Tubules    9.1 Larval Fat Body    486.4 Larval Salivary Gland    27.9 Larval Trachea    8.825 Larval Carcass no informative data Adult Head    55.9 Adult Eye    27.4 Adult Brain    6.2 Adult Thoracic-Abdominal Ganglion    8.7 Adult Crop    8.2 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules    8.2 Adult Fat Body    313.3 Adult Salivary Gland no informative data Adult Heart    80.025 Adult VirginFemale Spermatheca    130 Adult InseminatedFemale Spermatheca    390.6 Adult Ovary    6.3 Adult Testis    610 Adult Male Accessory Gland    9.8 Adult Carcass    102.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    37.625 Larval Midgut    21.3 Larval Hindgut    4.8 Larval Malpighian Tubules    9.1 Larval Fat Body    486.4 Larval Salivary Gland    27.9 Larval Trachea    8.825 Larval Carcass no informative data Adult Head    55.9 Adult Eye    27.4 Adult Brain    6.2 Adult Thoracic-Abdominal Ganglion    8.7 Adult Crop    8.2 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules    8.2 Adult Fat Body    313.3 Adult Salivary Gland no informative data Adult Heart    80.025 Adult VirginFemale Spermatheca    130 Adult InseminatedFemale Spermatheca    390.6 Adult Ovary    6.3 Adult Testis  610 Adult Male Accessory Gland    9.8 Adult Carcass    102.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    37.625 Larval Midgut    21.3 Larval Hindgut    4.8 Larval Malpighian Tubules    9.1 Larval Fat Body    486.4 Larval Salivary Gland    27.9 Larval Trachea    8.825 Larval Carcass no informative data Adult Head    55.9 Adult Eye    27.4 Adult Brain    6.2 Adult Thoracic-Abdominal Ganglion    8.7 Adult Crop    8.2 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules    8.2 Adult Fat Body    313.3 Adult Salivary Gland no informative data Adult Heart    80.025 Adult VirginFemale Spermatheca    130 Adult InseminatedFemale Spermatheca    390.6 Adult Ovary    6.3 Adult Testis    610 Adult Male Accessory Gland    9.8 Adult Carcass    102.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    37.625 Larval Midgut    21.3 Larval Hindgut    4.8 Larval Malpighian Tubules    9.1 Larval Fat Body    486.4 Larval Salivary Gland    27.9 Larval Trachea    8.825 Larval Carcass no informative data Adult Head    55.9 Adult Eye    27.4 Adult Brain    6.2 Adult Thoracic-Abdominal Ganglion    8.7 Adult Crop    8.2 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules    8.2 Adult Fat Body    313.3 Adult Salivary Gland no informative data Adult Heart    80.025 Adult VirginFemale Spermatheca    130 Adult InseminatedFemale Spermatheca    390.6 Adult Ovary    6.3 Adult Testis    610 Adult Male Accessory Gland    9.8 Adult Carcass    102.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass no informative data Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    55.9   NA  Eye    27.4   NA  Brain    6.2   37.625  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    8.7   NA  Crop    8.2   21.3  Midgut    no informative data   4.8  Hindgut    no informative data   9.1  Malpighian Tubules    8.2   486.4  Fat Body    313.3   27.9  Salivary Gland    no informative data   NA  Heart    80.025   8.825  Trachea    NA   NA  VirginFemale Spermatheca    130   NA  InseminatedFemale Spermatheca    390.6   NA  Ovary    6.3   NA  Testis    610   NA  Male Accessory Gland    9.8   no informative data  Carcass    102.6 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_24
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039152 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6129-RB
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG6129GD11829 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG6129 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG6129 Class Mutagen Stocks Known lesion CG6129GD11829 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG6129KK102209 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6197 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD11829} NA P{KK102209} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
ciliary rootlet inferred from sequence or structural similarity with NCBI:NP_055490 AND inferred from sequence or structural similarity with NCBI:NP_742120 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG6129 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0039152 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42860
Orthologs
Genome-wide drosophilid orthologs	Dana\GF16104 Dere\GG11254 Dgri\GH18493 Dmoj\GI24167 Dper\GL23404 Dpse\GA19376 Dsim\GD21065 Dvir\GJ14200 Dwil\GK11156 Dyak\GE23447
Curated drosophilid orthologs	Dpse\GA19376
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL009915-PA Aedes aegypti (mosquito) AGAP003449-PA Anopheles gambiae (mosquito) XP_624402.1 Apis mellifera (honey bee) XP_001945489.1 Acyrthosiphon pisum (pea aphid) XP_001896619.1 Brugia malayi (roundworm nematode) BGIBMGA006338-PA Bombyx mori (silk worm) ENSBTAP00000040412 Bos taurus (bovine) CBP33775 Caenorhabditis briggsae (nematode) CE31264 Caenorhabditis elegans (worm) ENSCAFP00000023357 Canis familiaris (dog) ENSCINP00000016483 Ciona intestinalis (sea squirt) CPIJ001714 Culex pipens (mosquito) ENSCPOP00000006913 Cavia porcellus (guinea pig) RP37122 Caenorhabditis remanei (nematode) RP43864 Caenorhabditis remanei (nematode) ENSCSAVP00000013838 Ciona savignyi (sedentary tunicate) ENSDARP00000065237 Danio rerio (zebra fish) ENSECAP00000018864 Equus caballus (horse) ENSGACP00000001490 Gymnopilus aculeatus (mushroom) ENSGALP00000002726 Gallus gallus (chicken) ENSP00000364691 Homo sapiens (human) ENSMODP00000034672 Monodelphis domestica (gray opossum) ENSMMUP00000009591 Macaca mulatta (rhesus monkey) ENSMUSP00000099549 Mus musculus (house mouse) XP_001604367.1 Nasonia vitripennis (wasp) ENSOANP00000024590 Ornithorynchus anatinus (platypus) ENSORLP00000022962 Oryzias latipes (japanese killifish) PHUM009033-PA Pediculus humanus (human body louse) PP10428 Pristionchus pacificus (nematode) ENSPPYP00000002108 Pongo pygmaeus (orangutan) ENSPTRP00000000423 Pan troglodytes (chimpanzee) ENSRNOP00000011115 Rattus norvegicus (norway rat) Smp_147890 Schistosoma mansoni (trematode parasite) XP_786339.2 Strongylocentrotus purpuratus (purple sea urchin) XP_966531.2 Tribolium castaneum (red flour beetle) ENSTRUP00000026159 Takifugu rubripes (pufferfish Takifugu) 312.m00019 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000029410 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB18510 NV15303 LH10797 ISCW017899 FBgn0240631 FBgn0213167 FBgn0201415 FBgn0192520 FBgn0181412 FBgn0181411 JGI_V11_309226 JGI_V11_249452 FBgn0079373 FBgn0160994 FBgn0146890 FBgn0125960 FBgn0103555 FBgn0093126 CPIJ001714 BGIBMGA006338 BGIBMGA006337 ACYPI007000 GB30086 GB10082 AGAP003449 AAEL009915 PHUM043110 PHUM376800 GLEAN_06984 GLEAN_00358 GLEAN_14769
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v22694 w1118; P{GD11829}v22694 v22237 w1118; P{GD11829}v22237/TM3
Genomic Clones ( 2 )
	BACR15J11 BACR29F06 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 19 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT16851
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT01596 AT02671 AT05696 AT09643 AT09644 AT12266 AT13063 AT16956 AT17579 AT17930 AT18763 AT25390 AT26781 AT26823 AT29294 LP21286
Other clones	bs40h09 EK308749
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0039152 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42860
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_142959 RefSeq (Proteins) • NP_651216 DDBJ / EMBL / GenBank • AAF56238 AAM50551 AY118691 BF501493 Entrez Gene - A searchable database of RefSeq genes. • 42860 UniProtKB/TrEMBL • Q8MSN3 Q9VCD1
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Protein of unknown function DUF827, plant (IPR008545)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0039152 DRSC - Results from RNAi screens. • FBgn0039152 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0039152 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6129-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0039152 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42860 InParanoid A subset of ortholog calls from InParanoid. • AAEL009915-PA Aedes aegypti (mosquito) AGAP003449-PA Anopheles gambiae (mosquito) XP_624402.1 Apis mellifera (honey bee) XP_001945489.1 Acyrthosiphon pisum (pea aphid) XP_001896619.1 Brugia malayi (roundworm nematode) BGIBMGA006338-PA Bombyx mori (silk worm) ENSBTAP00000040412 Bos taurus (bovine) CBP33775 Caenorhabditis briggsae (nematode) CE31264 Caenorhabditis elegans (worm) ENSCAFP00000023357 Canis familiaris (dog) ENSCINP00000016483 Ciona intestinalis (sea squirt) CPIJ001714 Culex pipens (mosquito) ENSCPOP00000006913 Cavia porcellus (guinea pig) RP37122 Caenorhabditis remanei (nematode) RP43864 Caenorhabditis remanei (nematode) ENSCSAVP00000013838 Ciona savignyi (sedentary tunicate) ENSDARP00000065237 Danio rerio (zebra fish) ENSECAP00000018864 Equus caballus (horse) ENSGACP00000001490 Gymnopilus aculeatus (mushroom) ENSGALP00000002726 Gallus gallus (chicken) ENSP00000364691 Homo sapiens (human) ENSMODP00000034672 Monodelphis domestica (gray opossum) ENSMMUP00000009591 Macaca mulatta (rhesus monkey) ENSMUSP00000099549 Mus musculus (house mouse) XP_001604367.1 Nasonia vitripennis (wasp) ENSOANP00000024590 Ornithorynchus anatinus (platypus) ENSORLP00000022962 Oryzias latipes (japanese killifish) PHUM009033-PA Pediculus humanus (human body louse) PP10428 Pristionchus pacificus (nematode) ENSPPYP00000002108 Pongo pygmaeus (orangutan) ENSPTRP00000000423 Pan troglodytes (chimpanzee) ENSRNOP00000011115 Rattus norvegicus (norway rat) Smp_147890 Schistosoma mansoni (trematode parasite) XP_786339.2 Strongylocentrotus purpuratus (purple sea urchin) XP_966531.2 Tribolium castaneum (red flour beetle) ENSTRUP00000026159 Takifugu rubripes (pufferfish Takifugu) 312.m00019 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000029410 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42860 modMine - Data generated by the modENCODE project. • FBgn0039152 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB18510 NV15303 LH10797 ISCW017899 FBgn0240631 FBgn0213167 FBgn0201415 FBgn0192520 FBgn0181412 FBgn0181411 JGI_V11_309226 JGI_V11_249452 FBgn0079373 FBgn0160994 FBgn0146890 FBgn0125960 FBgn0103555 FBgn0093126 CPIJ001714 BGIBMGA006338 BGIBMGA006337 ACYPI007000 GB30086 GB10082 AGAP003449 AAEL009915 PHUM043110 PHUM376800 GLEAN_06984 GLEAN_00358 GLEAN_14769
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	CG6129 (Mastushita-Sakai et al., 2010, Fujikawa et al., 2009, Buffin and Gho, 2010, Cachero et al., 2011, Wasbrough et al., 2010, Keleman et al., 2009.8.5)
Name Synonym	Rootletin (Cachero et al., 2011)
Secondary FlyBase IDs
References ( 12 )
Research paper	Cachero et al., 2011, PLoS Biol. 9(1): e1000568 The gene regulatory cascade linking proneural specification with differentiation in Drosophila sensory neurons. [FBrf0212891] Buffin and Gho, 2010, PLoS ONE 5(2): e9285 Laser microdissection of sensory organ precursor cells of Drosophila microchaetes. [FBrf0210039] Mastushita-Sakai et al., 2010, Proc. Natl. Acad. Sci. U.S.A. 107(26): 11987--11992 Drosophila Orb2 targets genes involved in neuronal growth, synapse formation, and protein turnover. [FBrf0211209] Fujikawa et al., 2009, Gene 446(1): 11--17 Characteristics of genes up-regulated and down-regulated after 24 h starvation in the head of Drosophila. [FBrf0208557]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Wasbrough et al., 2010, J. Proteomics 73(11): Supplemental Table 1. Mass spectrometry data. [FBrf0213252] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]